| Year |
Citation |
Score |
| 2022 |
Anand B, Wu Q, Nakhaei-Nejad M, Karthivashan G, Dorosh L, Amidian S, Dahal A, Li X, Stepanova M, Wille H, Giuliani F, Kar S. Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology. Bioactive Materials. 17: 506-525. PMID 36330076 DOI: 10.1016/j.bioactmat.2022.05.030 |
0.305 |
|
| 2022 |
Wu Q, Karthivashan G, Nakhaei-Nejad M, Anand BG, Giuliani F, Kar S. Native PLGA nanoparticles regulate APP metabolism and protect neurons against β-amyloid toxicity: Potential significance in Alzheimer's disease pathology. International Journal of Biological Macromolecules. 219: 1180-1196. PMID 36030976 DOI: 10.1016/j.ijbiomac.2022.08.148 |
0.334 |
|
| 2022 |
Paul PS, Cho JY, Wu Q, Karthivashan G, Grabovac E, Wille H, Kulka M, Kar S. Unconjugated PLGA nanoparticles attenuate temperature-dependent β-amyloid aggregation and protect neurons against toxicity: implications for Alzheimer's disease pathology. Journal of Nanobiotechnology. 20: 67. PMID 35120558 DOI: 10.1186/s12951-022-01269-0 |
0.305 |
|
| 2021 |
Wu Q, Cortez L, Kamali-Jamil R, Sim V, Wille H, Kar S. Implication of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology. Disease Models & Mechanisms. PMID 34524402 DOI: 10.1242/dmm.048929 |
0.368 |
|
| 2020 |
Wang Y, Wu Q, Anand BG, Karthivashan G, Phukan G, Yang J, Thinakaran G, Westaway D, Kar S. Significance of cytosolic cathepsin D in Alzheimer's disease pathology: Protective cellular effects of PLGA nanoparticles against β-amyloid-toxicity. Neuropathology and Applied Neurobiology. PMID 32716575 DOI: 10.1111/Nan.12647 |
0.448 |
|
| 2019 |
Kang SG, Mays CE, Daude N, Yang J, Kar S, Westaway D. Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus. Molecular Neurobiology. PMID 31129810 DOI: 10.1007/S12035-019-1623-1 |
0.365 |
|
| 2019 |
Baker G, Matveychuk D, MacKenzie EM, Holt A, Wang Y, Kar S. Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine. Chemico-Biological Interactions. PMID 30857888 DOI: 10.1016/J.Cbi.2019.03.003 |
0.305 |
|
| 2018 |
Ourdev D, Schmaus A, Kar S. Kainate Receptor Activation Enhances Amyloidogenic Processing of APP in Astrocytes. Molecular Neurobiology. PMID 30484111 DOI: 10.1007/S12035-018-1427-8 |
0.455 |
|
| 2018 |
Kodam A, Ourdev D, Maulik M, Hariharakrishnan J, Banerjee M, Wang Y, Kar S. A role for astrocyte-derived amyloid β peptides in the degeneration of neurons in an animal model of Temporal Lobe Epilepsy. Brain Pathology (Zurich, Switzerland). PMID 29665128 DOI: 10.1111/Bpa.12617 |
0.442 |
|
| 2018 |
Foroutanpay BV, Kumar J, Kang SG, Danaei N, Westaway D, Sim VL, Kar S. The effects of N-terminal mutations on β-amyloid peptide aggregation and toxicity. Neuroscience. PMID 29572166 DOI: 10.1016/J.Neuroscience.2018.03.014 |
0.37 |
|
| 2018 |
Chung J, Phukan G, Vergote D, Mohamed A, Maulik M, Stahn M, Andrew RJ, Thinakaran G, Posse de Chaves E, Kar S. Endosomal-lysosomal Cholesterol Sequestration by U18666A Differentially Regulates APP Metabolism in Normal and APP Overexpressing Cells. Molecular and Cellular Biology. PMID 29530923 DOI: 10.1128/Mcb.00529-17 |
0.697 |
|
| 2017 |
Maulik M, Vergote D, Phukan G, Chung J, Thinakaran G, Kar S. The Effects of Extracellular Serum Concentration on APP Processing in Npc1-Deficient APP-Overexpressing N2a Cells. Molecular Neurobiology. PMID 29052144 DOI: 10.1007/S12035-017-0799-5 |
