Manisha Patel - Publications

Neuroscience University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Neuroscience Biology, Biochemistry

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pauletti A, Terrone G, Shekh-Ahmad T, Salamone A, Ravizza T, Rizzi M, Pastore A, Pascente R, Liang LP, Villa BR, Balosso S, Abramov AY, van Vliet EA, Del Giudice E, Aronica E, ... Patel M, et al. Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy. Brain : a Journal of Neurology. PMID 31145451 DOI: 10.1093/brain/awz130  0.64
2018 Liang LP, Pearson-Smith JN, Huang J, Day BJ, Patel M. Neuroprotective effects of a catalytic antioxidant in a rat nerve agent model. Redox Biology. 20: 275-284. PMID 30384261 DOI: 10.1016/j.redox.2018.10.010  0.64
2018 Gano LB, Liang LP, Ryan K, Michel CR, Gomez J, Vassilopoulos A, Reisdorph N, Fritz KS, Patel M. Altered Mitochondrial Acetylation Profiles in a Kainic Acid Model of Temporal Lobe Epilepsy. Free Radical Biology & Medicine. PMID 29778462 DOI: 10.1016/j.freeradbiomed.2018.05.063  0.64
2018 Heischmann S, Gano LB, Quinn K, Liang LP, Klepacki J, Christians U, Reisdorph N, Patel M. Regulation of Kynurenine Metabolism by a Ketogenic Diet. Journal of Lipid Research. PMID 29605816 DOI: 10.1194/jlr.M079251  0.64
2017 Liang LP, Pearson-Smith JN, Huang J, McElroy P, Day BJ, Patel M. Neuroprotective Effects of AEOL10150 in a Rat Organophosphate Model. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29272548 DOI: 10.1093/toxsci/kfx283  0.64
2017 McElroy PB, Liang LP, Day BJ, Patel M. Scavenging reactive oxygen species inhibits status epilepticus-induced neuroinflammation. Experimental Neurology. PMID 28822838 DOI: 10.1016/j.expneurol.2017.08.009  0.64
2017 Pauletti A, Terrone G, Shekh-Ahmad T, Salamone A, Ravizza T, Rizzi M, Pastore A, Pascente R, Liang LP, Villa BR, Balosso S, Abramov AY, van Vliet EA, Del Giudice E, Aronica E, ... ... Patel M, et al. Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy. Brain : a Journal of Neurology. PMID 28575153 DOI: 10.1093/brain/awx117  0.64
2017 Pearson-Smith JN, Liang LP, Rowley SD, Day BJ, Patel M. Oxidative Stress Contributes to Status Epilepticus Associated Mortality. Neurochemical Research. PMID 28462450 DOI: 10.1007/s11064-017-2273-1  0.64
2017 Liang LP, Huang J, Fulton R, Pearson-Smith JN, Day BJ, Patel M. Pre-clinical therapeutic development of a series of metalloporphyrins for Parkinson's disease. Toxicology and Applied Pharmacology. PMID 28400118 DOI: 10.1016/j.taap.2017.04.004  0.64
2017 McElroy PB, Sri Hari A, Day BJ, Patel M. Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A Novel Mechanism of Inhibiting Neuroinflammation in vitro. The Journal of Biological Chemistry. PMID 28202547 DOI: 10.1074/jbc.M116.723700  0.52
2016 Pearson JN, Warren E, Liang LP, Jackson Roberts L, Patel M. Scavenging of highly reactive gamma-ketoaldehydes attenuates cognitive dysfunction associated with epileptogenesis. Neurobiology of Disease. PMID 27932305 DOI: 10.1016/j.nbd.2016.11.011  0.64
2016 Heischmann S, Quinn K, Cruickshank-Quinn C, Liang LP, Reisdorph R, Reisdorph N, Patel M. Exploratory Metabolomics Profiling in the Kainic Acid Rat Model Reveals Depletion of 25-Hydroxyvitamin D3 during Epileptogenesis. Scientific Reports. 6: 31424. PMID 27526857 DOI: 10.1038/srep31424  1
2016 Patel M. Targeting Oxidative Stress in Central Nervous System Disorders. Trends in Pharmacological Sciences. PMID 27491897 DOI: 10.1016/  1
2016 Walker LE, Janigro D, Heinemann U, Riikonen R, Bernard C, Patel M. WONOEP appraisal: Molecular and cellular biomarkers for epilepsy. Epilepsia. PMID 27374986 DOI: 10.1111/epi.13460  1
2016 Liang LP, Patel M. Plasma cysteine/cystine redox couple disruption in animal models of temporal lobe epilepsy. Redox Biology. 9: 45-49. PMID 27285054 DOI: 10.1016/j.redox.2016.05.004  1
