David H. Gutmann - Publications

Biology and Biomedical Sciences (Neurosciences) Washington University, Saint Louis, St. Louis, MO 
Cell Biology, Oncology, Neuroscience Biology

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Year Citation  Score
2016 Li K, Turner AN, Chen M, Brosius SN, Schoeb TR, Messiaen LM, Bedwell DM, Zinn KR, Anastasaki C, Gutmann DH, Korf BR, Kesterson RA. Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I. Disease Models & Mechanisms. 9: 759-767. PMID 27482814 DOI: 10.1242/dmm.025783  0.36
2016 Smithson LJ, Gutmann DH. Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival. Genes & Development. 30: 1383-8. PMID 27340174 DOI: 10.1101/gad.279661.116  0.36
2016 Smithson LJ, Anastasaki C, Chen R, Toonen JA, Williams SB, Gutmann DH. Contextual signaling in cancer. Seminars in Cell & Developmental Biology. PMID 27269372 DOI: 10.1016/j.semcdb.2016.06.002  0.36
2016 Gutmann DH. Exploring the genetic basis for clinical variation in neurofibromatosis type 1. Expert Review of Neurotherapeutics. PMID 27171602 DOI: 10.1080/14737175.2016.1189329  0.36
2016 Johnson KJ, Zoellner NL, Gutmann DH. Peri-gestational risk factors for pediatric brain tumors in Neurofibromatosis Type 1. Cancer Epidemiology. 42: 53-59. PMID 27018750 DOI: 10.1016/j.canep.2016.03.005  0.36
2016 Chen YH, Cimino PJ, Luo J, Dahiya S, Gutmann DH. ABCG1 maintains high-grade glioma survival in vitro and in vivo. Oncotarget. PMID 26981778 DOI: 10.18632/oncotarget.8030  0.36
2016 Zafar R, Hsiao EY, Botteron KN, McKinstry RC, Gutmann DH. De novo development of gliomas in a child with neurofibromatosis type 1, fragile X and previously normal brain magnetic resonance imaging. Radiology Case Reports. 11: 33-5. PMID 26973730 DOI: 10.1016/j.radcr.2015.12.008  0.36
2016 Schwetye KE, Joseph NM, Al-Kateb H, Rich KM, Schmidt RE, Perry A, Gutmann DH, Dahiya S. Gliosarcomas lack BRAF(V600E) mutation, but a subset exhibit β-catenin nuclear localization. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 26932501 DOI: 10.1111/neup.12293  0.36
2016 Anderson DM, Van de Plas R, Rose KL, Hill S, Schey KL, Solga AC, Gutmann DH, Caprioli RM. 3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated optic glioma. Journal of Proteomics. PMID 26883872 DOI: 10.1016/j.jprot.2016.02.004  0.36
2016 Hirbe AC, Dahiya S, Friedmann-Morvinski D, Verma IM, Clapp DW, Gutmann DH. Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation. Oncotarget. PMID 26859681 DOI: 10.18632/oncotarget.7232  0.36
2015 Hambardzumyan D, Gutmann DH, Kettenmann H. The role of microglia and macrophages in glioma maintenance and progression. Nature Neuroscience. 19: 20-7. PMID 26713745 DOI: 10.1038/nn.4185  0.36
2015 Porcelli B, Zoellner NL, Abadin SS, Gutmann DH, Johnson KJ. Associations between allergic conditions and pediatric brain tumors in Neurofibromatosis type 1. Familial Cancer. PMID 26666764 DOI: 10.1007/s10689-015-9855-3  0.36
2015 Baker SJ, Ellison DW, Gutmann DH. Pediatric gliomas as neurodevelopmental disorders. Glia. PMID 26638183 DOI: 10.1002/glia.22945  0.36
2015 Solga AC, Pong WW, Kim KY, Cimino PJ, Toonen JA, Walker J, Wylie T, Magrini V, Griffith M, Griffith OL, Ly A, Ellisman MH, Mardis ER, Gutmann DH. RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth. Neoplasia (New York, N.Y.). 17: 776-88. PMID 26585233 DOI: 10.1016/j.neo.2015.10.002  0.36
2015 Anderson JL, Gutmann DH. Neurofibromatosis type 1. Handbook of Clinical Neurology. 132: 75-86. PMID 26564071 DOI: 10.1016/B978-0-444-62702-5.00004-4  0.36
2015 Chen YH, Gianino SM, Gutmann DH. Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways. Genes & Development. 29: 1677-82. PMID 26272820 DOI: 10.1101/gad.261677.115  0.36
2015 Abadin SS, Zoellner NL, Schaeffer M, Porcelli B, Gutmann DH, Johnson KJ. Racial/Ethnic Differences in Pediatric Brain Tumor Diagnoses in Patients with Neurofibromatosis Type 1. The Journal of Pediatrics. PMID 26028287 DOI: 10.1016/j.jpeds.2015.04.076  0.36
2015 Hirbe AC, Dahiya S, Miller CA, Li T, Fulton RS, Zhang X, McDonald S, DeSchryver K, Duncavage EJ, Walrath J, Reilly KM, Abel HJ, Pekmezci M, Perry A, Ley TJ, ... Gutmann DH, et al. Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25925892 DOI: 10.1158/1078-0432.CCR-14-3049  0.36
2015 Anastasaki C, Woo AS, Messiaen LM, Gutmann DH. Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning. Human Molecular Genetics. 24: 3518-28. PMID 25788518 DOI: 10.1093/hmg/ddv103  0.36
2015 Bender RH, Haigis KM, Gutmann DH. Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner. Stem Cells (Dayton, Ohio). 33: 1998-2010. PMID 25788415 DOI: 10.1002/stem.1990  0.36
2015 Chen YH, McGowan LD, Cimino PJ, Dahiya S, Leonard JR, Lee da Y, Gutmann DH. Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties. Cell Reports. 10: 1899-912. PMID 25772366 DOI: 10.1016/j.celrep.2015.02.041  0.36
2015 Brossier NM, Gutmann DH. Improving outcomes for neurofibromatosis 1-associated brain tumors. Expert Review of Anticancer Therapy. 15: 415-23. PMID 25652347 DOI: 10.1586/14737140.2015.1009043  0.36
2015 Ackerman SD, Garcia C, Piao X, Gutmann DH, Monk KR. The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA. Nature Communications. 6: 6122. PMID 25607772 DOI: 10.1038/ncomms7122  0.36
2015 Kaul A, Toonen JA, Cimino PJ, Gianino SM, Gutmann DH. Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth. Neuro-Oncology. 17: 843-53. PMID 25534823 DOI: 10.1093/neuonc/nou329  0.36
2015 Sharkey EK, Zoellner NL, Abadin S, Gutmann DH, Johnson KJ. Validity of participant-reported diagnoses in an online patient registry: a report from the NF1 Patient Registry Initiative. Contemporary Clinical Trials. 40: 212-7. PMID 25533730 DOI: 10.1016/j.cct.2014.12.006  0.36
2015 Gutmann DH. Microglia in the tumor microenvironment: taking their TOLL on glioma biology. Neuro-Oncology. 17: 171-3. PMID 25523594 DOI: 10.1093/neuonc/nou346  0.36
2015 Liu Q, Zoellner N, Gutmann DH, Johnson KJ. Parental age and Neurofibromatosis Type 1: a report from the NF1 Patient Registry Initiative. Familial Cancer. 14: 317-24. PMID 25523354 DOI: 10.1007/s10689-014-9774-8  0.36
2015 Epstein JA, Ingram DA, Hirbe AC, Gutmann DH. A multidisciplinary approach in neurofibromatosis 1-Authors' reply The Lancet Neurology. 14: 30-31. PMID 25496893 DOI: 10.1016/S1474-4422(14)70298-4  0.36
