Richard P. Kraig - Publications

Neurobiology University of Chicago, Chicago, IL 
Neuroscience Biology

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pusic KM, Kraig RP, Pusic AD. IFNγ-stimulated dendritic cell extracellular vesicles can be nasally administered to the brain and enter oligodendrocytes. Plos One. 16: e0255778. PMID 34388189 DOI: 10.1371/journal.pone.0255778  1
2021 Won L, Kraig RP. Insulin-Like Growth Factor-1 Inhibits Nitroglycerin-Induced Trigeminal Activation of Oxidative Stress, Calcitonin Gene-Related Peptide and c-Fos Expression. Neuroscience Letters. 135809. PMID 33713748 DOI: 10.1016/j.neulet.2021.135809  1
2020 Won L, Kraig RP. Insulin-Like Growth Factor-1 Inhibits Spreading Depression-Induced Trigeminal Calcitonin Gene Related Peptide, Oxidative Stress & Neuronal Activation in Rat. Brain Research. 146673. PMID 31978377 DOI: 10.1016/J.Brainres.2020.146673  1
2019 Pusic KM, Won L, Kraig RP, Pusic AD. IFNγ-Stimulated Dendritic Cell Exosomes for Treatment of Migraine Modeled Using Spreading Depression. Frontiers in Neuroscience. 13: 942. PMID 31551696 DOI: 10.3389/Fnins.2019.00942  1
2017 Grinberg YY, Zitzow LA, Kraig RP. Intranasally Administered IGF-1 Inhibits Spreading Depression In Vivo. Brain Research. PMID 28951235 DOI: 10.1016/J.Brainres.2017.09.022  1
2017 Ochocinska MJ, Zlokovic BV, Searson PC, Crowder AT, Kraig RP, Ljubimova JY, Mainprize TG, Banks WA, Warren RQ, Kindzelski A, Timmer W, Liu CH. NIH workshop report on the trans-agency blood-brain interface workshop 2016: exploring key challenges and opportunities associated with the blood, brain and their interface. Fluids and Barriers of the Cns. 14: 12. PMID 28457227 DOI: 10.1186/S12987-017-0061-6  0.01
2016 Pusic KM, Pusic AD, Kraig RP. Environmental Enrichment Stimulates Immune Cell Secretion of Exosomes that Promote CNS Myelination and May Regulate Inflammation. Cellular and Molecular Neurobiology. PMID 26993508 DOI: 10.1007/S10571-015-0269-4  1
2015 Quesenberry PJ, Aliotta J, Camussi G, Abdel-Mageed AB, Wen S, Goldberg L, Zhang HG, Tetta C, Franklin J, Coffey RJ, Danielson K, Subramanya V, Ghiran I, Das S, Chen CC, ... ... Kraig RP, et al. Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium. Journal of Extracellular Vesicles. 4: 27575. PMID 26320942 DOI: 10.3402/Jev.V4.27575  1
2015 Pusic AD, Kraig RP. Phasic Treatment with Interferon Gamma Stimulates Release of Exosomes that Protect Against Spreading Depression. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 35: 795-807. PMID 26083947 DOI: 10.1089/Jir.2015.0010  1
2015 Pusic AD, Mitchell HM, Kunkler PE, Klauer N, Kraig RP. Spreading depression transiently disrupts myelin via interferon-gamma signaling. Experimental Neurology. 264: 43-54. PMID 25500111 DOI: 10.1016/J.Expneurol.2014.12.001  1
2014 Pusic KM, Pusic AD, Kemme J, Kraig RP. Spreading depression requires microglia and is decreased by their M2a polarization from environmental enrichment. Glia. 62: 1176-94. PMID 24723305 DOI: 10.1002/Glia.22672  1
2014 Pusic AD, Pusic KM, Kraig RP. What are exosomes and how can they be used in multiple sclerosis therapy? Expert Review of Neurotherapeutics. 14: 353-5. PMID 24552578 DOI: 10.1586/14737175.2014.890893  1
2014 Pusic AD, Kraig RP. Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination. Glia. 62: 284-99. PMID 24339157 DOI: 10.1002/Glia.22606  1
