David R. Lynch - Publications

Affiliations: 
Neuroscience University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neuroscience Biology

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Year Citation  Score
2018 Dong YN, McMillian E, Clark EM, Lin H, Lynch DR. GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich Ataxia cellular models. Human Molecular Genetics. PMID 30590615 DOI: 10.1093/Hmg/Ddy448  0.306
2018 Sharma R, Al-Saleem FH, Panzer J, Lee J, Puligedda RD, Felicori LF, Kattala CD, Rattelle AJ, Ippolito G, Cox RH, Lynch DR, Dessain SK. Monoclonal antibodies from a patient with anti-NMDA receptor encephalitis. Annals of Clinical and Translational Neurology. 5: 935-951. PMID 30128318 DOI: 10.1002/Acn3.592  0.389
2018 Sharma R, Al-Saleem FH, Puligedda RD, Rattelle A, Lynch DR, Dessain SK. Membrane-bound and soluble forms of an NMDA receptor extracellular domain retain epitopes targeted in auto-immune encephalitis. Bmc Biotechnology. 18: 41. PMID 29945600 DOI: 10.1186/S12896-018-0450-1  0.386
2018 Salovin A, Glanzman J, Roslin K, Armangue T, Lynch DR, Panzer JA. Anti-NMDA receptor encephalitis and nonencephalitic HSV-1 infection. Neurology(R) Neuroimmunology & Neuroinflammation. 5: e458. PMID 29629396 DOI: 10.1212/Nxi.0000000000000458  0.326
2018 Lynch DR, Rattelle A, Dong YN, Roslin K, Gleichman AJ, Panzer JA. Anti-NMDA Receptor Encephalitis: Clinical Features and Basic Mechanisms. Advances in Pharmacology (San Diego, Calif.). 82: 235-260. PMID 29413523 DOI: 10.1016/Bs.Apha.2017.08.005  0.772
2015 Lazaropoulos M, Dong Y, Clark E, Greeley NR, Seyer LA, Brigatti KW, Christie C, Perlman SL, Wilmot GR, Gomez CM, Mathews KD, Yoon G, Zesiewicz T, Hoyle C, Subramony SH, ... ... Lynch DR, et al. Frataxin levels in peripheral tissue in Friedreich ataxia. Annals of Clinical and Translational Neurology. 2: 831-42. PMID 26339677 DOI: 10.1002/Acn3.225  0.455
2015 Panzer JA, Anand R, Dalmau J, Lynch DR. Antibodies to dendritic neuronal surface antigens in opsoclonus myoclonus ataxia syndrome. Journal of Neuroimmunology. 286: 86-92. PMID 26298330 DOI: 10.1016/J.Jneuroim.2015.07.007  0.316
2015 Worth AJ, Basu SS, Deutsch EC, Hwang WT, Snyder NW, Lynch DR, Blair IA. Stable isotopes and LC-MS for monitoring metabolic disturbances in Friedreich's ataxia platelets. Bioanalysis. 7: 1843-55. PMID 26295986 DOI: 10.4155/Bio.15.118  0.439
2015 Zyskind JW, Wang Y, Cho G, Ting JH, Kolson DL, Lynch DR, Jordan-Sciutto KL. E2F1 in neurons is cleaved by calpain in an NMDA receptor-dependent manner in a model of HIV-induced neurotoxicity. Journal of Neurochemistry. 132: 742-55. PMID 25279448 DOI: 10.1111/Jnc.12956  0.357
2014 Adang LA, Lynch DR, Panzer JA. Pediatric anti-NMDA receptor encephalitis is seasonal. Annals of Clinical and Translational Neurology. 1: 921-5. PMID 25540806 DOI: 10.1002/Acn3.100  0.361
2014 Doss S, Wandinger KP, Hyman BT, Panzer JA, Synofzik M, Dickerson B, Mollenhauer B, Scherzer CR, Ivinson AJ, Finke C, Schöls L, Müller Vom Hagen J, Trenkwalder C, Jahn H, Höltje M, ... ... Lynch DR, et al. High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types. Annals of Clinical and Translational Neurology. 1: 822-32. PMID 25493273 DOI: 10.1002/Acn3.120  0.367
2014 Lynch DR, Fischbeck KH. Nicotinamide in Friedreich's ataxia: useful or not? Lancet. 384: 474-5. PMID 24794818 DOI: 10.1016/S0140-6736(14)60573-0  0.309
2014 Gleichman AJ, Panzer JA, Baumann BH, Dalmau J, Lynch DR. Antigenic and mechanistic characterization of anti-AMPA receptor encephalitis. Annals of Clinical and Translational Neurology. 1: 180-189. PMID 24707504 DOI: 10.1002/Acn3.43  0.757
2014 Deutsch EC, Oglesbee D, Greeley NR, Lynch DR. Usefulness of frataxin immunoassays for the diagnosis of Friedreich ataxia. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 994-1002. PMID 24463479 DOI: 10.1136/Jnnp-2013-306788  0.48
2014 Panzer JA, Gleichman AJ, Lynch DR. Glutamatergic autoencephalitides: an emerging field. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 957-68. PMID 24402576 DOI: 10.1007/S00702-013-1152-4  0.775
2014 Gresa-Arribas N, Titulaer MJ, Torrents A, Aguilar E, McCracken L, Leypoldt F, Gleichman AJ, Balice-Gordon R, Rosenfeld MR, Lynch D, Graus F, Dalmau J. Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study. The Lancet. Neurology. 13: 167-77. PMID 24360484 DOI: 10.1016/S1474-4422(13)70282-5  0.761
2014 Lin H, Hsu FC, Baumann BH, Coulter DA, Lynch DR. Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases. Neurobiology of Disease. 63: 129-40. PMID 24326163 DOI: 10.1016/J.Nbd.2013.11.021  0.32
2013 Basu SS, Deutsch EC, Schmaier AA, Lynch DR, Blair IA. Human platelets as a platform to monitor metabolic biomarkers using stable isotopes and LC-MS. Bioanalysis. 5: 3009-21. PMID 24320127 DOI: 10.4155/Bio.13.269  0.435
2013 Oglesbee D, Kroll C, Gakh O, Deutsch EC, Lynch DR, Gavrilova R, Tortorelli S, Raymond K, Gavrilov D, Rinaldo P, Matern D, Isaya G. High-throughput immunoassay for the biochemical diagnosis of Friedreich ataxia in dried blood spots and whole blood. Clinical Chemistry. 59: 1461-9. PMID 23838345 DOI: 10.1373/Clinchem.2013.207472  0.446
2013 Plasterer HL, Deutsch EC, Belmonte M, Egan E, Lynch DR, Rusche JR. Development of frataxin gene expression measures for the evaluation of experimental treatments in Friedreich's ataxia. Plos One. 8: e63958. PMID 23691127 DOI: 10.1371/Journal.Pone.0063958  0.473
2013 Panzer JA, Lynch DR. Neuroimmunology: Treatment of anti-NMDA receptor encephalitis--time to be bold? Nature Reviews. Neurology. 9: 187-9. PMID 23458972 DOI: 10.1038/Nrneurol.2013.31  0.359
2012 Gleichman AJ, Spruce LA, Dalmau J, Seeholzer SH, Lynch DR. Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11082-94. PMID 22875940 DOI: 10.1523/Jneurosci.0064-12.2012  0.765
2012 Lynch DR, Deutsch EC, Wilson RB, Tennekoon G. Unanswered questions in Friedreich ataxia. Journal of Child Neurology. 27: 1223-9. PMID 22832776 DOI: 10.1177/0883073812453498  0.465
2012 Brigatti KW, Deutsch EC, Lynch DR, Farmer JM. Novel diagnostic paradigms for Friedreich ataxia. Journal of Child Neurology. 27: 1146-51. PMID 22752491 DOI: 10.1177/0883073812448440  0.47
2012 Deutsch EC, Seyer LA, Perlman SL, Yu J, Lynch DR. Clinical monitoring in a patient with Friedreich ataxia and osteogenic sarcoma. Journal of Child Neurology. 27: 1159-63. PMID 22752483 DOI: 10.1177/0883073812448460  0.484
2012 Lynch DR, Willi SM, Wilson RB, Cotticelli MG, Brigatti KW, Deutsch EC, Kucheruk O, Shrader W, Rioux P, Miller G, Hawi A, Sciascia T. A0001 in Friedreich ataxia: biochemical characterization and effects in a clinical trial. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1026-33. PMID 22744651 DOI: 10.1002/Mds.25058  0.446
2012 Snyder M, Seyer L, Lynch DR, Resnick A, Zesiewicz TA. Cardiac dysfunction exacerbated by endocrinopathies in Friedreich ataxia: a case series. Journal of Child Neurology. 27: 1316-9. PMID 22408141 DOI: 10.1177/0883073811435242  0.49
2012 Singh P, Doshi S, Spaethling JM, Hockenberry AJ, Patel TP, Geddes-Klein DM, Lynch DR, Meaney DF. N-methyl-D-aspartate receptor mechanosensitivity is governed by C terminus of NR2B subunit. The Journal of Biological Chemistry. 287: 4348-59. PMID 22179603 DOI: 10.1074/Jbc.M111.253740  0.359
2011 Cook DR, Gleichman AJ, Cross SA, Doshi S, Ho W, Jordan-Sciutto KL, Lynch DR, Kolson DL. NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury. Journal of Neurochemistry. 118: 1113-23. PMID 21749375 DOI: 10.1111/J.1471-4159.2011.07383.X  0.753
2011 Selak MA, Lyver E, Micklow E, Deutsch EC, Onder O, Selamoglu N, Yager C, Knight S, Carroll M, Daldal F, Dancis A, Lynch DR, Sarry JE. Blood cells from Friedreich ataxia patients harbor frataxin deficiency without a loss of mitochondrial function. Mitochondrion. 11: 342-50. PMID 21147271 DOI: 10.1016/J.Mito.2010.12.003  0.466
2010 Lin H, Vicini S, Hsu FC, Doshi S, Takano H, Coulter DA, Lynch DR. Axonal α7 nicotinic ACh receptors modulate presynaptic NMDA receptor expression and structural plasticity of glutamatergic presynaptic boutons. Proceedings of the National Academy of Sciences of the United States of America. 107: 16661-6. PMID 20817852 DOI: 10.1073/Pnas.1007397107  0.301
2010 Deutsch EC, Santani AB, Perlman SL, Farmer JM, Stolle CA, Marusich MF, Lynch DR. A rapid, noninvasive immunoassay for frataxin: utility in assessment of Friedreich ataxia. Molecular Genetics and Metabolism. 101: 238-45. PMID 20675166 DOI: 10.1016/J.Ymgme.2010.07.001  0.496
2010 Hughes EG, Peng X, Gleichman AJ, Lai M, Zhou L, Tsou R, Parsons TD, Lynch DR, Dalmau J, Balice-Gordon RJ. Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5866-75. PMID 20427647 DOI: 10.1523/Jneurosci.0167-10.2010  0.77
2009 Florance NR, Davis RL, Lam C, Szperka C, Zhou L, Ahmad S, Campen CJ, Moss H, Peter N, Gleichman AJ, Glaser CA, Lynch DR, Rosenfeld MR, Dalmau J. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Annals of Neurology. 66: 11-8. PMID 19670433 DOI: 10.1002/Ana.21756  0.74
2009 Doshi S, Lynch DR. Calpain and the glutamatergic synapse. Frontiers in Bioscience (Scholar Edition). 1: 466-76. PMID 19482714 DOI: 10.2741/S38  0.362
2009 Lai M, Hughes EG, Peng X, Zhou L, Gleichman AJ, Shu H, Matà S, Kremens D, Vitaliani R, Geschwind MD, Bataller L, Kalb RG, Davis R, Graus F, Lynch DR, et al. AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Annals of Neurology. 65: 424-34. PMID 19338055 DOI: 10.1002/Ana.21589  0.77
2008 Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M, Dessain SK, Rosenfeld MR, Balice-Gordon R, Lynch DR. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. The Lancet. Neurology. 7: 1091-8. PMID 18851928 DOI: 10.1016/S1474-4422(08)70224-2  0.777
2008 Iizuka T, Sakai F, Ide T, Monzen T, Yoshii S, Iigaya M, Suzuki K, Lynch DR, Suzuki N, Hata T, Dalmau J. Anti-NMDA receptor encephalitis in Japan: long-term outcome without tumor removal. Neurology. 70: 504-11. PMID 17898324 DOI: 10.1212/01.Wnl.0000278388.90370.C3  0.326
2007 Wu HY, Hsu FC, Gleichman AJ, Baconguis I, Coulter DA, Lynch DR. Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems. The Journal of Biological Chemistry. 282: 20075-87. PMID 17526495 DOI: 10.1074/Jbc.M700624200  0.764
2007 Sansing LH, Tüzün E, Ko MW, Baccon J, Lynch DR, Dalmau J. A patient with encephalitis associated with NMDA receptor antibodies. Nature Clinical Practice. Neurology. 3: 291-6. PMID 17479076 DOI: 10.1038/Ncpneuro0493  0.361
2007 Waxman EA, Baconguis I, Lynch DR, Robinson MB. N-methyl-D-aspartate receptor-dependent regulation of the glutamate transporter excitatory amino acid carrier 1. The Journal of Biological Chemistry. 282: 17594-607. PMID 17459877 DOI: 10.1074/Jbc.M702278200  0.737
2007 Lynch DR, Gleichman AJ. Picking up the pieces: the roles of functional remnants of calpain-mediated proteolysis. Neuron. 53: 317-9. PMID 17270728 DOI: 10.1016/J.Neuron.2007.01.014  0.728
2007 Dalmau J, Tüzün E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, Mason W, Sansing LH, Dichter MA, Rosenfeld MR, Lynch DR. Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Annals of Neurology. 61: 25-36. PMID 17262855 DOI: 10.1002/Ana.21050  0.401
2006 Wu HY, Lynch DR. Calpain and synaptic function. Molecular Neurobiology. 33: 215-36. PMID 16954597 DOI: 10.1385/Mn:33:3:215  0.305
2006 Dong YN, Wu HY, Hsu FC, Coulter DA, Lynch DR. Developmental and cell-selective variations in N-methyl-D-aspartate receptor degradation by calpain. Journal of Neurochemistry. 99: 206-17. PMID 16899064 DOI: 10.1111/J.1471-4159.2006.04096.X  0.366
2006 Chen YZ, Hashemi SH, Anderson SK, Huang Y, Moreira MC, Lynch DR, Glass IA, Chance PF, Bennett CL. Senataxin, the yeast Sen1p orthologue: characterization of a unique protein in which recessive mutations cause ataxia and dominant mutations cause motor neuron disease. Neurobiology of Disease. 23: 97-108. PMID 16644229 DOI: 10.1016/J.Nbd.2006.02.007  0.301
2005 Waxman EA, Lynch DR. N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase. The Journal of Biological Chemistry. 280: 29322-33. PMID 15967799 DOI: 10.1074/Jbc.M502080200  0.716
2005 Waxman EA, Lynch DR. N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 37-49. PMID 15632277 DOI: 10.1177/1073858404269012  0.74
2004 Dong YN, Waxman EA, Lynch DR. Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11035-45. PMID 15590920 DOI: 10.1523/Jneurosci.3722-04.2004  0.737
2004 Baybis M, Lynch D, Lee A, Patel A, McKhann G, Chugani D, J Kupsky W, Aronica E, Crino PB. Altered expression of neurotransmitter-receptor subunit and uptake site mRNAs in hemimegalencephaly. Epilepsia. 45: 1517-24. PMID 15571509 DOI: 10.1111/J.0013-9580.2004.16204.X  0.332
2003 Simpkins KL, Guttmann RP, Dong Y, Chen Z, Sokol S, Neumar RW, Lynch DR. Selective activation induced cleavage of the NR2B subunit by calpain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11322-31. PMID 14672996 DOI: 10.1523/Jneurosci.23-36-11322.2003  0.392
2002 Guttmann RP, Sokol S, Baker DL, Simpkins KL, Dong Y, Lynch DR. Proteolysis of the N-methyl-d-aspartate receptor by calpain in situ. The Journal of Pharmacology and Experimental Therapeutics. 302: 1023-30. PMID 12183659 DOI: 10.1124/Jpet.102.036962  0.36
2002 Lynch DR, Guttmann RP. Excitotoxicity: perspectives based on N-methyl-D-aspartate receptor subtypes. The Journal of Pharmacology and Experimental Therapeutics. 300: 717-23. PMID 11861773 DOI: 10.1124/Jpet.300.3.717  0.377
2001 Raol YH, Lynch DR, Brooks-Kayal AR. Role of excitatory amino acids in developmental epilepsies Mental Retardation and Developmental Disabilities Research Reviews. 7: 254-260. PMID 11754519 DOI: 10.1002/Mrdd.1035  0.359
2001 Lynch DR, Guttmann RP. NMDA receptor pharmacology: Perspectives from molecular biology Current Drug Targets. 2: 215-231. PMID 11554549 DOI: 10.2174/1389450013348434  0.366
2001 Guttmann RP, Baker DL, Seifert KM, Cohen AS, Coulter DA, Lynch DR. Specific proteolysis of the NR2 subunit at multiple sites by calpain. Journal of Neurochemistry. 78: 1083-93. PMID 11553682 DOI: 10.1046/J.1471-4159.2001.00493.X  0.37
2001 Grant ER, Guttmann RP, Seifert KM, Lynch DR. A region of the rat N-methyl-D-aspartate receptor 2A subunit that is sufficient for potentiation by phorbol esters. Neuroscience Letters. 310: 9-12. PMID 11524145 DOI: 10.1016/S0304-3940(01)02085-7  0.352
2001 Lynch DR, Shim SS, Seifert KM, Kurapathi S, Mutel V, Gallagher MJ, Guttmann RP. Pharmacological characterization of interactions of RO 25-6981 with the NR2B (ε2) subunit European Journal of Pharmacology. 416: 185-195. PMID 11290368 DOI: 10.1016/S0014-2999(01)00868-8  0.336
2001 White R, Hua Y, Scheithauer B, Lynch DR, Henske EP, Crino PB. Selective alterations in glutamate and GABA receptor subunit mRNA expression in dysplastic neurons and giant cells of cortical tubers. Annals of Neurology. 49: 67-78. PMID 11198298 DOI: 10.1002/1531-8249(200101)49:1<67::Aid-Ana10>3.0.Co;2-L  0.313
2000 Siegel RM, Frederiksen JK, Zacharias DA, Chan FK, Johnson M, Lynch D, Tsien RY, Lenardo MJ. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations. Science (New York, N.Y.). 288: 2354-7. PMID 10875918 DOI: 10.1126/Science.288.5475.2354  0.304
2000 Anegawa NJ, Guttmann RP, Grant ER, Anand R, Lindstrom J, Lynch DR. N-Methyl-D-aspartate receptor mediated toxicity in nonneuronal cell lines: characterization using fluorescent measures of cell viability and reactive oxygen species production. Brain Research. Molecular Brain Research. 77: 163-75. PMID 10837912 DOI: 10.1016/S0169-328X(00)00050-4  0.325
1999 Shim SS, Grant ER, Singh S, Gallagher MJ, Lynch DR. Actions of butyrophenones and other antipsychotic agents at NMDA receptors: relationship with clinical effects and structural considerations. Neurochemistry International. 34: 167-75. PMID 10213076 DOI: 10.1016/S0197-0186(98)00085-0  0.368