2015 Rauen KA, Huson SM, Burkitt-Wright E, Evans DG, Farschtschi S, Ferner RE, Gutmann DH, Hanemann CO, Kerr B, Legius E, Parada LF, Patton M, Peltonen J, Ratner N, Riccardi VM, et al. Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues. American Journal of Medical Genetics. Part A. 167: 1-10. PMID 25393061 DOI: 10.1002/ajmg.a.36793  0.36
2015 Warrington NM, Sun T, Luo J, McKinstry RC, Parkin PC, Ganzhorn S, Spoljaric D, Albers AC, Merkelson A, Stewart DR, Stevenson DA, Viskochil D, Druley TE, Forys JT, Reilly KM, ... ... Gutmann DH, et al. The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients. Cancer Research. 75: 16-21. PMID 25381154 DOI: 10.1158/0008-5472.CAN-14-1891  0.36
2015 Weiss B, Widemann BC, Wolters P, Dombi E, Vinks A, Cantor A, Perentesis J, Schorry E, Ullrich N, Gutmann DH, Tonsgard J, Viskochil D, Korf B, Packer RJ, Fisher MJ. Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a neurofibromatosis Clinical Trials Consortium phase II study. Neuro-Oncology. 17: 596-603. PMID 25314964 DOI: 10.1093/neuonc/nou235  0.36
2015 Solga AC, Pong WW, Walker J, Wylie T, Magrini V, Apicelli AJ, Griffith M, Griffith OL, Kohsaka S, Wu GF, Brody DL, Mardis ER, Gutmann DH. RNA-sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease. Glia. 63: 531-48. PMID 25258010 DOI: 10.1002/glia.22754  0.36
2015 Kaul A, Toonen JA, Gianino SM, Gutmann DH. The impact of coexisting genetic mutations on murine optic glioma biology. Neuro-Oncology. 17: 670-7. PMID 25246427 DOI: 10.1093/neuonc/nou287  0.36
2015 Pekmezci M, Reuss DE, Hirbe AC, Dahiya S, Gutmann DH, von Deimling A, Horvai AE, Perry A. Morphologic and immunohistochemical features of malignant peripheral nerve sheath tumors and cellular schwannomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 187-200. PMID 25189642 DOI: 10.1038/modpathol.2014.109  0.36
2015 Pachow D, Wick W, Gutmann DH, Mawrin C. The mTOR signaling pathway as a treatment target for intracranial neoplasms. Neuro-Oncology. 17: 189-99. PMID 25165193 DOI: 10.1093/neuonc/nou164  0.36
2015 Madubata CC, Olsen MA, Stwalley DL, Gutmann DH, Johnson KJ. Neurofibromatosis type 1 and chronic neurological conditions in the United States: an administrative claims analysis. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 17: 36-42. PMID 24901347 DOI: 10.1038/gim.2014.70  0.36
2015 Soucy EA, Wessel LE, Gao F, Albers AC, Gutmann DH, Dunn CM. A pilot study for evaluation of hypotonia in children with neurofibromatosis type 1. Journal of Child Neurology. 30: 382-5. PMID 24789516 DOI: 10.1177/0883073814531823  0.36
2015 Darken RS, Gutmann DH. Neuroibromatosis type I Molecular Oncology: Causes of Cancer and Targets For Treatment. 679-685. DOI: 10.1017/CBO9781139046947.061  0.36
2014 Gutmann DH. The taxonomy of brain cancer stem cells: what's in a name? Oncoscience. 1: 241-7. PMID 25594016 DOI: 10.18632/oncoscience.25  0.36
2014 Gutmann DH. NF GEMMs already! The power and promise of mouse tumor models. Cancer Cell. 26: 596-9. PMID 25517743 DOI: 10.1016/j.ccell.2014.10.007  0.36
2014 Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, et al. Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics. Part A. 164: 2969-78. PMID 25255738 DOI: 10.1002/ajmg.a.36754  0.36
2014 Huang YC, Wei KC, Chang CN, Chen PY, Hsu PW, Chen CP, Lu CS, Wang HL, Gutmann DH, Yeh TH. Transglutaminase 2 expression is increased as a function of malignancy grade and negatively regulates cell growth in meningioma. Plos One. 9: e108228. PMID 25247996 DOI: 10.1371/journal.pone.0108228  0.36
2014 Schwetye KE, Gutmann DH. Cognitive and behavioral problems in children with neurofibromatosis type 1: challenges and future directions. Expert Review of Neurotherapeutics. 14: 1139-52. PMID 25161109 DOI: 10.1586/14737175.2014.953931  0.36
2014 Hirbe AC, Gutmann DH. Neurofibromatosis type 1: a multidisciplinary approach to care. The Lancet. Neurology. 13: 834-43. PMID 25030515 DOI: 10.1016/S1474-4422(14)70063-8  0.36
2014 Gutmann DH. Eliminating barriers to personalized medicine: learning from neurofibromatosis type 1. Neurology. 83: 463-71. PMID 24975854 DOI: 10.1212/WNL.0000000000000652  0.36
2014 Weiss B, Widemann BC, Wolters P, Dombi E, Vinks AA, Cantor A, Korf B, Perentesis J, Gutmann DH, Schorry E, Packer R, Fisher MJ. Sirolimus for non-progressive NF1-associated plexiform neurofibromas: an NF clinical trials consortium phase II study. Pediatric Blood & Cancer. 61: 982-6. PMID 24851266 DOI: 10.1002/pbc.24873  0.36
2014 Garcia C, Gutmann DH. Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2-dependent manner. Plos One. 9: e97320. PMID 24817309 DOI: 10.1371/journal.pone.0097320  0.36
2014 Cabanski CR, Magrini V, Griffith M, Griffith OL, McGrath S, Zhang J, Walker J, Ly A, Demeter R, Fulton RS, Pong WW, Gutmann DH, Govindan R, Mardis ER, Maher CA. cDNA hybrid capture improves transcriptome analysis on low-input and archived samples. The Journal of Molecular Diagnostics : Jmd. 16: 440-51. PMID 24814956 DOI: 10.1016/j.jmoldx.2014.03.004  0.36
2014 Diggs-Andrews KA, Brown JA, Gianino SM, D'Agostino McGowan L, Rubin JB, Wozniak DF, Gutmann DH. Reply: To PMID 24375753. Annals of Neurology. 75: 800-1. PMID 24752946 DOI: 10.1002/ana.24156  0.36
2014 Fisher MJ, Loguidice M, Gutmann DH, Listernick R, Ferner RE, Ullrich NJ, Packer RJ, Tabori U, Hoffman RO, Ardern-Holmes SL, Hummel TR, Hargrave DR, Bouffet E, Charrow J, Bilaniuk LT, et al. Gender as a disease modifier in neurofibromatosis type 1 optic pathway glioma. Annals of Neurology. 75: 799-800. PMID 24740685 DOI: 10.1002/ana.24157  0.36
2014 Johnson KJ, Mueller NL, Williams K, Gutmann DH. Evaluation of participant recruitment methods to a rare disease online registry. American Journal of Medical Genetics. Part A. 164: 1686-94. PMID 24700441 DOI: 10.1002/ajmg.a.36530  0.36
2014 Kumar MG, Emnett RJ, Bayliss SJ, Gutmann DH. Glomus tumors in individuals with neurofibromatosis type 1. Journal of the American Academy of Dermatology. 71: 44-8. PMID 24685357 DOI: 10.1016/j.jaad.2014.01.913  0.36
2014 Gavilan HS, Kulikauskas RM, Gutmann DH, Fehon RG. In vivo functional analysis of the human NF2 tumor suppressor gene in Drosophila. Plos One. 9: e90853. PMID 24595234 DOI: 10.1371/journal.pone.0090853  0.36
2014 Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, ... Gutmann DH, et al. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. American Journal of Medical Genetics. Part A. 164: 563-78. PMID 24443315 DOI: 10.1002/ajmg.a.36312  0.36
2014 Gomez GG, Volinia S, Croce CM, Zanca C, Li M, Emnett R, Gutmann DH, Brennan CW, Furnari FB, Cavenee WK. Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity. Cancer Research. 74: 1429-39. PMID 24436148 DOI: 10.1158/0008-5472.CAN-13-2117  0.36