2014 Pusic AD, Pusic KM, Clayton BL, Kraig RP. IFNγ-stimulated dendritic cell exosomes as a potential therapeutic for remyelination. Journal of Neuroimmunology. 266: 12-23. PMID 24275061 DOI: 10.1016/J.Jneuroim.2013.10.014  1
2013 Grinberg YY, Dibbern ME, Levasseur VA, Kraig RP. Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-α responses to spreading depression. Journal of Neurochemistry. 126: 662-72. PMID 23586526 DOI: 10.1111/Jnc.12267  1
2012 Walters R, Kraig RP, Medintz I, Delehanty JB, Stewart MH, Susumu K, Huston AL, Dawson PE, Dawson G. Nanoparticle targeting to neurons in a rat hippocampal slice culture model. Asn Neuro. 4: 383-92. PMID 22973864 DOI: 10.1042/An20120042  1
2012 Grinberg YY, van Drongelen W, Kraig RP. Insulin-like growth factor-1 lowers spreading depression susceptibility and reduces oxidative stress. Journal of Neurochemistry. 122: 221-9. PMID 22524542 DOI: 10.1111/J.1471-4159.2012.07763.X  1
2012 Cipolla MJ, Pusic AD, Grinberg YY, Chapman AC, Poynter ME, Kraig RP. Pregnant serum induces neuroinflammation and seizure activity via TNFα. Experimental Neurology. 234: 398-404. PMID 22281105 DOI: 10.1016/J.Expneurol.2012.01.005  1
2011 Cipolla MJ, Kraig RP. Seizures in Women with Preeclampsia: Mechanisms and Management. Fetal and Maternal Medicine Review. 22: 91-108. PMID 21709815 DOI: 10.1017/S0965539511000040  1
2011 Pusic AD, Grinberg YY, Mitchell HM, Kraig RP. Modeling neural immune signaling of episodic and chronic migraine using spreading depression in vitro. Journal of Visualized Experiments : Jove. PMID 21694695 DOI: 10.3791/2910  1
2011 Cipolla MJ, Houston EM, Kraig RP, Bonney EA. Differential effects of low-dose endotoxin on the cerebral circulation during pregnancy. Reproductive Sciences (Thousand Oaks, Calif.). 18: 1211-21. PMID 21693776 DOI: 10.1177/1933719111410712  1
2011 Grinberg YY, Milton JG, Kraig RP. Spreading depression sends microglia on Lévy flights. Plos One. 6: e19294. PMID 21541289 DOI: 10.1371/Journal.Pone.0019294  1
2011 Domowicz MS, Henry JG, Wadlington N, Navarro A, Kraig RP, Schwartz NB. Astrocyte precursor response to embryonic brain injury. Brain Research. 1389: 35-49. PMID 21396923 DOI: 10.1016/J.Brainres.2011.03.006  1
2011 Mitchell HM, White DM, Domowicz MS, Kraig RP. Cold pre-conditioning neuroprotection depends on TNF-α and is enhanced by blockade of interleukin-11. Journal of Neurochemistry. 117: 187-96. PMID 21070241 DOI: 10.1111/J.1471-4159.2010.07103.X  1
2010 Kraig RP, Mitchell HM, Christie-Pope B, Kunkler PE, White DM, Tang YP, Langan G. TNF-α and Microglial Hormetic Involvement in Neurological Health & Migraine. Dose-Response : a Publication of International Hormesis Society. 8: 389-413. PMID 21191481 DOI: 10.2203/Dose-Response.09-056.Kraig  1
2010 Mitchell HM, White DM, Kraig RP. Strategies for study of neuroprotection from cold-preconditioning. Journal of Visualized Experiments : Jove. PMID 20834222 DOI: 10.3791/2192  1
2008 Hulse RE, Swenson WG, Kunkler PE, White DM, Kraig RP. Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12199-211. PMID 19020014 DOI: 10.1523/Jneurosci.3856-08.2008  1
2008 Lin W, Kunkler PE, Harding HP, Ron D, Kraig RP, Popko B. Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma. The American Journal of Pathology. 173: 1508-17. PMID 18818381 DOI: 10.2353/Ajpath.2008.080449  1
2005 Kunkler PE, Hulse RE, Schmitt MW, Nicholson C, Kraig RP. Optical current source density analysis in hippocampal organotypic culture shows that spreading depression occurs with uniquely reversing currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3952-61. PMID 15829647 DOI: 10.1523/Jneurosci.0491-05.2005  1