0.69 |
|
| 2017 |
Yang H, Wang Y, Kar S. Effects of cholesterol transport inhibitor U18666A on APP metabolism in rat primary astrocytes. Glia. PMID 28722194 DOI: 10.1002/Glia.23191 |
0.459 |
|
| 2016 |
De Rossi P, Buggia-Prévot V, Clayton BL, Vasquez JB, van Sanford C, Andrew RJ, Lesnick R, Botté A, Deyts C, Salem S, Rao E, Rice RC, Parent A, Kar S, Popko B, et al. Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts. Molecular Neurodegeneration. 11: 59. PMID 27488240 DOI: 10.1186/S13024-016-0124-1 |
0.365 |
|
| 2016 |
Wang Y, MacDonald RG, Thinakaran G, Kar S. Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases. Molecular Neurobiology. PMID 26993302 DOI: 10.1007/S12035-016-9849-7 |
0.404 |
|
| 2015 |
Ourdev D, Foroutanpay BV, Wang Y, Kar S. The Effect of Aβ1-42 Oligomers on APP Processing and Aβ1-40 Generation in Cultured U-373 Astrocytes. Neuro-Degenerative Diseases. 15: 361-368. PMID 26606591 DOI: 10.1159/000438923 |
0.338 |
|
| 2015 |
Maulik M, Peake K, Chung J, Wang Y, Vance JE, Kar S. APP overexpression in absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease. Human Molecular Genetics. PMID 26433932 DOI: 10.1093/Hmg/Ddv413 |
0.712 |
|
| 2015 |
Wang Y, Buggia-Prévot V, Zavorka ME, Bleackley RC, MacDonald RG, Thinakaran G, Kar S. Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability. Molecular and Cellular Biology. 35: 2368-84. PMID 25939386 DOI: 10.1128/Mcb.01338-14 |
0.442 |
|
| 2015 |
Banerjee M, Sasse VA, Wang Y, Maulik M, Kar S. Increased levels and activity of cathepsins B and D in kainate-induced toxicity. Neuroscience. 284: 360-73. PMID 25307300 DOI: 10.1016/J.Neuroscience.2014.10.003 |
0.666 |
|
| 2014 |
Wang Y, Thinakaran G, Kar S. Overexpression of the IGF-II/M6P receptor in mouse fibroblast cell lines differentially alters expression profiles of genes involved in Alzheimer's disease-related pathology. Plos One. 9: e98057. PMID 24846272 DOI: 10.1371/Journal.Pone.0098057 |
0.46 |
|
| 2013 |
Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, et al. A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production. Cell Reports. 5: 1552-63. PMID 24373286 DOI: 10.1016/J.Celrep.2013.12.006 |
0.355 |
|
| 2013 |
Vardarajan B, Vergote D, Tissir F, Logue M, Yang J, Daude N, Ando K, Rogaeva E, Lee J, Cheng R, Brion JP, Ghani M, Shi B, Baldwin CT, Kar S, et al. Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts. Molecular Neurodegeneration. 8: 10. PMID 23414597 DOI: 10.1186/1750-1326-8-10 |
0.375 |
|
| 2013 |
Maulik M, Thinakaran G, Kar S. Alterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 protein. Plos One. 8: e54605. PMID 23382922 DOI: 10.1371/Journal.Pone.0054605 |
0.686 |
|
| 2013 |
Amritraj A, Wang Y, Revett TJ, Vergote D, Westaway D, Kar S. Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann-Pick type C disease pathogenesis. The Journal of Biological Chemistry. 288: 3136-52. PMID 23250759 DOI: 10.1074/Jbc.M112.412460 |
0.376 |
|
| 2013 |
Maulik M, Westaway D, Jhamandas JH, Kar S. Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis. Molecular Neurobiology. 47: 37-63. PMID 22983915 DOI: 10.1007/S12035-012-8337-Y |
0.692 |
|
| 2013 |
Revett TJ, Baker GB, Jhamandas J, Kar S. Glutamate system, amyloid ß peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology. Journal of Psychiatry & Neuroscience : Jpn. 38: 6-23. PMID 22894822 DOI: 10.1503/Jpn.110190 |