2014 Diggs-Andrews KA, Brown JA, Gianino SM, Rubin JB, Wozniak DF, Gutmann DH. Sex Is a major determinant of neuronal dysfunction in neurofibromatosis type 1. Annals of Neurology. 75: 309-16. PMID 24375753 DOI: 10.1002/ana.24093  0.36
2014 Hirbe AC, Pekmezci M, Dahiya S, Apicelli AJ, Van Tine BA, Perry A, Gutmann DH. BRAFV600E mutation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors. Neuro-Oncology. 16: 466-7. PMID 24366910 DOI: 10.1093/neuonc/not248  0.36
2014 Chen YH, Gutmann DH. The molecular and cell biology of pediatric low-grade gliomas Oncogene. 33: 2019-2026. PMID 23624918 DOI: 10.1038/onc.2013.148  0.36
2014 Solga AC, Gianino SM, Gutmann DH. NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma Oncogene. 33: 289-299. PMID 23318450 DOI: 10.1038/onc.2012.580  0.36
2014 Ostendorf AP, Gutmann DH. Neurofibromatoses Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 921-933. DOI: 10.1016/B978-0-12-410529-4.00079-6  0.36
2013 Hawasli AH, Rubin JB, Tran DD, Adkins DR, Waheed S, Hullar TE, Gutmann DH, Evans J, Leonard JR, Zipfel GJ, Chicoine MR. Antiangiogenic agents for nonmalignant brain tumors. Journal of Neurological Surgery. Part B, Skull Base. 74: 136-41. PMID 24436903 DOI: 10.1055/s-0033-1338262  0.36
2013 Fisher MJ, Avery RA, Allen JC, Ardern-Holmes SL, Bilaniuk LT, Ferner RE, Gutmann DH, Listernick R, Martin S, Ullrich NJ, Liu GT. Functional outcome measures for NF1-associated optic pathway glioma clinical trials. Neurology. 81: S15-24. PMID 24249802 DOI: 10.1212/01.wnl.0000435745.95155.b8  0.36
2013 Pong WW, Walker J, Wylie T, Magrini V, Luo J, Emnett RJ, Choi J, Cooper ML, Griffith M, Griffith OL, Rubin JB, Fuller GN, Piwnica-Worms D, Feng X, Hambardzumyan D, ... ... Gutmann DH, et al. F11R is a novel monocyte prognostic biomarker for malignant glioma. Plos One. 8: e77571. PMID 24147027 DOI: 10.1371/journal.pone.0077571  0.36
2013 Ostendorf AP, Gutmann DH, Weisenberg JL. Epilepsy in individuals with neurofibromatosis type 1. Epilepsia. 54: 1810-4. PMID 24032542 DOI: 10.1111/epi.12348  0.36
2013 Lin AL, Gutmann DH. Advances in the treatment of neurofibromatosis-associated tumours. Nature Reviews. Clinical Oncology. 10: 616-24. PMID 23939548 DOI: 10.1038/nrclinonc.2013.144  0.36
2013 Ferner RE, Gutmann DH. Neurofibromatosis type 1 (NF1): diagnosis and management. Handbook of Clinical Neurology. 115: 939-55. PMID 23931823 DOI: 10.1016/B978-0-444-52902-2.00053-9  0.36
2013 Kaul A, Chen YH, Emnett RJ, Gianino SM, Gutmann DH. Conditional KIAA1549:BRAF mice reveal brain region- and cell type-specific effects. Genesis (New York, N.Y. : 2000). 51: 708-16. PMID 23893969 DOI: 10.1002/dvg.22415  0.36
2013 Wozniak DF, Diggs-Andrews KA, Conyers S, Yuede CM, Dearborn JT, Brown JA, Tokuda K, Izumi Y, Zorumski CF, Gutmann DH. Motivational disturbances and effects of L-dopa administration in neurofibromatosis-1 model mice. Plos One. 8: e66024. PMID 23762458 DOI: 10.1371/journal.pone.0066024  0.36
2013 Ostendorf AP, McKinstry RC, Shimony JS, Gutmann DH. Teaching NeuroImages: T2 hyperintensities in neurofibromatosis type 1. Neurology. 80: e215-6. PMID 23671349 DOI: 10.1212/WNL.0b013e3182929f7c  0.36
2013 Ji J, Shimony J, Gao F, McKinstry RC, Gutmann DH. Optic nerve tortuosity in children with neurofibromatosis type 1. Pediatric Radiology. 43: 1336-43. PMID 23636538 DOI: 10.1007/s00247-013-2694-1  0.36
2013 O'Brien DE, Brenner DS, Gutmann DH, Gereau RW. Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1. The Journal of Pain : Official Journal of the American Pain Society. 14: 628-37. PMID 23578956 DOI: 10.1016/j.jpain.2013.01.770  0.36
2013 Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkinson DB, Weis J, Schröder JM, ... Gutmann DH, et al. Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy. Nature Neuroscience. 16: 426-33. PMID 23455610 DOI: 10.1038/nn.3348  0.36
2013 Gutmann DH, Blakeley JO, Korf BR, Packer RJ. Optimizing biologically targeted clinical trials for neurofibromatosis. Expert Opinion On Investigational Drugs. 22: 443-62. PMID 23425047 DOI: 10.1517/13543784.2013.772979  0.36
2013 Pong WW, Higer SB, Gianino SM, Emnett RJ, Gutmann DH. Reduced microglial CX3CR1 expression delays neurofibromatosis-1 glioma formation. Annals of Neurology. 73: 303-8. PMID 23424002 DOI: 10.1002/ana.23813  0.36
2013 Karasinska JM, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit JK, Stukas S, Lütjohann D, Gutmann DH, Wellington CL, Hayden MR. ABCA1 influences neuroinflammation and neuronal death. Neurobiology of Disease. 54: 445-55. PMID 23376685 DOI: 10.1016/j.nbd.2013.01.018  0.36
2013 Diggs-Andrews KA, Gutmann DH. Modeling cognitive dysfunction in neurofibromatosis-1. Trends in Neurosciences. 36: 237-47. PMID 23312374 DOI: 10.1016/j.tins.2012.12.002  0.36
2013 Gutmann DH, Avery R, Ferner RE, Listernick R. Visual function and optic pathway glioma: a critical response. Jama Ophthalmology. 131: 120-1. PMID 23307228 DOI: 10.1001/jamaophthalmol.2013.571  0.36
2013 Johnson KJ, Hussain I, Williams K, Santens R, Mueller NL, Gutmann DH. Development of an international internet-based neurofibromatosis Type 1 patient registry. Contemporary Clinical Trials. 34: 305-11. PMID 23246715 DOI: 10.1016/j.cct.2012.12.002  0.36
2013 Diggs-Andrews KA, Tokuda K, Izumi Y, Zorumski CF, Wozniak DF, Gutmann DH. Dopamine deficiency underlies learning deficits in neurofibromatosis-1 mice. Annals of Neurology. 73: 309-15. PMID 23225063 DOI: 10.1002/ana.23793  0.36
2013 Gutmann DH, McLellan MD, Hussain I, Wallis JW, Fulton LL, Fulton RS, Magrini V, Demeter R, Wylie T, Kandoth C, Leonard JR, Guha A, Miller CA, Ding L, Mardis ER. Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma. Genome Research. 23: 431-9. PMID 23222849 DOI: 10.1101/gr.142604.112  0.36
2013 Ho CY, Bar E, Giannini C, Marchionni L, Karajannis MA, Zagzag D, Gutmann DH, Eberhart CG, Rodriguez FJ. MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. Neuro-Oncology. 15: 69-82. PMID 23161775 DOI: 10.1093/neuonc/nos269  0.36
2013 Wessel LE, Gao F, Gutmann DH, Dunn CM. Longitudinal analysis of developmental delays in children with neurofibromatosis type 1. Journal of Child Neurology. 28: 1689-93. PMID 23112244 DOI: 10.1177/0883073812462885  0.36
2013 Wessel LE, Albers AC, Gutmann DH, Dunn CM. The association between hypotonia and brain tumors in children with neurofibromatosis type 1. Journal of Child Neurology. 28: 1664-7. PMID 23071069 DOI: 10.1177/0883073812460918  0.36
