Paul S. Knoepfler - Publications

Neuroscience University of California, Davis, Davis, CA 
Neuroscience Biology, Cell Biology, Human Development

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Knoepfler PS. From bench to FDA to bedside: US regulatory trends for new stem cell therapies. Advanced Drug Delivery Reviews. 82: 192-6. PMID 25489841 DOI: 10.1016/j.addr.2014.12.001  1
2015 Tung PY, Knoepfler PS. Epigenetic mechanisms of tumorigenicity manifesting in stem cells Oncogene. 34: 2288-2296. PMID 24931168 DOI: 10.1038/onc.2014.172  1
2014 Yuen BT, Bush KM, Barrilleaux BL, Cotterman R, Knoepfler PS. Histone H3.3 regulates dynamic chromatin states during spermatogenesis. Development (Cambridge, England). 141: 3483-94. PMID 25142466 DOI: 10.1242/dev.106450  1
2014 Barrilleaux BL, Burow D, Lockwood SH, Yu A, Segal DJ, Knoepfler PS. Miz-1 activates gene expression via a novel consensus DNA binding motif. Plos One. 9: e101151. PMID 24983942 DOI: 10.1371/journal.pone.0101151  1
2013 Yuen BT, Knoepfler PS. Histone H3.3 mutations: a variant path to cancer. Cancer Cell. 24: 567-74. PMID 24229707 DOI: 10.1016/j.ccr.2013.09.015  1
2013 Knoepfler PS. Key action items for the stem cell field: looking ahead to 2014. Stem Cells and Development. 22: 10-2. PMID 24147571 DOI: 10.1089/scd.2013.0322  1
2013 Knoepfler PS. Scientists: you really need to get out of the lab more. Nature Medicine. 19: 1086. PMID 24013741 DOI: 10.1038/nm0913-1086  1
2013 Barrilleaux BL, Cotterman R, Knoepfler PS. Chromatin immunoprecipitation assays for Myc and N-Myc. Methods in Molecular Biology (Clifton, N.J.). 1012: 117-33. PMID 24006062 DOI: 10.1007/978-1-62703-429-6_9  1
2013 Tung PY, Varlakhanova NV, Knoepfler PS. Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes. Stem Cells (Dayton, Ohio). 31: 2330-42. PMID 23963736 DOI: 10.1002/stem.1526  1
2013 Laskowski AI, Knoepfler PS. Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain. Biochemical and Biophysical Research Communications. 435: 551-6. PMID 23665319 DOI: 10.1016/j.bbrc.2013.04.100  1
2013 Bush KM, Yuen BT, Barrilleaux BL, Riggs JW, O'Geen H, Cotterman RF, Knoepfler PS. Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development. Epigenetics & Chromatin. 6: 7. PMID 23570311 DOI: 10.1186/1756-8935-6-7  1
2013 Knoepfler PS. Call for fellowship programs in stem cell-based regenerative and cellular medicine: new stem cell training is essential for physicians. Regenerative Medicine. 8: 223-5. PMID 23477401 DOI: 10.2217/rme.13.1  1
2013 Riggs JW, Barrilleaux BL, Varlakhanova N, Bush KM, Chan V, Knoepfler PS. Induced pluripotency and oncogenic transformation are related processes. Stem Cells and Development. 22: 37-50. PMID 22998387 DOI: 10.1089/scd.2012.0375  1
2012 Laskowski AI, Knoepfler PS. Utf1: Goldilocks for ESC bivalency. Cell Stem Cell. 11: 732-4. PMID 23217417 DOI: 10.1016/j.stem.2012.11.012  1
2012 Meissen JK, Yuen BT, Kind T, Riggs JW, Barupal DK, Knoepfler PS, Fiehn O. Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism. Plos One. 7: e46770. PMID 23077522 DOI: 10.1371/journal.pone.0046770  1
2012 Knoepfler PS. Key anticipated regulatory issues for clinical use of human induced pluripotent stem cells. Regenerative Medicine. 7: 713-20. PMID 22830621 DOI: 10.2217/rme.12.51  1
