Gene E. Alexander - Publications

Affiliations: 
Neuroscience University of Arizona, Tucson, AZ 
Area:
Neuroscience Biology, Aging, Radiology

168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lopez FV, O'Shea A, Huo Z, DeKosky ST, Trouard TP, Alexander GE, Woods AJ, Bowers D. Frontal-temporal regional differences in brain energy metabolism and mitochondrial function using P MRS in older adults. Geroscience. PMID 38225480 DOI: 10.1007/s11357-023-01046-3  0.302
2022 Song H, Bharadwaj PK, Raichlen DA, Habeck CG, Huentelman MJ, Hishaw GA, Trouard TP, Alexander GE. Association of homocysteine-related subcortical brain atrophy with white matter lesion volume and cognition in healthy aging. Neurobiology of Aging. 121: 129-138. PMID 36436304 DOI: 10.1016/j.neurobiolaging.2022.10.011  0.352
2021 Boutzoukas EM, O'Shea A, Albizu A, Evangelista ND, Hausman HK, Kraft JN, Van Etten EJ, Bharadwaj PK, Smith SG, Song H, Porges EC, Hishaw A, DeKosky ST, Wu SS, Marsiske M, ... Alexander GE, et al. Frontal White Matter Hyperintensities and Executive Functioning Performance in Older Adults. Frontiers in Aging Neuroscience. 13: 672535. PMID 34262445 DOI: 10.3389/fnagi.2021.672535  0.325
2021 Van Etten EJ, Bharadwaj PK, Hishaw GA, Huentelman MJ, Trouard TP, Grilli MD, Alexander GE. Influence of regional white matter hyperintensity volume and apolipoprotein E ε4 status on hippocampal volume in healthy older adults. Hippocampus. PMID 33586848 DOI: 10.1002/hipo.23308  0.31
2020 Kraft JN, O'Shea A, Albizu A, Evangelista ND, Hausman HK, Boutzoukas E, Nissim NR, Van Etten EJ, Bharadwaj PK, Song H, Smith SG, Porges E, DeKosky S, Hishaw GA, Wu S, ... ... Alexander GE, et al. Structural Neural Correlates of Double Decision Performance in Older Adults. Frontiers in Aging Neuroscience. 12: 278. PMID 33117145 DOI: 10.3389/Fnagi.2020.00278  0.373
2020 Alexander GE, Lin L, Yoshimaru ES, Bharadwaj PK, Bergfield KL, Hoang LT, Chawla MK, Chen K, Moeller JR, Barnes CA, Trouard TP. Age-Related Regional Network Covariance of Magnetic Resonance Imaging Gray Matter in the Rat. Frontiers in Aging Neuroscience. 12: 267. PMID 33005147 DOI: 10.3389/Fnagi.2020.00267  0.402
2020 Van Etten EJ, Bharadwaj PK, Nguyen LA, Hishaw GA, Trouard TP, Alexander GE. Right hippocampal volume mediation of subjective memory complaints differs by hypertension status in healthy aging. Neurobiology of Aging. 94: 271-280. PMID 32688134 DOI: 10.1016/J.Neurobiolaging.2020.06.012  0.403
2020 Hausman HK, O'Shea A, Kraft JN, Boutzoukas EM, Evangelista ND, Van Etten EJ, Bharadwaj PK, Smith SG, Porges E, Hishaw GA, Wu S, DeKosky S, Alexander GE, Marsiske M, Cohen R, et al. The Role of Resting-State Network Functional Connectivity in Cognitive Aging. Frontiers in Aging Neuroscience. 12: 177. PMID 32595490 DOI: 10.3389/Fnagi.2020.00177  0.414
2020 Raichlen DA, Bharadwaj PK, Nguyen LA, Franchetti MK, Zigman EK, Solorio AR, Alexander GE. Effects of simultaneous cognitive and aerobic exercise training on dual-task walking performance in healthy older adults: results from a pilot randomized controlled trial. Bmc Geriatrics. 20: 83. PMID 32122325 DOI: 10.1186/S12877-020-1484-5  0.304
2019 Raichlen DA, Klimentidis YC, Bharadwaj PK, Alexander GE. Differential associations of engagement in physical activity and estimated cardiorespiratory fitness with brain volume in middle-aged to older adults. Brain Imaging and Behavior. PMID 31209836 DOI: 10.1007/S11682-019-00148-X  0.323
2018 Stonnington CM, Chen Y, Savage CR, Lee W, Bauer Iii RJ, Sharieff S, Thiyyagura P, Alexander GE, Caselli RJ, Locke DEC, Reiman EM, Chen K. Predicting Imminent Progression to Clinically Significant Memory Decline Using Volumetric MRI and FDG PET. Journal of Alzheimer's Disease : Jad. PMID 29630550 DOI: 10.3233/Jad-170852  0.414
2017 Woods AJ, Cohen R, Marsiske M, Alexander GE, Czaja SJ, Wu S. Augmenting cognitive training in older adults (The ACT Study): Design and Methods of a Phase III tDCS and cognitive training trial. Contemporary Clinical Trials. PMID 29313802 DOI: 10.1016/J.Cct.2017.11.017  0.352
2017 Cohen RA, Alexander GE. Using the Telephone Interview for Cognitive Status and Telephone Montreal Cognitive Assessment for Evaluating Vascular Cognitive Impairment: Promising Call or Put on Hold? Stroke. PMID 29042491 DOI: 10.1161/Strokeaha.117.018828  0.378
2017 Raichlen DA, Alexander GE. Adaptive Capacity: An Evolutionary Neuroscience Model Linking Exercise, Cognition, and Brain Health. Trends in Neurosciences. PMID 28610948 DOI: 10.1016/J.Tins.2017.05.001  0.352
2017 Kern KC, Wright CB, Bergfield KL, Fitzhugh MC, Chen K, Moeller JR, Nabizadeh N, Elkind MSV, Sacco RL, Stern Y, DeCarli CS, Alexander GE. Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions. Frontiers in Aging Neuroscience. 9: 132. PMID 28555103 DOI: 10.3389/Fnagi.2017.00132  0.393
2016 Raichlen DA, Bharadwaj PK, Fitzhugh MC, Haws KA, Torre GA, Trouard TP, Alexander GE. Differences in Resting State Functional Connectivity between Young Adult Endurance Athletes and Healthy Controls. Frontiers in Human Neuroscience. 10: 610. PMID 28018192 DOI: 10.3389/Fnhum.2016.00610  0.374
2016 Alexander GE. An Emerging Role for Imaging White Matter in the Preclinical Risk for Alzheimer Disease: Linking β-Amyloid to Myelin. Jama Neurology. PMID 27842149 DOI: 10.1001/Jamaneurol.2016.4123  0.331
2014 Raichlen DA, Alexander GE. Exercise, APOE genotype, and the evolution of the human lifespan. Trends in Neurosciences. 37: 247-55. PMID 24690272 DOI: 10.1016/J.Tins.2014.03.001  0.39
2013 Smith JF, Braun AR, Alexander GE, Chen K, Horwitz B. Separating lexical-semantic access from other mnemonic processes in picture-name verification. Frontiers in Psychology. 4: 706. PMID 24130539 DOI: 10.3389/Fpsyg.2013.00706  0.323
2013 Schraml F, Chen K, Ayutyanont N, Auttawut R, Langbaum JB, Lee W, Liu X, Bandy D, Reeder SQ, Alexander GE, Caselli RJ, Fleisher AS, Reiman EM. Association between an Alzheimer's Disease-Related Index and APOE ε4 Gene Dose. Plos One. 8: e67163. PMID 23840615 DOI: 10.1371/Journal.Pone.0067163  0.423
2013 Protas HD, Chen K, Langbaum JB, Fleisher AS, Alexander GE, Lee W, Bandy D, de Leon MJ, Mosconi L, Buckley S, Truran-Sacrey D, Schuff N, Weiner MW, Caselli RJ, Reiman EM. Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease. Jama Neurology. 70: 320-5. PMID 23599929 DOI: 10.1001/2013.Jamaneurol.286  0.404
