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Ronald S. Duman - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
depression, antidepressants, neurogenesis
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Year Citation  Score
2024 Jiang C, DiLeone RJ, Pittenger C, Duman RS. The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions. Translational Psychiatry. 14: 90. PMID 38346984 DOI: 10.1038/s41398-024-02796-0  0.564
2023 Pittenger C, Jiang C, DiLeone R, Duman R. The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions. Research Square. PMID 37886526 DOI: 10.21203/rs.3.rs-3190391/v1  0.564
2023 Banasr M, Codeluppi S, Xu M, Bansal Y, Lepack A, Duric V, Chow M, Muir J, Bagot R, Licznerski P, Wilber S, Sanacora G, Sibille E, Duman R, Pittenger C. Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior. Research Square. PMID 37461693 DOI: 10.21203/rs.3.rs-3093428/v1  0.788
2023 Fogaça MV, Wu M, Li C, Li XY, Duman RS, Picciotto MR. M1 acetylcholine receptors in somatostatin interneurons contribute to GABAergic and glutamatergic plasticity in the mPFC and antidepressant-like responses. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37142667 DOI: 10.1038/s41386-023-01583-7  0.366
2023 Jaggar M, Ghosh S, Janakiraman B, Chatterjee A, Maheshwari M, Dewan V, Hare B, Deb S, Figueiredo D, Duman RS, Vaidya VA. Influence of chronic electroconvulsive seizures on plasticity-associated gene expression and perineuronal nets within the hippocampi of young adult and middle-aged Sprague-Dawley rats. The International Journal of Neuropsychopharmacology. PMID 36879414 DOI: 10.1093/ijnp/pyad008  0.795
2022 Lee B, Pothula S, Wu M, Kang H, Girgenti MJ, Picciotto MR, DiLeone RJ, Taylor JR, Duman RS. Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear. Molecular Psychiatry. PMID 35418600 DOI: 10.1038/s41380-022-01498-7  0.545
2021 Langreck C, Wauson E, Nerland D, Lamb B, Folkerts T, Winter L, Lu E, Tague S, McCarson KE, Ploski JE, Banasr M, Duman RS, Roland MM, Babich V, Di Sole F, et al. Hippocampal mitogen-activated protein kinase phosphatase-1 regulates behavioral and systemic effects of chronic corticosterone administration. Biochemical Pharmacology. 114617. PMID 34023293 DOI: 10.1016/j.bcp.2021.114617  0.818
2021 Huzian O, Baka J, Csakvari E, Dobos N, Leranth C, Siklos L, Duman RS, Farkas T, Hajszan T. Stress Resilience Is Associated with Hippocampal Synaptoprotection in the Female Rat Learned Helplessness Paradigm. Neuroscience. PMID 33524494 DOI: 10.1016/j.neuroscience.2021.01.029  0.311
2021 Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Author Correction: Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Nature Communications. 12: 370. PMID 33420087 DOI: 10.1038/s41467-020-20634-x  0.496
2020 Lee B, Pothula S, Duman RS. NMDAR modulators as rapid antidepressants: Converging and distinct signaling mechanisms. Integrative Clinical Medicine. 4. PMID 34381955 DOI: 10.15761/icm.1000173  0.545
2020 Pothula S, Liu RJ, Wu M, Sliby AN, Picciotto MR, Banerjee P, Duman RS. Positive modulation of NMDA receptors by AGN-241751 exerts rapid antidepressant-like effects via excitatory neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33059355 DOI: 10.1038/s41386-020-00882-7  0.379
2020 Xu J, Liu RJ, Fahey S, Frick L, Leckman J, Vaccarino F, Duman RS, Williams K, Swedo S, Pittenger C. Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity. The American Journal of Psychiatry. appiajp202019070698. PMID 32539528 DOI: 10.1176/Appi.Ajp.2020.19070698  0.548
2020 Pothula S, Kato T, Liu RJ, Wu M, Gerhard D, Shinohara R, Sliby AN, Chowdhury GMI, Behar KL, Sanacora G, Banerjee P, Duman RS. Cell-type specific modulation of NMDA receptors triggers antidepressant actions. Molecular Psychiatry. PMID 32488125 DOI: 10.1038/s41380-020-0796-3  0.425
2020 Fukumoto K, Fogaça MV, Liu RJ, Duman CH, Li XY, Chaki S, Duman RS. Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT receptor stimulation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32396921 DOI: 10.1038/S41386-020-0705-0  0.373
2020 Krystal JH, Charney DS, Duman RS. A New Rapid-Acting Antidepressant. Cell. 181: 7. PMID 32243798 DOI: 10.1016/J.Cell.2020.02.033  0.351
2020 Ali F, Shao LX, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromise by a nonsense Shank3 mutation. Molecular Psychiatry. PMID 32161363 DOI: 10.1038/S41380-020-0708-6  0.586
2020 Hare BD, Duman RS. Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions. Molecular Psychiatry. PMID 32086434 DOI: 10.1038/s41380-020-0685-9  0.432
2020 Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Nature Communications. 11: 72. PMID 31911591 DOI: 10.1038/S41467-019-13809-8  0.617
2020 Deyama S, Li XY, Duman RS. Neuron-specific deletion of VEGF or its receptor Flk-1 impairs recognition memory. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 31902568 DOI: 10.1016/J.Euroneuro.2019.11.002  0.316
2020 Price RB, Duman R. Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model. Molecular Psychiatry. 25: 530-543. PMID 31801966 DOI: 10.1038/S41380-019-0615-X  0.35
2020 Stone L, Girgenti M, Krystal J, Duman R. Neural Transcriptomic Alterations Associated With Neuropeptide Y and Ghrelin in Posttraumatic Stress Disorder Biological Psychiatry. 87: S421-S422. DOI: 10.1016/J.Biopsych.2020.02.1075  0.303
2019 Deyama S, Duman RS. Neurotrophic mechanisms underlying the rapid and sustained antidepressant actions of ketamine. Pharmacology, Biochemistry, and Behavior. 188: 172837. PMID 31830487 DOI: 10.1016/j.pbb.2019.172837  0.475
2019 Duman RS, Deyama S, Fogaça MV. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European Journal of Neuroscience. PMID 31811669 DOI: 10.1111/ejn.14630  0.491
2019 Gerhard DM, Pothula S, Liu RJ, Wu M, Li XY, Girgenti MJ, Taylor SR, Duman CH, Delpire E, Picciotto M, Wohleb ES, Duman RS. GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions. The Journal of Clinical Investigation. PMID 31743111 DOI: 10.1172/Jci130808  0.727
2019 Kato T, Duman RS. Rapastinel, a novel glutamatergic agent with ketamine-like antidepressant actions: Convergent mechanisms. Pharmacology, Biochemistry, and Behavior. 172827. PMID 31733218 DOI: 10.1016/j.pbb.2019.172827  0.376
2019 Girgenti MJ, Wohleb ES, Mehta S, Ghosal S, Fogaca MV, Duman RS. Prefrontal cortex interneurons display dynamic sex-specific stress-induced transcriptomes. Translational Psychiatry. 9: 292. PMID 31712551 DOI: 10.1038/s41398-019-0642-z  0.75
2019 Ghosal S, Duman CH, Liu RJ, Wu M, Terwilliger R, Girgenti MJ, Wohleb E, Fogaca MV, Teichman EM, Hare B, Duman RS. Ketamine rapidly reverses stress-induced impairments in GABAergic transmission in the prefrontal cortex in male rodents. Neurobiology of Disease. 104669. PMID 31707118 DOI: 10.1016/j.nbd.2019.104669  0.73
2019 Fogaça MV, Fukumoto K, Franklin T, Liu RJ, Duman CH, Vitolo OV, Duman RS. N-Methyl-D-aspartate receptor antagonist d-methadone produces rapid, mTORC1-dependent antidepressant effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31454827 DOI: 10.1038/s41386-019-0501-x  0.382
2019 Kato T, Pothula S, Liu RJ, Duman CH, Terwilliger R, Vlasuk GP, Saiah E, Hahm S, Duman RS. Sestrin modulator NV-5138 produces rapid antidepressant effects via direct mTORC1 activation. The Journal of Clinical Investigation. 130. PMID 30990795 DOI: 10.1172/JCI126859  0.458
2019 Holmes SE, Scheinost D, Finnema SJ, Naganawa M, Davis MT, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Lower synaptic density is associated with depression severity and network alterations. Nature Communications. 10: 1529. PMID 30948709 DOI: 10.1038/S41467-019-09562-7  0.341
2019 Duman RS, Sanacora G, Krystal JH. Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments. Neuron. 102: 75-90. PMID 30946828 DOI: 10.1016/J.Neuron.2019.03.013  0.46
2019 Fogaça MV, Duman RS. Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions. Frontiers in Cellular Neuroscience. 13: 87. PMID 30914923 DOI: 10.3389/fncel.2019.00087  0.468
2019 Duman RS, Shinohara R, Fogaça MV, Hare B. Neurobiology of rapid-acting antidepressants: convergent effects on GluA1-synaptic function. Molecular Psychiatry. PMID 30894661 DOI: 10.1038/s41380-019-0400-x  0.435
2019 Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS. Ketamine: A Paradigm Shift for Depression Research and Treatment. Neuron. 101: 774-778. PMID 30844397 DOI: 10.1016/J.Neuron.2019.02.005  0.367
2019 Hare BD, Shinohara R, Liu RJ, Pothula S, DiLeone RJ, Duman RS. Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects. Nature Communications. 10: 223. PMID 30644390 DOI: 10.1038/s41467-018-08168-9  0.465
2019 Deyama S, Bang E, Wohleb ES, Li XY, Kato T, Gerhard DM, Dutheil S, Dwyer JM, Taylor SR, Picciotto MR, Duman RS. Role of Neuronal VEGF Signaling in the Prefrontal Cortex in the Rapid Antidepressant Effects of Ketamine. The American Journal of Psychiatry. appiajp201817121368. PMID 30606046 DOI: 10.1176/Appi.Ajp.2018.17121368  0.809
2019 Holmes S, Scheinost D, Finnema S, Naganawa M, Davis M, DellaGioia N, Nabulsi N, Matuskey D, Angarita G, Pietrzak R, Duman R, Sanacora G, Krystal J, Carson R, Esterlis I. 142. Synaptic Density Alterations are Associated With Depression Severity and Network Alterations Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.156  0.325
2018 Deyama S, Bang E, Kato T, Li XY, Duman RS. Neurotrophic and Antidepressant Actions of Brain-Derived Neurotrophic Factor Require Vascular Endothelial Growth Factor. Biological Psychiatry. PMID 30712809 DOI: 10.1016/J.Biopsych.2018.12.014  0.331
2018 Fukumoto K, Fogaça MV, Liu RJ, Duman C, Kato T, Li XY, Duman RS. Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2,6)-hydroxynorketamine. Proceedings of the National Academy of Sciences of the United States of America. PMID 30559184 DOI: 10.1073/Pnas.1814709116  0.435
2018 Simard S, Shail P, MacGregor J, El Sayed M, Duman RS, Vaccarino FM, Salmaso N. Fibroblast growth factor 2 is necessary for the antidepressant effects of fluoxetine. Plos One. 13: e0204980. PMID 30273396 DOI: 10.1371/Journal.Pone.0204980  0.443
2018 Duman RS, Girgenti MJ. Molecular and cellular studies of PTSD: Postmortem transcriptome analysis and novel therapeutic targets. Journal of Neuroscience Research. PMID 30136735 DOI: 10.1002/jnr.24306  0.318