0.397 |
|
| 2012 |
Amritraj A, Posse de Chaves EI, Hawkes C, Macdonald RG, Kar S. Single-transmembrane domain IGF-II/M6P receptor: potential interaction with G protein and its association with cholesterol-rich membrane domains. Endocrinology. 153: 4784-98. PMID 22903618 DOI: 10.1210/En.2012-1139 |
0.326 |
|
| 2012 |
Maulik M, Ghoshal B, Kim J, Wang Y, Yang J, Westaway D, Kar S. Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin. Human Molecular Genetics. 21: 4857-75. PMID 22869680 DOI: 10.1093/Hmg/Dds322 |
0.706 |
|
| 2012 |
Gong P, Roseman J, Vetrivel KS, Bindokas VP, Zitzow LA, Kar S, Parent AT, Thinakaran G. Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease Molecular Neurodegeneration. 7: L2. DOI: 10.1186/1750-1326-7-S1-L2 |
0.388 |
|
| 2011 |
Gong P, Roseman J, Fernandez CG, Vetrivel KS, Bindokas VP, Zitzow LA, Kar S, Parent AT, Thinakaran G. Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice. Molecular Neurodegeneration. 6: 87. PMID 22204304 DOI: 10.1186/1750-1326-6-87 |
0.399 |
|
| 2011 |
Song MS, Baker GB, Todd KG, Kar S. Inhibition of β-amyloid1-42 internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons. Neuroscience. 178: 181-8. PMID 21262324 DOI: 10.1016/J.Neuroscience.2010.12.055 |
0.436 |
|
| 2010 |
Amritraj A, Rauw G, Baker GB, Kar S. Leu27 insulin-like growth factor-II, an insulin-like growth factor-II analog, attenuates depolarization-evoked GABA release from adult rat hippocampal and cortical slices. Neuroscience. 170: 722-30. PMID 20659530 DOI: 10.1016/J.Neuroscience.2010.07.026 |
0.327 |
|
| 2010 |
Kodam A, Maulik M, Peake K, Amritraj A, Vetrivel KS, Thinakaran G, Vance JE, Kar S. Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains. Glia. 58: 1267-81. PMID 20607864 DOI: 10.1002/Glia.21001 |
0.696 |
|
| 2010 |
Kabogo D, Rauw G, Amritraj A, Baker G, Kar S. β-Amyloid-related peptides potentiate K+-evoked glutamate release from adult rat hippocampal slices Neurobiology of Aging. 31: 1164-1172. PMID 18819729 DOI: 10.1016/J.Neurobiolaging.2008.08.009 |
0.437 |
|
| 2009 |
Amritraj A, Peake K, Kodam A, Salio C, Merighi A, Vance JE, Kar S. Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice. The American Journal of Pathology. 175: 2540-56. PMID 19893049 DOI: 10.2353/Ajpath.2009.081096 |
0.409 |
|
| 2008 |
Song MS, Rauw G, Baker GB, Kar S. Memantine protects rat cortical cultured neurons against β-amyloid-induced toxicity by attenuating tau phosphorylation European Journal of Neuroscience. 28: 1989-2002. PMID 19046381 DOI: 10.1111/J.1460-9568.2008.06498.X |
0.448 |
|
| 2008 |
Vetrivel KS, Kodam A, Gong P, Chen Y, Parent AT, Kar S, Thinakaran G. Localization and regional distribution of p23/TMP21 in the brain. Neurobiology of Disease. 32: 37-49. PMID 18652896 DOI: 10.1016/J.Nbd.2008.06.012 |
0.394 |
|
| 2008 |
Wei Z, Song MS, MacTavish D, Jhamandas JH, Kar S. Role of calpain and caspase in β-amyloid-induced cell death in rat primary septal cultured neurons Neuropharmacology. 54: 721-733. PMID 18222494 DOI: 10.1016/J.Neuropharm.2007.12.006 |
0.453 |
|
| 2008 |
Kodam A, Vetrivel KS, Thinakaran G, Kar S. Cellular distribution of γ-secretase subunit nicastrin in the developing and adult rat brains Neurobiology of Aging. 29: 724-738. PMID 17222950 DOI: 10.1016/J.Neurobiolaging.2006.12.005 |
0.362 |
|
| 2007 |