2013 Burns CM, Chen K, Kaszniak AW, Lee W, Alexander GE, Bandy D, Fleisher AS, Caselli RJ, Reiman EM. Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions. Neurology. 80: 1557-64. PMID 23535495 DOI: 10.1212/Wnl.0B013E31828F17De  0.412
2012 Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, ... ... Alexander GE, et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. The Lancet. Neurology. 11: 1048-56. PMID 23137948 DOI: 10.1016/S1474-4422(12)70228-4  0.473
2012 Alexander GE, Ryan L, Bowers D, Foster TC, Bizon JL, Geldmacher DS, Glisky EL. Characterizing cognitive aging in humans with links to animal models. Frontiers in Aging Neuroscience. 4: 21. PMID 22988439 DOI: 10.3389/Fnagi.2012.00021  0.381
2012 Bizon JL, Foster TC, Alexander GE, Glisky EL. Characterizing cognitive aging of working memory and executive function in animal models. Frontiers in Aging Neuroscience. 4: 19. PMID 22988438 DOI: 10.3389/Fnagi.2012.00019  0.354
2012 Roberson ED, Defazio RA, Barnes CA, Alexander GE, Bizon JL, Bowers D, Foster TC, Glisky EL, Levin BE, Ryan L, Wright CB, Geldmacher DS. Challenges and opportunities for characterizing cognitive aging across species. Frontiers in Aging Neuroscience. 4: 6. PMID 22988434 DOI: 10.3389/Fnagi.2012.00006  0.395
2012 Alexander GE, Bergfield KL, Chen K, Reiman EM, Hanson KD, Lin L, Bandy D, Caselli RJ, Moeller JR. Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults. Neurobiology of Aging. 33: 2723-32. PMID 22405043 DOI: 10.1016/J.Neurobiolaging.2012.01.014  0.789
2012 Chen K, Ayutyanont N, Langbaum JB, Fleisher AS, Reschke C, Lee W, Liu X, Alexander GE, Bandy D, Caselli RJ, Reiman EM. Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E ε4 gene dose in cognitively normal adults: a cross-validation study using voxel-based multi-modal partial least squares. Neuroimage. 60: 2316-22. PMID 22348880 DOI: 10.1016/J.Neuroimage.2012.02.005  0.424
2012 Ewers M, Walsh C, Trojanowski JQ, Shaw LM, Petersen RC, Jack CR, Feldman HH, Bokde AL, Alexander GE, Scheltens P, Vellas B, Dubois B, Weiner M, Hampel H. Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance. Neurobiology of Aging. 33: 1203-14. PMID 21159408 DOI: 10.1016/J.Neurobiolaging.2010.10.019  0.408
2011 Hua X, Gutman B, Boyle CP, Rajagopalan P, Leow AD, Yanovsky I, Kumar AR, Toga AW, Jack CR, Schuff N, Alexander GE, Chen K, Reiman EM, Weiner MW, Thompson PM, et al. Accurate measurement of brain changes in longitudinal MRI scans using tensor-based morphometry. Neuroimage. 57: 5-14. PMID 21320612 DOI: 10.1016/J.Neuroimage.2011.01.079  0.322
2011 Chen K, Ayutyanont N, Langbaum JB, Fleisher AS, Reschke C, Lee W, Liu X, Bandy D, Alexander GE, Thompson PM, Shaw L, Trojanowski JQ, Jack CR, Landau SM, Foster NL, et al. Characterizing Alzheimer's disease using a hypometabolic convergence index. Neuroimage. 56: 52-60. PMID 21276856 DOI: 10.1016/J.Neuroimage.2011.01.049  0.464
2011 Burns C, Chen K, Kaszniak A, Lee W, Alexander G, Bandy D, Fleisher A, Caselli R, Reiman E. Investigating the association between fasting serum glucose levels and cerebral metabolic rate for glucose in brain regions affected by Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.152  0.364
2011 Ayutyanont N, Chen K, Roontiva A, Fleisher A, Langbaum J, Reschke C, Lee W, Liu X, Bandy D, Alexander G, Foster N, Harvey D, Weiner M, Koeppe R, Jagust W, et al. Use of an FDG-PET derived hypometabolic convergence index enrichment strategy to reduce sample sizes in Alzheimer's disease clinical trials: findings from the Alzheimer's Disease Neuroimaging Initiative (ADNI) Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.150  0.393
2010 Wu X, Chen K, Yao L, Ayutyanont N, Langbaum JB, Fleisher A, Reschke C, Lee W, Liu X, Alexander GE, Bandy D, Foster NL, Thompson PM, Harvey DJ, Weiner MW, et al. Assessing the reliability to detect cerebral hypometabolism in probable Alzheimer's disease and amnestic mild cognitive impairment. Journal of Neuroscience Methods. 192: 277-85. PMID 20678521 DOI: 10.1016/J.Jneumeth.2010.07.030  0.447
2010 Langbaum JB, Chen K, Caselli RJ, Lee W, Reschke C, Bandy D, Alexander GE, Burns CM, Kaszniak AW, Reeder SA, Corneveaux JJ, Allen AN, Pruzin J, Huentelman MJ, Fleisher AS, et al. Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele. Archives of Neurology. 67: 462-8. PMID 20385913 DOI: 10.1001/Archneurol.2010.30  0.44
2010 Chen K, Langbaum JB, Fleisher AS, Ayutyanont N, Reschke C, Lee W, Liu X, Bandy D, Alexander GE, Thompson PM, Foster NL, Harvey DJ, de Leon MJ, Koeppe RA, Jagust WJ, et al. Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative. Neuroimage. 51: 654-64. PMID 20202480 DOI: 10.1016/J.Neuroimage.2010.02.064  0.48
2010 Hua X, Lee S, Hibar DP, Yanovsky I, Leow AD, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM, et al. Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals. Neuroimage. 51: 63-75. PMID 20139010 DOI: 10.1016/J.Neuroimage.2010.01.104  0.415
2010 Bergfield KL, Hanson KD, Chen K, Teipel SJ, Hampel H, Rapoport SI, Moeller JR, Alexander GE. Age-related networks of regional covariance in MRI gray matter: reproducible multivariate patterns in healthy aging. Neuroimage. 49: 1750-9. PMID 19796692 DOI: 10.1016/J.Neuroimage.2009.09.051  0.746
2010 Ho AJ, Hua X, Lee S, Leow AD, Yanovsky I, Gutman B, Dinov ID, Leporé N, Stein JL, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, ... ... Alexander GE, et al. Comparing 3 T and 1.5 T MRI for tracking Alzheimer's disease progression with tensor-based morphometry. Human Brain Mapping. 31: 499-514. PMID 19780044 DOI: 10.1002/Hbm.20882  0.433
2010 Reiman EM, Chen K, Langbaum JB, Lee W, Reschke C, Bandy D, Alexander GE, Caselli RJ. Higher serum total cholesterol levels in late middle age are associated with glucose hypometabolism in brain regions affected by Alzheimer's disease and normal aging. Neuroimage. 49: 169-76. PMID 19631758 DOI: 10.1016/J.Neuroimage.2009.07.025  0.455
2010 Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, ... ... Alexander GE, et al. Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiology of Aging. 31: 901-9. PMID 18789830 DOI: 10.1016/J.Neurobiolaging.2008.07.014  0.449
2010 Chen K, Ayutyanont N, Langbaum J, Fleisher A, Reschke C, Lee W, Liu X, Alexander GE, Bandy D, Yu M, Foster NL, Weiner MW, Thompson PM, Koeppe RA, Jagust WJ, et al. Use of an Alzheimer's Disease-Related Hypometabolic Convergence Index to Predict Progression from Mild Cognitive Impairment to Alzheimer's Dementia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.971  0.46