2018 Gerhard DM, Duman RS. Rapid-Acting Antidepressants: Mechanistic Insights and Future Directions. Current Behavioral Neuroscience Reports. 5: 36-47. PMID 30034992 DOI: 10.1007/S40473-018-0139-8  0.332
2018 Gerhard DM, Duman RS. Sex-Specific Molecular Changes in Depression. Biological Psychiatry. 84: 2-4. PMID 29929577 DOI: 10.1016/j.biopsych.2018.05.005  0.337
2018 Duman RS. Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide. F1000research. 7. PMID 29899972 DOI: 10.12688/f1000research.14344.1  0.396
2018 Abdallah CG, Sanacora G, Duman RS, Krystal JH. The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation? Pharmacology & Therapeutics. PMID 29803629 DOI: 10.1016/J.Pharmthera.2018.05.010  0.437
2018 Zanos P, Thompson SM, Duman RS, Zarate CA, Gould TD. Convergent Mechanisms Underlying Rapid Antidepressant Action. Cns Drugs. PMID 29516301 DOI: 10.1007/S40263-018-0492-X  0.427
2018 Fogaça MV, de Campos AC, Coelho LD, Duman RS, Guimarães FS. The anxiolytic effects of cannabidiol in chronically stressed mice are mediated by the endocannabinoid system: Role of neurogenesis and dendritic remodeling. Neuropharmacology. PMID 29510186 DOI: 10.1016/J.Neuropharm.2018.03.001  0.414
2018 Jeanneteau F, Barrère C, Vos M, De Vries CJ, Rouillard C, Levesque D, Dromard Y, Moisan MP, Duric V, Franklin TC, Duman RS, Lewis DA, Ginsberg SD, Arango-Lievano M. The stress-induced transcription factor NR4A1 adjusts mitochondrial function and synapse number in prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29295823 DOI: 10.1523/Jneurosci.2793-17.2017  0.723
2018 Franklin T, Duman R. F159. Cell -Specific Ablation of RAGE Alters Susceptibility to Depressive-Like Behaviors After Chronic Unpredictable Stress Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.773  0.393
2018 Georgiou P, Zanos P, Jenne C, Highland J, Gerhard D, Duman R, Gould T. F102. Human Experimenter Sex Modulates Mouse Behavioral Responses to Stress and to the Antidepressant Ketamine Biological Psychiatry. 83: S277. DOI: 10.1016/J.Biopsych.2018.02.715  0.307
2018 Hare B, Liu R, Shinohara R, DiLeone R, Duman R. F98. Stimulation of Drd1 Expressing Principle Neurons in the Prefrontal Cortex Produces Rapid and Long-Lasting Antidepressant Effects and is Necessary for the Response to Ketamine Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.711  0.345
2018 Girgenti M, Cruz D, Williamson D, Friedman M, Krystal J, Duman R. T103. Transcriptome Alterations for Posttraumatic Stress Disorder in Human Prefrontal Cortex Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.439  0.302
2018 Duman R. 186. Initial Cellular Trigger of Rapid Acting Antidepressants: Direct and Indirect Glutamatergic Mechanisms Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.205  0.34
2017 Thomas AM, Duman RS. Novel rapid-acting antidepressants: molecular and cellular signaling mechanisms. Neuronal Signaling. 1. PMID 30034823 DOI: 10.1042/NS20170010  0.311
2017 Bath KG, Russo SJ, Pleil KE, Wohleb ES, Duman RS, Radley JJ. Circuit and synaptic mechanisms of repeated stress: Perspectives from differing contexts, duration, and development. Neurobiology of Stress. 7: 137-151. PMID 29276735 DOI: 10.1016/J.Ynstr.2017.05.001  0.718
2017 Girgenti MJ, Duman RS. Transcriptome Alterations in Posttraumatic Stress Disorder. Biological Psychiatry. PMID 29128043 DOI: 10.1016/j.biopsych.2017.09.023  0.307
2017 Franklin T, Xu C, Duman RS. Depression and sterile inflammation: essential role of danger associated molecular patterns. Brain, Behavior, and Immunity. PMID 29102801 DOI: 10.1016/j.bbi.2017.10.025  0.413
2017 Girgenti MJ, Hare BD, Ghosal S, Duman RS. Molecular and Cellular Effects of Traumatic Stress: Implications for PTSD. Current Psychiatry Reports. 19: 85. PMID 28944401 DOI: 10.1007/s11920-017-0841-3  0.305
2017 Duman RS. Sex-specific disease-associated modules for depression. Nature Medicine. 23: 1015-1017. PMID 28886002 DOI: 10.1038/nm.4391  0.349
2017 Franklin TC, Wohleb ES, Zhang Y, Fogaça M, Hare B, Duman RS. Persistent Increase in Microglial RAGE Contributes to Chronic Stress-Induced Priming of Depressive-like Behavior. Biological Psychiatry. PMID 28882317 DOI: 10.1016/j.biopsych.2017.06.034  0.737
2017 Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS. Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic. Current Psychiatry Reports. 19: 74. PMID 28844076 DOI: 10.1007/S11920-017-0829-Z  0.323
2017 Banasr M, Lepack A, Fee C, Duric V, Maldonado-Aviles J, DiLeone R, Sibille E, Duman RS, Sanacora G. Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28835932  0.73
2017 Yamanashi T, Iwata M, Kamiya N, Tsunetomi K, Kajitani N, Wada N, Iitsuka T, Yamauchi T, Miura A, Pu S, Shirayama Y, Watanabe K, Duman RS, Kaneko K. Beta-hydroxybutyrate, an endogenic NLRP3 inflammasome inhibitor, attenuates stress-induced behavioral and inflammatory responses. Scientific Reports. 7: 7677. PMID 28794421 DOI: 10.1038/s41598-017-08055-1  0.397
2017 Ghosal S, Bang E, Yue W, Hare BD, Lepack AE, Girgenti MJ, Duman RS. Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of Scopolamine. Biological Psychiatry. PMID 28751069 DOI: 10.1016/j.biopsych.2017.06.017  0.441
2017 Holmes SE, Girgenti MJ, Davis MT, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Southwick S, Duman RS, Carson RE, Krystal JH, Esterlis I. Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716937 DOI: 10.1073/Pnas.1701749114  0.332
2017 Wohleb ES, Terwilliger R, Duman CH, Duman RS. Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior. Biological Psychiatry. PMID 28697890 DOI: 10.1016/j.biopsych.2017.05.026  0.751
2017 Hare BD, Ghosal S, Duman RS. Rapid Acting Antidepressants in Chronic Stress Models: Molecular and Cellular Mechanisms. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 28649673  0.317
2017 Duric V, Banasr M, Franklin T, Lepack A, Adham N, Kiss B, Gyertyán I, Duman RS. Cariprazine Exhibits Anxiolytic and Dopamine D3 Receptor-Dependent Antidepressant Effects in the Chronic Stress Model. The International Journal of Neuropsychopharmacology. PMID 28531264 DOI: 10.1093/ijnp/pyx038  0.685
2017 Hufgard JR, Williams MT, Skelton MR, Grubisha O, Ferreira FM, Sanger H, Wright ME, Reed-Kessler TM, Rasmussen K, Duman RS, Vorhees CV. Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a. Psychopharmacology. PMID 28337525 DOI: 10.1007/S00213-017-4587-8  0.367
2017 Harmer CJ, Duman RS, Cowen PJ. How do antidepressants work? New perspectives for refining future treatment approaches. The Lancet. Psychiatry. PMID 28153641 DOI: 10.1016/S2215-0366(17)30015-9  0.356
2017 Ghosal S, Hare B, Duman RS. Prefrontal Cortex GABAergic Deficits and Circuit Dysfunction in the Pathophysiology and Treatment of Chronic Stress and Depression. Current Opinion in Behavioral Sciences. 14: 1-8. PMID 27812532 DOI: 10.1016/j.cobeha.2016.09.012  0.426
2017 Wohleb ES, Terwilliger R, Duman CH, Duman RS. 511. Stress-Induced Neuronal CSF1 Provokes Microglia-Mediated Dendritic Remodeling and Depressive-Like Behavior Biological Psychiatry. 81: 38. DOI: 10.1016/J.Biopsych.2017.02.1119  0.448
2016 Girgenti MJ, Ghosal S, LoPresto D, Taylor JR, Duman RS. Ketamine accelerates fear extinction via mTORC1 signaling. Neurobiology of Disease. PMID 28043916 DOI: 10.1016/j.nbd.2016.12.026  0.39
2016 Baka J, Csakvari E, Huzian O, Dobos N, Siklos L, Leranth C, MacLusky NJ, Duman RS, Hajszan T. Stress induces equivalent remodeling ofhippocampalspine synapses in a simulated postpartum environment and in a female rat model of major depression. Neuroscience. PMID 28012870 DOI: 10.1016/J.Neuroscience.2016.12.021  0.419
2016 Kabir ZD, Lee AS, Burgdorf CE, Fischer D, Rajadhyaksha AM, Mok E, Rizzo B, Rice RC, Singh K, Ota KT, Gerhard DM, Schierberl KC, Glass M, Duman RS, Rajadhyaksha AM. Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27922594 DOI: 10.1038/Npp.2016.271  0.787
2016 Liu RJ, Duman C, Kato T, Hare B, Lopresto D, Bang E, Burgdorf J, Moskal J, Taylor J, Aghajanian G, Duman RS. GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27634355 DOI: 10.1038/Npp.2016.202  0.4
2016 Lepack AE, Bang E, Lee B, Dwyer JM, Duman RS. Fast-acting antidepressants rapidly stimulate ERK signaling and BDNF release in primary neuronal cultures. Neuropharmacology. PMID 27634096 DOI: 10.1016/J.Neuropharm.2016.09.011  0.721
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/J.Biopsych.2016.05.004  0.613
2016 Wohleb ES, Franklin T, Iwata M, Duman RS. Integrating neuroimmune systems in the neurobiology of depression. Nature Reviews. Neuroscience. PMID 27277867 DOI: 10.1038/nrn.2016.69  0.728
2016 Wohleb ES, Wu M, Gerhard DM, Taylor SR, Picciotto MR, Alreja M, Duman RS. GABA interneurons mediate the rapid antidepressant-like effects of scopolamine. The Journal of Clinical Investigation. PMID 27270172 DOI: 10.1172/Jci85033  0.73
2016 Salmaso N, Stevens HE, McNeill J, ElSayed M, Ren Q, Maragnoli ME, Schwartz ML, Tomasi S, Sapolsky RM, Duman R, Vaccarino FM. Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors. Biological Psychiatry. PMID 27133954 DOI: 10.1016/J.Biopsych.2016.02.026  0.609
2016 Chowdhury GM, Zhang J, Thomas M, Banasr M, Ma X, Pittman B, Bristow L, Schaeffer E, Duman RS, Rothman DL, Behar KL, Sanacora G. Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects. Molecular Psychiatry. PMID 27067013 DOI: 10.1038/mp.2016.34  0.362
2016 Wohleb ES, Gerhard D, Thomas A, Duman RS. Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine. Current Neuropharmacology. PMID 26955968 DOI: 10.2174/1570159X14666160309114549  0.749
2016 Duman RS, Aghajanian GK, Sanacora G, Krystal JH. Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nature Medicine. 22: 238-49. PMID 26937618 DOI: 10.1038/Nm.4050  0.433
2016 Gerhard DM, Wohleb ES, Duman RS. Emerging Treatment Mechanisms for Depression: Focus on Glutamate and Synaptic Plasticity. Drug Discovery Today. PMID 26854424 DOI: 10.1016/j.drudis.2016.01.016  0.752
2016 Wohleb ES, Duman RS. Abstract # 1772 Microglia-mediated dendritic remodeling is associated with alterations in neuron-derived signals after chronic unpredictable stress Brain Behavior and Immunity. 57. DOI: 10.1016/J.Bbi.2016.07.065  0.418
