William J. Bowers, Ph.D. - Publications

Affiliations: 
Neurology, Center for Neural Development and Disease University of Rochester Medical Center, Rochester, NY, United States 
Area:
CNS Gene Therapy, Immunotherapy, Neuroinflammation, Alzheimer's Disease

114/163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Southwell AL, Franciosi S, Villanueva EB, Xie Y, Winter LA, Veeraraghavan J, Jonason A, Felczak B, Zhang W, Kovalik V, Waltl S, Hall G, Pouladi MA, Smith ES, Bowers WJ, et al. Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease. Neurobiology of Disease. 76: 46-56. PMID 25662335 DOI: 10.1016/J.Nbd.2015.01.002  0.361
2015 Evans EE, Jonason AS, Bussler H, Torno S, Veeraraghavan J, Reilly C, Doherty MA, Seils J, Winter LA, Mallow C, Kirk R, Howell A, Giralico S, Scrivens M, Klimatcheva K, ... ... Bowers WJ, et al. Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies. Cancer Immunology Research. 3: 689-701. PMID 25614511 DOI: 10.1158/2326-6066.Cir-14-0171  0.312
2014 Smith ES, Jonason A, Reilly C, Veeraraghavan J, Fisher T, Doherty M, Klimatcheva E, Mallow C, Cornelius C, Leonard JE, Marchi N, Janigro D, Argaw AT, Pham T, Seils J, ... ... Bowers WJ, et al. SEMA4D compromises blood-brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease. Neurobiology of Disease. 73: 254-268. PMID 25461192 DOI: 10.1016/J.Nbd.2014.10.008  0.355
2013 Montgomery SL, Narrow WC, Mastrangelo MA, Olschowka JA, O'Banion MK, Bowers WJ. Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies. The American Journal of Pathology. 182: 2285-97. PMID 23567638 DOI: 10.1016/J.Ajpath.2013.02.030  0.655
2012 Montgomery SL, Bowers WJ. Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 42-59. PMID 21728035 DOI: 10.1007/S11481-011-9287-2  0.623
2011 Hadaczek P, Beyer J, Kells A, Narrow W, Bowers W, Federoff HJ, Forsayeth J, Bankiewicz KS. Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system. Plos One. 6: e27728. PMID 22132130 DOI: 10.1371/Journal.Pone.0027728  0.532
2011 Schnell L, Hunanyan AS, Bowers WJ, Horner PJ, Federoff HJ, Gullo M, Schwab ME, Mendell LM, Arvanian VL. Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. The European Journal of Neuroscience. 34: 1256-67. PMID 21995852 DOI: 10.1111/J.1460-9568.2011.07862.X  0.485
2011 Hunter JM, Bowers WJ, Maarouf CL, Mastrangelo MA, Daugs ID, Kokjohn TA, Kalback WM, Luehrs DC, Valla J, Beach TG, Roher AE. Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 361-76. PMID 21860086 DOI: 10.3233/Jad-2011-110608  0.373
2011 Montgomery SL, Mastrangelo MA, Habib D, Narrow WC, Knowlden SA, Wright TW, Bowers WJ. Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain. The American Journal of Pathology. 179: 2053-70. PMID 21835156 DOI: 10.1016/J.Ajpath.2011.07.001  0.658
2011 Domm W, Brooks L, Chung HL, Feng C, Bowers WJ, Watson G, McGrath JL, Dewhurst S. Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier. Vaccine. 29: 7080-9. PMID 21801777 DOI: 10.1016/J.Vaccine.2011.07.008  0.368
2011 de Silva S, Bowers WJ. Targeting the central nervous system with herpes simplex virus / Sleeping Beauty hybrid amplicon vectors. Current Gene Therapy. 11: 332-40. PMID 21711226 DOI: 10.2174/156652311797415845  0.619
2011 Bowers WJ, Breakefield XO, Sena-Esteves M. Genetic therapy for the nervous system. Human Molecular Genetics. 20: R28-41. PMID 21429918 DOI: 10.1093/Hmg/Ddr110  0.309
2011 Desai MK, Guercio BJ, Narrow WC, Bowers WJ. An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction. Glia. 59: 627-40. PMID 21294162 DOI: 10.1002/Glia.21131  0.714
2011 Philippidou P, Valdez G, Akmentin W, Bowers WJ, Federoff HJ, Halegoua S. Trk retrograde signaling requires persistent, Pincher-directed endosomes. Proceedings of the National Academy of Sciences of the United States of America. 108: 852-7. PMID 21187387 DOI: 10.1073/Pnas.1015981108  0.493
2011 Roher A, Bowers W, Hunter J, Maarouf C, Daugs I, Valla J, Kokjohn T, Beach T. P3-036: Morphological and biochemical analysis of the 3xTg-Alzheimer's disease mouse model: Implications for sporadic Alzheimer's disease and the amyloid cascade hypothesis Alzheimer's & Dementia. 7: S526-S526. DOI: 10.1016/J.Jalz.2011.05.1475  0.346
2010 Ryan DA, Mastrangelo MA, Narrow WC, Sullivan MA, Federoff HJ, Bowers WJ. Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1471-1481. PMID 28178507 DOI: 10.1038/mt.2010.111  0.689
2010 Lee BD, Shin JH, VanKampen J, Petrucelli L, West AB, Ko HS, Lee YI, Maguire-Zeiss KA, Bowers WJ, Federoff HJ, Dawson VL, Dawson TM. Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. Nature Medicine. 16: 998-1000. PMID 20729864 DOI: 10.1038/Nm.2199  0.489
2010 Desai MK, Mastrangelo MA, Ryan DA, Sudol KL, Narrow WC, Bowers WJ. Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target. The American Journal of Pathology. 177: 1422-35. PMID 20696774 DOI: 10.2353/Ajpath.2010.100087  0.788
2010 Kells AP, Eberling J, Su X, Pivirotto P, Bringas J, Hadaczek P, Narrow WC, Bowers WJ, Federoff HJ, Forsayeth J, Bankiewicz KS. Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9567-77. PMID 20631185 DOI: 10.1523/Jneurosci.0942-10.2010  0.614