2010 Alexander GE. Networks of regional covariance in MRI gray matter: Reproducible multivariate patterns in Alzheimer's disease, mild cognitive impairment and healthy aging Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.523  0.501
2010 Reiman EM, Chen K, Dueck AC, Fleisher AS, Langbaum JB, Ayutyanont N, Reschke C, Liu X, Bandy D, Reeder SA, Henslin BR, Yee-Benedetto SC, Tariot PN, Keppler J, Alexander GE, et al. O3-06-08: Sample size estimates for pre-symptomatic Alzheimer's disease treatment/surrogate marker development trials in Apolipoprotein E4 homozygotes close to their estimated age at symptomatic onset Alzheimer's & Dementia. 6: S141-S141. DOI: 10.1016/J.Jalz.2010.05.434  0.325
2010 Fleisher AS, Chen K, Ayutyanont N, Roontiva A, Langbaum JBS, Lee W, Liu X, Bandy D, Reeder S, Alexander GE, Caselli RJ, Reiman EM. Association Between an Alzheimer's Disease-Related Hypometabolic Convergence Index in Cognitively Normal Late-Middle-Aged People and Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.137  0.464
2010 Fleisher AS, Chen K, Liu X, Ayutyanont N, Langbaum JB, Lee W, Reeder SA, Alexander GE, Bandy D, Caselli RJ, Reiman EM. IC-02-01: Association between cerebral patterns of fibrillar beta-amyloid burden and glucose hypometabolism in cognitively normal older adults at three levels of genetic risk for late-onset Alzheimer's disease Alzheimer's & Dementia. 6: S4-S4. DOI: 10.1016/J.Jalz.2010.05.011  0.401
2009 Hua X, Lee S, Yanovsky I, Leow AD, Chou YY, Ho AJ, Gutman B, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, et al. Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects. Neuroimage. 48: 668-81. PMID 19615450 DOI: 10.1016/J.Neuroimage.2009.07.011  0.448
2009 Caselli RJ, Dueck AC, Osborne D, Sabbagh MN, Connor DJ, Ahern GL, Baxter LC, Rapcsak SZ, Shi J, Woodruff BK, Locke DE, Snyder CH, Alexander GE, Rademakers R, Reiman EM. Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect. The New England Journal of Medicine. 361: 255-63. PMID 19605830 DOI: 10.1056/Nejmoa0809437  0.379
2009 Chen K, Reiman EM, Huan Z, Caselli RJ, Bandy D, Ayutyanont N, Alexander GE. Linking functional and structural brain images with multivariate network analyses: a novel application of the partial least square method. Neuroimage. 47: 602-10. PMID 19393744 DOI: 10.1016/J.Neuroimage.2009.04.053  0.334
2009 Langbaum JB, Chen K, Lee W, Reschke C, Bandy D, Fleisher AS, Alexander GE, Foster NL, Weiner MW, Koeppe RA, Jagust WJ, Reiman EM. Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Neuroimage. 45: 1107-16. PMID 19349228 DOI: 10.1016/J.Neuroimage.2008.12.072  0.486
2009 Reiman EM, Chen K, Liu X, Bandy D, Yu M, Lee W, Ayutyanont N, Keppler J, Reeder SA, Langbaum JB, Alexander GE, Klunk WE, Mathis CA, Price JC, Aizenstein HJ, et al. Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 6820-5. PMID 19346482 DOI: 10.1073/Pnas.0900345106  0.463
2009 Leow AD, Yanovsky I, Parikshak N, Hua X, Lee S, Toga AW, Jack CR, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Borowski B, Shaw LM, Trojanowski JQ, Fleisher AS, ... ... Alexander GE, et al. Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition. Neuroimage. 45: 645-55. PMID 19280686 DOI: 10.1016/J.Neuroimage.2009.01.004  0.494
2009 Ewers M, Walsh C, Trojanowski JQ, Shaw LM, Sheltens P, Bokde AL, Feldman H, Alexander GE, Dubois B, Hampel H. P4-332: Biomarker Based Diagnosis Of Very Mild Alzheimer's Disease: A Multicenter Study Alzheimer's & Dementia. 5: e28-e28. DOI: 10.1016/J.Jalz.2009.07.111  0.391
2009 Wagner M, Meindl T, Alexander G, Hennig-Fast K, Bürger K, Benninghoff J, Engel R, Reiser MF, Möller HJ, Hampel H, Teipel SJ. Subcortical fiber tract integrity and the CERAD cognitive battery in patients with Alzheimer's disease: A multivariate approach to detect morphological correlates of cognitive failure Alzheimers & Dementia. 5: 268. DOI: 10.1016/J.Jalz.2009.04.334  0.388
2008 Caselli RJ, Chen K, Lee W, Alexander GE, Reiman EM. Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment. Archives of Neurology. 65: 1231-6. PMID 18779428 DOI: 10.1001/Archneurol.2008.1  0.388
2008 Hua X, Leow AD, Lee S, Klunder AD, Toga AW, Lepore N, Chou YY, Brun C, Chiang MC, Barysheva M, Jack CR, Bernstein MA, Britson PJ, Ward CP, Whitwell JL, ... ... Alexander GE, et al. 3D characterization of brain atrophy in Alzheimer's disease and mild cognitive impairment using tensor-based morphometry. Neuroimage. 41: 19-34. PMID 18378167 DOI: 10.1016/J.Neuroimage.2008.02.010  0.489
2008 Alexander GE, Chen K, Aschenbrenner M, Merkley TL, Santerre-Lemmon LE, Shamy JL, Skaggs WE, Buonocore MH, Rapp PR, Barnes CA. Age-related regional network of magnetic resonance imaging gray matter in the rhesus macaque. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2710-8. PMID 18337400 DOI: 10.1523/Jneurosci.1852-07.2008  0.467
2008 Jack CR, Bernstein MA, Fox NC, Thompson P, Alexander G, Harvey D, Borowski B, Britson PJ, L Whitwell J, Ward C, Dale AM, Felmlee JP, Gunter JL, Hill DL, Killiany R, et al. The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods. Journal of Magnetic Resonance Imaging : Jmri. 27: 685-91. PMID 18302232 DOI: 10.1002/Jmri.21049  0.395
2008 Reiman EM, Chen K, Caselli RJ, Alexander GE, Bandy D, Adamson JL, Lee W, Cannon A, Stephan EA, Stephan DA, Papassotiropoulos A. Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions. Neuroimage. 40: 1214-21. PMID 18280754 DOI: 10.1016/J.Neuroimage.2007.12.066  0.433
2008 Boyes RG, Gunter JL, Frost C, Janke AL, Yeatman T, Hill DL, Bernstein MA, Thompson PM, Weiner MW, Schuff N, Alexander GE, Killiany RJ, DeCarli C, Jack CR, Fox NC, et al. Intensity non-uniformity correction using N3 on 3-T scanners with multichannel phased array coils. Neuroimage. 39: 1752-62. PMID 18063391 DOI: 10.1016/J.Neuroimage.2007.10.026  0.337
2008 Chen K, Lee W, Liu X, Alexander G, Bandy D, Reschke C, Foster N, Weiner M, Koeppe R, Jagust W, Reiman E. P1-338: The consistency of hypometabolic brain voxels in probable Alzheimer's disease and amnestic mild cognitive impairment patients from the Alzheimer's disease neuroimaging initiative Alzheimer's & Dementia. 4: T318-T318. DOI: 10.1016/J.Jalz.2008.05.919  0.487