1998 Grant ER, Bacskai BJ, Anegawa NJ, Pleasure DE, Lynch DR. Opposing contributions of NR1 and NR2 to protein kinase C modulation of NMDA receptors. Journal of Neurochemistry. 71: 1471-81. PMID 9751180 DOI: 10.1046/J.1471-4159.1998.71041471.X  0.342
1998 Gallagher MJ, Huang H, Lynch DR. Modulation of the N-methyl-D-aspartate receptor by haloperidol: NR2B- specific interactions Journal of Neurochemistry. 70: 2120-2128. PMID 9572299 DOI: 10.1046/J.1471-4159.1998.70052120.X  0.351
1997 Gallagher MJ, Huang H, Grant ER, Lynch DR. The NR2B-specific interactions of polyamines and protons with the N-methyl-D-aspartate receptor. The Journal of Biological Chemistry. 272: 24971-9. PMID 9312102 DOI: 10.1074/Jbc.272.40.24971  0.327
1997 Grant ER, Bacskai BJ, Pleasure DE, Pritchett DB, Gallagher MJ, Kendrick SJ, Kricka LJ, Lynch DR. N-methyl-D-aspartate receptors expressed in a nonneuronal cell line mediate subunit-specific increases in free intracellular calcium. The Journal of Biological Chemistry. 272: 647-56. PMID 8995308 DOI: 10.1074/Jbc.272.1.647  0.32
1996 Kendrick SJ, Lynch DR, Pritchett DB. Characterization of glutamate binding sites in receptors assembled from transfected NMDA receptor subunits. Journal of Neurochemistry. 67: 608-16. PMID 8764586 DOI: 10.1046/J.1471-4159.1996.67020608.X  0.342
1996 Gallagher MJ, Huang H, Pritchett DB, Lynch DR. Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor. The Journal of Biological Chemistry. 271: 9603-11. PMID 8621635 DOI: 10.1074/Jbc.271.16.9603  0.36
1995 Anegawa NJ, Lynch DR, Verdoorn TA, Pritchett DB. Transfection of N-methyl-D-aspartate receptors in a nonneuronal cell line leads to cell death. Journal of Neurochemistry. 64: 2004-12. PMID 7722486 DOI: 10.1046/J.1471-4159.1995.64052004.X  0.362
1994 Broussard DL, Li X, Pritchett DB, Lynch D, Bannermann PG, Pleasure D. The expression of a NMDA receptor gene in guinea-pig myenteric plexus. Neuroreport. 5: 973-6. PMID 8061307 DOI: 10.1097/00001756-199404000-00030  0.357
1994 Lynch DR, Dawson TM. Secondary mechanisms in neuronal trauma Current Opinion in Neurology. 7: 510-516. PMID 7866582 DOI: 10.1097/00019052-199412000-00007  0.509
1992 Lynch DR, Dawson TM, Raps EC, Galetta SL. Risk Factors for the Neurologic Complications Associated with Aortic Aneurysms Archives of Neurology. 49: 284-288. PMID 1311168 DOI: 10.1001/Archneur.1992.00530270098025  0.423
1989 Lynch D, Walker M, Miller R, Snyder S. Neuropeptide Y receptor binding sites in rat brain: differential autoradiographic localizations with 125I-peptide YY and 125I- neuropeptide Y imply receptor heterogeneity The Journal of Neuroscience. 9: 2607-2619. DOI: 10.1523/Jneurosci.09-08-02607.1989  0.393
1988 Lynch DR, Venable JC, Strittmatter SM, Snyder SH. Enkephalin convertase: characterization and localization using [3H]guanidinoethylmercaptosuccinic acid. Biochimie. 70: 57-64. PMID 3135843 DOI: 10.1016/0300-9084(88)90158-7  0.546
1988 Lynch DR, Venable JC, Snyder SH. Enkephalin convertase in the heart: Similar disposition to atrial natriuretic factor Endocrinology. 122: 2683-2691. PMID 2967176 DOI: 10.1210/Endo-122-6-2683  0.381
1987 D'Amato RJ, Blue ME, Largent BL, Lynch DR, Ledbetter DJ, Molliver ME, Snyder SH. Ontogeny of the serotonergic projection to rat neocortex: transient expression of a dense innervation to primary sensory areas. Proceedings of the National Academy of Sciences of the United States of America. 84: 4322-6. PMID 3473503 DOI: 10.1073/Pnas.84.12.4322  0.36
1987 Lynch DR, Strittmatter SM, Venable JC, Snyder SH. Enkephalin convertase in the gastrointestinal tract an associated organs characterized and localized with [3H]guanidinoethylmercaptosuccinic acid. Endocrinology. 121: 116-26. PMID 3109877 DOI: 10.1210/Endo-121-1-116  0.552
1987 Wilson SK, Lynch DR, Snyder SH. Angiotensin-converting enzyme labeled with [3H]captopril: Tissue localizations and changes in different models of hypertension in the rat Journal of Clinical Investigation. 80: 841-851. PMID 3040809 DOI: 10.1172/Jci113142  0.352
1986 Lynch DR, Strittmatter SM, Venable JC, Snyder SH. Enkephalin convertase: localization to specific neuronal pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1662-75. PMID 3086516 DOI: 10.1523/Jneurosci.06-06-01662.1986  0.563
1986 Strittmatter SM, Lynch DR, Snyder SH. Differential ontogeny of rat brain peptidases: prenatal expression of enkephalin convertase and postnatal development of angiotensin-converting enzyme. Brain Research. 394: 207-15. PMID 3021286 DOI: 10.1016/0165-3806(86)90096-9  0.553
1986 Lynch DR, Snyder SH. Neuropeptides: multiple molecular forms, metabolic pathways, and receptors Annual Review of Biochemistry. 55: 773-799. PMID 3017197 DOI: 10.1146/Annurev.Bi.55.070186.004013  0.403
1986 Lynch DR, Braas KM, Snyder SH. Atrial natriuretic factor receptors in rat kidney, adrenal gland, and brain: autoradiographic localization and fluid balance dependent changes Proceedings of the National Academy of Sciences of the United States of America. 83: 3357-3361. PMID 3010291 DOI: 10.1073/Pnas.83.10.3557  0.406
1986 Strittmatter SM, De Souza EB, Lynch DR, Snyder SH. Angiotensin-converting enzyme localized in the rat pituitary and adrenal glands by [3H]captopril autoradiography. Endocrinology. 118: 1690-9. PMID 3004925 DOI: 10.1210/Endo-118-4-1690  0.539
1985 Strittmatter SM, Lynch DR, De Souza EB, Snyder SH. Enkephalin convertase demonstrated in the pituitary and adrenal gland by [3H]guanidinoethylmercaptosuccinic acid autoradiography: dehydration decreases neurohypophyseal levels. Endocrinology. 117: 1667-74. PMID 3928337 DOI: 10.1210/Endo-117-4-1667  0.551
1984 Lynch DR, Strittmatter SM, Snyder SH. Enkephalin convertase localization by [3H]guanidinoethylmercaptosuccinic acid autoradiography: selective association with enkephalin-containing neurons. Proceedings of the National Academy of Sciences of the United States of America. 81: 6543-7. PMID 6436816 DOI: 10.1073/Pnas.81.20.6543  0.551
1984 Strittmatter SM, Lynch DR, Snyder SH. [3H]guanidinoethylmercaptosuccinic acid binding to tissue homogenates. Selective labeling of enkephalin convertase. The Journal of Biological Chemistry. 259: 11812-7. PMID 6434531  0.418
1984 Whitehouse PJ, Lynch D, Kuhar MJ. Effects of postmortem delay and temperature on neurotransmitter receptor binding in a rat model of the human autopsy process. Journal of Neurochemistry. 43: 553-9. PMID 6330303 DOI: 10.1111/J.1471-4159.1984.Tb00934.X  0.477
Low-probability matches (unlikely to be authored by this person)
2012 Ashley CN, Hoang KD, Lynch DR, Perlman SL, Maria BL. Childhood ataxia: clinical features, pathogenesis, key unanswered questions, and future directions. Journal of Child Neurology. 27: 1095-120. PMID 22859693 DOI: 10.1177/0883073812448840  0.299
2015 Li Y, Polak U, Bhalla AD, Rozwadowska N, Butler JS, Lynch DR, Dent SY, Napierala M. Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1055-65. PMID 25758173 DOI: 10.1038/Mt.2015.41  0.298
2017 Long A, Napierala JS, Polak U, Hauser L, Koeppen AH, Lynch DR, Napierala M. Somatic instability of the expanded GAA repeats in Friedreich's ataxia. Plos One. 12: e0189990. PMID 29261783 DOI: 10.1371/Journal.Pone.0189990  0.295
2007 O'Donnell LA, Agrawal A, Sabnekar P, Dichter MA, Lynch DR, Kolson DL. Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury. Journal of Neurochemistry. 102: 1905-17. PMID 17767704 DOI: 10.1111/J.1471-4159.2007.04645.X  0.294
2019 Weng L, Wang Q, Yu S, Yang X, Lynch DR, Mesaros C, Blair IA. Evaluation of antibodies for western blot analysis of frataxin protein isoforms. Journal of Immunological Methods. PMID 31279523 DOI: 10.1016/J.Jim.2019.07.001  0.294
2009 Tsou AY, Friedman LS, Wilson RB, Lynch DR. Pharmacotherapy for Friedreich ataxia. Cns Drugs. 23: 213-23. PMID 19320530 DOI: 10.2165/00023210-200923030-00003  0.293
2018 Nachun D, Gao F, Isaacs C, Strawser C, Yang Z, Dokuru D, Van Berlo V, Sears R, Farmer J, Perlman S, Lynch DR, Coppola G. Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich's ataxia patients. Human Molecular Genetics. PMID 29790959 DOI: 10.1093/Hmg/Ddy198  0.291
2019 Clark E, Strawser C, Schadt K, Lynch DR. Identification of a novel missense mutation in Friedreich's ataxia -FXN. Annals of Clinical and Translational Neurology. 6: 812-816. PMID 31020006 DOI: 10.1002/Acn3.728  0.291
1990 Lynch DR, Braas KM, Mutton JC, Snyder SH. Carboxypeptidase E (CPE): Immunocytochemical localization in the rat central nervous system and pituitary gland Journal of Neuroscience. 10: 1592-1599. PMID 2332799 DOI: 10.1523/Jneurosci.10-05-01592.1990  0.291
2016 Lin H, Jacobi AA, Anderson SA, Lynch DR. D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability. Frontiers in Cellular Neuroscience. 10: 34. PMID 26941605 DOI: 10.3389/Fncel.2016.00034  0.29
2016 Li Y, Polak U, Clark AD, Bhalla AD, Chen YY, Li J, Farmer J, Seyer L, Lynch D, Butler JS, Napierala M. Establishment and Maintenance of Primary Fibroblast Repositories for Rare Diseases-Friedreich's Ataxia Example. Biopreservation and Biobanking. PMID 27002638 DOI: 10.1089/Bio.2015.0117  0.289
1990 Aberle DR, Gamsu G, Lynch D. Thoracic manifestations of Wegener granulomatosis: diagnosis and course. Radiology. 174: 703-709. PMID 2305053 DOI: 10.1148/Radiology.174.3.2305053  0.289
2018 Jacobi AA, Halawani S, Lynch DR, Lin H. Neuronal serine racemase associates with Disrupted-In-Schizophrenia-1 and DISC1 agglomerates: Implications for schizophrenia. Neuroscience Letters. PMID 30391323 DOI: 10.1016/J.Neulet.2018.10.055  0.287
2017 Napierala JS, Li Y, Lu Y, Lin K, Hauser LA, Lynch DR, Napierala M. Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers. Disease Models & Mechanisms. 10: 1353-1369. PMID 29125828 DOI: 10.1242/Dmm.030536  0.287
2008 Lagier-Tourenne C, Tazir M, López LC, Quinzii CM, Assoum M, Drouot N, Busso C, Makri S, Ali-Pacha L, Benhassine T, Anheim M, Lynch DR, Thibault C, Plewniak F, Bianchetti L, et al. ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. American Journal of Human Genetics. 82: 661-72. PMID 18319074 DOI: 10.1016/J.Ajhg.2007.12.024  0.286
2000 Wilson RB, Lynch DR, Farmer JM, Brooks DG, Fischbeck KH. Increased serum transferrin receptor concentrations in Friedreich ataxia. Annals of Neurology. 47: 659-61. PMID 10805340 DOI: 10.1002/1531-8249(200005)47:5<659::Aid-Ana17>3.0.Co;2-T  0.286
1995 Lynch DR, Lawrence JJ, Lenz S, Anegawa NJ, Dichter M, Pritchett DB. Pharmacological characterization of heterodimeric NMDA receptors composed of NR 1a and 2B subunits: differences with receptors formed from NR 1a and 2A. Journal of Neurochemistry. 64: 1462-8. PMID 7891073 DOI: 10.1046/J.1471-4159.1995.64041462.X  0.282
2012 Evans-Galea MV, Carrodus N, Rowley SM, Corben LA, Tai G, Saffery R, Galati JC, Wong NC, Craig JM, Lynch DR, Regner SR, Brocht AF, Perlman SL, Bushara KO, Gomez CM, et al. FXN methylation predicts expression and clinical outcome in Friedreich ataxia. Annals of Neurology. 71: 487-97. PMID 22522441 DOI: 10.1002/Ana.22671  0.28
2016 Shinnick JE, Schadt K, Strawser C, Wilcox N, Perlman SL, Wilmot GR, Gomez CM, Mathews KD, Yoon G, Zesiewicz T, Hoyle C, Subramony SH, Yiu EM, Delatycki MB, Brocht AF, ... ... Lynch DR, et al. Comorbid Medical Conditions in Friedreich Ataxia: Association With Inflammatory Bowel Disease and Growth Hormone Deficiency. Journal of Child Neurology. PMID 27071470 DOI: 10.1177/0883073816643408  0.28
2003 Connelly T, Farmer JM, Lynch DR, Doty RL. Olfactory dysfunction in degenerative ataxias. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 1435-7. PMID 14570842 DOI: 10.1136/Jnnp.74.10.1435  0.28
2002 Licht DJ, Lynch DR. Juvenile dentatorubral-pallidoluysian atrophy: new clinical features. Pediatric Neurology. 26: 51-4. PMID 11814736 DOI: 10.1016/S0887-8994(01)00346-0  0.28
2017 Strawser C, Schadt K, Hauser L, McCormick A, Wells M, Larkindale J, Lin H, Lynch DR. Pharmacological therapeutics in Friedreich Ataxia: The present state. Expert Review of Neurotherapeutics. PMID 28724340 DOI: 10.1080/14737175.2017.1356721  0.279
2018 Wang Q, Guo L, Strawser CJ, Hauser LA, Hwang WT, Snyder NW, Lynch DR, Mesaros C, Blair IA. Low apolipoprotein A-I levels in Friedreich's ataxia and in frataxin-deficient cells: Implications for therapy. Plos One. 13: e0192779. PMID 29447225 DOI: 10.1371/Journal.Pone.0192779  0.279
2017 Lin H, Magrane J, Clark EM, Halawani SM, Warren N, Rattelle A, Lynch DR. Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia. Disease Models & Mechanisms. 10: 1529-1538. PMID 29259026 DOI: 10.1242/Dmm.030049  0.277
1997 Lynch DR, Chance PF. Inherited peripheral neuropathies Neurologist. 3: 277-292. DOI: 10.1097/00127893-199709000-00001  0.277
2016 Shinnick JE, Isaacs CJ, Vivaldi S, Schadt K, Lynch DR. Friedreich Ataxia and nephrotic syndrome: a series of two patients. Bmc Neurology. 16: 3. PMID 26755195 DOI: 10.1186/S12883-016-0526-2  0.276
2011 Coppola G, Burnett R, Perlman S, Versano R, Gao F, Plasterer H, Rai M, Saccá F, Filla A, Lynch DR, Rusche JR, Gottesfeld JM, Pandolfo M, Geschwind DH. A gene expression phenotype in lymphocytes from Friedreich ataxia patients. Annals of Neurology. 70: 790-804. PMID 22162061 DOI: 10.1002/Ana.22526  0.276
2005 Fink JN, Ortega HG, Reynolds HY, Cormier YF, Fan LL, Franks TJ, Kreiss K, Kunkel S, Lynch D, Quirce S, Rose C, Schleimer RP, Schuyler MR, Selman M, Trout D, et al. Needs and opportunities for research in hypersensitivity pneumonitis. American Journal of Respiratory and Critical Care Medicine. 171: 792-8. PMID 15657460 DOI: 10.1164/Rccm.200409-1205Ws  0.276
2019 Clay A, Hearle P, Schadt K, Lynch DR. New developments in pharmacotherapy for Friedreich ataxia. Expert Opinion On Pharmacotherapy. 1-13. PMID 31311349 DOI: 10.1080/14656566.2019.1639671  0.276
2018 Lynch DR, McCormick A, Schadt K, Kichula E. Pediatric Ataxia: Focus on Chronic Disorders. Seminars in Pediatric Neurology. 25: 54-64. PMID 29735117 DOI: 10.1016/J.Spen.2018.01.001  0.275
2000 McCormack ML, Guttmann RP, Schumann M, Farmer JM, Stolle CA, Campuzano V, Koenig M, Lynch DR. Frataxin point mutations in two patients with Friedreich's ataxia and unusual clinical features. Journal of Neurology, Neurosurgery, and Psychiatry. 68: 661-4. PMID 10766903 DOI: 10.1136/Jnnp.68.5.661  0.275
2014 Burnham EL, Hyzy RC, Paine R, Kelly AM, Quint LE, Lynch D, Curran-Everett D, Moss M, Standiford TJ. Detection of fibroproliferation by chest high-resolution CT scan in resolving ARDS. Chest. 146: 1196-204. PMID 24722949 DOI: 10.1378/Chest.13-2708  0.275
2008 Stolle CA, Frackelton EC, McCallum J, Farmer JM, Tsou A, Wilson RB, Lynch DR. Novel, complex interruptions of the GAA repeat in small, expanded alleles of two affected siblings with late-onset Friedreich ataxia. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 1303-6. PMID 18464277 DOI: 10.1002/Mds.22012  0.275
2019 Puligedda RD, Sharma R, Al-Saleem FH, Kouiavskaia D, Velu AB, Kattala CD, Prendergast GC, Lynch DR, Chumakov K, Dessain SK. Capture and display of antibodies secreted by hybridoma cells enables fluorescent on-cell screening. Mabs. 1-13. PMID 30794061 DOI: 10.1080/19420862.2019.1574520  0.275
2012 Lynch DR, Regner SR, Schadt KA, Friedman LS, Lin KY, St John Sutton MG. Management and therapy for cardiomyopathy in Friedreich's ataxia. Expert Review of Cardiovascular Therapy. 10: 767-77. PMID 22894632 DOI: 10.1586/Erc.12.57  0.274
2012 Regner SR, Lagedrost SJ, Plappert T, Paulsen EK, Friedman LS, Snyder ML, Perlman SL, Mathews KD, Wilmot GR, Schadt KA, Sutton MS, Lynch DR. Analysis of echocardiograms in a large heterogeneous cohort of patients with friedreich ataxia. The American Journal of Cardiology. 109: 401-5. PMID 22078220 DOI: 10.1016/J.Amjcard.2011.09.025  0.272
2002 Lynch DR, Farmer JM, Balcer LJ, Wilson RB. Friedreich ataxia: effects of genetic understanding on clinical evaluation and therapy. Archives of Neurology. 59: 743-7. PMID 12020255 DOI: 10.1001/Archneur.59.5.743  0.272
