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Dennis S. Charney - Publications

Affiliations: 
Neurosciences Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Neuroscience Biology, Mental Health, Clinical Psychology
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Year Citation  Score
2022 Cathomas F, Bevilacqua L, Ramakrishnan A, Kronman H, Costi S, Schneider M, Chan KL, Li L, Nestler EJ, Shen L, Charney DS, Russo SJ, Murrough JW. Whole blood transcriptional signatures associated with rapid antidepressant response to ketamine in patients with treatment resistant depression. Translational Psychiatry. 12: 12. PMID 35013133 DOI: 10.1038/s41398-021-01712-0  0.597
2020 Paranjpe I, Russak AJ, De Freitas JK, Lala A, Miotto R, Vaid A, Johnson KW, Danieletto M, Golden E, Meyer D, Singh M, Somani S, Kapoor A, O'Hagan R, Manna S, ... ... Charney D, et al. Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City. Bmj Open. 10: e040736. PMID 33247020 DOI: 10.1136/bmjopen-2020-040736  0.329
2020 Vaid A, Somani S, Russak AJ, De Freitas JK, Chaudhry FF, Paranjpe I, Johnson KW, Lee SJ, Miotto R, Richter F, Zhao S, Beckmann ND, Naik N, Kia A, Timsina P, ... ... Charney DS, et al. Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients: A Cohort Study. Journal of Medical Internet Research. PMID 33027032 DOI: 10.2196/24018  0.338
2020 Feder A, Rutter SB, Schiller D, Charney DS. The emergence of ketamine as a novel treatment for posttraumatic stress disorder. Advances in Pharmacology (San Diego, Calif.). 89: 261-286. PMID 32616209 DOI: 10.1016/Bs.Apha.2020.05.004  0.374
2020 Paranjpe I, Russak A, De Freitas JK, Lala A, Miotto R, Vaid A, Johnson KW, Danieletto M, Golden E, Meyer D, Singh M, Somani S, Manna S, Nangia U, Kapoor A, ... ... Charney DS, et al. Clinical Characteristics of Hospitalized Covid-19 Patients in New York City. Medrxiv : the Preprint Server For Health Sciences. PMID 32511655 DOI: 10.1101/2020.04.19.20062117  0.327
2020 Krystal JH, Charney DS, Duman RS. A New Rapid-Acting Antidepressant. Cell. 181: 7. PMID 32243798 DOI: 10.1016/J.Cell.2020.02.033  0.488
2020 Morris LS, Tan A, Smith DA, Grehl M, Han-Huang K, Naidich TP, Charney DS, Balchandani P, Murrough JW, Kundu P. Sub-millimeter variation in human locus coeruleus is associated with dimensional measures of psychopathology: An in vivo ultra-high field 7-Tesla MRI study. Neuroimage. Clinical. 25: 102148. PMID 32097890 DOI: 10.1016/J.Nicl.2019.102148  0.343
2020 Morris LS, Costi S, Tan A, Stern ER, Charney D, Murrough JW. Ketamine normalizes subgenual cingulate cortex hyper-activity in depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31896116 DOI: 10.1038/S41386-019-0591-5  0.391
2019 Jha MK, Qamar A, Vaduganathan M, Charney DS, Murrough JW. Screening and Management of Depression in Patients With Cardiovascular Disease: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 73: 1827-1845. PMID 30975301 DOI: 10.1016/J.Jacc.2019.01.041  0.322
2019 Costi S, Soleimani L, Glasgow A, Brallier J, Spivack J, Schwartz J, Levitch CF, Richards S, Hoch M, Wade E, Welch A, Collins KA, Feder A, Iosifescu DV, Charney DS, et al. Lithium continuation therapy following ketamine in patients with treatment resistant unipolar depression: a randomized controlled trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30858518 DOI: 10.1038/S41386-019-0365-0  0.384
2019 Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS. Ketamine: A Paradigm Shift for Depression Research and Treatment. Neuron. 101: 774-778. PMID 30844397 DOI: 10.1016/J.Neuron.2019.02.005  0.661
2018 Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Gruenbaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, et al. Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Translational Psychiatry. 8: 280. PMID 30552317 DOI: 10.1038/S41398-018-0311-7  0.39
2018 Reuveni I, Nugent AC, Gill J, Vythilingam M, Carlson PJ, Lerner A, Neumeister A, Charney DS, Drevets WC, Bonne O. Altered cerebral benzodiazepine receptor binding in post-traumatic stress disorder. Translational Psychiatry. 8: 206. PMID 30287828 DOI: 10.1038/S41398-018-0257-9  0.345
2017 Sayed S, Van Dam NT, Horn SR, Kautz MM, Parides M, Costi S, Collins KA, Iacoviello B, Iosifescu DV, Mathé AA, Southwick SM, Feder A, Charney DS, Murrough JW. A randomized dose-ranging study of neuropeptide Y in patients with posttraumatic stress disorder. The International Journal of Neuropsychopharmacology. PMID 29186416 DOI: 10.1093/Ijnp/Pyx109  0.356
2017 Murrough JW, Wade E, Sayed S, Ahle G, Kiraly DD, Welch A, Collins KA, Soleimani L, Iosifescu DV, Charney DS. Dextromethorphan/quinidine pharmacotherapy in patients with treatment resistant depression: A proof of concept clinical trial. Journal of Affective Disorders. 218: 277-283. PMID 28478356 DOI: 10.1016/J.Jad.2017.04.072  0.38
2017 Kiraly DD, Horn SR, Van Dam NT, Costi S, Schwartz J, Kim-Schulze S, Patel M, Hodes GE, Russo SJ, Merad M, Iosifescu DV, Charney DS, Murrough JW. Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome. Translational Psychiatry. 7: e1065. PMID 28323284 DOI: 10.1038/Tp.2017.31  0.57
2017 Dalgard C, Eidelman O, Jozwik C, Olsen CH, Srivastava M, Biswas R, Eudy Y, Rothwell SW, Mueller GP, Yuan P, Drevets WC, Manji HK, Vythlingam M, Charney DS, Neumeister A, et al. The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder. Translational Psychiatry. 7: e1025. PMID 28170001 DOI: 10.1038/Tp.2016.285  0.352
2017 Murrough J, Sayed S, Van Dam N, Horn S, Kautz M, Parides M, Iacoviello B, Costi S, Collins K, Iosifescu D, Southwick S, Mathé A, Feder A, Charney D. 171. A Randomized Controlled Dose-Ranging Study of Intranasal Administration of Neuropeptide Y in Patients with Posttraumatic Stress Disorder Biological Psychiatry. 81: S71. DOI: 10.1016/J.Biopsych.2017.02.184  0.331
2016 Kautz M, Charney DS, Murrough JW. Neuropeptide Y, resilience, and PTSD therapeutics. Neuroscience Letters. PMID 27913193 DOI: 10.1016/J.Neulet.2016.11.061  0.327
2016 Abdallah CG, Averill LA, Collins KA, Geha P, Schwartz J, Averill C, DeWilde KE, Wong E, Anticevic A, Tang CY, Iosifescu DV, Charney DS, Murrough JW. Ketamine Treatment and Global Brain Connectivity in Major Depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27604566 DOI: 10.1038/Npp.2016.186  0.383
2016 Murrough JW, Abdallah CG, Anticevic A, Collins KA, Geha P, Averill LA, Schwartz J, DeWilde KE, Averill C, Jia-Wei Yang G, Wong E, Tang CY, Krystal JH, Iosifescu DV, Charney DS. Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder. Human Brain Mapping. PMID 27144347 DOI: 10.1002/Hbm.23235  0.506
2016 Southwick SM, Sippel L, Krystal J, Charney D, Mayes L, Pietrzak R. Why are some individuals more resilient than others: the role of social support. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 15: 77-9. PMID 26833614 DOI: 10.1002/Wps.20282  0.372
2016 Wald I, Bitton S, Levi O, Zusmanovich S, Fruchter E, Ginat K, Charney DS, Pine DS, Bar-Haim Y. Acute Delivery of Attention Bias Modification Training (ABMT) Moderates the Association between Combat Exposure and Posttraumatic Symptoms: A Feasibility Study. Biological Psychology. PMID 26780267 DOI: 10.1016/J.Biopsycho.2016.01.005  0.456
2015 Southwick SM, Pietrzak RH, Charney DS, Krystal JH. Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors. The Behavioral and Brain Sciences. 38: e122. PMID 26786005 DOI: 10.1017/S0140525X14001708  0.399
2015 Murrough JW, Soleimani L, DeWilde KE, Collins KA, Lapidus KA, Iacoviello BM, Lener M, Kautz M, Kim J, Stern JB, Price RB, Perez AM, Brallier JW, Rodriguez GJ, Goodman WK, ... ... Charney DS, et al. Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial. Psychological Medicine. 1-10. PMID 26266877 DOI: 10.1017/S0033291715001506  0.329
2015 Murrough JW, Yaqubi S, Sayed S, Charney DS. Emerging drugs for the treatment of anxiety. Expert Opinion On Emerging Drugs. 20: 393-406. PMID 26012843 DOI: 10.1517/14728214.2015.1049996  0.332
2015 Homan P, Neumeister A, Nugent AC, Charney DS, Drevets WC, Hasler G. Serotonin versus catecholamine deficiency: behavioral and neural effects of experimental depletion in remitted depression. Translational Psychiatry. 5: e532. PMID 25781231 DOI: 10.1038/Tp.2015.25  0.365
2015 Murrough JW, Collins KA, Fields J, DeWilde KE, Phillips ML, Mathew SJ, Wong E, Tang CY, Charney DS, Iosifescu DV. Regulation of neural responses to emotion perception by ketamine in individuals with treatment-resistant major depressive disorder. Translational Psychiatry. 5: e509. PMID 25689570 DOI: 10.1038/Tp.2015.10  0.385
2015 Murrough JW, Burdick KE, Levitch CF, Perez AM, Brallier JW, Chang LC, Foulkes A, Charney DS, Mathew SJ, Iosifescu DV. Neurocognitive effects of ketamine and association with antidepressant response in individuals with treatment-resistant depression: a randomized controlled trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1084-90. PMID 25374095 DOI: 10.1038/Npp.2014.298  0.388
2015 Wan LB, Levitch CF, Perez AM, Brallier JW, Iosifescu DV, Chang LC, Foulkes A, Mathew SJ, Charney DS, Murrough JW. Ketamine safety and tolerability in clinical trials for treatment-resistant depression. The Journal of Clinical Psychiatry. 76: 247-52. PMID 25271445 DOI: 10.4088/Jcp.13M08852  0.326
2015 Hasler G, Homan P, Neumeister A, Nugent A, Charney D, Drevets W. Differenital Behavioral and Neural Consequences of Serotonin and Catecholamine Deficiency in Depression: an Experimental Study European Psychiatry. 30: 1302. DOI: 10.1016/S0924-9338(15)31019-1  0.358
2014 Lapidus KA, Levitch CF, Perez AM, Brallier JW, Parides MK, Soleimani L, Feder A, Iosifescu DV, Charney DS, Murrough JW. A randomized controlled trial of intranasal ketamine in major depressive disorder. Biological Psychiatry. 76: 970-6. PMID 24821196 DOI: 10.1016/J.Biopsych.2014.03.026  0.379
2014 Iacoviello BM, Wu G, Alvarez E, Huryk K, Collins KA, Murrough JW, Iosifescu DV, Charney DS. Cognitive-emotional training as an intervention for major depressive disorder. Depression and Anxiety. 31: 699-706. PMID 24753225 DOI: 10.1002/Da.22266  0.31
2014 Feder A, Parides MK, Murrough JW, Perez AM, Morgan JE, Saxena S, Kirkwood K, Aan Het Rot M, Lapidus KA, Wan LB, Iosifescu D, Charney DS. Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial. Jama Psychiatry. 71: 681-8. PMID 24740528 DOI: 10.1001/Jamapsychiatry.2014.62  0.383
2014 Iacoviello BM, Wu G, Abend R, Murrough JW, Feder A, Fruchter E, Levinstein Y, Wald I, Bailey CR, Pine DS, Neumeister A, Bar-Haim Y, Charney DS. Attention bias variability and symptoms of posttraumatic stress disorder. Journal of Traumatic Stress. 27: 232-9. PMID 24604631 DOI: 10.1002/Jts.21899  0.483
2014 Niciu MJ, Henter ID, Luckenbaugh DA, Zarate CA, Charney DS. Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds. Annual Review of Pharmacology and Toxicology. 54: 119-39. PMID 24392693 DOI: 10.1146/Annurev-Pharmtox-011613-135950  0.356
2014 Haile CN, Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Foulkes A, Iqbal S, Mahoney JJ, De La Garza R, Charney DS, Newton TF, Mathew SJ. Plasma brain derived neurotrophic factor (BDNF) and response to ketamine in treatment-resistant depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 331-6. PMID 24103211 DOI: 10.1017/S1461145713001119  0.332
2014 Haile CN, Murrough J, Iosifescu D, Chang L, Jurdi RA, Foulkes A, Iqbal S, Mahoney JJ, Garza RDL, Charney D, Newton TF, Mathew S. Ketamine for treatment-resistant depression: Subjective effects and impact on plasma brain-derived neurotrophic factor Drug and Alcohol Dependence. 140: e77. DOI: 10.1016/J.Drugalcdep.2014.02.230  0.324
2013 Murrough JW, Wan LB, Iacoviello B, Collins KA, Solon C, Glicksberg B, Perez AM, Mathew SJ, Charney DS, Iosifescu DV, Burdick KE. Neurocognitive effects of ketamine in treatment-resistant major depression: association with antidepressant response. Psychopharmacology. PMID 24022236 DOI: 10.1007/S00213-013-3255-X  0.355
2013 Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Green CE, Perez AM, Iqbal S, Pillemer S, Foulkes A, Shah A, Charney DS, Mathew SJ. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. The American Journal of Psychiatry. 170: 1134-42. PMID 23982301 DOI: 10.1176/Appi.Ajp.2013.13030392  0.344
2013 Russo SJ, Charney DS. Next generation antidepressants. Proceedings of the National Academy of Sciences of the United States of America. 110: 4441-2. PMID 23471996 DOI: 10.1073/Pnas.1301593110  0.596
2013 Wald I, Degnan KA, Gorodetsky E, Charney DS, Fox NA, Fruchter E, Goldman D, Lubin G, Pine DS, Bar-Haim Y. Attention to threats and combat-related posttraumatic stress symptoms: prospective associations and moderation by the serotonin transporter gene. Jama Psychiatry. 70: 401-8. PMID 23407816 DOI: 10.1001/2013.Jamapsychiatry.188  0.461
2013 Feder A, Ahmad S, Lee EJ, Morgan JE, Singh R, Smith BW, Southwick SM, Charney DS. Coping and PTSD symptoms in Pakistani earthquake survivors: purpose in life, religious coping and social support. Journal of Affective Disorders. 147: 156-63. PMID 23196198 DOI: 10.1016/J.Jad.2012.10.027  0.357
2013 Murrough JW, Perez AM, Pillemer S, Stern J, Parides MK, aan het Rot M, Collins KA, Mathew SJ, Charney DS, Iosifescu DV. Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biological Psychiatry. 74: 250-6. PMID 22840761 DOI: 10.1016/J.Biopsych.2012.06.022  0.371
2013 Blair KS, Vythilingam M, Crowe SL, McCaffrey DE, Ng P, Wu CC, Scaramozza M, Mondillo K, Pine DS, Charney DS, Blair RJ. Cognitive control of attention is differentially affected in trauma-exposed individuals with and without post-traumatic stress disorder. Psychological Medicine. 43: 85-95. PMID 22571775 DOI: 10.1017/S0033291712000840  0.475
2012 Russo SJ, Murrough JW, Han MH, Charney DS, Nestler EJ. Neurobiology of resilience. Nature Neuroscience. 15: 1475-84. PMID 23064380 DOI: 10.1038/Nn.3234  0.609
2012 Southwick SM, Charney DS. The science of resilience: implications for the prevention and treatment of depression. Science (New York, N.Y.). 338: 79-82. PMID 23042887 DOI: 10.1126/Science.1222942  0.366
2012 Murrough JW, Charney DS. Is there anything really novel on the antidepressant horizon? Current Psychiatry Reports. 14: 643-9. PMID 22996298 DOI: 10.1007/S11920-012-0321-8  0.362
2012 Aan Het Rot M, Zarate CA, Charney DS, Mathew SJ. Ketamine for depression: where do we go from here? Biological Psychiatry. 72: 537-47. PMID 22705040 DOI: 10.1016/J.Biopsych.2012.05.003  0.376
2012 Gold PW, Pavlatou MG, Carlson PJ, Luckenbaugh DA, Costello R, Bonne O, Csako G, Drevets WC, Remaley AT, Charney DS, Neumeister A, Kling MA. Unmedicated, remitted patients with major depression have decreased serum immunoglobulin A. Neuroscience Letters. 520: 1-5. PMID 22579817 DOI: 10.1016/J.Neulet.2012.04.072  0.346
2012 Morgan J, Calderon S, Lebow M, Iosifescu D, Charney D, Feder A. Childhood trauma and comorbid mood and anxiety disorders in adult patients with post-traumatic stress disorder European Journal of Psychotraumatology. 3. DOI: 10.3402/Ejpt.V3I0.19567  0.356
2011 Wu G, Feder A, Wegener G, Bailey C, Saxena S, Charney D, Mathé AA. Central functions of neuropeptide Y in mood and anxiety disorders. Expert Opinion On Therapeutic Targets. 15: 1317-31. PMID 21995655 DOI: 10.1517/14728222.2011.628314  0.323
2011 Murrough JW, Iacoviello B, Neumeister A, Charney DS, Iosifescu DV. Cognitive dysfunction in depression: Neurocircuitry and new therapeutic strategies Neurobiology of Learning and Memory. 96: 553-563. PMID 21704176 DOI: 10.1016/J.Nlm.2011.06.006  0.333
2011 Murrough JW, Perez AM, Mathew SJ, Charney DS. A case of sustained remission following an acute course of ketamine in treatment-resistant depression. The Journal of Clinical Psychiatry. 72: 414-5. PMID 21450159 DOI: 10.4088/Jcp.10L06447Blu  0.306
2011 Wald I, Shechner T, Bitton S, Holoshitz Y, Charney DS, Muller D, Fox NA, Pine DS, Bar-Haim Y. Attention bias away from threat during life threatening danger predicts PTSD symptoms at one-year follow-up. Depression and Anxiety. 28: 406-11. PMID 21381159 DOI: 10.1002/Da.20808  0.478
2011 Feder A, Skipper J, Blair JR, Buchholz K, Mathew SJ, Schwarz M, Doucette JT, Alonso A, Collins KA, Neumeister A, Charney DS. Tryptophan depletion and emotional processing in healthy volunteers at high risk for depression. Biological Psychiatry. 69: 804-7. PMID 21377656 DOI: 10.1016/J.Biopsych.2010.12.033  0.343