2013 Soucy EA, van Oppen D, Nejedly NL, Gao F, Gutmann DH, Hollander AS. Height assessments in children with neurofibromatosis type 1. Journal of Child Neurology. 28: 303-7. PMID 22752476 DOI: 10.1177/0883073812446310  0.36
2013 Isenberg JC, Templer A, Gao F, Titus JB, Gutmann DH. Attention skills in children with neurofibromatosis type 1. Journal of Child Neurology. 28: 45-9. PMID 22496119 DOI: 10.1177/0883073812439435  0.36
2013 Templer AK, Titus JB, Gutmann DH. A neuropsychological perspective on attention problems in neurofibromatosis type 1. Journal of Attention Disorders. 17: 489-96. PMID 22354384 DOI: 10.1177/1087054711433422  0.36
2013 Kaul A, Hussain I, Gutmann DH. Using genetically engineered mouse models to understand low-grade glioma development and growth in children Neuromethods. 77: 203-215. DOI: 10.1007/7657_2011_29  0.36
2012 Kaul A, Chen YH, Emnett RJ, Dahiya S, Gutmann DH. Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner. Genes & Development. 26: 2561-6. PMID 23152448 DOI: 10.1101/gad.200907.112  0.36
2012 Gutmann DH, Parada LF, Silva AJ, Ratner N. Neurofibromatosis type 1: modeling CNS dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14087-93. PMID 23055477 DOI: 10.1523/JNEUROSCI.3242-12.2012  0.36
2012 Acosta MT, Bearden CE, Castellanos FX, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, et al. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. American Journal of Medical Genetics. Part A. 158: 2225-32. PMID 22821737 DOI: 10.1002/ajmg.a.35535  0.36
2012 Lee da Y, Gianino SM, Gutmann DH. Innate neural stem cell heterogeneity determines the patterning of glioma formation in children. Cancer Cell. 22: 131-8. PMID 22789544 DOI: 10.1016/j.ccr.2012.05.036  0.36
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. Development (Cambridge, England). 139: 2477-87. PMID 22675209 DOI: 10.1242/dev.077214  0.36
2012 Fisher MJ, Loguidice M, Gutmann DH, Listernick R, Ferner RE, Ullrich NJ, Packer RJ, Tabori U, Hoffman RO, Ardern-Holmes SL, Hummel TR, Hargrave DR, Bouffet E, Charrow J, Bilaniuk LT, et al. Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis. Neuro-Oncology. 14: 790-7. PMID 22474213 DOI: 10.1093/neuonc/nos076  0.36
2012 Jost S, Gutmann DH. Neurofibromatosis and other genetic syndromes. Handbook of Clinical Neurology. 105: 569-82. PMID 22230519 DOI: 10.1016/B978-0-444-53502-3.00009-4  0.36
2012 Weber JD, Gutmann DH. Deconvoluting mTOR biology. Cell Cycle (Georgetown, Tex.). 11: 236-48. PMID 22214661 DOI: 10.4161/cc.11.2.19022  0.36
2012 Soucy EA, Gao F, Gutmann DH, Dunn CM. Developmental delays in children with neurofibromatosis type 1. Journal of Child Neurology. 27: 641-4. PMID 22190506 DOI: 10.1177/0883073811423974  0.36
2012 Brown JA, Diggs-Andrews KA, Gianino SM, Gutmann DH. Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner. Molecular and Cellular Neurosciences. 49: 13-22. PMID 21903164 DOI: 10.1016/j.mcn.2011.08.008  0.36
2012 Thangarajh M, Gutmann DH. Low-grade gliomas as neurodevelopmental disorders: Insights from mouse models of neurofibromatosis-1 Neuropathology and Applied Neurobiology. 38: 241-253. DOI: 10.1111/j.1365-2990.2011.01230.x  0.36
2012 Solga AC, Gutmann DH. NF1-associated optic glioma Neurofibromatosis Type 1: Molecular and Cellular Biology. 2147483647: 341-352. DOI: 10.1007/978-3-642-32864-0_22  0.36
2011 Brown JA, Xu J, Diggs-Andrews KA, Wozniak DF, Mach RH, Gutmann DH. PET imaging for attention deficit preclinical drug testing in neurofibromatosis-1 mice. Experimental Neurology. 232: 333-8. PMID 21963652 DOI: 10.1016/j.expneurol.2011.09.005  0.36
2011 Dahiya S, Lee DY, Gutmann DH. Comparative characterization of the human and mouse third ventricle germinal zones Journal of Neuropathology and Experimental Neurology. 70: 622-633. PMID 21666496 DOI: 10.1097/NEN.0b013e31822200aa  0.36
2011 Crouse NR, Dahiya S, Gutmann DH. Rethinking Pediatric Gliomas as Developmental Brain Abnormalities Current Topics in Developmental Biology. 94: 283-308. PMID 21295690 DOI: 10.1016/B978-0-12-380916-2.00009-7  0.36
2011 Gutmann DH, Listernick R, Ferner RE. Screening for symptomatic optic pathway glioma in children with neurofibromatosis type 1 Eye. 25: 818. PMID 21274014 DOI: 10.1038/eye.2010.227  0.36
2011 Banerjee S, Gianino SM, Gao F, Christians U, Gutmann DH. Interpreting mammalian target of rapamycin and cell growth inhibition in a genetically engineered mouse model of Nf1-deficient astrocytes. Molecular Cancer Therapeutics. 10: 279-91. PMID 21216928 DOI: 10.1158/1535-7163.MCT-10-0654  0.36
2011 Pong WW, Gutmann DH. The ecology of brain tumors: Lessons learned from neurofibromatosis-1 Oncogene. 30: 1135-1146. PMID 21076468 DOI: 10.1038/onc.2010.519  0.36
2011 Wang L, Gutmann DH, Roos RP. Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice. Human Molecular Genetics. 20: 286-93. PMID 20962037 DOI: 10.1093/hmg/ddq463  0.36
2011 Hussain I, Gutmann DH. Molecular genetics of optic glioma: Lessons learned from neurofibromatosis-1 genetically engineered mice Expert Review of Ophthalmology. 6: 363-369. DOI: 10.1586/eop.11.31  0.36
2010 Kim KY, Ju WK, Hegedus B, Gutmann DH, Ellisman MH. Ultrastructural characterization of the optic pathway in a mouse model of neurofibromatosis-1 optic glioma. Neuroscience. 170: 178-88. PMID 20600672 DOI: 10.1016/j.neuroscience.2010.06.017  0.36
2010 Brown JA, Gianino SM, Gutmann DH. Defective cAMP generation underlies the sensitivity of CNS neurons to neurofibromatosis-1 heterozygosity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5579-89. PMID 20410111 DOI: 10.1523/JNEUROSCI.3994-09.2010  0.36
2010 Claus EB, Gutmann DH, Gilbertson RJ. Response Journal of Neurosurgery: Spine. 12: 116. DOI: 10.3171/2009.8.SPINE09608  0.36
2009 Yeh TH, Lee DY, Gianino SM, Gutmann DH. Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation Glia. 57: 1239-1249. PMID 19191334 DOI: 10.1002/glia.20845  0.36
2009 Houshmandi SS, Emnett RJ, Giovannini M, Gutmann DH. The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner. Molecular and Cellular Biology. 29: 1472-86. PMID 19103750 DOI: 10.1128/MCB.01392-08  0.36
2009 Gutmann DH. Modeling human brain tumors in mice Brain Pathology. 19: 108-111. PMID 19076775 DOI: 10.1111/j.1750-3639.2008.00232.x  0.36
2008 Gutmann DH. Using neurofibromatosis-1 to better understand and treat pediatric low-grade glioma Journal of Child Neurology. 23: 1186-1194. PMID 18952585 DOI: 10.1177/0883073808321061  0.36