2014 Strawser CJ, Schadt KA, Lynch DR. Therapeutic approaches for the treatment of Friedreich's ataxia. Expert Review of Neurotherapeutics. 14: 949-57. PMID 25034024 DOI: 10.1586/14737175.2014.939173  0.272
2014 Delatycki MB, Tai G, Corben L, Yiu EM, Evans-Galea MV, Stephenson SE, Gurrin L, Allen KJ, Lynch D, Lockhart PJ. HFE p.C282Y heterozygosity is associated with earlier disease onset in Friedreich ataxia. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 940-3. PMID 24390816 DOI: 10.1002/Mds.25795  0.27
2007 Lynch DR, Braastad CD, Nagan N. Ovarian failure in ataxia with oculomotor apraxia type 2. American Journal of Medical Genetics. Part A. 143: 1775-7. PMID 17593543 DOI: 10.1002/Ajmg.A.31816  0.27
2010 Friedman LS, Farmer JM, Perlman S, Wilmot G, Gomez CM, Bushara KO, Mathews KD, Subramony SH, Ashizawa T, Balcer LJ, Wilson RB, Lynch DR. Measuring the rate of progression in Friedreich ataxia: implications for clinical trial design. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 426-32. PMID 20063431 DOI: 10.1002/Mds.22912  0.27
2012 Regner SR, Wilcox NS, Friedman LS, Seyer LA, Schadt KA, Brigatti KW, Perlman S, Delatycki M, Wilmot GR, Gomez CM, Bushara KO, Mathews KD, Subramony SH, Ashizawa T, Ravina B, ... ... Lynch DR, et al. Friedreich ataxia clinical outcome measures: natural history evaluation in 410 participants. Journal of Child Neurology. 27: 1152-8. PMID 22752494 DOI: 10.1177/0883073812448462  0.27
2003 Lamperti C, Naini A, Hirano M, Vivo DCD, Bertini E, Servidei S, Valeriani M, Lynch D, Banwell B, Berg M, Dubrovsky T, Chiriboga C, Angelini C, Pegoraro E, DiMauro S. Cerebellar ataxia and coenzyme Q10 deficiency Neurology. 60: 1206-1208. PMID 12682339 DOI: 10.1212/01.Wnl.0000055089.39373.Fc  0.269
2014 Lin H, Hsu FC, Baumann BH, Coulter DA, Anderson SA, Lynch DR. Cortical parvalbumin GABAergic deficits with α7 nicotinic acetylcholine receptor deletion: implications for schizophrenia. Molecular and Cellular Neurosciences. 61: 163-75. PMID 24983521 DOI: 10.1016/J.Mcn.2014.06.007  0.268
2002 Lynch DR, Farmer JM, Rochestie D, Balcer LJ. Contrast letter acuity as a measure of visual dysfunction in patients with Friedreich ataxia. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 22: 270-4. PMID 12464730 DOI: 10.1097/00041327-200212000-00003  0.267
2016 Evans CM, Fingerlin TE, Schwarz MI, Lynch D, Kurche J, Warg L, Yang IV, Schwartz DA. Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways. Physiological Reviews. 96: 1567-1591. PMID 27630174 DOI: 10.1152/Physrev.00004.2016  0.265
2008 Maletkovic J, Schiffmann R, Gorospe JR, Gordon ES, Mintz M, Hoffman EP, Alper G, Lynch DR, Singhal BS, Harding C, Amartino H, Brown CM, Chan A, Renaud D, Geraghty M, et al. Genetic and clinical heterogeneity in eIF2B-related disorder. Journal of Child Neurology. 23: 205-15. PMID 18263758 DOI: 10.1177/0883073807308705  0.265
2012 Meier T, Perlman SL, Rummey C, Coppard NJ, Lynch DR. Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study. Journal of Neurology. 259: 284-91. PMID 21779958 DOI: 10.1007/S00415-011-6174-Y  0.264
2013 Metz G, Coppard N, Cooper JM, Delatycki MB, Dürr A, Di Prospero NA, Giunti P, Lynch DR, Schulz JB, Rummey C, Meier T. Rating disease progression of Friedreich's ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database. Brain : a Journal of Neurology. 136: 259-68. PMID 23365101 DOI: 10.1093/Brain/Aws309  0.264
2002 Lynch DR, Farmer J. Practical approaches to neurogenetic disease. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 22: 297-304. PMID 12464734 DOI: 10.1097/00041327-200212000-00007  0.264
2017 Clark E, Butler JS, Isaacs CJ, Napierala M, Lynch DR. Selected missense mutations impair frataxin processing in Friedreich ataxia. Annals of Clinical and Translational Neurology. 4: 575-584. PMID 28812047 DOI: 10.1002/Acn3.433  0.263
2006 Robin NH, Taylor CJ, McDonald-McGinn DM, Zackai EH, Bingham P, Collins KJ, Earl D, Gill D, Granata T, Guerrini R, Katz N, Kimonis V, Lin JP, Lynch DR, Mohammed SN, et al. Polymicrogyria and deletion 22q11.2 syndrome: window to the etiology of a common cortical malformation. American Journal of Medical Genetics. Part A. 140: 2416-25. PMID 17036343 DOI: 10.1002/Ajmg.A.31443  0.263
2004 Bruno MK, Hallett M, Gwinn-Hardy K, Sorensen B, Considine E, Tucker S, Lynch DR, Mathews KD, Swoboda KJ, Harris J, Soong BW, Ashizawa T, Jankovic J, Renner D, Fu YH, et al. Clinical evaluation of idiopathic paroxysmal kinesigenic dyskinesia: new diagnostic criteria. Neurology. 63: 2280-7. PMID 15623687 DOI: 10.1212/01.Wnl.0000147298.05983.50  0.263
2005 Lynch DR, Farmer JM, Wilson RL, Balcer LJ. Performance measures in Friedreich ataxia: potential utility as clinical outcome tools. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 777-82. PMID 15747359 DOI: 10.1002/Mds.20449  0.263
2008 Epstein E, Farmer JM, Tsou A, Perlman S, Subramony SH, Gomez CM, Ashizawa T, Wilmot GR, Mathews K, Wilson RB, Balcer LJ, Lynch DR. Health related quality of life measures in Friedreich Ataxia. Journal of the Neurological Sciences. 272: 123-8. PMID 18571673 DOI: 10.1016/J.Jns.2008.05.009  0.262
2020 Rummey C, Farmer JM, Lynch DR. Predictors of loss of ambulation in Friedreich's ataxia. Eclinicalmedicine. 18: 100213. PMID 31938785 DOI: 10.1016/J.Eclinm.2019.11.006  0.262
2013 McDonald-McGinn DM, Fahiminiya S, Revil T, Nowakowska BA, Suhl J, Bailey A, Mlynarski E, Lynch DR, Yan AC, Bilaniuk LT, Sullivan KE, Warren ST, Emanuel BS, Vermeesch JR, Zackai EH, et al. Hemizygous mutations in SNAP29 unmask autosomal recessive conditions and contribute to atypical findings in patients with 22q11.2DS. Journal of Medical Genetics. 50: 80-90. PMID 23231787 DOI: 10.1136/Jmedgenet-2012-101320  0.261
2016 Raoof S, Bondalapati P, Vydyula R, Ryu J, Gupta N, Raoof S, Galvin J, Rosen MJ, Lynch D, Travis W, Mehta S, Lazzaro R, Naidich D. Cystic Lung Diseases: Algorithmic Approach. Chest. PMID 27180915 DOI: 10.1016/J.Chest.2016.04.026  0.261
1995 Lynch DR, McDonald-McGinn DM, Zackai EH, Emanuel BS, Driscoll DA, Whitaker LA, Fischbeck KH. Cerebellar atrophy in a patient with velocardiofacial syndrome. Journal of Medical Genetics. 32: 561-3. PMID 7562973 DOI: 10.1136/Jmg.32.7.561  0.26
2010 Singh A, Epstein E, Myers LM, Farmer JM, Lynch DR. Clinical measures of dysarthria in Friedreich Ataxia. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 108-11. PMID 20014117 DOI: 10.1002/Mds.22776  0.26
2012 Martelli A, Friedman LS, Reutenauer L, Messaddeq N, Perlman SL, Lynch DR, Fedosov K, Schulz JB, Pandolfo M, Puccio H. Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia. Disease Models & Mechanisms. 5: 860-9. PMID 22736457 DOI: 10.1242/Dmm.009829  0.259
2019 Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros C, Lynch DR, Blair IA. Correction to Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia. Analytical Chemistry. PMID 30676739 DOI: 10.1021/Acs.Analchem.9B00141  0.259
2006 O'Donnell LA, Agrawal A, Jordan-Sciutto KL, Dichter MA, Lynch DR, Kolson DL. Human immunodeficiency virus (HIV)-induced neurotoxicity: roles for the NMDA receptor subtypes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 981-90. PMID 16421318 DOI: 10.1523/Jneurosci.4617-05.2006  0.259
2017 Han M, Tayob N, Kim V, Murray S, Barr RG, Rennard S, Woodruff P, Cooper C, Kanner R, Bleecker E, Couper D, Hersh C, Wendt C, Dransfield M, Curtis J, ... ... Lynch D, et al. Association between emphysema, exacerbations and mortality in the COPDGene and SPIROMICS cohorts European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Oa1496  0.258
2018 Rummey C, Kichula E, Lynch DR. Clinical trial design for Friedreich ataxia - Where are we now and what do we need? Expert Opinion On Orphan Drugs. 6: 219-230. DOI: 10.1080/21678707.2018.1449638  0.258
2018 Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Mesaros C, Lynch DR, Blair IA. Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes. Scientific Reports. 8: 17043. PMID 30451920 DOI: 10.1038/S41598-018-35346-Y  0.258
2002 Lynch DR, Lech G, Farmer JM, Balcer LJ, Bank W, Chance B, Wilson RB. Near infrared muscle spectroscopy in patients with Friedreich's ataxia. Muscle & Nerve. 25: 664-73. PMID 11994959 DOI: 10.1002/Mus.10077  0.257
1997 McDonald-McGinn DM, LaRossa D, Goldmuntz E, Sullivan K, Eicher P, Gerdes M, Moss E, Wang P, Solot C, Schultz P, Lynch D, Bingham P, Keenan G, Weinzimer S, Ming JE, et al. The 22q11.2 deletion: screening, diagnostic workup, and outcome of results; report on 181 patients. Genetic Testing. 1: 99-108. PMID 10464633 DOI: 10.1089/Gte.1997.1.99  0.257
2012 Lee HY, Huang Y, Bruneau N, Roll P, Roberson ED, Hermann M, Quinn E, Maas J, Edwards R, Ashizawa T, Baykan B, Bhatia K, Bressman S, Bruno MK, Brunt ER, ... ... Lynch DR, et al. Mutations in the gene PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions. Cell Reports. 1: 2-12. PMID 22832103 DOI: 10.1016/J.Celrep.2011.11.001  0.257
2007 Friedlander AL, Lynch D, Dyar LA, Bowler RP. Phenotypes of chronic obstructive pulmonary disease. Copd. 4: 355-84. PMID 18027163 DOI: 10.1080/15412550701629663  0.257
2015 De Andrade J, Schwarz M, Collard HR, Gentry-Bumpass T, Colby T, Lynch D, Kaner RJ, Zisman DA, Chapman J, Olman M, Lubell S, Morrison LD, Steele MP, Haram T, Roman J, ... ... Lynch DA, et al. The idiopathic pulmonary fibrosis clinical research network (IPFnet): Diagnostic and adjudication processes Chest. 148: 1034-1042. DOI: 10.1378/Chest.14-2889  0.256
2008 Raghu G, Nicholson AG, Lynch D. The classification, natural history and radiological/histological appearance of idiopathic pulmonary fibrosis and the other idiopathic interstitial pneumonias European Respiratory Review. 17: 108-115. DOI: 10.1183/09059180.00010902  0.254
2015 Galea CA, Huq A, Lockhart PJ, Tai G, Corben LA, Yiu EM, Gurrin LC, Lynch DR, Gelbard S, Durr A, Pousset F, Parkinson M, Labrum R, Giunti P, Perlman SL, et al. Compound heterozygous FXN mutations and clinical outcome in Friedreich ataxia. Annals of Neurology. PMID 26704351 DOI: 10.1002/Ana.24595  0.254
2009 Goldin J, Elashoff R, Kim HJ, Yan X, Lynch D, Strollo D, Roth MD, Clements P, Furst DE, Khanna D, Vasunilashorn S, Li G, Tashkin DP. Treatment of scleroderma-interstitial lung disease with cyclophosphamide is associated with less progressive fibrosis on serial thoracic high-resolution CT scan than placebo: findings from the scleroderma lung study. Chest. 136: 1333-40. PMID 19892673 DOI: 10.1378/Chest.09-0108  0.254
2017 Lin H, Magrane J, Rattelle A, Stepanova A, Galkin A, Clark EM, Dong YN, Halawani SM, Lynch DR. Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia. Disease Models & Mechanisms. 10: 1343-1352. PMID 29125827 DOI: 10.1242/Dmm.030502  0.254
2008 Friedman LS, Schadt KA, Wilson RB, Lynch DR. Efficacy and safety of idebenone in the treatment of Friedreich ataxia: A review of early results and future prospects Future Neurology. 3: 375-384. DOI: 10.2217/14796708.3.4.375  0.253
2020 Tamaroff J, Dedio A, Wade KL, Rummey C, Pinney SE, Lynch D, Kelly A, Mccormack S. 1569-P: Prevalence, Risk, and Management of Diabetes in Friedreich’s Ataxia Diabetes. 69. DOI: 10.2337/Db20-1569-P  0.253
2016 Patel M, Isaacs CJ, Seyer L, Brigatti K, Gelbard S, Strawser C, Foerster D, Shinnick J, Schadt K, Yiu EM, Delatycki MB, Perlman S, Wilmot GR, Zesiewicz T, Mathews K, ... ... Lynch DR, et al. Progression of Friedreich ataxia: quantitative characterization over 5 years. Annals of Clinical and Translational Neurology. 3: 684-694. PMID 27648458 DOI: 10.1002/Acn3.332  0.252
2015 Isaacs CJ, Shinnick JE, Schadt K, Lynch DR, Lin KY. Prospects of gene and cell therapy for managing cardiac complications in Friedreich ataxia Expert Opinion On Orphan Drugs. 3: 1183-1196. DOI: 10.1517/21678707.2015.1083854  0.252
2014 Kim V, Davey A, Comellas AP, Han MK, Washko G, Martinez CH, Lynch D, Lee JH, Silverman EK, Crapo JD, Make BJ, Criner GJ. Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study. Respiratory Research. 15: 52. PMID 24766722 DOI: 10.1186/1465-9921-15-52  0.252
2015 Murphy AG, Lynch D, Kelly RJ. State of the art management of metastatic gastroesophageal cancer. Annals of Translational Medicine. 3: 236. PMID 26539453 DOI: 10.3978/J.Issn.2305-5839.2015.09.19  0.252
2016 Tsuchiya Y, Lynch D, Johkoh T, Colby T, Fukuoka J, Egashira R, Sumikawa H, Okada T, Swigris J, Solomon J. Usual interstitial pneumonia preceding rheumatoid arthritis: Clinical, imaging, and histopathologic features European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa4887  0.25
2014 Raghu G, Lynch D, Godwin JD, Webb R, Colby TV, Leslie KO, Behr J, Brown KK, Egan JJ, Flaherty KR, Martinez FJ, Wells AU, Shao L, Zhou H, Pedersen PS, et al. Diagnosis of idiopathic pulmonary fibrosis with high-resolution CT in patients with little or no radiological evidence of honeycombing: secondary analysis of a randomised, controlled trial. The Lancet. Respiratory Medicine. 2: 277-84. PMID 24717624 DOI: 10.1016/S2213-2600(14)70011-6  0.25
2004 Kao A, Mariani J, McDonald-McGinn DM, Maisenbacher MK, Brooks-Kayal AR, Zackai EH, Lynch DR. Increased prevalence of unprovoked seizures in patients with a 22q11.2 deletion. American Journal of Medical Genetics. Part A. 129: 29-34. PMID 15266612 DOI: 10.1002/Ajmg.A.30133  0.249
2014 Hobbs S, Lynch D. The idiopathic interstitial pneumonias: an update and review. Radiologic Clinics of North America. 52: 105-20. PMID 24267713 DOI: 10.1016/J.Rcl.2013.08.001  0.248
2013 Friedman LS, Schadt KA, Regner SR, Mark GE, Lin KY, Sciascia T, St John Sutton M, Willi S, Lynch DR. Elevation of serum cardiac troponin I in a cross-sectional cohort of asymptomatic subjects with Friedreich ataxia. International Journal of Cardiology. 167: 1622-4. PMID 22633670 DOI: 10.1016/J.Ijcard.2012.04.159  0.248
2001 Hunninghake GW, Zimmerman MB, Schwartz DA, King TE, Lynch J, Hegele R, Waldron J, Colby T, Müller N, Lynch D, Galvin J, Gross B, Hogg J, Toews G, Helmers R, et al. Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 164: 193-6. PMID 11463586 DOI: 10.1164/Ajrccm.164.2.2101090  0.247
1989 Wilson SK, Lynch DR, Ladenson PW. Angiotensin II and atrial natriuretic factor-binding sites in various tissues in hypertension: Comparative receptor localization and changes in different hypertension models in the rat Endocrinology. 124: 2799-2808. PMID 2542000 DOI: 10.1210/Endo-124-6-2799  0.247
2017 McCormick A, Shinnick J, Schadt K, Rodriguez R, Addonizio L, Hirano M, Perlman S, Lin KY, Lynch DR. Cardiac transplantation in Friedreich Ataxia: Extended follow-up. Journal of the Neurological Sciences. PMID 28109580 DOI: 10.1016/J.Jns.2017.01.027  0.246
2019 Blair IA, Farmer J, Hersch S, Larkindale J, Lynch DR, Napierala J, Napierala M, Payne RM, Subramony SH. The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting. Future Science Oa. 5: FSO398. PMID 31285843 DOI: 10.2144/Fsoa-2019-0026  0.246
2009 Zesiewicz TA, Sullivan KL, Gooch CL, Lynch DR. Subjective improvement in proprioception in 2 patients with atypical Friedreich ataxia treated with varenicline (Chantix). Journal of Clinical Neuromuscular Disease. 10: 191-3. PMID 19494730 DOI: 10.1097/Cnd.0B013E3181910074  0.246
2013 Seyer LA, Galetta K, Wilson J, Sakai R, Perlman S, Mathews K, Wilmot GR, Gomez CM, Ravina B, Zesiewicz T, Bushara KO, Subramony SH, Ashizawa T, Delatycki MB, Brocht A, ... ... Lynch DR, et al. Analysis of the visual system in Friedreich ataxia. Journal of Neurology. 260: 2362-9. PMID 23775342 DOI: 10.1007/S00415-013-6978-Z  0.246
2011 Lagedrost SJ, Sutton MS, Cohen MS, Satou GM, Kaufman BD, Perlman SL, Rummey C, Meier T, Lynch DR. Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA). American Heart Journal. 161: 639-645.e1. PMID 21392622 DOI: 10.1016/J.Ahj.2010.10.038  0.245
