Karen Gylys - Publications

Affiliations: 
Neuroscience University of California, Los Angeles, Los Angeles, CA 
Area:
Neurobiology Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Bilousova T, Elias C, Miyoshi E, Alam MP, Zhu C, Campagna J, Vadivel K, Jagodzinska B, Gylys K, John V. Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2. Biochemical and Biophysical Research Communications. PMID 29604274 DOI: 10.1016/j.bbrc.2018.03.209  0.32
2018 Ma QL, Teng E, Zuo X, Jones M, Teter B, Zhao EY, Zhu C, Bilousova T, Gylys KH, Apostolova LG, LaDu MJ, Hossain MA, Frautschy SA, Cole GM. Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease. Neurobiology of Disease. PMID 29501530 DOI: 10.1016/j.nbd.2018.02.014  0.32
2017 Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, ... Gylys KH, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 94: 278-293.e9. PMID 28426964 DOI: 10.1016/j.neuron.2017.03.042  0.32
2017 Gonzalez B, Abud EM, Abud AM, Poon WW, Gylys KH. Tau Spread, Apolipoprotein E, Inflammation, and More: Rapidly Evolving Basic Science in Alzheimer Disease. Neurologic Clinics. 35: 175-190. PMID 28410655 DOI: 10.1016/j.ncl.2017.01.001  0.32
2017 Gylys KH, Bilousova T. Flow Cytometry Analysis and Quantitative Characterization of Tau in Synaptosomes from Alzheimer's Disease Brains. Methods in Molecular Biology (Clifton, N.J.). 1523: 273-284. PMID 27975256 DOI: 10.1007/978-1-4939-6598-4_16  0.32
2016 Prieto GA, Trieu BH, Dang CT, Bilousova T, Gylys KH, Berchtold NC, Lynch G, Cotman CW. Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986924 DOI: 10.1523/JNEUROSCI.2774-16.2016  0.32
2016 Zhang L, Trushin S, Christensen TA, Bachmeier BV, Gateno B, Schroeder A, Yao J, Itoh K, Sesaki H, Poon WW, Gylys KH, Patterson ER, Parisi JE, Diaz Brinton R, Salisbury JL, et al. Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease. Scientific Reports. 6: 18725. PMID 26729583 DOI: 10.1038/srep18725  0.32
2016 Bilousova T, Miller CA, Poon WW, Vinters HV, Corrada M, Kawas C, Hayden EY, Teplow DB, Glabe C, Albay R, Cole GM, Teng E, Gylys KH. Synaptic Amyloid-β Oligomers Precede p-Tau and Differentiate High Pathology Control Cases. The American Journal of Pathology. 186: 185-98. PMID 26718979 DOI: 10.1016/j.ajpath.2015.09.018  0.32
2015 Hwang KS, Lazaris AS, Eastman JA, Teng E, Thompson PM, Gylys KH, Cole GM, Apostolova LG. Plasma BDNF levels associate with Pittsburgh compound B binding in the brain. Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring. 1: 187-193. PMID 26207261 DOI: 10.1016/j.dadm.2015.01.005  0.32
2015 Wang DB, Kinoshita Y, Kinoshita C, Uo T, Sopher BL, Cudaback E, Keene CD, Bilousova T, Gylys K, Case A, Jayadev S, Wang HG, Garden GA, Morrison RS. Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain : a Journal of Neurology. 138: 2005-19. PMID 25981964 DOI: 10.1093/brain/awv128  0.32
2015 Teng E, Chow N, Hwang KS, Thompson PM, Gylys KH, Cole GM, Jack CR, Shaw LM, Trojanowski JQ, Soares HD, Weiner MW, Apostolova LG. Low plasma ApoE levels are associated with smaller hippocampal size in the Alzheimer's disease neuroimaging initiative cohort. Dementia and Geriatric Cognitive Disorders. 39: 154-66. PMID 25547651 DOI: 10.1159/000368982  0.32
2015 Sokolow S, Henkins KM, Bilousova T, Gonzalez B, Vinters HV, Miller CA, Cornwell L, Poon WW, Gylys KH. Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease. Journal of Neurochemistry. 133: 368-79. PMID 25393609 DOI: 10.1111/jnc.12991  0.32
2014 Meyer DM, Eastwood JA, Compton MP, Gylys K, Zivin JA. rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. Biology of Sex Differences. 5: 9. PMID 25061508 DOI: 10.1186/2042-6410-5-9  0.32
2013 Meyer DM, Compton P, Eastwood JA, Gylys K, Zivin JA. Antiplatelet loading improves behavioral outcome in a rabbit model of stroke. Stroke; a Journal of Cerebral Circulation. 44: 3246-8. PMID 23982714 DOI: 10.1161/STROKEAHA.113.002565  0.32