2011 Bonne O, Gill JM, Luckenbaugh DA, Collins C, Owens MJ, Alesci S, Neumeister A, Yuan P, Kinkead B, Manji HK, Charney DS, Vythilingam M. Corticotropin-releasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine. The Journal of Clinical Psychiatry. 72: 1124-8. PMID 21208596 DOI: 10.4088/Jcp.09M05106Blu  0.353
2011 Mathew SJ, Vythilingam M, Murrough JW, Zarate CA, Feder A, Luckenbaugh DA, Kinkead B, Parides MK, Trist DG, Bani MS, Bettica PU, Ratti EM, Charney DS. A selective neurokinin-1 receptor antagonist in chronic PTSD: a randomized, double-blind, placebo-controlled, proof-of-concept trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 221-9. PMID 21194898 DOI: 10.1016/J.Euroneuro.2010.11.012  0.326
2011 Wald I, Lubin G, Holoshitz Y, Muller D, Fruchter E, Pine DS, Charney DS, Bar-Haim Y. Battlefield-like stress following simulated combat and suppression of attention bias to threat. Psychological Medicine. 41: 699-707. PMID 21108868 DOI: 10.1017/S0033291710002308  0.465
2011 Savitz JB, Nugent AC, Bogers W, Roiser JP, Bain EE, Neumeister A, Zarate CA, Manji HK, Cannon DM, Marrett S, Henn F, Charney DS, Drevets WC. Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study. Biological Psychiatry. 69: 336-43. PMID 21094939 DOI: 10.1016/J.Biopsych.2010.09.027  0.401
2011 Murrough JW, Gallo JM, Collins KA, Aan Het Rot M, Charney DS. Reply to: Dose- and exposure-response to ketamine in depression Biological Psychiatry. 70: e11-e12. DOI: 10.1016/J.Biopsych.2011.02.018  0.309
2010 Gill J, Luckenbaugh D, Charney D, Vythilingam M. Sustained elevation of serum interleukin-6 and relative insensitivity to hydrocortisone differentiates posttraumatic stress disorder with and without depression. Biological Psychiatry. 68: 999-1006. PMID 20951370 DOI: 10.1016/J.Biopsych.2010.07.033  0.367
2010 Krystal JH, Mathew SJ, D'Souza DC, Garakani A, Gunduz-Bruce H, Charney DS. Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists. Cns Drugs. 24: 669-93. PMID 20658799 DOI: 10.2165/11533230-000000000-00000  0.511
2010 Bar-Haim Y, Holoshitz Y, Eldar S, Frenkel TI, Muller D, Charney DS, Pine DS, Fox NA, Wald I. Life-threatening danger and suppression of attention bias to threat. The American Journal of Psychiatry. 167: 694-8. PMID 20395400 DOI: 10.1176/Appi.Ajp.2009.09070956  0.492
2010 Savitz J, Nugent AC, Bogers W, Liu A, Sills R, Luckenbaugh DA, Bain EE, Price JL, Zarate C, Manji HK, Cannon DM, Marrett S, Charney DS, Drevets WC. Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication. Neuroimage. 49: 2966-76. PMID 19931399 DOI: 10.1016/J.Neuroimage.2009.11.025  0.324
2010 aan het Rot M, Collins KA, Murrough JW, Perez AM, Reich DL, Charney DS, Mathew SJ. Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression. Biological Psychiatry. 67: 139-45. PMID 19897179 DOI: 10.1016/J.Biopsych.2009.08.038  0.37
2010 Vythilingam M, Gill JM, Luckenbaugh DA, Gold PW, Collin C, Bonne O, Plumb K, Polignano E, West K, Charney D. Low early morning plasma cortisol in posttraumatic stress disorder is associated with co-morbid depression but not with enhanced glucocorticoid feedback inhibition. Psychoneuroendocrinology. 35: 442-50. PMID 19766403 DOI: 10.1016/J.Psyneuen.2009.08.006  0.402
2010 Mathew SJ, Murrough JW, aan het Rot M, Collins KA, Reich DL, Charney DS. Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 71-82. PMID 19288975 DOI: 10.1017/S1461145709000169  0.359
2009 Zuo L, Luo X, Kranzler HR, Lu L, Rosenheck RA, Cramer J, van Kammen DP, Erdos J, Charney DS, Krystal J, Gelernter J. Association study of DTNBP1 with schizophrenia in a US sample. Psychiatric Genetics. 19: 292-304. PMID 19862852 DOI: 10.1097/Ypg.0B013E32832A50Bc  0.413
2009 New AS, Fan J, Murrough JW, Liu X, Liebman RE, Guise KG, Tang CY, Charney DS. A Functional Magnetic Resonance Imaging Study of Deliberate Emotion Regulation in Resilience and Posttraumatic Stress Disorder Biological Psychiatry. 66: 656-664. PMID 19589502 DOI: 10.1016/J.Biopsych.2009.05.020  0.301
2009 Price RB, Nock MK, Charney DS, Mathew SJ. Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression. Biological Psychiatry. 66: 522-6. PMID 19545857 DOI: 10.1016/J.Biopsych.2009.04.029  0.331
2009 Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nature Reviews. Neuroscience. 10: 446-57. PMID 19455174 DOI: 10.1038/Nrn2649  0.475
2009 Hasler G, Luckenbaugh DA, Snow J, Meyers N, Waldeck T, Geraci M, Roiser J, Knutson B, Charney DS, Drevets WC. Reward processing after catecholamine depletion in unmedicated, remitted subjects with major depressive disorder. Biological Psychiatry. 66: 201-5. PMID 19393989 DOI: 10.1016/J.Biopsych.2009.02.029  0.356
2009 Zuo L, Luo X, Krystal JH, Cramer J, Charney DS, Gelernter J. The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation. Pharmacogenetics and Genomics. 19: 437-46. PMID 19369910 DOI: 10.1097/Fpc.0B013E32832B9Cfc  0.436
2009 Zuo L, Luo X, Listman JB, Kranzler HR, Wang S, Anton RF, Blumberg HP, Stein MB, Pearlson GD, Covault J, Charney DS, van Kammen DP, Price LH, Lappalainen J, Cramer J, et al. Population admixture modulates risk for alcohol dependence. Human Genetics. 125: 605-13. PMID 19306106 DOI: 10.1007/S00439-009-0647-4  0.588
2009 Vasa RA, Pine DS, Masten CL, Vythilingam M, Collin C, Charney DS, Neumeister A, Mogg K, Bradley BP, Bruck M, Monk CS. Effects of yohimbine and hydrocortisone on panic symptoms, autonomic responses, and attention to threat in healthy adults. Psychopharmacology. 204: 445-55. PMID 19266185 DOI: 10.1007/S00213-009-1475-X  0.651
2009 Vythilingam M, Nelson EE, Scaramozza M, Waldeck T, Hazlett G, Southwick SM, Pine DS, Drevets W, Charney DS, Ernst M. Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers. Psychiatry Research. 172: 75-7. PMID 19243926 DOI: 10.1016/J.Pscychresns.2008.06.008  0.415
2009 aan het Rot M, Mathew SJ, Charney DS. Neurobiological mechanisms in major depressive disorder. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 180: 305-13. PMID 19188629 DOI: 10.1503/Cmaj.080697  0.361
2009 Price RB, Shungu DC, Mao X, Nestadt P, Kelly C, Collins KA, Murrough JW, Charney DS, Mathew SJ. Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder. Biological Psychiatry. 65: 792-800. PMID 19058788 DOI: 10.1016/J.Biopsych.2008.10.025  0.342
2008 Nugent AC, Neumeister A, Goldman D, Herscovitch P, Charney DS, Drevets WC. Serotonin transporter genotype and depressive phenotype determination by discriminant analysis of glucose metabolism under acute tryptophan depletion. Neuroimage. 43: 764-74. PMID 18718871 DOI: 10.1016/J.Neuroimage.2008.07.040  0.355
2008 Mathew S, Charney D. Anxiety and depression: Leading edge of therapy Mount Sinai Journal of Medicine. 75: 171-173. PMID 18704975 DOI: 10.1002/Msj.20049  0.322
2008 Bonne O, Vythilingam M, Inagaki M, Wood S, Neumeister A, Nugent AC, Snow J, Luckenbaugh DA, Bain EE, Drevets WC, Charney DS. Reduced posterior hippocampal volume in posttraumatic stress disorder. The Journal of Clinical Psychiatry. 69: 1087-91. PMID 18572983 DOI: 10.4088/Jcp.V69N0707  0.312
2008 New AS, Triebwasser J, Charney DS. The case for shifting borderline personality disorder to Axis I. Biological Psychiatry. 64: 653-9. PMID 18550033 DOI: 10.1016/J.Biopsych.2008.04.020  0.32
2008 Blair K, Shaywitz J, Smith BW, Rhodes R, Geraci M, Jones M, McCaffrey D, Vythilingam M, Finger E, Mondillo K, Jacobs M, Charney DS, Blair RJ, Drevets WC, Pine DS. Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders. The American Journal of Psychiatry. 165: 1193-202. PMID 18483136 DOI: 10.1176/Appi.Ajp.2008.07071060  0.489
2008 Hasler G, Fromm S, Carlson PJ, Luckenbaugh DA, Waldeck T, Geraci M, Roiser JP, Neumeister A, Meyers N, Charney DS, Drevets WC. Neural response to catecholamine depletion in unmedicated subjects with major depressive disorder in remission and healthy subjects. Archives of General Psychiatry. 65: 521-31. PMID 18458204 DOI: 10.1001/Archpsyc.65.5.521  0.38
2008 Jacobs M, Snow J, Geraci M, Vythilingam M, Blair RJ, Charney DS, Pine DS, Blair KS. Association between level of emotional intelligence and severity of anxiety in generalized social phobia. Journal of Anxiety Disorders. 22: 1487-95. PMID 18439799 DOI: 10.1016/J.Janxdis.2008.03.003  0.427
2008 Mathew SJ, Price RB, Charney DS. Recent advances in the neurobiology of anxiety disorders: implications for novel therapeutics. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 148: 89-98. PMID 18412102 DOI: 10.1002/Ajmg.C.30172  0.382
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005  0.747
2008 Czermak C, Hauger R, Drevets WC, Luckenbaugh DA, Geraci M, Charney DS, Neumeister A. Plasma NPY concentrations during tryptophan and sham depletion in medication-free patients with remitted depression. Journal of Affective Disorders. 110: 277-81. PMID 18281099 DOI: 10.1016/J.Jad.2008.01.014  0.342
2008 Lekman M, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ, Paddock S. The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biological Psychiatry. 63: 1103-10. PMID 18191112 DOI: 10.1016/J.Biopsych.2007.10.026  0.344
2008 Mathew SJ, Manji HK, Charney DS. Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2080-92. PMID 18172433 DOI: 10.1038/Sj.Npp.1301652  0.324
2008 Masten CL, Guyer AE, Hodgdon HB, McClure EB, Charney DS, Ernst M, Kaufman J, Pine DS, Monk CS. Recognition of facial emotions among maltreated children with high rates of post-traumatic stress disorder. Child Abuse & Neglect. 32: 139-53. PMID 18155144 DOI: 10.1016/J.Chiabu.2007.09.006  0.729
2008 Mathew SJ, Price RB, Mao X, Smith EL, Coplan JD, Charney DS, Shungu DC. Hippocampal N-acetylaspartate concentration and response to riluzole in generalized anxiety disorder. Biological Psychiatry. 63: 891-8. PMID 18028881 DOI: 10.1016/J.Biopsych.2007.09.012  0.386
2007 Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS, Manji HK, Drevets WC. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. Biological Psychiatry. 62: 870-7. PMID 17678634 DOI: 10.1016/J.Biopsych.2007.03.016  0.384
2007 Hu XZ, Rush AJ, Charney D, Wilson AF, Sorant AJ, Papanicolaou GJ, Fava M, Trivedi MH, Wisniewski SR, Laje G, Paddock S, McMahon FJ, Manji H, Lipsky RH. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Archives of General Psychiatry. 64: 783-92. PMID 17606812 DOI: 10.1001/Archpsyc.64.7.783  0.311
2007 Vythilingam M, Blair KS, McCaffrey D, Scaramozza M, Jones M, Nakic M, Mondillo K, Hadd K, Bonne O, Mitchell DG, Pine DS, Charney DS, Blair RJ. Biased emotional attention in post-traumatic stress disorder: a help as well as a hindrance? Psychological Medicine. 37: 1445-55. PMID 17559703 DOI: 10.1017/S003329170700092X  0.444
2007 Graves RE, Alim TN, Aigbogun N, Chrishon K, Mellman TA, Charney DS, Lawson WB. Diagnosing bipolar disorder in trauma exposed primary care patients. Bipolar Disorders. 9: 318-23. PMID 17547578 DOI: 10.1111/J.1399-5618.2007.00449.X  0.334
2007 McClure EB, Monk CS, Nelson EE, Parrish JM, Adler A, Blair RJ, Fromm S, Charney DS, Leibenluft E, Ernst M, Pine DS. Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder. Archives of General Psychiatry. 64: 97-106. PMID 17199059 DOI: 10.1001/Archpsyc.64.1.97  0.663
2007 Bremner JD, Vythilingam M, Vermetten E, Charney DS. Effects of antidepressant treatment on neural correlates of emotional and neutral declarative verbal memory in depression. Journal of Affective Disorders. 101: 99-111. PMID 17182108 DOI: 10.1016/J.Jad.2006.10.028  0.332
2007 Kling MA, Alesci S, Csako G, Costello R, Luckenbaugh DA, Bonne O, Duncko R, Drevets WC, Manji HK, Charney DS, Gold PW, Neumeister A. Sustained low-grade pro-inflammatory state in unmedicated, remitted women with major depressive disorder as evidenced by elevated serum levels of the acute phase proteins C-reactive protein and serum amyloid A. Biological Psychiatry. 62: 309-13. PMID 17178112 DOI: 10.1016/J.Biopsych.2006.09.033  0.302
2006 Neumeister A, Hu XZ, Luckenbaugh DA, Schwarz M, Nugent AC, Bonne O, Herscovitch P, Goldman D, Drevets WC, Charney DS. Differential effects of 5-HTTLPR genotypes on the behavioral and neural responses to tryptophan depletion in patients with major depression and controls. Archives of General Psychiatry. 63: 978-86. PMID 16953000 DOI: 10.1001/Archpsyc.63.9.978  0.379
2006 Rasmusson AM, Pinna G, Paliwal P, Weisman D, Gottschalk C, Charney D, Krystal J, Guidotti A. Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biological Psychiatry. 60: 704-13. PMID 16934764 DOI: 10.1016/J.Biopsych.2006.03.026  0.488
2006 Zarate CA, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA, Charney DS, Manji HK. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Archives of General Psychiatry. 63: 856-64. PMID 16894061 DOI: 10.1001/Archpsyc.63.8.856  0.384
2006 Vermetten E, Vythilingam M, Schmahl C, DE Kloet C, Southwick SM, Charney DS, Bremner JD. Alterations in stress reactivity after long-term treatment with paroxetine in women with posttraumatic stress disorder. Annals of the New York Academy of Sciences. 1071: 184-202. PMID 16891570 DOI: 10.1196/Annals.1364.014  0.324
2006 Cannon DM, Ichise M, Fromm SJ, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in bipolar disorder assessed using [11C]DASB and positron emission tomography. Biological Psychiatry. 60: 207-17. PMID 16875929 DOI: 10.1016/J.Biopsych.2006.05.005  0.315
2006 Kaplan JS, Erickson K, Luckenbaugh DA, Weiland-Fiedler P, Geraci M, Sahakian BJ, Charney D, Drevets WC, Neumeister A. Differential performance on tasks of affective processing and decision-making in patients with Panic Disorder and Panic Disorder with comorbid Major Depressive Disorder. Journal of Affective Disorders. 95: 165-71. PMID 16793143 DOI: 10.1016/J.Jad.2006.04.016  0.323
2006 Monk CS, Nelson EE, McClure EB, Mogg K, Bradley BP, Leibenluft E, Blair RJ, Chen G, Charney DS, Ernst M, Pine DS. Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder. The American Journal of Psychiatry. 163: 1091-7. PMID 16741211 DOI: 10.1176/Ajp.2006.163.6.1091  0.67
2006 Alim TN, Charney DS, Mellman TA. An overview of posttraumatic stress disorder in African Americans. Journal of Clinical Psychology. 62: 801-13. PMID 16703601 DOI: 10.1002/Jclp.20280  0.318
2006 Zhang H, Ozbay F, Lappalainen J, Kranzler HR, van Dyck CH, Charney DS, Price LH, Southwick S, Yang BZ, Rasmussen A, Gelernter J. Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 387-93. PMID 16649215 DOI: 10.1002/Ajmg.B.30332  0.51
2006 McMahon FJ, Buervenich S, Charney D, Lipsky R, Rush AJ, Wilson AF, Sorant AJ, Papanicolaou GJ, Laje G, Fava M, Trivedi MH, Wisniewski SR, Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. American Journal of Human Genetics. 78: 804-14. PMID 16642436 DOI: 10.1086/503820  0.341
2006 Nemeroff CB, Mayberg HS, Krahl SE, McNamara J, Frazer A, Henry TR, George MS, Charney DS, Brannan SK. VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1345-55. PMID 16641939 DOI: 10.1038/Sj.Npp.1301082  0.325
2006 Roberson-Nay R, McClure EB, Monk CS, Nelson EE, Guyer AE, Fromm SJ, Charney DS, Leibenluft E, Blair J, Ernst M, Pine DS. Increased amygdala activity during successful memory encoding in adolescent major depressive disorder: An FMRI study. Biological Psychiatry. 60: 966-73. PMID 16603133 DOI: 10.1016/J.Biopsych.2006.02.018  0.753
2006 Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, Martin L, Gerard E, Charney DS, Peterson BS. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biological Psychiatry. 59: 611-8. PMID 16414030 DOI: 10.1016/J.Biopsych.2005.08.031  0.459
2006 Neumeister A, Drevets WC, Belfer I, Luckenbaugh DA, Henry S, Bonne O, Herscovitch P, Goldman D, Charney DS. Effects of a alpha 2C-adrenoreceptor gene polymorphism on neural responses to facial expressions in depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1750-6. PMID 16407897 DOI: 10.1038/Sj.Npp.1301010  0.347
2006 Zarate CA, Singh JB, Quiroz JA, De Jesus G, Denicoff KK, Luckenbaugh DA, Manji HK, Charney DS. A double-blind, placebo-controlled study of memantine in the treatment of major depression. The American Journal of Psychiatry. 163: 153-5. PMID 16390905 DOI: 10.1176/Appi.Ajp.163.1.153  0.324