1999 Quaife RA, Lynch D, Badesch DB, Voelkel NF, Lowes BD, Robertson AD, Bristow MR. Right ventricular phenotypic characteristics in subjects with primary pulmonary hypertension or idiopathic dilated cardiomyopathy Journal of Cardiac Failure. 5: 46-54. PMID 10194660 DOI: 10.1016/S1071-9164(99)90024-6  0.245
2015 Li Y, Lu Y, Polak U, Lin K, Shen J, Farmer J, Seyer L, Bhalla AD, Rozwadowska N, Lynch DR, Butler JS, Napierala M. Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus. Human Molecular Genetics. PMID 26401053 DOI: 10.1093/Hmg/Ddv397  0.245
2017 McCormick A, Farmer J, Perlman S, Delatycki M, Wilmot G, Matthews K, Yoon G, Hoyle C, Subramony SH, Zesiewicz T, Lynch DR, McCormack SE. Impact of diabetes in the Friedreich ataxia clinical outcome measures study. Annals of Clinical and Translational Neurology. 4: 622-631. PMID 28904984 DOI: 10.1002/Acn3.439  0.244
2004 Bearden CE, Jawad AF, Lynch DR, Sokol S, Kanes SJ, McDonald-McGinn DM, Saitta SC, Harris SE, Moss E, Wang PP, Zackai E, Emanuel BS, Simon TJ. Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome. The American Journal of Psychiatry. 161: 1700-2. PMID 15337663 DOI: 10.1176/Appi.Ajp.161.9.1700  0.244
2003 Lynch DR, Mozley PD, Sokol S, Maas NM, Balcer LJ, Siderowf AD. Lack of effect of polymorphisms in dopamine metabolism related genes on imaging of TRODAT-1 in striatum of asymptomatic volunteers and patients with Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 804-12. PMID 12815660 DOI: 10.1002/Mds.10430  0.244
2015 Wells M, Seyer L, Schadt K, Lynch DR. IFN-γ for Friedreich ataxia: present evidence. Neurodegenerative Disease Management. 5: 497-504. PMID 26634868 DOI: 10.2217/Nmt.15.52  0.244
2007 Babady NE, Carelle N, Wells RD, Rouault TA, Hirano M, Lynch DR, Delatycki MB, Wilson RB, Isaya G, Puccio H. Advancements in the pathophysiology of Friedreich's Ataxia and new prospects for treatments. Molecular Genetics and Metabolism. 92: 23-35. PMID 17596984 DOI: 10.1016/J.Ymgme.2007.05.009  0.243
2019 Lynch DR, Farmer J, Hauser L, Blair IA, Wang QQ, Mesaros C, Snyder N, Boesch S, Chin M, Delatycki MB, Giunti P, Goldsberry A, Hoyle C, McBride MG, Nachbauer W, et al. Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia. Annals of Clinical and Translational Neurology. 6: 15-26. PMID 30656180 DOI: 10.1002/Acn3.660  0.243
1997 Lynch DR, Hara H, Yum SW, Chance PF, Scherer SS, Bird SJ, Fischbeck KH. Autosomal dominant transmission of Dejerine-Sottas disease (HMSN III). Neurology. 49: 601-3. PMID 9270606 DOI: 10.1212/Wnl.49.2.601  0.243
2016 Bhalla AD, Khodadadi-Jamayran A, Li Y, Lynch DR, Napierala M. Deep sequencing of mitochondrial genomes reveals increased mutation load in Friedreich's ataxia. Annals of Clinical and Translational Neurology. 3: 523-536. PMID 27386501 DOI: 10.1002/Acn3.322  0.243
2012 Schadt KA, Friedman LS, Regner SR, Mark GE, Lynch DR, Lin KY. Cross-sectional analysis of electrocardiograms in a large heterogeneous cohort of Friedreich ataxia subjects. Journal of Child Neurology. 27: 1187-92. PMID 22752487 DOI: 10.1177/0883073812448461  0.242
2016 Panzer JA, Anand R, Dalmau J, Lynch DR. Corrigendum to "Antibodies to dendritic neuronal surface antigens in opsoclonus myoclonus ataxia syndrome" [J. Neuroimmunol. 286 (2015) 86-92]. Journal of Neuroimmunology. PMID 27266593 DOI: 10.1016/J.Jneuroim.2016.05.001  0.242
2013 Lynch DR, Pandolfo M, Schulz JB, Perlman S, Delatycki MB, Payne RM, Shaddy R, Fischbeck KH, Farmer J, Kantor P, Raman SV, Hunegs L, Odenkirchen J, Miller K, Kaufmann P. Common data elements for clinical research in Friedreich's ataxia. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 190-5. PMID 23239403 DOI: 10.1002/Mds.25201  0.242
2020 Afsharian P, Nolan-Kenney R, Lynch AE, Balcer LJ, Lynch DR. Correlation of Visual Quality of Life With Clinical and Visual Status in Friedreich Ataxia. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. PMID 31977662 DOI: 10.1097/Wno.0000000000000878  0.241
2020 Zaoui P, Chin M, Delatycki M, Giunti P, Goldsberry A, Meyer C, O'Grady M, Perlman S, Subramony SH, Zesiewicz T, Lynch D. P0222Kidney Effects In The Moxie Trial: A Study Of Omaveloxolone In Patients With Friedrich'S Ataxia Nephrology Dialysis Transplantation. 35. DOI: 10.1093/Ndt/Gfaa142.P0222  0.241
2005 Subramony SH, May W, Lynch D, Gomez C, Fischbeck K, Hallett M, Taylor P, Wilson R, Ashizawa T. Measuring Friedreich ataxia: Interrater reliability of a neurologic rating scale Neurology. 64: 1261-1262. PMID 15824358 DOI: 10.1212/01.Wnl.0000156802.15466.79  0.24
2007 Flaherty KR, Andrei AC, King TE, Raghu G, Colby TV, Wells A, Bassily N, Brown K, du Bois R, Flint A, Gay SE, Gross BH, Kazerooni EA, Knapp R, Louvar E, ... Lynch D, et al. Idiopathic interstitial pneumonia: do community and academic physicians agree on diagnosis? American Journal of Respiratory and Critical Care Medicine. 175: 1054-60. PMID 17255566 DOI: 10.1164/Rccm.200606-833Oc  0.24
2012 Mahishi LH, Hart RP, Lynch DR, Ratan RR. miR-886-3p levels are elevated in Friedreich ataxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9369-73. PMID 22764244 DOI: 10.1523/Jneurosci.0059-12.2012  0.24
2010 Lynch DR, Perlman SL, Meier T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Archives of Neurology. 67: 941-7. PMID 20697044 DOI: 10.1001/Archneurol.2010.168  0.239
2008 Myers LM, Lynch DR, Farmer JM, Friedman LS, Lawson JA, Wilson RB. Urinary isoprostanes in Friedreich ataxia: lack of correlation with disease features. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 1920-2. PMID 18671287 DOI: 10.1002/Mds.22038  0.238
2011 Tsou AY, Paulsen EK, Lagedrost SJ, Perlman SL, Mathews KD, Wilmot GR, Ravina B, Koeppen AH, Lynch DR. Mortality in Friedreich ataxia. Journal of the Neurological Sciences. 307: 46-9. PMID 21652007 DOI: 10.1016/J.Jns.2011.05.023  0.237
2018 Zesiewicz T, Salemi JL, Perlman S, Sullivan KL, Shaw JD, Huang Y, Isaacs C, Gooch C, Lynch DR, Klein MB. Double-blind, randomized and controlled trial of EPI-743 in Friedreich's ataxia. Neurodegenerative Disease Management. PMID 30051753 DOI: 10.2217/Nmt-2018-0013  0.237
2015 Hardin M, Foreman M, Dransfield MT, Hansel N, Han MK, Cho MH, Bhatt SP, Ramsdell J, Lynch D, Curtis JL, Silverman EK, Washko G, DeMeo D. Sex-specific features of emphysema among current and former smokers with COPD. The European Respiratory Journal. PMID 26541532 DOI: 10.1183/13993003.00996-2015  0.237
2020 Rummey C, Zesiewicz TA, Perez-Lloret S, Farmer JM, Pandolfo M, Lynch DR. Test-retest reliability of the Friedreich's ataxia rating scale. Annals of Clinical and Translational Neurology. PMID 32779859 DOI: 10.1002/Acn3.51118  0.237
2019 Marty B, Naeije G, Bourguignon M, Wens V, Jousmäki V, Lynch DR, Gaetz W, Goldman S, Hari R, Pandolfo M, De Tiège X. Evidence for genetically determined degeneration of proprioceptive tracts in Friedreich ataxia. Neurology. PMID 31197032 DOI: 10.1212/Wnl.0000000000007750  0.236
2019 Patel M, Schadt K, McCormick A, Isaacs C, Dong YN, Lynch DR. Open label Pilot Study of Oral Methylprednisolone for the Treatment of Patients with Friedreich Ataxia. Muscle & Nerve. PMID 31206761 DOI: 10.1002/Mus.26610  0.236
2008 Myers L, Farmer JM, Wilson RB, Friedman L, Tsou A, Perlman SL, Subramony SH, Gomez CM, Ashizawa T, Wilmot GR, Mathews KD, Balcer LJ, Lynch DR. Antioxidant use in Friedreich ataxia. Journal of the Neurological Sciences. 267: 174-6. PMID 17988688 DOI: 10.1016/J.Jns.2007.10.008  0.235
2014 Black-Shinn JL, Kinney GL, Wise AL, Regan EA, Make B, Krantz MJ, Barr RG, Murphy JR, Lynch D, Silverman EK, Crapo JD, Hokanson JE. Cardiovascular disease is associated with COPD severity and reduced functional status and quality of life. Copd. 11: 546-51. PMID 24831864 DOI: 10.3109/15412555.2014.898029  0.235
2012 Demoruelle K, Weisman M, Harrington A, Derber L, Kolfenbach J, Striebich C, Pedraza I, Lynch D, Sachs P, Petersen B, Strickland C, Norris J, Holers VM, Deane K. Lung abnormalities in subjects with elevations of rheumatoid arthritis-related autoantibodies without arthritis by examination and imaging suggest the lung is an early and perhaps initiating site of inflammation in rheumatoid arthritis Annals of the Rheumatic Diseases. 71: A25.1-A25. DOI: 10.1136/Annrheumdis-2011-201231.16  0.235
2005 Greenbaum EA, Graves CL, Mishizen-Eberz AJ, Lupoli MA, Lynch DR, Englander SW, Axelsen PH, Giasson BI. The E46K mutation in alpha-synuclein increases amyloid fibril formation. The Journal of Biological Chemistry. 280: 7800-7. PMID 15632170 DOI: 10.1074/Jbc.M411638200  0.235
2006 Lynch DR, Farmer JM, Tsou AY, Perlman S, Subramony SH, Gomez CM, Ashizawa T, Wilmot GR, Wilson RB, Balcer LJ. Measuring Friedreich ataxia: complementary features of examination and performance measures. Neurology. 66: 1711-6. PMID 16769945 DOI: 10.1212/01.Wnl.0000218155.46739.90  0.235
2018 Lin H, Magrane J, Rattelle A, Stepanova A, Galkin A, Clark EM, Dong YN, Halawani SM, Lynch DR. Correction: Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia (doi: 10.1242/dmm.030502). Disease Models & Mechanisms. 11. PMID 29419392 DOI: 10.1242/Dmm.033415  0.235
2005 Bearden CE, Jawad AF, Lynch DR, Monterossso JR, Sokol S, McDonald-McGinn DM, Saitta SC, Harris SE, Moss E, Wang PP, Zackai E, Emanuel BS, Simon TJ. Effects of COMT genotype on behavioral symptomatology in the 22q11.2 Deletion Syndrome. Child Neuropsychology : a Journal On Normal and Abnormal Development in Childhood and Adolescence. 11: 109-17. PMID 15846854 DOI: 10.1080/09297040590911239  0.235
1998 Wilson RB, Lynch DR, Fischbeck KH. Normal serum iron and ferritin concentrations in patients with Friedreich's ataxia. Annals of Neurology. 44: 132-4. PMID 9667602 DOI: 10.1002/Ana.410440121  0.234
1993 Welsh CH, Wagner PD, Reeves JT, Lynch D, Cink TM, Armstrong J, Malconian MK, Rock PB, Houston CS. Operation Everest. II: Spirometric and radiographic changes in acclimatized humans at simulated high altitudes. The American Review of Respiratory Disease. 147: 1239-44. PMID 8484637 DOI: 10.1164/Ajrccm/147.5.1239  0.234
2020 Moll M, Sakornsakolpat P, Shrine N, Hobbs BD, DeMeo DL, John C, Guyatt AL, McGeachie MJ, Gharib SA, Obeidat M, Lahousse L, Wijnant SRA, Brusselle G, Meyers DA, Bleecker ER, ... ... Lynch D, et al. Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. The Lancet. Respiratory Medicine. 8: 696-708. PMID 32649918 DOI: 10.1016/S2213-2600(20)30101-6  0.234
2017 Martinez C, Hatt C, Labaki W, Curtis J, Kim V, Bhatt S, Diaz A, Lynch D, Hoffman E, Galban C, Ross B, Kazerooni E, Martinez F, Han M. Lung core-predominant emphysema is associated with higher symptom burden in COPD: analysis of the COPDGene cohort European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Oa508  0.233
2009 Zhu M, Ajdić D, Liu Y, Lynch D, Merritt J, Banas JA. Role of the Streptococcus mutans irvA gene in GbpC-independent, dextran-dependent aggregation and biofilm formation. Applied and Environmental Microbiology. 75: 7037-43. PMID 19783751 DOI: 10.1128/Aem.01015-09  0.233
2014 Wittlieb-Weber C, Rossano J, Lynch D, Lin K. Heart Failure Burden In Children And Adults With Friedreich Ataxia Journal of the American College of Cardiology. 63. DOI: 10.1016/S0735-1097(14)60835-4  0.233
1996 Vincent MS, Roessner K, Lynch D, Wilson D, Cooper SM, Tschopp J, Sigal LH, Budd RC. Apoptosis of Fas(high) CD4+ synovial T cells by Borrelia-reactive fas- ligand(high) γδ T cells in lyme arthritis Journal of Experimental Medicine. 184: 2109-2117. PMID 8976167 DOI: 10.1084/Jem.184.6.2109  0.233
2014 St John Sutton M, Ky B, Regner SR, Schadt K, Plappert T, He J, D'Souza B, Lynch DR. Longitudinal strain in Friedreich Ataxia: a potential marker for early left ventricular dysfunction. Echocardiography (Mount Kisco, N.Y.). 31: 50-7. PMID 23834395 DOI: 10.1111/Echo.12287  0.233
1990 Takimoto CH, Lynch D, Stulbarg MS. Pulmonary infiltrates associated with sulindac therapy. Chest. 97: 230-232. PMID 2295243 DOI: 10.1378/Chest.97.1.230  0.232
2011 Aberle DR, Berg CD, Black WC, Church TR, Fagerstrom RM, Galen B, Gareen IF, Gatsonis C, Goldin J, Gohagan JK, Hillman B, Jaffe C, Kramer BS, Lynch D, et al. The National Lung Screening Trial: overview and study design. Radiology. 258: 243-53. PMID 21045183 DOI: 10.1148/Radiol.10091808  0.232
2016 Yang Y, Zhang L, Lynch DR, Lukas T, Ahmeti K, Sleiman PM, Ryan E, Schadt KA, Newman JH, Deng HX, Siddique N, Siddique T. Compound heterozygote mutations in SPG7 in a family with adult-onset primary lateral sclerosis. Neurology. Genetics. 2: e60. PMID 27123479 DOI: 10.1212/Nxg.0000000000000060  0.232
1989 Gamsu G, Aberle DR, Lynch D. Computed tomography in the diagnosis of asbestos-related thoracic disease. Journal of Thoracic Imaging. 4: 61-67. PMID 2643716 DOI: 10.1097/00005382-198901000-00012  0.231
2013 Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, et al. Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nature Genetics. 45: 613-20. PMID 23583980 DOI: 10.1038/Ng.2609  0.231
2020 Clay A, Obrochta KM, Soon RK, Russell CB, Lynch DR. Neurofilament light chain as a potential biomarker of disease status in Friedreich ataxia. Journal of Neurology. PMID 32385683 DOI: 10.1007/S00415-020-09868-3  0.23
2016 DeBrosse C, Nanga RP, Wilson N, D'Aquilla K, Elliott M, Hariharan H, Yan F, Wade K, Nguyen S, Worsley D, Parris-Skeete C, McCormick E, Xiao R, Cunningham ZZ, Fishbein L, ... ... Lynch DR, et al. Muscle oxidative phosphorylation quantitation using creatine chemical exchange saturation transfer (CrCEST) MRI in mitochondrial disorders. Jci Insight. 1: e88207. PMID 27812541 DOI: 10.1172/Jci.Insight.88207  0.229
2020 Misiorek JO, Schreiber AM, Urbanek-Trzeciak MO, Jazurek-Ciesiołka M, Hauser LA, Lynch DR, Napierala JS, Napierala M. A Comprehensive Transcriptome Analysis Identifies FXN and BDNF as Novel Targets of miRNAs in Friedreich's Ataxia Patients. Molecular Neurobiology. PMID 32291635 DOI: 10.1007/S12035-020-01899-1  0.229
2012 Lee H, Jin GY, Han YM, Chung GH, Lee YC, Kwon KS, Lynch D. Comparison of survival rate in primary non-small-cell lung cancer among elderly patients treated with radiofrequency ablation, surgery, or chemotherapy. Cardiovascular and Interventional Radiology. 35: 343-50. PMID 21626257 DOI: 10.1007/S00270-011-0194-Y  0.229
2011 Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK, Coxson H, Edwards L, Knobil K, ... ... Lynch D, et al. Genome-wide association study of smoking behaviours in patients with COPD Thorax. 66: 894-902. PMID 21685187 DOI: 10.1136/Thoraxjnl-2011-200154  0.229
2019 Vestal BE, Carlson NE, Estépar RSJ, Fingerlin T, Ghosh D, Kechris K, Lynch D. Using a spatial point process framework to characterize lung computed tomography scans. Spatial Statistics. 29: 243-267. PMID 31750077 DOI: 10.1016/J.Spasta.2018.12.003  0.229
2016 Salisbury M, Xia M, Murray S, Lynch D, VanBeek E, Kazerooni E, Guo J, Hoffman E, Flaherty K. P064 Association of Adaptive Multiple Features Method Measures of Fibrosis with Outcomes in Idiopathic Pulmonary Fibrosis Qjm: An International Journal of Medicine. 109. DOI: 10.1093/Qjmed/Hcw124.037  0.228
2013 Burnham EL, Hyzy RC, Paine R, Coley C, Kelly AM, Quint LE, Lynch D, Janssen WJ, Moss M, Standiford TJ. Chest CT features are associated with poorer quality of life in acute lung injury survivors. Critical Care Medicine. 41: 445-56. PMID 23263616 DOI: 10.1097/Ccm.0B013E31826A5062  0.228
2019 Lynch DR, Hauser L, McCormick A, Wells M, Dong YN, McCormack S, Schadt K, Perlman S, Subramony SH, Mathews KD, Brocht A, Ball J, Perdok R, Grahn A, Vescio T, et al. Randomized, double-blind, placebo-controlled study of interferon- 1b in Friedreich Ataxia. Annals of Clinical and Translational Neurology. 6: 546-553. PMID 30911578 DOI: 10.1002/Acn3.731  0.227
1996 Lynch DR, Gallagher MJ. Inhibition of N-methyl-D-aspartate receptors by haloperidol: Developmental and pharmacological characterization in native and recombinant receptors Journal of Pharmacology and Experimental Therapeutics. 279: 154-161. PMID 8858988  0.225