2010 de Silva S, Lotta LT, Burris CA, Bowers WJ. Virion-associated cofactor high-mobility group DNA-binding protein-1 facilitates transposition from the herpes simplex virus/Sleeping Beauty amplicon vector platform. Human Gene Therapy. 21: 1615-22. PMID 20568967 DOI: 10.1089/Hum.2010.022  0.605
2010 Ryan DA, Mastrangelo MA, Narrow WC, Sullivan MA, Federoff HJ, Bowers WJ. Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1471-81. PMID 20551911 DOI: 10.1038/Mt.2010.111  0.709
2010 de Silva S, Mastrangelo MA, Lotta LT, Burris CA, Izsvák Z, Ivics Z, Bowers WJ. Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo. Human Gene Therapy. 21: 1603-13. PMID 20507234 DOI: 10.1089/Hum.2010.062  0.61
2010 Ryan DA, Narrow WC, Federoff HJ, Bowers WJ. An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies. Journal of Neuroscience Methods. 190: 171-9. PMID 20452375 DOI: 10.1016/J.Jneumeth.2010.05.001  0.681
2010 Xiong Y, Coombes CE, Kilaru A, Li X, Gitler AD, Bowers WJ, Dawson VL, Dawson TM, Moore DJ. GTPase activity plays a key role in the pathobiology of LRRK2. Plos Genetics. 6: e1000902. PMID 20386743 DOI: 10.1371/Journal.Pgen.1000902  0.332
2010 Park KM, Bowers WJ. Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction. Cellular Signalling. 22: 977-83. PMID 20096353 DOI: 10.1016/J.Cellsig.2010.01.010  0.503
2010 Park KM, Yule DI, Bowers WJ. Impaired TNF-alpha control of IP3R-mediated Ca2+ release in Alzheimer's disease mouse neurons. Cellular Signalling. 22: 519-26. PMID 19922794 DOI: 10.1016/J.Cellsig.2009.11.006  0.542
2010 de Silva S, Mastrangelo MA, Lotta LT, Burris CA, Federoff HJ, Bowers WJ. Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon-vector platform. Gene Therapy. 17: 424-31. PMID 19865178 DOI: 10.1038/Gt.2009.144  0.691
2010 Bowers WJ, Montogomery SL, Mastrangelo MA, Narrow WC. P1-318: Ablated TNF receptor expression differentially affects microglial activation and amyloid deposition in the 3xTg-AD mouse model Alzheimer's & Dementia. 6: S265-S266. DOI: 10.1016/J.Jalz.2010.05.871  0.347
2010 Bowers WJ, Desai MK, Mastrangelo MA, Ryan DA, Sudol KL, Narrow WC. P2-242: Oligodendrocyte cell lineage represents an amyloid beta 1-42 sensitive cell population leading to white matter alterations during early Alzheimer's disease Alzheimer's & Dementia. 6: S385-S385. DOI: 10.1016/J.Jalz.2010.05.1291  0.755
2009 Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2031-2040. PMID 28178451 DOI: 10.1038/mt.2009.174  0.532
2009 de Silva S, Bowers WJ. Herpes Virus Amplicon Vectors. Viruses. 1: 594-629. PMID 19956558 DOI: 10.3390/V1030594  0.597
2009 Mastrangelo MA, Sudol KL, Narrow WC, Bowers WJ. Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice. The American Journal of Pathology. 175: 2076-88. PMID 19808651 DOI: 10.2353/Ajpath.2009.090059  0.446
2009 Park KM, Yule DI, Bowers WJ. Tumor necrosis factor-alpha-mediated regulation of the inositol 1,4,5-trisphosphate receptor promoter. The Journal of Biological Chemistry. 284: 27557-66. PMID 19666470 DOI: 10.1074/Jbc.M109.034504  0.484
2009 Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2031-40. PMID 19638957 DOI: 10.1038/Mt.2009.174  0.562
2009 Chiu YG, Bowers WJ, Lim ST, Ryan DA, Federoff HJ. Effects of herpes simplex virus amplicon transduction on murine dendritic cells. Human Gene Therapy. 20: 442-52. PMID 19199821 DOI: 10.1089/Hum.2008.160  0.686
2009 Fiandaca MS, Varenika V, Eberling J, McKnight T, Bringas J, Pivirotto P, Beyer J, Hadaczek P, Bowers W, Park J, Federoff H, Forsayeth J, Bankiewicz KS. Real-time MR imaging of adeno-associated viral vector delivery to the primate brain Neuroimage. 47: T27-T35. PMID 19095069 DOI: 10.1016/J.Neuroimage.2008.11.012  0.51
2009 Daubeuf S, Singh D, Tan Y, Liu H, Federoff HJ, Bowers WJ, Tolba K. HSV ICP0 recruits USP7 to modulate TLR-mediated innate response. Blood. 113: 3264-75. PMID 18952891 DOI: 10.1182/Blood-2008-07-168203  0.525
2009 Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, Frazer ME, Bowers WJ. Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology. Glia. 57: 54-65. PMID 18661556 DOI: 10.1002/Glia.20734  0.765
2009 Federoff HJ, Chiu YG, Bowers WJ, Lim ST, Ryan DA. Effects of HSV amplicon transduction on murine dendritic cells Human Gene Therapy. 90126111624022. DOI: 10.1089/Hgt.2008.160  0.663
2008 Frazer ME, Hughes JE, Mastrangelo MA, Tibbens JL, Federoff HJ, Bowers WJ. Reduced Pathology and Improved Behavioral Performance in Alzheimer's Disease Mice Vaccinated With HSV Amplicons Expressing Amyloid-β and Interleukin-4. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 845-853. PMID 28178487 DOI: 10.1038/Mt.2008.39  0.594
2008 Janelsins MC, Mastrangelo MA, Park KM, Sudol KL, Narrow WC, Oddo S, LaFerla FM, Callahan LM, Federoff HJ, Bowers WJ. Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. The American Journal of Pathology. 173: 1768-82. PMID 18974297 DOI: 10.2353/Ajpath.2008.080528  0.733
2008 Park KM, Yule DI, Bowers WJ. Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor. The Journal of Biological Chemistry. 283: 33069-79. PMID 18838384 DOI: 10.1074/Jbc.M802209200  0.506