2015 Iwata M, Ota KT, Li XY, Sakaue F, Li N, Dutheil S, Banasr M, Duric V, Yamanashi T, Kaneko K, Rasmussen K, Glasebrook A, Koester A, Song D, Jones KA, ... ... Duman RS, et al. Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor. Biological Psychiatry. PMID 26831917 DOI: 10.1016/J.Biopsych.2015.11.026  0.804
2015 Dutheil S, Ota KT, Wohleb ES, Rasmussen K, Duman RS. High Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26658303 DOI: 10.1038/Npp.2015.357  0.812
2015 Choi M, Lee SH, Wang SE, Ko SY, Song M, Choi JS, Kim YS, Duman RS, Son H. Ketamine produces antidepressant-like effects through phosphorylation-dependent nuclear export of histone deacetylase 5 (HDAC5) in rats. Proceedings of the National Academy of Sciences of the United States of America. PMID 26647181 DOI: 10.1073/pnas.1513913112  0.415
2015 Licznerski P, Duric V, Banasr M, Alavian KN, Ota KT, Kang HJ, Jonas EA, Ursano R, Krystal JH, Duman RS. Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress. Plos Biology. 13: e1002282. PMID 26506154 DOI: 10.1371/Journal.Pbio.1002282  0.82
2015 Wu MV, Sahay A, Duman RS, Hen R. Functional differentiation of adult-born neurons along the septotemporal axis of the dentate gyrus. Cold Spring Harbor Perspectives in Biology. 7: a018978. PMID 26238355 DOI: 10.1101/Cshperspect.A018978  0.351
2015 Navarria A, Wohleb ES, Voleti B, Ota KT, Dutheil S, Lepack AE, Dwyer JM, Fuchikami M, Becker A, Drago F, Duman RS. Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors. Neurobiology of Disease. 82: 254-261. PMID 26102021 DOI: 10.1016/J.Nbd.2015.06.012  0.811
2015 Fuchikami M, Thomas A, Liu R, Wohleb ES, Land BB, DiLeone RJ, Aghajanian GK, Duman RS. Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. 112: 8106-11. PMID 26056286 DOI: 10.1073/Pnas.1414728112  0.72
2015 Dwyer JM, Maldonado-Avilés JG, Lepack AE, DiLeone RJ, Duman RS. Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 112: 6188-93. PMID 25918363 DOI: 10.1073/Pnas.1505289112  0.7
2015 Liu RJ, Ota KT, Dutheil S, Duman RS, Aghajanian GK. Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2066-75. PMID 25759300 DOI: 10.1038/Npp.2015.70  0.822
2015 Han J, Calvo CF, Kang TH, Baker KL, Park JH, Parras C, Levittas M, Birba U, Pibouin-Fragner L, Fragner P, Bilguvar K, Duman RS, Nurmi H, Alitalo K, Eichmann AC, et al. Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans. Cell Reports. 10: 1158-72. PMID 25704818 DOI: 10.1016/J.Celrep.2015.01.049  0.31
2015 Duman CH, Duman RS. Spine synapse remodeling in the pathophysiology and treatment of depression. Neuroscience Letters. 601: 20-9. PMID 25582786 DOI: 10.1016/j.neulet.2015.01.022  0.472
2015 Xu M, Kobets A, Du JC, Lennington J, Li L, Banasr M, Duman RS, Vaccarino FM, DiLeone RJ, Pittenger C. Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 893-8. PMID 25561540 DOI: 10.1073/Pnas.1419533112  0.596
2015 Lepack AE, Fuchikami M, Dwyer JM, Banasr M, Duman RS. BDNF release is required for the behavioral actions of ketamine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25539510 DOI: 10.1093/Ijnp/Pyu033  0.628
2015 Abdallah CG, Sanacora G, Duman RS, Krystal JH. Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics. Annual Review of Medicine. 66: 509-23. PMID 25341010 DOI: 10.1146/Annurev-Med-053013-062946  0.398
2015 Ota KT, Andres W, Lewis DA, Stockmeier CA, Duman RS. BICC1 expression is elevated in depressed subjects and contributes to depressive behavior in rodents. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 711-8. PMID 25178406 DOI: 10.1038/Npp.2014.227  0.833
2015 Navarria A, Wohleb ES, Voleti B, Ota KT, Dutheil S, Lepack AE, Dwyer JM, Fuchikami M, Becker A, Drago F, Duman RS. Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors Neurobiology of Disease. 82: 254-261. DOI: 10.1016/j.nbd.2015.06.012  0.783
2014 Choi M, Wang SE, Ko SY, Kang HJ, Chae SY, Lee SH, Kim YS, Duman RS, Son H. Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats. Plos One. 9: e109253. PMID 25340772 DOI: 10.1371/journal.pone.0109253  0.445
2014 Duman RS. Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues in Clinical Neuroscience. 16: 11-27. PMID 24733968  0.379
2014 Ota KT, Liu RJ, Voleti B, Maldonado-Aviles JG, Duric V, Iwata M, Dutheil S, Duman C, Boikess S, Lewis DA, Stockmeier CA, DiLeone RJ, Rex C, Aghajanian GK, Duman RS. REDD1 is essential for stress-induced synaptic loss and depressive behavior. Nature Medicine. 20: 531-5. PMID 24728411 DOI: 10.1038/Nm.3513  0.835
2014 Monsey MS, Boyle LM, Zhang ML, Nguyen CP, Kronman HG, Ota KT, Duman RS, Taylor JR, Schafe GE. Chronic corticosterone exposure persistently elevates the expression of memory-related genes in the lateral amygdala and enhances the consolidation of a Pavlovian fear memory. Plos One. 9: e91530. PMID 24618807 DOI: 10.1371/Journal.Pone.0091530  0.786
2014 Duman RS. Neurobiology of stress, depression, and rapid acting antidepressants: remodeling synaptic connections. Depression and Anxiety. 31: 291-6. PMID 24616149 DOI: 10.1002/da.22227  0.492
2014 Duman RS, Aghajanian GK. Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3β. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 233. PMID 24317309 DOI: 10.1038/npp.2013.217  0.434
2013 Dwyer JM, Lepack AE, Duman RS. mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure. Journal of Molecular Psychiatry. 1: 15. PMID 25408908 DOI: 10.1186/2049-9256-1-15  0.634
2013 Duman RS. Neurobiological advances identify novel antidepressant targets. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 12: 207-9. PMID 24096777 DOI: 10.1002/wps.20058  0.364
2013 Zarate C, Duman RS, Liu G, Sartori S, Quiroz J, Murck H. New paradigms for treatment-resistant depression. Annals of the New York Academy of Sciences. 1292: 21-31. PMID 23876043 DOI: 10.1111/Nyas.12223  0.431
2013 Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS. Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses. Biological Psychiatry. 74: 742-9. PMID 23751205 DOI: 10.1016/J.Biopsych.2013.04.025  0.59
2013 Krystal JH, Sanacora G, Duman RS. Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond. Biological Psychiatry. 73: 1133-41. PMID 23726151 DOI: 10.1016/J.Biopsych.2013.03.026  0.373
2013 Liu RJ, Fuchikami M, Dwyer JM, Lepack AE, Duman RS, Aghajanian GK. GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2268-77. PMID 23680942 DOI: 10.1038/Npp.2013.128  0.647
2013 Newton SS, Fournier NM, Duman RS. Vascular growth factors in neuropsychiatry. Cellular and Molecular Life Sciences : Cmls. 70: 1739-52. PMID 23475069 DOI: 10.1007/s00018-013-1281-9  0.733
2013 Fournier NM, Duman RS. Illuminating hippocampal control of fear memory and anxiety. Neuron. 77: 803-6. PMID 23473311 DOI: 10.1016/j.neuron.2013.02.017  0.722
2013 Duman RS. Remodeling chromatin and synapses in depression. Nature Medicine. 19: 267. PMID 23467234 DOI: 10.1038/nm.3125  0.383
2013 Dwyer JM, Duman RS. Activation of mammalian target of rapamycin and synaptogenesis: role in the actions of rapid-acting antidepressants. Biological Psychiatry. 73: 1189-98. PMID 23295207 DOI: 10.1016/J.Biopsych.2012.11.011  0.675
2013 Iwata M, Ota KT, Duman RS. The inflammasome: pathways linking psychological stress, depression, and systemic illnesses. Brain, Behavior, and Immunity. 31: 105-14. PMID 23261775 DOI: 10.1016/J.Bbi.2012.12.008  0.78
2013 Licznerski P, Duman RS. Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression. Neuroscience. 251: 33-50. PMID 23036622 DOI: 10.1016/j.neuroscience.2012.09.057  0.461
2013 Ota KT, Duman RS. Environmental and pharmacological modulations of cellular plasticity: role in the pathophysiology and treatment of depression. Neurobiology of Disease. 57: 28-37. PMID 22691453 DOI: 10.1016/J.Nbd.2012.05.022  0.806
2013 Duric V, Duman RS. Depression and treatment response: dynamic interplay of signaling pathways and altered neural processes. Cellular and Molecular Life Sciences : Cmls. 70: 39-53. PMID 22585060 DOI: 10.1007/s00018-012-1020-7  0.741
2013 Duric V, Banasr M, Stockmeier CA, Simen AA, Newton SS, Overholser JC, Jurjus GJ, Dieter L, Duman RS. Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 69-82. PMID 22339950 DOI: 10.1017/S1461145712000016  0.791
2013 Sanacora G, Duman RS. The revolution in rapid-acting antidepressants Biological Psychiatry. 73: 1123-1124. DOI: 10.1016/j.biopsych.2013.04.020  0.353
2012 Duman RS, Aghajanian GK. Synaptic dysfunction in depression: potential therapeutic targets. Science (New York, N.Y.). 338: 68-72. PMID 23042884 DOI: 10.1126/science.1222939  0.476
2012 Kang HJ, Voleti B, Hajszan T, Rajkowska G, Stockmeier CA, Licznerski P, Lepack A, Majik MS, Jeong LS, Banasr M, Son H, Duman RS. Decreased expression of synapse-related genes and loss of synapses in major depressive disorder. Nature Medicine. 18: 1413-7. PMID 22885997 DOI: 10.1038/Nm.2886  0.747
2012 Duman RS, Li N. A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2475-84. PMID 22826346 DOI: 10.1098/Rstb.2011.0357  0.654
2012 Son H, Banasr M, Choi M, Chae SY, Licznerski P, Lee B, Voleti B, Li N, Lepack A, Fournier NM, Lee KR, Lee IY, Kim J, Kim JH, Kim YH, ... ... Duman RS, et al. Neuritin produces antidepressant actions and blocks the neuronal and behavioral deficits caused by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. 109: 11378-83. PMID 22733766 DOI: 10.1073/Pnas.1201191109  0.838
2012 Fournier NM, Lee B, Banasr M, Elsayed M, Duman RS. Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling. Neuropharmacology. 63: 642-52. PMID 22580375 DOI: 10.1016/J.Neuropharm.2012.04.033  0.799
2012 Elsayed M, Banasr M, Duric V, Fournier NM, Licznerski P, Duman RS. Antidepressant effects of fibroblast growth factor-2 in behavioral and cellular models of depression. Biological Psychiatry. 72: 258-65. PMID 22513055 DOI: 10.1016/J.Biopsych.2012.03.003  0.829
2012 Duman RS, Voleti B. Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends in Neurosciences. 35: 47-56. PMID 22217452 DOI: 10.1016/j.tins.2011.11.004  0.492
2012 Dwyer JM, Lepack AE, Duman RS. mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 429-34. PMID 22114864 DOI: 10.1017/S1461145711001702  0.656