2004 Kunkler PE, Hulse RE, Kraig RP. Multiplexed cytokine protein expression profiles from spreading depression in hippocampal organotypic cultures. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 829-39. PMID 15362713 DOI: 10.1097/01.Wcb.0000126566.34753.30  1
2004 Kunkler PE, Kraig RP. P/Q Ca2+ channel blockade stops spreading depression and related pyramidal neuronal Ca2+ rise in hippocampal organ culture. Hippocampus. 14: 356-67. PMID 15132435 DOI: 10.1002/Hipo.10181  1
2004 Hulse RE, Kunkler PE, Fedynyshyn JP, Kraig RP. Optimization of multiplexed bead-based cytokine immunoassays for rat serum and brain tissue. Journal of Neuroscience Methods. 136: 87-98. PMID 15126049 DOI: 10.1016/J.Jneumeth.2003.12.023  1
2004 Aptowicz CO, Kunkler PE, Kraig RP. Homeostatic plasticity in hippocampal slice cultures involves changes in voltage-gated Na+ channel expression. Brain Research. 998: 155-63. PMID 14751586 DOI: 10.1016/J.Brainres.2003.11.035  1
2003 Kunkler PE, Kraig RP. Hippocampal spreading depression bilaterally activates the caudal trigeminal nucleus in rodents. Hippocampus. 13: 835-44. PMID 14620879 DOI: 10.1002/Hipo.10139  1
2001 Hulse RE, Winterfield J, Kunkler PE, Kraig RP. Astrocytic clasmatodendrosis in hippocampal organ culture. Glia. 33: 169-79. PMID 11180514 DOI: 10.1002/1098-1136(200102)33:2<169::Aid-Glia1016>3.0.Co;2-B  1
1999 Caggiano AO, Kraig RP. Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1β production Journal of Neurochemistry. 72: 565-575. PMID 9930728 DOI: 10.1046/J.1471-4159.1999.0720565.X  1
1998 Caggiano AO, Kraig RP. Prostaglandin E2 and 4-aminopyridine prevent the lipopolysaccharide- induced outwardly rectifying potassium current and interleukin-1β production in cultured rat microglia Journal of Neurochemistry. 70: 2357-2368. PMID 9603200 DOI: 10.1046/J.1471-4159.1998.70062357.X  1
1998 Kunkler PE, Kraig RP. Calcium waves precede electrophysiological changes of spreading depression in hippocampal organ cultures Journal of Neuroscience. 18: 3416-3425. PMID 9547248 DOI: 10.1523/Jneurosci.18-09-03416.1998  1
1998 Lascola CD, Nelson DJ, Kraig RP. Cytoskeletal actin gates a Cl- channel in neocortical astrocytes Journal of Neuroscience. 18: 1679-1692. PMID 9464993 DOI: 10.1523/Jneurosci.18-05-01679.1998  1
1998 Caggiano AO, Kraig RP. Neuronal nitric oxide synthase expression is induced in neocortical astrocytes after spreading depression Journal of Cerebral Blood Flow and Metabolism. 18: 75-87. PMID 9428308 DOI: 10.1097/00004647-199801000-00008  1
1997 Lascola C, Kraig RP. Astroglial acid-base dynamics in hyperglycemic and normoglycemic global ischemia Neuroscience and Biobehavioral Reviews. 21: 143-150. PMID 9062937 DOI: 10.1016/S0149-7634(96)00004-8  1
1997 Kunkler PE, Kraig RP. Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo Journal of Cerebral Blood Flow and Metabolism. 17: 26-43. PMID 8978384 DOI: 10.1097/00004647-199701000-00005  1
1997 Lascola CD, Kraig RP. Astrocyte Reaction to Global Ischemic Brain Injury Primer On Cerebrovascular Diseases. 114-117. DOI: 10.1016/B978-012743170-3.50033-9  1
1996 Caggiano AO, Breder CD, Kraig RP. Long-term elevation of cyclooxygenase-2, but not lipoxygenase, in regions synaptically distant from spreading depression. The Journal of Comparative Neurology. 376: 447-62. PMID 8956110 DOI: 10.1002/(Sici)1096-9861(19961216)376:3<447::Aid-Cne7>3.0.Co;2-2  1