2008 Mastrangelo MA, Bowers WJ. Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. Bmc Neuroscience. 9: 81. PMID 18700006 DOI: 10.1186/1471-2202-9-81  0.386
2008 Frazer ME, Hughes JE, Mastrangelo MA, Tibbens JL, Federoff HJ, Bowers WJ. Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 845-53. PMID 18388924 DOI: 10.1038/mt.2008.39  0.538
2008 Burris CA, de Silva S, Narrow WC, Casey AE, Lotta LT, Federoff HJ, Bowers WJ. Hexamethylene bisacetamide leads to reduced helper virus-free HSV-1 amplicon expression titers via suppression of ICP0. The Journal of Gene Medicine. 10: 152-64. PMID 18058952 DOI: 10.1002/Jgm.1130  0.705
2008 Nechushtan H, Pham D, Zhang Y, Morgensztern D, Yi KH, Shin SU, Federoff HJ, Bowers WJ, Tolba KA, Rosenblatt JD. Augmentation of anti-tumor responses of adoptively transferred CD8+T cells in the lymphopenic setting by HSV amplicon transduction. Cancer Immunology, Immunotherapy : Cii. 57: 663-75. PMID 17952436 DOI: 10.1007/S00262-007-0405-1  0.52
2008 Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, Frazer ME, Bowers WJ. P3-404: Triple-transgenic Alzheimer's disease mice exhibit marked abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology Alzheimer's & Dementia. 4: T640-T640. DOI: 10.1016/J.Jalz.2008.05.1975  0.753
2008 Bowers WJ, Janelsins MC, Federoff HJ. Gene therapy and vaccination Neuroimmune Pharmacology. 709-724. DOI: 10.1007/978-0-387-72573-4_48  0.593
2007 Yi KH, Nechushtan H, Bowers WJ, Walker GR, Zhang Y, Pham DG, Podack ER, Federoff HJ, Tolba KA, Rosenblatt JD. Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo. Cancer Research. 67: 10027-37. PMID 17942937 DOI: 10.1158/0008-5472.Can-06-2391  0.54
2007 Duke CM, Maguire CA, Keefer MC, Federoff HJ, Bowers WJ, Dewhurst S. HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime. Vaccine. 25: 7410-21. PMID 17868958 DOI: 10.1016/J.Vaccine.2007.08.015  0.532
2007 Peterson EB, Mastrangelo MA, Federoff HJ, Bowers WJ. Neuronal specificity of HSV/sleeping beauty amplicon transduction in utero is driven primarily by tropism and cell type composition. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1848-55. PMID 17653102 DOI: 10.1038/Sj.Mt.6300267  0.596
2007 Santos K, Sanfilippo CM, Narrow WC, Casey AE, Rodriguez-Colon SM, McDermott MP, Federoff HJ, Bowers WJ, Dewhurst S. Infectivity of herpes simplex virus type-1 (HSV-1) amplicon vectors in dendritic cells is determined by the helper virus strain used for packaging. Journal of Virological Methods. 145: 37-46. PMID 17606303 DOI: 10.1016/J.Jviromet.2007.05.013  0.532
2007 Santos K, Simon DA, Conway E, Bowers WJ, Mitra S, Foster TH, Lugade A, Lord EM, Federoff HJ, Dewhurst S, Frelinger JG. Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. Human Gene Therapy. 18: 93-105. PMID 17298238 DOI: 10.1089/Hum.2006.082  0.607
2007 Sortwell CE, Bowers WJ, Counts SE, Pitzer MR, Fleming MF, McGuire SO, Maguire-Zeiss KA, Federoff HJ, Collier TJ. Effects of ex vivo transduction of mesencephalic reaggregates with bcl-2 on grafted dopamine neuron survival. Brain Research. 1134: 33-44. PMID 17196186 DOI: 10.1016/J.Brainres.2006.11.079  0.58
2007 Santos K, Duke CM, Rodriguez-Colon SM, Dakwar A, Fan S, Keefer MC, Federoff HJ, Frelinger JG, Bowers WJ, Dewhurst S. Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag. Vaccine. 25: 1634-46. PMID 17145123 DOI: 10.1016/J.Vaccine.2006.11.004  0.574
2007 Tan Y, Rosenblatt JD, Federoff HJ, Bowers WJ, Tolba KA. Regulation of TLR Signaling by USP7. Blood. 110: 2300-2300. DOI: 10.1182/Blood.V110.11.2300.2300  0.538
2006 Halterman MW, Giuliano RE, Bowers WJ, Federoff HJ. Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity. The Journal of Gene Medicine. 8: 1320-8. PMID 16989006 DOI: 10.1002/Jgm.972  0.746
2006 Tyler CM, Wuertzer CA, Bowers WJ, Federoff HJ. HSV amplicons: neuro applications. Current Gene Therapy. 6: 337-50. PMID 16787185 DOI: 10.2174/156652306777592045  0.779
2006 Bowers WJ, Mastrangelo MA, Howard DF, Southerland HA, Maguire-Zeiss KA, Federoff HJ. Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 580-8. PMID 16412694 DOI: 10.1016/J.Ymthe.2005.11.011  0.6
2006 Arvanian VL, Bowers WJ, Anderson A, Horner PJ, Federoff HJ, Mendell LM. Combined delivery of neurotrophin-3 and NMDA receptors 2D subunit strengthens synaptic transmission in contused and staggered double hemisected spinal cord of neonatal rat. Experimental Neurology. 197: 347-52. PMID 16289170 DOI: 10.1016/J.Expneurol.2005.10.008  0.478
2006 Tolba KA, Bowers W, Tan Y, Daubeuf S, Federoff HJ, Rosenblatt JD. HSV ICP0 Inhibits TLR-Mediated NF-κB Response to TLR Signaling. Blood. 108: 5487-5487. DOI: 10.1182/blood.v108.11.5487.5487  0.46
2006 Janelsins MC, Mastrangelo MA, Park KM, Fowlkes KL, Kinsky M, Narrow WC, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. 248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model Molecular Therapy. 13: S95. DOI: 10.1016/J.Ymthe.2006.08.275  0.7
2006 Fowlkes KL, Mastrangelo MA, Narrow WC, Levites Y, Golde TE, Federoff HJ, Bowers WJ. 247. Devising Aβ-Specific Passive Immunization Strategies for Alzheimer's Disease Using rAAV Vector-Mediated scFv Antibody Delivery Molecular Therapy. 13: S94-S95. DOI: 10.1016/J.Ymthe.2006.08.274  0.574