2006 Staley JK, Sanacora G, Tamagnan G, Maciejewski PK, Malison RT, Berman RM, Vythilingam M, Kugaya A, Baldwin RM, Seibyl JP, Charney D, Innis RB. Sex differences in diencephalon serotonin transporter availability in major depression. Biological Psychiatry. 59: 40-7. PMID 16139815 DOI: 10.1016/J.Biopsych.2005.06.012  0.573
2006 Vythilingam M, Lawley M, Collin C, Bonne O, Agarwal R, Hadd K, Charney DS, Grillon C. Hydrocortisone impairs hippocampal-dependent trace eyeblink conditioning in post-traumatic stress disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 182-8. PMID 16123770 DOI: 10.1038/Sj.Npp.1300843  0.35
2006 Grillon C, Pine DS, Baas JM, Lawley M, Ellis V, Charney DS. Cortisol and DHEA-S are associated with startle potentiation during aversive conditioning in humans. Psychopharmacology. 186: 434-41. PMID 16052364 DOI: 10.1007/S00213-005-0124-2  0.454
2006 Nemeroff CB, Mayberg HS, Krahl SE, McNamara J, Frazer A, Henry TR, George MS, Charney DS, Brannan SK. Erratum: VNS Therapy in Treatment-Resistant Depression: Clinical Evidence and Putative Neurobiological Mechanisms Neuropsychopharmacology. 31: 2329-2329. DOI: 10.1038/Sj.Npp.1301190  0.308
2006 Cannon DM, Ichise M, Fromm S, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in major depressive disorder and bipolar disorder assessed using [11C]DASB and positron emission tomography Neuroimage. 31. DOI: 10.1016/J.Neuroimage.2006.04.032  0.349
2005 Southwick SM, Vythilingam M, Charney DS. The psychobiology of depression and resilience to stress: implications for prevention and treatment. Annual Review of Clinical Psychology. 1: 255-91. PMID 17716089 DOI: 10.1146/Annurev.Clinpsy.1.102803.143948  0.339
2005 Neumeister A, Daher RJ, Charney DS. Anxiety disorders: noradrenergic neurotransmission Handbook of Experimental Pharmacology. 205-223. PMID 16594260 DOI: 10.1007/3-540-28082-0_8  0.366
2005 Erickson K, Drevets WC, Clark L, Cannon DM, Bain EE, Zarate CA, Charney DS, Sahakian BJ. Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder. The American Journal of Psychiatry. 162: 2171-3. PMID 16263859 DOI: 10.1176/Appi.Ajp.162.11.2171  0.372
2005 Easter J, McClure EB, Monk CS, Dhanani M, Hodgdon H, Leibenluft E, Charney DS, Pine DS, Ernst M. Emotion recognition deficits in pediatric anxiety disorders: implications for amygdala research. Journal of Child and Adolescent Psychopharmacology. 15: 563-70. PMID 16190788 DOI: 10.1089/Cap.2005.15.563  0.654
2005 McClure EB, Treland JE, Snow J, Schmajuk M, Dickstein DP, Towbin KE, Charney DS, Pine DS, Leibenluft E. Deficits in social cognition and response flexibility in pediatric bipolar disorder. The American Journal of Psychiatry. 162: 1644-51. PMID 16135623 DOI: 10.1176/Appi.Ajp.162.9.1644  0.469
2005 Evans DL, Charney DS, Lewis L, Golden RN, Gorman JM, Krishnan KR, Nemeroff CB, Bremner JD, Carney RM, Coyne JC, Delong MR, Frasure-Smith N, Glassman AH, Gold PW, Grant I, et al. Mood disorders in the medically ill: scientific review and recommendations. Biological Psychiatry. 58: 175-89. PMID 16084838 DOI: 10.1016/J.Biopsych.2005.05.001  0.302
2005 Hasler G, Neumeister A, van der Veen JW, Tumonis T, Bain EE, Shen J, Drevets WC, Charney DS. Normal prefrontal gamma-aminobutyric acid levels in remitted depressed subjects determined by proton magnetic resonance spectroscopy. Biological Psychiatry. 58: 969-73. PMID 16043137 DOI: 10.1016/J.Biopsych.2005.05.017  0.374
2005 Dickstein DP, Milham MP, Nugent AC, Drevets WC, Charney DS, Pine DS, Leibenluft E. Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study. Archives of General Psychiatry. 62: 734-41. PMID 15997014 DOI: 10.1001/Archpsyc.62.7.734  0.474
2005 Vythilingam M, Luckenbaugh DA, Lam T, Morgan CA, Lipschitz D, Charney DS, Bremner JD, Southwick SM. Smaller head of the hippocampus in Gulf War-related posttraumatic stress disorder. Psychiatry Research. 139: 89-99. PMID 15967648 DOI: 10.1016/J.Pscychresns.2005.04.003  0.307
2005 Neumeister A, Charney DS, Drevets WC. Hippocampus, VI. Depression and the Hippocampus. The American Journal of Psychiatry. 162: 1057. PMID 15930051 DOI: 10.1176/Appi.Ajp.162.6.1057  0.318
2005 Gold PW, Wong ML, Goldstein DS, Gold HK, Ronsaville DS, Esler M, Alesci S, Masood A, Licinio J, Geracioti TD, Perini G, DeBellis MD, Holmes C, Vgontzas AN, Charney DS, et al. Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia. Proceedings of the National Academy of Sciences of the United States of America. 102: 8303-8. PMID 15919819 DOI: 10.1073/Pnas.0503069102  0.354
2005 Neumeister A, Charney DS, Belfer I, Geraci M, Holmes C, Sharabi Y, Alim T, Bonne O, Luckenbaugh DA, Manji H, Goldman D, Goldstein DS. Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans. Pharmacogenetics and Genomics. 15: 143-9. PMID 15861038 DOI: 10.1097/01213011-200503000-00002  0.316
2005 Milham MP, Nugent AC, Drevets WC, Dickstein DP, Leibenluft E, Ernst M, Charney D, Pine DS. Selective reduction in amygdala volume in pediatric anxiety disorders: a voxel-based morphometry investigation. Biological Psychiatry. 57: 961-6. PMID 15860335 DOI: 10.1016/J.Biopsych.2005.01.038  0.507
2005 McClure EB, Treland JE, Snow J, Dickstein DP, Towbin KE, Charney DS, Pine DS, Leibenluft E. Memory and learning in pediatric bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 44: 461-9. PMID 15843768 DOI: 10.1097/01.Chi.0000156660.30953.91  0.457
2005 Neumeister A, Wood S, Bonne O, Nugent AC, Luckenbaugh DA, Young T, Bain EE, Charney DS, Drevets WC. Reduced hippocampal volume in unmedicated, remitted patients with major depression versus control subjects. Biological Psychiatry. 57: 935-7. PMID 15820716 DOI: 10.1016/J.Biopsych.2005.01.016  0.377
2005 Neumeister A, Yuan P, Young TA, Bonne O, Luckenbaugh DA, Charney DS, Manji H. Effects of tryptophan depletion on serum levels of brain-derived neurotrophic factor in unmedicated patients with remitted depression and healthy subjects. The American Journal of Psychiatry. 162: 805-7. PMID 15800160 DOI: 10.1176/Appi.Ajp.162.4.805  0.386
2005 Zarate CA, Quiroz JA, Singh JB, Denicoff KD, De Jesus G, Luckenbaugh DA, Charney DS, Manji HK. An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biological Psychiatry. 57: 430-2. PMID 15705360 DOI: 10.1016/J.Biopsych.2004.11.023  0.354
2005 Bonne O, Bain E, Neumeister A, Nugent AC, Vythilingam M, Carson RE, Luckenbaugh DA, Eckelman W, Herscovitch P, Drevets WC, Charney DS. No change in serotonin type 1A receptor binding in patients with posttraumatic stress disorder. The American Journal of Psychiatry. 162: 383-5. PMID 15677606 DOI: 10.1176/Appi.Ajp.162.2.383  0.361
2005 Pine DS, Mogg K, Bradley BP, Montgomery L, Monk CS, McClure E, Guyer AE, Ernst M, Charney DS, Kaufman J. Attention bias to threat in maltreated children: implications for vulnerability to stress-related psychopathology. The American Journal of Psychiatry. 162: 291-6. PMID 15677593 DOI: 10.1176/Appi.Ajp.162.2.291  0.731
2005 Cannon DM, Nugent AC, Erickson K, Carson RE, Eckelman WC, Kiesewetter DO, Bain EE, Gandhi SK, Solorio G, Charney D, Drevets WC. Muscarinic cholinergic2 receptor binding in bipolar disorder: Relation to saliency of affective-words Journal of Cerebral Blood Flow & Metabolism. 25: S420-S420. DOI: 10.1038/Sj.Jcbfm.9591524.0420  0.302
2005 Charney DS, Berrettini W, Biederman J, Innis RB, Nestler EJ, Rush AJ. Maintaining a Steady Course Biological Psychiatry. 58: 433-434. DOI: 10.1016/J.Biopsych.2005.09.001  0.38
2004 Bonne O, Charney DS. Neuropathology of stress: Prospects and caveats Psychiatry. 67: 407-411. PMID 15801382 DOI: 10.1521/Psyc.67.4.407.56561  0.32
2004 Bremner JD, Vythilingam M, Vermetten E, Afzal N, Nazeer A, Newcomer JW, Charney DS. Effects of dexamethasone on declarative memory function in posttraumatic stress disorder. Psychiatry Research. 129: 1-10. PMID 15572179 DOI: 10.1016/J.Psychres.2004.08.004  0.301
2004 Weiland-Fiedler P, Erickson K, Waldeck T, Luckenbaugh DA, Pike D, Bonne O, Charney DS, Neumeister A. Evidence for continuing neuropsychological impairments in depression. Journal of Affective Disorders. 82: 253-8. PMID 15488254 DOI: 10.1016/J.Jad.2003.10.009  0.361
2004 Monk CS, Nelson EE, Woldehawariat G, Montgomery LA, Zarahn E, McClure EB, Guyer AE, Leibenluft E, Charney DS, Ernst M, Pine DS. Experience-dependent plasticity for attention to threat: Behavioral and neurophysiological evidence in humans. Biological Psychiatry. 56: 607-10. PMID 15476691 DOI: 10.1016/J.Biopsych.2004.07.012  0.743
2004 Kugaya A, Sanacora G, Staley JK, Malison RT, Bozkurt A, Khan S, Anand A, Van Dyck CH, Baldwin RM, Seibyl JP, Charney D, Innis RB. Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors. Biological Psychiatry. 56: 497-502. PMID 15450785 DOI: 10.1016/J.Biopsych.2004.07.001  0.58
2004 Ernst M, Nelson EE, McClure EB, Monk CS, Munson S, Eshel N, Zarahn E, Leibenluft E, Zametkin A, Towbin K, Blair J, Charney D, Pine DS. Choice selection and reward anticipation: an fMRI study. Neuropsychologia. 42: 1585-97. PMID 15327927 DOI: 10.1016/J.Neuropsychologia.2004.05.011  0.61
2004 Morgan CA, Southwick S, Hazlett G, Rasmusson A, Hoyt G, Zimolo Z, Charney D. Relationships among plasma dehydroepiandrosterone sulfate and cortisol levels, symptoms of dissociation, and objective performance in humans exposed to acute stress. Archives of General Psychiatry. 61: 819-825. PMID 15289280 DOI: 10.1001/Archpsyc.61.8.819  0.307
2004 Neumeister A, Nugent AC, Waldeck T, Geraci M, Schwarz M, Bonne O, Bain EE, Luckenbaugh DA, Herscovitch P, Charney DS, Drevets WC. Neural and behavioral responses to tryptophan depletion in unmedicated patients with remitted major depressive disorder and controls. Archives of General Psychiatry. 61: 765-73. PMID 15289275 DOI: 10.1001/Archpsyc.61.8.765  0.4
2004 Blumberg HP, Kaufman J, Martin A, Charney DS, Krystal JH, Peterson BS. Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder. Annals of the New York Academy of Sciences. 1021: 376-83. PMID 15251913 DOI: 10.1196/Annals.1308.048  0.46
2004 Vythilingam M, Vermetten E, Anderson GM, Luckenbaugh D, Anderson ER, Snow J, Staib LH, Charney DS, Bremner JD. Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment. Biological Psychiatry. 56: 101-12. PMID 15231442 DOI: 10.1016/J.Biopsych.2004.04.002  0.369
2004 Zarate CA, Payne JL, Singh J, Quiroz JA, Luckenbaugh DA, Denicoff KD, Charney DS, Manji HK. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biological Psychiatry. 56: 54-60. PMID 15219473 DOI: 10.1016/J.Biopsych.2004.03.013  0.386
2004 Hasler G, Drevets WC, Manji HK, Charney DS. Discovering endophenotypes for major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1765-81. PMID 15213704 DOI: 10.1038/Sj.Npp.1300506  0.349
2004 Rasmusson AM, Vasek J, Lipschitz DS, Vojvoda D, Mustone ME, Shi Q, Gudmundsen G, Morgan CA, Wolfe J, Charney DS. An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1546-57. PMID 15199367 DOI: 10.1038/Sj.Npp.1300432  0.332
2004 McClure EB, Monk CS, Nelson EE, Zarahn E, Leibenluft E, Bilder RM, Charney DS, Ernst M, Pine DS. A developmental examination of gender differences in brain engagement during evaluation of threat. Biological Psychiatry. 55: 1047-55. PMID 15158422 DOI: 10.1016/J.Biopsych.2004.02.013  0.625
2004 Bremner JD, Vythilingam M, Vermetten E, Vaccarino V, Charney DS. Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. The American Journal of Psychiatry. 161: 637-45. PMID 15056509 DOI: 10.1176/Appi.Ajp.161.4.637  0.315
2004 Bremner JD, Vythilingam M, Vermetten E, Anderson G, Newcomer JW, Charney DS. Effects of glucocorticoids on declarative memory function in major depression. Biological Psychiatry. 55: 811-5. PMID 15050862 DOI: 10.1016/J.Biopsych.2003.10.020  0.364
2004 Charney DS, Manji HK. Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention Science's Stke : Signal Transduction Knowledge Environment. 2004. PMID 15039492 DOI: 10.1126/Stke.2252004Re5  0.355
2004 Bonne O, Grillon C, Vythilingam M, Neumeister A, Charney DS. Adaptive and maladaptive psychobiological responses to severe psychological stress: Implications for the discovery of novel pharmacotherapy Neuroscience and Biobehavioral Reviews. 28: 65-94. PMID 15036934 DOI: 10.1016/J.Neubiorev.2003.12.001  0.317
2004 Bremner JD, Vermetten E, Vythilingam M, Afzal N, Schmahl C, Elzinga B, Charney DS. Neural correlates of the classic color and emotional stroop in women with abuse-related posttraumatic stress disorder. Biological Psychiatry. 55: 612-20. PMID 15013830 DOI: 10.1016/J.Biopsych.2003.10.001  0.31
2004 Sanacora G, Berman RM, Cappiello A, Oren DA, Kugaya A, Liu N, Gueorguieva R, Fasula D, Charney DS. Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1166-71. PMID 15010697 DOI: 10.1038/Sj.Npp.1300418  0.557
2004 Perry EB, Berman RM, Sanacora G, Anand A, Lynch-Colonese K, Charney DS. Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial. The Journal of Clinical Psychiatry. 65: 238-43. PMID 15003079 DOI: 10.4088/Jcp.V65N0215  0.598
2004 Zarate CA, Payne JL, Quiroz J, Sporn J, Denicoff KK, Luckenbaugh D, Charney DS, Manji HK. An open-label trial of riluzole in patients with treatment-resistant major depression. The American Journal of Psychiatry. 161: 171-4. PMID 14702270 DOI: 10.1176/Appi.Ajp.161.1.171  0.367
2004 McEwen BS, Charney D. Worldview of Psychiatry: Neurodegeneration in Stress and Anxiety Disorders: Mechanisms and Implications The Journal of Clinical Psychiatry. 65: 281-282. DOI: 10.4088/Jcp.V65N0222  0.336
2004 LEIBENLUFT E, CHARNEY DS, TOWBIN KE, BHANGOO RK, PINE DS. Dr. Leibenluft and Colleagues Reply American Journal of Psychiatry. 161: 764-a-764. DOI: 10.1176/Appi.Ajp.161.4.764-A  0.367
2003 Monk CS, Grillon C, Baas JM, McClure EB, Nelson EE, Zarahn E, Charney DS, Ernst M, Pine DS. A neuroimaging method for the study of threat in adolescents. Developmental Psychobiology. 43: 359-66. PMID 15027419 DOI: 10.1002/Dev.10146  0.638
2003 Leibenluft E, Blair RJ, Charney DS, Pine DS. Irritability in pediatric mania and other childhood psychopathology. Annals of the New York Academy of Sciences. 1008: 201-18. PMID 14998886 DOI: 10.1196/Annals.1301.022  0.481
2003 Zarate CA, Du J, Quiroz J, Gray NA, Denicoff KD, Singh J, Charney DS, Manji HK. Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system. Annals of the New York Academy of Sciences. 1003: 273-91. PMID 14684452 DOI: 10.1196/Annals.1300.017  0.357
2003 Blumberg HP, Kaufman J, Martin A, Whiteman R, Zhang JH, Gore JC, Charney DS, Krystal JH, Peterson BS. Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder. Archives of General Psychiatry. 60: 1201-8. PMID 14662552 DOI: 10.1001/Archpsyc.60.12.1201  0.476
2003 Coyle JT, Pine DS, Charney DS, Lewis L, Nemeroff CB, Carlson GA, Joshi PT, Reiss D, Todd RD, Hellander M. Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 1494-503. PMID 14627885 DOI: 10.1097/00004583-200312000-00017  0.475
2003 Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB. Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. Biological Psychiatry. 54: 792-9. PMID 14550678 DOI: 10.1016/S0006-3223(02)01788-2  0.565
2003 Monk CS, McClure EB, Nelson EE, Zarahn E, Bilder RM, Leibenluft E, Charney DS, Ernst M, Pine DS. Adolescent immaturity in attention-related brain engagement to emotional facial expressions. Neuroimage. 20: 420-8. PMID 14527602 DOI: 10.1016/S1053-8119(03)00355-0  0.622
2003 Vermetten E, Vythilingam M, Southwick SM, Charney DS, Bremner JD. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biological Psychiatry. 54: 693-702. PMID 14512209 DOI: 10.1016/S0006-3223(03)00634-6  0.306
2003 Krystal JH, Petrakis IL, Limoncelli D, Webb E, Gueorgueva R, D'Souza DC, Boutros NN, Trevisan L, Charney DS. Altered NMDA glutamate receptor antagonist response in recovering ethanol-dependent patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2020-8. PMID 12888778 DOI: 10.1038/Sj.Npp.1300252  0.431
2003 Charney DS, Reynolds CF, Lewis L, Lebowitz BD, Sunderland T, Alexopoulos GS, Blazer DG, Katz IR, Meyers BS, Arean PA, Borson S, Brown C, Bruce ML, Callahan CM, Charlson ME, et al. Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Archives of General Psychiatry. 60: 664-72. PMID 12860770 DOI: 10.1001/Archpsyc.60.7.664  0.344