2013 Tai LM, Bilousova T, Jungbauer L, Roeske SK, Youmans KL, Yu C, Poon WW, Cornwell LB, Miller CA, Vinters HV, Van Eldik LJ, Fardo DW, Estus S, Bu G, Gylys KH, et al. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. The Journal of Biological Chemistry. 288: 5914-26. PMID 23293020 DOI: 10.1074/jbc.M112.442103  0.32
2012 Ringman JM, Frautschy SA, Teng E, Begum AN, Bardens J, Beigi M, Gylys KH, Badmaev V, Heath DD, Apostolova LG, Porter V, Vanek Z, Marshall GA, Hellemann G, Sugar C, et al. Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study. Alzheimer's Research & Therapy. 4: 43. PMID 23107780 DOI: 10.1186/alzrt146  0.32
2012 Ringman JM, Elashoff D, Geschwind DH, Welsh BT, Gylys KH, Lee C, Cummings JL, Cole GM. Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype. Archives of Neurology. 69: 757-64. PMID 22689192 DOI: 10.1001/archneurol.2012.277  0.32
2012 Ringman JM, Fithian AT, Gylys K, Cummings JL, Coppola G, Elashoff D, Pratico D, Moskovitz J, Bitan G. Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations. Dementia and Geriatric Cognitive Disorders. 33: 219-25. PMID 22584618 DOI: 10.1159/000338546  0.32
2012 Henkins KM, Sokolow S, Miller CA, Vinters HV, Poon WW, Cornwell LB, Saing T, Gylys KH. Extensive p-tau pathology and SDS-stable p-tau oligomers in Alzheimer's cortical synapses. Brain Pathology (Zurich, Switzerland). 22: 826-33. PMID 22486774 DOI: 10.1111/j.1750-3639.2012.00598.x  0.32
2012 Ringman JM, Coppola G, Elashoff D, Rodriguez-Agudelo Y, Medina LD, Gylys K, Cummings JL, Cole GM. Cerebrospinal fluid biomarkers and proximity to diagnosis in preclinical familial Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 33: 1-5. PMID 22343824 DOI: 10.1159/000335729  0.32
2012 Ringman JM, Schulman H, Becker C, Jones T, Bai Y, Immermann F, Cole G, Sokolow S, Gylys K, Geschwind DH, Cummings JL, Wan HI. Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations. Archives of Neurology. 69: 96-104. PMID 22232349 DOI: 10.1001/archneurol.2011.642  0.32
2012 Sokolow S, Henkins KM, Williams IA, Vinters HV, Schmid I, Cole GM, Gylys KH. Isolation of synaptic terminals from Alzheimer's disease cortex. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 248-54. PMID 22213704 DOI: 10.1002/cyto.a.22009  0.32
2012 Arold S, Sullivan P, Bilousova T, Teng E, Miller CA, Poon WW, Vinters HV, Cornwell LB, Saing T, Cole GM, Gylys KH. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex. Acta Neuropathologica. 123: 39-52. PMID 22020632 DOI: 10.1007/s00401-011-0892-1  0.32
2012 Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, Gylys KH. Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex. Neurobiology of Disease. 45: 381-7. PMID 21914482 DOI: 10.1016/j.nbd.2011.08.027  0.32
2012 Sokolow S, Henkins KM, Bilousova T, Miller CA, Vinters HV, Poon W, Cole GM, Gylys KH. AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly. Neurobiology of Aging. 33: 1545-55. PMID 21741125 DOI: 10.1016/j.neurobiolaging.2011.05.011  0.32
2011 Meyer DM, Eastwood JA, Compton MP, Gylys K, Zivin JA, Ovbiagele B. Sex differences in antiplatelet response in ischemic stroke. Women's Health (London, England). 7: 465-74. PMID 21790339 DOI: 10.2217/whe.11.45  0.32
2011 Ringman JM, Taylor K, Teng E, Coppola G, Gylys K. Longitudinal change in CSF biomarkers in a presymptomatic carrier of an APP mutation. Neurology. 76: 2124-5. PMID 21562250 DOI: 10.1212/WNL.0b013e31821f4488  0.32
2011 Sokolow S, Luu SH, Headley AJ, Hanson AY, Kim T, Miller CA, Vinters HV, Gylys KH. High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease. Cell Calcium. 49: 208-16. PMID 21382638 DOI: 10.1016/j.ceca.2010.12.008  0.32
2011 Ringman JM, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, et al. Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation. Neuroscience Letters. 487: 287-92. PMID 21094210 DOI: 10.1016/j.neulet.2010.10.039  0.32