2012 Liu RJ, Lee FS, Li XY, Bambico F, Duman RS, Aghajanian GK. Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. Biological Psychiatry. 71: 996-1005. PMID 22036038 DOI: 10.1016/J.Biopsych.2011.09.030  0.381
2012 Zhao C, Warner-Schmidt J, Duman RS, Gage FH. Electroconvulsive seizure promotes spine maturation in newborn dentate granule cells in adult rat. Developmental Neurobiology. 72: 937-42. PMID 21976455 DOI: 10.1002/Dneu.20986  0.736
2012 Voleti B, Tanis KQ, Newton SS, Duman RS. Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression. Biological Psychiatry. 71: 51-8. PMID 21937024 DOI: 10.1016/J.Biopsych.2011.08.004  0.431
2012 Duman RS, Li N, Liu RJ, Duric V, Aghajanian G. Signaling pathways underlying the rapid antidepressant actions of ketamine. Neuropharmacology. 62: 35-41. PMID 21907221 DOI: 10.1016/J.Neuropharm.2011.08.044  0.794
2012 Fournier NM, Duman RS. Role of vascular endothelial growth factor in adult hippocampal neurogenesis: implications for the pathophysiology and treatment of depression. Behavioural Brain Research. 227: 440-9. PMID 21536078 DOI: 10.1016/j.bbr.2011.04.022  0.758
2012 Pittenger C, Nestler EJ, Duman RS. Cyclic Nucleotides in the Nervous System Basic Neurochemistry. 423-441. DOI: 10.1016/B978-0-12-374947-5.00022-5  0.451
2012 Zachariou V, Duman RS, Nestler EJ. G Proteins Basic Neurochemistry. 411-422. DOI: 10.1016/B978-0-12-374947-5.00021-3  0.443
2011 Banasr M, Dwyer JM, Duman RS. Cell atrophy and loss in depression: reversal by antidepressant treatment. Current Opinion in Cell Biology. 23: 730-7. PMID 21996102 DOI: 10.1016/J.Ceb.2011.09.002  0.677
2011 Schmidt HD, Shelton RC, Duman RS. Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2375-94. PMID 21814182 DOI: 10.1038/npp.2011.151  0.392
2011 Li N, Liu RJ, Dwyer JM, Banasr M, Lee B, Son H, Li XY, Aghajanian G, Duman RS. Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biological Psychiatry. 69: 754-61. PMID 21292242 DOI: 10.1016/J.Biopsych.2010.12.015  0.785
2011 Hermes G, Li N, Duman C, Duman R. Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats. Physiology & Behavior. 104: 354-9. PMID 21185848 DOI: 10.1016/J.Physbeh.2010.12.019  0.539
2010 Duric V, Banasr M, Licznerski P, Schmidt HD, Stockmeier CA, Simen AA, Newton SS, Duman RS. A negative regulator of MAP kinase causes depressive behavior. Nature Medicine. 16: 1328-32. PMID 20953200 DOI: 10.1038/Nm.2219  0.808
2010 Li N, Lee B, Liu RJ, Banasr M, Dwyer JM, Iwata M, Li XY, Aghajanian G, Duman RS. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science (New York, N.Y.). 329: 959-64. PMID 20724638 DOI: 10.1126/Science.1190287  0.786
2010 Schmidt HD, Duman RS. Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2378-91. PMID 20686454 DOI: 10.1038/npp.2010.114  0.438
2010 Okamoto H, Voleti B, Banasr M, Sarhan M, Duric V, Girgenti MJ, Dileone RJ, Newton SS, Duman RS. Wnt2 expression and signaling is increased by different classes of antidepressant treatments. Biological Psychiatry. 68: 521-7. PMID 20570247 DOI: 10.1016/J.Biopsych.2010.04.023  0.704
2010 Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS. Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 107: 2669-74. PMID 20133768 DOI: 10.1073/Pnas.0910658107  0.718
2010 Girgenti MJ, Nisenbaum LK, Bymaster F, Terwilliger R, Duman RS, Newton SS. Antipsychotic-induced gene regulation in multiple brain regions. Journal of Neurochemistry. 113: 175-87. PMID 20070867 DOI: 10.1111/j.1471-4159.2010.06585.x  0.364
2010 Hajszan T, Szigeti-Buck K, Sallam NL, Bober J, Parducz A, Maclusky NJ, Leranth C, Duman RS. Effects of estradiol on learned helplessness and associated remodeling of hippocampal spine synapses in female rats. Biological Psychiatry. 67: 168-74. PMID 19811775 DOI: 10.1016/J.Biopsych.2009.08.017  0.409
2010 Banasr M, Chowdhury GM, Terwilliger R, Newton SS, Duman RS, Behar KL, Sanacora G. Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole. Molecular Psychiatry. 15: 501-11. PMID 18825147 DOI: 10.1038/mp.2008.106  0.423
2009 Duman RS. Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression. Dialogues in Clinical Neuroscience. 11: 239-55. PMID 19877493  0.314
2009 Su XW, Li XY, Banasr M, Duman RS. Eszopiclone and fluoxetine enhance the survival of newborn neurons in the adult rat hippocampus. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 1421-8. PMID 19775501 DOI: 10.1017/S1461145709990629  0.401
2009 Su XW, Li XY, Banasr M, Koo JW, Shahid M, Henry B, Duman RS. Chronic treatment with AMPA receptor potentiator Org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus. Psychopharmacology. 206: 215-22. PMID 19603152 DOI: 10.1007/S00213-009-1598-0  0.608
2009 Koo JW, Duman RS. Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Current Opinion in Investigational Drugs (London, England : 2000). 10: 664-71. PMID 19579172  0.548
2009 Greene J, Banasr M, Lee B, Warner-Schmidt J, Duman RS. Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2459-68. PMID 19553916 DOI: 10.1038/npp.2009.68  0.786
2009 Koo JW, Duman RS. Interleukin-1 receptor null mutant mice show decreased anxiety-like behavior and enhanced fear memory. Neuroscience Letters. 456: 39-43. PMID 19429130 DOI: 10.1016/j.neulet.2009.03.068  0.541
2009 Duman CH, Schlesinger L, Terwilliger R, Russell DS, Newton SS, Duman RS. Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise. Behavioural Brain Research. 198: 366-71. PMID 19056428 DOI: 10.1016/j.bbr.2008.11.016  0.396
2009 Hajszan T, Dow A, Warner-Schmidt JL, Szigeti-Buck K, Sallam NL, Parducz A, Leranth C, Duman RS. Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression. Biological Psychiatry. 65: 392-400. PMID 19006787 DOI: 10.1016/J.Biopsych.2008.09.031  0.802
2009 Chepenik LG, Fredericks C, Papademetris X, Spencer L, Lacadie C, Wang F, Pittman B, Duncan JS, Staib LH, Duman RS, Gelernter J, Blumberg HP. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 944-51. PMID 18704093 DOI: 10.1038/Npp.2008.107  0.337
2009 Duman R. 33. Inhibition of IL-1 signaling blocks the anti-neurogenic and anhedonic actions of chronic stress Brain Behavior and Immunity. 23. DOI: 10.1016/J.Bbi.2009.06.038  0.312
2008 Schmidt HD, Banasr M, Duman RS. Future Antidepressant Targets: Neurotrophic Factors and Related Signaling Cascades. Drug Discovery Today. Therapeutic Strategies. 5: 151-156. PMID 19802372 DOI: 10.1016/j.ddstr.2008.10.003  0.448
2008 Lee AS, Duman RS, Pittenger C. A double dissociation revealing bidirectional competition between striatum and hippocampus during learning. Proceedings of the National Academy of Sciences of the United States of America. 105: 17163-8. PMID 18955704 DOI: 10.1073/Pnas.0807749105  0.559
2008 Banasr M, Duman RS. Keeping 'trk' of antidepressant actions. Neuron. 59: 349-51. PMID 18701059 DOI: 10.1016/j.neuron.2008.07.028  0.414
2008 Segi-Nishida E, Warner-Schmidt JL, Duman RS. Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 105: 11352-7. PMID 18682560 DOI: 10.1073/pnas.0710858105  0.795
2008 Banasr M, Duman RS. Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors. Biological Psychiatry. 64: 863-70. PMID 18639237 DOI: 10.1016/j.biopsych.2008.06.008  0.442
2008 Valentine G, Dow A, Banasr M, Pittman B, Duman R. Differential effects of chronic antidepressant treatment on shuttle box escape deficits induced by uncontrollable stress. Psychopharmacology. 200: 585-96. PMID 18604599 DOI: 10.1007/s00213-008-1239-z  0.792
2008 Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biological Psychiatry. 64: 527-32. PMID 18571629 DOI: 10.1016/J.Biopsych.2008.05.005  0.389
2008 Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nature Medicine. 14: 681-7. PMID 18516051 DOI: 10.1038/Nm1781  0.549
2008 Suda S, Segi-Nishida E, Newton SS, Duman RS. A postpartum model in rat: behavioral and gene expression changes induced by ovarian steroid deprivation. Biological Psychiatry. 64: 311-9. PMID 18471802 DOI: 10.1016/j.biopsych.2008.03.029  0.735
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, ... ... Duman RS, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005  0.62
2008 Warner-Schmidt JL, Madsen TM, Duman RS. Electroconvulsive seizure restores neurogenesis and hippocampus-dependent fear memory after disruption by irradiation. The European Journal of Neuroscience. 27: 1485-93. PMID 18336568 DOI: 10.1111/j.1460-9568.2008.06118.x  0.724
2008 Duman CH, Schlesinger L, Russell DS, Duman RS. Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Research. 1199: 148-58. PMID 18267317 DOI: 10.1016/j.brainres.2007.12.047  0.315
2008 Koo JW, Duman RS. IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proceedings of the National Academy of Sciences of the United States of America. 105: 751-6. PMID 18178625 DOI: 10.1073/pnas.0708092105  0.578
2008 Warner-Schmidt JL, Duman RS. VEGF as a potential target for therapeutic intervention in depression. Current Opinion in Pharmacology. 8: 14-9. PMID 18061540 DOI: 10.1016/j.coph.2007.10.013  0.733
2008 Tanis KQ, Duman RS, Newton SS. CREB binding and activity in brain: regional specificity and induction by electroconvulsive seizure. Biological Psychiatry. 63: 710-20. PMID 17936724 DOI: 10.1016/J.Biopsych.2007.08.003  0.394
2008 Gourley SL, Wu FJ, Kiraly DD, Ploski JE, Kedves AT, Duman RS, Taylor JR. Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression. Biological Psychiatry. 63: 353-9. PMID 17889834 DOI: 10.1016/j.biopsych.2007.07.016  0.463
2008 Pittenger C, Duman RS. Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 88-109. PMID 17851537 DOI: 10.1038/sj.npp.1301574  0.668
2008 Kosten TA, Galloway MP, Duman RS, Russell DS, D'Sa C. Repeated unpredictable stress and antidepressants differentially regulate expression of the bcl-2 family of apoptotic genes in rat cortical, hippocampal, and limbic brain structures. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1545-58. PMID 17700647 DOI: 10.1038/Sj.Npp.1301527  0.823
2008 Sahay A, Hen R, Duman RS. 23 Hippocampal Neurogenesis: Depression and Antidepressant Responses Cold Spring Harbor Monograph Archive. 52: 483-501. DOI: 10.1101/087969784.52.483  0.431