2005 Federoff HJ, Bowers WJ. Immune shaping and the development of Alzheimer's disease vaccines. Science of Aging Knowledge Environment : Sage Ke. 2005: pe35. PMID 16293586 DOI: 10.1126/Sageke.2005.46.Pe35  0.549
2005 Reinblatt M, Pin RH, Bowers WJ, Federoff HJ, Fong Y. Herpes simplex virus amplicon delivery of a hypoxia-inducible soluble vascular endothelial growth factor receptor (sFlk-1) inhibits angiogenesis and tumor growth in pancreatic adenocarcinoma. Annals of Surgical Oncology. 12: 1025-36. PMID 16244806 DOI: 10.1245/Aso.2005.03.081  0.517
2005 Janelsins MC, Mastrangelo MA, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. Journal of Neuroinflammation. 2: 23. PMID 16232318 DOI: 10.1186/1742-2094-2-23  0.689
2005 Corso TD, Torres G, Goulah C, Roy I, Gambino AS, Nayda J, Buckley T, Stachowiak EK, Bergey EJ, Pudavar H, Dutta P, Bloom DC, Bowers WJ, Stachowiak MK. Transfection of tyrosine kinase deleted FGF receptor-1 into rat brain substantia nigra reduces the number of tyrosine hydroxylase expressing neurons and decreases concentration levels of striatal dopamine. Brain Research. Molecular Brain Research. 139: 361-6. PMID 16039006 DOI: 10.1016/J.Molbrainres.2005.05.032  0.317
2005 Gorantla S, Santos K, Meyer V, Dewhurst S, Bowers WJ, Federoff HJ, Gendelman HE, Poluektova L. Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge. Journal of Virology. 79: 2124-32. PMID 15681415 DOI: 10.1128/Jvi.79.4.2124-2132.2005  0.532
2005 Bowers WJ, Mastrangelo MA, Stanley HA, Casey AE, Milo LJ, Federoff HJ. HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses. Neurobiology of Aging. 26: 393-407. PMID 15653168 DOI: 10.1016/J.Neurobiolaging.2004.04.006  0.578
2005 Daubeuf S, Rosenblatt JD, Bowers WJ, Federoff HJ, Tolba KA. HSV Encoded ICP-0 Inhibits TLR Signaling in CLL Cells by Targeting TRAF-6. Blood. 106: 2953-2953. DOI: 10.1182/Blood.V106.11.2953.2953  0.566
2005 Bowers WJ, Mastrangelo MA, Casey AE, Southerland HA, Maguire-Zeiss KA, Federoff HJ. 431. In Utero CNS Delivery of an Integrating HSV-1 Amplicon Vector Leads to Prolonged, Neuron-Specific Gene Expression Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.433  0.598
2004 Wang H, Yu SW, Koh DW, Lew J, Coombs C, Bowers W, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10963-73. PMID 15574746 DOI: 10.1523/Jneurosci.3461-04.2004  0.487
2004 Pin RH, Reinblatt M, Bowers WJ, Federoff HJ, Fong Y. Herpes simplex virus amplicon delivery of a hypoxia-inducible angiogenic inhibitor blocks capillary formation in hepatocellular carcinoma. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 8: 812-22; discussion 8. PMID 15531234 DOI: 10.1016/J.Gassur.2004.08.007  0.531
2004 Arvanian VL, Bowers WJ, Petruska JC, Motin V, Manuzon H, Narrow WC, Federoff HJ, Mendell LM. Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. Journal of Neurophysiology. 92: 2394-404. PMID 15152019 DOI: 10.1152/Jn.00278.2004  0.503
2004 Daubeuf S, Rosenblatt JD, Bowers WJ, Urbistondo NT, Federoff HJ, Tolba KA. HSV Amplicon Transduction Activates an Innate Immune Response in CLL B Cells;Implications for Immune Therapy and Vaccine Development. Blood. 104: 2514-2514. DOI: 10.1182/Blood.V104.11.2514.2514  0.566
2004 Bowers WJ, Mastrangelo MA, Stanley HA, Chiu Y, Federoff HJ. P4-340 Immunological assessment of acute CNS inflammatory processes elicited in an Alzheimer's disease mouse model following HSV amplicon-based Aβ vaccination Neurobiology of Aging. 25: S572. DOI: 10.1016/S0197-4580(04)81898-0  0.543
2004 Callahan LM, Edwards K, Maguire-Zeiss KA, Bowers WJ, Narrow WC, Kang S, Mastrangelo MA, Giuliano RE, Federoff HJ. P3-259 Expression of pathogenic tau, P301L, leads to microtubule disruption in hippocampal neurons Neurobiology of Aging. 25: S428. DOI: 10.1016/S0197-4580(04)81409-X  0.512
2004 Janelsins MC, Mastrangelo MA, Federoff HJ, Bowers WJ. 226. Developing a CNS-Specific Inflammatory Model To Investigate Gene Therapy/Inflammation Interactions in the Context of Neurodegeneration|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.170  0.71
2004 Stanley HA, Bowers WJ, Mastrangelo MA, Federoff HJ. 211. Creation of a HSV VP22-Sleeping Beauty Fusion Protein To Facilitate Integration of HSV-1 Amplicon Vectors|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.152  0.578
2004 Bowers WJ, Mastrangelo MA, Stanley HA, Chiu Y, Federoff HJ. 43. Immunological Response Characterization in an Alzheimer's Disease Mouse Model Following HSV Amplicon-Based A|[beta]| Vaccination|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.068  0.577
2003 Kyrkanides S, Miller Jn, Bowers WJ, Federoff HJ. Transcriptional and posttranslational regulation of Cre recombinase by RU486 as the basis for an enhanced inducible expression system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 790-5. PMID 14599812 DOI: 10.1016/J.Ymthe.2003.07.005  0.539
2003 Harvey BK, Chang CF, Chiang YH, Bowers WJ, Morales M, Hoffer BJ, Wang Y, Federoff HJ. HSV amplicon delivery of glial cell line-derived neurotrophic factor is neuroprotective against ischemic injury. Experimental Neurology. 183: 47-55. PMID 12957487 DOI: 10.1016/S0014-4886(03)00080-3  0.674