2012 Martínez-Cerdeño V, Lemen JM, Chan V, Wey A, Lin W, Dent SR, Knoepfler PS. N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells. Plos One. 7: e39456. PMID 22745758 DOI: 10.1371/journal.pone.0039456  1
2012 Pshenichnaya I, Schouwey K, Armaro M, Larue L, Knoepfler PS, Eisenman RN, Trumpp A, Delmas V, Beermann F. Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc. Pigment Cell & Melanoma Research. 25: 312-25. PMID 22420299 DOI: 10.1111/j.1755-148X.2012.00998.x  1
2011 Varlakhanova N, Cotterman R, Bradnam K, Korf I, Knoepfler PS. Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells. Epigenetics & Chromatin. 4: 20. PMID 22053792 DOI: 10.1186/1756-8935-4-20  1
2011 Barrilleaux B, Knoepfler PS. Inducing iPSCs to escape the dish. Cell Stem Cell. 9: 103-11. PMID 21816362 DOI: 10.1016/j.stem.2011.07.006  1
2011 Domínguez-Frutos E, López-Hernández I, Vendrell V, Neves J, Gallozzi M, Gutsche K, Quintana L, Sharpe J, Knoepfler PS, Eisenman RN, Trumpp A, Giráldez F, Schimmang T. N-myc controls proliferation, morphogenesis, and patterning of the inner ear. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7178-89. PMID 21562282 DOI: 10.1523/JNEUROSCI.0785-11.2011  1
2010 Knoepfler PS. Arrestin' the hedgehog: Shh limits its own signaling via β-Arrestin1. Cell Cycle (Georgetown, Tex.). 9: 4260-1. PMID 21057198 DOI: 10.4161/cc.9.21.13530  1
2010 Wey A, Martinez Cerdeno V, Pleasure D, Knoepfler PS. c- and N-myc regulate neural precursor cell fate, cell cycle, and metabolism to direct cerebellar development. Cerebellum (London, England). 9: 537-47. PMID 20658325 DOI: 10.1007/s12311-010-0190-9  1
2010 Wey A, Knoepfler PS. c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain. Oncotarget. 1: 120-30. PMID 20651942 DOI: 10.18632/oncotarget.116  1
2010 Varlakhanova NV, Cotterman RF, deVries WN, Morgan J, Donahue LR, Murray S, Knowles BB, Knoepfler PS. myc maintains embryonic stem cell pluripotency and self-renewal. Differentiation; Research in Biological Diversity. 80: 9-19. PMID 20537458 DOI: 10.1016/j.diff.2010.05.001  1
2010 Kuwahara A, Hirabayashi Y, Knoepfler PS, Taketo MM, Sakai J, Kodama T, Gotoh Y. Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development (Cambridge, England). 137: 1035-44. PMID 20215343 DOI: 10.1242/dev.046417  1
2010 Knoepfler PS, Bush KM. The death of MyMouseHouse: lessons for systems for the efficient management of mouse colonies. Disease Models & Mechanisms. 3: 9-10. PMID 20075375 DOI: 10.1242/dmm.004770  1
2010 Wey A, Knoepfler PS. C-myc and N-myc in the developing brain Aging. 2: 261-262.  1
2009 Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R. Division and apoptosis of E2f-deficient retinal progenitors. Nature. 462: 925-9. PMID 20016601 DOI: 10.1038/nature08544  1
2009 Varlakhanova NV, Knoepfler PS. Acting locally and globally: Myc's ever-expanding roles on chromatin. Cancer Research. 69: 7487-90. PMID 19773445 DOI: 10.1158/0008-5472.CAN-08-4832  1
2009 Cotterman R, Knoepfler PS. N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b. Plos One. 4: e5799. PMID 19495417 DOI: 10.1371/journal.pone.0005799  1
2009 Knoepfler PS. Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells (Dayton, Ohio). 27: 1050-6. PMID 19415771 DOI: 10.1002/stem.37  1