2008 Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. O4-02-06: Blocking Tgf-β-smad 2/3 innate immune signaling mitigates Alzheimer-like pathology in transgenic mice Alzheimer's & Dementia. 4: T187-T188. DOI: 10.1016/J.Jalz.2008.05.514  0.522
2008 Beech RD, Duman RS. The Role of Transcription Factors in the Biology of Depression Biology of Depression: From Novel Insights to Therapeutic Strategies. 823-854. DOI: 10.1002/9783527619672.ch33  0.554
2007 Hunsberger JG, Newton SS, Bennett AH, Duman CH, Russell DS, Salton SR, Duman RS. Antidepressant actions of the exercise-regulated gene VGF. Nature Medicine. 13: 1476-82. PMID 18059283 DOI: 10.1038/Nm1669  0.722
2007 Kang HJ, Adams DH, Simen A, Simen BB, Rajkowska G, Stockmeier CA, Overholser JC, Meltzer HY, Jurjus GJ, Konick LC, Newton SS, Duman RS. Gene expression profiling in postmortem prefrontal cortex of major depressive disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13329-40. PMID 18045927 DOI: 10.1523/Jneurosci.4083-07.2007  0.744
2007 Banasr M, Duman RS. Regulation of neurogenesis and gliogenesis by stress and antidepressant treatment. Cns & Neurological Disorders Drug Targets. 6: 311-20. PMID 18045159 DOI: 10.2174/187152707783220929  0.453
2007 Tanis KQ, Duman RS. Intracellular signaling pathways pave roads to recovery for mood disorders. Annals of Medicine. 39: 531-44. PMID 17852035 DOI: 10.1080/07853890701483270  0.396
2007 Duman RS. A silver bullet for the treatment of depression? Neuron. 55: 679-81. PMID 17785173 DOI: 10.1016/j.neuron.2007.08.011  0.361
2007 Schmidt HD, Duman RS. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behavioural Pharmacology. 18: 391-418. PMID 17762509 DOI: 10.1097/FBP.0b013e3282ee2aa8  0.49
2007 Newton SS, Duman RS. Neurogenic actions of atypical antipsychotic drugs and therapeutic implications. Cns Drugs. 21: 715-25. PMID 17696572 DOI: 10.2165/00023210-200721090-00002  0.379
2007 Banasr M, Valentine GW, Li XY, Gourley SL, Taylor JR, Duman RS. Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat. Biological Psychiatry. 62: 496-504. PMID 17585885 DOI: 10.1016/J.Biopsych.2007.02.006  0.451
2007 Tanis KQ, Newton SS, Duman RS. Targeting neurotrophic/growth factor expression and signaling for antidepressant drug development. Cns & Neurological Disorders Drug Targets. 6: 151-60. PMID 17430152 DOI: 10.2174/187152707780363276  0.453
2007 Warner-Schmidt JL, Duman RS. VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proceedings of the National Academy of Sciences of the United States of America. 104: 4647-52. PMID 17360578 DOI: 10.1073/pnas.0610282104  0.732
2007 Nair A, Vadodaria KC, Banerjee SB, Benekareddy M, Dias BG, Duman RS, Vaidya VA. Stressor-specific regulation of distinct brain-derived neurotrophic factor transcripts and cyclic AMP response element-binding protein expression in the postnatal and adult rat hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1504-19. PMID 17164818 DOI: 10.1038/Sj.Npp.1301276  0.814
2007 Fujita M, Imaizumi M, D'Sa C, Zoghbi SS, Crescenzo MS, Hong J, Musachio JL, Gee AD, Seidel J, Green MV, Pike VW, Duman RS, Innis RB. In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration. Synapse (New York, N.Y.). 61: 78-86. PMID 17117418 DOI: 10.1002/syn.20347  0.737
2007 Duman CH, Schlesinger L, Kodama M, Russell DS, Duman RS. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biological Psychiatry. 61: 661-70. PMID 16945347 DOI: 10.1016/j.biopsych.2006.05.047  0.447
2006 Ploski JE, Newton SS, Duman RS. Electroconvulsive seizure-induced gene expression profile of the hippocampus dentate gyrus granule cell layer. Journal of Neurochemistry. 99: 1122-32. PMID 17081142 DOI: 10.1111/j.1471-4159.2006.04156.x  0.386
2006 Newton SS, Girgenti MJ, Collier EF, Duman RS. Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. The European Journal of Neuroscience. 24: 819-28. PMID 16930411 DOI: 10.1111/j.1460-9568.2006.04958.x  0.391
2006 Newton SS, Duman RS. Chromatin remodeling: a novel mechanism of psychotropic drug action. Molecular Pharmacology. 70: 440-3. PMID 16728645 DOI: 10.1124/mol.106.027078  0.303
2006 Duman RS, Monteggia LM. A neurotrophic model for stress-related mood disorders. Biological Psychiatry. 59: 1116-27. PMID 16631126 DOI: 10.1016/J.Biopsych.2006.02.013  0.486
2006 Lee Y, Duman RS, Marek GJ. The mGlu2/3 receptor agonist LY354740 suppresses immobilization stress-induced increase in rat prefrontal cortical BDNF mRNA expression. Neuroscience Letters. 398: 328-32. PMID 16469447 DOI: 10.1016/j.neulet.2006.01.021  0.428
2006 Simen BB, Duman CH, Simen AA, Duman RS. TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting. Biological Psychiatry. 59: 775-85. PMID 16458261 DOI: 10.1016/j.biopsych.2005.10.013  0.4
2006 Warner-Schmidt JL, Duman RS. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus. 16: 239-49. PMID 16425236 DOI: 10.1002/hipo.20156  0.774
2005 Duman RS. Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism. Neurobiology of Aging. 26: 88-93. PMID 16226350 DOI: 10.1016/j.neurobiolaging.2005.08.018  0.422
2005 D'Sa C, Eisch AJ, Bolger GB, Duman RS. Differential expression and regulation of the cAMP-selective phosphodiesterase type 4A splice variants in rat brain by chronic antidepressant administration. The European Journal of Neuroscience. 22: 1463-75. PMID 16190900 DOI: 10.1111/j.1460-9568.2005.04321.x  0.767
2005 Hunsberger JG, Bennett AH, Selvanayagam E, Duman RS, Newton SS. Gene profiling the response to kainic acid induced seizures. Brain Research. Molecular Brain Research. 141: 95-112. PMID 16165245 DOI: 10.1016/J.Molbrainres.2005.08.005  0.723
2005 Carlezon WA, Duman RS, Nestler EJ. The many faces of CREB. Trends in Neurosciences. 28: 436-45. PMID 15982754 DOI: 10.1016/j.tins.2005.06.005  0.728
2005 Dow AL, Russell DS, Duman RS. Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4908-16. PMID 15901772 DOI: 10.1523/JNEUROSCI.5155-04.2005  0.838
2005 Hsu R, Taylor JR, Newton SS, Alvaro JD, Haile C, Han G, Hruby VJ, Nestler EJ, Duman RS. Blockade of melanocortin transmission inhibits cocaine reward. The European Journal of Neuroscience. 21: 2233-42. PMID 15869520 DOI: 10.1111/J.1460-9568.2005.04038.X  0.674
2005 Kodama M, Russell DS, Duman RS. Electroconvulsive seizures increase the expression of MAP kinase phosphatases in limbic regions of rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 360-71. PMID 15496935 DOI: 10.1038/sj.npp.1300588  0.38
2005 Madsen TM, Yeh DD, Valentine GW, Duman RS. Electroconvulsive seizure treatment increases cell proliferation in rat frontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 27-34. PMID 15383831 DOI: 10.1038/sj.npp.1300565  0.41
2005 Duman RS, Adams DH, Simen BB. Chapter 5.3 Transcription factors as modulators of stress responsivity Techniques in the Behavioral and Neural Sciences. 15: 679-698. DOI: 10.1016/S0921-0709(05)80036-7  0.397
2004 Duman RS. Neural plasticity: consequences of stress and actions of antidepressant treatment. Dialogues in Clinical Neuroscience. 6: 157-69. PMID 22034207  0.312
2004 Newton SS, Duman RS. Regulation of neurogenesis and angiogenesis in depression. Current Neurovascular Research. 1: 261-7. PMID 16181076 DOI: 10.2174/1567202043362388  0.416
2004 Krystal JH, Duman R. What's missing in posttraumatic stress disorder research? Studies of human postmortem tissue. Psychiatry. 67: 398-403. PMID 15801380 DOI: 10.1521/Psyc.67.4.398.56567  0.33
2004 Perrotti LI, Hadeishi Y, Ulery PG, Barrot M, Monteggia L, Duman RS, Nestler EJ. Induction of deltaFosB in reward-related brain structures after chronic stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10594-602. PMID 15564575 DOI: 10.1523/Jneurosci.2542-04.2004  0.623
2004 Kodama M, Fujioka T, Duman RS. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biological Psychiatry. 56: 570-80. PMID 15476686 DOI: 10.1016/j.biopsych.2004.07.008  0.436
2004 Newton SS, Collier EF, Bennett AH, Russell DS, Duman RS. Regulation of growth factor receptor bound 2 by electroconvulsive seizure. Brain Research. Molecular Brain Research. 129: 185-8. PMID 15469895 DOI: 10.1016/j.molbrainres.2004.06.032  0.407
2004 Sakai N, Tsubokawa H, Matsuzaki M, Kajimoto T, Takahashi E, Ren Y, Ohmori S, Shirai Y, Matsubayashi H, Chen J, Duman RS, Kasai H, Saito N. Propagation of gammaPKC translocation along the dendrites of Purkinje cell in gammaPKC-GFP transgenic mice. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 945-57. PMID 15461665 DOI: 10.1111/J.1365-2443.2004.00779.X  0.361
2004 Shirayama Y, Ishida H, Iwata M, Hazama GI, Kawahara R, Duman RS. Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects. Journal of Neurochemistry. 90: 1258-68. PMID 15312181 DOI: 10.1111/j.1471-4159.2004.02589.x  0.429
2004 Wallace TL, Stellitano KE, Neve RL, Duman RS. Effects of cyclic adenosine monophosphate response element binding protein overexpression in the basolateral amygdala on behavioral models of depression and anxiety. Biological Psychiatry. 56: 151-60. PMID 15271583 DOI: 10.1016/j.biopsych.2004.04.010  0.421
2004 Duman RS. Depression: a case of neuronal life and death? Biological Psychiatry. 56: 140-5. PMID 15271581 DOI: 10.1016/j.biopsych.2004.02.033  0.459
2004 Beech RD, Cleary MA, Treloar HB, Eisch AJ, Harrist AV, Zhong W, Greer CA, Duman RS, Picciotto MR. Nestin promoter/enhancer directs transgene expression to precursors of adult generated periglomerular neurons. The Journal of Comparative Neurology. 475: 128-41. PMID 15176089 DOI: 10.1002/Cne.20179  0.586
2004 Duman RS. Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Medicine. 5: 11-25. PMID 15001809 DOI: 10.1385/NMM:5:1:011  0.478
2004 Fujioka T, Fujioka A, Duman RS. Activation of cAMP signaling facilitates the morphological maturation of newborn neurons in adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 319-28. PMID 14724230 DOI: 10.1523/JNEUROSCI.1065.03.2004  0.381
2004 Chen J, Newton SS, Zeng L, Adams DH, Dow AL, Madsen TM, Nestler EJ, Duman RS. Downregulation of the CCAAT-enhancer binding protein beta in deltaFosB transgenic mice and by electroconvulsive seizures. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 23-31. PMID 14532910 DOI: 10.1038/sj.npp.1300289  0.814