2008 Zeng LH, Xu L, Gutmann DH, Wong M. Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex Annals of Neurology. 63: 444-453. PMID 18389497 DOI: 10.1002/ana.21331  0.36
2007 Lee DY, Gutmann DH. Cancer stem cells and brain tumors: Uprooting the bad seeds Expert Review of Anticancer Therapy. 7: 1581-1590. PMID 18020926 DOI: 10.1586/14737140.7.11.1581  0.36
2007 Houshmandi SS, Gutmann DH. All in the family: using inherited cancer syndromes to understand de-regulated cell signaling in brain tumors. Journal of Cellular Biochemistry. 102: 811-9. PMID 17721931 DOI: 10.1002/jcb.21506  0.36
2007 Leonard JR, Ferner RE, Thomas N, Gutmann DH. Cervical cord compression from plexiform neurofibromas in neurofibromatosis 1 Journal of Neurology, Neurosurgery and Psychiatry. 78: 1404-1406. PMID 17635968 DOI: 10.1136/jnnp.2007.121509  0.36
2007 Gilbertson RJ, Gutmann DH. Tumorigenesis in the brain: Location, location, location Cancer Research. 67: 5579-5582. PMID 17575119 DOI: 10.1158/0008-5472.CAN-07-0760  0.36
2007 Sandsmark DK, Zhang H, Hegedus B, Pelletier CL, Weber JD, Gutmann DH. Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes. Cancer Research. 67: 4790-9. PMID 17510408 DOI: 10.1158/0008-5472.CAN-06-4470  0.36
2007 Sandsmark DK, Pelletier C, Weber JD, Gutmann DH. Mammalian target of rapamycin: master regulator of cell growth in the nervous system. Histology and Histopathology. 22: 895-903. PMID 17503347  0.36
2007 Daginakatte GC, Gutmann DH. Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth. Human Molecular Genetics. 16: 1098-112. PMID 17400655 DOI: 10.1093/hmg/ddm059  0.36
2007 Listernick R, Ferner RE, Liu GT, Gutmann DH. Optic pathway gliomas in neurofibromatosis-1: Controversies and recommendations Annals of Neurology. 61: 189-198. PMID 17387725 DOI: 10.1002/ana.21107  0.36
2007 Banerjee D, Hegedus B, Gutmann DH, Garbow JR. Detection and measurement of neurofibromatosis-1 mouse optic glioma in vivo. Neuroimage. 35: 1434-7. PMID 17383899 DOI: 10.1016/j.neuroimage.2007.02.019  0.36
2007 Su W, Xing R, Guha A, Gutmann DH, Sherman LS. Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging. Glia. 55: 723-33. PMID 17348023 DOI: 10.1002/glia.20501  0.36
2007 Piersall L, Gutmann DH. Neurofibromatosis 1 Neurobiology of Disease. 413-423. DOI: 10.1016/B978-012088592-3/50039-6  0.36
2006 Houshmandi SS, Surace EI, Zhang HB, Fuller GN, Gutmann DH. Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor. Neurology. 67: 1863-6. PMID 17130425 DOI: 10.1212/01.wnl.0000244472.56198.84  0.36
2006 Read TA, Hegedus B, Wechsler-Reya R, Gutmann DH. The neurobiology of neurooncology. Annals of Neurology. 60: 3-11. PMID 16802285 DOI: 10.1002/ana.20912  0.36
2006 Gerber MA, Bahr SM, Gutmann DH. Protein 4.1B/differentially expressed in adenocarcinoma of the lung-1 functions as a growth suppressor in meningioma cells by activating Rac1-dependent c-Jun-NH(2)-kinase signaling. Cancer Research. 66: 5295-303. PMID 16707455 DOI: 10.1158/0008-5472.CAN-05-1628  0.36
2006 Gutmann DH, Hunter-Schaedle K, Shannon KM. Harnessing preclinical mouse models to inform human clinical cancer trials. The Journal of Clinical Investigation. 116: 847-52. PMID 16585951 DOI: 10.1172/JCI28271  0.36
2006 Gutmann DH, Maher EA, Van Dyke T. Mouse models of human cancers consortium workshop on nervous system tumors Cancer Research. 66: 10-13. PMID 16397207 DOI: 10.1158/0008-5472.CAN-05-3180  0.36
2006 Esper GJ, Gutmann DH. Neurofibromatosis 1 and 2 Principles of Molecular Medicine. 1160-1164. DOI: 10.1007/978-1-59259-963-9_121  0.36
2005 Jansen LA, Uhlmann EJ, Crino PB, Gutmann DH, Wong M. Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes. Epilepsia. 46: 1871-80. PMID 16393152 DOI: 10.1111/j.1528-1167.2005.00289.x  0.36
2005 Dasgupta B, Yi Y, Hegedus B, Weber JD, Gutmann DH. Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma. Cancer Research. 65: 9843-50. PMID 16267007 DOI: 10.1158/0008-5472.CAN-05-1842  0.36
2005 Sharma MK, Zehnbauer BA, Watson MA, Gutmann DH. RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma. Neurology. 65: 1335-6. PMID 16247081 DOI: 10.1212/01.wnl.0000180409.78098.d7  0.36
2005 Scoles DR, Qin Y, Nguyen V, Gutmann DH, Pulst SM. HRS inhibits EGF receptor signaling in the RT4 rat schwannoma cell line. Biochemical and Biophysical Research Communications. 335: 385-92. PMID 16083858 DOI: 10.1016/j.bbrc.2005.07.083  0.36
2005 Rubin JB, Gutmann DH. Neurofibromatosis type 1 - a model for nervous system tumour formation? Nature Reviews. Cancer. 5: 557-64. PMID 16069817 DOI: 10.1038/nrc1653  0.36
2005 Dasgupta B, Gutmann DH. Neurofibromin regulates neural stem cell proliferation, survival, and astroglial differentiation in vitro and in vivo Journal of Neuroscience. 25: 5584-5594. PMID 15944386 DOI: 10.1523/JNEUROSCI.4693-04.2005  0.36
2005 Perry A, Lusis EA, Gutmann DH. Meningothelial hyperplasia: A detailed clinicopathologic, immunohistochemical and genetic study of 11 cases Brain Pathology. 15: 109-115. PMID 15912882  0.36
2005 Ess KC, Kamp CA, Tu BP, Gutmann DH. Developmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complex. Neurology. 64: 1446-9. PMID 15851742 DOI: 10.1212/01.WNL.0000158653.81008.49  0.36
2005 Dasgupta B, Yi Y, Chen DY, Weber JD, Gutmann DH. Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors. Cancer Research. 65: 2755-60. PMID 15805275 DOI: 10.1158/0008-5472.CAN-04-4058  0.36
2005 Ward BA, Gutmann DH. Neurofibromatosis 1: From lab bench to clinic Pediatric Neurology. 32: 221-228. PMID 15797177 DOI: 10.1016/j.pediatrneurol.2004.11.002  0.36
2005 Rajaram V, Gutmann DH, Prasad SK, Mansur DB, Perry A. Alterations of protein 4.1 family members in ependymomas: a study of 84 cases. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 991-7. PMID 15731777 DOI: 10.1038/modpathol.3800390  0.36
2005 Dasgupta B, Li W, Perry A, Gutmann DH. Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes Cancer Research. 65: 236-245. PMID 15665300  0.36
2004 Perry A, Gutmann DH, Reifenberger G. Molecular pathogenesis of meningiomas Journal of Neuro-Oncology. 70: 183-202. PMID 15674477 DOI: 10.1007/s11060-004-2749-0  0.36
2004 Rong R, Tang X, Gutmann DH, Ye K. Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L. Proceedings of the National Academy of Sciences of the United States of America. 101: 18200-5. PMID 15598747 DOI: 10.1073/pnas.0405971102  0.36