2008 Ayutyanont N, Chen K, Liu X, Reschke C, Lee W, Bandy D, Alexander GE, Jagust WJ, Koeppe RA, Foster NL, Reiman EM. P1-312: Differentiating amnestic mild cognitive impairment converting to probable Alzheimer's disease from stable amnestic mild cognitive impairment using FDG-PET and an Alzheimer's disease-related hypometabolism overlap index Alzheimer's & Dementia. 4: T312-T312. DOI: 10.1016/J.Jalz.2008.05.903  0.46
2008 Zhang H, Wu T, Bae M, Reiman EM, Alexander GE, Thompson PM, Jack CR, Chen K. P1-311: Use of the support vector machine and sensitivity of an Alzheimer's disease-related region-of-interest gray matter classifier in identifying amnestic mild cognitive impairment subjects who convert to Alzheimer's disease: Preliminary findings from the Alzheimer's disease neuroimaging initiative Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.902  0.47
2008 Alexander GE, Hanson KD, Chen K, Reiman EM, Bernstein MA, Kornak J, Schuff NW, Fox NC, Thompson PM, Weiner MW, Jack CR. P1-216: Six month MRI gray matter declines in Alzheimer's dementia evaluated by voxel-based morphometry with multivariate network analysis: Preliminary findings from the Alzheimer's Disease Neuroimaging Initiative Alzheimer's & Dementia. 4: T273-T273. DOI: 10.1016/J.Jalz.2008.05.805  0.769
2008 Langbaum JBS, Reiman EM, Chen K, Alexander GE, Bandy D, Smilovici O, Lee W, Recshke C, Caselli RJ. P1-259: Regional hypometabolism in cognitively normal Hispanic carriers of the apolipoprotein E-ϵ4 allele Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2566  0.365
2008 Reiman EM, Chen K, Ayutyanont N, Lee W, Bandy D, Reschke C, Alexander GE, Weiner MW, Koeppe RA, Foster NL, Jagust WJ. O1-02-06: Twelve-month cerebral metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment: Preliminary findings from the Alzheimer's disease neuroimaging initiative (ADNI) Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.225  0.364
2008 Ayutyanont N, Chen K, Liu X, Reschke C, Lee W, Bandy D, Alexander GE, Jagust WJ, Koeppe RA, Foster NL, Reiman EM. IC-P2-074: Differentiating amnestic MCI converting to probable AD from stable amnestic MCI using FDG-PET and an AD-related hypometabolism overlap index Alzheimer's & Dementia. 4: T38-T38. DOI: 10.1016/J.Jalz.2008.05.067  0.373
2008 Lee W, Langbaum JBS, Chen K, Recshke C, Bandy D, Alexander GE, Foster NL, Weiner MW, Koeppe RA, Jagust WJ, Reiman EM. IC-P1-036: Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's disease neuroimaging initiative Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.047  0.379
2008 Alexander GE, Hanson KD, Chen K, Reiman EM, Bernstein MA, Kornak J, Schuff NW, Fox NC, Thompson PM, Weiner MW, Jack CR. IC-03-06: Six month MRI gray matter declines in Alzheimer's dementia evaluated by voxel-based morphometry with multivariate network analysis: Preliminary findings from the ADNI study Alzheimer's & Dementia. 4: T8-T8. DOI: 10.1016/J.Jalz.2008.05.011  0.748
2007 Caselli RJ, Reiman EM, Locke DE, Hutton ML, Hentz JG, Hoffman-Snyder C, Woodruff BK, Alexander GE, Osborne D. Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment. Archives of Neurology. 64: 1306-11. PMID 17846270 DOI: 10.1001/Archneur.64.9.1306  0.427
2007 Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, ... ... Alexander GE, et al. GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron. 54: 713-20. PMID 17553421 DOI: 10.1016/J.Neuron.2007.05.022  0.31
2007 Chen K, Reiman EM, Alexander GE, Caselli RJ, Gerkin R, Bandy D, Domb A, Osborne D, Fox N, Crum WR, Saunders AM, Hardy J. Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates. The American Journal of Psychiatry. 164: 916-21. PMID 17541051 DOI: 10.1176/Ajp.2007.164.6.916  0.466
2007 Etnier JL, Caselli RJ, Reiman EM, Alexander GE, Sibley BA, Tessier D, McLemore EC. Cognitive performance in older women relative to ApoE-epsilon4 genotype and aerobic fitness. Medicine and Science in Sports and Exercise. 39: 199-207. PMID 17218903 DOI: 10.1249/01.Mss.0000239399.85955.5E  0.373
2007 Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Walker DG, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette C, Schmechel D, Alexander GE, Reiman EM, Rogers J, et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiological Genomics. 28: 311-22. PMID 17077275 DOI: 10.1152/Physiolgenomics.00208.2006  0.43
2007 Chen K, Reiman EM, Alexander GE, Smilovici O, Lee W, Reschke C, Bandy D, Foster NL, Weiner MW, Koeppe RA, Jagust WJ. P-024: The pattern and severity of FDG pet abnormalities in Alzheimer’s disease and amnestic mild cognitive impairment: Preliminary findings from the Alzheimer’s disease neuroimaging initiative Alzheimers & Dementia. 3. DOI: 10.1016/J.Jalz.2007.04.240  0.421
2007 Alexander GE, Chen K, Reiman EM, Aschenbrenner M, Merkley TL, Hanson KD, Dale AM, Bernstein MA, Kornak J, Schuff N, Fox NC, Thompson PM, Weiner MW, Jack CR. P-020: Regional gray matter reductions in Alzheimer’s dementia and amnestic mild cognitive impairment: Preliminary findings from the Alzheimer’s disease neuroimaging initiative using voxel-based morphometry Alzheimers & Dementia. 3. DOI: 10.1016/J.Jalz.2007.04.236  0.766
2007 Reiman EM, Chen K, Alexander GE, Reschke C, Lee W, Smilovici O, Buckley S, Sacrey DT, Schuff N, Muller S, Weiner MW, Caselli RJ. O1-05-03: PET measurements of posterior cingulate glucose metabolism are superior to MRI measurements of hippocampal volume in distinguishing cognitively normal persons at differential genetic risk for Alzheimer’s disease Alzheimers & Dementia. 3. DOI: 10.1016/J.Jalz.2007.04.070  0.379
2006 Valla J, Schneider L, Niedzielko T, Coon KD, Caselli R, Sabbagh MN, Ahern GL, Baxter L, Alexander G, Walker DG, Reiman EM. Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment. Mitochondrion. 6: 323-30. PMID 17123871 DOI: 10.1016/J.Mito.2006.10.004  0.427
2006 Caselli RJ, Chen K, Bandy D, Smilovici O, Boeve BF, Osborne D, Alexander GE, Parish JM, Krahn LE, Reiman EM. A preliminary fluorodeoxyglucose positron emission tomography study in healthy adults reporting dream-enactment behavior. Sleep. 29: 927-33. PMID 16895260 DOI: 10.1093/Sleep/29.7.927  0.332
2006 Alexander GE, Chen K, Merkley TL, Reiman EM, Caselli RJ, Aschenbrenner M, Santerre-Lemmon L, Lewis DJ, Pietrini P, Teipel SJ, Hampel H, Rapoport SI, Moeller JR. Regional network of magnetic resonance imaging gray matter volume in healthy aging. Neuroreport. 17: 951-6. PMID 16791083 DOI: 10.1097/01.Wnr.0000220135.16844.B6  0.409