2003 Newton SS, Collier EF, Hunsberger J, Adams D, Terwilliger R, Selvanayagam E, Duman RS. Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10841-51. PMID 14645477 DOI: 10.1523/Jneurosci.23-34-10841.2003  0.726
2003 Madsen TM, Newton SS, Eaton ME, Russell DS, Duman RS. Chronic electroconvulsive seizure up-regulates beta-catenin expression in rat hippocampus: role in adult neurogenesis. Biological Psychiatry. 54: 1006-14. PMID 14625142 DOI: 10.1016/S0006-3223(03)00700-5  0.32
2003 Tolbert LM, Russell DS, Duman RS. Norepinephrine activates extracellular-regulated kinase in cortical neurons. Biological Psychiatry. 54: 983-93. PMID 14625140 DOI: 10.1016/S0006-3223(03)00346-9  0.325
2003 Wu M, Newton SS, Atkins JB, Xu C, Duman RS, Alreja M. Acetylcholinesterase inhibitors activate septohippocampal GABAergic neurons via muscarinic but not nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 307: 535-43. PMID 12966162 DOI: 10.1124/jpet.103.052514  0.358
2003 Sheehan TP, Neve RL, Duman RS, Russell DS. Antidepressant effect of the calcium-activated tyrosine kinase Pyk2 in the lateral septum. Biological Psychiatry. 54: 540-51. PMID 12946883 DOI: 10.1016/S0006-3223(02)01815-2  0.485
2003 Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, Weisstaub N, Lee J, Duman R, Arancio O, Belzung C, Hen R. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (New York, N.Y.). 301: 805-9. PMID 12907793 DOI: 10.1126/Science.1083328  0.42
2003 Dias BG, Banerjee SB, Duman RS, Vaidya VA. Differential regulation of brain derived neurotrophic factor transcripts by antidepressant treatments in the adult rat brain. Neuropharmacology. 45: 553-63. PMID 12907316 DOI: 10.1016/S0028-3908(03)00198-9  0.809
2003 Cavus I, Duman RS. Influence of estradiol, stress, and 5-HT2A agonist treatment on brain-derived neurotrophic factor expression in female rats. Biological Psychiatry. 54: 59-69. PMID 12842309 DOI: 10.1016/S0006-3223(03)00236-1  0.421
2003 Malberg JE, Duman RS. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1562-71. PMID 12838272 DOI: 10.1038/Sj.Npp.1300234  0.74
2003 Coyle JT, Duman RS. Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron. 38: 157-60. PMID 12718851 DOI: 10.1016/S0896-6273(03)00195-8  0.37
2003 Peakman MC, Colby C, Perrotti LI, Tekumalla P, Carle T, Ulery P, Chao J, Duman C, Steffen C, Monteggia L, Allen MR, Stock JL, Duman RS, McNeish JD, Barrot M, et al. Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain Research. 970: 73-86. PMID 12706249 DOI: 10.1016/S0006-8993(03)02230-3  0.591
2003 Alvaro JD, Taylor JR, Duman RS. Molecular and behavioral interactions between central melanocortins and cocaine. The Journal of Pharmacology and Experimental Therapeutics. 304: 391-9. PMID 12490616 DOI: 10.1124/jpet.102.040311  0.302
2002 Thome J, Henn FA, Duman RS. Cyclic AMP response element-binding protein and depression. Expert Review of Neurotherapeutics. 2: 347-54. PMID 19810866 DOI: 10.1586/14737175.2.3.347  0.319
2002 Duman RS. Structural alterations in depression: cellular mechanisms underlying pathology and treatment of mood disorders. Cns Spectrums. 7: 140-2, 144-7. PMID 15220856 DOI: 10.1017/S1092852900017454  0.432
2002 Duman RS. Pathophysiology of depression: the concept of synaptic plasticity. European Psychiatry : the Journal of the Association of European Psychiatrists. 17: 306-10. PMID 15177086 DOI: 10.1016/S0924-9338(02)00654-5  0.315
2002 Newton SS, Thome J, Wallace TL, Shirayama Y, Schlesinger L, Sakai N, Chen J, Neve R, Nestler EJ, Duman RS. Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10883-90. PMID 12486182 DOI: 10.1523/Jneurosci.22-24-10883.2002  0.636
2002 Nakagawa S, Kim JE, Lee R, Chen J, Fujioka T, Malberg J, Tsuji S, Duman RS. Localization of phosphorylated cAMP response element-binding protein in immature neurons of adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9868-76. PMID 12427843 DOI: 10.1523/Jneurosci.22-22-09868.2002  0.735
2002 Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1  0.544
2002 Thome J, Duman RS, Henn FA. [Molecular aspects of antidepressive therapy. Transsynaptic effects on signal transduction, gene expression and neuronal plasticity]. Der Nervenarzt. 73: 595-9. PMID 12212521 DOI: 10.1007/S00115-002-1276-5  0.447
2002 D'Sa C, Duman RS. Antidepressants and neuroplasticity. Bipolar Disorders. 4: 183-94. PMID 12180273 DOI: 10.1034/j.1399-5618.2002.01203.x  0.775
2002 Newton SS, Dow A, Terwilliger R, Duman R. A simplified method for combined immunohistochemistry and in-situ hybridization in fresh-frozen, cryocut mouse brain sections Brain Research Protocols. 9: 214-219. PMID 12113781 DOI: 10.1016/S1385-299X(02)00148-4  0.788
2002 Rasmusson AM, Shi L, Duman R. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology. 27: 133-142. PMID 12093587 DOI: 10.1016/S0893-133X(02)00286-5  0.379
2002 D'Sa C, Tolbert LM, Conti M, Duman RS. Regulation of cAMP-specific phosphodiesterases type 4B and 4D (PDE4) splice variants by cAMP signaling in primary cortical neurons. Journal of Neurochemistry. 81: 745-57. PMID 12065634 DOI: 10.1046/J.1471-4159.2002.00878.X  0.74
2002 Duman RS. Genetics of childhood disorders: XXXIX. Stem cell research, part 3: Regulation of neurogenesis by stress and antidepressant treatment. Journal of the American Academy of Child and Adolescent Psychiatry. 41: 745-8. PMID 12049451 DOI: 10.1097/00004583-200206000-00016  0.356
2002 Sakai N, Thome J, Newton SS, Chen J, Kelz MB, Steffen C, Nestler EJ, Duman RS. Inducible and brain region-specific CREB transgenic mice. Molecular Pharmacology. 61: 1453-64. PMID 12021407 DOI: 10.1124/Mol.61.6.1453  0.602
2002 Duman RS. Synaptic plasticity and mood disorders. Molecular Psychiatry. 7: S29-34. PMID 11986993 DOI: 10.1038/sj.mp.4001016  0.398
2002 Nakagawa S, Kim JE, Lee R, Malberg JE, Chen J, Steffen C, Zhang YJ, Nestler EJ, Duman RS. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3673-82. PMID 11978843 DOI: 10.1523/Jneurosci.22-09-03673.2002  0.789
2002 Shaw-Lutchman TZ, Barrot M, Wallace T, Gilden L, Zachariou V, Impey S, Duman RS, Storm D, Nestler EJ. Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3663-72. PMID 11978842 DOI: 10.1523/Jneurosci.22-09-03663.2002  0.599
2002 Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3251-61. PMID 11943826 DOI: 10.1523/Jneurosci.22-08-03251.2002  0.425
2001 Duman RS, Nakagawa S, Malberg J. Regulation of adult neurogenesis by antidepressant treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 836-44. PMID 11750177 DOI: 10.1016/S0893-133X(01)00358-X  0.76
2001 Thome J, Pesold B, Baader M, Hu M, Gewirtz JC, Duman RS, Henn FA. Stress differentially regulates synaptophysin and synaptotagmin expression in hippocampus. Biological Psychiatry. 50: 809-12. PMID 11720700 DOI: 10.1016/S0006-3223(01)01229-X  0.414
2001 Vaidya VA, Duman RS. Depresssion--emerging insights from neurobiology. British Medical Bulletin. 57: 61-79. PMID 11719924 DOI: 10.1093/bmb/57.1.61  0.794
2001 Chen AC, Shirayama Y, Shin KH, Neve RL, Duman RS. Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect. Biological Psychiatry. 49: 753-62. PMID 11331083 DOI: 10.1016/S0006-3223(00)01114-8  0.412
2001 Chen AC, Shin KH, Duman RS, Sanacora G. ECS-Induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment. The Journal of Ect. 17: 27-32. PMID 11281511 DOI: 10.1097/00124509-200103000-00006  0.411
2001 Chen AC, Eisch AJ, Sakai N, Takahashi M, Nestler EJ, Duman RS. Regulation of GFRalpha-1 and GFRalpha-2 mRNAs in rat brain by electroconvulsive seizure. Synapse (New York, N.Y.). 39: 42-50. PMID 11071708 DOI: 10.1002/1098-2396(20010101)39:1<42::AID-SYN6>3.0.CO;2-#  0.618
2001 Duman RS, Thome J. CREB and chronic antidepressant treatments European Neuropsychopharmacology. 11. DOI: 10.1016/S0924-977X(01)80119-X  0.329
2000 Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9104-10. PMID 11124987 DOI: 10.1523/Jneurosci.20-24-09104.2000  0.811
2000 Duman RS, Malberg J, Nakagawa S, D'Sa C. Neuronal plasticity and survival in mood disorders. Biological Psychiatry. 48: 732-9. PMID 11063970 DOI: 10.1016/S0006-3223(00)00935-5  0.812
2000 Thome J, Sakai N, Shin K, Steffen C, Zhang YJ, Impey S, Storm D, Duman RS. cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4030-6. PMID 10818138 DOI: 10.1523/Jneurosci.20-11-04030.2000  0.42
2000 Fujimaki K, Morinobu S, Duman RS. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 42-51. PMID 10633490 DOI: 10.1016/S0893-133X(99)00084-6  0.37
2000 Iredale PA, Alvaro JD, Lee Y, Terwilliger R, Chen YL, Duman RS. Role of corticotropin-releasing factor receptor-1 in opiate withdrawal. Journal of Neurochemistry. 74: 199-208. PMID 10617121 DOI: 10.1046/j.1471-4159.2000.0740199.x  0.348
2000 Vaidya VA, Terwilliger RZ, Duman RS. Alterations in heavy and light neurofilament proteins in hippocampus following chronic ECS administration. Synapse (New York, N.Y.). 35: 137-43. PMID 10611639 DOI: 10.1002/(SICI)1098-2396(200002)35:2<137::AID-SYN6>3.0.CO;2-F  0.768
1999 Duman RS, Malberg J, Thome J. Neural plasticity to stress and antidepressant treatment. Biological Psychiatry. 46: 1181-91. PMID 10560024 DOI: 10.1016/S0006-3223(99)00177-8  0.774
1999 Sakai N, Tolbert LM, Duman RS. Identification and functional analysis of novel cAMP response element binding protein splice variants lacking the basic/leucine zipper domain. Molecular Pharmacology. 56: 917-25. PMID 10531395 DOI: 10.1124/Mol.56.5.917  0.321
1999 Kelz MB, Chen J, Carlezon WA, Whisler K, Gilden L, Beckmann AM, Steffen C, Zhang YJ, Marotti L, Self DW, Tkatch T, Baranauskas G, Surmeier DJ, Neve RL, Duman RS, et al. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature. 401: 272-6. PMID 10499584 DOI: 10.1038/45790  0.681
1999 Nibuya M, Takahashi M, Russell DS, Duman RS. Repeated stress increases catalytic TrkB mRNA in rat hippocampus. Neuroscience Letters. 267: 81-4. PMID 10400217 DOI: 10.1016/S0304-3940(99)00335-3  0.377
1999 Ni YG, Gold SJ, Iredale PA, Terwilliger RZ, Duman RS, Nestler EJ. Region-specific regulation of RGS4 (Regulator of G-protein-signaling protein type 4) in brain by stress and glucocorticoids: in vivo and in vitro studies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3674-80. PMID 10233999 DOI: 10.1523/Jneurosci.19-10-03674.1999  0.628