2004 Scheidenhelm DK, Gutmann DH. Mouse models of tuberous sclerosis complex Journal of Child Neurology. 19: 726-733. PMID 15563020  0.36
2004 Maria BL, Deidrick KM, Roach ES, Gutmann DH. Tuberous sclerosis complex: Pathogenesis, diagnosis, strategies, therapies, and future research directions Journal of Child Neurology. 19: 632-642. PMID 15563008  0.36
2004 Lusis E, Gutmann DH. Meningioma: An update Current Opinion in Neurology. 17: 687-692. PMID 15542977 DOI: 10.1097/00019052-200412000-00008  0.36
2004 Surace EI, Lusis E, Haipek CA, Gutmann DH. Functional significance of S6K overexpression in meningioma progression Annals of Neurology. 56: 295-298. PMID 15293284 DOI: 10.1002/ana.20201  0.36
2004 Robb VA, Li W, Gutmann DH. Disruption of 14-3-3 binding does not impair Protein 4.1B growth suppression Oncogene. 23: 3589-3596. PMID 15116094 DOI: 10.1038/sj.onc.1207445  0.36
2004 Arun D, Gutmann DH. Recent advances in neurofibromatosis type 1 Current Opinion in Neurology. 17: 101-105. PMID 15021234 DOI: 10.1097/00019052-200404000-00004  0.36
2004 Spritz RA, Itin PH, Gutmann DH. Piebaldism and Neurofibromatosis Type 1: Horses of Very Different Colors Journal of Investigative Dermatology. 122: xxxiv-xxxv. PMID 15009761 DOI: 10.1046/j.0022-202X.2004.22235.x  0.36
2004 Surace EI, Haipek CA, Gutmann DH. Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function Oncogene. 23: 580-587. PMID 14724586 DOI: 10.1038/sj.onc.1207142  0.36
2003 Dasgupta B, Dugan LL, Gutmann DH. The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8949-54. PMID 14523097  0.36
2003 King A, Listernick R, Charrow J, Piersall L, Gutmann DH. Optic pathway gliomas in neurofibromatosis type 1: The effect of presenting symptoms on outcome American Journal of Medical Genetics. 122: 95-99. PMID 12955759  0.36
2003 Gutmann DH, Baker SJ, Giovannini M, Garbow J, Weiss W. Mouse models of human cancer consortium symposium on nervous system tumors. Cancer Research. 63: 3001-4. PMID 12782610  0.36
2003 Huang ZY, Wu Y, Burke SP, Gutmann DH. The 43000 growth-associated protein functions as a negative growth regulator in glioma. Cancer Research. 63: 2933-9. PMID 12782600  0.36
2003 Dasgupta B, Gutmann DH. Neurofibromatosis 1: Closing the GAP between mice and men Current Opinion in Genetics and Development. 13: 20-27. PMID 12573431 DOI: 10.1016/S0959-437X(02)00015-1  0.36
2003 Baser ME, R Evans DG, Gutmann DH. Neurofibromatosis 2. Current Opinion in Neurology. 16: 27-33. PMID 12544854 DOI: 10.1097/01.wco.0000053583.70044.ab  0.36
2003 Huang Zy, Wu Y, Hedrick N, Gutmann DH. T-cadherin-mediated cell growth regulation involves G2 phase arrest and requires p21CIP1/WAF1 expression Molecular and Cellular Biology. 23: 566-578. PMID 12509455 DOI: 10.1128/MCB.23.2.566-578.2003  0.36
2002 Gutmann DH. Neurofibromin in the brain Journal of Child Neurology. 17: 592-601. PMID 12403558  0.36
2002 Gutmann DH, Giovannini M. Mouse models of neurofibromatosis 1 and 2 Neoplasia. 4: 279-290. PMID 12082543 DOI: 10.1038/sj.neo.7900249  0.36
2002 Singh PK, Gutmann DH, Fuller CE, Newsham IF, Perry A. Differential involvement of protein 4.1 family members DAL-1 and NF2 in intracranial and intraspinal ependymomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 15: 526-31. PMID 12011257 DOI: 10.1038/modpathol.3880558  0.36
2002 Ferner RE, Gutmann DH. International consensus statement on malignant peripheral nerve sheath tumors in neurofibromatosis Cancer Research. 62: 1573-1577. PMID 11894862  0.36
2002 Huang ZY, Baldwin RL, Hedrick NM, Gutmann DH. Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo. Oncogene. 21: 1325-34. PMID 11857076 DOI: 10.1038/sj.onc.1205206  0.36
2002 Sun CX, Robb VA, Gutmann DH. Protein 4.1 tumor suppressors: Getting a FERM grip on growth regulation Journal of Cell Science. 115: 3991-4000. DOI: 10.1242/jcs.00094  0.36
2001 Sherman LS, Gutmann DH. Merlin: hanging tumor suppression on the Rac. Trends in Cell Biology. 11: 442-4. PMID 11684412 DOI: 10.1016/S0962-8924(01)02128-6  0.36
2001 Listernick R, Charrow J, Gutmann DH. Comments on neurofibromatosis 1 and optic pathway tumors [1] American Journal of Medical Genetics. 102: 105. PMID 11471182 DOI: 10.1002/1096-8628(20010722)102:1<105::AID-AJMG1395>3.0.CO;2-C  0.36
2001 Gutmann DH, Hirbe AC, Haipek CA. Functional analysis of neurofibromatosis 2 (NF2) missense mutations Human Molecular Genetics. 10: 1519-1529. PMID 11448944  0.36
2001 Scherer SS, Xu T, Crino P, Arroyo EJ, Gutmann DH. Ezrin, radixin, and moesin are components of Schwann cell microvilli. Journal of Neuroscience Research. 65: 150-64. PMID 11438984 DOI: 10.1002/jnr.1138  0.36
2001 MacCollin M, Gutmann DH, Korf B, Finkelstein R. Establishing priorities in neurofibromatosis research: A workshop summary Genetics in Medicine. 3: 212-217. PMID 11388764  0.36
2001 Gutmann DH, Hirbe AC, Huang ZY, Haipek CA. The Protein 4.1 tumor suppressor, DAL-1, impairs cell motility, but regulates proliferation in a cell-type-specific fashion Neurobiology of Disease. 8: 266-278. PMID 11300722 DOI: 10.1006/nbdi.2000.0376  0.36
2001 Li J, Perry A, James CD, Gutmann DH. Cancer-related gene expression profiles in NF1-associated pilocytic astrocytomas Neurology. 56: 885-890. PMID 11294925  0.36
2001 Reed N, Gutmann DH. Tumorigenesis in neurofibromatosis: New insights and potential therapies Trends in Molecular Medicine. 7: 157-162. PMID 11286939 DOI: 10.1016/S1471-4914(01)01955-4  0.36
2001 Gutmann DH. The neurofibromatoses: When less is more Human Molecular Genetics. 10: 747-755. PMID 11257108  0.36
2001 Uhlmann EJ, Gutmann DH. Tumor suppressor gene regulation of cell growth: Recent insights into neurofibromatosis 1 and 2 gene function Cell Biochemistry and Biophysics. 34: 61-78. DOI: 10.1385/CBB:34:1:61  0.36
2000 King AA, Debaun MR, Riccardi VM, Gutmann DH. Malignant peripheral nerve sheath tumors in neurofibromatosis 1 American Journal of Medical Genetics. 93: 388-392. PMID 10951462 DOI: 10.1002/1096-8628(20000828)93:5<388::AID-AJMG8>3.0.CO;2-#  0.36
2000 Gutmann DH, Donahoe J, Brown T, James CD, Perry A. Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas Neuropathology and Applied Neurobiology. 26: 361-367. PMID 10931370 DOI: 10.1046/j.1365-2990.2000.00258.x  0.36
2000 Waggoner DJ, Towbin J, Gottesman G, Gutmann DH. Clinic-based study of plexiform neurofibromas in neurofibromatosis 1 American Journal of Medical Genetics. 92: 132-135. PMID 10797438 DOI: 10.1002/(SICI)1096-8628(20000515)92:2<132::AID-AJMG10>3.0.CO;2-6  0.36