1996 Lascola CD, Kraig RP. Whole-cell chloride currents in rat astrocytes accompany changes in cell morphology Journal of Neuroscience. 16: 2532-2545. PMID 8786429 DOI: 10.1523/Jneurosci.16-08-02532.1996  1
1996 Caggiano AO, Kraig RP. Eicosanoids and nitric oxide influence induction of reactive gliosis from spreading depression in microglia but not astrocytes Journal of Comparative Neurology. 369: 93-108. PMID 8723705 DOI: 10.1002/(Sici)1096-9861(19960520)369:1<93::Aid-Cne7>3.0.Co;2-F  1
1995 Breder CD, Dewitt D, Kraig RP. Characterization of inducible cyclooxygenase in rat brain. The Journal of Comparative Neurology. 355: 296-315. PMID 7608344 DOI: 10.1002/Cne.903550208  1
1995 Lascola CD, Kraig RP. [10] Brain cell acid-base changes measured with ion-selective microelectrodes Methods in Neurosciences. 27: 214-232. DOI: 10.1016/S1043-9471(06)80013-3  1
1994 Chesler M, Chen JCT, Kraig RP. Determination of extracellular bicarbonate and carbon dioxide concentrations in brain slices using carbonate and pH-selective microelectrodes Journal of Neuroscience Methods. 53: 129-136. PMID 7823615 DOI: 10.1016/0165-0270(94)90169-4  1
1993 Moskowitz MA, Nozaki K, Kraig RP. Neocortical spreading depression provokes the expression of c-fos protein- like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms Journal of Neuroscience. 13: 1167-1177. PMID 8382735 DOI: 10.1523/Jneurosci.13-03-01167.1993  1
1991 Nedergaard M, Kraig RP, Tanabe J, Pulsinelli WA. Dynamics of interstitial and intracellular pH in evolving brain infarct. The American Journal of Physiology. 260: R581-8. PMID 2001008 DOI: 10.1152/Ajpregu.1991.260.3.R581  1
1991 Kraig RP, Dong L, Thisted R, Jaeger CB. Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein Journal of Neuroscience. 11: 2187-2198. PMID 1906091 DOI: 10.1523/Jneurosci.11-07-02187.1991  1
1991 Iadecola C, Kraig RP. Focal elevations in neocortical interstitial K+ produced by stimulation of the fastigial nucleus in rat Brain Research. 563: 273-277. PMID 1786540 DOI: 10.1016/0006-8993(91)91544-B  1
1991 Swain MS, Blei AT, Butterworth RF, Kraig RP. Intracellular pH rises and astrocytes swell after portacaval anastomosis in rats. The American Journal of Physiology. 261: R1491-6. PMID 1750572 DOI: 10.1152/Ajpregu.1991.261.6.R1491  1
1991 Wietasch K, Kraig RP. Carbonic acid buffer species measured in real time with an intracellular microelectrode array American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 261. PMID 1653544 DOI: 10.1152/Ajpregu.1991.261.3.R760  1
1990 Kraig RP, Chesler M. Astrocytic acidosis in hyperglycemic and complete ischemia Journal of Cerebral Blood Flow and Metabolism. 10: 104-114. PMID 2298827 DOI: 10.1038/Jcbfm.1990.13  1
1990 Kraig RP, Jaeger CB. Ionic concomitants of astroglial transformation to reactive species Stroke. 21. PMID 2237980  1
1989 Kraig RP. Astroglial H+ and Ca2+ changes--signals for cell activation? Acta Physiologica Scandinavica, Supplement. 582: 32. PMID 2816434  1
1989 Goldman SA, Pulsinelli WA, Clarke WY, Kraig RP, Plum F. The effects of extracellular acidosis on neurons and glia in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 9: 471-7. PMID 2738113 DOI: 10.1038/Jcbfm.1989.70  1
1989 Chesler M, Kraig RP. Intracellular pH transients of mammalian astrocytes Journal of Neuroscience. 9: 2011-2019. PMID 2723764 DOI: 10.1523/Jneurosci.09-06-02011.1989  1
1988 Kraig RP. Acid-induced injury in elasmobranch brain Neuroscience Letters. 90: 119-124. PMID 3412631 DOI: 10.1016/0304-3940(88)90797-5  1