2006 Smith JF, Chen K, Johnson S, Morrone-Strupinsky J, Reiman EM, Nelson A, Moeller JR, Alexander GE. Network analysis of single-subject fMRI during a finger opposition task. Neuroimage. 32: 325-32. PMID 16733091 DOI: 10.1016/J.Neuroimage.2005.12.010  0.34
2006 Leow AD, Klunder AD, Jack CR, Toga AW, Dale AM, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Whitwell JL, Borowski BJ, Fleisher AS, Fox NC, Harvey D, Kornak J, ... ... Alexander GE, et al. Longitudinal stability of MRI for mapping brain change using tensor-based morphometry. Neuroimage. 31: 627-40. PMID 16480900 DOI: 10.1016/J.Neuroimage.2005.12.013  0.316
2006 Johnson SC, Schmitz TW, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, Hansen KW, Gleason CE, Carlsson CM, Ries ML, Asthana S, Chen K, Reiman EM, Alexander GE. Activation of brain regions vulnerable to Alzheimer's disease: the effect of mild cognitive impairment. Neurobiology of Aging. 27: 1604-12. PMID 16226349 DOI: 10.1016/J.Neurobiolaging.2005.09.017  0.486
2006 Bokde A, Alexander G, Moeller H, Rapoport S, Hampel H. IC-P-064: Discrimination between Alzheimer's disease patients and healthy subjects: Resting FDG-PET data Alzheimer's & Dementia. 2: S678-S679. DOI: 10.1016/J.Jalz.2006.05.2269  0.381
2006 Bokde A, Alexander G, Moeller H, Rapoport S, Hampel H. P2-259: Discrimination between Alzheimer's disease patients and healthy subjects: Resting FDG-PET data Alzheimer's & Dementia. 2: S313-S313. DOI: 10.1016/J.Jalz.2006.05.1098  0.388
2006 Caselli RJ, Hentz J, Osborne D, Snyder C, Alexander GE, Reiman EM. P2-194: Presymptomatic longitudinal decline in frontally mediated cognitive skills and memory in cognitively normal late middle aged APOE e4 carriers Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1032  0.399
2005 Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, Osborne D, Saunders AM, Hardy J. Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism. Proceedings of the National Academy of Sciences of the United States of America. 102: 8299-302. PMID 15932949 DOI: 10.1073/Pnas.0500579102  0.507
2005 Etnier JL, Caselli RJ, Alexander GE, Sibley BA, Tessier D, McLemore EC, Reiman EM. The Differential Benefits Of Aerobic Fitness For Cognitive Performance As A Function Of ApoE Genotype Medicine & Science in Sports & Exercise. 37: S462???S463. DOI: 10.1097/00005768-200505001-02416  0.331
2005 Reiman EM, Chen K, Caselli R, Bandy D, Lee W, Alexander G, Stephan D, Papassotiropoulos A. Correlations between cholesterol-related genetic risk scores and lower brain-imaging measurements of regional glucose metabolism Alzheimers & Dementia. 1. DOI: 10.1016/J.Jalz.2005.06.281  0.303
2005 Caselli RJ, Reiman EM, Chen K, Alexander GE, Osborne D, Parish J, Krahn L, Boeve BF. Resting FDG-PET in neurologically normal individuals reporting dream enactment behavior: Preclinical dementia with lewy bodies? Alzheimers & Dementia. 1. DOI: 10.1016/J.Jalz.2005.06.194  0.315
2004 Caselli RJ, Reiman EM, Hentz JG, Osborne D, Alexander GE. A distinctive interaction between chronic anxiety and problem solving in asymptomatic APOE e4 homozygotes. The Journal of Neuropsychiatry and Clinical Neurosciences. 16: 320-9. PMID 15377739 DOI: 10.1176/Appi.Neuropsych.16.3.320  0.306
2004 Ibáñez V, Pietrini P, Furey ML, Alexander GE, Millet P, Bokde AL, Teichberg D, Schapiro MB, Horwitz B, Rapoport SI. Resting state brain glucose metabolism is not reduced in normotensive healthy men during aging, after correction for brain atrophy. Brain Research Bulletin. 63: 147-54. PMID 15130704 DOI: 10.1016/J.Brainresbull.2004.02.003  0.395
2004 Chen K, Reiman EM, Alexander GE, Bandy D, Renaut R, Crum WR, Fox NC, Rossor MN. An automated algorithm for the computation of brain volume change from sequential MRIs using an iterative principal component analysis and its evaluation for the assessment of whole-brain atrophy rates in patients with probable Alzheimer's disease. Neuroimage. 22: 134-43. PMID 15110003 DOI: 10.1016/J.Neuroimage.2004.01.002  0.433
2004 Teipel SJ, Alexander GE, Schapiro MB, Möller HJ, Rapoport SI, Hampel H. Age-related cortical grey matter reductions in non-demented Down's syndrome adults determined by MRI with voxel-based morphometry. Brain : a Journal of Neurology. 127: 811-24. PMID 14985261 DOI: 10.1093/Brain/Awh101  0.475
2004 Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, Osborne D, Saunders AM, Hardy J. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proceedings of the National Academy of Sciences of the United States of America. 101: 284-9. PMID 14688411 DOI: 10.1073/Pnas.2635903100  0.501
2004 Teipel S, Alexander G, Schapiro M, Möller H, Rapoport S, Hampel H. Age-related cortical gray matter reductions in non-demented adults with Down’s syndrome determined by magnetic resonance imaging with optimized voxel-based morphometry Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825528  0.318
2004 Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, Prouty A. P3-071 Effects of apolipoprotein E ε4 gene dose and brain atrophy on baseline PET measurements of cerebral glucose metabolism Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81223-5  0.324
2004 Teipel SJ, Alexander GE, Schapiro MB, Möller H, Rapoport SI, Hampel H. P2-212 Age-related cortical grey matter reductions in nondemented down's syndrome adults determined by magnetic resonance imaging with voxel-based morphometry Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80958-8  0.347
2004 He T, Chen K, Reiman EM, Hicks C, Trouard T, Galons J, Hauss-Wegrzyniak B, Stevenson GD, Valla J, Wenk GL, Alexander GE. P2-192 The computation of mannitol-induced changes in mouse brain volume using sequential MRI and an iterative principal component analysis Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80938-2  0.301
2004 Chen K, Reiman EM, Caselli R, Bandy D, Alexander GE. P2-155 Linking functional and structural brain networks: study of normal aging using the partial least square and dimension reduction techniques Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80902-3  0.328
2004 Lin L, Chen K, Reiman EM, He T, Valla J, He J, Galons J, Hicks C, Trouard T, Hauss-Wegrzyniak B, Alexander G. P2-148 Template-based region of interest strategies for measuring ventricular volume in mouse brain MR images: empirical validation with pharmaceutical-induced ventricular increases Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80895-9  0.312