2000 King A, Gutmann DH. The question of familial meningiomas and schwannomas: NF2B or not to be? Neurology. 54: 4-5. PMID 10636116  0.36
1999 Gutmann DH, Haipek CA, Lu KH. Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations Journal of Neuroscience Research. 58: 706-716. PMID 10561699 DOI: 10.1002/(SICI)1097-4547(19991201)58:5<706::AID-JNR12>3.0.CO;2-Z  0.36
1999 Gutmann DH. Learning disabilities in neurofibromatosis 1: Sizing up the brain Archives of Neurology. 56: 1322-1323. PMID 10555648 DOI: 10.1001/archneur.56.11.1322  0.36
1999 Gutmann DH, Zhang Y, Hirbe A. Developmental regulation of a neuron-specific neurofibromatosis 1 isoform Annals of Neurology. 46: 777-782. PMID 10553997 DOI: 10.1002/1531-8249(199911)46:5<777::AID-ANA15>3.0.CO;2-H  0.36
1999 Liapis H, Dehner LP, Gutmann DH. Neurofibroma and cellular neurofibroma with atypia: a report of 14 tumors. The American Journal of Surgical Pathology. 23: 1156-8. PMID 10478679  0.36
1999 Listernick R, Charrow J, Gutmann DH. Intracranial gliomas in neurofibromatosis type 1 American Journal of Medical Genetics - Seminars in Medical Genetics. 89: 38-44. PMID 10469435 DOI: 10.1002/(SICI)1096-8628(19990326)89:1<38::AID-AJMG8>3.0.CO;2-M  0.36
1998 Gutmann DH. Parallels between tuberous sclerosis complex and neurofibromatosis 1: Common threads in the same tapestry Seminars in Pediatric Neurology. 5: 276-286. PMID 9874855 DOI: 10.1016/S1071-9091(98)80006-5  0.36
1998 Feldkamp MM, Gutmann DH, Guha A. Neurofibromatosis type 1: piecing the puzzle together. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 25: 181-91. PMID 9706718  0.36
1998 Gutmann DH. Recent insights into neurofibromatosis type 1: Clear genetic progress Archives of Neurology. 55: 778-780. PMID 9626767 DOI: 10.1001/archneur.55.6.778  0.36
1998 Xu HM, Gutmann DH. Merlin differentially associates with the microtubule and actin cytoskeleton Journal of Neuroscience Research. 51: 403-415. PMID 9486775 DOI: 10.1002/(SICI)1097-4547(19980201)51:3<403::AID-JNR13>3.0.CO;2-7  0.36
1998 Gutmann DH. The diagnosis and management of neurofibromatosis Neurologist. 4: 313-326.  0.36
1997 Levy CE, Krietemeyer L, Gutmann DH. Physiatry and care of patients with neurofibromatosis [5] (multiple letters) Journal of the American Medical Association. 278: 1493-1494. PMID 9363966  0.36
1997 Saporito-Irwin SM, Geist T, Gutmann DH. Ammonium acetate protocol for the preparation of plasmid DNA suitable for mammalian cell transfections Biotechniques. 23: 424-427. PMID 9298211  0.36
1997 Gutmann DH, Giordano MJ, Fishback AS, Guha A. Loss of merlin expression in sporadic meningiomas, ependymomas and schwannomas Neurology. 49: 267-270. PMID 9222206  0.36
1997 Xu HM, Gutmann DH. Mutations in the GAP-related domain impair the ability of neurofibromin to associate with microtubules Brain Research. 759: 149-152. PMID 9219873 DOI: 10.1016/S0006-8993(97)00328-4  0.36
1997 Gutmann DH. Molecular insights into neurofibromatosis 2 Neurobiology of Disease. 3: 247-261. PMID 9173923 DOI: 10.1006/nbdi.1997.0128  0.36
1997 Listernick R, Louis DN, Packer RJ, Gutmann DH. Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force. Annals of Neurology. 41: 143-9. PMID 9029062 DOI: 10.1002/ana.410410204  0.36
1996 Geist RT, Reddy AJ, Zhang J, Gutmann DH. Expression of the tuberous sclerosis 2 gene product, tuberin, in adult and developing nervous system tissues. Neurobiology of Disease. 3: 111-20. PMID 9173918 DOI: 10.1006/nbdi.1996.0011  0.36
1996 Scherer SS, Gutmann DH. Expression of the neurofibromatosis 2 tumor suppressor gene product, merlin, in Schwann cells. Journal of Neuroscience Research. 46: 595-605. PMID 8951671 DOI: 10.1002/(SICI)1097-4547(19961201)46:5<595::AID-JNR8>3.0.CO;2-E  0.36
1996 Gutmann DH, Gurney JG, Shannon KM, Zvulunov A. Juvenile xanthogranuloma, neurofibromatosis 1, and juvenile chronic myeloid leukemia [4] Archives of Dermatology. 132: 1390-1391. PMID 8915325 DOI: 10.1001/archderm.132.11.1390  0.36
1996 McDonald JW, Bautista RE, Gutmann DH. Pseudocervical cord syndrome: a deceptive flumazenil reversible manifestation of hepatic encephalopathy. Archives of Neurology. 53: 956. PMID 8859053  0.36
1996 Geist RT, Gutmann DH. Expression of a developmentally-regulated neuron-specific isoform of the neurofibromatosis 1 (NF1) gene Neuroscience Letters. 211: 85-88. PMID 8830850 DOI: 10.1016/0304-3940(96)12730-0  0.36
1996 Norton KK, Mahadeo DK, Geist RT, Gutmann DH. Expression of the neurofibromatosis 1 (NF1) gene during growth arrest. Neuroreport. 7: 601-4. PMID 8730839  0.36
1996 Platten M, Giordano MJ, Dirven CM, Gutmann DH, Louis DN. Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas. The American Journal of Pathology. 149: 621-7. PMID 8702000  0.36
1995 Norton KK, Xu J, Gutmann DH. Expression of the neurofibromatosis I gene product, neurofibromin, in blood vessel endothelial cells and smooth muscle. Neurobiology of Disease. 2: 13-21. PMID 8980005 DOI: 10.1006/nbdi.1995.0002  0.36
1995 Gutmann DH. Tumor suppressor genes as negative growth regulators in development and differentiation International Journal of Developmental Biology. 39: 895-907. PMID 8901192  0.36
1995 Geist RT, Gutmann DH. The tuberous sclerosis 2 gene is expressed at high levels in the cerebellum and developing spinal cord Cell Growth and Differentiation. 6: 1477-1483. PMID 8562486  0.36
1995 Gutmann DH, Wright DE, Geist RT, Snider WD. Expression of the neurofibromatosis 2 (NF2) gene isoforms during rat embryonic development. Human Molecular Genetics. 4: 471-8. PMID 7795605 DOI: 10.1093/hmg/4.3.471  0.36
1995 Gutmann DH, Geist RT, Wright DE, Snider WD. Expression of the neurofibromatosis 1 (NF1) isoforms in developing and adult rat tissues. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 6: 315-23. PMID 7794799  0.36
1995 Gutmann DH, Geist RT, Rose K, Wright DE. Expression of two new protein isoforms of the neurofibromatosis type 1 gene product, neurofibromin, in muscle tissues. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 202: 302-11. PMID 7780179 DOI: 10.1002/aja.1002020309  0.36
1995 Norton KK, Carey JC, Gutmann DH. Oculodentodigital dysplasia with cerebral white matter abnormalities in a two-generation family. American Journal of Medical Genetics. 57: 458-61. PMID 7677152 DOI: 10.1002/ajmg.1320570320  0.36
1995 Hewett SJ, Choi DW, Gutmann DH. Expression of the neurofibromatosis 1 (NF1) gene in reactive astrocytes in vitro. Neuroreport. 6: 1565-8. PMID 7579150  0.36