2016 Grone BP, Marchese M, Hamling KR, Kumar MG, Krasniak CS, Sicca F, Santorelli FM, Patel M, Baraban SC. Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish. Plos One. 11: e0151148. PMID 26963117 DOI: 10.1371/journal.pone.0151148  1
2015 Pearson JN, Rowley S, Liang LP, White AM, Day BJ, Patel M. Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy. Neurobiology of Disease. 82: 289-297. PMID 26184893 DOI: 10.1016/j.nbd.2015.07.005  1
2015 Bhuyan P, Patel DC, Wilcox KS, Patel M. Oxidative stress in murine Theiler's virus-induced temporal lobe epilepsy. Experimental Neurology. 271: 329-334. PMID 26079647 DOI: 10.1016/j.expneurol.2015.06.012  1
2015 Lopert P, Patel M. Mitochondrial mechanisms of redox cycling agents implicated in Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25749885 DOI: 10.1007/s00702-015-1386-4  1
2015 Patel M. Nrf2 to the rescue. Epilepsy Currents / American Epilepsy Society. 15: 39-40. PMID 25678888 DOI: 10.5698/1535-7597-15.1.39  1
2015 Rowley S, Liang LP, Fulton R, Shimizu T, Day B, Patel M. Mitochondrial respiration deficits driven by reactive oxygen species in experimental temporal lobe epilepsy. Neurobiology of Disease. 75: 151-8. PMID 25600213 DOI: 10.1016/j.nbd.2014.12.025  0.64
2014 Chandler JD, Min E, Huang J, McElroy CS, Dickerhof N, Mocatta T, Fletcher AA, Evans CM, Liang L, Patel M, Kettle AJ, Nichols DP, Day BJ. Anti-Inflammatory and Anti-Microbial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model. American Journal of Respiratory Cell and Molecular Biology. PMID 25490247 DOI: 10.1165/rcmb.2014-0208OC  1
2014 Gano LB, Patel M, Rho JM. Ketogenic diets, mitochondria, and neurological diseases. Journal of Lipid Research. 55: 2211-28. PMID 24847102 DOI: 10.1194/jlr.R048975  1
2014 Pearson JN, Schulz KM, Patel M. Specific alterations in the performance of learning and memory tasks in models of chemoconvulsant-induced status epilepticus. Epilepsy Research. 108: 1032-40. PMID 24842343 DOI: 10.1016/j.eplepsyres.2014.04.003  1
2014 Miller JA, Kirkley KA, Padmanabhan R, Liang LP, Raol YH, Patel M, Bialecki RA, Tjalkens RB. Repeated exposure to low doses of kainic acid activates nuclear factor kappa B (NF-κB) prior to seizure in transgenic NF-κB/EGFP reporter mice. Neurotoxicology. 44: 39-47. PMID 24813937 DOI: 10.1016/j.neuro.2014.04.010  0.64
2014 Ryan K, Liang LP, Rivard C, Patel M. Temporal and spatial increase of reactive nitrogen species in the kainate model of temporal lobe epilepsy. Neurobiology of Disease. 64: 8-15. PMID 24361554 DOI: 10.1016/j.nbd.2013.12.006  0.64
2013 Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE. Authors' response to letter by A. Mazarati. Epilepsia. 54: 2229-30. PMID 24304440 DOI: 10.1111/epi.12414  1
2013 Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE. Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy. Epilepsia. 54: 44-60. PMID 23909853 DOI: 10.1111/epi.12298  1
2013 Liang LP, Kavanagh TJ, Patel M. Glutathione deficiency in Gclm null mice results in complex I inhibition and dopamine depletion following paraquat administration. Toxicological Sciences : An Official Journal of the Society of Toxicology. 134: 366-73. PMID 23704229 DOI: 10.1093/toxsci/kft112  1
2012 Lopert P, Day BJ, Patel M. Thioredoxin reductase deficiency potentiates oxidative stress, mitochondrial dysfunction and cell death in dopaminergic cells. Plos One. 7: e50683. PMID 23226354 DOI: 10.1371/journal.pone.0050683  0.52
2012 Liang LP, Waldbaum S, Rowley S, Huang TT, Day BJ, Patel M. Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin. Neurobiology of Disease. 45: 1068-76. PMID 22200564 DOI: 10.1016/j.nbd.2011.12.025  1
2011 Good RL, Liang LP, Patel M, Radcliffe RA. Mouse strain- and age-dependent effects of binge methamphetamine on dopaminergic signaling. Neurotoxicology. 32: 751-9. PMID 21798282 DOI: 10.1016/j.neuro.2011.07.005  0.64
2011 Durazo SA, Kadam RS, Drechsel D, Patel M, Kompella UB. Brain mitochondrial drug delivery: influence of drug physicochemical properties. Pharmaceutical Research. 28: 2833-47. PMID 21796482 DOI: 10.1007/s11095-011-0532-4  1