2003 Teipel SJ, Schapiro MB, Alexander GE, Krasuski JS, Horwitz B, Hoehne C, Möller HJ, Rapoport SI, Hampel H. Relation of corpus callosum and hippocampal size to age in nondemented adults with Down's syndrome. The American Journal of Psychiatry. 160: 1870-8. PMID 14514503 DOI: 10.1176/Appi.Ajp.160.10.1870  0.418
2003 Teipel SJ, Bayer W, Alexander GE, Bokde AL, Zebuhr Y, Teichberg D, Müller-Spahn F, Schapiro MB, Möller HJ, Rapoport SI, Hampel H. Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration. Neurobiology of Aging. 24: 85-94. PMID 12493554 DOI: 10.1016/S0197-4580(02)00044-1  0.46
2003 Lin L, Chen K, Alexander GE, He J, Valla J, Galons J, Hauss-Wegrzyniak B, Reiman EM. Construction of mouse brain MRI templates using SPM 99 Ifac Proceedings Volumes. 36: 113-118. DOI: 10.1016/S1474-6670(17)33484-5  0.318
2002 Hampel H, Teipel SJ, Alexander GE, Pogarell O, Rapoport SI, Möller HJ. In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EEG and PET. Journal of Neural Transmission (Vienna, Austria : 1996). 109: 837-55. PMID 12111472 DOI: 10.1007/S007020200069  0.477
2002 Caselli RJ, Reiman EM, Hentz JG, Osborne D, Alexander GE, Boeve BF. A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes. Sleep. 25: 447-53. PMID 12071547 DOI: 10.1093/Sleep/25.4.437  0.348
2002 Alexander GE, Chen K, Pietrini P, Rapoport SI, Reiman EM. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. The American Journal of Psychiatry. 159: 738-45. PMID 11986126 DOI: 10.1176/Appi.Ajp.159.5.738  0.458
2002 Teipel SJ, Bayer W, Alexander GE, Zebuhr Y, Teichberg D, Kulic L, Schapiro MB, Möller HJ, Rapoport SI, Hampel H. Progression of corpus callosum atrophy in Alzheimer disease. Archives of Neurology. 59: 243-8. PMID 11843695 DOI: 10.1001/Archneur.59.2.243  0.434
2002 Hampel H, Teipel SJ, Bayer W, Alexander GE, Schwarz R, Schapiro MB, Rapoport SI, Möller HJ. Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer's disease. Journal of the Neurological Sciences. 194: 15-9. PMID 11809161 DOI: 10.1016/S0022-510X(01)00669-4  0.427
2002 Krasuski JS, Alexander GE, Horwitz B, Rapoport SI, Schapiro MB. Relation of medial temporal lobe volumes to age and memory function in nondemented adults with Down's syndrome: implications for the prodromal phase of Alzheimer's disease. The American Journal of Psychiatry. 159: 74-81. PMID 11772693 DOI: 10.1176/Appi.Ajp.159.1.74  0.431
2001 Silverman DH, Small GW, Chang CY, Lu CS, Kung De Aburto MA, Chen W, Czernin J, Rapoport SI, Pietrini P, Alexander GE, Schapiro MB, Jagust WJ, Hoffman JM, Welsh-Bohmer KA, Alavi A, et al. Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. Jama. 286: 2120-7. PMID 11694153 DOI: 10.1001/Jama.286.17.2120  0.465
2001 Caselli RJ, Osborne D, Reiman EM, Hentz JG, Barbieri CJ, Saunders AM, Hardy J, Graff-Radford NR, Hall GR, Alexander GE. Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study. Journal of the Neurological Sciences. 189: 93-8. PMID 11535238 DOI: 10.1016/S0022-510X(01)00577-9  0.343
2001 Huang W, Alexander GE, Chang L, Shetty HU, Krasuski JS, Rapoport SI, Schapiro MB. Brain metabolite concentration and dementia severity in Alzheimer's disease: a (1)H MRS study. Neurology. 57: 626-32. PMID 11524470 DOI: 10.1212/Wnl.57.4.626  0.427
2001 Bokde AL, Pietrini P, Ibáñez V, Furey ML, Alexander GE, Graff-Radford NR, Rapoport SI, Schapiro MB, Horwitz B. The effect of brain atrophy on cerebral hypometabolism in the visual variant of Alzheimer disease. Archives of Neurology. 58: 480-6. PMID 11255453 DOI: 10.1001/Archneur.58.3.480  0.446
2001 Reiman EM, Caselli RJ, Chen K, Alexander GE, Bandy D, Frost J. Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 3334-9. PMID 11248079 DOI: 10.1073/Pnas.061509598  0.493
2001 Reiman EM, Caselli RJ, Alexander GE, Chen K. Tracking the decline in cerebral glucose metabolism in persons and laboratory animals at genetic risk for Alzheimer's disease Clinical Neuroscience Research. 1: 194-206. DOI: 10.1016/S1566-2772(01)00006-8  0.488
2000 Levine BK, Beason-Held LL, Purpura KP, Aronchick DM, Optican LM, Alexander GE, Horwitz B, Rapoport SI, Schapiro MB. Age-related differences in visual perception: a PET study. Neurobiology of Aging. 21: 577-84. PMID 10924775 DOI: 10.1016/S0197-4580(00)00144-5  0.365
2000 Furey ML, Pietrini P, Alexander GE, Mentis MJ, Szczepanik J, Shetty U, Greig NH, Holloway HW, Schapiro MB, Freo U. Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans. Pharmacology, Biochemistry, and Behavior. 66: 475-81. PMID 10899358 DOI: 10.1016/S0091-3057(00)00186-6  0.319
2000 Pietrini P, Alexander GE, Furey ML, Hampel H, Guazzelli M. The neurometabolic landscape of cognitive decline: in vivo studies with positron emission tomography in Alzheimer's disease. International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology. 37: 87-98. PMID 10828377 DOI: 10.1016/S0167-8760(00)00097-0  0.482
2000 Hampel H, Teipel SJ, Alexander GE, Horwitz B, Pietrini P, Hippius H, Möller HJ, Schapiro MB, Rapoport SI. Corpus callosum measurement as an in vivo indicator for neocortical neuronal integrity, but not white matter pathology, in Alzheimer's disease. Annals of the New York Academy of Sciences. 903: 470-6. PMID 10818540 DOI: 10.1111/J.1749-6632.2000.Tb06401.X  0.364
2000 Pietrini P, Alexander GE, Furey ML, Dani A, Mentis MJ, Horwitz B, Guazzelli M, Shapiro MB, Rapoport SI. Cerebral metabolic response to passive audiovisual stimulation in patients with Alzheimer's disease and healthy volunteers assessed by PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 41: 575-83. PMID 10768555  0.373
2000 Furey ML, Pietrini P, Alexander GE, Schapiro MB, Horwitz B. Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans. Brain Research Bulletin. 51: 213-8. PMID 10718513 DOI: 10.1016/S0361-9230(99)00219-1  0.349
2000 Carlin D, Bonerba J, Phipps M, Alexander G, Shapiro M, Grafman J. Planning impairments in frontal lobe dementia and frontal lobe lesion patients. Neuropsychologia. 38: 655-65. PMID 10689042 DOI: 10.1016/S0028-3932(99)00102-5  0.365
2000 Hampel H, Teipel S, Bayer W, Alexander G, Schapiro M, Möller H, Rapoport S. Progression of corpus callosum and hippocampus atrophy as independent markers of structural disease progression in Alzheimer's disease European Neuropsychopharmacology. 10: 371-372. DOI: 10.1016/S0924-977X(00)80501-5  0.381