2003 Zhang Y, Hong Y, Bounhar Y, Blacker M, Roucou X, Tounekti O, Vereker E, Bowers WJ, Federoff HJ, Goodyer CG, LeBlanc A. p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7385-94. PMID 12917374 DOI: 10.1523/Jneurosci.23-19-07385.2003  0.49
2003 Bowers WJ, Olschowka JA, Federoff HJ. Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy. Gene Therapy. 10: 941-5. PMID 12756414 DOI: 10.1038/Sj.Gt.3302047  0.596
2003 Wang X, Wiley RD, Evans TG, Bowers WJ, Federoff HJ, Dewhurst S. Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming. Vaccine. 21: 2288-97. PMID 12744859 DOI: 10.1016/S0264-410X(03)00099-9  0.528
2003 Olschowka JA, Bowers WJ, Hurley SD, Mastrangelo MA, Federoff HJ. Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 218-27. PMID 12597910 DOI: 10.1016/S1525-0016(02)00036-9  0.609
2003 Snyder JE, Bowers WJ, Livingstone AM, Lee FE, Federoff HJ, Mosmann TR. Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing. Nature Medicine. 9: 231-5. PMID 12539041 DOI: 10.1038/Nm821  0.56
2002 Wang SW, Mu X, Bowers WJ, Klein WH. Retinal ganglion cell differentiation in cultured mouse retinal explants. Methods (San Diego, Calif.). 28: 448-56. PMID 12507463 DOI: 10.1016/S1046-2023(02)00264-5  0.351
2002 Tolba KA, Bowers WJ, Muller J, Housekneckt V, Giuliano RE, Federoff HJ, Rosenblatt JD. Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activity. Cancer Research. 62: 6545-51. PMID 12438249  0.496
2002 Maguire-Zeiss KA, Bowers WJ, Federoff HJ. Somatic mosaic approaches and the aging brain. Neurobiology of Aging. 23: 977-84. PMID 12392799 DOI: 10.1016/S0197-4580(02)00077-5  0.54
2002 Bowers WJ, Federoff HJ. Amyloid immunotherapy-engendered CNS inflammation. Neurobiology of Aging. 23: 675-6; discussion 68. PMID 12392770 DOI: 10.1016/S0197-4580(02)00035-0  0.529
2002 Tolba KA, Bowers WJ, Eling DJ, Casey AE, Kipps TJ, Federoff HJ, Rosenblatt JD. HSV amplicon-mediated delivery of LIGHT enhances the antigen-presenting capacity of chronic lymphocytic leukemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 455-63. PMID 12377186 DOI: 10.1006/Mthe.2002.0693  0.549
2002 Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science (New York, N.Y.). 297: 259-63. PMID 12114629 DOI: 10.1126/Science.1072221  0.486
2002 Bowers WJ, Chen X, Guo H, Frisina DR, Federoff HJ, Frisina RD. Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 12-8. PMID 12095298 DOI: 10.1006/Mthe.2002.0627  0.581
2002 Detrait ER, Bowers WJ, Halterman MW, Giuliano RE, Bennice L, Federoff HJ, Richfield EK. Reporter gene transfer induces apoptosis in primary cortical neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 723-30. PMID 12027556 DOI: 10.1006/Mthe.2002.0609  0.734
2002 Hocknell PK, Wiley RD, Wang X, Evans TG, Bowers WJ, Hanke T, Federoff HJ, Dewhurst S. Expression of human immunodeficiency virus type 1 gp120 from herpes simplex virus type 1-derived amplicons results in potent, specific, and durable cellular and humoral immune responses. Journal of Virology. 76: 5565-80. PMID 11991985 DOI: 10.1128/Jvi.76.11.5565-5580.2002  0.557
2002 Halaby IA, Lyden SP, Davies MG, Roztocil E, Salamone LJ, Brooks AI, Green RM, Federoff HJ, Bowers WJ. Glucocorticoid-regulated VEGF expression in ischemic skeletal muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 300-6. PMID 11863420 DOI: 10.1006/Mthe.2002.0539  0.517
2002 Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH. Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development (Cambridge, England). 129: 467-77. PMID 11807038  0.438
2001 Maguire-Zeiss KA, Bowers WJ, Federoff HJ. HSV vector-mediated gene delivery to the central nervous system. Current Opinion in Molecular Therapeutics. 3: 482-90. PMID 11699893  0.549
2001 Willis RA, Bowers WJ, Turner MJ, Fisher TL, Abdul-Alim CS, Howard DF, Federoff HJ, Lord EM, Frelinger JG. Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice. Human Gene Therapy. 12: 1867-79. PMID 11589829 DOI: 10.1089/104303401753153929  0.563
2001 Ballas N, Battaglioli E, Atouf F, Andres ME, Chenoweth J, Anderson ME, Burger C, Moniwa M, Davie JR, Bowers WJ, Federoff HJ, Rose DW, Rosenfeld MG, Brehm P, Mandel G. Regulation of neuronal traits by a novel transcriptional complex. Neuron. 31: 353-65. PMID 11516394 DOI: 10.1016/S0896-6273(01)00371-3  0.525
2001 Tolba KA, Bowers WJ, Hilchey SP, Halterman MW, Howard DF, Giuliano RE, Federoff HJ, Rosenblatt JD. Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia. Blood. 98: 287-95. PMID 11435295 DOI: 10.1182/Blood.V98.2.287  0.737
2001 Chen X, Frisina RD, Bowers WJ, Frisina DR, Federoff HJ. HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 958-63. PMID 11407910 DOI: 10.1006/Mthe.2001.0334  0.592
2001 Bowers WJ, Howard DF, Brooks AI, Halterman MW, Federoff HJ. Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers. Gene Therapy. 8: 111-20. PMID 11313780 DOI: 10.1038/Sj.Gt.3301340  0.74
2001 Jackson M, Song W, Liu MY, Jin L, Dykes-Hoberg M, Lin CI, Bowers WJ, Federoff HJ, Sternweis PC, Rothstein JD. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature. 410: 89-93. PMID 11242047 DOI: 10.1038/35065091  0.474