1995 Gutmann DH, Cole JL, Collins FS. Expression of the neurofibromatosis type 1 (NF1) gene during mouse embryonic development. Progress in Brain Research. 105: 327-35. PMID 7568895  0.36
1994 Boyer MJ, Gutmann DH, Collins FS, Bar-Sagi D. Crosslinking of the surface immunoglobulin receptor in B lymphocytes induces a redistribution of neurofibromin but not p120-GAP Oncogene. 9: 349-357. PMID 8290249  0.36
1994 Gutmann DH, Cole JL, Collins FS. Modulation of neurofibromatosis type 1 gene expression during in vitro myoblast differentiation. Journal of Neuroscience Research. 37: 398-405. PMID 8176761 DOI: 10.1002/jnr.490370312  0.36
1994 Gutmann DH. New insights into the neurofibromatoses Current Opinion in Neurology. 7: 166-171. PMID 8019663  0.36
1993 Gutmann DH, Collins FS. The neurofibromatosis type 1 gene and its protein product, neurofibromin Neuron. 10: 335-343. PMID 8461130 DOI: 10.1016/0896-6273(93)90324-K  0.36
1993 Gutmann DH, Collins FS. Neurofibromatosis Type 1: Beyond Positional Cloning Archives of Neurology. 50: 1185-1193. PMID 8215978 DOI: 10.1001/archneur.1993.00540110065007  0.36
1992 Gutmann DH, Collins FS. Recent progress toward understanding the molecular biology of von Recklinghausen neurofibromatosis Annals of Neurology. 31: 555-561. PMID 1596091  0.36
1992 Gutmann DH, Zackai EH, Emanuel BS. Congenital nystagmus in a [46,XX/45,X] mosaic woman from a family with X- linked congenital nystagmus [3] American Journal of Medical Genetics. 43: 897. DOI: 10.1002/ajmg.1320430531  0.36
1991 Gutmann DH, Wardinsky TD, Pagon RA, Weinberger E, Clarren SK. Chromosome 11q23.3-qter deletion and Alexander disease [3] American Journal of Medical Genetics. 39: 226-227. PMID 2063930  0.36
1991 Gutmann DH, Wood DL, Collins FS. Identification of the neurofibromatosis type 1 gene product Proceedings of the National Academy of Sciences of the United States of America. 88: 9658-9662. PMID 1946382  0.36
1991 Yousem DM, Gutmann DH, Milestone BN, Lenkinski RE. Integrated MR imaging and proton nuclear magnetic resonance spectroscopy in a family with an X-linked spastic paraparesis American Journal of Neuroradiology. 12: 785-789. PMID 1882768  0.36
1991 Gutmann DH, Marino PL. An alternative apnea test for the evaluation of brain death [3] Annals of Neurology. 30: 852-853. PMID 1789700  0.36
1990 Gutmann DH, Fischbeck KH, Kamholz J. Complicated hereditary spastic paraparesis with cerebral white matter lesions. American Journal of Medical Genetics. 36: 251-7. PMID 2368815 DOI: 10.1002/ajmg.1320360222  0.36
1990 Gutmann DH, Grossman RI, Mollman JE. Personality changes associated with thalamic infiltration Journal of Neuro-Oncology. 8: 263-267. PMID 2358857 DOI: 10.1007/BF00177359  0.36
1990 Gutmann DH, Cantor CR, Piacente GJ, McCluskey LF. Cerebral vasculopathy and infarction in a woman with carcinomatous meningitis Journal of Neuro-Oncology. 9: 183-185. PMID 2262804 DOI: 10.1007/BF02427841  0.36
1989 Gutmann DH, Fischbeck KH, Sergott RC. Hereditary retinal vasculopathy with cerebral white matter lesions. American Journal of Medical Genetics. 34: 217-20. PMID 2817001 DOI: 10.1002/ajmg.1320340217  0.36
1989 Gutmann DH, Scherer S. Magnetic resonance imaging of ataxic hemiparesis localized to the corona radiata Stroke. 20: 1571-1573. PMID 2815193  0.36
1989 Raps EC, Gutmann DH, Brorson JR, O'Connor M, Hurtig HI. Symptomatic hydrocephalus and reversible spinal cord compression in Listeria monocytogenes meningitis. Case report. Journal of Neurosurgery. 71: 620-2. PMID 2795184 DOI: 10.3171/jns.1989.71.4.0620  0.36
1989 Gutmann DH, Fischbeck KH. Molecular biology of Duchenne and Becker's muscular dystrophy: clinical applications. Annals of Neurology. 26: 189-94. PMID 2673003 DOI: 10.1002/ana.410260202  0.36
1988 Gutmann DH, Beard BA, Collinge ML. Nonfatal disseminated mucocutaneous herpes simplex type 2 infection in a healthy woman Obstetrics and Gynecology. 72: 506-508. PMID 3405569  0.36
1985 Gutmann DH, Niederhuber JE. Major histocompatibility complex regulation of the immune response Journal of Surgical Research. 39: 172-181. PMID 3894799 DOI: 10.1016/0022-4804(85)90175-1  0.36
1985 Gutmann DH, Niederhuber JE. Separation of the immune response genes for LDH-B and MOPC-173: III. evidence that the failure of B10.basr1 to respond to LDH-b is due to an antigen-presenting cell defect Transplantation. 40: 556-562. PMID 2932822  0.36
1984 Schook LB, Gutmann DH, Marlin LE, Niederhuber JE. In–vitro–derived bone marrow macrophages Transplantation. 37: 585-590. PMID 6427997  0.36
1984 Allen PM, Gutmann DH, Sher MR, Niederhuber JE. Characterization of three new intra-I region recombinant mouse strains, B10.ASR7 (H-2as3), B10.BAR4 (H-2h6), and B10.BASR1 (H-2as4) Immunogenetics. 19: 175-178. PMID 6421725 DOI: 10.1007/BF00387862  0.36
1984 Gutmann DH, Niederhuber JE. Separation of the immune response genes for LDH-B and MOPC-173. II. Description of an immune response defect in B10.ASR7 Journal of Immunology. 132: 1955-1959. PMID 6199419  0.36
1984 Gutmann DH, Marlin LE, Niederhuber JE. Immune response defect in an intra-I-region recombinant mouse strain is localized to the level of the antigen-presenting cell Federation Proceedings. 43.  0.36
1983 Gutmann DH, Allen PM, Niederhuber JE. Separation of the immune response genes for LDH-B and MOPC-173. I. Description of an immune response defect in B10.BASR1 Journal of Immunology. 131: 2919-2923. PMID 6417235  0.36
1983 Gutmann DH. Restriction endonucleases The American Journal of Medical Technology. 49: 60. PMID 6303123  0.36
1982 Schook LB, Bingham EL, Gutmann DH, Niederhuber JE. Characterization and expression of H-2I region gene products on bone marrow-derived macrophages European Journal of Immunology. 12: 991-997. PMID 6819150  0.36
1982 Gutmann DH. The use of restriction endonucleases in the prenatal diagnosis of hemoglobinopathies The American Journal of Medical Technology. 48: 361-366. PMID 6285741  0.36
1982 Schook LB, Gutmann DH, Niederhuber JE. Characterization of bone marrow derived macrophage as Ia-bearing accessory cells Advances in Experimental Medicine and Biology. 149: 429-433. PMID 6216768  0.36
1981 Doneen BA, Gutmann DH. Lipid composition and in vitro biosynthetic rates of neutral lipids and phosphatidylcholine in anterior and posterior chambers of the goldfish swimbladder Comparative Biochemistry and Physiology -- Part a: Physiology. 69: 291-295. DOI: 10.1016/0300-9629(81)90295-4  0.36
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