Hawkes C, Amritraj A, MacDonald RG, Jhamandas JH, Kar S. Heterotrimeric G proteins and the single-transmembrane domain IGF-II/M6P receptor: Functional interaction and relevance to cell signaling Molecular Neurobiology. 35: 329-345. PMID 17917122 DOI: 10.1007/S12035-007-0021-2 |
0.303 |
|
| 2007 |
Saavedra L, Mohamed A, Ma V, Kar S, De Chaves EP. Internalization of β-amyloid peptide by primary neurons in the absence of apolipoprotein E Journal of Biological Chemistry. 282: 35722-35732. PMID 17911110 DOI: 10.1074/Jbc.M701823200 |
0.416 |
|
| 2007 |
Amritraj A, Hawkes C, Phinney AL, Mount HT, Scott CD, Westaway D, Kar S. Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains. Neurobiology of Aging. 30: 54-70. PMID 17561313 DOI: 10.1016/J.Neurobiolaging.2007.05.004 |
0.455 |
|
| 2007 |
Dikkes P, Hawkes C, Kar S, Lopez MF. Effect of kainic acid treatment on insulin-like growth factor-2 receptors in the IGF2-deficient adult mouse brain Brain Research. 1131: 77-87. PMID 17184742 DOI: 10.1016/J.Brainres.2006.11.022 |
0.355 |
|
| 2006 |
Hawkes C, Kabogo D, Amritraj A, Kar S. Up-regulation of cation-independent mannose 6-phosphate receptor and endosomal-lysosomal markers in surviving neurons after 192-IgG-saporin administrations into the adult rat brain. The American Journal of Pathology. 169: 1140-54. PMID 17003474 DOI: 10.2353/Ajpath.2006.051208 |
0.374 |
|
| 2006 |
Boksa P, Zhang Y, Amritraj A, Kar S. Birth insults involving hypoxia produce long-term increases in hippocampal [125I]insulin-like growth factor-I and -II receptor binding in the rat Neuroscience. 139: 451-462. PMID 16448776 DOI: 10.1016/J.Neuroscience.2005.12.017 |
0.313 |
|
| 2006 |
Hawkes C, Jhamandas JH, Harris KH, Fu W, MacDonald RG, Kar S. Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 585-96. PMID 16407557 DOI: 10.1523/Jneurosci.2730-05.2006 |
0.363 |
|
| 2006 |
Kar S, Poirier J, Guevara J, Dea D, Hawkes C, Robitaille Y, Quirion R. Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology. Neurobiology of Aging. 27: 199-210. PMID 16399207 DOI: 10.1016/J.Neurobiolaging.2005.03.005 |
0.446 |
|
| 2006 |
Ding X, MacTavish D, Kar S, Jhamandas JH. Galanin attenuates beta-amyloid (Abeta) toxicity in rat cholinergic basal forebrain neurons. Neurobiology of Disease. 21: 413-20. PMID 16246567 DOI: 10.1016/J.Nbd.2005.08.016 |
0.463 |
|
| 2006 |
Hawkes C, Wei Z, Kabogo D, Kar S. P2-048: Up-regulation of IGF-II/M6P receptor and other endosomal-lysosomal markers in cells surviving toxicity Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.885 |
0.305 |
|
| 2005 |
Hawkes C, Jhamandas JH, Kar S. Selective loss of basal forebrain cholinergic neurons by 192 IgG-saporin is associated with decreased phosphorylation of Ser9 glycogen synthase kinase-3β Journal of Neurochemistry. 95: 263-272. PMID 16181430 DOI: 10.1111/J.1471-4159.2005.03363.X |
0.366 |
|
| 2005 |
Jhamandas JH, Wie MB, Harris K, MacTavish D, Kar S. Fucoidan inhibits cellular and neurotoxic effects of β‐amyloid (Aβ) in rat cholinergic basal forebrain neurons European Journal of Neuroscience. 21: 2649-2659. PMID 15926913 DOI: 10.1111/J.1460-9568.2005.04111.X |
0.353 |
|
| 2004 |
Kar S, Slowikowski SP, Westaway D, Mount HT. Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease. Journal of Psychiatry & Neuroscience : Jpn. 29: 427-41. PMID 15644984 |
0.346 |
|
| 2004 |