2011 Cantu D, Fulton RE, Drechsel DA, Patel M. Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂. Journal of Neurochemistry. 118: 79-92. PMID 21517855 DOI: 10.1111/j.1471-4159.2011.07290.x  1
2010 Waldbaum S, Liang LP, Patel M. Persistent impairment of mitochondrial and tissue redox status during lithium-pilocarpine-induced epileptogenesis. Journal of Neurochemistry. 115: 1172-82. PMID 21219330 DOI: 10.1111/j.1471-4159.2010.07013.x  1
2010 Waldbaum S, Patel M. Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy? Journal of Bioenergetics and Biomembranes. 42: 449-55. PMID 21132357 DOI: 10.1007/s10863-010-9320-9  1
2010 Milder JB, Liang LP, Patel M. Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet. Neurobiology of Disease. 40: 238-44. PMID 20594978 DOI: 10.1016/j.nbd.2010.05.030  1
2010 Drechsel DA, Patel M. Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system. The Journal of Biological Chemistry. 285: 27850-8. PMID 20558743 DOI: 10.1074/jbc.M110.101196  1
2010 Waldbaum S, Patel M. Mitochondria, oxidative stress, and temporal lobe epilepsy. Epilepsy Research. 88: 23-45. PMID 19850449 DOI: 10.1016/j.eplepsyres.2009.09.020  1
2009 Chick WS, Drechsel DA, Hammond W, Patel M, Johnson TE. Transmission of mutant phenotypes from ES cells to adult mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 734-40. PMID 19795169 DOI: 10.1007/s00335-009-9228-z  1
2009 Drechsel DA, Patel M. Differential contribution of the mitochondrial respiratory chain complexes to reactive oxygen species production by redox cycling agents implicated in parkinsonism. Toxicological Sciences : An Official Journal of the Society of Toxicology. 112: 427-34. PMID 19767442 DOI: 10.1093/toxsci/kfp223  1
2009 Cantu D, Schaack J, Patel M. Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures. Plos One. 4: e7095. PMID 19763183 DOI: 10.1371/journal.pone.0007095  1
2009 Drechsel DA, Patel M. Chapter 21 Paraquat-induced production of reactive oxygen species in brain mitochondria. Methods in Enzymology. 456: 381-93. PMID 19348900 DOI: 10.1016/S0076-6879(08)04421-2  1
2009 Frey LC, Hellier J, Unkart C, Lepkin A, Howard A, Hasebroock K, Serkova N, Liang L, Patel M, Soltesz I, Staley K. A novel apparatus for lateral fluid percussion injury in the rat. Journal of Neuroscience Methods. 177: 267-72. PMID 19022291 DOI: 10.1016/j.jneumeth.2008.10.022  1
2008 Liang LP, Jarrett SG, Patel M. Chelation of mitochondrial iron prevents seizure-induced mitochondrial dysfunction and neuronal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11550-6. PMID 18987191 DOI: 10.1523/JNEUROSCI.3016-08.2008  0.64
2008 Jarrett SG, Milder JB, Liang LP, Patel M. The ketogenic diet increases mitochondrial glutathione levels. Journal of Neurochemistry. 106: 1044-51. PMID 18466343 DOI: 10.1111/j.1471-4159.2008.05460.x  1
2008 Drechsel DA, Patel M. Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease. Free Radical Biology & Medicine. 44: 1873-86. PMID 18342017 DOI: 10.1016/j.freeradbiomed.2008.02.008  1
2008 Jarrett SG, Liang LP, Hellier JL, Staley KJ, Patel M. Mitochondrial DNA damage and impaired base excision repair during epileptogenesis. Neurobiology of Disease. 30: 130-8. PMID 18295498 DOI: 10.1016/j.nbd.2007.12.009  1
2008 Castello PR, Drechsel DA, Day BJ, Patel M. Inhibition of mitochondrial hydrogen peroxide production by lipophilic metalloporphyrins. The Journal of Pharmacology and Experimental Therapeutics. 324: 970-6. PMID 18063723 DOI: 10.1124/jpet.107.132134  1
2008 Patel M, Liang LP, Hou H, Williams BB, Kmiec M, Swartz HM, Fessel JP, Roberts LJ. Seizure-induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension. Journal of Neurochemistry. 104: 264-70. PMID 17953661 DOI: 10.1111/j.1471-4159.2007.04974.x  1
2008 Drechsel DA, Patel M. Corrigendum to "Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease" [Free Radic. Biol. Med. 44 (2008) 1873-1886] (DOI:10.1016/j.freeradbiomed.2008.02.008) Free Radical Biology and Medicine. 45: 1045. DOI: 10.1016/j.freeradbiomed.2008.07.005  1
