Gwenn A. Garden - Publications

Affiliations: 
Neurobiology and Behavior University of Washington, Seattle, Seattle, WA 
Area:
Neuroscience Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wang DB, Kinoshita C, Kinoshita Y, Sopher BL, Uo T, Lee RJ, Kim JK, Murphy SP, Keene CD, Garden GA, Morrison RS. Neuronal Susceptibility to Beta-Amyloid Toxicity and Ischemic Injury Involves Histone Deacetylase-2 Regulation of Endophilin-B1. Brain Pathology (Zurich, Switzerland). PMID 30028551 DOI: 10.1111/bpa.12647  0.56
2016 Möller T, Bard F, Bhattacharya A, Biber K, Campbell B, Dale E, Eder C, Gan L, Garden GA, Hughes ZA, Pearse DD, Staal RG, Sayed FA, Wes PD, Boddeke HW. Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor. Glia. PMID 27246804 DOI: 10.1002/glia.23007  0.64
2015 Aloi MS, Su W, Garden GA. The p53 Transcriptional Network Influences Microglia Behavior and Neuroinflammation. Critical Reviews in Immunology. 35: 401-15. PMID 26853851  0.64
2015 Su W, Aloi MS, Garden GA. MicroRNAs mediating CNS inflammation: Small regulators with powerful potential. Brain, Behavior, and Immunity. PMID 26148445 DOI: 10.1016/j.bbi.2015.07.003  0.64
2015 Wang DB, Kinoshita Y, Kinoshita C, Uo T, Sopher BL, Cudaback E, Keene CD, Bilousova T, Gylys K, Case A, Jayadev S, Wang HG, Garden GA, Morrison RS. Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain : a Journal of Neurology. 138: 2005-19. PMID 25981964 DOI: 10.1093/brain/awv128  0.64
2015 Jebelli J, Su W, Hopkins S, Pocock J, Garden GA. Glia: guardians, gluttons, or guides for the maintenance of neuronal connectivity? Annals of the New York Academy of Sciences. PMID 25752338 DOI: 10.1111/nyas.12711  0.64
2015 Su W, Kang J, Sopher B, Gillespie J, Aloi MS, Odom GL, Hopkins S, Case A, Wang DB, Chamberlain JS, Garden GA. Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia. Journal of Neurochemistry. PMID 25708596 DOI: 10.1111/jnc.13081  0.64
2015 Korvatska O, Leverenz JB, Jayadev S, McMillan P, Kurtz I, Guo X, Rumbaugh M, Matsushita M, Girirajan S, Dorschner MO, Kiianitsa K, Yu CE, Brkanac Z, Garden GA, Raskind WH, et al. R47H variant of TREM2 associated with Alzheimer disease in a large late-onset family clinical, genetic, and neuropathological study Jama Neurology. 72: 920-927.  0.64
2014 Hu R, Kagele DA, Huffaker TB, Runtsch MC, Alexander M, Liu J, Bake E, Su W, Williams MA, Rao DS, Möller T, Garden GA, Round JL, O'Connell RM. miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. Immunity. 41: 605-19. PMID 25367574 DOI: 10.1016/j.immuni.2014.09.015  0.64
2014 Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, Garden GA, La Spada AR. Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. Nature Neuroscience. 17: 1180-9. PMID 25108912 DOI: 10.1038/nn.3787  0.64
2014 Maung R, Hoefer MM, Sanchez AB, Sejbuk NE, Medders KE, Desai MK, Catalan IC, Dowling CC, de Rozieres CM, Garden GA, Russo R, Roberts AJ, Williams R, Kaul M. CCR5 knockout prevents neuronal injury and behavioral impairment induced in a transgenic mouse model by a CXCR4-using HIV-1 glycoprotein 120. Journal of Immunology (Baltimore, Md. : 1950). 193: 1895-910. PMID 25031461 DOI: 10.4049/jimmunol.1302915  0.64
2014 Wang DB, Uo T, Kinoshita C, Sopher BL, Lee RJ, Murphy SP, Kinoshita Y, Garden GA, Wang HG, Morrison RS. Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2674-83. PMID 24523556 DOI: 10.1523/JNEUROSCI.4074-13.2014  0.64
2014 Su W, Hopkins S, Nesser NK, Sopher B, Silvestroni A, Ammanuel S, Jayadev S, Möller T, Weinstein J, Garden GA. The p53 transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf. Journal of Immunology (Baltimore, Md. : 1950). 192: 358-66. PMID 24319262 DOI: 10.4049/jimmunol.1301397  0.64
2013 Garden GA. Epigenetics and the modulation of neuroinflammation. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 782-8. PMID 23963788 DOI: 10.1007/s13311-013-0207-4  0.64
2013 Jayadev S, Case A, Alajajian B, Eastman AJ, Möller T, Garden GA. Presenilin 2 influences miR146 level and activity in microglia. Journal of Neurochemistry. 127: 592-9. PMID 23952003 DOI: 10.1111/jnc.12400  0.64