Hawkes C, Kar S. The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system. Brain Research Reviews. 44: 117-140. PMID 15003389 DOI: 10.1016/J.Brainresrev.2003.11.002 |
0.35 |
|
| 2004 |
Kar S, Quirion R. Amyloid beta peptides and central cholinergic neurons: functional interrelationship and relevance to Alzheimer's disease pathology. Progress in Brain Research. 145: 261-74. PMID 14650921 DOI: 10.1016/S0079-6123(03)45018-8 |
0.427 |
|
| 2003 |
Hawkes C, Kar S. Insulin-like growth factor-II/mannose-6-phosphate receptor: widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype. The Journal of Comparative Neurology. 458: 113-27. PMID 12596253 DOI: 10.1002/Cne.10578 |
0.386 |
|
| 2002 |
Zheng W-, Bastianetto S, Mennicken F, Ma W, Kar S. Amyloid β peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures Neuroscience. 115: 201-211. PMID 12401334 DOI: 10.1016/S0306-4522(02)00404-9 |
0.428 |
|
| 2002 |
Zheng WH, Kar S, Quirion R. Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons. Molecular Pharmacology. 62: 225-33. PMID 12130673 DOI: 10.1124/Mol.62.2.225 |
0.339 |
|
| 2002 |
Kalynchuk LE, Meaney MJ, Kar S. Amygdala kindling decreases insulin-like growth factor-I receptor binding sites in the rat hippocampus. Brain Research. 935: 118-23. PMID 12062481 DOI: 10.1016/S0006-8993(02)02459-9 |
0.332 |
|
| 2002 |
Vaucher E, Fluit P, Chishti MA, Westaway D, Mount HTJ, Kar S. Object recognition memory and cholinergic parameters in mice expressing human presenilin 1 transgenes Experimental Neurology. 175: 398-406. PMID 12061869 DOI: 10.1006/Exnr.2002.7915 |
0.4 |
|
| 2002 |
Zheng WH, Kar S, Quirion R. FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling. Journal of Neurochemistry. 80: 1049-61. PMID 11953455 DOI: 10.1046/J.0022-3042.2002.00783.X |
0.32 |
|
| 2002 |
Hawkes C, Kar S. Insulin-like growth factor-II/Mannose-6-phosphate receptor in the spinal cord and dorsal root ganglia of the adult rat European Journal of Neuroscience. 15: 33-39. PMID 11860504 DOI: 10.1046/J.0953-816X.2001.01864.X |
0.345 |
|
| 2002 |
Kar S. Role of amyloid β peptides in the regulation of central cholinergic function and its relevance to Alzheimer's disease pathology Drug Development Research. 56: 248-263. DOI: 10.1002/ddr.10080 |
0.362 |
|
| 2001 |
Vaucher E, Aumont N, Pearson D, Rowe W, Poirier J, Kar S. Amyloid beta peptide levels and its effects on hippocampal acetylcholine release in aged, cognitively-impaired and -unimpaired rats. Journal of Chemical Neuroanatomy. 21: 323-9. PMID 11429273 DOI: 10.1016/S0891-0618(01)00120-X |
0.426 |
|
| 2001 |
Ma W, Zheng WH, Belanger S, Kar S, Quirion R. Effects of amyloid peptides on cell viability and expression of neuropeptides in cultured rat dorsal root ganglion neurons: a role for free radicals and protein kinase C. The European Journal of Neuroscience. 13: 1125-35. PMID 11285010 DOI: 10.1046/J.1460-9568.2001.01475.X |
0.387 |
|
| 2000 |
Zheng WH, Kar S, Doré S, Quirion R. Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. Journal of Neural Transmission. Supplementum. 261-72. PMID 11205145 DOI: 10.1007/978-3-7091-6301-6_17 |
0.353 |
|
| 2000 |
Jafferali S, Dumont Y, Sotty F, Robitaille Y, Quirion R, Kar S. Insulin-like growth factor-I and its receptor in the frontal cortex, hippocampus, and cerebellum of normal human and alzheimer disease brains. Synapse (New York, N.Y.). 38: 450-9. PMID 11044892 DOI: 10.1002/1098-2396(20001215)38:4<450::Aid-Syn10>3.0.Co;2-J |