2008 Cotterman R, Jin VX, Krig SR, Lemen JM, Wey A, Farnham PJ, Knoepfler PS. N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. Cancer Research. 68: 9654-62. PMID 19047142 DOI: 10.1158/0008-5472.CAN-08-1961  1
2008 Laurenti E, Varnum-Finney B, Wilson A, Ferrero I, Blanco-Bose WE, Ehninger A, Knoepfler PS, Cheng PF, MacDonald HR, Eisenman RN, Bernstein ID, Trumpp A. Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. Cell Stem Cell. 3: 611-24. PMID 19041778 DOI: 10.1016/j.stem.2008.09.005  1
2008 Knoepfler PS. Why myc? An unexpected ingredient in the stem cell cocktail. Cell Stem Cell. 2: 18-21. PMID 18371417 DOI: 10.1016/j.stem.2007.12.004  1
2008 Knoepfler PS. Stem cells on the brain. Archives of Neurology. 65: 311-5. PMID 18332242 DOI: 10.1001/archneur.65.3.311  1
2008 Martins RA, Zindy F, Donovan S, Zhang J, Pounds S, Wey A, Knoepfler PS, Eisenman RN, Roussel MF, Dyer MA. N-myc coordinates retinal growth with eye size during mouse development. Genes & Development. 22: 179-93. PMID 18198336 DOI: 10.1101/gad.1608008  1
2007 Habib T, Park H, Tsang M, de Alborán IM, Nicks A, Wilson L, Knoepfler PS, Andrews S, Rawlings DJ, Eisenman RN, Iritani BM. Myc stimulates B lymphocyte differentiation and amplifies calcium signaling. The Journal of Cell Biology. 179: 717-31. PMID 17998397 DOI: 10.1083/jcb.200704173  1
2007 Knoepfler PS. Myc goes global: new tricks for an old oncogene. Cancer Research. 67: 5061-3. PMID 17545579 DOI: 10.1158/0008-5472.CAN-07-0426  1
2006 Hatton BA, Knoepfler PS, Kenney AM, Rowitch DH, de Alborán IM, Olson JM, Eisenman RN. N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth. Cancer Research. 66: 8655-61. PMID 16951180 DOI: 10.1158/0008-5472.CAN-06-1621  1
2006 Zindy F, Knoepfler PS, Xie S, Sherr CJ, Eisenman RN, Roussel MF. N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development. Proceedings of the National Academy of Sciences of the United States of America. 103: 11579-83. PMID 16864777 DOI: 10.1073/pnas.0604727103  1
2006 Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN. Myc influences global chromatin structure. The Embo Journal. 25: 2723-34. PMID 16724113 DOI: 10.1038/sj.emboj.7601152  1
2006 Knoepfler PS, Kenney AM. Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes. Cell Cycle (Georgetown, Tex.). 5: 47-52. PMID 16322694  1
2005 Orian A, Grewal SS, Knoepfler PS, Edgar BA, Parkhurst SM, Eisenman RN. Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors. Cold Spring Harbor Symposia On Quantitative Biology. 70: 299-307. PMID 16869766 DOI: 10.1101/sqb.2005.70.019  1
2005 Okubo T, Knoepfler PS, Eisenman RN, Hogan BL. Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development (Cambridge, England). 132: 1363-74. PMID 15716345 DOI: 10.1242/dev.01678  1
2004 Swanson KA, Knoepfler PS, Huang K, Kang RS, Cowley SM, Laherty CD, Eisenman RN, Radhakrishnan I. HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. Nature Structural & Molecular Biology. 11: 738-46. PMID 15235594 DOI: 10.1038/nsmb798  1
2004 Berkes CA, Bergstrom DA, Penn BH, Seaver KJ, Knoepfler PS, Tapscott SJ. Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential. Molecular Cell. 14: 465-77. PMID 15149596 DOI: 10.1016/S1097-2765(04)00260-6  1
2002 Knoepfler PS, Cheng PF, Eisenman RN. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes & Development. 16: 2699-712. PMID 12381668 DOI: 10.1101/gad.1021202  1