2000 Teipel S, Bayer W, Alexander G, Möller H, Hampel H, Schapiro M, Rapoport S. Increased diagnostic accuracy in Alzheimer's disease by age-transformed hippocampal volumes European Neuropsychopharmacology. 10: 371. DOI: 10.1016/S0924-977X(00)80499-X  0.397
2000 Pietrini P, Strassburger TL, Alexander GE, Brady DR, Mentis MJ, Rapoport SI, Schapiro MB, Grady CL. Heterogeneity of regional cerebral glucose metabolic patterns in neuropathologically confirmed Alzheimer's disease patients Neurobiology of Aging. 21: 251. DOI: 10.1016/S0197-4580(00)83466-1  0.398
2000 Alexander GE, Chen K, Pietrini P, Rapoport SI, Reiman EM. Evaluation of cerebral decline in Alzheimer's dementia: Implications for using resting positron emission tomography and magnetic resonance imaging morphometry as outcome measures in long-term treatment studies Neurobiology of Aging. 21: 40. DOI: 10.1016/S0197-4580(00)82853-5  0.361
2000 Reiman EM, Caselli RJ, Chen K, Alexander GE, Bandy D, Gonzalez-Lima F. Functional brain imaging in subjects at genetic risk for Alzheimer's disease Neurobiology of Aging. 21: 141. DOI: 10.1016/S0197-4580(00)82433-1  0.382
2000 Teipel SJ, Rapoport SI, Bayer W, Alexander GE, Moeller H. Age-transformation of hippocampal volumes improves diagnostic accuracy in Alzheimer's disease Neurobiology of Aging. 21: 106. DOI: 10.1016/S0197-4580(00)82277-0  0.395
2000 Hampel H, Teipel SJ, Bayer W, Alexander GE, Schapiro MB, Moeller H, Rapoport SI. Progression of hippocampus and corpus callosum atrophy as independent markers of structural disease progression in Alzheimer's disease Neurobiology of Aging. 21: 177. DOI: 10.1016/S0197-4580(00)82136-3  0.381
1999 Dimitrov M, Granetz J, Peterson M, Hollnagel C, Alexander G, Grafman J. Associative learning impairments in patients with frontal lobe damage. Brain and Cognition. 41: 213-30. PMID 10590820 DOI: 10.1006/Brcg.1999.1121  0.32
1999 Huang W, Alexander GE, Daly EM, Shetty HU, Krasuski JS, Rapoport SI, Schapiro MB. High brain myo-inositol levels in the predementia phase of Alzheimer's disease in adults with Down's syndrome: a 1H MRS study. The American Journal of Psychiatry. 156: 1879-86. PMID 10588400 DOI: 10.1176/Ajp.156.12.1879  0.409
1999 Keilp JG, Gorlyn M, Alexander GE, Stern Y, Prohovnik I. Cerebral blood flow patterns underlying the differential impairment in category vs letter fluency in Alzheimer's disease. Neuropsychologia. 37: 1251-61. PMID 10530725 DOI: 10.1016/S0028-3932(99)00032-9  0.419
1999 Alexander GE, Mentis MJ, Van Horn JD, Grady CL, Berman KF, Furey ML, Pietrini P, Rapoport SI, Schapiro MB, Moeller JR. Individual differences in PET activation of object perception and attention systems predict face matching accuracy. Neuroreport. 10: 1965-71. PMID 10501542 DOI: 10.1097/00001756-199906230-00032  0.35
1999 Schapiro MB, Berman KF, Alexander GE, Weinberger DR, Rapoport SI. Regional cerebral blood flow in Down syndrome adults during the Wisconsin Card Sorting Test: exploring cognitive activation in the context of poor performance. Biological Psychiatry. 45: 1190-6. PMID 10331111 DOI: 10.1016/S0006-3223(98)00051-1  0.35
1999 Teipel SJ, Hampel H, Pietrini P, Alexander GE, Horwitz B, Daley E, Möller HJ, Schapiro MB, Rapoport SI. Region-specific corpus callosum atrophy correlates with the regional pattern of cortical glucose metabolism in Alzheimer disease. Archives of Neurology. 56: 467-73. PMID 10199337 DOI: 10.1001/Archneur.56.4.467  0.44
1999 Pietrini P, Furey ML, Alexander GE, Mentis MJ, Dani A, Guazzelli M, Rapoport SI, Schapiro MB. Association between brain functional failure and dementia severity in Alzheimer's disease: resting versus stimulation PET study. The American Journal of Psychiatry. 156: 470-3. PMID 10080567 DOI: 10.1176/Ajp.156.3.470  0.393
1999 Hooker CM, Szczepanik J, Furey ML, Pietrini P, Mentis MJ, Levine B, Schapiro MB, Rapoport SI, Alexander GE. Effect of heterogeneity in patterns of cognitive function and dementia severity on cognitive decline in Alzheimer's disease Archives of Clinical Neuropsychology. 14: 52-53. DOI: 10.1093/Arclin/14.1.52  0.433
1998 Teipel SJ, Hampel H, Alexander GE, Schapiro MB, Horwitz B, Teichberg D, Daley E, Hippius H, Möller HJ, Rapoport SI. Dissociation between corpus callosum atrophy and white matter pathology in Alzheimer's disease. Neurology. 51: 1381-5. PMID 9818864 DOI: 10.1212/Wnl.51.5.1381  0.429
1998 Beason-Held LL, Purpura KP, Van Meter JW, Azari NP, Mangot DJ, Optican LM, Mentis MJ, Alexander GE, Grady CL, Horwitz B, Rapoport SI, Schapiro MB. PET reveals occipitotemporal pathway activation during elementary form perception in humans. Visual Neuroscience. 15: 503-10. PMID 9685203 DOI: 10.1017/S0952523898153117  0.335
1998 Ibáñez V, Pietrini P, Alexander GE, Furey ML, Teichberg D, Rajapakse JC, Rapoport SI, Schapiro MB, Horwitz B. Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease. Neurology. 50: 1585-93. PMID 9633698 DOI: 10.1212/Wnl.50.6.1585  0.402
1998 Mentis MJ, Alexander GE, Krasuski J, Pietrini P, Furey ML, Schapiro MB, Rapoport SI. Increasing required neural response to expose abnormal brain function in mild versus moderate or severe Alzheimer's disease: PET study using parametric visual stimulation. The American Journal of Psychiatry. 155: 785-94. PMID 9619151 DOI: 10.1176/Ajp.155.6.785  0.441
1998 Hampel H, Teipel SJ, Alexander GE, Horwitz B, Teichberg D, Schapiro MB, Rapoport SI. Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Archives of Neurology. 55: 193-8. PMID 9482361 DOI: 10.1001/Archneur.55.2.193  0.445
1998 Krasuski JS, Alexander GE, Horwitz B, Daly EM, Murphy DG, Rapoport SI, Schapiro MB. Volumes of medial temporal lobe structures in patients with Alzheimer's disease and mild cognitive impairment (and in healthy controls). Biological Psychiatry. 43: 60-8. PMID 9442345 DOI: 10.1016/S0006-3223(97)00013-9  0.479
1998 Bokde ALW, Ibáñez V, Pietrini P, Furey ML, Alexander GE, Graff-Radford NR, Rapoport SI, Schapiro MB, Horwitz B. Cerebral glucose hypometabolism in the visual variant of Alzheimer's disease after correcting for brain atrophy Neuroimage. 7: S628. DOI: 10.1016/S1053-8119(18)31461-7  0.399