0.438 |
|
| 2000 |
Ma W, Zheng WH, Kar S, Quirion R. Morphine treatment induced calcitonin gene-related peptide and substance P increases in cultured dorsal root ganglion neurons. Neuroscience. 99: 529-39. PMID 11029544 DOI: 10.1016/S0306-4522(00)00226-8 |
0.366 |
|
| 2000 |
Marinelli PW, Gianoulakis C, Kar S. Effects of voluntary ethanol drinking on [125I]insulin-like growth factor-I, [125I]insulin-like growth factor-II and [125I]insulin receptor binding in the mouse hippocampus and cerebellum. Neuroscience. 98: 687-695. PMID 10891612 DOI: 10.1016/S0306-4522(00)00174-3 |
0.311 |
|
| 2000 |
Doré S, Kar S, Zheng WH, Quirion R. Rediscovering good old friend IGF-I in the new millenium: possible usefulness in Alzheimer's disease and stroke. Pharmaceutica Acta Helvetiae. 74: 273-80. PMID 10812969 DOI: 10.1016/S0031-6865(99)00037-0 |
0.392 |
|
| 2000 |
Zheng WH, Kar S, Quirion R. Stimulation of protein kinase C modulates insulin-like growth factor-1-induced akt activation in PC12 cells. The Journal of Biological Chemistry. 275: 13377-85. PMID 10788447 DOI: 10.1074/Jbc.275.18.13377 |
0.302 |
|
| 1999 |
Doré S, Bastianetto S, Kar S, Quirion R. Protective and rescuing abilities of IGF-I and some putative free radical scavengers against beta-amyloid-inducing toxicity in neurons. Annals of the New York Academy of Sciences. 890: 356-64. PMID 10668442 DOI: 10.1111/J.1749-6632.1999.Tb08015.X |
0.358 |
|
| 1999 |
Doré S, Kar S, Chabot JG, Quirion R. Impact of neonatal kainate treatment on hippocampal insulin-like growth factor receptors. Neuroscience. 91: 1035-43. PMID 10391481 DOI: 10.1016/S0306-4522(98)00646-0 |
0.335 |
|
| 1998 |
Kar S, Issa AM, Seto D, Auld DS, Collier B, Quirion R. Amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices. Journal of Neurochemistry. 70: 2179-87. PMID 9572306 DOI: 10.1046/J.1471-4159.1998.70052179.X |
0.377 |
|
| 1998 |
Auld DS, Kar S, Quirion R. Beta-amyloid peptides as direct cholinergic neuromodulators: a missing link? Trends in Neurosciences. 21: 43-9. PMID 9464686 DOI: 10.1016/S0166-2236(97)01144-2 |
0.423 |
|
| 1998 |
Doré S, Kar S, Auld D, Chabot J, Quirion R. Autoradiographic Localization of Growth Factor Receptors in Neuronal Tissues Current Protocols in Pharmacology. 3. DOI: 10.1002/0471141755.Ph0802S03 |
0.323 |
|
| 1997 |
Kar S, Seto D, Doré S, Hanisch U, Quirion R. Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation. Proceedings of the National Academy of Sciences of the United States of America. 94: 14054-9. PMID 9391151 DOI: 10.1073/Pnas.94.25.14054 |
0.334 |
|
| 1997 |
Kar S, Seto D, Doré S, Chabot JG, Quirion R. Systemic administration of kainic acid induces selective time dependent decrease in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in adult rat hippocampal formation. Neuroscience. 80: 1041-55. PMID 9284059 DOI: 10.1016/S0306-4522(97)00185-1 |
0.353 |
|
| 1997 |
Doré S, Kar S, Rowe W, Quirion R. Distribution and levels of [125I]IGF-I, [125I]IGF-II and [125I]insulin receptor binding sites in the hippocampus of aged memory-unimpaired and -impaired rats. Neuroscience. 80: 1033-40. PMID 9284058 DOI: 10.1016/S0306-4522(97)00154-1 |
0.341 |
|
| 1997 |