2015 Lin KY, Lynch D, O’Connor MJ, Rossano J. Risk of Heart Failure and Death Among Patients With Friedreich Ataxia Admitted for Non-Cardiac Etiologies Journal of Heart and Lung Transplantation. 34. DOI: 10.1016/J.Healun.2015.01.508  0.225
2011 Huie T, Collard H, Solomon J, Sahin H, Woods A, Kinder B, Curran-Everett D, Lynch D, Fischer A, Brown K. Serologies and Chest CT Findings Predict Prognosis in Interstitial Lung Disease Chest. 140: 992. DOI: 10.1378/Chest.1120097  0.224
2016 Isaacs CJ, Brigatti KW, Kucheruk O, Ratcliffe S, Sciascia T, McCormack SE, Willi SM, Lynch DR. Effects of Genetic Severity on Glucose Homeostasis in Friedreich Ataxia. Muscle & Nerve. PMID 27061687 DOI: 10.1002/Mus.25136  0.223
2019 Bhatt S, Bodduluri S, Lynch D, Wilson C, Fortis S, Kim V. Computed tomography measures of airway disease are associated with chronic bronchitis European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Oa1915  0.223
2019 Benzaquen S, Chung J, Lynch D, Lederer D, Flaherty K, Colby T, Myers J, Groshong S, Larsen B, Steele M, Calero K, Case A, Criner G, Nathan S, Rai N, et al. COMBINING RADIOLOGY AND ENVISIA, A MOLECULAR CLASSIFIER, TO IMPROVE USUAL INTERSTITIAL PNEUMONIA (UIP) DIAGNOSIS Chest. 156: A253-A256. DOI: 10.1016/J.Chest.2019.08.303  0.222
2017 Regan E, Make B, Kinney G, Budoff M, Dyer D, Curtis J, Bowler R, Han M, Beaty T, Hokanson J, Kern E, Lynch D, Van Beek E, Silverman E, Crapo J, et al. MA05.07 Identifying Comorbid Disease on Chest CT Scans in a Lung Cancer Screening-Eligible Cohort Journal of Thoracic Oncology. 12: S367-S368. DOI: 10.1016/J.Jtho.2016.11.411  0.222
1988 Webb WR, Stein MG, Finkbeiner WE, Im JG, Lynch D, Gamsu G. Normal and diseased isolated lungs: high-resolution CT. Radiology. 166: 81-87. PMID 3336706 DOI: 10.1148/Radiology.166.1.3336706  0.222
2003 Mishizen-Eberz AJ, Guttmann RP, Giasson BI, Day GA, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro. Journal of Neurochemistry. 86: 836-47. PMID 12887682 DOI: 10.1046/J.1471-4159.2003.01878.X  0.222
2012 Singh SP, Gierada DS, Pinsky P, Sanders C, Fineberg N, Sun Y, Lynch D, Nath H. Reader variability in identifying pulmonary nodules on chest radiographs from the national lung screening trial. Journal of Thoracic Imaging. 27: 249-54. PMID 22627615 DOI: 10.1097/Rti.0B013E318256951E  0.221
2021 Dong YN, Hsu FC, Koziol-White CJ, Stepanova V, Jude J, Gritsiuta A, Rue R, Mott R, Coulter DA, Panettieri RA, Krymskaya VP, Takano H, Goncharova EA, Goncharov DA, Cines DB, ... Lynch DR, et al. Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells. Scientific Reports. 11: 8205. PMID 33859248 DOI: 10.1038/s41598-021-87667-0  0.22
2017 Diaz AA, Strand M, Coxson HO, Ross JC, San Jose Estepar R, Lynch D, van Rikxoort EM, Rosas IO, Hunninghake GM, Putman RK, Hatabu H, Yen A, Kinney GL, Hokanson JE, Silverman EK, et al. Disease Severity Dependence Of The Longitudinal Association Between CT Lung Density And Lung Function In Smokers. Chest. PMID 29066389 DOI: 10.1016/J.Chest.2017.10.012  0.219
2010 Paulsen EK, Friedman LS, Myers LM, Lynch DR. Health-related quality of life in children with Friedreich ataxia. Pediatric Neurology. 42: 335-7. PMID 20399387 DOI: 10.1016/J.Pediatrneurol.2010.01.002  0.219
2006 Mazzulli JR, Mishizen AJ, Giasson BI, Lynch DR, Thomas SA, Nakashima A, Nagatsu T, Ota A, Ischiropoulos H. Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10068-78. PMID 17005870 DOI: 10.1523/Jneurosci.0896-06.2006  0.219
1994 Lynch DR, Anegawa NJ, Verdoorn T, Pritchett DB. N-methyl-D-aspartate receptors: different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents. Molecular Pharmacology. 45: 540-5. PMID 7511781  0.218
2000 King J, Costabel U, Cordier JF, DoPico GA, DuBois RM, Lynch D, Lynch JP, Myers J, Panos R, Raghu G, Schwartz D, Smith CM. Idiopathic pulmonary fibrosis: Diagnosis and treatment: International Consensus Statement American Journal of Respiratory and Critical Care Medicine. 161: 646-664. PMID 10673212 DOI: 10.1164/Ajrccm.161.2.Ats3-00  0.218
2018 Hamedani AG, Hauser LA, Perlman S, Mathews K, Wilmot GR, Zesiewicz T, Subramony SH, Ashizawa T, Delatycki MB, Brocht A, Lynch DR. Longitudinal analysis of contrast acuity in Friedreich ataxia. Neurology. Genetics. 4: e250. PMID 30065952 DOI: 10.1212/Nxg.0000000000000250  0.218
2010 Friedman LS, Paulsen EK, Schadt KA, Brigatti KW, Driscoll DA, Farmer JM, Lynch DR. Pregnancy with Friedreich ataxia: a retrospective review of medical risks and psychosocial implications. American Journal of Obstetrics and Gynecology. 203: 224.e1-5. PMID 20478553 DOI: 10.1016/J.Ajog.2010.03.046  0.217
1998 Brimecombe JC, Gallagher MJ, Lynch DR, Aizenman E. An NR2B point mutation affecting haloperidol and CP101,606 sensitivity of single recombinant N-methyl-D-aspartate receptors. The Journal of Pharmacology and Experimental Therapeutics. 286: 627-34. PMID 9694913  0.217
2014 Tenorio SL, O'Donnell CI, Hernandez J, Rozjabek HM, Lynch D, Marcus PM. Culturally sensitive approaches to recruitment and retention of Hispanics in the national lung screening trial. Journal of Immigrant and Minority Health / Center For Minority Public Health. 16: 761-4. PMID 23780349 DOI: 10.1007/S10903-013-9862-0  0.216
2015 Chae KJ, Jin GY, Han YM, Kim YS, Chon SB, Lee YS, Kwon KS, Choi HM, Lynch D. Prevalence and progression of combined pulmonary fibrosis and emphysema in asymptomatic smokers: A case-control study. European Radiology. 25: 2326-34. PMID 25680720 DOI: 10.1007/S00330-015-3617-3  0.216
2013 Fingerlin TE, Murphy E, Zhang W, Peljto AL, Brown KK, Steele MP, Loyd JE, Cosgrove GP, Lynch D, Groshong S, Collard HR, Wolters PJ, Bradford WZ, Kossen K, Seiwert SD, et al. Erratum: Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis Nature Genetics. 45: 1409-1409. DOI: 10.1038/Ng1113-1409A  0.215
2018 LYNCH D, COLBY T, MYERS J, GROSHONG S, STEELE M, PANKRATZ D, CHOI Y, HUANG J, WALSH P, NEVILLE H, LOFARO L, KENNEDY G, BROWN K, RAGHU G. MOLECULAR DIAGNOSIS OF USUAL INTERSTITIAL PNEUMONIA (UIP) FROM TRANSBRONCHIAL BIOPSY IS ACCURATE IN SUBJECTS WITHOUT DEFINITE OR PROBABLE UIP ON CT Chest. 154: 458A-459A. DOI: 10.1016/J.Chest.2018.08.418  0.215
2016 Kesner AL, Chung JH, Lind KE, Kwak JJ, Lynch D, Burckhardt D, Koo PJ. Frequency based gating: An alternative, conformal, approach to 4D PET data utilization. Medical Physics. 43: 1451. PMID 26936729 DOI: 10.1118/1.4941956  0.214
2014 Flaherty KR, Fell C, Aubry MC, Brown K, Colby T, Costabel U, Franks TJ, Gross BH, Hansell DM, Kazerooni E, Kim DS, King TE, Kitachi M, Lynch D, Myers J, et al. Smoking-related idiopathic interstitial pneumonia. The European Respiratory Journal. 44: 594-602. PMID 25063244 DOI: 10.1183/09031936.00166813  0.214
2015 Seyer L, Greeley N, Foerster D, Strawser C, Gelbard S, Dong Y, Schadt K, Cotticelli MG, Brocht A, Farmer J, Wilson RB, Lynch DR. Open-label pilot study of interferon gamma-1b in Friedreich ataxia. Acta Neurologica Scandinavica. 132: 7-15. PMID 25335475 DOI: 10.1111/Ane.12337  0.213
2003 Bearden C, Simon T, Wang P, Lynch D, Jawad A, McDonald-McGinn D, Zackai E, Emanuel B. Effects of a functional COMT polymorphism on neurocognitive function in the 22Q deletion syndrome Schizophrenia Research. 60: 78-79. DOI: 10.1016/S0920-9964(03)80619-9  0.212
2005 Mishizen-Eberz AJ, Norris EH, Giasson BI, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein. Biochemistry. 44: 7818-29. PMID 15909996 DOI: 10.1021/Bi047846Q  0.211
2016 Bui C, Wilson RB, Lynch DR, Rossano JW, Elci O, Lin KY. Cardiac Serum Biomarkers in Friedreich Ataxia May Reflect Fibrosis, Myocyte Injury, and Degree of Hypertrophy Journal of Heart and Lung Transplantation. 35. DOI: 10.1016/J.Healun.2016.01.479  0.211
2018 Lynch DR, Kichula E, Lin H. Frataxin Restoration in the Nervous System: Possibilities for Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 26: 1880-1882. PMID 30078439 DOI: 10.1016/J.Ymthe.2018.06.006  0.21
1992 Lynch D. Imaging of asbestos-related thoracic disease Seminars in Respiratory and Critical Care Medicine. 13: 302-344. DOI: 10.1055/S-2007-1006281  0.21
1998 Lynch D. Imaging techniques in lung disease Seminars in Respiratory and Critical Care Medicine. 19: 407-410. DOI: 10.1055/S-2007-1009418  0.209
2011 Kim YI, Schroeder J, Lynch D, Newell J, Make B, Friedlander A, Estépar RS, Hanania NA, Washko G, Murphy JR, Wilson C, Hokanson JE, Zach J, Butterfield K, Bowler RP, et al. Gender differences of airway dimensions in anatomically matched sites on CT in smokers. Copd. 8: 285-92. PMID 21756032 DOI: 10.3109/15412555.2011.586658  0.209
2008 Sahakian N, Kullman G, Lynch D, Kreiss K. Asthma arising in flavoring-exposed food production workers. International Journal of Occupational Medicine and Environmental Health. 21: 173-177. PMID 18715841 DOI: 10.2478/V10001-008-0019-7  0.209
2019 Oudkerk SF, Mohamed Hoesein FAA, PThM Mali W, Öner FC, Verlaan JJ, de Jong PA, Kinney GL, Hokanson J, Lynch D, Silverman EK, Budoff MJ, Regan EA. Subjects with diffuse idiopathic skeletal hyperostosis have an increased burden of coronary artery disease: An evaluation in the COPDGene cohort. Atherosclerosis. 287: 24-29. PMID 31181416 DOI: 10.1016/J.Atherosclerosis.2019.05.030  0.208
2016 Chen-Mayer H, Judy P, Fain S, Hoppel B, Lynch D, Fuld M. TH-CD-207B-11: Multi-Vendor Phantom Study of CT Lung Density Metrics: Is a Reproducibility of Less Than 1 HU Achievable? Medical Physics. 43: 3891. PMID 28046298 DOI: 10.1118/1.4958217  0.207
2019 Rummey C, Corben LA, Delatycki MB, Subramony SH, Bushara K, Gomez CM, Hoyle JC, Yoon G, Ravina B, Mathews KD, Wilmot G, Zesiewicz T, Perlman S, Farmer JM, Lynch DR. Psychometric properties of the Friedreich Ataxia Rating Scale. Neurology. Genetics. 5: 371. PMID 32042904 DOI: 10.1212/Nxg.0000000000000371  0.207
2013 Jin GY, Lynch D, Chawla A, Garg K, Tammemagi MC, Sahin H, Misumi S, Kwon KS. Interstitial lung abnormalities in a CT lung cancer screening population: prevalence and progression rate. Radiology. 268: 563-71. PMID 23513242 DOI: 10.1148/Radiol.13120816  0.207
2011 Harrington A, Pedraza I, Weisman M, Sachs P, Lynch D, Derber L, Norris J, Holers M, Deane K. Lung Imaging Abnormalities Are Similar in Autoantibody Positive Subjects Without Arthritis and Those With Early Established Rheumatoid Arthritis (RA) Chest. 140: 993A. DOI: 10.1378/Chest.1117118  0.207
2017 Diaz AA, Strand M, Coxson H, Ross J, Jose RS, Lynch D, Rikxoort EV, Kinney G, Hokanson J, Silverman E, Crapo J, Washko G. The variable relationship between changes in lung density and FEV1 in smokers European Respiratory Journal. DOI: 10.1183/1393003.Congress-2017.Pa797  0.205
2016 Lynch DR, Kichula E. Challenges ahead for trials in Friedreich's ataxia. The Lancet. Neurology. 15: 1300-1301. PMID 27839636 DOI: 10.1016/S1474-4422(16)30281-2  0.205
2004 Hodara R, Norris EH, Giasson BI, Mishizen-Eberz AJ, Lynch DR, Lee VM, Ischiropoulos H. Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. The Journal of Biological Chemistry. 279: 47746-53. PMID 15364911 DOI: 10.1074/Jbc.M408906200  0.204
2019 Chung J, Lynch D, Lederer D, Flaherty K, Colby T, Myers J, Groshong S, Larsen B, Steele M, Benzaquen S, Calero K, Case A, Criner G, Nathan S, Rai N, et al. EVALUATING CLINICAL UTILITY OF A UIP GENOMIC CLASSIFIER IN SUBJECTS WITH AND WITHOUT A HRCT PATTERN OF UIP Chest. 156: A175-A178. DOI: 10.1016/J.Chest.2019.08.246  0.204
2014 Greeley NR, Regner S, Willi S, Lynch DR. Cross-sectional analysis of glucose metabolism in Friedreich ataxia. Journal of the Neurological Sciences. 342: 29-35. PMID 24819921 DOI: 10.1016/J.Jns.2014.04.015  0.204
2018 Marchini L, Recker E, Hartshorn J, Cowen H, Lynch D, Drake D, Blanchette DR, Dawson DV, Kanellis M, Caplan D. Iowa nursing facility oral hygiene (INFOH) intervention: A clinical and microbiological pilot randomized trial. Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry For the Handicapped, and the American Society For Geriatric Dentistry. PMID 30194737 DOI: 10.1111/Scd.12327  0.203
2010 Lagedrost S, Plappert T, Sutton MSJ, Lynch D. Influence Of Genetic Factors On Left Ventricular Structure And Function In Friedreich’S Ataxia Journal of the American College of Cardiology. 55. DOI: 10.1016/S0735-1097(10)60260-4  0.203
2011 Lagedrost SJ, Sutton MSJ, Regner SR, Seyer LA, Schadt KA, Cohen MS, Satou GM, Kaufman BD, Perlman SL, Rummey C, Meier T, Lynch DR. Idebenone In Friedreich Ataxia Cardiomyopathy: Results From A 6 Months Phase Iii Study Journal of the American College of Cardiology. 57. DOI: 10.1016/S0735-1097(11)60337-9  0.203
2019 Finigan J, Lowe K, Thiele C, Wilson C, Humphries S, Lynch D, Regan E. P1.11-17 Osteoporosis, Coronary Artery Calcification, and COPD in a Lung Cancer Screening Cohort Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.08.1090  0.201
1998 Bingham PM, Lynch D, McDonald-McGinn D, Zackai E. Polymicrogyria in chromosome 22 delection syndrome. Neurology. 51: 1500-2. PMID 9818897 DOI: 10.1212/Wnl.51.5.1500  0.201
2008 Anheim M, Lagier-Tourenne C, Tazir M, Lopez L, Quinzii C, Drouot N, Assoum M, Makri S, Ali-Pacha L, Lynch D, Mandel J, Hirano M, Tranchant C, Koenig M. ARCA2 : une nouvelle ataxie cérébelleuse autosomique récessive liée à des mutations du gène ADCK3 Revue Neurologique. 164: 31. DOI: 10.1016/S0035-3787(08)70047-X  0.201
2015 Lynch DR, Perlman SL. Friedreich's ataxia: the European consortium. The Lancet. Neurology. 14: 130-1. PMID 25566997 DOI: 10.1016/S1474-4422(14)70327-8  0.197
2019 Nguyen S, Wilson N, Stefanovski D, Gur GM, Dedio A, Wade K, Lynch D, Reddy R, Kelly A, Rickels M, McCormack S. MON-LB030 Muscle Mitochondrial Oxidative Phosphorylation Capacity and Whole Body Glucose Metabolism in Friedreich's Ataxia Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-Lb030  0.197
2019 Arjomandi M, Zeng S, Lynch D, Bowler R. Patterns of development of airflow limitation in smokers with preserved spirometry and air trapping phenotype in COPDGene European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Oa476  0.195
2016 Kesner AL, Chung JH, Lind KE, Kwak JJ, Lynch D, Burckhardt D, Koo PJ. Validation of Software Gating: A Practical Technology for Respiratory Motion Correction in PET. Radiology. 152105. PMID 27027335 DOI: 10.1148/Radiol.2016152105  0.195
2018 Jou SS, Yagihashi K, Zach JA, Lynch D, Suh YJ. Relationship between current smoking, visual CT findings and emphysema index in cigarette smokers. Clinical Imaging. 53: 195-199. PMID 30419414 DOI: 10.1016/J.Clinimag.2018.10.024  0.193
2016 Richards JC, Lynch D, Koelsch T, Dyer D. Imaging of Asthma. Immunology and Allergy Clinics of North America. 36: 529-45. PMID 27401624 DOI: 10.1016/J.Iac.2016.03.005  0.193
2019 Xiong E, Lynch AE, Corben LA, Delatycki MB, Subramony SH, Bushara K, Gomez CM, Hoyle JC, Yoon G, Ravina B, Mathews KD, Wilmot G, Zesiewicz T, Susan Perlman M, Farmer JM, ... ... Lynch DR, et al. Health related quality of life in Friedreich Ataxia in a large heterogeneous cohort. Journal of the Neurological Sciences. 410: 116642. PMID 31901720 DOI: 10.1016/J.Jns.2019.116642  0.191
2019 Stephens MJ, Rho BH, Curran-Everett D, Carr L, Bowler R, Lynch D. Identification of Nonaggressive Pulmonary Nodules Using an Optimized Scoring System. Journal of Thoracic Imaging. PMID 30896542 DOI: 10.1097/Rti.0000000000000405  0.19
2014 Lynch DR, Seyer L. Friedreich ataxia: new findings, new challenges. Annals of Neurology. 76: 487-8. PMID 25159691 DOI: 10.1002/Ana.24259  0.19
2009 Klein JS, Lynch D. In Memoriam: Dr Gordon Gamsu Journal of Thoracic Imaging. 24: 87-88. DOI: 10.1097/Rti.0B013E3181A6D101  0.19
1994 Corn B, Curtis MT, Lynch D, Gomori JM. Malignant oligodendroglioma arising after radiation therapy for lymphoma. Medical and Pediatric Oncology. 22: 45-52. PMID 8232080 DOI: 10.1002/Mpo.2950220109  0.189
2016 Boer Kd, Aravena C, Sood R, Hayden M, Leslie K, Lynch D, Noth I, Flaherty K, Collard H. P065 Virtual multidisciplinary discussion: Feasibility and diagnostic concordance with face-to-face multidisciplinary discussion Qjm: An International Journal of Medicine. 109. DOI: 10.1093/Qjmed/Hcw124.039  0.187