2003 Blumberg HP, Martin A, Kaufman J, Leung HC, Skudlarski P, Lacadie C, Fulbright RK, Gore JC, Charney DS, Krystal JH, Peterson BS. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. The American Journal of Psychiatry. 160: 1345-7. PMID 12832254 DOI: 10.1176/Appi.Ajp.160.7.1345  0.502
2003 Insel TR, Charney DS. Research on major depression: strategies and priorities. Jama. 289: 3167-8. PMID 12813123 DOI: 10.1001/Jama.289.23.3167  0.394
2003 Bremner JD, Vythilingam M, Ng CK, Vermetten E, Nazeer A, Oren DA, Berman RM, Charney DS. Regional brain metabolic correlates of alpha-methylparatyrosine-induced depressive symptoms: implications for the neural circuitry of depression. Jama. 289: 3125-34. PMID 12813118 DOI: 10.1001/Jama.289.23.3125  0.359
2003 Bremner JD, Vythilingam M, Vermetten E, Adil J, Khan S, Nazeer A, Afzal N, McGlashan T, Elzinga B, Anderson GM, Heninger G, Southwick SM, Charney DS. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology. 28: 733-50. PMID 12812861 DOI: 10.1016/S0306-4530(02)00067-7  0.32
2003 Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices. Archives of General Psychiatry. 60: 601-9. PMID 12796223 DOI: 10.1001/Archpsyc.60.6.601  0.499
2003 Leibenluft E, Charney DS, Pine DS. Researching the pathophysiology of pediatric bipolar disorder Biological Psychiatry. 53: 1009-1020. PMID 12788246 DOI: 10.1016/S0006-3223(03)00069-6  0.49
2003 Manji HK, Quiroz JA, Sporn J, Payne JL, Denicoff K, A Gray N, Zarate CA, Charney DS. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biological Psychiatry. 53: 707-42. PMID 12706957 DOI: 10.1016/S0006-3223(03)00117-3  0.362
2003 Kupfer DJ, Charney DS. Difficult-to-treat depression Biological Psychiatry. 53: 633-634. PMID 12706948 DOI: 10.1016/S0006-3223(03)00188-4  0.328
2003 Southwick SM, Axelrod SR, Wang S, Yehuda R, Morgan CA, Charney D, Rosenheck R, Mason JW. Twenty-four-hour urine cortisol in combat veterans with PTSD and comorbid borderline personality disorder. The Journal of Nervous and Mental Disease. 191: 261-2. PMID 12695738 DOI: 10.1097/01.Nmd.0000061140.93952.28  0.355
2003 Leibenluft E, Charney DS, Towbin KE, Bhangoo RK, Pine DS. Defining clinical phenotypes of juvenile mania. The American Journal of Psychiatry. 160: 430-7. PMID 12611821 DOI: 10.1176/Appi.Ajp.160.3.430  0.449
2003 Charney DS. Neuroanatomical circuits modulating fear and anxiety behaviors Acta Psychiatrica Scandinavica, Supplement. 108: 38-50. DOI: 10.1034/J.1600-0447.108.S417.3.X  0.385
2003 Rasmusson A, Guidotti A, Charney D, Vojvoda D, Lipschitz D, Weisman D, Krystal J. S.20.01 Adrenal & CSF neurosteroids as mediators of HPA axis upregulation and symptom production in premenopausal women with PTSD European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)91680-4  0.422
2003 Charney DS, Innis RB, Nestler EJ. New initiatives in Biological Psychiatry Biological Psychiatry. 53: 1-2. DOI: 10.1016/S0006-3223(02)01858-9  0.385
2002 Vythilingam M, Heim C, Newport J, Miller AH, Anderson E, Bronen R, Brummer M, Staib L, Vermetten E, Charney DS, Nemeroff CB, Bremner JD. Childhood trauma associated with smaller hippocampal volume in women with major depression. The American Journal of Psychiatry. 159: 2072-80. PMID 12450959 DOI: 10.1176/Appi.Ajp.159.12.2072  0.374
2002 Blumberg HP, Charney DS, Krystal JH. Frontotemporal neural systems in bipolar disorder. Seminars in Clinical Neuropsychiatry. 7: 243-54. PMID 12382207 DOI: 10.1053/Scnp.2002.35220  0.512
2002 Blumberg HP, Charney DS. The neuroanatomy of mood disorders. Introduction Seminars in Clinical Neuropsychiatry. 7: 221-222. PMID 12382204 DOI: 10.1053/Scnp.2002.35312  0.325
2002 Pine DS, Charney DS. Children, stress, and sensitization: An integration of basic and clinical research on emotion? Biological Psychiatry. 52: 773-775. PMID 12372648 DOI: 10.1016/S0006-3223(02)01569-X  0.402
2002 Gold PW, Drevets WC, Charney DS. New insights into the role of cortisol and the glucocorticoid receptor in severe depression Biological Psychiatry. 52: 381-385. PMID 12242053 DOI: 10.1016/S0006-3223(02)01480-4  0.333
2002 Lappalainen J, Kranzler HR, Malison R, Price LH, Van Dyck C, Rosenheck RA, Cramer J, Southwick S, Charney D, Krystal J, Gelernter J. A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States. Archives of General Psychiatry. 59: 825-31. PMID 12215082 DOI: 10.1001/Archpsyc.59.9.825  0.537
2002 Abi-Saab W, Seibyl JP, D'Souza DC, Karper LP, Gueorgueva R, Abi-Dargham A, Wong ML, Rajhans S, Erdos JP, Heninger GR, Charney DS, Krystal JH. Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms. Psychopharmacology. 162: 55-62. PMID 12107618 DOI: 10.1007/S00213-002-1057-7  0.477
2002 Krystal JH, Sanacora G, Blumberg H, Anand A, Charney DS, Marek G, Epperson CN, Goddard A, Mason GF. Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Molecular Psychiatry. 7: S71-80. PMID 11986998 DOI: 10.1038/Sj.Mp.4001021  0.635
2002 Bremner JD, Vythilingam M, Vermetten E, Nazeer A, Adil J, Khan S, Staib LH, Charney DS. Reduced volume of orbitofrontal cortex in major depression. Biological Psychiatry. 51: 273-9. PMID 11958777 DOI: 10.1016/S0006-3223(01)01336-1  0.35
2002 Stine SM, Southwick SM, Petrakis IL, Kosten TR, Charney DS, Krystal JH. Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients. Biological Psychiatry. 51: 642-51. PMID 11955464 DOI: 10.1016/S0006-3223(01)01292-6  0.453
2002 Monk CS, Pine DS, Charney DS. A developmental and neurobiological approach to early trauma research. Seminars in Clinical Neuropsychiatry. 7: 137-46. PMID 11953938 DOI: 10.1053/Scnp.2002.31793  0.631
2002 Berman RM, Sanacora G, Anand A, Roach LM, Fasula MK, Finkelstein CO, Wachen RM, Oren DA, Heninger GR, Charney DS. Monoamine depletion in unmedicated depressed subjects. Biological Psychiatry. 51: 469-73. PMID 11922881 DOI: 10.1016/S0006-3223(01)01285-9  0.599
2002 Mason JW, Wang S, Yehuda R, Lubin H, Johnson D, Bremner JD, Charney D, Southwick S. Marked lability in urinary cortisol levels in subgroups of combat veterans with posttraumatic stress disorder during an intensive exposure treatment program. Psychosomatic Medicine. 64: 238-46. PMID 11914439 DOI: 10.1097/00006842-200203000-00006  0.336
2002 Oren DA, Desan PH, Boutros N, Anand A, Charney DS. Effects of light on low nocturnal bilirubin in winter depression: A preliminary report Biological Psychiatry. 51: 422-425. PMID 11904137 DOI: 10.1016/S0006-3223(01)01254-9  0.35
2002 Charney DS, Nemeroff CB, Lewis L, Laden SK, Gorman JM, Laska EM, Borenstein M, Bowden CL, Caplan A, Emslie GJ, Evans DL, Geller B, Grabowski LE, Herson J, Kalin NH, et al. National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders. Archives of General Psychiatry. 59: 262-70. PMID 11879164 DOI: 10.1001/Archpsyc.59.3.262  0.41
2002 Reynolds CF, Charney DS. Unmet needs in the diagnosis and treatment of mood disorders in later life Biological Psychiatry. 52: 145-147. DOI: 10.1016/S0006-3223(02)01464-6  0.31
2001 Goddard AW, Brouette T, Almai A, Jetty P, Woods SW, Charney D. Early coadministration of clonazepam with sertraline for panic disorder Archives of General Psychiatry. 58: 681-686. PMID 11448376 DOI: 10.1001/Archpsyc.58.7.681  0.356
2001 Kaufman J, Martin A, King RA, Charney D. Are child-, adolescent-, and adult-onset depression one and the same disorder? Biological Psychiatry. 49: 980-1001. PMID 11430841 DOI: 10.1016/S0006-3223(01)01127-1  0.37
2001 Goddard AW, Mason GF, Almai A, Rothman DL, Behar KL, Petroff OA, Charney DS, Krystal JH. Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Archives of General Psychiatry. 58: 556-61. PMID 11386984 DOI: 10.1001/Archpsyc.58.6.556  0.452
2001 Morgan CA, Wang S, Rasmusson A, Hazlett G, Anderson G, Charney DS. Relationship among plasma cortisol, catecholamines, neuropeptide Y, and human performance during exposure to uncontrollable stress. Psychosomatic Medicine. 63: 412-22. PMID 11382268 DOI: 10.1097/00006842-200105000-00010  0.306
2001 Mason JW, Wang S, Yehuda R, Riney S, Charney DS, Southwick SM. Psychogenic lowering of urinary cortisol levels linked to increased emotional numbing and a shame-depressive syndrome in combat-related posttraumatic stress disorder. Psychosomatic Medicine. 63: 387-401. PMID 11382266 DOI: 10.1097/00006842-200105000-00008  0.391
2001 Stine SM, Grillon CG, Morgan CA, Kosten TR, Charney DS, Krystal JH. Methadone patients exhibit increased startle and cortisol response after intravenous yohimbine. Psychopharmacology. 154: 274-81. PMID 11351934 DOI: 10.1007/S002130000644  0.494
2001 Krystal JH, D'Souza DC, Sanacora G, Goddard AW, Charney DS. Current perspectives on the pathophysiology of schizophrenia, depression, and anxiety disorders. The Medical Clinics of North America. 85: 559-77. PMID 11349473 DOI: 10.1016/S0025-7125(05)70329-1  0.658
2001 Manji HK, Drevets WC, Charney DS. The cellular neurobiology of depression Nature Medicine. 7: 541-547. PMID 11329053 DOI: 10.1038/87865  0.34
2001 Jetty PV, Charney DS, Goddard AW. Neurobiology of generalized anxiety disorder Psychiatric Clinics of North America. 24: 75-97. PMID 11225510 DOI: 10.1016/S0193-953X(05)70207-0  0.391
2001 Shelton RC, Charney DS, Trivedi M. Do Dual-Action Neurotransmitter Agents Offer an Advantage in Psychiatric Treatment? Cns Spectrums. 6: 1-8. DOI: 10.1017/S109285290000153X  0.359
2001 Kaufman J, Charney D. Effects of early stress on brain structure and function: Implications for understanding the relationship between child maltreatment and depression Development and Psychopathology. 13: 451-471. DOI: 10.1017/S0954579401003030  0.323
2000 Fujita M, Charney DS, Innis RB. Imaging serotonergic neurotransmission in depression: Hippocampal pathophysiology may mirror global brain alterations Biological Psychiatry. 48: 801-812. PMID 11063976 DOI: 10.1016/S0006-3223(00)00960-4  0.345
2000 Kaufman J, Plotsky PM, Nemeroff CB, Charney DS. Effects of early adverse experiences on brain structure and function: clinical implications. Biological Psychiatry. 48: 778-90. PMID 11063974 DOI: 10.1016/S0006-3223(00)00998-7  0.369
2000 Charney DS. Bipolar disorder: Can studies of natural history help us define clinically and neurobiologically relevant subtypes? Biological Psychiatry. 48: 427. PMID 11018212 DOI: 10.1016/S0006-3223(00)00992-6  0.32
2000 Vythilingam M, Anderson ER, Goddard A, Woods SW, Staib LH, Charney DS, Bremner JD. Temporal lobe volume in panic disorder--a quantitative magnetic resonance imaging study. Psychiatry Research. 99: 75-82. PMID 10963983 DOI: 10.1016/S0925-4927(00)00055-X  0.333
2000 Desan PH, Oren DA, Malison R, Price LH, Rosenbaum J, Smoller J, Charney DS, Gelernter J. Genetic polymorphism at the CLOCK gene locus and major depression American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 418-421. PMID 10898925 DOI: 10.1002/1096-8628(20000612)96:3<418::Aid-Ajmg34>3.0.Co;2-S  0.506
2000 Oren DA, Berman RM, Anand A, Charney DS. No effect of light on basal glucagon levels in winter seasonal depressives and comparison subjects. Psychiatry Research. 94: 263-6. PMID 10889291 DOI: 10.1016/S0165-1781(00)00158-X  0.345
2000 Bremner JD, Innis RB, Southwick SM, Staib L, Zoghbi S, Charney DS. Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder. The American Journal of Psychiatry. 157: 1120-6. PMID 10873921 DOI: 10.1176/Appi.Ajp.157.7.1120  0.313
2000 Anand A, Verhoeff P, Seneca N, Zoghbi SS, Seibyl JP, Charney DS, Innis RB. Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients. The American Journal of Psychiatry. 157: 1108-14. PMID 10873919 DOI: 10.1176/Appi.Ajp.157.7.1108  0.318
2000 Hoffman RE, Boutros NN, Hu S, Berman RM, Krystal JH, Charney DS. Transcranial magnetic stimulation and auditory hallucinations in schizophrenia. Lancet. 355: 1073-5. PMID 10744097 DOI: 10.1016/S0140-6736(00)02043-2  0.407
2000 Rasmusson AM, Hauger RL, Morgan CA, Bremner JD, Charney DS, Southwick SM. Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD. Biological Psychiatry. 47: 526-39. PMID 10715359 DOI: 10.1016/S0006-3223(99)00185-7  0.329
2000 Anand A, Charney DS, Oren DA, Berman RM, Hu XS, Cappiello A, Krystal JH. Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists. Archives of General Psychiatry. 57: 270-6. PMID 10711913 DOI: 10.1001/Archpsyc.57.3.270  0.436
2000 D'Souza DC, Gil R, Cassello K, Morrissey K, Abi-Saab D, White J, Sturwold R, Bennett A, Karper LP, Zuzarte E, Charney DS, Krystal JH. IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans. Biological Psychiatry. 47: 450-62. PMID 10704956 DOI: 10.1016/S0006-3223(99)00133-X  0.441
2000 Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS, Krystal JH. Antidepressant effects of ketamine in depressed patients. Biological Psychiatry. 47: 351-4. PMID 10686270 DOI: 10.1016/S0006-3223(99)00230-9  0.51
2000 Berman RM, Narasimhan M, Sanacora G, Miano AP, Hoffman RE, Hu XS, Charney DS, Boutros NN. A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression. Biological Psychiatry. 47: 332-7. PMID 10686268 DOI: 10.1016/S0006-3223(99)00243-7  0.592
2000 Rosenheck R, Evans D, Herz L, Cramer J, Xu W, Thomas J, Henderson W, Charney D. How long to wait for a response to clozapine: a comparison of time course of response to clozapine and conventional antipsychotic medication in refractory schizophrenia. Schizophrenia Bulletin. 25: 709-19. PMID 10667741 DOI: 10.1093/Oxfordjournals.Schbul.A033412  0.308
2000 Krystal JH, Bennett A, Abi-Saab D, Belger A, Karper LP, D'Souza DC, Lipschitz D, Abi-Dargham A, Charney DS. Dissociation of ketamine effects on rule acquisition and rule implementation: possible relevance to NMDA receptor contributions to executive cognitive functions. Biological Psychiatry. 47: 137-43. PMID 10664830 DOI: 10.1016/S0006-3223(99)00097-9  0.453
2000 Bremner JD, Innis RB, White T, Fujita M, Silbersweig D, Goddard AW, Staib L, Stern E, Cappiello A, Woods S, Baldwin R, Charney DS. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry. 47: 96-106. PMID 10664825 DOI: 10.1016/S0006-3223(99)00188-2  0.349
2000 Bremner JD, Narayan M, Anderson ER, Staib LH, Miller HL, Charney DS. Hippocampal volume reduction in major depression. The American Journal of Psychiatry. 157: 115-8. PMID 10618023 DOI: 10.1176/Ajp.157.1.115  0.339
2000 Rosenheck R, Chang S, Choe Y, Cramer J, Xu W, Thomas J, Henderson W, Charney D. Medication Continuation and Compliance The Journal of Clinical Psychiatry. 61: 382-386. DOI: 10.4088/Jcp.V61N0511  0.317
2000 Martin A, Kaufman J, Charney D. Pharmacotherapy of Early-Onset Depression. Update and New Directions Child and Adolescent Psychiatric Clinics of North America. 9: 135-157. DOI: 10.1016/S1056-4993(18)30139-1  0.315
2000 Anand A, Berman R, Charney D, Krystal J. Attenuation of ketamine effects in healthy humans by lamotrigine, a drug that reduces glutamate release Schizophrenia Research. 41: 33. DOI: 10.1016/S0920-9964(00)90372-4  0.318
2000 Hoffman R, Boutros N, Berman R, Hu S, Rachid F, Schaffer N, Krystal J, Charney D. 401. One Hertz rTMS of left temporoparietal cortex in schizophrenic patients reporting auditory hallucinations Biological Psychiatry. 47: S122-S123. DOI: 10.1016/S0006-3223(00)00670-3  0.328
2000 Berman R, Sanacora G, Narasimhan M, Oren D, Cappiello A, Charney D. 268. Simultaneous catecholamine and indoleamine depletion in unmedicated depressed subjects Biological Psychiatry. 47: S81. DOI: 10.1016/S0006-3223(00)00532-1  0.52
1999 Verhoeff NP, Soares JC, D'Souza CD, Gil R, Degen K, Abi-Dargham A, Zoghbi SS, Fujita M, Rajeevan N, Seibyl JP, Krystal JH, van Dyck CH, Charney DS, Innis RB. [123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia. Psychiatry Research. 91: 163-73. PMID 10641580 DOI: 10.1016/S0925-4927(99)00027-X  0.462
1999 Sanacora G, Mason GF, Rothman DL, Behar KL, Hyder F, Petroff OA, Berman RM, Charney DS, Krystal JH. Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Archives of General Psychiatry. 56: 1043-7. PMID 10565505 DOI: 10.1001/Archpsyc.56.11.1043  0.618
1999 Southwick SM, Bremner JD, Rasmusson A, Morgan CA, Arnsten A, Charney DS. Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder. Biological Psychiatry. 46: 1192-204. PMID 10560025 DOI: 10.1016/S0006-3223(99)00219-X  0.319
1999 Chambers RA, Bremner JD, Moghaddam B, Southwick SM, Charney DS, Krystal JH. Glutamate and post-traumatic stress disorder: toward a psychobiology of dissociation. Seminars in Clinical Neuropsychiatry. 4: 274-81. PMID 10553033 DOI: 10.153/SCNP00400274  0.373