2001 Calvo KR, Knoepfler PS, Sykes DB, Pasillas MP, Kamps MP. Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 98: 13120-5. PMID 11687616 DOI: 10.1073/pnas.231115398  1
2001 Knoepfler PS, Sykes DB, Pasillas M, Kamps MP. HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation. Oncogene. 20: 5440-8. PMID 11571641 DOI: 10.1038/sj.onc.1204710  1
2001 Wotton D, Knoepfler PS, Laherty CD, Eisenman RN, Massagué J. The Smad transcriptional corepressor TGIF recruits mSin3. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 12: 457-63. PMID 11571228  1
2000 Jaw TJ, You LR, Knoepfler PS, Yao LC, Pai CY, Tang CY, Chang LP, Berthelsen J, Blasi F, Kamps MP, Sun YH. Direct interaction of two homeoproteins, homothorax and extradenticle, is essential for EXD nuclear localization and function. Mechanisms of Development. 91: 279-91. PMID 10704852 DOI: 10.1016/S0925-4773(99)00316-0  1
1999 Calvo KR, Knoepfler P, McGrath S, Kamps MP. An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1. Oncogene. 18: 8033-43. PMID 10637514 DOI: 10.1038/sj.onc.1203377  1
1999 Knoepfler PS, Eisenman RN. Sin meets NuRD and other tails of repression. Cell. 99: 447-50. PMID 10589671  1
1999 Knoepfler PS, Bergstrom DA, Uetsuki T, Dac-Korytko I, Sun YH, Wright WE, Tapscott SJ, Kamps MP. A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1. Nucleic Acids Research. 27: 3752-61. PMID 10471746 DOI: 10.1093/nar/27.18.3752  1
1997 Knoepfler PS, Calvo KR, Chen H, Antonarakis SE, Kamps MP. Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. Proceedings of the National Academy of Sciences of the United States of America. 94: 14553-8. PMID 9405651 DOI: 10.1073/pnas.94.26.14553  1
1997 Knoepfler PS, Kamps MP. The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I Hox proteins - evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements. Oncogene. 14: 2521-31. PMID 9191052 DOI: 10.1038/sj.onc.1201097  1
1997 Knoepfler PS, Kamps MP. The Pbx family of proteins is strongly upregulated by a post-transcriptional mechanism during retinoic acid-induced differentiation of P19 embryonal carcinoma cells. Mechanisms of Development. 63: 5-14. PMID 9178252 DOI: 10.1016/S0925-4773(97)00669-2  1
1996 Knoepfler PS, Lu Q, Kamps MP. Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif. Nucleic Acids Research. 24: 2288-94. PMID 8710498  1
1995 Knoepfler PS, Bloor CM, Carroll SM. Urokinase plasminogen activator activity is increased in the myocardium during coronary artery occlusion. Journal of Molecular and Cellular Cardiology. 27: 1317-24. PMID 8531214  1
1995 Lu Q, Knoepfler PS, Scheele J, Wright DD, Kamps MP. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes. Molecular and Cellular Biology. 15: 3786-95. PMID 7791786  1
1995 Knoepfler PS, Kamps MP. The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1. Molecular and Cellular Biology. 15: 5811-9. PMID 7565734  1
1995 Carroll SM, Nimmo LE, Knoepfler PS, White FC, Bloor CM. Gene expression in a swine model of right ventricular hypertrophy: intercellular adhesion molecule, vascular endothelial growth factor and plasminogen activators are upregulated during pressure overload. Journal of Molecular and Cellular Cardiology. 27: 1427-41. PMID 7473788 DOI: 10.1006/jmcc.1995.0135  1
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