1997 Balcer LJ, Lynch DR, Galetta SL. Neuro-Ophthalmology of the Pregeniculate Afferent Visual System Developments in 1996 (Part I) Journal of Neuro-Ophthalmology. 17: 60???71. DOI: 10.1097/00041327-199703000-00014  0.185
2018 Ejaz R, Chen S, Isaacs CJ, Carnevale A, Wilson J, George K, Delatycki MB, Perlman SL, Mathews KD, Wilmot GR, Hoyle JC, Subramony SH, Zesiewicz T, Farmer JM, Lynch DR, et al. Impact of Mobility Device Use on Quality of Life in Children With Friedreich Ataxia. Journal of Child Neurology. 883073818764941. PMID 29607705 DOI: 10.1177/0883073818764941  0.184
2019 Lynch DR, Schadt K, Kichula E. Etravirine in Friedreich's ataxia: Lessons from HIV? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30629768 DOI: 10.1002/Mds.27605  0.178
2022 Rodden LN, Rummey C, Dong YN, Lynch DR. Clinical Evidence for Variegated Silencing in Patients With Friedreich Ataxia. Neurology. Genetics. 8: e683. PMID 35620135 DOI: 10.1212/NXG.0000000000000683  0.17
2023 Rojsajjakul T, Wu L, Grady CB, Hwang WT, Mesaros C, Lynch DR, Blair IA. Liquid Chromatography-Mass Spectrometry Analysis of Frataxin Proteoforms in Whole Blood as Biomarkers of the Genetic Disease Friedreich's Ataxia. Analytical Chemistry. PMID 36800320 DOI: 10.1021/acs.analchem.3c00091  0.151
2020 Rodríguez-Pascau L, Britti E, Calap-Quintana P, Dong YN, Vergara C, Delaspre F, Medina M, Tamarit J, Pallardó FV, Gonzalez-Cabo P, Ros J, Lynch DR, Martinell M, Pizcueta P. PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia. Neurobiology of Disease. 105162. PMID 33171227 DOI: 10.1016/j.nbd.2020.105162  0.15
2021 Napierala JS, Rajapakshe K, Clark A, Chen YY, Huang S, Mesaros C, Xu P, Blair IA, Hauser LA, Farmer J, Lynch DR, Edwards DP, Coarfa C, Napierala M. Reverse phase protein array reveals correlation of retinoic acid metabolism with cardiomyopathy in Friedreich's ataxia. Molecular & Cellular Proteomics : McP. 100094. PMID 33991687 DOI: 10.1016/j.mcpro.2021.100094  0.15
2022 Mercado-Ayón E, Warren N, Halawani S, Rodden LN, Ngaba L, Dong YN, Chang JC, Fonck C, Mavilio F, Lynch DR, Lin H. Cerebellar Pathology in an Inducible Mouse Model of Friedreich Ataxia. Frontiers in Neuroscience. 16: 819569. PMID 35401081 DOI: 10.3389/fnins.2022.819569  0.15
1989 Lynch DR, Walker MW, Miller RJ, Snyder SH. Neuropeptide Y receptor binding sites in rat brain: Differential autoradiographic localizations with 125I-peptide YY and 125I-neuropeptide Y imply receptor heterogeneity Journal of Neuroscience. 9: 2607-2619. PMID 2549216  0.147
2020 Harding I, Lynch DR, Koeppen A, Pandolfo M. Central Nervous System Therapeutic Targets in Friedreich Ataxia. Human Gene Therapy. PMID 33238751 DOI: 10.1089/hum.2020.264  0.145
2023 Czornobil R, Abou-Assali O, Remily-Wood E, Lynch DR, Noujaim SF, Chidipi B. The Cardiac Calcium Handling Machinery is Remodeled in Friedreich's Ataxia. Biorxiv : the Preprint Server For Biology. PMID 38014032 DOI: 10.1101/2023.11.09.566141  0.138
2021 Lynch DR, Johnson J. Omaveloxolone: potential new agent for Friedreich ataxia. Neurodegenerative Disease Management. PMID 33430645 DOI: 10.2217/nmt-2020-0057  0.133
2016 Kaakoush NO, Thomas DS, Ruzayqat MM, Lynch D, Leach ST, Lemberg DA, Day AS, Mitchell HM. Campylobacter concisus utilizes blood but not short chain fatty acids despite showing associations with Firmicutes taxa. Microbiology (Reading, England). PMID 27339421 DOI: 10.1099/mic.0.000328  0.133
2023 Rodden LN, Rummey C, Kessler S, Wilson RB, Lynch DR. A Novel Metric for Predicting Severity of Disease Features in Friedreich's Ataxia. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 36928898 DOI: 10.1002/mds.29370  0.132
2022 Lynch DR, Mathews KD, Perlman S, Zesiewicz T, Subramony S, Omidvar O, Vogel AP, Krtolica A, Litterman N, van der Ploeg L, Heerinckx F, Milner P, Midei M. Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia. Journal of Neurology. PMID 36462055 DOI: 10.1007/s00415-022-11501-4  0.132
2023 Vizcarra JA, Paul RA, Hamedani AG, Lynch DR, Aamodt WW. Clinical Reasoning: A 48-Year-Old Man With Spasticity and Progressive Ataxia. Neurology. PMID 37596043 DOI: 10.1212/WNL.0000000000207658  0.128
2021 Lynch DR, Schadt K, Kichula E, McCormack S, Lin KY. Friedreich Ataxia: Multidisciplinary Clinical Care. Journal of Multidisciplinary Healthcare. 14: 1645-1658. PMID 34234452 DOI: 10.2147/JMDH.S292945  0.128
2023 Lynch DR, Rojsajjakul T, Subramony SH, Perlman SL, Keita M, Mesaros C, Blair IA. Frataxin analysis using triple quadrupole mass spectrometry: application to a large heterogeneous clinical cohort. Journal of Neurology. PMID 38063871 DOI: 10.1007/s00415-023-12118-x  0.127
2021 Johnson J, Mercado-Ayón E, Clark E, Lynch D, Lin H. Drp1-dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia. Pharmacology Research & Perspectives. 9: e00755. PMID 33951329 DOI: 10.1002/prp2.755  0.125
2022 Keita M, McIntyre K, Rodden LN, Schadt K, Lynch DR. Friedreich ataxia: clinical features and new developments. Neurodegenerative Disease Management. PMID 35766110 DOI: 10.2217/nmt-2022-0011  0.124
2021 Rodden LN, Chutake YK, Gilliam K, Lam C, Soragni E, Hauser L, Gilliam M, Wiley G, Anderson MP, Gottesfeld JM, Lynch DR, Bidichandani SI. Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia. Human Molecular Genetics. PMID 33432325 DOI: 10.1093/hmg/ddaa267  0.123
2022 Rodden LN, Rummey C, Dong YN, Lagedrost S, Regner S, Brocht A, Bushara K, Delatycki MB, Gomez CM, Mathews K, Murray S, Perlman S, Ravina B, Subramony SH, Wilmot G, ... ... Lynch DR, et al. A non-synonymous single nucleotide polymorphism in predicts neurological severity in Friedreich ataxia. Frontiers in Molecular Biosciences. 9: 933788. PMID 36133907 DOI: 10.3389/fmolb.2022.933788  0.122
2021 Rodden LN, Lynch DR. Designing phase II clinical trials in Friedreich ataxia. Expert Opinion On Emerging Drugs. 26: 415-423. PMID 34693848 DOI: 10.1080/14728214.2021.1998452  0.12
2024 Cilenti NA, Tamaroff JG, Capiola CJ, Faig W, McBride MG, Paridon SM, O'Malley S, Edelson JB, Lynch DR, McCormack SE, Lin KY. Cardiopulmonary exercise testing on adaptive equipment in children and adults with Friedreich ataxia. Muscle & Nerve. PMID 38515223 DOI: 10.1002/mus.28085  0.12
2024 Dong YN, Ngaba LV, An J, Adeshina MW, Warren N, Wong J, Lynch DR. A peptide derived from TID1S rescues frataxin deficiency and mitochondrial defects in FRDA cellular models. Frontiers in Pharmacology. 15: 1352311. PMID 38495102 DOI: 10.3389/fphar.2024.1352311  0.12
2024 Shen MM, Rummey C, Lynch DR. Phenotypic variation of FXN compound heterozygotes in a Friedreich ataxia cohort. Annals of Clinical and Translational Neurology. PMID 38396238 DOI: 10.1002/acn3.52027  0.12
2022 Wang Q, Laboureur L, Weng L, Eskenazi NM, Hauser LA, Mesaros C, Lynch DR, Blair IA. Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood. Frontiers in Neuroscience. 16: 874768. PMID 35573317 DOI: 10.3389/fnins.2022.874768  0.12
2024 Lynch DR, Subramony S, Lin KY, Mathews K, Perlman S, Yoon G, Rummey C. Characterization of Cardiac-Onset Initial Presentation in Friedreich Ataxia. Pediatric Cardiology. PMID 38427090 DOI: 10.1007/s00246-024-03429-5  0.119
2022 Wang D, Ho ES, Cotticelli MG, Xu P, Napierala JS, Hauser LA, Napierala M, Himes BE, Wilson RB, Lynch DR, Mesaros C. Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia. Journal of Lipid Research. 100255. PMID 35850241 DOI: 10.1016/j.jlr.2022.100255  0.118
2017 Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros CA, Lynch DR, Blair IA. Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia. Analytical Chemistry. PMID 29272104 DOI: 10.1021/acs.analchem.7b04590  0.117
2021 Lynch DR, Farmer G. Mitochondrial and metabolic dysfunction in Friedreich ataxia: update on pathophysiological relevance and clinical interventions. Neuronal Signaling. 5: NS20200093. PMID 34046211 DOI: 10.1042/NS20200093  0.115
2015 Koutsis G, Lynch D, Manole A, Karadima G, Reilly MM, Houlden H, Panas M. Erratum to: Charcot-Marie-Tooth disease type 2C and scapuloperoneal muscular atrophy overlap syndrome in a patient with the R232C TRPV4 mutation. Journal of Neurology. 262: 1976. PMID 26162716 DOI: 10.1007/s00415-015-7846-9  0.115
2015 Koutsis G, Lynch D, Manone A, Karadima G, Reilly MM, Houlden H, Panas M. Charcot-Marie-Tooth disease type 2C and scapuloperoneal muscular atrophy overlap syndrome in a patient with the R232C TRPV4 mutation. Journal of Neurology. 262: 1972-5. PMID 26048687 DOI: 10.1007/s00415-015-7800-x  0.114
2022 Lynch DR, Chin MP, Boesch S, Delatycki MB, Giunti P, Goldsberry A, Hoyle JC, Mariotti C, Mathews KD, Nachbauer W, O'Grady M, Perlman S, Subramony SH, Wilmot G, Zesiewicz T, et al. Efficacy of Omaveloxolone in Friedreich's Ataxia: Delayed-Start Analysis of the MOXIe Extension. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 36444905 DOI: 10.1002/mds.29286  0.114
2023 Seabury J, Rosero S, Varma A, Weinstein J, Engebrecht C, Dilek N, Heatwole J, Alexandrou D, Cohen B, Larkindale J, Lynch DR, Park C, Subramony SH, Wagner E, Walther S, et al. Friedreich's Ataxia-Health Index: Development and Validation of a Novel Disease-Specific Patient-Reported Outcome Measure. Neurology. Clinical Practice. 13: e200180. PMID 37646046 DOI: 10.1212/CPJ.0000000000200180  0.114
2022 Georgiou-Karistianis N, Corben LA, Reetz K, Adanyeguh IM, Corti M, Deelchand DK, Delatycki MB, Dogan I, Evans R, Farmer J, França MC, Gaetz W, Harding IH, Harris KS, Hersch S, ... ... Lynch D, et al. A natural history study to track brain and spinal cord changes in individuals with Friedreich's ataxia: TRACK-FA study protocol. Plos One. 17: e0269649. PMID 36410013 DOI: 10.1371/journal.pone.0269649  0.113
2018 Clark E, Johnson J, Dong YN, Mercado-Ayon E, Warren N, Zhai M, McMillan E, Salovin A, Lin H, Lynch DR. Role of frataxin protein deficiency and metabolic dysfunction in Friedreich ataxia, an autosomal recessive mitochondrial disease. Neuronal Signaling. 2: NS20180060. PMID 32714592 DOI: 10.1042/NS20180060  0.113
2020 Weng L, Laboureur L, Wang Q, Guo L, Xu P, Gottlieb L, Lynch DR, Mesaros C, Blair IA. Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich's ataxia. Scientific Reports. 10: 15788. PMID 32978498 DOI: 10.1038/s41598-020-72884-w  0.112
2024 Chang JC, Ryan MR, Stark MC, Liu S, Purushothaman P, Bolan F, Johnson CA, Champe M, Meng H, Lawlor MW, Halawani S, Ngaba LV, Lynch DR, Davis C, Gonzalo-Gil E, et al. AAV8 gene therapy reverses cardiac pathology and prevents early mortality in a mouse model of Friedreich's ataxia. Molecular Therapy. Methods & Clinical Development. 32: 101193. PMID 38352270 DOI: 10.1016/j.omtm.2024.101193  0.112
2021 Rodden LN, Gilliam KM, Lam C, Lynch DR, Bidichandani SI. Epigenetic Heterogeneity in Friedreich Ataxia Underlies Variable Reactivation. Frontiers in Neuroscience. 15: 752921. PMID 34899161 DOI: 10.3389/fnins.2021.752921  0.112
2022 Thomas-Black G, Dumitrascu A, Garcia-Moreno H, Vallortigara J, Greenfield J, Hunt B, Walther S, Wells M, Lynch DR, Montgomery H, Giunti P. The attitude of patients with progressive ataxias towards clinical trials. Orphanet Journal of Rare Diseases. 17: 1. PMID 34983593 DOI: 10.1186/s13023-021-02091-x  0.111
2012 Lynch DR, Khan FH, Vaidya D, Williams MS. Persistent high on-treatment platelet reactivity in acute coronary syndrome. Journal of Thrombosis and Thrombolysis. 33: 267-73. PMID 22362558 DOI: 10.1007/s11239-012-0678-x  0.109
2023 Profeta V, McIntyre K, Wells M, Park C, Lynch DR. Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia. Expert Opinion On Investigational Drugs. 32: 5-16. PMID 36708320 DOI: 10.1080/13543784.2023.2173063  0.108
2022 Shen MM, Rodden LN, McIntyre K, Arias A, Profeta V, Schadt K, Lynch DR. SARS-CoV-2 in patients with Friedreich ataxia. Journal of Neurology. PMID 36219242 DOI: 10.1007/s00415-022-11419-x  0.108
2014 Corben LA, Lynch D, Pandolfo M, Schulz JB, Delatycki MB. Consensus clinical management guidelines for Friedreich ataxia. Orphanet Journal of Rare Diseases. 9: 184. PMID 25928624 DOI: 10.1186/s13023-014-0184-7  0.106
2021 Li Y, Li J, Wang J, Lynch DR, Shen X, R Corey D, Parekh D, Bhat B, Woo C, Cherry JJ, Napierala JS, Napierala M. Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression. Nucleic Acids Research. PMID 34718736 DOI: 10.1093/nar/gkab954  0.105
2022 Strand M, Khatiwada A, Baraghoshi D, Lynch D, Silverman EK, Bhatt SP, Austin E, Regan EA, Boriek AM, Crapo JD. Predicting COPD Progression in Current and Former Smokers Using a Joint Model for Forced Expiratory Volume in 1 Second and Forced Expiratory Volume in 1 Second to Forced Vital Capacity Ratio. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 9: 439-453. PMID 35905755 DOI: 10.15326/jcopdf.2022.0281  0.103
2022 Dong YN, Mesaros C, Xu P, Mercado-Ayón E, Halawani S, Ngaba LV, Warren N, Sleiman P, Rodden LN, Schadt KA, Blair IA, Lynch DR. Frataxin controls ketone body metabolism through regulation of OXCT1. Pnas Nexus. 1: pgac142. PMID 36016708 DOI: 10.1093/pnasnexus/pgac142  0.103
2020 Johnson J, Mercado-Ayón E, Mercado-Ayón Y, Dong YN, Halawani S, Ngaba L, Lynch DR. Mitochondrial dysfunction in the development and progression of neurodegenerative diseases. Archives of Biochemistry and Biophysics. 108698. PMID 33259796 DOI: 10.1016/j.abb.2020.108698  0.102
2023 Lynch DR, Goldsberry A, Rummey C, Farmer J, Boesch S, Delatycki MB, Giunti P, Hoyle JC, Mariotti C, Mathews KD, Nachbauer W, Perlman S, Subramony SH, Wilmot G, Zesiewicz T, et al. Propensity matched comparison of omaveloxolone treatment to Friedreich ataxia natural history data. Annals of Clinical and Translational Neurology. PMID 37691319 DOI: 10.1002/acn3.51897  0.101
2021 Runge E, Kou CJ, Rendo M, Lynch D, Fenderson J. Lenalidomide-Associated Hemophagocytic Lymphohistiocytosis With Plasma Cell Phagocytosis. Cureus. 13: e14409. PMID 33987058 DOI: 10.7759/cureus.14409  0.1
2016 Lynch D, Murphy A. The emerging role of immunotherapy in colorectal cancer. Annals of Translational Medicine. 4: 305. PMID 27668225 DOI: 10.21037/atm.2016.08.29  0.1
2023 Lam C, Gilliam KM, Rodden LN, Schadt KA, Lynch DR, Bidichandani S. gene methylation determines carrier status in Friedreich ataxia. Journal of Medical Genetics. PMID 36635061 DOI: 10.1136/jmg-2022-108742  0.099
2020 Lynch DR, Chin MP, Delatycki MB, Subramony SH, Corti M, Hoyle JC, Boesch S, Nachbauer W, Mariotti C, Mathews KD, Giunti P, Wilmot G, Zesiewicz T, Perlman S, Goldsberry A, et al. Safety and Efficacy of Omaveloxolone in Friedreich's Ataxia (MOXIe Study). Annals of Neurology. PMID 33068037 DOI: 10.1002/ana.25934  0.098
2020 Sareen H, Garrett C, Lynch D, Powter B, Brungs D, Cooper A, Po J, Koh ES, Vessey JY, McKechnie S, Bazina R, Sheridan M, Gelder JV, Darwish B, Jaeger M, et al. The Role of Liquid Biopsies in Detecting Molecular Tumor Biomarkers in Brain Cancer Patients. Cancers. 12. PMID 32650387 DOI: 10.3390/cancers12071831  0.097
2022 Rodden LN, Gilliam KM, Lam C, Rojsajjakul T, Mesaros C, Dionisi C, Pook M, Pandolfo M, Lynch DR, Blair IA, Bidichandani SI. DNA methylation in Friedreich ataxia silences expression of frataxin isoform E. Scientific Reports. 12: 5031. PMID 35322126 DOI: 10.1038/s41598-022-09002-5  0.097
2021 Mueller A, Paterson E, McIntosh A, Praestgaard J, Bylo M, Hoefling H, Wells M, Lynch DR, Rummey C, Krishnan ML, Schultz M, Malanga CJ. Digital endpoints for self-administered home-based functional assessment in pediatric Friedreich's ataxia. Annals of Clinical and Translational Neurology. PMID 34355532 DOI: 10.1002/acn3.51438  0.097
2022 Seabury J, Alexandrou D, Dilek N, Cohen B, Heatwole J, Larkindale J, Lynch DR, Park C, Rosero S, Subramony SH, Varma A, Wagner E, Walther S, Weinstein J, Wells M, et al. Patient-Reported Impact of Symptoms in Friedreich Ataxia. Neurology. PMID 36443012 DOI: 10.1212/WNL.0000000000201598  0.097