2011 Ringman JM, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, et al. Corrigendum to " Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation" [Neurosci. Lett. 487 (2011) 287-292] Neuroscience Letters. 491: 163. DOI: 10.1016/j.neulet.2011.01.021  0.32
2009 Wiley DJ, Elashoff D, Masongsong EV, Harper DM, Gylys KH, Silverberg MJ, Cook RL, Johnson-Hill LM. Smoking enhances risk for new external genital warts in men. International Journal of Environmental Research and Public Health. 6: 1215-34. PMID 19440442 DOI: 10.3390/ijerph6031215  0.32
2008 Ringman JM, Younkin SG, Pratico D, Seltzer W, Cole GM, Geschwind DH, Rodriguez-Agudelo Y, Schaffer B, Fein J, Sokolow S, Rosario ER, Gylys KH, Varpetian A, Medina LD, Cummings JL. Biochemical markers in persons with preclinical familial Alzheimer disease. Neurology. 71: 85-92. PMID 18509095 DOI: 10.1212/01.wnl.0000303973.71803.81  0.32
2008 Fein JA, Sokolow S, Miller CA, Vinters HV, Yang F, Cole GM, Gylys KH. Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes. The American Journal of Pathology. 172: 1683-92. PMID 18467692 DOI: 10.2353/ajpath.2008.070829  0.32
2007 Gylys KH, Fein JA, Yang F, Miller CA, Cole GM. Increased cholesterol in Abeta-positive nerve terminals from Alzheimer's disease cortex. Neurobiology of Aging. 28: 8-17. PMID 16332401 DOI: 10.1016/j.neurobiolaging.2005.10.018  0.32
2006 Wiley DJ, Wiesmeier E, Masongsong E, Gylys KH, Koutsky LA, Ferris DG, Barr E, Yu Rao J. Smokers at higher risk for undetected antibody for oncogenic human papillomavirus type 16 infection. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 915-20. PMID 16702370 DOI: 10.1158/1055-9965.EPI-05-0963  0.32
2004 Gylys KH, Fein JA, Yang F, Wiley DJ, Miller CA, Cole GM. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. The American Journal of Pathology. 165: 1809-17. PMID 15509549  0.32
2004 Gylys KH, Fein JA, Yang F, Cole GM. Enrichment of presynaptic and postsynaptic markers by size-based gating analysis of synaptosome preparations from rat and human cortex. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 60: 90-6. PMID 15229861 DOI: 10.1002/cyto.a.20031  0.32
2004 Gylys KH, Fein JA, Wiley DJ, Cole GM. Rapid annexin-V labeling in synaptosomes. Neurochemistry International. 44: 125-31. PMID 14568554 DOI: 10.1016/S0197-0186(03)00146-3  0.32
2003 Gylys KH, Fein JA, Tan AM, Cole GM. Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals. Journal of Neurochemistry. 84: 1442-51. PMID 12614344 DOI: 10.1046/j.1471-4159.2003.01643.x  0.32
2002 Gylys KH, Fein JA, Cole GM. Caspase inhibition protects nerve terminals from in vitro degradation. Neurochemical Research. 27: 465-72. PMID 12199150 DOI: 10.1023/A:1019840417796  0.32
2000 Gylys KH, Fein JA, Cole GM. Quantitative characterization of crude synaptosomal fraction (P-2) components by flow cytometry. Journal of Neuroscience Research. 61: 186-92. PMID 10878591 DOI: 10.1002/1097-4547(20000715)61:2<186::AID-JNR9>3.0.CO;2-X  0.32
1997 Gylys KH, Abdalah I, Jenden DJ. Selectivity of hemicholinium mustard, an affinity ligand, for the high-affinity choline transport system Neuropharmacology. 36: 1741-1746. PMID 9517446 DOI: 10.1016/S0028-3908(97)00175-5  0.32
1997 Gylys KH, Tran N, Magendzo K, Zaki P, Evans CJ. cAMP decreases steady-state levels of δ-opioid receptor mRNA in NG108- 15 cells Neuroreport. 8: 2369-2372. PMID 9243642  0.32
1996 Gylys KH, Jenden DJ. Regulation of acetylcholine synthesis in the presence of hemicholinium mustard Life Sciences. 58: 1937-1946. PMID 8637422 DOI: 10.1016/0024-3205(96)00183-X  0.32
1992 Gylys KH, Mellin C, Amstutz R, Jenden DJ. Characterization of the irreversible inhibition of high-affinity choline transport produced by hemicholinium mustard Journal of Neurochemistry. 59: 1302-1308. PMID 1402882  0.32
1988 Hersh LB, Takane K, Gylys K, Moomaw C, Slaughter C. Conservation of amino acid sequences between human and porcine choline acetyltransferase Journal of Neurochemistry. 51: 1843-1845. PMID 3183663  0.32
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