Year |
Citation |
Score |
2019 |
Kang SG, Mays CE, Daude N, Yang J, Kar S, Westaway D. Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus. Molecular Neurobiology. PMID 31129810 DOI: 10.1007/s12035-019-1623-1 |
0.44 |
|
2019 |
Baker G, Matveychuk D, MacKenzie EM, Holt A, Wang Y, Kar S. Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine. Chemico-Biological Interactions. PMID 30857888 DOI: 10.1016/j.cbi.2019.03.003 |
0.44 |
|
2018 |
Kodam A, Ourdev D, Maulik M, Hariharakrishnan J, Banerjee M, Wang Y, Kar S. A role for astrocyte-derived amyloid β peptides in the degeneration of neurons in an animal model of Temporal Lobe Epilepsy. Brain Pathology (Zurich, Switzerland). PMID 29665128 DOI: 10.1111/bpa.12617 |
0.56 |
|
2018 |
Chung J, Phukan G, Vergote D, Mohamed A, Maulik M, Stahn M, Andrew RJ, Thinakaran G, Posse de Chaves E, Kar S. Endosomal-lysosomal Cholesterol Sequestration by U18666A Differentially Regulates APP Metabolism in Normal and APP Overexpressing Cells. Molecular and Cellular Biology. PMID 29530923 DOI: 10.1128/MCB.00529-17 |
0.56 |
|
2017 |
Maulik M, Vergote D, Phukan G, Chung J, Thinakaran G, Kar S. The Effects of Extracellular Serum Concentration on APP Processing in Npc1-Deficient APP-Overexpressing N2a Cells. Molecular Neurobiology. PMID 29052144 DOI: 10.1007/s12035-017-0799-5 |
0.56 |
|
2017 |
Yang H, Wang Y, Kar S. Effects of cholesterol transport inhibitor U18666A on APP metabolism in rat primary astrocytes. Glia. PMID 28722194 DOI: 10.1002/glia.23191 |
0.44 |
|
2016 |
De Rossi P, Buggia-Prévot V, Clayton BL, Vasquez JB, van Sanford C, Andrew RJ, Lesnick R, Botté A, Deyts C, Salem S, Rao E, Rice RC, Parent A, Kar S, Popko B, et al. Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts. Molecular Neurodegeneration. 11: 59. PMID 27488240 DOI: 10.1186/s13024-016-0124-1 |
0.56 |
|
2016 |
Wang Y, MacDonald RG, Thinakaran G, Kar S. Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases. Molecular Neurobiology. PMID 26993302 DOI: 10.1007/s12035-016-9849-7 |
0.56 |
|
2015 |
Ourdev D, Foroutanpay BV, Wang Y, Kar S. The Effect of Aβ1-42 Oligomers on APP Processing and Aβ1-40 Generation in Cultured U-373 Astrocytes. Neuro-Degenerative Diseases. 15: 361-368. PMID 26606591 DOI: 10.1159/000438923 |
0.44 |
|
2015 |
Maulik M, Peake K, Chung J, Wang Y, Vance JE, Kar S. APP overexpression in absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease. Human Molecular Genetics. PMID 26433932 DOI: 10.1093/hmg/ddv413 |
0.56 |
|
2015 |
Wang Y, Buggia-Prévot V, Zavorka ME, Bleackley RC, MacDonald RG, Thinakaran G, Kar S. Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability. Molecular and Cellular Biology. 35: 2368-84. PMID 25939386 DOI: 10.1128/MCB.01338-14 |
0.56 |
|
2015 |
Banerjee M, Sasse VA, Wang Y, Maulik M, Kar S. Increased levels and activity of cathepsins B and D in kainate-induced toxicity. Neuroscience. 284: 360-73. PMID 25307300 DOI: 10.1016/j.neuroscience.2014.10.003 |
0.56 |
|
2014 |
Wang Y, Thinakaran G, Kar S. Overexpression of the IGF-II/M6P receptor in mouse fibroblast cell lines differentially alters expression profiles of genes involved in Alzheimer's disease-related pathology. Plos One. 9: e98057. PMID 24846272 DOI: 10.1371/journal.pone.0098057 |
0.56 |
|
2013 |
Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, et al. A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production. Cell Reports. 5: 1552-63. PMID 24373286 DOI: 10.1016/j.celrep.2013.12.006 |
0.56 |
|
2013 |
Vardarajan B, Vergote D, Tissir F, Logue M, Yang J, Daude N, Ando K, Rogaeva E, Lee J, Cheng R, Brion JP, Ghani M, Shi B, Baldwin CT, Kar S, et al. Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts. Molecular Neurodegeneration. 8: 10. PMID 23414597 DOI: 10.1186/1750-1326-8-10 |
0.56 |
|
2013 |
Maulik M, Thinakaran G, Kar S. Alterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 protein. Plos One. 8: e54605. PMID 23382922 DOI: 10.1371/journal.pone.0054605 |
0.56 |
|
2013 |