2007 Kulich SM, Horbinski C, Patel M, Chu CT. 6-Hydroxydopamine induces mitochondrial ERK activation. Free Radical Biology & Medicine. 43: 372-83. PMID 17602953 DOI: 10.1016/j.freeradbiomed.2007.04.028  1
2007 Liang LP, Huang J, Fulton R, Day BJ, Patel M. An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4326-33. PMID 17442816 DOI: 10.1523/JNEUROSCI.0019-07.2007  0.64
2007 Drechsel DA, Liang LP, Patel M. 1-methyl-4-phenylpyridinium-induced alterations of glutathione status in immortalized rat dopaminergic neurons. Toxicology and Applied Pharmacology. 220: 341-8. PMID 17395226 DOI: 10.1016/j.taap.2007.02.002  1
2007 Castello PR, Drechsel DA, Patel M. Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. The Journal of Biological Chemistry. 282: 14186-93. PMID 17389593 DOI: 10.1074/jbc.M700827200  1
2006 Liang LP, Patel M. Seizure-induced changes in mitochondrial redox status. Free Radical Biology & Medicine. 40: 316-22. PMID 16413413 DOI: 10.1016/j.freeradbiomed.2005.08.026  0.64
2005 Fariss MW, Chan CB, Patel M, Van Houten B, Orrenius S. Role of mitochondria in toxic oxidative stress Molecular Interventions. 5: 94-111. PMID 15821158 DOI: 10.1124/mi.5.2.7  1
2005 Patel M, Li QY, Chang LY, Crapo J, Liang LP. Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage. Journal of Neurochemistry. 92: 123-31. PMID 15606902 DOI: 10.1111/j.1471-4159.2004.02838.x  1
2004 Liang LP, Patel M. Iron-sulfur enzyme mediated mitochondrial superoxide toxicity in experimental Parkinson's disease. Journal of Neurochemistry. 90: 1076-84. PMID 15312163 DOI: 10.1111/j.1471-4159.2004.02567.x  0.64
2004 Liang LP, Patel M. Mitochondrial oxidative stress and increased seizure susceptibility in Sod2(-/+) mice. Free Radical Biology & Medicine. 36: 542-54. PMID 14980699 DOI: 10.1016/j.freeradbiomed.2003.11.029  0.64
2003 Patel MN. Metalloporphyrins improve the survival of Sod2-deficient neurons. Aging Cell. 2: 219-22. PMID 12934715  1
2003 Kachadourian R, Flaherty MM, Crumbliss AL, Patel M, Day BJ. Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin. Journal of Inorganic Biochemistry. 95: 240-8. PMID 12818794 DOI: 10.1016/S0162-0134(03)00135-1  1
2003 Bowler RP, Arcaroli J, Abraham E, Patel M, Chang LY, Crapo JD. Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L680-7. PMID 12618426 DOI: 10.1152/ajplung.00191.2002  1
2002 Patel MN. Oxidative stress, mitochondrial dysfunction, and epilepsy. Free Radical Research. 36: 1139-46. PMID 12592665 DOI: 10.1080/1071576021000016391  1
2002 Sheng H, Enghild JJ, Bowler R, Patel M, Batinić-Haberle I, Calvi CL, Day BJ, Pearlstein RD, Crapo JD, Warner DS. Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia. Free Radical Biology & Medicine. 33: 947-61. PMID 12361805 DOI: 10.1016/S0891-5849(02)00979-6  1
2002 Levin ED, Christopher NC, Lateef S, Elamir BM, Patel M, Liang LP, Crapo JD. Extracellular superoxide dismutase overexpression protects against aging-induced cognitive impairment in mice. Behavior Genetics. 32: 119-25. PMID 12036109 DOI: 10.1023/A:1015201823417  1
1998 Patel M. Inhibition of neuronal apoptosis by a metalloporphyrin superoxide dismutase mimic Journal of Neurochemistry. 71: 1068-1074. PMID 9721731  1
1998 He XP, Patel M, Whitney KD, Janumpalli S, Tenner A, McNamara JO. Glutamate receptor GluR3 antibodies and death of cortical cells. Neuron. 20: 153-63. PMID 9459451 DOI: 10.1016/S0896-6273(00)80443-2  1
1996 Patel M. Superoxide involvement in excitotoxicity: a SOD-mimetic holds promise as a novel neuroprotective agent Molecular Psychiatry. 1: 362-363. PMID 9154227  1
1996 Patel M, Day BJ, Crapo JD, Fridovich I, McNamara JO. Requirement for superoxide in excitotoxic cell death. Neuron. 16: 345-55. PMID 8789949 DOI: 10.1016/S0896-6273(00)80052-5  1
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