Doré S, Kar S, Quirion R. Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases. Trends in Neurosciences. 20: 326-31. PMID 9246719 DOI: 10.1016/S0166-2236(96)01036-3 |
0.38 |
|
| 1997 |
Doré S, Kar S, Quirion R. Presence and differential internalization of two distinct insulin-like growth factor receptors in rat hippocampal neurons. Neuroscience. 78: 373-83. PMID 9145794 DOI: 10.1016/S0306-4522(96)00594-5 |
0.314 |
|
| 1997 |
Doré S, Kar S, Quirion R. Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity. Proceedings of the National Academy of Sciences of the United States of America. 94: 4772-7. PMID 9114067 DOI: 10.1073/Pnas.94.9.4772 |
0.465 |
|
| 1996 |
Doré S, Krieger C, Kar S, Quirion R. Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients. Brain Research. Molecular Brain Research. 41: 128-33. PMID 8883943 DOI: 10.1016/0169-328X(96)00081-2 |
0.33 |
|
| 1996 |
Ménard DP, van Rossum D, Kar S, Quirion R. Alteration of calcitonin gene related peptide and its receptor binding sites during the development of tolerance to mu and delta opioids. Canadian Journal of Physiology and Pharmacology. 73: 1089-95. PMID 8846407 DOI: 10.1139/Y95-156 |
0.309 |
|
| 1996 |
Lopes P, Kar S, Chrétien L, Regoli D, Quirion R, Couture R. Quantitative autoradiographic localization of [125I-Tyr8]bradykinin receptor binding sites in the rat spinal cord: effects of neonatal capsaicin, noradrenergic deafferentation, dorsal rhizotomy and peripheral axotomy. Neuroscience. 68: 867-81. PMID 8577380 DOI: 10.1016/0306-4522(95)00161-B |
0.306 |
|
| 1996 |
Menard D, van Rossum D, Kar S, St Pierre S, Sutak M, Jhamandas K, Quirion R. A calcitonin gene-related peptide receptor antagonist prevents the development of tolerance to spinal morphine analgesia The Journal of Neuroscience. 16: 2342-2351. DOI: 10.1523/Jneurosci.16-07-02342.1996 |
0.306 |
|
| 1996 |
Kar S, Seto D, Gaudreau P, Quirion R. Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices The Journal of Neuroscience. 16: 1034-1040. DOI: 10.1523/Jneurosci.16-03-01034.1996 |
0.353 |
|
| 1995 |
Kar S, Quirion R. Neuropeptide receptors in developing and adult rat spinal cord: An in vitro quantitative autoradiography study of calcitonin gene-related peptide, neurokinins, μ-opioid, galanin, somatostatin, neurotensin and vasoactive intestinal polypeptide receptors Journal of Comparative Neurology. 354: 253-281. PMID 7782502 DOI: 10.1002/Cne.903540208 |
0.357 |
|
| 1994 |
Kar S, Rees RG, Quirion R. Altered calcitonin gene-related peptide, substance P and enkephalin immunoreactivities and receptor binding sites in the dorsal spinal cord of the polyarthritic rat. The European Journal of Neuroscience. 6: 345-54. PMID 7517279 DOI: 10.1111/J.1460-9568.1994.Tb00277.X |
0.349 |
|
| 1993 |
Kar S, Baccichet A, Quirion R, Poirier J. Entorhinal cortex lesion induces differential responses in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in the rat hippocampal formation. Neuroscience. 55: 69-80. PMID 8350993 DOI: 10.1016/0306-4522(93)90455-O |
0.322 |
|
| 1993 |
Kar S, Chabot JG, Quirion R. Quantitative autoradiographic localization of [125I]insulin-like growth factor I, [125I]insulin-like growth factor II, and [125I]insulin receptor binding sites in developing and adult rat brain. The Journal of Comparative Neurology. 333: 375-97. PMID 8349849 DOI: 10.1002/Cne.903330306 |
0.348 |
|
| 1992 |