1999 Morinobu S, Fujimaki K, Okuyama N, Takahashi M, Duman RS. Stimulation of adenylyl cyclase and induction of brain-derived neurotrophic factor and TrkB mRNA by NKH477, a novel and potent forskolin derivative. Journal of Neurochemistry. 72: 2198-205. PMID 10217303 DOI: 10.1046/j.1471-4159.1999.0722198.x  0.375
1999 Vaidya VA, Terwilliger RM, Duman RS. Role of 5-HT2A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus. Neuroscience Letters. 262: 1-4. PMID 10076858 DOI: 10.1016/S0304-3940(99)00006-3  0.776
1999 Vaidya VA, Siuciak JA, Du F, Duman RS. Hippocampal mossy fiber sprouting induced by chronic electroconvulsive seizures. Neuroscience. 89: 157-66. PMID 10051225 DOI: 10.1016/S0306-4522(98)00289-9  0.761
1999 Duman RS. Neuropharmacology in the next millennium: promise for breakthrough discoveries. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 97-8. PMID 9885789 DOI: 10.1016/S0893-133X(98)00105-5  0.348
1999 Takahashi M, Terwilliger R, Lane C, Mezes PS, Conti M, Duman RS. Chronic antidepressant administration increases the expression of cAMP-specific phosphodiesterase 4A and 4B isoforms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 610-8. PMID 9880581 DOI: 10.1523/Jneurosci.19-02-00610.1999  0.452
1998 Carlezon WA, Thome J, Olson VG, Lane-Ladd SB, Brodkin ES, Hiroi N, Duman RS, Neve RL, Nestler EJ. Regulation of cocaine reward by CREB. Science (New York, N.Y.). 282: 2272-5. PMID 9856954 DOI: 10.1126/Science.282.5397.2272  0.668
1998 Duman RS, Vaidya VA. Molecular and cellular actions of chronic electroconvulsive seizures. The Journal of Ect. 14: 181-93. PMID 9773357 DOI: 10.1097/00124509-199809000-00004  0.788
1998 Duman RS. Novel therapeutic approaches beyond the serotonin receptor. Biological Psychiatry. 44: 324-35. PMID 9755354 DOI: 10.1016/S0006-3223(98)00031-6  0.479
1998 Chen J, Kelz MB, Zeng G, Sakai N, Steffen C, Shockett PE, Picciotto MR, Duman RS, Nestler EJ. Transgenic animals with inducible, targeted gene expression in brain. Molecular Pharmacology. 54: 495-503. PMID 9730908 DOI: 10.1124/Mol.54.3.495  0.591
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6952-62. PMID 9712664 DOI: 10.1523/Jneurosci.18-17-06952.1998  0.806
1998 Li Z, Vaidya VA, Alvaro JD, Iredale PA, Hsu R, Hoffman G, Fitzgerald L, Curran PK, Machida CA, Fishman PH, Duman RS. Protein kinase C-mediated down-regulation of beta1-adrenergic receptor gene expression in rat C6 glioma cells. Molecular Pharmacology. 54: 14-21. PMID 9658185 DOI: 10.1124/Mol.54.1.14  0.79
1997 Iredale PA, Bundey R, Duman RS. Phorbol ester and calcium regulation of corticotrophin-releasing factor receptor 1 expression in a neuronal cell line. Journal of Neurochemistry. 69: 1912-9. PMID 9349535 DOI: 10.1046/J.1471-4159.1997.69051912.X  0.303
1997 Charlton ME, Williams AS, Fogliano M, Sweetnam PM, Duman RS. The isolation and characterization of a novel G protein-coupled receptor regulated by immunologic challenge. Brain Research. 764: 141-8. PMID 9295203 DOI: 10.1016/S0006-8993(97)00438-1  0.336
1997 Duman RS, Heninger GR, Nestler EJ. A molecular and cellular theory of depression. Archives of General Psychiatry. 54: 597-606. PMID 9236543 DOI: 10.1001/Archpsyc.1997.01830190015002  0.684
1997 Iredale PA, Charlton ME, Alvaro JD, Duman RS. Regulation of receptor expression. Analysis of receptor mRNA and gene transcription. Methods in Molecular Biology (Clifton, N.J.). 83: 251-72. PMID 9210152 DOI: 10.1385/0-89603-495-X:251  0.314
1997 Alvaro JD, Tatro JB, Duman RS. Melanocortins and opiate addiction. Life Sciences. 61: 1-9. PMID 9200663 DOI: 10.1016/S0024-3205(97)00029-5  0.322
1997 Iredale PA, Duman RS. Glucocorticoid regulation of corticotropin-releasing factor1 receptor expression in pituitary-derived AtT-20 cells. Molecular Pharmacology. 51: 794-9. PMID 9145917 DOI: 10.1124/Mol.51.5.794  0.324
1997 Morinobu S, Strausbaugh H, Terwilliger R, Duman RS. Regulation of c-Fos and NGF1-A by antidepressant treatments. Synapse (New York, N.Y.). 25: 313-20. PMID 9097389 DOI: 10.1002/(SICI)1098-2396(199704)25:4<313::AID-SYN1>3.0.CO;2-D  0.386
1997 Huang QH, Entwistle ML, Alvaro JD, Duman RS, Hruby VJ, Tatro JB. Antipyretic role of endogenous melanocortins mediated by central melanocortin receptors during endotoxin-induced fever. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3343-51. PMID 9096167 DOI: 10.1523/Jneurosci.17-09-03343.1997  0.309
1997 Vaidya VA, Marek GJ, Aghajanian GK, Duman RS. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2785-95. PMID 9092600 DOI: 10.1523/Jneurosci.17-08-02785.1997  0.766
1997 Malison RT, Price LH, Nestler EJ, Heninger GR, Duman RS. Efficacy of papaverine addition for treatment-refractory major depression. The American Journal of Psychiatry. 154: 579-80. PMID 9090353 DOI: 10.1176/AJP.154.4.579  0.547
1997 Duman RS, Nestler EJ. Molecular biology, III. Tracking DNA: the Southern blot. The American Journal of Psychiatry. 154: 3. PMID 8988951  0.437
1997 Charlton ME, Sweetnam PM, Fitzgerald LW, Terwilliger RZ, Nestler EJ, Duman RS. Chronic ethanol administration regulates the expression of GABAA receptor alpha 1 and alpha 5 subunits in the ventral tegmental area and hippocampus. Journal of Neurochemistry. 68: 121-7. PMID 8978717 DOI: 10.1046/j.1471-4159.1997.68010121.x  0.581
1997 Duman RS. Signal-regulated transcription factors as targets for antidepressants Biological Psychiatry. 42: 274. DOI: 10.1016/S0006-3223(97)88055-9  0.308
1996 Iredale PA, Terwilliger R, Widnell KL, Nestler EJ, Duman RS. Differential regulation of corticotropin-releasing factor1 receptor expression by stress and agonist treatments in brain and cultured cells. Molecular Pharmacology. 50: 1103-10. PMID 8913341  0.566
1996 Deutch AY, Duman RS. The effects of antipsychotic drugs on Fos protein expression in the prefrontal cortex: cellular localization and pharmacological characterization. Neuroscience. 70: 377-89. PMID 8848147 DOI: 10.1016/0306-4522(95)00357-6  0.347
1996 Alvaro JD, Tatro JB, Quillan JM, Fogliano M, Eisenhard M, Lerner MR, Nestler EJ, Duman RS. Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction. Molecular Pharmacology. 50: 583-91. PMID 8794897  0.542
1996 Fitzgerald LR, Li Z, Machida CA, Fishman PH, Duman RS. Adrenergic regulation of ICER (inducible cyclic AMP early repressor) and beta1-adrenergic receptor gene expression in C6 glioma cells. Journal of Neurochemistry. 67: 490-7. PMID 8764572 DOI: 10.1046/j.1471-4159.1996.67020490.x  0.359
1996 Widnell KL, Chen JS, Iredale PA, Walker WH, Duman RS, Habener JF, Nestler EJ. Transcriptional regulation of CREB (cyclic AMP response element-binding protein) expression in CATH.a cells. Journal of Neurochemistry. 66: 1770-3. PMID 8627337 DOI: 10.1046/J.1471-4159.1996.66041770.X  0.587
1996 Nibuya M, Nestler EJ, Duman RS. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2365-72. PMID 8601816 DOI: 10.1523/Jneurosci.16-07-02365.1996  0.647
1996 Widnell KL, Self DW, Lane SB, Russell DS, Vaidya VA, Miserendino MJ, Rubin CS, Duman RS, Nestler EJ. Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 276: 306-15. PMID 8558448  0.799
1996 Fitzgerald LR, Vaidya VA, Terwilliger RZ, Duman RS. Electroconvulsive seizure increases the expression of CREM (cyclic AMP response element modulator) and ICER (inducible cyclic AMP early repressor) in rat brain. Journal of Neurochemistry. 66: 429-32. PMID 8522985 DOI: 10.1046/J.1471-4159.1996.66010429.X  0.766
1995 Ortiz J, Fitzgerald LW, Charlton M, Lane S, Trevisan L, Guitart X, Shoemaker W, Duman RS, Nestler EJ. Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Synapse (New York, N.Y.). 21: 289-98. PMID 8869159 DOI: 10.1002/syn.890210403  0.583
1995 Lee MJ, Saijoh K, Nestler EJ, Duman RS, Sumino K. Regional differences in expression of osteonectin mRNA after administration of cadmium to rats. Archives of Toxicology. 69: 590-5. PMID 8660135 DOI: 10.1007/s002040050218  0.536
1995 Fitzgerald LW, Charlton ME, Duman RS, Nestler EJ. Regulation of neuronal nitric oxide synthase by chronic ethanol ingestion. Synapse (New York, N.Y.). 21: 93-5. PMID 8525467 DOI: 10.1002/syn.890210113  0.547
1995 Rosin DL, Melia K, Knorr AM, Nestler EJ, Roth RH, Duman RS. Chronic imipramine administration alters the activity and phosphorylation state of tyrosine hydroxylase in dopaminergic regions of rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12: 113-21. PMID 7779239 DOI: 10.1016/0893-133X(94)00066-9  0.599
1995 Nestler EJ, Terwilliger RZ, Duman RS. Regulation of endogenous ADP-ribosylation by acute and chronic lithium in rat brain. Journal of Neurochemistry. 64: 2319-24. PMID 7722518 DOI: 10.1046/J.1471-4159.1995.64052319.X  0.61
1995 Hosoda K, Fitzgerald LR, Vaidya VA, Feussner GK, Fishman PH, Duman RS. Regulation of beta 2-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells: effects of agonist, forskolin, and protein synthesis inhibition. Molecular Pharmacology. 48: 206-11. PMID 7651353  0.713
1995 Morinobu S, Nibuya M, Duman RS. Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat frontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12: 221-8. PMID 7612155 DOI: 10.1016/0893-133X(94)00067-A  0.411
1995 Deutch AY, Ongür D, Duman RS. Antipsychotic drugs induce Fos protein in the thalamic paraventricular nucleus: a novel locus of antipsychotic drug action. Neuroscience. 66: 337-46. PMID 7477876 DOI: 10.1016/0306-4522(94)00571-L  0.331
1995 Nibuya M, Morinobu S, Duman RS. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7539-47. PMID 7472505 DOI: 10.1523/Jneurosci.15-11-07539.1995  0.419
1995 Duman RS, Vaidya VA, Nibuya M, Morinobu S, Fitzgerald LR. Review : Stress, Antidepressant Treatments, and Neurotrophic Factors: Molecular and Cellular Mechanisms The Neuroscientist. 1: 351-360. DOI: 10.1177/107385849500100607  0.79
1994 Duman RS, Fishman PH, Tallman JF. Induction of beta 2-adrenergic receptor mRNA and ligand binding in HeLa cells. Journal of Receptor Research. 14: 1-10. PMID 8158578 DOI: 10.3109/10799899409066992  0.536
1994 Trevisan L, Fitzgerald LW, Brose N, Gasic GP, Heinemann SF, Duman RS, Nestler EJ. Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. Journal of Neurochemistry. 62: 1635-8. PMID 8133290 DOI: 10.1046/j.1471-4159.1994.62041635.x  0.585