2013 Wang DB, Garden GA, Kinoshita C, Wyles C, Babazadeh N, Sopher B, Kinoshita Y, Morrison RS. Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1357-65. PMID 23345212 DOI: 10.1523/JNEUROSCI.3365-12.2013  0.64
2013 Furrer SA, Waldherr SM, Mohanachandran MS, Baughn TD, Nguyen KT, Sopher BL, Damian VA, Garden GA, La Spada AR. Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7. Human Molecular Genetics. 22: 890-903. PMID 23197655 DOI: 10.1093/hmg/dds495  0.64
2012 Garden GA, La Spada AR. Intercellular (mis)communication in neurodegenerative disease. Neuron. 73: 886-901. PMID 22405200 DOI: 10.1016/j.neuron.2012.02.017  0.64
2012 Jebelli JD, Hooper C, Garden GA, Pocock JM. Emerging roles of p53 in glial cell function in health and disease. Glia. 60: 515-25. PMID 22105777 DOI: 10.1002/glia.22268  0.64
2011 Furrer SA, Mohanachandran MS, Waldherr SM, Chang C, Damian VA, Sopher BL, Garden GA, La Spada AR. Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16269-78. PMID 22072678 DOI: 10.1523/JNEUROSCI.4000-11.2011  0.64
2011 Jayadev S, Nesser NK, Hopkins S, Myers SJ, Case A, Lee RJ, Seaburg LA, Uo T, Murphy SP, Morrison RS, Garden GA. Transcription factor p53 influences microglial activation phenotype. Glia. 59: 1402-13. PMID 21598312 DOI: 10.1002/glia.21178  0.64
2010 Jayadev S, Case A, Eastman AJ, Nguyen H, Pollak J, Wiley JC, Möller T, Morrison RS, Garden GA. Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release. Plos One. 5: e15743. PMID 21206757 DOI: 10.1371/journal.pone.0015743  0.64
2010 Guyenet SJ, Furrer SA, Damian VM, Baughan TD, La Spada AR, Garden GA. A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia. Journal of Visualized Experiments : Jove. PMID 20495529 DOI: 10.3791/1787  0.64
2010 Underhill HR, Yuan C, Yarnykh VL, Chu B, Oikawa M, Dong L, Polissar NL, Garden GA, Cramer SC, Hatsukami TS. Predictors of surface disruption with MR imaging in asymptomatic carotid artery stenosis. Ajnr. American Journal of Neuroradiology. 31: 487-93. PMID 19833801 DOI: 10.3174/ajnr.A1842  0.64
2009 Chakrabarti L, Eng J, Ivanov N, Garden GA, La Spada AR. Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death. Molecular Brain. 2: 24. PMID 19640278 DOI: 10.1186/1756-6606-2-24  0.64
2009 Jayadev S, Garden GA. Host and viral factors influencing the pathogenesis of HIV-associated neurocognitive disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 175-89. PMID 19373562 DOI: 10.1007/s11481-009-9154-6  0.64
2009 Young JE, Garden GA, Martinez RA, Tanaka F, Sandoval CM, Smith AC, Sopher BL, Lin A, Fischbeck KH, Ellerby LM, Morrison RS, Taylor JP, La Spada AR. Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1987-97. PMID 19228953 DOI: 10.1523/JNEUROSCI.4072-08.2009  0.64
2008 Garden GA, La Spada AR. Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration. Cerebellum (London, England). 7: 138-49. PMID 18418675 DOI: 10.1007/s12311-008-0027-y  0.64
2007 Jayadev S, Yun B, Nguyen H, Yokoo H, Morrison RS, Garden GA. The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 359-70. PMID 18040854 DOI: 10.1007/s11481-007-9095-x  0.64
2007 Tun C, Guo W, Nguyen H, Yun B, Libby RT, Morrison RS, Garden GA. Activation of the extrinsic caspase pathway in cultured cortical neurons requires p53-mediated down-regulation of the X-linked inhibitor of apoptosis protein to induce apoptosis. Journal of Neurochemistry. 102: 1206-19. PMID 17488272 DOI: 10.1111/j.1471-4159.2007.04609.x  0.64
2007 Saam T, Yuan C, Chu B, Takaya N, Underhill H, Cai J, Tran N, Polissar NL, Neradilek B, Jarvik GP, Isaac C, Garden GA, Maravilla KR, Hashimoto B, Hatsukami TS. Predictors of carotid atherosclerotic plaque progression as measured by noninvasive magnetic resonance imaging. Atherosclerosis. 194: e34-42. PMID 16978632 DOI: 10.1016/j.atherosclerosis.2006.08.016  0.64
2006 Garden GA, Möller T. Microglia biology in health and disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 127-37. PMID 18040779 DOI: 10.1007/s11481-006-9015-5  0.64