1997 Mentis MJ, Alexander GE, Grady CL, Horwitz B, Krasuski J, Pietrini P, Strassburger T, Hampel H, Schapiro MB, Rapoport SI. Frequency variation of a pattern-flash visual stimulus during PET differentially activates brain from striate through frontal cortex. Neuroimage. 5: 116-28. PMID 9345542 DOI: 10.1006/Nimg.1997.0256  0.358
1997 Pietrini P, Dani A, Furey ML, Alexander GE, Freo U, Grady CL, Mentis MJ, Mangot D, Simon EW, Horwitz B, Haxby JV, Schapiro MB. Low glucose metabolism during brain stimulation in older Down's syndrome subjects at risk for Alzheimer's disease prior to dementia. The American Journal of Psychiatry. 154: 1063-9. PMID 9247390 DOI: 10.1176/Ajp.154.8.1063  0.45
1997 Strassburger TL, Lee HC, Daly EM, Szczepanik J, Krasuski JS, Mentis MJ, Salerno JA, DeCarli C, Schapiro MB, Alexander GE. Interactive effects of age and hypertension on volumes of brain structures. Stroke; a Journal of Cerebral Circulation. 28: 1410-7. PMID 9227693 DOI: 10.1161/01.Str.28.7.1410  0.365
1997 Alexander GE, Saunders AM, Szczepanik J, Strassburger TL, Pietrini P, Dani A, Furey ML, Mentis MJ, Roses AD, Rapoport SI, Schapiro MB. Relation of age and apolipoprotein E to cognitive function in Down syndrome adults. Neuroreport. 8: 1835-40. PMID 9223061 DOI: 10.1097/00001756-199705260-00009  0.449
1997 Furey ML, Pietrini P, Haxby JV, Alexander GE, Lee HC, VanMeter J, Grady CL, Shetty U, Rapoport SI, Schapiro MB, Freo U. Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory. Proceedings of the National Academy of Sciences of the United States of America. 94: 6512-6. PMID 9177249 DOI: 10.1073/Pnas.94.12.6512  0.33
1997 Greenwood PM, Parasuraman R, Alexander GE. Controlling the focus of spatial attention during visual search: effects of advanced aging and Alzheimer disease. Neuropsychology. 11: 3-12. PMID 9055265 DOI: 10.1037/0894-4105.11.1.3  0.345
1997 Alexander GE, Furey ML, Grady CL, Pietrini P, Brady DR, Mentis MJ, Schapiro MB. Association of premorbid intellectual function with cerebral metabolism in Alzheimer's disease: implications for the cognitive reserve hypothesis. The American Journal of Psychiatry. 154: 165-72. PMID 9016263 DOI: 10.1176/Ajp.154.2.165  0.483
1997 Pietrini P, Dani A, Furey M, Alexander G, Freo U, Mentis M, Schapiro M. Cerebral glucose metabolism before and after onset of dementia in down syndrome: A position emission tomography (PET) study Biological Psychiatry. 42: 211S. DOI: 10.1016/S0006-3223(97)87780-3  0.319
1996 Dani A, Pietrini P, Furey ML, McIntosh AR, Grady CL, Horwitz B, Freo U, Alexander GE, Schapiro MB. Brain cognition and metabolism in Down syndrome adults in association with development of dementia. Neuroreport. 7: 2933-6. PMID 9116213 DOI: 10.1097/00001756-199611250-00026  0.474
1996 Keilp JG, Alexander GE, Stern Y, Prohovnik I. Inferior parietal perfusion, lateralization, and neuropsychological dysfunction in Alzheimer's disease. Brain and Cognition. 32: 365-83. PMID 8975677 DOI: 10.1006/Brcg.1996.0071  0.434
1996 Pietrini P, Furey ML, Graff-Radford N, Freo U, Alexander GE, Grady CL, Dani A, Mentis MJ, Schapiro MB. Preferential metabolic involvement of visual cortical areas in a subtype of Alzheimer's disease: clinical implications. The American Journal of Psychiatry. 153: 1261-8. PMID 8831432 DOI: 10.1176/Ajp.153.10.1261  0.438
1996 Moeller JR, Ishikawa T, Dhawan V, Spetsieris P, Mandel F, Alexander GE, Grady C, Pietrini P, Eidelberg D. The metabolic topography of normal aging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 385-98. PMID 8621743 DOI: 10.1097/00004647-199605000-00005  0.374
1996 Mentis MJ, Horwitz B, Grady CL, Alexander GE, VanMeter JW, Maisog JM, Pietrini P, Schapiro MB, Rapoport SI. Visual cortical dysfunction in Alzheimer's disease evaluated with a temporally graded "stress test" during PET. The American Journal of Psychiatry. 153: 32-40. PMID 8540589 DOI: 10.1176/Ajp.153.1.32  0.415
1996 Furey-Kurkjian ML, Pietrini P, Graff-Radford NR, Alexander GE, Freo U, Szczepanik J, Schapiro MB. Visual variant of Alzheimer disease: Distinctive neuropsychological features Neuropsychology. 10: 294-300. DOI: 10.1037/0894-4105.10.2.294  0.345
1996 Mentis M, Horwitz B, Grady C, Alexander G, Furey M, Schapiro M, Rapoport S. Visual processing is abnormal in striate and association areas in Alzheimer's disease Biological Psychiatry. 39: 662. DOI: 10.1016/0006-3223(96)84487-8  0.364
1996 Pietrini P, Dani A, Furey M, Freo U, Horwitz B, Mentis M, Alexander G, Grady C, Schapiro M, Rapoport S. Brain stimulation reverses cerebral metabolic reductions in Alzheimer disease Biological Psychiatry. 39: 660. DOI: 10.1016/0006-3223(96)84482-9  0.38
1995 Schapiro MB, Murphy DG, Hagerman RJ, Azari NP, Alexander GE, Miezejeski CM, Hinton VJ, Horwitz B, Haxby JV, Kumar A. Adult fragile X syndrome: neuropsychology, brain anatomy, and metabolism. American Journal of Medical Genetics. 60: 480-93. PMID 8825884 DOI: 10.1002/Ajmg.1320600603  0.367
1995 Mentis MJ, Weinstein EA, Horwitz B, McIntosh AR, Pietrini P, Alexander GE, Furey M, Murphy DG. Abnormal brain glucose metabolism in the delusional misidentification syndromes: a positron emission tomography study in Alzheimer disease. Biological Psychiatry. 38: 438-49. PMID 8672604 DOI: 10.1016/0006-3223(94)00326-X  0.465
1995 Parasuraman R, Greenwood PM, Alexander GE. Selective impairment of spatial attention during visual search in Alzheimer's disease. Neuroreport. 6: 1861-4. PMID 8547585 DOI: 10.1097/00001756-199510020-00010  0.374
1995 Stern Y, Alexander GE, Prohovnik I, Stricks L, Link B, Lennon MC, Mayeux R. Relationship between lifetime occupation and parietal flow: implications for a reserve against Alzheimer's disease pathology. Neurology. 45: 55-60. PMID 7824135 DOI: 10.1212/Wnl.45.1.55  0.393
1994 Alexander GE, Prohovnik I, Stern Y, Mayeux R. WAIS-R subtest profile and cortical perfusion in Alzheimer's disease. Brain and Cognition. 24: 24-43. PMID 8123262 DOI: 10.1006/Brcg.1994.1002  0.399
1994 Alexander GE, Moeller JR. Application of the scaled subprofile model to functional imaging in neuropsychiatric disorders: A principal component approach to modeling brain function in disease Human Brain Mapping. 2: 79-94. DOI: 10.1002/Hbm.460020108  0.391
1992 Stern Y, Alexander GE, Prohovnik I, Mayeux R. Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease. Annals of Neurology. 32: 371-5. PMID 1416806 DOI: 10.1002/Ana.410320311  0.378
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