1994 Hope BT, Kelz MB, Duman RS, Nestler EJ. Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4318-28. PMID 8027782 DOI: 10.1523/Jneurosci.14-07-04318.1994  0.597
1994 Duman RS, Heninger GR, Nestler EJ. Molecular psychiatry. Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity. The Journal of Nervous and Mental Disease. 182: 692-700. PMID 7989913 DOI: 10.1097/00005053-199412000-00003  0.617
1994 Hope BT, Nye HE, Kelz MB, Self DW, Iadarola MJ, Nakabeppu Y, Duman RS, Nestler EJ. Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron. 13: 1235-44. PMID 7946359 DOI: 10.1016/0896-6273(94)90061-2  0.582
1993 Xin W, Terwilliger RZ, Rimland J, Wong ML, Nestler EJ, Duman RS. Characterization and functional expression of a somatostatin receptor coupled to adenylyl cyclase. Molecular and Cellular Neurosciences. 4: 259-66. PMID 19912931 DOI: 10.1006/mcne.1993.1033  0.559
1993 Bergson C, Zhao H, Saijoh K, Duman RS, Nestler EJ. Ezrin and osteonectin, two proteins associated with cell shape and growth, are enriched in the locus coeruleus. Molecular and Cellular Neurosciences. 4: 64-73. PMID 19912909 DOI: 10.1006/mcne.1993.1008  0.6
1993 Hosoda K, Duman RS. Regulation of beta 1-adrenergic receptor mRNA and ligand binding by antidepressant treatments and norepinephrine depletion in rat frontal cortex. Journal of Neurochemistry. 60: 1335-43. PMID 8384247 DOI: 10.1111/J.1471-4159.1993.Tb03294.X  0.304
1993 Duman RS, Terwilliger RZ, Nestler EJ. Alterations in nitric oxide-stimulated endogenous ADP-ribosylation associated with long-term potentiation in rat hippocampus. Journal of Neurochemistry. 61: 1542-5. PMID 8377004 DOI: 10.1111/j.1471-4159.1993.tb13652.x  0.57
1993 Butler MO, Morinobu S, Duman RS. Chronic electroconvulsive seizures increase the expression of serotonin2 receptor mRNA in rat frontal cortex. Journal of Neurochemistry. 61: 1270-6. PMID 8376984 DOI: 10.1111/J.1471-4159.1993.Tb13618.X  0.34
1993 Vaccarino FM, Hayward MD, Le HN, Hartigan DJ, Duman RS, Nestler EJ. Induction of immediate early genes by cyclic AMP in primary cultures of neurons from rat cerebral cortex. Brain Research. Molecular Brain Research. 19: 76-82. PMID 8103187 DOI: 10.1016/0169-328X(93)90151-E  0.605
1992 Duman RS, Craig JS, Winston SM, Deutch AY, Hernandez TD. Amygdala kindling potentiates seizure-stimulated immediate-early gene expression in rat cerebral cortex. Journal of Neurochemistry. 59: 1753-60. PMID 1402920 DOI: 10.1111/J.1471-4159.1992.Tb11007.X  0.343
1992 Melia KR, Nestler EJ, Duman RS. Chronic imipramine treatment normalizes levels of tyrosine hydroxylase in the locus coeruleus of chronically stressed rats. Psychopharmacology. 108: 23-6. PMID 1357707 DOI: 10.1007/BF02245280  0.608
1992 Vaccarino FM, Hayward MD, Nestler EJ, Duman RS, Tallman JF. Differential induction of immediate early genes by excitatory amino acid receptor types in primary cultures of cortical and striatal neurons. Brain Research. Molecular Brain Research. 12: 233-41. PMID 1347632 DOI: 10.1016/0169-328X(92)90089-T  0.71
1992 Melia KR, Rasmussen K, Terwilliger RZ, Haycock JW, Nestler EJ, Duman RS. Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: effects of chronic stress and drug treatments. Journal of Neurochemistry. 58: 494-502. PMID 1345939 DOI: 10.1111/J.1471-4159.1992.Tb09748.X  0.623
1991 Colin SF, Chang HC, Mollner S, Pfeuffer T, Reed RR, Duman RS, Nestler EJ. Chronic lithium regulates the expression of adenylate cyclase and Gi-protein alpha subunit in rat cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 88: 10634-7. PMID 1720545 DOI: 10.1073/PNAS.88.23.10634  0.587
1991 Duman RS, Terwilliger RZ, Nestler EJ. Endogenous ADP-ribosylation in brain: initial characterization of substrate proteins. Journal of Neurochemistry. 57: 2124-32. PMID 1682421 DOI: 10.1111/j.1471-4159.1991.tb06431.x  0.564
1990 Duman RS, Winston SM, Clark JA, Nestler EJ. Corticosterone regulates the expression of ADP-ribosylation factor messenger RNA and protein in rat cerebral cortex. Journal of Neurochemistry. 55: 1813-6. PMID 2213026 DOI: 10.1111/j.1471-4159.1990.tb04974.x  0.619
1990 Garrett KM, Saito N, Duman RS, Abel MS, Ashton RA, Fujimori S, Beer B, Tallman JF, Vitek MP, Blume AJ. Differential expression of gamma-aminobutyric acidA receptor subunits. Molecular Pharmacology. 37: 652-7. PMID 2160058  0.544
1990 Nestler EJ, Terwilliger RZ, Walker JR, Sevarino KA, Duman RS. Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain. Journal of Neurochemistry. 55: 1079-82. PMID 2117048 DOI: 10.1111/j.1471-4159.1990.tb04602.x  0.571
1990 Winston SM, Hayward MD, Nestler EJ, Duman RS. Chronic electroconvulsive seizures down-regulate expression of the immediate-early genes c-fos and c-jun in rat cerebral cortex. Journal of Neurochemistry. 54: 1920-5. PMID 2110970 DOI: 10.1111/j.1471-4159.1990.tb04892.x  0.57
1990 Nestler EJ, McMahon A, Sabban EL, Tallman JF, Duman RS. Chronic antidepressant administration decreases the expression of tyrosine hydroxylase in the rat locus coeruleus. Proceedings of the National Academy of Sciences of the United States of America. 87: 7522-6. PMID 1977162 DOI: 10.1073/Pnas.87.19.7522  0.749
1990 Heninger C, Saito N, Tallman JF, Garrett KM, Vitek MP, Duman RS, Gallager DW. Effects of continuous diazepam administration on GABAA subunit mRNA in rat brain. Journal of Molecular Neuroscience : Mn. 2: 101-7. PMID 1964063 DOI: 10.1007/BF02876917  0.603
1990 Hayward MD, Duman RS, Nestler EJ. Induction of the c-fos proto-oncogene during opiate withdrawal in the locus coeruleus and other regions of rat brain. Brain Research. 525: 256-66. PMID 1701330 DOI: 10.1016/0006-8993(90)90872-9  0.614
1990 Nestler EJ, McMahon A, Sabban EL, Tallman JF, Duman RS. Chronic antidepressant administration decreases the expression of tyrosine hydroxylase in the rat locus coeruleus Proceedings of the National Academy of Sciences of the United States of America. 87: 7527-7531.  0.73
1989 Nestler EJ, Terwilliger RZ, Duman RS. Chronic antidepressant administration alters the subcellular distribution of cyclic AMP-dependent protein kinase in rat frontal cortex. Journal of Neurochemistry. 53: 1644-7. PMID 2795022 DOI: 10.1111/j.1471-4159.1989.tb08564.x  0.611
1989 Duman RS, Saito N, Tallman JF. Development of beta-adrenergic receptor and G protein messenger RNA in rat brain. Brain Research. Molecular Brain Research. 5: 289-96. PMID 2546000 DOI: 10.1016/0169-328X(89)90063-6  0.57
1989 Duman RS, Terwilliger RZ, Nestler EJ, Tallman JF. Sodium and potassium regulation of guanine nucleotide-stimulated adenylate cyclase in brain. Biochemical Pharmacology. 38: 1909-14. PMID 2545204 DOI: 10.1016/0006-2952(89)90488-7  0.692
1989 Duman RS, Strada SJ, Enna SJ. Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices. Brain Research. 477: 166-71. PMID 2539229 DOI: 10.1016/0006-8993(89)91404-2  0.49
1989 Saito N, Guitart X, Hayward M, Tallman JF, Duman RS, Nestler EJ. Corticosterone differentially regulates the expression of Gs alpha and Gi alpha messenger RNA and protein in rat cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 86: 3906-10. PMID 2498878 DOI: 10.1073/PNAS.86.10.3906  0.691
1989 Nestler EJ, Erdos JJ, Terwilliger R, Duman RS, Tallman JF. Regulation of G proteins by chronic morphine in the rat locus coeruleus. Brain Research. 476: 230-9. PMID 2495149 DOI: 10.1016/0006-8993(89)91243-2  0.721
1988 Garrett KM, Duman RS, Saito N, Blume AJ, Vitek MP, Tallman JF. Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor. Biochemical and Biophysical Research Communications. 156: 1039-45. PMID 2847710 DOI: 10.1016/S0006-291X(88)80949-5  0.567
1988 Duman RS, Tallman JF, Nestler EJ. Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus. The Journal of Pharmacology and Experimental Therapeutics. 246: 1033-9. PMID 2843624  0.58
1987 Zorn SH, Duman RS, Giachetti A, Micheletti R, Giraldo E, Krogsgaard-Larsen P, Enna SJ. (R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 242: 173-8. PMID 2886636  0.406
1987 Nomura S, Duman RS, Enna SJ. In vivo or in vitro exposure to imipramine reduces alpha 2-adrenoceptor-mediated inhibition of cyclic AMP production in rat brain cerebral cortical slices. Brain Research. 410: 195-8. PMID 2884021 DOI: 10.1016/S0006-8993(87)80046-X  0.472
1987 Duman RS, Sweetnam PM, Gallombardo PA, Tallman JF. Molecular biology of inhibitory amino acid receptors. Molecular Neurobiology. 1: 155-89. PMID 2855790 DOI: 10.1007/BF02935267  0.574
1987 Duman RS, Enna SJ. Modulation of receptor-mediated cyclic AMP production in brain. Neuropharmacology. 26: 981-6. PMID 2821437 DOI: 10.1016/0028-3908(87)90076-1  0.532
1986 Duman RS, Enna SJ. A procedure for measuring alpha 2-adrenergic receptor-mediated inhibition of cyclic AMP accumulation in rat brain slices. Brain Research. 384: 391-4. PMID 3022868 DOI: 10.1016/0006-8993(86)91179-0  0.427
1986 Duman RS, Karbon EW, Harrington C, Enna SJ. An examination of the involvement of phospholipases A2 and C in the alpha-adrenergic and gamma-aminobutyric acid receptor modulation of cyclic AMP accumulation in rat brain slices. Journal of Neurochemistry. 47: 800-10. PMID 2874192 DOI: 10.1111/J.1471-4159.1986.Tb00682.X  0.441
1985 Duman RS, Strada SJ, Enna SJ. Effect of imipramine and adrenocorticotropin administration on the rat brain norepinephrine-coupled cyclic nucleotide generating system: alterations in alpha and beta adrenergic components. The Journal of Pharmacology and Experimental Therapeutics. 234: 409-14. PMID 2991501  0.478
1984 Duman RS, Andree T, Kendall DA, Enna SJ. Effect of adrenocorticotropin administration on beta-adrenergic receptor adaptations in rat brain cerebral cortex. Journal of Neurochemistry. 42: 33-7. PMID 6315893  0.619
1984 Karbon EW, Duman RS, Enna SJ. GABAB receptors and norepinephrine-stimulated cAMP production in rat brain cortex. Brain Research. 306: 327-32. PMID 6087977 DOI: 10.1016/0006-8993(84)90382-2  0.485
1983 Enna SJ, Duman RS. beta-Adrenergic receptor regulation and antidepressants: the influence of adrenocorticotropin. Journal of Neural Transmission. 57: 297-307. PMID 6317800 DOI: 10.1007/BF01249000  0.498
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