2022 Rummey C, Corben LA, Delatycki M, Wilmot G, Subramony SH, Corti M, Bushara K, Duquette A, Gomez C, Hoyle JC, Roxburgh R, Seeberger L, Yoon G, Mathews K, Zesiewicz T, ... ... Lynch DR, et al. Natural History of Friedreich's Ataxia: Heterogeneity of Neurological Progression and Consequences for Clinical Trial Design. Neurology. PMID 35817567 DOI: 10.1212/WNL.0000000000200913  0.097
2022 Corben LA, Collins V, Milne S, Farmer J, Musheno A, Lynch D, Subramony S, Pandolfo M, Schulz JB, Lin K, Delatycki MB. Clinical management guidelines for Friedreich ataxia: best practice in rare diseases. Orphanet Journal of Rare Diseases. 17: 415. PMID 36371255 DOI: 10.1186/s13023-022-02568-3  0.096
2021 Yang SR, Beasley MB, Churg A, Colby TV, Fernández Pérez ER, Lynch D, Müller NL, Travis WD. Diagnosis of Hypersensitivity Pneumonitis: Review and Summary of American College of Chest Physicians Statement. The American Journal of Surgical Pathology. PMID 34753865 DOI: 10.1097/PAS.0000000000001827  0.094
2023 Raoof S, Shah M, Make B, Allaqaband H, Bowler R, Fernando S, Greenberg H, Han M, Hogg J, Humphries S, Lee KS, Lynch D, Machnicki S, Mehta A, Mina B, et al. Lung Imaging in COPD: Part 1: Clinical Utility. Chest. PMID 36907372 DOI: 10.1016/j.chest.2023.03.007  0.094
2019 Ding PN, Becker T, Bray V, Chua W, Ma Y, Xu B, Lynch D, de Souza P, Roberts T. Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib. Thoracic Cancer. PMID 31414729 DOI: 10.1111/1759-7714.13154  0.092
2021 Po JW, Ma Y, Luk AWS, Lynch D, Balakrishnar B, Brungs D, Azimi F, Cooper A, Saricilar E, Murthy V, de Souza P, Becker TM. Single-Cell Analysis of BRAF and NRAS Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells. Methods in Molecular Biology (Clifton, N.J.). 2265: 277-286. PMID 33704722 DOI: 10.1007/978-1-0716-1205-7_21  0.092
2019 Li P, Shahmarvand N, Lynch D, Gotlib JR, Merker JD, Zehnder JL, George TI, Ohgami RS. Revisiting diagnostic criteria for myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis: Borderline cases without anemia exist. International Journal of Laboratory Hematology. PMID 30811101 DOI: 10.1111/Ijlh.12981  0.091
2016 Andrade J, Schwarz M, Collard HR, Gentry-Bumpass T, Colby T, Lynch D, Kaner RJ. The Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet): diagnostic and adjudication processes. Chest. 148: 1034-1042. PMID 26111071 DOI: 10.1378/chest.14-2889  0.091
2006 Quaife RA, Chen MY, Lynch D, Badesch DB, Groves BM, Wolfel E, Robertson AD, Bristow MR, Voelkel NF. Importance of right ventricular end-systolic regional wall stress in idiopathic pulmonary arterial hypertension: a new method for estimation of right ventricular wall stress. European Journal of Medical Research. 11: 214-20. PMID 16723296  0.09
2023 Rodden LN, McIntyre K, Keita M, Wells M, Park C, Profeta V, Waldman A, Rummey C, Balcer LJ, Lynch DR. Retinal hypoplasia and degeneration result in vision loss in Friedreich ataxia. Annals of Clinical and Translational Neurology. PMID 37334854 DOI: 10.1002/acn3.51830  0.09
2003 Lum JJ, Cohen OJ, Nie Z, Weaver JG, Gomez TS, Yao XJ, Lynch D, Pilon AA, Hawley N, Kim JE, Chen Z, Montpetit M, Sanchez-Dardon J, Cohen EA, Badley AD. Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. The Journal of Clinical Investigation. 111: 1547-54. PMID 12750404 DOI: 10.1172/Jci16233  0.088
2016 Ma Y, Luk A, Young FP, Lynch D, Chua W, Balakrishnar B, de Souza P, Becker TM. Droplet Digital PCR Based Androgen Receptor Variant 7 (AR-V7) Detection from Prostate Cancer Patient Blood Biopsies. International Journal of Molecular Sciences. 17. PMID 27527157 DOI: 10.3390/ijms17081264  0.088
2021 Wang H, Norton J, Xu L, DeMartinis N, Sen R, Shah A, Farmer J, Lynch D. Results of a randomized double-blind study evaluating luvadaxistat in adults with Friedreich ataxia. Annals of Clinical and Translational Neurology. PMID 34018342 DOI: 10.1002/acn3.51373  0.088
2024 Lynch DR, Perlman S, Schadt K. Omaveloxolone for the treatment of Friedreich ataxia: clinical trial results and practical considerations. Expert Review of Neurotherapeutics. 1-8. PMID 38269532 DOI: 10.1080/14737175.2024.2310617  0.087
2018 Po JW, Roohullah A, Lynch D, DeFazio A, Harrison M, Harnett PR, Kennedy C, de Souza P, Becker TM. Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin. Journal of Circulating Biomarkers. 7: 1849454418782617. PMID 30013673 DOI: 10.1177/1849454418782617  0.084
2019 Lynch D, O'Connor PM, Cotter PD, Hill C, Field D, Begley M. Identification and characterisation of capidermicin, a novel bacteriocin produced by Staphylococcus capitis. Plos One. 14: e0223541. PMID 31618225 DOI: 10.1371/journal.pone.0223541  0.082
2021 Schur GM, Dunn J, Nguyen S, Dedio A, Wade K, Tamaroff J, Mitta N, Wilson N, Reddy R, Lynch DR, McCormack SE. In vivo assessment of OXPHOS capacity using 3 T CrCEST MRI in Friedreich's ataxia. Journal of Neurology. PMID 34652504 DOI: 10.1007/s00415-021-10821-1  0.077
2021 Rummey C, Flynn JM, Corben LA, Delatycki MB, Wilmot G, Subramony SH, Bushara K, Duquette A, Gomez CM, Hoyle JC, Roxburgh R, Seeberger L, Yoon G, Mathews KD, Zesiewicz T, ... ... Lynch DR, et al. Scoliosis in Friedreich's ataxia: longitudinal characterization in a large heterogeneous cohort. Annals of Clinical and Translational Neurology. PMID 33949801 DOI: 10.1002/acn3.51352  0.077
2023 Chae KJ, Lim S, Seo JB, Hwang HJ, Choi H, Lynch D, Jin GY. Interstitial Lung Abnormalities at CT in the Korean National Lung Cancer Screening Program: Prevalence and Deep Learning-based Texture Analysis. Radiology. 222828. PMID 37097142 DOI: 10.1148/radiol.222828  0.074
2023 Raoof S, Shah M, Braman S, Agrawal A, Allaqaband H, Bowler R, Castaldi P, DeMeo D, Fernando S, Hall CS, Han M, Hogg J, Humphries S, Lee HY, Lee KS, ... Lynch D, et al. Lung Imaging of COPD: Part 2: Emerging Concepts Lung Imaging in COPD: Part 2: Emerging Concepts. Chest. PMID 36907375 DOI: 10.1016/j.chest.2023.02.049  0.074
2021 Mejia E, Lynch A, Hearle P, Okunowo O, Griffis H, Shah M, Lynch D, Lin KY. Ectopic Burden via Holter Monitors in Friedreich Ataxia. Pediatric Neurology. 117: 29-33. PMID 33652339 DOI: 10.1016/j.pediatrneurol.2021.01.004  0.073
2005 McGillicuddy DJ, Anderson DM, Lynch DR, Townsend DW. Mechanisms regulating large-scale seasonal fluctuations in Alexandrium fundyense populations in the Gulf of Maine: Results from a physical-biological model Deep-Sea Research Part Ii: Topical Studies in Oceanography. 52: 2698-2714. DOI: 10.1016/J.Dsr2.2005.06.021  0.072
2018 Ding PN, Ma YF, Roberts TJ, Chua W, Bray VJ, Lynch D, Burke D, Souza Pd, Becker TM. Droplet Digital PCR Based Detection of EGFR Mutations in Advanced Lung Cancer Patient Liquid Biopsies: A Comparison of Circulating Tumour DNA Extraction Kits Journal of Molecular Biomarkers & Diagnosis. 9. DOI: 10.4172/2155-9929.1000397  0.072
2021 Garrett C, Becker TM, Lynch D, Po J, Xuan W, Scott KF, de Souza P. Comparison of neutrophil to lymphocyte ratio and prognostic nutritional index with other clinical and molecular biomarkers for prediction of glioblastoma multiforme outcome. Plos One. 16: e0252614. PMID 34138894 DOI: 10.1371/journal.pone.0252614  0.07
1990 Yuan X, Strohbehn JW, Lynch DR, Johnsen M. Theoretical investigation of a phased-array hyperthermia system with movable apertures International Journal of Hyperthermia. 6: 227-240. PMID 2299235 DOI: 10.3109/02656739009140818  0.069
1989 Strohbehn JW, Curtis EH, Paulsen KD, Yuan XC, Lynch DR. Optimization of the absorbed power distribution for an annular phased array hyperthermia system. International Journal of Radiation Oncology, Biology, Physics. 16: 589-99. PMID 2921161 DOI: 10.1016/0360-3016(89)90474-4  0.069
2021 Patel M, McCormick A, Tamaroff J, Dunn J, Mitchell JA, Lin KY, Farmer J, Rummey C, Perlman SL, Delatycki MB, Wilmot GR, Mathews KD, Yoon G, Hoyle J, Corti M, ... ... Lynch D, et al. Body Mass Index and Height in the Friedreich Ataxia Clinical Outcome Measures Study. Neurology. Genetics. 7: e638. PMID 34786480 DOI: 10.1212/NXG.0000000000000638  0.069
2022 Vásquez-Trincado C, Dunn J, Han JI, Hymms B, Tamaroff J, Patel M, Nguyen S, Dedio A, Wade K, Enigwe C, Nichtova Z, Lynch DR, Csordas G, McCormack SE, Seifert EL. Frataxin deficiency lowers lean mass and triggers the integrated stress response in skeletal muscle. Jci Insight. 7. PMID 35531957 DOI: 10.1172/jci.insight.155201  0.068
1997 Kawchuk LM, Lynch DR, Martin RR, Kozub GC, Farries B. Field resistance to the potato leafroll luteovirus in transgenic and somaclone potato plants reduces tuber disease symptoms Canadian Journal of Plant Pathology. 19: 260-266.  0.068
1984 Paulsen KD, Strohbehn JW, Lynch DR. Theoretical temperature distributions produced by an annular phased array-type system in CT-based patient models Radiation Research. 100: 536-552. PMID 6505143 DOI: 10.2307/3576417  0.066
1997 Lynch DR, Holboke MJ, Naimie CE. The Maine coastal current: Spring climatological circulation Continental Shelf Research. 17: 605-634. DOI: 10.1016/S0278-4343(96)00055-6  0.063
2003 McLaughlin JW, Bilgili A, Lynch DR. Numerical modeling of tides in the Great Bay Estuarine System: Dynamical balance and spring-neap residual modulation Estuarine, Coastal and Shelf Science. 57: 283-296. DOI: 10.1016/S0272-7714(02)00355-4  0.063
2016 Hu S, Bansal P, Lynch D, Rojas Hernandez CM, Dayao Z. Rituximab, etoposide, methylprednisolone, high-dose cytarabine, and cisplatin in the treatment of secondary hemophagocytic lymphohistiocytosis with classical Hodgkin lymphoma: a case report and review of the literature. Journal of Medical Case Reports. 10: 365. PMID 27998299 DOI: 10.1186/s13256-016-1143-9  0.062
1985 Paulsen KD, Strohbehn JW, Lynch DR. THEORETICAL ANALYSIS OF THE BENEFITS OF AMPLITUDE AND PHASE CONTROL FOR AN ANNULAR PHASED ARRAY HYPERTHERMIA SYSTEM FOR CANCER THERAPY Bioengineering, Proceedings of the Northeast Conference. 74-77.  0.061
2010 Lynch DR, Smith KW. Lagrangian dispersion in sheared flow Continental Shelf Research. 30: 2092-2105. DOI: 10.1016/J.Csr.2010.10.011  0.06
2001 Lynch DR, Kozub GC, Kawchuk LM. The relationship between yield, mainstem number, and tuber number in five maincrop and two early-maturing cultivars American Journal of Potato Research. 78: 83-90.  0.059
2018 Brungs D, Lynch D, Luk AW, Minaei E, Ranson M, Aghmesheh M, Vine KL, Carolan M, Jaber M, de Souza P, Becker TM. Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer. World Journal of Gastroenterology. 24: 810-818. PMID 29467551 DOI: 10.3748/wjg.v24.i7.810  0.056
2004 Lynch DR, Chen Q, Kawchuk LM, Driedger D. Verticillium wilt resistant germplasm-release of clone LRC18-21 and derivatives American Journal of Potato Research. 81: 295-297.  0.056
2012 Freeman AM, Fenster BE, Weinberger HD, Buckner JK, Lynch D. Hypoxia caused by persistent left superior vena cava connecting to the left atrium a rare clinical entity. Texas Heart Institute Journal / From the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 39: 662-4. PMID 23109762  0.055
1985 Paulsen KD, Strohbehn JW, Lynch DR. Comparative theoretical performance for two types of regional hyperthermia systems International Journal of Radiation Oncology, Biology, Physics. 11: 1659-1671. PMID 4030434 DOI: 10.1016/0360-3016(85)90219-6  0.055
1983 Kaldy MS, Lynch DR. Chlorogenic acid content of Russet Burbank potato in Alberta American Potato Journal. 60: 375-377. DOI: 10.1007/BF02854085  0.054
2022 Tamaroff J, DeDio A, Wade K, Wells M, Park C, Leavens K, Rummey C, Kelly A, Lynch DR, McCormack SE. Friedreich's Ataxia related Diabetes: Epidemiology and management practices. Diabetes Research and Clinical Practice. 186: 109828. PMID 35301072 DOI: 10.1016/j.diabres.2022.109828  0.054
1987 Schaalje GB, Lynch DR, Kozub GC. Field evaluation of a modified augmented design for early stage selection involving a large number of test lines without replication Potato Research. 30: 35-45. DOI: 10.1007/BF02357682  0.053
2009 Bothwell ML, Lynch DR, Wright H, Deniseger J. Introduced species: Invasive species policy at the regional level: A multiple weak links problem Fisheries. 34: 382-388.  0.053
2008 Yalavarthy PK, Lynch DR, Pogue BW, Dehghani H, Paulsen KD. Implementation of a computationally efficient least-squares algorithm for highly under-determined three-dimensional diffuse optical tomography problems. Medical Physics. 35: 1682-97. PMID 18561643 DOI: 10.1118/1.2889778  0.053
2021 Frempong B, Wilson RB, Schadt K, Lynch DR. The Role of Serum Levels of Neurofilament Light (NfL) Chain as a Biomarker in Friedreich Ataxia. Frontiers in Neuroscience. 15: 653241. PMID 33737864 DOI: 10.3389/fnins.2021.653241  0.052
2022 Dunn J, Tamaroff J, DeDio A, Nguyen S, Wade K, Cilenti N, Weber DR, Lynch DR, McCormack SE. Bone Mineral Density and Current Bone Health Screening Practices in Friedreich's Ataxia. Frontiers in Neuroscience. 16: 818750. PMID 35368287 DOI: 10.3389/fnins.2022.818750  0.052
1987 Sullivan JM, Lynch DR, O'Neill K. Finite element simulation of planar instabilities during solidification of an undercooled melt Journal of Computational Physics. 69: 81-111. DOI: 10.1016/0021-9991(87)90157-4  0.052
2004 Lynch DR, Smith KW, Cahill B. Seasonal mean circulation on the Irish shelf - A model-generated climatology Continental Shelf Research. 24: 2215-2244. DOI: 10.1016/J.Csr.2004.07.022  0.052
1987 Lynch DR, Schaalje GB, Tai GCC, Young DA. Use of canonical discriminant analysis in assessing the merit of crosses in terms of breeding goals American Potato Journal. 64: 385-395. DOI: 10.1007/BF02853700  0.051
2003 Bilgili A, Swift MR, Lynch DR, Ip JTC. Modeling bed-load transport of coarse sediments in the Great Bay Estuary, New Hampshire Estuarine, Coastal and Shelf Science. 58: 937-950. DOI: 10.1016/J.Ecss.2003.07.007  0.051
1983 Lynch DR, Tai GCC, Young DA, Schaalje GB. Effect of selecting potato seedlings under maritime conditions on the performance of the first clonal generation under Prairie conditions American Potato Journal. 60: 607-615. DOI: 10.1007/BF02854110  0.05
2006 Hai YL, Chen Q, Beasley D, Lynch DR, Goettel M. Karyotypic evolution and molecular cytogenetic analysis of Solanum pinnatisectum, a new source of resistance to late blight and Colorado potato beetle in potato Cytologia. 71: 25-33. DOI: 10.1508/cytologia.71.25  0.05
2017 Reeves A, Lynch D. Transparency in stereopsis: parallel encoding of overlapping depth planes. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 34: 1424-1432. PMID 29036109 DOI: 10.1364/Josaa.34.001424  0.049
1996 Lynch DR, Ip JTC, Naimie CE, Werner FE. Comprehensive coastal circulation model with application to the Gulf of Maine Continental Shelf Research. 16: 875-906.  0.049
1997 Lynch DR, Naimie CE. Hydrographic data assimilation on Georges Bank Proceedings of the International Conference On Estuarine and Coastal Modeling. 523-540.  0.049
1992 Nelson GA, Lynch DR, Kozub GC. Ring rot symptom development on potato cultivars and lines in southern Alberta Potato Research. 35: 133-142. DOI: 10.1007/BF02357606  0.049
2015 Lynch DR, Fearon WF. Landmark Fractional Flow Reserve Trials Interventional Cardiology Clinics. 4: 435-441. DOI: 10.1016/j.iccl.2015.06.004  0.048
2017 Fenton M, Lynch D, Kucera S, Claussen H, O'Neill M. Multilayer Optimization of Heterogeneous Networks Using Grammatical Genetic Programming. Ieee Transactions On Cybernetics. PMID 28410114 DOI: 10.1109/TCYB.2017.2688280  0.048
1992 Lynch DR, Werner FE, Greenberg DA, Loder JW. Diagnostic model for baroclinic, wind-driven and tidal circulation in shallow seas Continental Shelf Research. 12: 37-64. DOI: 10.1016/0278-4343(92)90005-5  0.048
1998 Lynch DR, Naimie CE, Hannah CG. Hindcasting the Georges Bank circulation. Part I: Detiding Continental Shelf Research. 18: 607-639. DOI: 10.1016/S0278-4343(98)00007-7  0.047