1999 Southwick SM, Paige S, Morgan CA, Bremner JD, Krystal JH, Charney DS. Neurotransmitter alterations in PTSD: catecholamines and serotonin. Seminars in Clinical Neuropsychiatry. 4: 242-8. PMID 10553029 DOI: 10.153/SCNP00400242  0.452
1999 D'Souza DC, Berman RM, Krystal JH, Charney DS. Symptom provocation studies in psychiatric disorders: scientific value, risks, and future. Biological Psychiatry. 46: 1060-80. PMID 10536743 DOI: 10.1016/S0006-3223(99)00209-7  0.471
1999 Krystal JH, D'Souza DC, Petrakis IL, Belger A, Berman RM, Charney DS, Abi-Saab W, Madonick S. NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders. Harvard Review of Psychiatry. 7: 125-43. PMID 10483932 DOI: 10.3109/Hrp.7.3.125  0.477
1999 Krystal JH, D'Souza DC, Karper LP, Bennett A, Abi-Dargham A, Abi-Saab D, Cassello K, Bowers MB, Vegso S, Heninger GR, Charney DS. Interactive effects of subanesthetic ketamine and haloperidol in healthy humans. Psychopharmacology. 145: 193-204. PMID 10463321 DOI: 10.1007/S002130051049  0.468
1999 Southwick SM, Morgan CA, Charney DS, High JR. Yohimbine use in a natural setting: Effects on posttraumatic stress disorder Biological Psychiatry. 46: 442-444. PMID 10435213 DOI: 10.1016/S0006-3223(99)00107-9  0.353
1999 Delgado PL, Miller HL, Salomon RM, Licinio J, Krystal JH, Moreno FA, Heninger GR, Charney DS. Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action. Biological Psychiatry. 46: 212-20. PMID 10418696 DOI: 10.1016/S0006-3223(99)00014-1  0.492
1999 Hoffman RE, Boutros NN, Berman RM, Roessler E, Belger A, Krystal JH, Charney DS. Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated "voices". Biological Psychiatry. 46: 130-2. PMID 10394483 DOI: 10.1016/S0006-3223(98)00358-8  0.421
1999 Charney DS, Innis RB, Nestler EJ, Davis KL, Nemeroff CB, Weinberger DR. Increasing public trust and confidence in psychiatric research. Biological Psychiatry. 46: 1-2. PMID 10394467 DOI: 10.1016/S0006-3223(99)00096-7  0.418
1999 Anand A, Darnell A, Miller HL, Berman RM, Cappiello A, Oren DA, Woods SW, Charney DS. Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder. Biological Psychiatry. 45: 972-8. PMID 10386179 DOI: 10.1016/S0006-3223(98)00293-5  0.318
1999 Behar KL, Rothman DL, Petersen KF, Hooten M, Delaney R, Petroff OA, Shulman GI, Navarro V, Petrakis IL, Charney DS, Krystal JH. Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. The American Journal of Psychiatry. 156: 952-4. PMID 10360140 DOI: 10.1176/Ajp.156.6.952  0.427
1999 Goddard AW, Woods SW, Money R, Pande AC, Charney DS, Goodman WK, Heninger GR, Price LH. Effects of the CCK(B) antagonist CI-988 on responses to mCPP in generalized anxiety disorder Psychiatry Research. 85: 225-240. PMID 10333376 DOI: 10.1016/S0165-1781(99)00015-3  0.513
1999 Berman RM, Anand A, Cappiello A, Miller HL, Hu XS, Oren DA, Charney DS. The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial. Biological Psychiatry. 45: 1170-7. PMID 10331109 DOI: 10.1016/S0006-3223(98)00383-7  0.347
1999 Abi-Dargham A, Laruelle M, Krystal J, D'Souza C, Zoghbi S, Baldwin RM, Seibyl J, Mawlawi O, de Erasquin G, Charney D, Innis RB. No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 650-61. PMID 10327433 DOI: 10.1016/S0893-133X(98)00107-9  0.459
1999 Berman RM, Narasimhan M, Miller HL, Anand A, Cappiello A, Oren DA, Heninger GR, Charney DS. Transient depressive relapse induced by catecholamine depletion: potential phenotypic vulnerability marker? Archives of General Psychiatry. 56: 395-403. PMID 10232292 DOI: 10.1001/Archpsyc.56.5.395  0.351
1999 Bremner JD, Staib LH, Kaloupek D, Southwick SM, Soufer R, Charney DS. Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study. Biological Psychiatry. 45: 806-16. PMID 10202567 DOI: 10.1016/S0006-3223(98)00297-2  0.316
1999 Fujita M, Woods SW, Verhoeff NP, Abi-Dargham A, Baldwin RM, Zoghbi SS, Soares JC, Jatlow PA, Krystal JH, Rajeevan N, Charney DS, Seibyl JP, Innis RB. Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans. European Journal of Pharmacology. 368: 161-72. PMID 10193652 DOI: 10.1016/S0014-2999(99)00013-8  0.436
1999 Gelernter J, Southwick S, Goodson S, Morgan A, Nagy L, Charney DS. No association between D2 dopamine receptor (DRD2) "A" system alleles, or DRD2 haplotypes, and posttraumatic stress disorder. Biological Psychiatry. 45: 620-5. PMID 10088049 DOI: 10.1016/S0006-3223(98)00087-0  0.328
1999 Johnson DR, Lubin H, Rosenheck R, Fontana A, Charney D, Southwick S. Comparison of outcome between homogeneous and heterogeneous treatment environments in combat-related posttraumatic stress disorder. The Journal of Nervous and Mental Disease. 187: 88-95. PMID 10067948 DOI: 10.1097/00005053-199902000-00004  0.328
1999 Cappiello A, McDougle CJ, Delgado PL, Malison RT, Jatlow P, Charney DS, Heninger GR, Price LH. Lithium and desipramine versus desipramine alone in the treatment of severe major depression: a preliminary study. International Clinical Psychopharmacology. 13: 191-8. PMID 9817623 DOI: 10.1097/00004850-199809000-00001  0.561
1999 Sanacora G, Mason GF, Rothman DL, Berman RM, Charney DS, Ciarcia JJ, Krystal JH. 1. ECT Effects on Cortical GABA Levels as Determined by 1H-MRS The Journal of Ect. 15: 102. DOI: 10.1097/00124509-199903000-00009  0.57
1999 Krystal JH, Belger A, D'Souza DC, Anand A, Charney DS, Aghajanian GK, Moghaddam B. Therapeutic implications of the hyperglutamatergic effects of NMDA antagonists Neuropsychopharmacology. 21: S143-S157. DOI: 10.1016/S0893-133X(99)00102-5  0.445
1998 Malison RT, Price LH, Berman R, van Dyck CH, Pelton GH, Carpenter L, Sanacora G, Owens MJ, Nemeroff CB, Rajeevan N, Baldwin RM, Seibyl JP, Innis RB, Charney DS. Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography. Biological Psychiatry. 44: 1090-8. PMID 9836013 DOI: 10.1016/S0006-3223(98)00272-8  0.66
1998 Abi-Dargham A, Krystal JH, Anjilvel S, Scanley BE, Zoghbi S, Baldwin RM, Rajeevan N, Ellis S, Petrakis IL, Seibyl JP, Charney DS, Laruelle M, Innis RB. Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil. The American Journal of Psychiatry. 155: 1550-5. PMID 9812116 DOI: 10.1176/Ajp.155.11.1550  0.415
1998 Abi-Dargham A, Gil R, Krystal J, Baldwin RM, Seibyl JP, Bowers M, van Dyck CH, Charney DS, Innis RB, Laruelle M. Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort. The American Journal of Psychiatry. 155: 761-7. PMID 9619147 DOI: 10.1176/Ajp.155.6.761  0.439
1998 Sernyak MJ, Glazer WM, Heninger GR, Charney DS, Woods SW, Petrakis IL, Krystal JH, Price LH. Naltrexone augmentation of neuroleptics in schizophrenia. Journal of Clinical Psychopharmacology. 18: 248-51. PMID 9617985 DOI: 10.1097/00004714-199806000-00011  0.606
1998 Krystal JH, Petrakis IL, Webb E, Cooney NL, Karper LP, Namanworth S, Stetson P, Trevisan LA, Charney DS. Dose-related ethanol-like effects of the NMDA antagonist, ketamine, in recently detoxified alcoholics. Archives of General Psychiatry. 55: 354-60. PMID 9554431 DOI: 10.1001/Archpsyc.55.4.354  0.411
1998 Krystal JH, Karper LP, Bennett A, D'Souza DC, Abi-Dargham A, Morrissey K, Abi-Saab D, Bremner JD, Bowers MB, Suckow RF, Stetson P, Heninger GR, Charney DS. Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans. Psychopharmacology. 135: 213-29. PMID 9498724 DOI: 10.1007/s002130050503  0.392
1998 Bremner JD, Krystal JH, Putnam FW, Southwick SM, Marmar C, Charney DS, Mazure CM. Measurement of dissociative states with the Clinician-Administered Dissociative States Scale (CADSS). Journal of Traumatic Stress. 11: 125-36. PMID 9479681 DOI: 10.1023/A:1024465317902  0.476
1998 Charney DS, Grillon CCG, Bremner JD. The neurobiological basis of anxiety and fear: Circuits, mechanisms, and neurochemical interactions (Part II) Neuroscientist. 4: 122-132. DOI: 10.1177/107385849800400208  0.363
1998 Charney DS, Davidson JR, Friedman M, Judge R, Keane T, McFarlane S, Martenyi F, Mellman TA, Petty F, Plewes J, Putnam F, Romano S, Van der Kolk BA, Yehuda R, Zohar J. A Consensus Meeting on Effective Research Practice in PTSD Cns Spectrums. 3: 6-10. DOI: 10.1017/S1092852900007264  0.305
1998 Berman R, Boutros N, Narasimhan M, Sanacora G, Charney D. 322. Transcranial magnetic stimulation in treatment-refractory depression Biological Psychiatry. 43: S97. DOI: 10.1016/S0006-3223(98)90770-3  0.492
1997 Gelernter J, Van Dyck C, van Kammen DP, Malison R, Price LH, Cubells JF, Berman R, Charney DS, Heninger G. Ciliary neurotrophic factor null allele frequencies in schizophrenia, affective disorders, and Alzheimer's disease. American Journal of Medical Genetics. 74: 497-500. PMID 9342199 DOI: 10.1002/(Sici)1096-8628(19970919)74:5<497::Aid-Ajmg8>3.0.Co;2-L  0.509
1997 Southwick SM, Krystal JH, Bremner JD, Morgan CA, Nicolaou AL, Nagy LM, Johnson DR, Heninger GR, Charney DS. Noradrenergic and serotonergic function in posttraumatic stress disorder. Archives of General Psychiatry. 54: 749-58. PMID 9283511 DOI: 10.1001/Archpsyc.1997.01830200083012  0.51
1997 Southwick SM, Morgan CA, Bremner AD, Grillon CG, Krystal JH, Nagy LM, Charney DS. Noradrenergic alterations in posttraumatic stress disorder. Annals of the New York Academy of Sciences. 821: 125-41. PMID 9238199 DOI: 10.1111/J.1749-6632.1997.Tb48274.X  0.469
1997 Krystal JH, Webb E, Grillon C, Cooney N, Casal L, Morgan CA, Southwick SM, Davis M, Charney DS. Evidence of acoustic startle hyperreflexia in recently detoxified early onset male alcoholics: modulation by yohimbine and m-chlorophenylpiperazine (mCPP). Psychopharmacology. 131: 207-15. PMID 9203230 DOI: 10.1007/S002130050285  0.48
1997 Bremner JD, Licinio J, Darnell A, Krystal JH, Owens MJ, Southwick SM, Nemeroff CB, Charney DS. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. The American Journal of Psychiatry. 154: 624-9. PMID 9137116 DOI: 10.1176/Ajp.154.5.624  0.473
1997 Barr LC, Heninger GR, Goodman W, Charney DS, Price LH. Effects of fluoxetine administration on mood response to tryptophan depletion in healthy subjects. Biological Psychiatry. 41: 949-54. PMID 9110100 DOI: 10.1016/S0006-3223(96)00224-7  0.58
1997 Bremner JD, Innis RB, Salomon RM, Staib LH, Ng CK, Miller HL, Bronen RA, Krystal JH, Duncan J, Rich D, Price LH, Malison R, Dey H, Soufer R, Charney DS. Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Archives of General Psychiatry. 54: 364-74. PMID 9107153 DOI: 10.1001/Archpsyc.1997.01830160092012  0.623
1997 Bremner JD, Innis RB, Ng CK, Staib LH, Salomon RM, Bronen RA, Duncan J, Southwick SM, Krystal JH, Rich D, Zubal G, Dey H, Soufer R, Charney DS. Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder. Archives of General Psychiatry. 54: 246-54. PMID 9075465  0.43
1997 Wang S, Mason J, Charney D, Yehuda R, Riney S, Southwick S. Relationships between hormonal profile and novelty seeking in combat-related posttraumatic stress disorder. Biological Psychiatry. 41: 145-51. PMID 9018384 DOI: 10.1016/S0006-3223(95)00648-6  0.328
1997 Southwick SM, Morgan A, Nicolaou AL, Charney DS. Consistency of memory for combat-related traumatic events in veterans of Operation Desert Storm American Journal of Psychiatry. 154: 173-177. PMID 9016264 DOI: 10.1176/Ajp.154.2.173  0.306
1997 Berman RM, Darnell AM, Miller HL, Anand A, Charney DS. Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial. The American Journal of Psychiatry. 154: 37-43. PMID 8988956 DOI: 10.1176/Ajp.154.1.37  0.353
1997 Salomon RM, Miller HL, Krystal JH, Heninger GR, Charney DS. Lack of behavioral effects of monoamine depletion in healthy subjects. Biological Psychiatry. 41: 58-64. PMID 8988796 DOI: 10.1016/0006-3223(95)00670-2  0.449
1997 Bremner JD, Randall P, Vermetten E, Staib L, Bronen RA, Mazure C, Capelli S, McCarthy G, Innis RB, Charney DS. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report. Biological Psychiatry. 41: 23-32. PMID 8988792 DOI: 10.1016/S0006-3223(96)00162-X  0.322
1997 Cappiello A, Malison RT, McDougle CJ, Vegso SJ, Charney DS, Heninger GR, Price LH. Seasonal variation in neuroendocrine and mood responses to i.v. L-tryptophan in depressed patients and healthy subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 475-83. PMID 8914120 DOI: 10.1016/S0893-133X(96)00057-7  0.566
1997 Abi-Dargham A, Charney DS, Krystal JH. Benzodiazepine Receptor Antagonists Cns Drugs. 8: 244-256. DOI: 10.2165/00023210-199708030-00007  0.408
1997 Zuzarte E, Cyril D’Souza D, Gil R, White J, AbiSaab D, Charney DS, Krystal JH. Evaluation of lorazepam blockade of M-chlorophenylpiperazine (MCPP) effects in schizophrenia Schizophrenia Research. 24: 218. DOI: 10.1016/S0920-9964(97)82626-6  0.394
1997 Zuzarte E, Cyril D’Souza D, Gil R, Genovese A, White J, Charney DS, Krystal JH. Dose-related ethanol effects in schizophrenic patients Schizophrenia Research. 24: 218. DOI: 10.1016/S0920-9964(97)82625-4  0.411
1997 Laruelle M, Abi-Dargham A, Krystal JH, Charney DS, Innis RB. In vivo evaluation of dopamine synaptic funcflon in untreated schizophrenic patients Schizophrenia Research. 24: 179. DOI: 10.1016/S0920-9964(97)82515-7  0.408
1997 Berman R, Charney DS. Current thinking on treatment-refractory depression Depression and Anxiety. 5: 153-153. DOI: 10.1002/(Sici)1520-6394(1997)5:4<153::Aid-Da1>3.0.Co;2-E  0.324
1996 Charney DS, Deutch A. A functional neuroanatomy of anxiety and fear: Implications for the pathophysiology and treatment of anxiety disorders Critical Reviews in Neurobiology. 10: 419-446. PMID 8978989 DOI: 10.1615/Critrevneurobiol.V10.I3-4.70  0.316
1996 Grillon C, Morgan CA, Southwick SM, Davis M, Charney DS. Baseline startle amplitude and prepulse inhibition in Vietnam veterans with posttraumatic stress disorder Psychiatry Research. 64: 169-178. PMID 8944395 DOI: 10.1016/S0165-1781(96)02942-3  0.339
1996 Krystal JH, Deutsch DN, Charney DS. The biological basis of panic disorder. The Journal of Clinical Psychiatry. 57: 23-31; discussion 32. PMID 8917129  0.432
1996 Miller HL, Delgado PL, Salomon RM, Heninger GR, Charney DS. Effects of alpha-methyl-para-tyrosine (AMPT) in drug-free depressed patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 14: 151-7. PMID 8866698 DOI: 10.1016/0893-133X(95)00072-L  0.382
1996 Heninger GR, Delgado PL, Charney DS. The revised monoamine theory of depression: A modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans Pharmacopsychiatry. 29: 2-11. PMID 8852528 DOI: 10.1055/S-2007-979535  0.393
1996 Karper LP, Freeman GK, Grillon C, Morgan CA, Charney DS, Krystal JH. Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis. The Journal of Neuropsychiatry and Clinical Neurosciences. 8: 60-6. PMID 8845703 DOI: 10.1176/Jnp.8.1.60  0.42
1996 Laruelle M, Abi-Dargham A, van Dyck CH, Gil R, D'Souza CD, Erdos J, McCance E, Rosenblatt W, Fingado C, Zoghbi SS, Baldwin RM, Seibyl JP, Krystal JH, Charney DS, Innis RB. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proceedings of the National Academy of Sciences of the United States of America. 93: 9235-40. PMID 8799184 DOI: 10.1073/Pnas.93.17.9235  0.445
1996 Bremner JD, Krystal JH, Southwick SM, Charney DS. Noradrenergic mechanisms in stress and anxiety: II. Clinical studies. Synapse (New York, N.Y.). 23: 39-51. PMID 8723134 DOI: 10.1002/(SICI)1098-2396(199605)23:1<39::AID-SYN5>3.0.CO;2-I  0.45
1996 Bremner JD, Krystal JH, Southwick SM, Charney DS. Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies. Synapse (New York, N.Y.). 23: 28-38. PMID 8723133 DOI: 10.1002/(Sici)1098-2396(199605)23:1<28::Aid-Syn4>3.0.Co;2-J  0.492
1996 Bremner JD, Krystal JH, Charney DS, Southwick SM. Neural mechanisms in dissociative amnesia for childhood abuse: relevance to the current controversy surrounding the "false memory syndrome". The American Journal of Psychiatry. 153: 71-82. PMID 8659644 DOI: 10.1176/Ajp.153.7.71  0.424
1996 Johnson DR, Rosenheck R, Fontana A, Lubin H, Charney D, Southwick S. Outcome of intensive inpatient treatment for combat-related posttraumatic stress disorder. The American Journal of Psychiatry. 153: 771-7. PMID 8633688 DOI: 10.1176/Ajp.153.6.771  0.305
1996 Miller HL, Delgado PL, Salomon RM, Berman R, Krystal JH, Heninger GR, Charney DS. Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression. Archives of General Psychiatry. 53: 117-28. PMID 8629887 DOI: 10.1001/Archpsyc.1996.01830020031005  0.484