Amritraj A, Wang Y, Revett TJ, Vergote D, Westaway D, Kar S. Role of cathepsin D in U18666A-induced neuronal cell death: potential implication in Niemann-Pick type C disease pathogenesis. The Journal of Biological Chemistry. 288: 3136-52. PMID 23250759 DOI: 10.1074/jbc.M112.412460 |
0.44 |
|
2013 |
Maulik M, Westaway D, Jhamandas JH, Kar S. Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis. Molecular Neurobiology. 47: 37-63. PMID 22983915 DOI: 10.1007/s12035-012-8337-y |
0.56 |
|
2013 |
Revett TJ, Baker GB, Jhamandas J, Kar S. Glutamate system, amyloid ß peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology. Journal of Psychiatry & Neuroscience : Jpn. 38: 6-23. PMID 22894822 DOI: 10.1503/jpn.110190 |
0.56 |
|
2012 |
Amritraj A, Posse de Chaves EI, Hawkes C, Macdonald RG, Kar S. Single-transmembrane domain IGF-II/M6P receptor: potential interaction with G protein and its association with cholesterol-rich membrane domains. Endocrinology. 153: 4784-98. PMID 22903618 DOI: 10.1210/en.2012-1139 |
0.56 |
|
2012 |
Maulik M, Ghoshal B, Kim J, Wang Y, Yang J, Westaway D, Kar S. Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin. Human Molecular Genetics. 21: 4857-75. PMID 22869680 DOI: 10.1093/hmg/dds322 |
0.56 |
|
2011 |
Gong P, Roseman J, Fernandez CG, Vetrivel KS, Bindokas VP, Zitzow LA, Kar S, Parent AT, Thinakaran G. Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice. Molecular Neurodegeneration. 6: 87. PMID 22204304 DOI: 10.1186/1750-1326-6-87 |
0.56 |
|
2010 |
Kodam A, Maulik M, Peake K, Amritraj A, Vetrivel KS, Thinakaran G, Vance JE, Kar S. Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains. Glia. 58: 1267-81. PMID 20607864 DOI: 10.1002/glia.21001 |
0.56 |
|
2009 |
Amritraj A, Peake K, Kodam A, Salio C, Merighi A, Vance JE, Kar S. Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice. The American Journal of Pathology. 175: 2540-56. PMID 19893049 DOI: 10.2353/ajpath.2009.081096 |
0.56 |
|
2008 |
Vetrivel KS, Kodam A, Gong P, Chen Y, Parent AT, Kar S, Thinakaran G. Localization and regional distribution of p23/TMP21 in the brain. Neurobiology of Disease. 32: 37-49. PMID 18652896 DOI: 10.1016/j.nbd.2008.06.012 |
0.56 |
|
2007 |
Hawkes C, Amritraj A, MacDonald RG, Jhamandas JH, Kar S. Heterotrimeric G proteins and the single-transmembrane domain IGF-II/M6P receptor: Functional interaction and relevance to cell signaling Molecular Neurobiology. 35: 329-345. PMID 17917122 DOI: 10.1007/s12035-007-0021-2 |
0.56 |
|
2007 |
Saavedra L, Mohamed A, Ma V, Kar S, De Chaves EP. Internalization of β-amyloid peptide by primary neurons in the absence of apolipoprotein E Journal of Biological Chemistry. 282: 35722-35732. PMID 17911110 DOI: 10.1074/jbc.M701823200 |
0.56 |
|
2006 |
Hawkes C, Jhamandas JH, Harris KH, Fu W, MacDonald RG, Kar S. Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 585-96. PMID 16407557 DOI: 10.1523/JNEUROSCI.2730-05.2006 |
0.56 |
|
2006 |
Ding X, MacTavish D, Kar S, Jhamandas JH. Galanin attenuates beta-amyloid (Abeta) toxicity in rat cholinergic basal forebrain neurons. Neurobiology of Disease. 21: 413-20. PMID 16246567 DOI: 10.1016/j.nbd.2005.08.016 |
0.44 |
|
2004 |
Kar S, Slowikowski SP, Westaway D, Mount HT. Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease. Journal of Psychiatry & Neuroscience : Jpn. 29: 427-41. PMID 15644984 |
0.44 |
|
2002 |
Kalynchuk LE, Meaney MJ, Kar S. Amygdala kindling decreases insulin-like growth factor-I receptor binding sites in the rat hippocampus. Brain Research. 935: 118-23. PMID 12062481 DOI: 10.1016/S0006-8993(02)02459-9 |
0.56 |
|
2002 |
Kar S. Role of amyloid β peptides in the regulation of central cholinergic function and its relevance to Alzheimer's disease pathology Drug Development Research. 56: 248-263. DOI: 10.1002/ddr.10080 |
0.56 |
|
1994 |
Kar S, Quirion R. Galanin receptor binding sites in adult rat spinal cord respond differentially to neonatal capsaicin, dorsal rhizotomy and peripheral axotomy European Journal of Neuroscience. 6: 1917-1921. PMID 7704302 DOI: 10.1111/j.1460-9568.1994.tb00583.x |
0.56 |
|
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