Yashpal K, Kar S, Dennis T, Quirion R. Quantitative autoradiographic distribution of calcitonin gene-related peptide (hCGRP alpha) binding sites in the rat and monkey spinal cord. The Journal of Comparative Neurology. 322: 224-32. PMID 1326007 DOI: 10.1002/Cne.903220208 |
0.301 |
|
| 1992 |
Kar S, Quirion R. Quantitative autoradiographic localization of [125I] neuropeptide Y receptor binding sites in rat spinal cord and the effects of neonatal capsaicin, dorsal rhizotomy and peripheral axotomy Brain Research. 574: 333-337. PMID 1322224 DOI: 10.1016/0006-8993(92)90836-X |
0.315 |
|
| 1991 |
Kar S, Gibson SJ, Rees RG, Jura WGZO, Brewerton DA, Polak JM. Increased calcitonin gene-related peptide (CGRP), substance P, and enkephalin immunoreactivities in dorsal spinal cord and loss of CGRP-immunoreactive motoneurons in arthritic rats depend on intact peripheral nerve supply. Journal of Molecular Neuroscience. 3: 7-18. PMID 1715733 DOI: 10.1007/Bf02896844 |
0.31 |
|
| 1990 |
Karanth SS, Springall DR, Kar S, Gibson SJ, Royston JP, Banerjee DK, Polak JM. Time-related decrease of substance P and CGRP in central and peripheral projections of sensory neurones in Mycobacterium leprae infected nude mice: a model for lepromatous leprosy in man. The Journal of Pathology. 160: 335-45. PMID 1694240 DOI: 10.1002/Path.1711600411 |
0.31 |
|
| 1989 |
Kar S, Bretherton-Watt D, Gibson SJ, Steel JH, Gentleman SM, Roberts GW, Valentino K, Tatemoto K, Ghatei MA, Bloom SR, Polak JM. Novel peptide pancreastatin: its occurrence and codistribution with chromogranin A in the central nervous system of the pig. The Journal of Comparative Neurology. 288: 627-639. PMID 2808753 DOI: 10.1002/Cne.902880409 |
0.346 |
|
| 1989 |
Kar S, Gibson SJ, Scaravilli F, Jacobs JM, Aber VR, Polak JM. Reduced numbers of calcitonin gene-related peptide-(CGRP-) and tachykinin-immunoreactive sensory neurones associated with greater enkephalin immunoreactivity in the dorsal horn of a mutant rat with hereditary sensory neuropathy. Cell and Tissue Research. 255: 451-66. PMID 2784359 DOI: 10.1007/Bf00224131 |
0.362 |
|
| 1989 |
Kar S, Merighi A, Gibson SJ, Polak JM. Synaptophysin immunoreactivity is expressed in all sensory neurones of the dorsal root and trigeminal ganglia in rat and pig Regulatory Peptides. 26: 76. DOI: 10.1016/0167-0115(89)90147-X |
0.319 |
|
| 1989 |
Kar S, Gibson SJ, Jura WGZO, Rees RG, Brewerton DA, Polak JM. Marked changes of calcitonin gene-related peptide (CGRP), substance P and enkephalin occur in the spinal cord and dorsal root ganglia of rats with adjuvant arthritis Regulatory Peptides. 26: 76. DOI: 10.1016/0167-0115(89)90146-8 |
0.307 |
|
| 1988 |
Gibson SJ, Polak JM, Giaid A, Hamid QA, Kar S, Jones PM, Denny P, Legon S, Amara SG, Craig RK. Calcitonin gene-related peptide messenger RNA is expressed in sensory neurones of the dorsal root ganglia and also in spinal motoneurones in man and rat. Neuroscience Letters. 91: 283-8. PMID 3263591 DOI: 10.1016/0304-3940(88)90694-5 |
0.36 |
|
| 1988 |
Kar S, Gibson SJ, Scaravilli F, Jacobs J, Polak JM. Loss of CGRP- and tachykinin-containing primary sensory neurones is accompanied by an increase of enkephalin immunoreactivity in the dorsal horn of the mutilated foot rat Regulatory Peptides. 22: 412. DOI: 10.1016/0167-0115(88)90167-X |
0.33 |
|
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