1996 Bremner JD, Southwick SM, Darnell A, Charney DS. Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse. The American Journal of Psychiatry. 153: 369-75. PMID 8610824 DOI: 10.1176/Ajp.153.3.369  0.308
1996 Lam RW, Zis AP, Grewal A, Delgado PL, Charney DS, Krystal JH. Effects of rapid tryptophan depletion in patients with seasonal affective disorder in remission after light therapy. Archives of General Psychiatry. 53: 41-4. PMID 8540776 DOI: 10.1001/Archpsyc.1996.01830010043007  0.498
1996 Krystal JH, Webb E, Cooney NL, Kranzler HR, Southwick SW, Heninger GR, Charney DS. Serotonergic and noradrenergic dysregulation in alcoholism: m-chlorophenylpiperazine and yohimbine effects in recently detoxified alcoholics and healthy comparison subjects. The American Journal of Psychiatry. 153: 83-92. PMID 8540598 DOI: 10.1176/Ajp.153.1.83  0.418
1996 Morgan CA, Grillon C, Southwick SM, Davis M, Charney DS. Exaggerated acoustic startle reflex in Gulf War veterans with posttraumatic stress disorder American Journal of Psychiatry. 153: 64-68. PMID 8540594 DOI: 10.1176/Ajp.153.1.64  0.323
1996 Petrakis IL, Satel SL, Stine S, Kosten TR, Namanworth SN, Charney DS, Krystal JH. AMPT Effects on Cue-Induced Craving for Cocaine The American Journal On Addictions. 5: 313-320. DOI: 10.1111/J.1521-0391.1996.Tb00317.X  0.409
1996 Miller H, Damell A, Cappiello A, Bemman R, Anand A, Charney D. Serotonin function and vulnerability to depression Biological Psychiatry. 39: 528. DOI: 10.1016/0006-3223(96)84046-7  0.335
1995 Bremner JD, Krystal JH, Southwick SM, Charney DS. Functional neuroanatomical correlates of the effects of stress on memory. Journal of Traumatic Stress. 8: 527-53. PMID 8564272 DOI: 10.1007/Bf02102888  0.443
1995 Stine SM, Krystal JH, Kosten TR, Charney DS. Mazindol treatment for cocaine dependence Drug and Alcohol Dependence. 39: 245-252. PMID 8556974 DOI: 10.1016/0376-8716(95)01174-4  0.457
1995 Morgan CA, Grillon C, Southwick SM, Davis M, Charney DS. Fear-potentiated startle in posttraumatic stress disorder Biological Psychiatry. 38: 378-385. PMID 8547457 DOI: 10.1016/0006-3223(94)00321-S  0.335
1995 Salomon RM, Delgado PL, Licinio J, Krystal JH, Heninger GR, Charney DS. Effects of sleep deprivation on serotonin function in depression. Biological Psychiatry. 36: 840-6. PMID 7893848 DOI: 10.1016/0006-3223(94)90595-9  0.487
1995 Bremner JD, Randall P, Scott TM, Bronen RA, Seibyl JP, Southwick SM, Delaney RC, McCarthy G, Charney DS, Innis RB. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. The American Journal of Psychiatry. 152: 973-81. PMID 7793467 DOI: 10.1176/Ajp.152.7.973  0.357
1995 Krystal JH, Woods SW, Kosten TR, Rosen MI, Seibyl JP, van Dyck CC, Price LH, Zubal IG, Hoffer PB, Charney DS. Opiate dependence and withdrawal: preliminary assessment using single photon emission computerized tomography (SPECT). The American Journal of Drug and Alcohol Abuse. 21: 47-63. PMID 7762544 DOI: 10.3109/00952999509095229  0.592
1995 Satel SL, Krystal JH, Delgado PL, Kosten TR, Charney DS. Tryptophan depletion and attenuation of cue-induced craving for cocaine. The American Journal of Psychiatry. 152: 778-83. PMID 7726319 DOI: 10.1176/Ajp.152.5.778  0.399
1995 Mcdougle CJ, Krystal JH, Price LH, Heninger GR, Charney DS. Noradrenergic response to acute ethanol administration in healthy subjects: comparison with intravenous yohimbine. Psychopharmacology. 118: 127-135. PMID 7617798 DOI: 10.1007/Bf02245830  0.487
1995 Morgan CA, Grillon C, Southwick SM, Nagy LM, Davis M, Krystal JH, Charney DS. Yohimbine facilitated acoustic startle in combat veterans with post-traumatic stress disorder Psychopharmacology. 117: 466-471. PMID 7604149 DOI: 10.1007/Bf02246220  0.497
1995 Goodman WK, McDougle CJ, Price LH, Barr LC, Hills OF, Caplik JF, Charney DS, Heninger GR. m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: absence of symptom exacerbation. Biological Psychiatry. 38: 138-49. PMID 7578657 DOI: 10.1016/0006-3223(94)00235-U  0.549
1995 Goddard AW, Charney DS, Germine M, Woods SW, Heninger GR, Krystal JH, Goodman WK, Price LH. Effects of tryptophan depletion on responses to yohimbine in healthy human subjects Biological Psychiatry. 38: 74-85. PMID 7578653 DOI: 10.1016/0006-3223(94)00223-P  0.596
1995 Randall PK, Bremner JD, Krystal JH, Nagy LM, Heninger GR, Nicolaou AL, Charney DS. Effects of the benzodiazepine antagonist flumazenil in PTSD. Biological Psychiatry. 38: 319-24. PMID 7495926 DOI: 10.1016/0006-3223(94)00306-N  0.516
1995 Wang S, Mason J, Southwick S, Johnson D, Lubin H, Charney D. Relationships between thyroid hormones and symptoms in combat-related posttraumatic stress disorder Psychosomatic Medicine. 57: 398-402. PMID 7480570 DOI: 10.1097/00006842-199507000-00012  0.312
1995 D'Souza DC, Charney D, Krystal J. Glycine Site Agonists of the NMDA Receptor: A Review Cns Drug Reviews. 1: 227-260. DOI: 10.1111/J.1527-3458.1995.Tb00285.X  0.393
1994 Goldstein RB, Weissman MM, Adams PB, Horwath E, Lish JD, Charney D, Woods SW, Sobin C, Wickramaratne PJ. Psychiatric Disorders in Relatives of Probands with Panic Disorder and/or Major Depression Archives of General Psychiatry. 51: 383-394. PMID 8179462 DOI: 10.1001/Archpsyc.1994.03950050043005  0.356
1994 Barr LC, Goodman WK, McDougle CJ, Delgado PL, Heninger GR, Charney DS, Price LH. Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors. Archives of General Psychiatry. 51: 309-17. PMID 8161291 DOI: 10.1001/Archpsyc.1994.03950040053007  0.554
1994 Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Charney DS. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Archives of General Psychiatry. 51: 199-214. PMID 8122957 DOI: 10.1001/Archpsyc.1994.03950030035004  0.428
1994 Krystal JH, Webb E, Cooney N, Kranzler HR, Charney DS. Specificity of ethanollike effects elicited by serotonergic and noradrenergic mechanisms. Archives of General Psychiatry. 51: 898-911. PMID 7944878 DOI: 10.1001/Archpsyc.1994.03950110058008  0.448
1994 Delgado PL, Price LH, Miller HL, Salomon RM, Aghajanian GK, Heninger GR, Charney DS. Serotonin and the neurobiology of depression. Effects of tryptophan depletion in drug-free depressed patients. Archives of General Psychiatry. 51: 865-74. PMID 7944875 DOI: 10.1001/Archpsyc.1994.03950110025005  0.563
1994 Anand A, Charney DS, Delgado PL, McDougle CJ, Heninger GR, Price LH. Neuroendocrine and behavioral responses to intravenous m-chlorophenylpiperazine (mCPP) in depressed patients and healthy comparison subjects. The American Journal of Psychiatry. 151: 1626-30. PMID 7943451 DOI: 10.1176/Ajp.151.11.1626  0.557
1994 Southwick SM, Bremner D, Krystal JH, Charney DS. Psychobiologic research in post-traumatic stress disorder Psychiatric Clinics of North America. 17: 251-264. PMID 7937357 DOI: 10.1016/S0193-953X(18)30112-6  0.524
1994 Goddard AW, Sholomskas DE, Walton KE, Augeri FM, Charney DS, Heninger GR, Goodman WK, Price LH. Effects of tryptophan depletion in panic disorder. Biological Psychiatry. 36: 775-7. PMID 7858076 DOI: 10.1016/0006-3223(94)90091-4  0.513
1994 Germine M, Goddard AW, Sholomskas DE, Woods SW, Charney DS, Heninger GR. Response to meta-chlorophenylpiperazine in panic disorder patients and healthy subjects: Influence of reduction in intravenous dosage Psychiatry Research. 54: 115-133. PMID 7761547 DOI: 10.1016/0165-1781(94)90001-9  0.308
1994 Karper LP, Charney DS. Biological correlates of neurosis Current Opinion in Psychiatry. 7: 140-143. DOI: 10.1097/00001504-199403000-00006  0.339
1994 Charney DS. Abnormal noradrenergic function in panic disorder and PTSD European Neuropsychopharmacology. 4: 257-258. DOI: 10.1016/0924-977X(94)90078-7  0.327
1994 Krystal JH, Southwick SM, Charney DS. Alcohol Dependence May Be the Missing Link between Posttraumatic Stress Disorder and Panic-Reply Archives of General Psychiatry. 51: 430. DOI: 10.1001/Archpsyc.1994.03950050090014  0.527
1993 Charney DS, Deutch AY, Krystal JH, Southwick SM, Davis M. Psychobiologic Mechanisms of Posttraumatic Stress Disorder Archives of General Psychiatry. 50: 294-305. PMID 8466391 DOI: 10.1001/Archpsyc.1993.01820160064008  0.485
1993 Southwick SM, Krystal JH, Morgan CA, Johnson D, Nagy LM, Nicolaou A, Heninger GR, Charney DS. Abnormal noradrenergic function in posttraumatic stress disorder. Archives of General Psychiatry. 50: 266-74. PMID 8466387 DOI: 10.1001/Archpsyc.1993.01820160036003  0.515
1993 Yehuda R, Southwick SM, Krystal JH, Bremner D, Charney DS, Mason JW. Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder. The American Journal of Psychiatry. 150: 83-6. PMID 8417586 DOI: 10.1176/Ajp.150.1.83  0.535
1993 Goddard AW, Woods SW, Sholomskas DE, Goodman WK, Charney DS, Heninger GR. Effects of the serotonin reuptake inhibitor fluvoxamine on yohimbine-induced anxiety in panic disorder Psychiatry Research. 48: 119-133. PMID 8416022 DOI: 10.1016/0165-1781(93)90036-G  0.391
1993 Friedman MJ, Charney DS, Southwick SM. Pharmacotherapy for recently evacuated military casualties Military Medicine. 158: 493-497. PMID 8351054 DOI: 10.1093/Milmed/158.7.493  0.373
1993 Weissman MM, Wickramaratne P, Adams PB, Lish JD, Horwath E, Charney D, Woods SW, Leeman E, Frosch E. The Relationship between Panic Disorder and Major Depression: A New Family Study Archives of General Psychiatry. 50: 767-780. PMID 8215801 DOI: 10.1001/Archpsyc.1993.01820220017003  0.36
1993 Salomon RM, Miller HL, Delgado PL, Charney D. The use of tryptophan depletion to evaluate central serotonin function in depression and other neuropsychiatric disorders. International Clinical Psychopharmacology. 8: 41-6. PMID 8201246 DOI: 10.1097/00004850-199311002-00006  0.372
1993 Licinio J, Seibyl JP, Altemus M, Charney DS, Krystal JH. Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients. The American Journal of Psychiatry. 150: 1408-10. PMID 8102512 DOI: 10.1176/ajp.150.9.1408  0.364
1993 Krystal JH, Seibyl JP, Price LH, Woods SW, Heninger GR, Aghajanian GK, Charney DS. m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients. Evidence implicating serotonergic systems in the positive symptoms of schizophrenia. Archives of General Psychiatry. 50: 624-35. PMID 8102048 DOI: 10.1001/Archpsyc.1993.01820200034004  0.633
1993 Seibyl JP, Satel SL, Anthony D, Southwick SM, Krystal JH, Charney DS. Effects of cocaine on hospital course in schizophrenia. The Journal of Nervous and Mental Disease. 181: 31-7. PMID 8093475 DOI: 10.1097/00005053-199301000-00006  0.418
1993 Morgan CA, Southwick SM, Grillon C, Davis M, Krystal JH, Charney DS. Yohimbine - facilitated acoustic startle reflex in humans Psychopharmacology. 110: 342-346. PMID 7831429 DOI: 10.1007/Bf02251291  0.485
1993 NAGY LM, MORGAN CA, SOUTHWICK SM, CHARNEY DS. Open Prospective Trial of Fluoxetine for Posttraumatic Stress Disorder Journal of Clinical Psychopharmacology. 13: 107???113. DOI: 10.1097/00004714-199304000-00004  0.404
1993 NAGY LM, KRYSTAL JH, CHARNEY DS, MERIKANGAS KR, WOODS SW. Long-Term Outcome of Panic Disorder After Short-Term Imipramine and Behavioral Group Treatment Journal of Clinical Psychopharmacology. 13: 16???24. DOI: 10.1097/00004714-199302000-00003  0.482
1992 Woods SW, Nagy LM, Koleszar AS, Krystal JH, Heninger GR, Charney DS. Controlled trial of alprazolam supplementation during imipramine treatment of panic disorder Journal of Clinical Psychopharmacology. 12: 32-38. PMID 1552038 DOI: 10.1097/00001573-199202000-00006  0.51
1992 Krystal JH, Leaf PJ, Bruce ML, Charney DS. Effects of age and alcoholism on the prevalence of panic disorder. Acta Psychiatrica Scandinavica. 85: 77-82. PMID 1546554 DOI: 10.1111/J.1600-0447.1992.Tb01447.X  0.466
1992 Bremner JD, Southwick S, Brett E, Fontana A, Rosenheck R, Charney DS. Dissociation and posttraumatic stress disorder in Vietnam combat veterans. The American Journal of Psychiatry. 149: 328-32. PMID 1536269 DOI: 10.1176/Ajp.149.3.328  0.324
1992 Seibyl JP, Brenner L, Krystal JH, Johnson R, Charney DS. Mazindol and cocaine addiction in schizophrenia. Biological Psychiatry. 31: 1179-81. PMID 1525287 DOI: 10.1016/0006-3223(92)90171-U  0.389
1992 Heninger GR, Delgado PL, Charney DS, Price LH, Aghajanian GK. Tryptophan-deficient diet and amino acid drink deplete plasma tryptophan and induce a relapse of depression in susceptible patients. Journal of Chemical Neuroanatomy. 5: 347-8. PMID 1524722 DOI: 10.1016/0891-0618(92)90025-L  0.506
1992 Germine M, Goddard AW, Woods SW, Charney DS, Heninger GR. Anger and anxiety responses to m-chlorophenylpiperazine in generalized anxiety disorder Biological Psychiatry. 32: 457-461. PMID 1486151 DOI: 10.1016/0006-3223(92)90133-K  0.322
1992 Grillon C, Ameli R, Charney DS, Krystal J, Braff D. Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biological Psychiatry. 32: 939-43. PMID 1467378 DOI: 10.1016/0006-3223(92)90183-Z  0.433
1992 McCance-Katz E, Price LH, Charney DS, Heninger GR. Serotonergic function during lithium augmentation of refractory depression Psychopharmacology. 108: 93-97. PMID 1410150 DOI: 10.1007/Bf02245291  0.548
1992 Krystal JH, McDougle CJ, Woods SW, Price LH, Heninger GR, Charney DS. Dose-response relationship for oral idazoxan effects in healthy human subjects: comparison with oral yohimbine Psychopharmacology. 108: 313-319. PMID 1355923 DOI: 10.1007/Bf02245117  0.6
1992 Charney DS, Woods SW, Krystal JH, Nagy LM, Heninger GR. Noradrenergic neuronal dysregulation in panic disorder: The effects of intravenous yohimbine and clonidine in panic disorder patients Acta Psychiatrica Scandinavica. 86: 273-282. PMID 1333719 DOI: 10.1111/J.1600-0447.1992.Tb03266.X  0.515
1992 Krystal JH, McDougle CJ, Kosten TR, Price LH, Aghajanian GK, Charney DS. Baclofen-assisted detoxification from opiates. A pilot study. Journal of Substance Abuse Treatment. 9: 139-42. PMID 1324986 DOI: 10.1016/0740-5472(92)90081-X  0.592
1991 Delgado PL, Goodman WK, Price LH, Heninger GR, Charney DS. Fluvoxamine/pimozide treatment of concurrent Tourette's and obsessive-compulsive disorder. The British Journal of Psychiatry : the Journal of Mental Science. 157: 762-5. PMID 2126219 DOI: 10.1192/Bjp.157.5.762  0.533
1991 Satel SL, Price LH, Palumbo JM, McDougle CJ, Krystal JH, Gawin F, Charney DS, Heninger GR, Kleber HD. Clinical phenomenology and neurobiology of cocaine abstinence: a prospective inpatient study. The American Journal of Psychiatry. 148: 1712-6. PMID 1957935 DOI: 10.1176/Ajp.148.12.1712  0.552
1991 Price LH, Charney DS, Delgado PL, Heninger GR. Serotonin function and depression: neuroendocrine and mood responses to intravenous L-tryptophan in depressed patients and healthy comparison subjects American Journal of Psychiatry. 148: 1518-1525. PMID 1928466 DOI: 10.1176/Ajp.148.11.1518  0.569
1991 Woods SW, Charney DS, Silver JM, Krystal JH, Heninger GR. Behavioral, biochemical, and cardiovascular responses to the benzodiazepine receptor antagonist flumazenil in panic disorder Psychiatry Research. 36: 115-127. PMID 1850142 DOI: 10.1016/0165-1781(91)90124-8  0.497
1991 Krystal JH, Woods SW, Hill CL, Charney DS. Characteristics of panic attack subtypes: Assessment of spontaneous panic, situational panic, sleep panic, and limited symptom attacks Comprehensive Psychiatry. 32: 474-480. PMID 1778074 DOI: 10.1016/0010-440X(91)90026-9  0.464
1991 Seibyl JP, Krystal JH, Price LH, Woods SW, D'Amico C, Heninger GR, Charney DS. Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects Psychiatry Research. 38: 227-236. PMID 1754635 DOI: 10.1016/0165-1781(91)90013-F  0.593
1991 Deutch AY, Moghaddam B, Innis RB, Krystal JH, Aghajanian GK, Bunney BS, Charney DS. Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia. Schizophrenia Research. 4: 121-56. PMID 1674882 DOI: 10.1016/0920-9964(91)90030-U  0.429
1991 Hand I, Linden M, Simons G, Hautzinger M, Heckel-Guhrenz S, Kraemer S, Schickor I, Rief W, Leibl C, Fichter MM, Büttner-Westphal H, Goodman W, Rasmussen S, Price L, Mazure L, ... ... Charney D, et al. Ausbildungsinstitut für Klinische Verhaltenstherapie in NRW (AFKV in NRW e.V.) Verhaltenstherapie. 1: 256-256. DOI: 10.1159/000257983  0.415
1991 Hand I, Linden M, Simons G, Hautzinger M, Heckel-Guhrenz S, Kraemer S, Schickor I, Rief W, Leibl C, Fichter MM, Büttner-Westphal H, Goodman W, Rasmussen S, Price L, Mazure L, ... ... Charney D, et al. Bayerische Private Akademie für Psychotherapie (BAP) Verhaltenstherapie. 1: 162-162. DOI: 10.1159/000257976  0.445