2006 Bilgili A, Smith KW, Lynch DR. BatTri: A two-dimensional bathymetry-based unstructured triangular grid generator for finite element circulation modeling Computers and Geosciences. 32: 632-642. DOI: 10.1016/J.Cageo.2005.09.007  0.046
1998 Kawchuk LM, Hachey J, Lynch DR. Development of sequence characterized dna markers linked to a dominant verticillium wilt resistance gene in tomato Genome. 41: 91-95. PMID 9549062  0.046
1988 Officer CB, Newman WS, Sullivan JM, Lynch DR. Glacial isostatic adjustment and mantle viscosity Journal of Geophysical Research. 93: 6397-6409.  0.046
2005 Proehl JA, Lynch DR, McGillicuddy DJ, Ledwell JR. Modeling turbulent dispersion on the North Flank of Georges Bank using Lagrangian Particle Methods Continental Shelf Research. 25: 875-900. DOI: 10.1016/J.Csr.2004.09.022  0.045
1993 Lynch DR, Naimie CE. The M2 tide and its residual on the outer banks of the Gulf of Maine Journal of Physical Oceanography. 23: 2222-2253.  0.045
2021 Lynch D, Hill C, Field D, Begley M. Inhibition of Listeria monocytogenes by the Staphylococcus capitis - derived bacteriocin capidermicin. Food Microbiology. 94: 103661. PMID 33279086 DOI: 10.1016/j.fm.2020.103661  0.044
1982 Straub WA, Lynch DR. Models of landfill leaching: organic strength Journal of the Environmental Engineering Division - Asce. 108: 251-268.  0.043
2018 Fenton M, Lynch D, Fagan D, Kucera S, Claussen H, O'Neill M. Towards Automation & Augmentation of the Design of Schedulers for Cellular Communications Networks. Evolutionary Computation. 1-30. PMID 29528725 DOI: 10.1162/evco_a_00221  0.043
1983 Officer CB, Lynch DR. Determination of mixing parameters from tracer distributions in deep-sea sediment cores Marine Geology. 52: 59-74. DOI: 10.1016/0025-3227(83)90021-X  0.042
1988 Lynch DR, Coffin RH. Effect of short- and long-term exposure of seed tubers to low temperatures on the growth and yield of five potato cultivars American Potato Journal. 65: 57-66. DOI: 10.1007/BF02867453  0.042
1996 Demeke T, Lynch DR, Kawchuk LM, Kozub GC, Armstrong JD. Genetic diversity of potato determined by random amplified polymorphic DNA analysis Plant Cell Reports. 15: 662-667. DOI: 10.1007/BF00231920  0.042
1997 Lynch DR, Holboke MJ. Normal flow boundary conditions in 3D circulation models International Journal For Numerical Methods in Fluids. 25: 1185-1205.  0.041
1998 Greenberg DA, Werner FE, Lynch DR. A diagnostic finite-element ocean circulation model in spherical-polar coordinates Journal of Atmospheric and Oceanic Technology. 15: 942-958.  0.041
1977 Lynch DR, Rowberry RG. Population density studies with Russet Burbank II. The effect of fertilization and plant density on growth, development and yield American Potato Journal. 54: 57-71. DOI: 10.1007/BF02851874  0.041
1992 Lynch DR, Coffin RH. Short-Term exposure to low temperature in the fall affects field performance of seed tubers American Potato Journal. 69: 143-148. DOI: 10.1007/BF02855343  0.041
2012 Barnes A, Lynch DR. From the classroom to the museum: Understanding faculty-designed assignments in an academic museum Museum Management and Curatorship. 27: 487-503. DOI: 10.1080/09647775.2012.738134  0.041
1993 Demeke T, Kawchuk LM, Lynch DR. Identification of potato cultivars and clonal variants by random amplified polymorphic DNA analysis American Potato Journal. 70: 561-570. DOI: 10.1007/BF02850846  0.04
1984 Mains WH, Lynch DR. Modification of a Hassia Potato Harvester to reduce tuber damage American Potato Journal. 61: 107-108. DOI: 10.1007/BF02852884  0.04
1980 Lynch DR. Moving boundary numerical surge model. (Discussion of Paper 14758) J. Waterway Port Coastal &Amp; Ocean Div.: Proc. Asce.. 106: 425-428.  0.04
2000 Kozub JG, Lynch DR, Kozub GC, Kawchuk LM, Fujimoto DK. A relational database system for potato breeding programs American Journal of Potato Research. 77: 95-101.  0.04
1990 Lynch DR, Werner FE, Molines JM, Fornerino M. Tidal dynamics in a coupled ocean/lake system Estuarine, Coastal and Shelf Science. 31: 319-343. DOI: 10.1016/0272-7714(90)90107-3  0.04
1984 Lynch DR, Hazard JL. Dynamic velocity profiles on simple elements - model design and testing 0.039
1994 Kawchuk LM, Holley JD, Lynch DR, Clear RM. Resistance to thiabendazole and thiophanate-methyl in canadian isolates of Fusarium sambucinum and Helminthosporium solani American Potato Journal. 71: 185-192. DOI: 10.1007/BF02849053  0.039
1992 Boyse WE, Lynch DR, Paulsen KD, Minerbo GN. Nodal-Based Finite-Element Modeling of Maxwell's Equations Ieee Transactions On Antennas and Propagation. 40: 642-651. DOI: 10.1109/8.144598  0.039
2004 Lynch DR, Smith KW. Wind-based convolution in limited-area coastal ocean forecasting Developments in Water Science. 55: 1801-1811. DOI: 10.1016/S0167-5648(04)80186-2  0.039
1997 Lynch DR. The nature of occupational stress among public defenders Justice System Journal. 19: 31-34.  0.039
1989 Werner FE, Lynch DR. Harmonic structure of English Channel/Southern Bight tides from a wave equation simulation Advances in Water Resources. 12: 121-142. DOI: 10.1016/0309-1708(89)90018-3  0.039
1977 Lynch DR, Rowberry RG. Population density studies with Russet Burbank I. Yield/stem density models American Potato Journal. 54: 43-56. DOI: 10.1007/BF02851873  0.038
2003 Lynch DR, Kawchuk LM, Yada R, Armstrong JD. Inheritance of the response of fry color to low temperature storage American Journal of Potato Research. 80: 341-344. DOI: 10.1007/Bf02854319  0.038
2012 Ortman SA, Huerter CJ, Lynch D, Olson D, Sarma DP. Indurated vascular plaques on the legs of an 85-year-old woman. Dermatology Online Journal. 18: 14. PMID 22483525  0.038
1989 Lynch DR, Nelson GA, Kulcsar F. Elimination of bacterial ring rot (Corynebacterium sepedonicum [Spieck. and Kotth.] Skapt. and Burkh.) by in vitro culture of sprout tissue Potato Research. 32: 341-345. DOI: 10.1007/BF02357846  0.038
2007 Jha MK, Lynch DR. Role of globalization and sustainable engineering practice in the future civil engineering education Wit Transactions On Ecology and the Environment. 102: 641-650. DOI: 10.2495/SDP070622  0.038
1988 Paulsen KD, Lynch DR, Strohbehn JW. Three-Dimensional Finite, Boundary, and Hybrid Element Solutions of the Maxwell Equations for Lossy Dielectric Media Ieee Transactions On Microwave Theory and Techniques. 36: 682-693. DOI: 10.1109/22.3572  0.038
2002 Lynch DR, Farmer JM. Neurogenetics. Introduction. Neurologic Clinics. 20: xi-xii. PMID 12432822 DOI: 10.1016/S0733-8619(02)00006-3  0.038
1988 Paulsen KD, Strohbehn JW, Lynch DR. Theoretical Electric Field Distributions Produced by Three Types of Regional Hyperthermia Devices in a Three-Dimensional Homogeneous Model of Man Ieee Transactions On Biomedical Engineering. 35: 36-45. PMID 3338810 DOI: 10.1109/10.1334  0.037
1992 Naimie CE, Lynch DR. Applications of the nonlinear three-dimensional shallow water equations to a coastal ocean Finite Elements in Water Resources, Proceedings of the International Conference. 2: 589-608.  0.037
1993 Werner FE, Blanton JO, Lynch DR, Savidge DK. A numerical study of the continental shelf circulation of the U.S. South Atlantic Bight during the autumn of 1987 Continental Shelf Research. 13: 971-997. DOI: 10.1016/0278-4343(93)90019-T  0.037
1991 Lynch DR, Coleman MC, Lyon GD. Effect of Alternaria solani culture filtrate on adventitious shoot regeneration in potato. Plant Cell Reports. 9: 607-10. PMID 24213659 DOI: 10.1007/BF00231798  0.037
1992 Paulsen KD, Boyse WE, Lynch DR. Continuous Potential Maxwell Solutions on Nodal-Based Finite Elements Ieee Transactions On Antennas and Propagation. 40: 1192-1200. DOI: 10.1109/8.182451  0.037
2024 Goodman DC, Stuchlik P, Ganduglia-Cazaban C, Tyson JE, Leyenaar J, Avritscher EBC, Rysavy M, Gautham KS, Lynch D, Stukel TA. Hospital-Level NICU Capacity, Utilization, and 30-Day Outcomes in Texas. Jama Network Open. 7: e2355982. PMID 38353952 DOI: 10.1001/jamanetworkopen.2023.55982  0.036
2004 Lynch DR. A human rights challenge to the engineering profession ethical dimensions and leadership opportunities in professional formation Asee Annual Conference Proceedings. 6629-6637.  0.035
1982 Straub WA, Lynch DR. Models of landfill leaching: moisture flow and inorganic strength Journal of the Environmental Engineering Division - Asce. 108: 231-250.  0.035
1983 Baron JA, Lynch DR, Iskandar IK. OPTIMIZATION MODEL FOR LAND TREATMENT PLANNING, DESIGN AND OPERATION PART I. BACKGROUND AND LITERATURE REVIEW Crrel Special Report (Us Army Cold Regions Research and Engineering Laboratory) 0.035
1962 Lynch DR. Electronic Devices for Measuring Flow Ire Transactions On Industrial Electronics. 22-30. DOI: 10.1109/IRE-IE.1962.5007083  0.034
1985 Lynch DR, Officer CB. Analytical test cases for three-dimensional hydrodynamic models International Journal For Numerical Methods in Fluids. 5: 529-543.  0.034
2013 Lynch D. To hell and back review: brain on fire: my month of madness. Cerebrum : the Dana Forum On Brain Science. 2013: 8. PMID 23847715  0.034
2019 Thompson M, Lynch D. When nucleated RBCs "count" in the peripheral blood: a unique case of post-essential thrombocythemia myelofibrosis. Blood. 133: 1696. PMID 30975644 DOI: 10.1182/blood-2018-10-879064  0.034
2001 Naimie CE, Lynch DR. Inversion skill for limited-area shelf modeling. Part I: An OSSE case study Continental Shelf Research. 21: 1121-1137. DOI: 10.1016/S0278-4343(01)00008-5  0.034
2002 Lynch DR, Evans TD. Attributes of highly effective criminal defense negotiators Journal of Criminal Justice. 30: 387-396. DOI: 10.1016/S0047-2352(02)00153-8  0.033
1995 Lynch DR, Foroud N, Kozub GC, Fames BC. The effect of moisture stress at three growth stages on the yield, components of yield and processing quality of eight potato varieties American Potato Journal. 72: 375-385. DOI: 10.1007/BF02849334  0.033
1985 Lynch DR, Paulsen KD, Strohbehn JW. Finite element solution of Maxwell's equations for hyperthermia treatment planning Journal of Computational Physics. 58: 246-269. DOI: 10.1016/0021-9991(85)90179-2  0.033
2001 Lynch DR, Lewis CVW, Werner FE. Can Georges Bank larval cod survive on a calanoid diet? Deep-Sea Research Part Ii: Topical Studies in Oceanography. 48: 609-630. DOI: 10.1016/S0967-0645(00)00129-6  0.033
1985 Dorri B, Kadambi V, Staub FW, Lynch DR. THERMAL STRESS ANALYSIS OF SINTERING USING A MOVING GRID . 1: 610-621.  0.032
1983 Lynch DR. Progress in hydrodynamic modeling ( USA) Reviews of Geophysics &Amp; Space Physics. 21: 741-754.  0.032
1991 Lynch DR, Paulsen KD. Origin of Vector Parasites in Numerical Maxwell Solutions Ieee Transactions On Microwave Theory and Techniques. 39: 383-394. DOI: 10.1109/22.75279  0.032
2003 Lynch DR, Kawchuk LM, Chen Q, Kokko M. Resistance to Fusarium sambucinum in Wild and Cultivated Solanum Species American Journal of Potato Research. 80: 353-358.  0.031
1981 Officer CB, Lynch DR. Dynamics of mixing in estuaries Estuarine, Coastal and Shelf Science. 12: 525-533. DOI: 10.1016/S0302-3524(81)80079-5  0.031
2020 Needs T, Lynch D. Unexpected aetiology of chronic thrombocytopaenia. Journal of Clinical Pathology. PMID 32102802 DOI: 10.1136/jclinpath-2019-206289  0.03
1993 Foroud N, Lynch DR, Entz T. Potato water content impact on soil moisture measurement by neutron meter Plant and Soil. 148: 101-106. DOI: 10.1007/BF02185389  0.03
1978 Lynch DR, Gray WG. Analytic solutions for computer flow model testing J. Hydraul. Div.: Proc. Asce. 104: 1409-1428.  0.029
1988 Lynch DR, Werner FE. Long term simulation and harmonic analysis of North Sea/English Channel Tides In: Computational Methods in Water Resources. 1. DOI: 10.1016/S0167-5648(08)70347-2  0.029
1992 Foreman MGG, Thomson RE, Lynch DR, Walters RA. Finite element model for three-dimensional flows along the west coast of Vancouver Island . 574-585.  0.029
2001 Lynch DR, McGillicuddy DJ. Objective analysis for coastal regimes Continental Shelf Research. 21: 1299-1315. DOI: 10.1016/S0278-4343(01)00007-3  0.029
1993 Lynch DR, Paulsen KD, Boyse WE. Synthesis of Vector Parasites in Finite Element Maxwell Solutions Ieee Transactions On Microwave Theory and Techniques. 41: 1439-1448. DOI: 10.1109/22.241686  0.029
1998 Ip JTC, Lynch DR, Friedrichs CT. Simulation of estuarine flooding and dewatering with application to Great Bay, New Hampshire Estuarine, Coastal and Shelf Science. 47: 119-141. DOI: 10.1006/Ecss.1998.0352  0.029
1979 Gray WG, Lynch DR. On the control of noise in finite element tidal computations: A semi-implicit approach Computers and Fluids. 7: 47-67. DOI: 10.1016/0045-7930(79)90005-7  0.028
2002 Lynch DR, Naimie CE. Hindcasting the Georges Bank circulation, Part II: Wind-band inversion Continental Shelf Research. 22: 2191-2224. DOI: 10.1016/S0278-4343(02)00072-9  0.028
2007 Lynch DR, Farmer JM, Wilson RB. Mortality in Friedreich's Ataxia. Texas Heart Institute Journal / From the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 34: 502-3; author reply . PMID 18172544  0.028
2023 Lynch D, Boccaccio D, de la Paz A, Lau-Julien C, Mournighan K, Spangler H, Dale MC, Hanson LC, Batsis JA. Increasing inpatient mobility: A path to overcoming challenges with implementation. Journal of the American Geriatrics Society. PMID 37728334 DOI: 10.1111/jgs.18578  0.028
1982 Officer CB, Lynch DR. Interpretation procedures for the determination of sediment parameters from time-dependent flux inputs Earth and Planetary Science Letters. 61: 55-62. DOI: 10.1016/0012-821X(82)90037-1  0.027
1984 Lynch DR, Officer CB. Nonlinear parameter estimation for sediment cores Chemical Geology. 44: 203-225. DOI: 10.1016/0009-2541(84)90073-1  0.027
1978 Lynch DR, Gray WG. Finite elements simulation of shallow water problems with moving boundaries 0.027
1991 Paulsen KD, Lynch DR. Elimination of Vector Parasites in Finite Element Maxwell Solutions Ieee Transactions On Microwave Theory and Techniques. 39: 395-404. DOI: 10.1109/22.75280  0.027
1988 Mains WH, Ethier DJ, Lynch DR. Automated, variable speed PTO for a plot-sized potato harvester American Potato Journal. 65: 365-368. DOI: 10.1007/BF02853532  0.027
1992 Lynch DR, Hutchinson CE. Environmental education Proceedings of the National Academy of Sciences of the United States of America. 89: 864-867.  0.026
1990 Lynch DR, Paulsen KD. Time-Domain Integration of the Maxwell Equations on Finite Elements Ieee Transactions On Antennas and Propagation. 38: 1933-1942. DOI: 10.1109/8.60982  0.026
1993 Paulsen KD, Lynch DR, Boyse WE, Minerbo GN. Applications of Potentials to Finite Element Modeling of Maxwell’s Equations Ieee Transactions On Magnetics. 29: 1333-1336. DOI: 10.1109/20.250644  0.026
1984 Gray WG, Lynch DR. Time-stepping schemes for finite element tidal model computations . DOI: 10.1016/0309-1708(77)90026-4  0.026
1983 Baron JA, Lynch DR. OPTIMIZATION MODEL FOR LAND TREATMENT PLANNING, DESIGN AND OPERATION PART III. MODEL DESCRIPTION AND USER'S GUIDE Crrel Special Report (Us Army Cold Regions Research and Engineering Laboratory) 0.025
1982 Lynch DR. Unified approach to simulation on deforming elements with application to phase change problems Journal of Computational Physics. 47: 387-411. DOI: 10.1016/0021-9991(82)90090-0  0.025
2009 Smith KW, McGillicuddy DJ, Lynch DR. Parameter estimation using an ensemble smoother: The effect of the circulation in biological estimation Journal of Marine Systems. 76: 162-170. DOI: 10.1016/J.Jmarsys.2008.05.017  0.025
2001 Naimie CE, Ann Blain C, Lynch DR. Seasonal mean circulation in the Yellow Sea - A model-generated climatology Continental Shelf Research. 21: 667-695. DOI: 10.1016/S0278-4343(00)00102-3  0.025
1987 Lynch DR, Werner FE. Three dimensional hydrodynamics on finite elements. Part 1: linearized harmonic model Int. J. Numer. Methods Fluids. 7.  0.025
1986 Lynch DR, Werner FE. Three-dimensional harmonic model for linearized tidal circulation 0.024
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