2006 Kinoshita Y, Uo T, Jayadev S, Garden GA, Conrads TP, Veenstra TD, Morrison RS. Potential applications and limitations of proteomics in the study of neurological disease. Archives of Neurology. 63: 1692-6. PMID 17172608 DOI: 10.1001/archneur.63.12.1692  0.64
2006 Custer SK, Garden GA, Gill N, Rueb U, Libby RT, Schultz C, Guyenet SJ, Deller T, Westrum LE, Sopher BL, La Spada AR. Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nature Neuroscience. 9: 1302-11. PMID 16936724 DOI: 10.1038/nn1750  0.64
2006 Takaya N, Yuan C, Chu B, Saam T, Underhill H, Cai J, Tran N, Polissar NL, Isaac C, Ferguson MS, Garden GA, Cramer SC, Maravilla KR, Hashimoto B, Hatsukami TS. Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI--initial results. Stroke; a Journal of Cerebral Circulation. 37: 818-23. PMID 16469957 DOI: 10.1161/01.STR.0000204638.91099.91  0.64
2006 Garden GA, Truant R, Ellerby LM, La Spada AR. Spinocerebellar ataxia type 7: Clinical features to cellular pathogenesis Genetic Instabilities and Neurological Diseases, Second Edition. 399-416. DOI: 10.1016/B978-012369462-1/50028-4  0.64
2005 Garden GA, Morrison RS. The multiple roles of p53 in the pathogenesis of HIV associated dementia. Biochemical and Biophysical Research Communications. 331: 799-809. PMID 15865935 DOI: 10.1016/j.bbrc.2005.03.185  0.64
2004 Garden GA, Guo W, Jayadev S, Tun C, Balcaitis S, Choi J, Montine TJ, Möller T, Morrison RS. HIV associated neurodegeneration requires p53 in neurons and microglia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1141-3. PMID 15155568 DOI: 10.1096/fj.04-1676fje  0.64
2004 Hu S, Walker M, Czartoski T, Cheng A, Forghani B, Gilden DH, Garden GA. Acyclovir responsive brain stem disease after the Ramsay Hunt syndrome Journal of the Neurological Sciences. 217: 111-113. PMID 14675618 DOI: 10.1016/j.jns.2003.08.011  0.64
2003 Morrison RS, Kinoshita Y, Johnson MD, Guo W, Garden GA. p53-dependent cell death signaling in neurons. Neurochemical Research. 28: 15-27. PMID 12587660 DOI: 10.1023/A:1021687810103  0.64
2002 Garden GA. Microglia in human immunodeficiency virus-associated neurodegeneration. Glia. 40: 240-51. PMID 12379911 DOI: 10.1002/glia.10155  0.64
2002 Garden GA, Libby RT, Fu YH, Kinoshita Y, Huang J, Possin DE, Smith AC, Martinez RA, Fine GC, Grote SK, Ware CB, Einum DD, Morrison RS, Ptacek LJ, Sopher BL, et al. Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4897-905. PMID 12077187  0.64
2002 Garden GA, Budd SL, Tsai E, Hanson L, Kaul M, D'Emilia DM, Friedlander RM, Yuan J, Masliah E, Lipton SA. Caspase cascades in human immunodeficiency virus-associated neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4015-24. PMID 12019321  0.64
2001 Kaul M, Garden GA, Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature. 410: 988-94. PMID 11309629 DOI: 10.1038/35073667  0.64
1995 Garden GA, Redeker-DeWulf V, Rubel EW. Afferent influences on brainstem auditory nuclei of the chicken: regulation of transcriptional activity following cochlea removal. The Journal of Comparative Neurology. 359: 412-23. PMID 7499538 DOI: 10.1002/cne.903590305  0.64
1995 Garden GA, Hartlage-Rübsamen M, Rubel EW, Bothwell MA. Protein masking of a ribosomal RNA epitope is an early event in afferent deprivation-induced neuronal death. Molecular and Cellular Neurosciences. 6: 293-310. PMID 7496633 DOI: 10.1006/mcne.1995.1023  0.64
1994 Garden GA, Canady KS, Lurie DI, Bothwell M, Rubel EW. A biphasic change in ribosomal conformation during transneuronal degeneration is altered by inhibition of mitochondrial, but not cytoplasmic protein synthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1994-2008. PMID 8158254  0.64
1993 Garden GA, Moss GB, Emonyi W, Bwayo J, Velentgas P, Kreiss J. Beta-2 microglobulin as a marker of HIV disease status in Nairobi, Kenya International Journal of Std and Aids. 4: 49-51. PMID 8427903  0.64
1991 Garden GA, Bothwell M, Rubel EW. Lack of correspondence between mRNA expression for a putative cell death molecule (SGP-2) and neuronal cell death in the central nervous system. Journal of Neurobiology. 22: 590-604. PMID 1919566 DOI: 10.1002/neu.480220605  0.64
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