1991 Goodman W, Rasmussen S, Price L, Mazure L, Heninger G, Charney D. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Verhaltenstherapie. 1: 226-233. DOI: 10.1159/000257973  0.44
1991 McDOUGLE CJ, PRICE LH, GOODMAN WK, CHARNEY DS, HENINGER GR. A Controlled Trial of Lithium Augmentation in Fluvoxamine-Refractory Obsessive-Compulsive Disorder Journal of Clinical Psychopharmacology. 11: 175???184. DOI: 10.1097/00004714-199106000-00005  0.57
1991 Wolfe J, Charney DS. Use of Neuropsychological Assessment in Posttraumatic Stress Disorder Psychological Assessment. 3: 573-580. DOI: 10.1037/1040-3590.3.4.573  0.327
1991 Licinio J, Krystal J, Seibyl J, Altemus M, Charney D. Elevated central levels of interleukin-2 in drug-free schizophrenic patients Schizophrenia Research. 4: 372. DOI: 10.1016/0920-9964(91)90301-7  0.337
1991 Krystal J, Seibyl J, Price L, Woods S, Heninger G, Charney D. MCPP effects in schizophrenic patients before and after typical and atypical neuroleptic treatment Schizophrenia Research. 4: 350. DOI: 10.1016/0920-9964(91)90266-T  0.545
1991 Nagy LM, Krystal JH, Charney DS, Woods SW. Follow-up Study of Patients With Panic Disorder-Reply Archives of General Psychiatry. 48: 861-862. DOI: 10.1001/Archpsyc.1991.01810330085018  0.464
1990 Heninger GR, Charney DS, Price LH, Delgado P, Woods S, Goodman W. Effects of serotonergic agonists on neuroendocrine responses of rhesus monkeys and patients with depression and anxiety disorders. Psychopharmacology Series. 7: 94-104. PMID 2687871 DOI: 10.1007/978-3-642-74430-3_10  0.558
1990 Delgado PL, Charney DS, Price LH, Landis H, Heninger GR. Neuroendocrine and behavioral effects of dietary tryptophan restriction in healthy subjects. Life Sciences. 45: 2323-32. PMID 2601581 DOI: 10.1016/0024-3205(89)90114-8  0.471
1990 Price LH, Charney DS, Delgado PL, Heninger GR. Lithium and serotonin function: implications for the serotonin hypothesis of depression Psychopharmacology. 101: 3-12. PMID 2404294 DOI: 10.1007/Bf02245781  0.522
1990 Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Opioid antagonist challenges in buprenorphine maintained patients. Drug and Alcohol Dependence. 25: 73-8. PMID 2323312 DOI: 10.1016/0376-8716(90)90144-4  0.583
1990 Seibyl JP, Krystal JH, Charney DS. Marijuana (cannabis) use is anecdotally said to precipitate anxiety symptoms in patients with panic disorder. Is there any research evidence to support this? Also, can marijuana use precipitate or expose paranoia in patients with an underlying bipolar disorder? Journal of Clinical Psychopharmacology. 10: 78. PMID 2307743 DOI: 10.1097/00004714-199002000-00033  0.51
1990 Price LH, Charney DS, Delgado PL, Heninger GR. Fenfluramine augmentation in tricyclic-refractory depression Journal of Clinical Psychopharmacology. 10: 312-317. PMID 2258448 DOI: 10.1097/00004714-199010000-00002  0.558
1990 Charney DS, Woods SW, Krystal JH, Heninger GR. Serotonin function and human anxiety disorders Annals of the New York Academy of Sciences. 600: 558-573. PMID 2252335 DOI: 10.1111/J.1749-6632.1990.Tb16910.X  0.489
1990 Price LH, Charney DS, Delgado PL, Goodman WK, Krystal JH, Woods SW, Heninger GR. Clinical studies of 5-HT function using I.V. l-Tryptophan Progress in Neuropsychopharmacology and Biological Psychiatry. 14: 459-472. PMID 2236580 DOI: 10.1016/0278-5846(90)90002-X  0.592
1990 Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heninger GR. Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Archives of General Psychiatry. 47: 411-8. PMID 2184795 DOI: 10.1001/Archpsyc.1990.01810170011002  0.553
1990 Charney DS, Krystal JH, Delgado PL, Heninger GR. Serotonin-specific drugs for anxiety and depressive disorders Annual Review of Medicine. 41: 437-446. PMID 2139556 DOI: 10.1146/Annurev.Me.41.020190.002253  0.528
1990 Nierenberg AA, Price LH, Charney DS, Heninger GR. After lithium augmentation: a retrospective follow-up of patients with antidepressant-refractory depression Journal of Affective Disorders. 18: 167-175. PMID 2139061 DOI: 10.1016/0165-0327(90)90033-5  0.54
1990 Goodman WK, Price LH, Delgado PL, Palumbo J, Krystal JH, Nagy LM, Rasmussen SA, Heninger GR, Charney DS. Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. Archives of General Psychiatry. 47: 577-85. PMID 2112374 DOI: 10.1001/Archpsyc.1990.01810180077011  0.658
1990 McDougle CJ, Goodman WK, Price LH, Delgado PL, Krystal JH, Charney DS, Heninger GR. Neuroleptic addition in fluvoxamine-refractory obsessive-compulsive disorder. The American Journal of Psychiatry. 147: 652-4. PMID 1970224 DOI: 10.1176/Ajp.147.5.652  0.618
1990 Charney DS, Krystal JJ, Southwick SM, Nagy LM, Woods SW, Heninger GR. Serotonin Function in Panic and Generalized Anxiety Disorders Psychiatric Annals. 20: 593-602. DOI: 10.3928/0048-5713-19901001-11  0.346
1990 Heninger GR, Charney DS. Noradrenergic mechanisms in the pathogenesis and treatment of panic disorder Journal of Psychiatric Research. 24: 92-93. DOI: 10.1016/0022-3956(90)90104-X  0.323
1990 Price LH, Charney DS, Delgado PL, Heninger GR. Lithium Treatment Effect on Serotonin Function Archives of General Psychiatry. 47: 290. DOI: 10.1001/Archpsyc.1990.01810150090017  0.5
1989 Price LH, Charney DS, Delgado PL, Heninger GR. Lithium Treatment and Serotoninergic Function: Neuroendocrine and Behavioral Responses to Intravenous Tryptophan in Affective Disorder Archives of General Psychiatry. 46: 13-19. PMID 2910219 DOI: 10.1001/Archpsyc.1989.01810010015002  0.532
1989 Nagy LM, Krystal JH, Woods SW, Charney DS. Clinical and Medication Outcome After Short-term Alprazolam and Behavorial Group Treatment in Panic Disorder: 2.5-Year Naturalistic Follow-up Study Archives of General Psychiatry. 46: 993-999. PMID 2818144 DOI: 10.1001/Archpsyc.1989.01810110035005  0.536
1989 Seibyl JP, Krystal JH, Price LH, Charney DS. Use of yohimbine to counteract nortriptyline-induced orthostatic hypotension Journal of Clinical Psychopharmacology. 9: 67-68. PMID 2708559 DOI: 10.1097/00004714-198902000-00026  0.533
1989 Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Archives of General Psychiatry. 46: 1006-11. PMID 2684084 DOI: 10.1001/Archpsyc.1989.01810110048007  0.513
1989 Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Rapid detoxification from opioid dependence. The American Journal of Psychiatry. 146: 1349. PMID 2675644 DOI: 10.1176/ajp.146.10.1349a  0.472
1989 Glazer WM, Bowers MB, Charney DS, Heninger GR. The effect of neuroleptic discontinuation on psychopathology, involuntary movements, and biochemical measures in patients with persistent tardive dyskinesia. Biological Psychiatry. 26: 224-33. PMID 2568132 DOI: 10.1016/0006-3223(89)90034-6  0.314
1989 Charney DS, Innis RB, Duman RS, Woods SW, Heninger GR. Platelet alpha-2-receptor binding and adenylate cyclase activity in panic disorder. Psychopharmacology. 98: 102-7. PMID 2543016 DOI: 10.1007/Bf00442014  0.33
1989 Charney DS, Woods SW, Heninger GR. Noradrenergic function in generalized anxiety disorder: Effects of yohimbine in healthy subjects and patients with generalized anxiety disorder Psychiatry Research. 27: 173-182. PMID 2540501 DOI: 10.1016/0165-1781(89)90132-7  0.397
1989 Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale. II. Validity. Archives of General Psychiatry. 46: 1012-6. PMID 2510699 DOI: 10.1001/Archpsyc.1989.01810110054008  0.55
1989 Woods SW, Krystal JH, Heninger GR, Charney DS. Effects of alprazolam and clonidine on carbon dioxide-induced increases in anxiety ratings in healthy human subjects Life Sciences. 45: 233-242. PMID 2503670 DOI: 10.1016/0024-3205(89)90255-5  0.457
1989 Price LH, Charney DS, Delgado PL, Anderson GM, Heninger GR. Effects of desipramine and fluvoxamine treatment on the prolactin response to tryptophan. Serotonergic function and the mechanism of antidepressant action. Archives of General Psychiatry. 46: 625-31. PMID 2500111 DOI: 10.1001/Archpsyc.1989.01810070051009  0.515
1989 Goodman WK, Price LH, Rasmussen SA, Delgado PL, Heninger GR, Charney DS. Efficacy of fluvoxamine in obsessive-compulsive disorder. A double-blind comparison with placebo. Archives of General Psychiatry. 46: 36-44. PMID 2491940 DOI: 10.1001/Archpsyc.1989.01810010038006  0.597
1989 Goodman WK, Price LH, Charney DS. Fluvoxamine in Obsessive Compulsive Disorder Psychiatric Annals. 19: 92-96. DOI: 10.3928/0048-5713-19890201-10  0.512
1989 Koster K, Woods SW, Smith EO, Zubal IG, Krystal JH, Charney DS, Hoffer PB. REGIONAL CEREBRAL BLOOD FLOW CHANGES IN PATIENTS WITH PANIC DISORDER Clinical Nuclear Medicine. 14: 234. DOI: 10.1097/00003072-198903000-00039  0.366
1989 Heninger G, Delgado P, Charney D, Price L, Aghajanian G, Landis H. Behavioral effects of acute tryptophan depletion in depressed patients Biological Psychiatry. 25: A143. DOI: 10.1016/0006-3223(89)91774-5  0.531
1988 Price LH, Charney DS, Heninger GR. Effects of trazodone treatment on serotonergic function in depressed patients Psychiatry Research. 24: 165-175. PMID 3406237 DOI: 10.1016/0165-1781(88)90059-5  0.54
1988 Charney DS, Goodman WK, Price LH, Woods SW, Rasmussen SA, Heninger GR. Serotonin Function in Obsessive-Compulsive Disorder: A Comparison of the Effects of Tryptophan and m-Chlorophenylpiperazine in Patients and Healthy Subjects Archives of General Psychiatry. 45: 177-185. PMID 3337615 DOI: 10.1001/Archpsyc.1988.01800260095012  0.538
1988 Woods SW, Charney DS, Goodman WK, Heninger GR. Carbon Dioxide—Induced Anxiety: Behavioral, Physiologic, and Biochemical Effects of Carbon Dioxide in Patients With Panic Disorders and Healthy Subjects Archives of General Psychiatry. 45: 43-52. PMID 3122696 DOI: 10.1001/Archpsyc.1988.01800250051007  0.331
1988 Heninger GR, Charney DS, Price LH. Noradrenergic and serotonergic receptor system function in panic disorder and depression Acta Psychiatrica Scandinavica. 77: 138-150. PMID 3048049 DOI: 10.1111/J.1600-0447.1988.Tb08559.X  0.6
1988 Delgado PL, Price LH, Charney DS, Heninger GR. Efficacy of fluvoxamine in treatment-refractory depression Journal of Affective Disorders. 15: 55-60. PMID 2970493 DOI: 10.1016/0165-0327(88)90009-2  0.554
1988 Brown SL, Charney DS, Woods SW, Heninger GR, Tallman J. Lymphocyte beta-adrenergic receptor binding in panic disorder. Psychopharmacology. 94: 24-8. PMID 2894700 DOI: 10.1007/Bf00735875  0.332
1988 Heninger GR, Charney DS. Monoamine receptor systems and anxiety disorders Psychiatric Clinics of North America. 11: 309-326. PMID 2843838 DOI: 10.1016/S0193-953X(18)30499-4  0.41
1988 Heninger GR, Charney DS, Price LH. α2-Adrenergic Receptor Sensitivity in Depression: The Plasma MHPG, Behavioral, and Cardiovascular Responses to Yohimbine Archives of General Psychiatry. 45: 718-726. PMID 2840050 DOI: 10.1001/Archpsyc.1988.01800320028003  0.594
1988 Woods SW, Charney DS. Applications of the pharmacologic challenge strategy in panic disorders research Journal of Anxiety Disorders. 2: 31-49. DOI: 10.1016/0887-6185(88)90012-6  0.348
1988 Charney DS, Price LH, Breier A. The Course of Panic Attacks and Agoraphobia-Reply Archives of General Psychiatry. 45: 502. DOI: 10.1001/Archpsyc.1988.01800290124016  0.564
1987 Glazer WM, Charney DS, Heninger GR. Noradrenergic Function in Schizophrenia Archives of General Psychiatry. 44: 898-904. PMID 3662745 DOI: 10.1001/Archpsyc.1987.01800220068010  0.323
1987 Price LH, Goodman WK, Charney DS, Rasmussen SA, Heninger GR. Treatment of severe obsessive-compulsive disorder with fluvoxamine. The American Journal of Psychiatry. 144: 1059-61. PMID 3111279 DOI: 10.1176/ajp.144.8.1059  0.493
1987 Charney DS, Woods SW, Goodman WK, Heninger GR. Serotonin function in anxiety - II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects Psychopharmacology. 92: 14-24. PMID 3110824 DOI: 10.1007/Bf00215473  0.403
1987 Charney DS, Woods SW, Goodman WK, Heninger GR. Neurobiological mechanisms of panic anxiety: Biochemical and behavioral correlates of yohimbine-induced panic attacks American Journal of Psychiatry. 144: 1030-1036. PMID 3037926 DOI: 10.1176/Ajp.144.8.1030  0.365
1987 Innis RB, Charney DS, Heninger GR. Differential 3H-imipramine platelet binding in patients with panic disorder and depression Psychiatry Research. 21: 33-41. PMID 3037580 DOI: 10.1016/0165-1781(87)90059-X  0.374
1987 Woods SW, Charney DS, Mcpherson CA, Gradman AH, Heninger GR. Situational Panic Attacks: Behavioral, Physiologic, and Biochemical Characterization Archives of General Psychiatry. 44: 365-375. PMID 2882735 DOI: 10.1001/Archpsyc.1987.01800160077010  0.325
1987 Rasmussen SA, Goodman WK, Woods SW, Heninger GR, Charney DS. Effects of yohimbine in obsessive compulsive disorder Psychopharmacology. 93: 308-313. PMID 2829264 DOI: 10.1007/Bf00187248  0.424
1987 Price LH, Charney DS, Heninger GR. Reserpine augmentation of desipramine in refractory depression: clinical and neurobiological effects Psychopharmacology. 92: 431-437. PMID 2442788 DOI: 10.1007/Bf00176473  0.564
1986 Charney DS, Heninger GR. Serotonin Function in Panic Disorders: The Effect of Intravenous Tryptophan in Healthy Subjects and Patients With Panic Disorder Before and During Alprazolam Treatment Archives of General Psychiatry. 43: 1059-1065. PMID 3767596 DOI: 10.1001/Archpsyc.1986.01800110045006  0.407
1986 Breier A, Charney DS, Heninger GR. Agoraphobia With Panic Attacks: Development, Diagnostic Stability, and Course of Illness Archives of General Psychiatry. 43: 1029-1036. PMID 3767595 DOI: 10.1001/Archpsyc.1986.01800110015003  0.39
1986 Innis RB, Bunney BS, Charney DS, Price LH, Glazer WM, Sternberg DE, Rubin AL, Heninger GR. Does the cholecystokinin antagonist proglumide possess antipsychotic activity? Psychiatry Research. 18: 1-7. PMID 3737785 DOI: 10.1016/0165-1781(86)90056-9  0.51
1986 Price LH, Charney DS, Heninger GR. Variability of response to lithium augmentation in refractory depression American Journal of Psychiatry. 143: 1387-1392. PMID 3096155 DOI: 10.1176/Ajp.143.11.1387  0.545
1986 Woods SW, Charney DS, Loke J, Goodman WK, Redmond DE, Heninger GR. Carbon Dioxide Sensitivity in Panic Anxiety: Ventilatory and Anxiogenic Response to Carbon Dioxide in Healthy Subjects and Patients With Panic Anxiety Before and After Alprazolam Treatment Archives of General Psychiatry. 43: 900-909. PMID 3092780 DOI: 10.1001/Archpsyc.1986.01800090090013  0.334
1986 Charney DS, Price LH, Heninger GR. Desipramine-Yohimbine Combination Treatment of Refractory Depression: Implications for the β-Adrenergic Receptor Hypothesis of Antidepressant Action Archives of General Psychiatry. 43: 1155-1161. PMID 3022664 DOI: 10.1001/Archpsyc.1986.01800120041009  0.546
1986 Charney DS, Heninger GR. Abnormal Regulation of Noradrenergic Function in Panic Disorders: Effects of Clonidine in Healthy Subjects and Patients With Agoraphobia and Panic Disorder Archives of General Psychiatry. 43: 1042-1054. PMID 3021083 DOI: 10.1001/Archpsyc.1986.01800110028005  0.367
1986 Charney DS, Heninger GR. α2-Adrenergic and Opiate Receptor Blockade: Synergistic Effects on Anxiety in Healthy Subjects Archives of General Psychiatry. 43: 1037-1041. PMID 3021082 DOI: 10.1001/Archpsyc.1986.01800110023004  0.338
1986 Price LH, Charney DS, Rubin AL, Heninger GR. α2-Adrenergic Receptor Function in Depression: The Cortisol Response to Yohimbine Archives of General Psychiatry. 43: 849-858. PMID 3019271 DOI: 10.1001/Archpsyc.1986.01800090035006  0.557
1986 Price LH, Charney DS, Heninger GR. Effects of trazodone treatment on alpha-2 adrenoceptor function in depressed patients Psychopharmacology. 89: 38-44. PMID 3016788 DOI: 10.1007/Bf00175186  0.532
1986 Goodman WK, Charney DS, Price LH, Woods SW, Heninger GR. Ineffectiveness of clonidine in the treatment of the benzodiazepine withdrawal syndrome: Report of three cases American Journal of Psychiatry. 143: 900-903. PMID 2872826 DOI: 10.1176/Ajp.143.7.900  0.502
1985 Price LH, Charney DS, Heninger GR. Effects of tranylcypromine treatment on neuroendocrine, behavioral, and autonomic responses to tryptophan in depressed patients Life Sciences. 37: 809-818. PMID 4033356 DOI: 10.1016/0024-3205(85)90515-6  0.571
1985 Price LH, Charney DS, Heninger GR. Efficacy of lithium-tranylcypromine treatment in refractory depression American Journal of Psychiatry. 142: 619-623. PMID 3920923 DOI: 10.1176/Ajp.142.5.619  0.548