2001 Bowers WJ, Maguire-Zeiss KA, Harvey BK, Federoff HJ. Gene therapeutic approaches to the treatment of Parkinson's disease Clinical Neuroscience Research. 1: 483-495. DOI: 10.1016/S1566-2772(01)00026-3  0.676
2000 Brooks AI, Cory-Slechta DA, Bowers WJ, Murg SL, Federoff HJ. Enhanced learning in mice parallels vector-mediated nerve growth factor expression in hippocampus. Human Gene Therapy. 11: 2341-52. PMID 11096439 DOI: 10.1089/104303400750038453  0.497
2000 Bowers WJ, Howard DF, Federoff HJ. Discordance between expression and genome transfer titering of HSV amplicon vectors: recommendation for standardized enumeration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 294-9. PMID 10933945 DOI: 10.1006/Mthe.2000.0039  0.592
1999 Tolba K, Federoff HJ, Bowers W, Facciponte J, Baka J, Challita-Eid P, Rosenblatt JD. Helper-Free Herpes Simplex Virus Amplicons allow Efficient Transduction of Leukemia Cells with a costimulatory ligand without Loss of MHC-I Expression Journla of Immunotherapy. 22: 466. DOI: 10.1097/00002371-199909000-00058  0.549
1997 Baglia LA, Bowers WJ, Ruddell A. The avian C/EBPgamma gene encodes a highly conserved leucine zipper transcription factor. Gene. 190: 297-302. PMID 9197547 DOI: 10.1016/S0378-1119(97)00016-4  0.651
1997 Bowers WJ, Howard DF, Federoff HJ. Gene therapeutic strategies for neuroprotection: implications for Parkinson's disease. Experimental Neurology. 144: 58-68. PMID 9126153 DOI: 10.1006/Exnr.1996.6389  0.585
1996 Bowers WJ, Baglia LA, Ruddel A. Regulation of avian leukosis virus long terminal repeat-enhanced transcription by C/EBP-Rel interactions. Journal of Virology. 70: 3051-9. PMID 8627783 DOI: 10.1128/Jvi.70.5.3051-3059.1996  0.329
1994 Bowers WJ, Petrosino JF, Smith CD, Ruddell A. Transcriptional regulation of ALV bursal lymphomagenesis. Leukemia. 8: S211-3. PMID 8152295  0.609
1992 Bowers WJ, Ruddell A. a1/EBP: a leucine zipper protein that binds CCAAT/enhancer elements in the avian leukosis virus long terminal repeat enhancer. Journal of Virology. 66: 6578-86. PMID 1328681 DOI: 10.1128/Jvi.66.11.6578-6586.1992  0.635
Low-probability matches (unlikely to be authored by this person)
2014 Evans EE, Bussler H, Torno S, Veeraraghavan J, Jonason AS, Doherty MA, Reilly C, Mallow C, Seils J, Paris M, Fisher TL, Bowers WJ, Scrivens M, Balch L, Kirk R, et al. Abstract 5030: Antibody blockade of Semaphorin 4D promotes tumor rejection and improves response to immune checkpoint blockade and chemotherapy Cancer Research. 74: 5030-5030. DOI: 10.1158/1538-7445.Am2014-5030  0.3
2015 Evans EE, Fisher TL, Edington C, Bussler H, Torno S, Jonason AS, Veeraraghavan J, Reilly C, Doherty MA, Seils J, Winter LA, Pandina T, Mallow C, Kirk R, Howell A, ... ... Bowers WJ, et al. Abstract A67: Phase 1 study of VX15/2503, an immunomodulatory antibody to Semaphorin 4D that reverses tumor growth in preclinical studies Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-A67  0.299
2009 Bancos S, Cao Q, Bowers WJ, Crispe IN. Dysfunctional memory CD8+ T cells after priming in the absence of the cell cycle regulator E2F4. Cellular Immunology. 257: 44-54. PMID 19306992 DOI: 10.1016/J.Cellimm.2009.02.006  0.298
2011 García-Alías G, Petrosyan HA, Schnell L, Horner PJ, Bowers WJ, Mendell LM, Fawcett JW, Arvanian VL. Chondroitinase ABC combined with neurotrophin NT-3 secretion and NR2D expression promotes axonal plasticity and functional recovery in rats with lateral hemisection of the spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17788-99. PMID 22159095 DOI: 10.1523/Jneurosci.4308-11.2011  0.295
2007 Azadniv M, Dugger K, Bowers WJ, Weaver C, Crispe IN. Imaging CD8+ T cell dynamics in vivo using a transgenic luciferase reporter. International Immunology. 19: 1165-73. PMID 17698980 DOI: 10.1093/Intimm/Dxm086  0.289
2008 Park KM, Yule DI, Bowers WJ. P3-370: Tumor necrosis factor-alpha potentiates neuronal muscarinic Ca2+ signals via regulation of inositol 1,4,5-trisphosphate receptor expression Alzheimer's & Dementia. 4: T630-T630. DOI: 10.1016/J.Jalz.2008.05.1940  0.279
2014 Rappold PM, Cui M, Grima JC, Fan RZ, de Mesy-Bentley KL, Chen L, Zhuang X, Bowers WJ, Tieu K. Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo. Nature Communications. 5: 5244. PMID 25370169 DOI: 10.1038/Ncomms6244  0.266
2005 Corso TD, Torres G, Goulah C, Roy I, Gambino AS, Nayda J, Buckley T, Stachowiak EK, Bergey EJ, Pudavar H, Dutta P, Bloom DC, Bowers WJ, Stachowiak MK. Assessment of viral and non-viral gene transfer into adult rat brains using HSV-1, calcium phosphate and PEI-based methods. Folia Morphologica. 64: 130-44. PMID 16228947  0.256
2011 Azadniv M, Bowers WJ, Topham DJ, Crispe IN. CD4+ T cell effects on CD8+ T cell location defined using bioluminescence. Plos One. 6: e16222. PMID 21283759 DOI: 10.1371/Journal.Pone.0016222  0.245
2002 Mankodi A, Takahashi MP, Jiang H, Beck CL, Bowers WJ, Moxley RT, Cannon SC, Thornton CA. Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy. Molecular Cell. 10: 35-44. PMID 12150905 DOI: 10.1016/S1097-2765(02)00563-4  0.235