1988 Plum F, Kraig RP, Pulsinelli WA. Compartmentation of acid-base balance in brain during complete ischemia. Neurochemical Pathology. 9: 139-44. PMID 3247068 DOI: 10.1007/Bf03160359  1
1987 Kraig RP, Cooper AJL. Bicarbonate and ammonia changes in brain during spreading depression Canadian Journal of Physiology and Pharmacology. 65: 1099-1104. PMID 3621035 DOI: 10.1139/Y87-172  1
1987 Kraig RP, Petito CK, Plum F, Pulsinelli WA. Hydrogen ions kill brain at concentrations reached in ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 7: 379-86. PMID 3611202 DOI: 10.1038/Jcbfm.1987.80  1
1987 Kraig RP, Wagner RJ. Acid-induced changes of brain protein buffering Brain Research. 410: 390-394. PMID 3594248 DOI: 10.1016/0006-8993(87)90345-3  1
1987 Chesler M, Kraig RP. Intracellular pH of astrocytes increases rapidly with cortical stimulation American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 253. PMID 3116863 DOI: 10.1152/Ajpregu.1987.253.4.R666  1
1987 Petito CK, Kraig RP, Pulsinelli WA. Light and electron microscopic evaluation of hydrogen ion-induced brain necrosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 7: 625-32. PMID 2821031 DOI: 10.1038/Jcbfm.1987.115  1
1986 Arnold JB, Kraig RP, Rottenberg DA. In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 6: 435-40. PMID 3733903 DOI: 10.1038/Jcbfm.1986.76  1
1986 Kraig RP, Pulsinelli WA, Plum F. Carbonic acid buffer changes during complete brain ischemia. The American Journal of Physiology. 250: R348-57. PMID 3082219 DOI: 10.1152/Ajpregu.1986.250.3.R348  1
1986 Kraig RP, Petito C, Plum F, Pulsinelli W. Hydrogen ions and ischemic brain damage Annals of the New York Academy of Sciences. 372-374. DOI: 10.1111/J.1749-6632.1986.Tb27168.X  1
1985 Kraig RP, Pulsinelli WA, Plum F. Hydrogen ion buffering during complete brain ischemia. Brain Research. 342: 281-90. PMID 4041829 DOI: 10.1016/0006-8993(85)91127-8  1
1985 Kraig RP, Pulsinelli WA, Plum F. Heterogeneous distribution of hydrogen and bicarbonate ions during complete brain ischemia. Progress in Brain Research. 63: 155-66. PMID 3835578 DOI: 10.1016/S0079-6123(08)61981-0  1
1985 Kraig RP, Pulsinelli WA, Plum F. Heterogeneous Distribution of Hydrogen and Bicarbonate Ions During Complete Brain Cischemia Progress in Brain Research. 63: 155-166. DOI: 10.1016/S0079-6123(08)61981-0  1
1983 Kraig RP, Ferreira Filho CR, Nicholson C. Alkaline and acid transients in cerebellar microenvironment Journal of Neurophysiology. 49: 831-850. PMID 6834101 DOI: 10.1152/Jn.1983.49.3.831  1
1978 Nicholson C, Kraig RP, ten Bruggencate G, Stöckle H, Steinberg R. Potassium, calcium, chloride and sodium changes in extracellular space during spreading depression in cerebellum [proceedings] Arzneimittel-Forschung/Drug Research. 28: 874-875. PMID 581976  1
1976 Kraig RP, Nicholson C. Sodium liquid ion exchanger microelectrode used to measure large extracellular sodium transients Science. 194: 725-726. PMID 982036 DOI: 10.1126/Science.982036  1
1975 Nicholson C, Kraig RP. Chloride and potassium changes measured during spreading depression in catfish cerebellum Brain Research. 96: 384-389. PMID 1175022 DOI: 10.1016/0006-8993(75)90752-0  1
1973 Mckelvey DR, Kraig RP, Zimmerman K, Ault A, Perfetti R. The nature of solvent participation in the restriction of rotation about single bonds. II Journal of Organic Chemistry. 38: 3610-3614.  1
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