1985 Lawrence Rubin A, Price LH, Charney DS, Heninger GR. Noradrenergic function and the cortisol response to dexamethasone in depression Psychiatry Research. 15: 5-15. PMID 2989963 DOI: 10.1016/0165-1781(85)90034-4  0.554
1985 Charney DS, Heninger GR, Jatlow PI. Increased Anxiogenic Effects of Caffeine in Panic Disorders Archives of General Psychiatry. 42: 233-243. PMID 2983630 DOI: 10.1001/Archpsyc.1985.01790260027003  0.389
1985 Breier A, Charney DS, Heninger GR. The diagnostic validity of anxiety disorders and their relationship to depressive illness American Journal of Psychiatry. 142: 787-797. PMID 2861752 DOI: 10.1176/Ajp.142.7.787  0.387
1985 Charney DS, Heninger GR. Noradrenergic Function and the Mechanism of Action of Antianxiety Treatment: I. The Effect of Long-term Alprazolam Treatment Archives of General Psychiatry. 42: 458-467. PMID 2859008 DOI: 10.1001/Archpsyc.1985.01790280040004  0.339
1984 Charney DS, Heninger GR, Breier A. Noradrenergic Function in Panic Anxiety: Effects of Yohimbine in Healthy Subjects and Patients With Agoraphobia and Panic Disorder Archives of General Psychiatry. 41: 751-763. PMID 6742977 DOI: 10.1001/Archpsyc.1984.01790190025003  0.381
1984 Charney DS, Galloway MP, Heninger GR. The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans. Life Sciences. 35: 135-44. PMID 6738307 DOI: 10.1016/0024-3205(84)90132-2  0.313
1984 Heninger GR, Charney DS, Sternberg DE. Serotonergic Function in Depression: Prolactin Response to Intravenous Tryptophan in Depressed Patients and Healthy Subjects Archives of General Psychiatry. 41: 398-402. PMID 6703856 DOI: 10.1001/Archpsyc.1984.01790150088012  0.383
1984 Charney DS, Heninger GR, Sternberg DE. Serotonin Function and Mechanism of Action of Antidepressant Treatment: Effects of Amitriptyline and Desipramine Archives of General Psychiatry. 41: 359-365. PMID 6703855 DOI: 10.1001/Archpsyc.1984.01790150049008  0.343
1984 Price LH, Craig Nelson J, Charney DS, Quinlan DM. The clinical utility of family history for the diagnosis of melancholia Journal of Nervous and Mental Disease. 172: 5-11. PMID 6690653  0.466
1984 Price LH, Charney DS, Heninger GR. Manic symptoms following addition of lithium to antidepressant treatment Journal of Clinical Psychopharmacology. 4: 361-362. PMID 6512008 DOI: 10.1097/00004714-198412000-00020  0.52
1984 Breier A, Charney DS, Heninger GR. Major Depression in Patients With Agoraphobia and Panic Disorder Archives of General Psychiatry. 41: 1129-1135. PMID 6508503 DOI: 10.1001/Archpsyc.1984.01790230015002  0.398
1984 Charney DS, Redmond DE, Galloway MP, Kleber HD, Heninger GR, Murberg M, Roth RH. Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: evidence for noradrenergic hyperactivity. Life Sciences. 35: 1263-72. PMID 6482651 DOI: 10.1016/0024-3205(84)90097-3  0.322
1984 Charney DS, Heninger GR, Sternberg DE. The effect of mianserin on alpha-2 adrenergic receptor function in depressed patients British Journal of Psychiatry. 144: 407-416. PMID 6326924 DOI: 10.1192/Bjp.144.4.407  0.314
1984 Price LH, Nelson JC, Charney DS, Quinlan DM. Family history in delusional depression Journal of Affective Disorders. 6: 109-114. PMID 6231325 DOI: 10.1016/0165-0327(84)90012-0  0.534
1984 Price LH, Charney DS, Heninger GR. Three cases of manic symptoms following yohimbine administration American Journal of Psychiatry. 141: 1267-1268. PMID 6091464 DOI: 10.1176/Ajp.141.10.1267  0.501
1983 Charney DS, Heninger GR, Redmond DE. Yohimbine induced anxiety and increased noradrenergic function in humans: Effects of diazepam and clonidine Life Sciences. 33: 19-29. PMID 6865647 DOI: 10.1016/0024-3205(83)90707-5  0.34
1983 Heninger GR, Charney DS, Sternberg DE. Lithium Carbonate Augmentation of Antidepressant Treatment: An Effective Prescription for Treatment-Refractory Depression Archives of General Psychiatry. 40: 1335-1342. PMID 6418110 DOI: 10.1001/Archpsyc.1983.01790110077013  0.324
1983 Charney DS, Redmond DE. Neurobiological mechanisms in human anxiety evidence supporting central noradrenergic hyperactivity Neuropharmacology. 22: 1531-1536. DOI: 10.1016/0028-3908(83)90122-3  0.356
1983 Heninger GR, Charney DS. Urinary MHPG and Response to Amitriptyline-Reply Archives of General Psychiatry. 40: 467. DOI: 10.1001/Archpsyc.1983.01790040121019  0.328
1982 Charney DS, Riordan CE, Kleber HD, Murburg M, Braverman P, Sternberg DE, Heninger GR, Redmond DE. Clonidine and naltrexone. A safe, effective, and rapid treatment of abrupt withdrawal from methadone therapy. Archives of General Psychiatry. 39: 1327-32. PMID 7138234 DOI: 10.1001/Archpsyc.1982.04290110077013  0.301
1982 Charney DS, Heninger GR, Sternberg DE. Failure of chronic antidepressant treatment to alter growth hormone response to clonidine Psychiatry Research. 7: 135-138. PMID 6959166 DOI: 10.1016/0165-1781(92)90085-H  0.334
1982 Charney DS, Heninger GR, Reinhard JF, Sternberg DE, Hafstead KM. The effect of IV L-tryptophan on prolactin, growth hormone, and mood in healthy subjects. Psychopharmacology. 78: 38-43. PMID 6815695 DOI: 10.1007/Bf00470585  0.307
1982 Charney DS, Heninger GR, Reinhard JF, Sternberg DE, Hafstead KM. The effect of intravenous L-tryptophan on prolactin and growth hormone and mood in healthy subjects. Psychopharmacology. 77: 217-22. PMID 6812143 DOI: 10.1007/Bf00464569  0.307
1982 Charney DS, Heninger GR, Sternberg DE, Landis H. Abrupt discontinuation of tricyclic antidepressant drugs: Evidence for noradrenergic hyperactivity British Journal of Psychiatry. 141: 377-386. PMID 6756531 DOI: 10.1192/Bjp.141.4.377  0.377
1982 Charney DS, Heninger GR, Sternberg DE, Hafstad KM, Giddings S, Landis DH. Adrenergic receptor sensitivity in depression. Effects of clonidine in depressed patients and healthy subjects. Archives of General Psychiatry. 39: 290-4. PMID 6279050 DOI: 10.1001/Archpsyc.1982.04290030030005  0.361
1981 Charney DS, Sternberg DE, Kleber HD, Heninger GR, Redmond DE. The Clinical use of Clonidine in Abrupt Withdrawal from Methadone: Effects on Blood Prennssure and Specific Signs and Symptoms Archives of General Psychiatry. 38: 1273-1277. PMID 7305608 DOI: 10.1001/Archpsyc.1981.01780360089010  0.335
1981 Nelson JC, Charney DS, Quinlan DM. Evaluation of the DSM-III Criteria for Melancholia Archives of General Psychiatry. 38: 555-559. PMID 7235857 DOI: 10.1001/Archpsyc.1980.01780300067008  0.392
1981 Charney DS, Heninger GR, Sternberg DE, Roth RH. Plasma MHPG in depression: effects of acute and chronic desipramine treatment. Psychiatry Research. 5: 217-29. PMID 6945615 DOI: 10.1016/0165-1781(81)90051-2  0.308
1981 Charney DS, Heninger GR, Sternberg DE, Redmond DE, Leckman JF, Maas JW, Roth RH. Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment. Archives of General Psychiatry. 38: 1334-40. PMID 6274268 DOI: 10.1001/Archpsyc.1981.01780370036004  0.345
1981 Charney DS, Menkes DB, Heninger GR. Receptor Sensitivity and the Mechanism of Action of Antidepressant Treatment: Implications for the Etiology and Therapy of Depression Archives of General Psychiatry. 38: 1160-1180. PMID 6271089 DOI: 10.1097/00004714-198204000-00031  0.344
1980 Kales JD, Kales A, Soldatos CR, Caldwell AB, Charney DS, Martin ED. Night terrors. Clinical characteristics and personality patterns. Archives of General Psychiatry. 37: 1413-7. PMID 7447622 DOI: 10.1001/Archpsyc.1980.01780250099012  0.6
1980 Kales A, Soldatos CR, Caldwell AB, Kales JD, Humphrey FJ, Charney DS, Schweitzer PK. Somnambulism. Clinical characteristics and personality patterns. Archives of General Psychiatry. 37: 1406-10. PMID 7447621 DOI: 10.1001/Archpsyc.1980.01780250092011  0.546
1980 Craig Nelson J, Charney DS, Quinlan DM. Characteristics of autonomous depression Journal of Nervous and Mental Disease. 168: 637-643. PMID 7441225 DOI: 10.1097/00005053-198011000-00001  0.38
1980 Kales A, Soldatos CR, Bixler EO, Ladda RL, Charney DS, Weber G, Schweitzer PK. Hereditary factors in sleepwalking and night terrors. The British Journal of Psychiatry : the Journal of Mental Science. 137: 111-8. PMID 7426840 DOI: 10.1192/Bjp.137.2.111  0.523
1980 Kales A, Soldatos CR, Caldwell AB, Charney DS, Kales JD, Markel D, Cadieux R. Nightmares: clinical characteristics and personality patterns. The American Journal of Psychiatry. 137: 1197-201. PMID 7416265 DOI: 10.1176/Ajp.137.10.1197  0.563
1980 Nelson JC, Charney DS. Primary Affective Disorder Criteria and the Endogenous-Reactive Distinction Archives of General Psychiatry. 37: 787-793. PMID 7396656 DOI: 10.1001/Archpsyc.1980.01780200065007  0.421
1979 Charney DS, Kales A, Soldatos CR, Nelson JC. Somnambulistic-like episodes secondary to combined lithium-neuroleptic treatment British Journal of Psychiatry. 135: 418-424. PMID 44211 DOI: 10.1192/Bjp.135.5.418  0.543
Low-probability matches (unlikely to be authored by this person)
1985 Kleber HD, Riordan CE, Rounsaville B, Kosten T, Charney D, Gaspari J, Hogan I, O'Connor C. Clonidine in outpatient detoxification from methadone maintenance. Archives of General Psychiatry. 42: 391-4. PMID 3977557 DOI: 10.1001/Archpsyc.1985.01790270081009  0.3
1986 Matthews J, Akil H, Greden J, Charney D, Weinberg V, Rosenbaum A, Watson SJ. beta-Endorphin/beta-lipotropin immunoreactivity in endogenous depression. Effect of dexamethasone. Archives of General Psychiatry. 43: 374-81. PMID 2937385 DOI: 10.1001/Archpsyc.1986.01800040084012  0.298
1997 Johnson DR, Lubin H, Rosenheck R, Fontana A, Southwick S, Charney D. The impact of the homecoming reception on the development of posttraumatic stress disorder. The West Haven Homecoming Stress Scale (WHHSS). Journal of Traumatic Stress. 10: 259-77. PMID 9136091 DOI: 10.1023/A:1024830229391  0.298
2005 Bremner JD, Vermetten E, Schmahl C, Vaccarino V, Vythilingam M, Afzal N, Grillon C, Charney DS. Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder. Psychological Medicine. 35: 791-806. PMID 15997600 DOI: 10.1017/S0033291704003290  0.297
2016 Horn SR, Charney DS, Feder A. Understanding resilience: New approaches for preventing and treating PTSD. Experimental Neurology. PMID 27417856 DOI: 10.1016/J.Expneurol.2016.07.002  0.297
2017 Murrough JW, Charney DS. Corticotropin-Releasing Factor Type 1 Receptor Antagonists for Stress-Related Disorders: Time to Call It Quits? Biological Psychiatry. 82: 858-860. PMID 29129198 DOI: 10.1016/J.Biopsych.2017.10.012  0.297
2014 Iacoviello BM, Charney DS. Psychosocial facets of resilience: implications for preventing posttrauma psychopathology, treating trauma survivors, and enhancing community resilience. European Journal of Psychotraumatology. 5. PMID 25317258 DOI: 10.3402/Ejpt.V5.23970  0.296
1994 Johnson DR, Feldman SC, Southwick SM, Charney DS. The concept of the second generation program in the treatment of post-traumatic stress disorder among vietnam veterans Journal of Traumatic Stress. 7: 217-235. PMID 8012744 DOI: 10.1007/Bf02102945  0.296
1982 Sternberg DE, Charney DS, Heninger GR, Leckman JF, Hafstad KM, Landis DH. Impaired presynaptic regulation of norepinephrine in schizophrenia. Effects of clonidine in schizophrenic patients and normal controls. Archives of General Psychiatry. 39: 285-9. PMID 6279049 DOI: 10.1001/Archpsyc.1982.04290030025004  0.295
2015 Iacoviello BM, Charney DS. Developing cognitive-emotional training exercises as interventions for mood and anxiety disorders. European Psychiatry : the Journal of the Association of European Psychiatrists. 30: 75-81. PMID 25451246 DOI: 10.1016/J.Eurpsy.2014.09.415  0.295
2003 Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Staib LH, Soufer R, Charney DS. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biological Psychiatry. 53: 879-89. PMID 12742675 DOI: 10.1016/S0006-3223(02)01891-7  0.295
2020 Mathé AA, Michaneck M, Berg E, Charney DS, Murrough JW. A Randomized Controlled Trial of Intranasal Neuropeptide Y in Patients With Major Depressive Disorder. The International Journal of Neuropsychopharmacology. PMID 33009815 DOI: 10.1093/ijnp/pyaa054  0.294
2008 Stellman JM, Smith RP, Katz CL, Sharma V, Charney DS, Herbert R, Moline J, Luft BJ, Markowitz S, Udasin I, Harrison D, Baron S, Landrigan PJ, Levin SM, Southwick S. Enduring mental health morbidity and social function impairment in world trade center rescue, recovery, and cleanup workers: the psychological dimension of an environmental health disaster. Environmental Health Perspectives. 116: 1248-53. PMID 18795171 DOI: 10.1289/Ehp.11164  0.294
2004 Southwick SM, Charney DS. Responses to trauma: Normal reactions or pathological symptoms Psychiatry. 67: 170-173. PMID 15262585 DOI: 10.1521/Psyc.67.2.170.35960  0.294
2009 Haglund ME, aan het Rot M, Cooper NS, Nestadt PS, Muller D, Southwick SM, Charney DS. Resilience in the third year of medical school: a prospective study of the associations between stressful events occurring during clinical rotations and student well-being. Academic Medicine : Journal of the Association of American Medical Colleges. 84: 258-68. PMID 19174682 DOI: 10.1097/Acm.0B013E31819381B1  0.294
2022 Evers AG, Murrough JW, Charney DS, Costi S. Ketamine as a prophylactic resilience-enhancing agent. Frontiers in Psychiatry. 13: 833259. PMID 35966469 DOI: 10.3389/fpsyt.2022.833259  0.294
2014 Lekman M, Hössjer O, Andrews P, Källberg H, Uvehag D, Charney D, Manji H, Rush JA, McMahon FJ, Moore JH, Kockum I. The genetic interacting landscape of 63 candidate genes in Major Depressive Disorder: an explorative study. Biodata Mining. 7: 19. PMID 25279001 DOI: 10.1186/1756-0381-7-19  0.294
2003 Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Nazeer A, Khan S, Vaccarino LV, Soufer R, Garg PK, Ng CK, Staib LH, Duncan JS, Charney DS. MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder. The American Journal of Psychiatry. 160: 924-32. PMID 12727697 DOI: 10.1176/Appi.Ajp.160.5.924  0.294
2008 Alim TN, Feder A, Graves RE, Wang Y, Weaver J, Westphal M, Alonso A, Aigbogun NU, Smith BW, Doucette JT, Mellman TA, Lawson WB, Charney DS. Trauma, resilience, and recovery in a high-risk African-American population. The American Journal of Psychiatry. 165: 1566-75. PMID 19015233 DOI: 10.1176/Appi.Ajp.2008.07121939  0.293
2007 Paddock S, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ. Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort. The American Journal of Psychiatry. 164: 1181-8. PMID 17671280 DOI: 10.1176/Appi.Ajp.2007.06111790  0.293
2004 Neumeister A, Bain E, Nugent AC, Carson RE, Bonne O, Luckenbaugh DA, Eckelman W, Herscovitch P, Charney DS, Drevets WC. Reduced serotonin type 1A receptor binding in panic disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 589-91. PMID 14736842 DOI: 10.1523/Jneurosci.4921-03.2004  0.293
1983 Charney DS, Heninger GR, Sternberg DE. Alpha-2-adrenergic receptor sensitivity and the mechanism of action of antidepressant therapy. The effect of long-term amitriptyline treatment British Journal of Psychiatry. 142: 265-275. PMID 6305451 DOI: 10.1192/Bjp.142.3.265  0.292
2007 Zarate CA, Charney DS, Manji HK. Searching for rational anti-N-methyl-D-aspartate treatment for depression: Reply [6] Archives of General Psychiatry. 64: 1100-1101. DOI: 10.1001/Archpsyc.64.9.1100  0.292
2003 Bremner JD, Vythilingam M, Anderson G, Vermetten E, McGlashan T, Heninger G, Rasmusson A, Southwick SM, Charney DS. Assessment of the hypothalamic-pituitary-adrenal axis over a 24-hour diurnal period and in response to neuroendocrine challenges in women with and without childhood sexual abuse and posttraumatic stress disorder. Biological Psychiatry. 54: 710-8. PMID 14512211 DOI: 10.1016/S0006-3223(02)01912-1  0.29
1996 Mason JW, Weizman R, Laor N, Wang S, Schujovitsky A, Abramovitz-Schneider P, Feiler D, Charney D. Serum triiodothyronine elevation in Israeli combat veterans with posttraumatic stress disorder: A cross-cultural study Biological Psychiatry. 39: 835-838. PMID 9172703 DOI: 10.1016/0006-3223(95)00310-X  0.29
2000 Charney DS. The use of placebos in randomized clinical trials of mood disorders: Well justified, but improvements in design are indicated Biological Psychiatry. 47: 687-688. PMID 10773172 DOI: 10.1016/S0006-3223(00)00845-3  0.289
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