2010 Fong S, Chan MK, Fong A, Bowers WJ, Kelly KJ. Viral vector-induced expression of bone morphogenetic protein 2 produces inhibition of tumor growth and bone differentiation of stem cells. Cancer Gene Therapy. 17: 80-5. PMID 19834515 DOI: 10.1038/cgt.2009.56  0.183
2008 Padhi BK, Pelletier G, Williams A, Berndt-Weis L, Yauk C, Bowers WJ, Chu I. Gene expression profiling in rat cerebellum following in utero and lactational exposure to mixtures of methylmercury, polychlorinated biphenyls and organochlorine pesticides. Toxicology Letters. 176: 93-103. PMID 18077114 DOI: 10.1016/J.Toxlet.2007.08.016  0.176
2009 Pelletier G, Masson S, Wade MJ, Nakai J, Alwis R, Mohottalage S, Kumarathasan P, Black P, Bowers WJ, Chu I, Vincent R. Contribution of methylmercury, polychlorinated biphenyls and organochlorine pesticides to the toxicity of a contaminant mixture based on Canadian Arctic population blood profiles. Toxicology Letters. 184: 176-85. PMID 19059321 DOI: 10.1016/J.Toxlet.2008.11.004  0.135
2015 Chepelev NL, Moffat ID, Bowers WJ, Yauk CL. Neurotoxicity may be an overlooked consequence of benzo[a]pyrene exposure that is relevant to human health risk assessment. Mutation Research. Reviews in Mutation Research. 764: 64-89. PMID 26041267 DOI: 10.1016/J.Mrrev.2015.03.001  0.12
2013 Gill S, Bowers WJ, Nakai JS, Yagminas A, Mueller R, Pulido O. Effects of environmentally relevant mixtures of persistent organic pollutants on the developmental neurobiology in rats. Toxicologic Pathology. 41: 38-47. PMID 22872703 DOI: 10.1177/0192623312451370  0.119
1984 Zacharko RM, Bowers WJ, Kelley MS, Anisman H. Prevention of stressor-induced disturbances of self-stimulation by desmethylimipramine. Brain Research. 321: 175-9. PMID 6541958 DOI: 10.1016/0006-8993(84)90697-8  0.112
2011 Hayley S, Mangano E, Crowe G, Li N, Bowers WJ. An in vivo animal study assessing long-term changes in hypothalamic cytokines following perinatal exposure to a chemical mixture based on Arctic maternal body burden. Environmental Health : a Global Access Science Source. 10: 65. PMID 21745392 DOI: 10.1186/1476-069X-10-65  0.111
1996 Bowers WJ, Gingras MA, Amit Z. Time-dependent exacerbation of amphetamine-induced taste aversions following exposure to footshock. Psychopharmacology. 125: 43-9. PMID 8724447 DOI: 10.1007/Bf02247391  0.084
2011 Black P, Niu L, Sachdeva M, Lean D, Poon R, Bowers WJ, Chan HM, Arnason JT, Pelletier G. Modulation of the effects of methylmercury on rat neurodevelopment by co-exposure with Labrador Tea (Rhododendron tomentosum ssp. subarcticum). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 49: 2336-42. PMID 21722698 DOI: 10.1016/J.Fct.2011.06.035  0.08
1984 Zacharko RM, Bowers WJ, Anisman H. Responding for brain stimulation: stress and desmethylimipramine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 8: 601-6. PMID 6543396 DOI: 10.1016/0278-5846(84)90021-6  0.079
2009 Desaulniers D, Xiao GH, Lian H, Feng YL, Zhu J, Nakai J, Bowers WJ. Effects of mixtures of polychlorinated biphenyls, methylmercury, and organochlorine pesticides on hepatic DNA methylation in prepubertal female Sprague-Dawley rats. International Journal of Toxicology. 28: 294-307. PMID 19636072 DOI: 10.1177/1091581809337918  0.071
2005 Chu I, Bowers WJ, Caldwell D, Nakai J, Pulido O, Yagminas A, Wade MG, Moir D, Gill S, Mueller R. Toxicological effects of gestational and lactational exposure to a mixture of persistent organochlorines in rats: systemic effects. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 645-55. PMID 16177236 DOI: 10.1093/Toxsci/Kfi335  0.071
2002 Seegal RF, Bowers WJ. Consequences and mechanisms of action of fish-borne toxicants: what we do not know and why. Environmental Toxicology and Pharmacology. 12: 63-8. PMID 21782624 DOI: 10.1016/S1382-6689(02)00023-6  0.071
1983 Zacharko RM, Bowers WJ, Kokkinidis L, Anisman H. Region-specific reductions of intracranial self-stimulation after uncontrollable stress: possible effects on reward processes. Behavioural Brain Research. 9: 129-41. PMID 6603854 DOI: 10.1016/0166-4328(83)90123-7  0.067
2011 Elabbas LE, Finnilä MA, Herlin M, Stern N, Trossvik C, Bowers WJ, Nakai J, Tuukkanen J, Heimeier RA, Ã…kesson A, HÃ¥kansson H. Perinatal exposure to environmental contaminants detected in Canadian Arctic human populations changes bone geometry and biomechanical properties in rat offspring. Journal of Toxicology and Environmental Health. Part A. 74: 1304-18. PMID 21830859 DOI: 10.1080/15287394.2011.590103  0.063
2015 Bowers WJ, Wall PM, Nakai JS, Yagminas A, Wade M, Li N, Chu I. Behavioural and thyroid effects of in utero and lactational exposure of Sprague Dawley rats to the polybrominated diphenyl ethers mixture DE71. Neurotoxicology and Teratology. PMID 26271887 DOI: 10.1016/J.Ntt.2015.08.002  0.062
2008 Chu I, Bowers WJ, Caldwell D, Nakai J, Wade MG, Yagminas A, Li N, Moir D, El Abbas L, HÃ¥kansson H, Gill S, Mueller R, Pulido O. Toxicological effects of in utero and lactational exposure of rats to a mixture of environmental contaminants detected in Canadian Arctic human populations. Journal of Toxicology and Environmental Health. Part A. 71: 93-108. PMID 18080900 DOI: 10.1080/15287390701612811  0.054
2009 Makris SL, Raffaele K, Allen S, Bowers WJ, Hass U, Alleva E, Calamandrei G, Sheets L, Amcoff P, Delrue N, Crofton KM. A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426. Environmental Health Perspectives. 117: 17-25. PMID 19165382 DOI: 10.1289/Ehp.11447  0.054
2004 Bowers WJ, Nakai JS, Chu I, Wade MG, Moir D, Yagminas A, Gill S, Pulido O, Meuller R. Early developmental neurotoxicity of a PCB/organochlorine mixture in rodents after gestational and lactational exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 77: 51-62. PMID 14514954 DOI: 10.1093/Toxsci/Kfg248  0.054
2005 Chu I, Poon R, Valli V, Yagminas A, Bowers WJ, Seegal R, Vincent R. Effects of an ethanol-gasoline mixture: results of a 4-week inhalation study in rats. Journal of Applied Toxicology : Jat. 25: 193-9. PMID 15856534 DOI: 10.1002/Jat.1051  0.053
2011 Elabbas LE, Herlin M, Finnilä MA, Rendel F, Stern N, Trossvik C, Bowers WJ, Nakai J, Tuukkanen J, Viluksela M, Heimeier RA, Akesson A, HÃ¥kansson H. In utero and lactational exposure to Aroclor 1254 affects bone geometry, mineral density and biomechanical properties of rat offspring. Toxicology Letters. 207: 82-8. PMID 21856390 DOI: 10.1016/J.Toxlet.2011.08.003  0.05
2014 Elabbas LE, Esteban J, Barber X, Hamscher G, Nau H, Bowers WJ, Nakai JS, Herlin M, Ã…kesson A, Viluksela M, Borg D, HÃ¥kansson H. In utero and lactational exposure to a mixture of environmental contaminants detected in Canadian Arctic human populations alters retinoid levels in rat offspring with low margins of exposure. Journal of Toxicology and Environmental Health. Part A. 77: 223-45. PMID 24588224 DOI: 10.1080/15287394.2013.861776  0.049
1999 Bowers WJ, Attiast E, Amit Z. Stress enhances the response to reward reduction but not food-motivated responding. Physiology & Behavior. 67: 777-82. PMID 10604850 DOI: 10.1016/S0031-9384(99)00129-8  0.048
1987 Bowers WJ, Zacharko RM, Anisman H. Evaluation of stressor effects on intracranial self-stimulation from the nucleus accumbens and the substantia nigra in a current intensity paradigm. Behavioural Brain Research. 23: 85-93. PMID 3828048 DOI: 10.1016/0166-4328(87)90245-2  0.048
2012 Desaulniers D, Leingartner K, Pelletier G, Xiao GH, Bowers WJ. Effects of developmental exposure to mixtures of environmental contaminants on the hepatic metabolism of estradiol-17β in immature female Sprague Dawley rats. International Journal of Toxicology. 31: 454-66. PMID 22914890 DOI: 10.1177/1091581812457431  0.044
1993 Heagerty A, Fryer A, Alldersea J, Zhao L, Smith A, Bowers W, Strange R. Xenobiotics are important in skin tumorigenesis: Evidence from studies of glutathione S-transferase genotype deletion Journal of Dermatological Science. 6: 85. DOI: 10.1016/0923-1811(93)91208-C  0.039
2010 Bowers WJ, Olson DA. A capacitive probe for measuring the clearance between the piston and the cylinder of a gas piston gauge. The Review of Scientific Instruments. 81: 035102. PMID 20370208 DOI: 10.1063/1.3310092  0.036
2015 Wong Kee Song LM, Gostout CJ, Tucker RD, Morris ML, Bowers WJ, Cattau EL. Electrosurgery in Gastrointestinal Endoscopy: Terminology Matters. Gastrointestinal Endoscopy. PMID 26264432 DOI: 10.1016/j.gie.2015.08.002  0.031
2014 Esteban J, Elabbas LE, Borg D, Herlin M, Ã…kesson A, Barber X, Hamscher G, Nau H, Bowers WJ, Nakai JS, Viluksela M, HÃ¥kansson H. Gestational and lactational exposure to the polychlorinated biphenyl mixture Aroclor 1254 modulates retinoid homeostasis in rat offspring. Toxicology Letters. 229: 41-51. PMID 24887809 DOI: 10.1016/j.toxlet.2014.04.021  0.029
2001 Wirt DP, Bailey WC, Bowers WJ. Physicians' attitudes about involvement in lethal injection for capital punishment. Archives of Internal Medicine. 161: 1353-4. PMID 11371272  0.028
1986 Bowers WJ, Givelber DJ, Blitch CL. How did Tarasoff affect clinical practice? The Annals of the American Academy of Political and Social Science. 70-85. PMID 11616565  0.027
1986 Bowers WJ, Givelber DJ, Blitch CL. How did Tarasoff affect clinical practice? The Annals of the American Academy of Political and Social Science. 70-85. PMID 10276576  0.027
1975 Bowers WJ, Pierce GL. The Illusion of Deterrence in Isaac Ehrlich's Research on Capital Punishment The Yale Law Journal. 85: 187. DOI: 10.2307/795412  0.026
1997 Bowers WJ, Sabongui AG, Amit Z. The role of ethanol availability on stress-induced increases in ethanol consumption. Alcohol (Fayetteville, N.Y.). 14: 551-6. PMID 9401669 DOI: 10.1016/S0741-8329(96)00046-8  0.025
1999 Gillespie WD, Hahn JW, Bowers WJ, Hurst WS, Rosasco GJ. Broadband D2 coherent anti-stokes Raman spectroscopy for single-shot pressure and temperature determination with a Fabry-Perot etalon. Applied Optics. 38: 534-44. PMID 18305643  0.018
1982 Van Degrift CT, Bowers WJ, Pipes PB, McQueeney DF. Contribution of Nuclear Magnetism to the Isochoric Pressure of bcc SolidHe3 Physical Review Letters. 49: 149-153. DOI: 10.1103/PHYSREVLETT.49.149  0.013
1985 Minor WW, Bowers WJ, Pierce GL, McDevitt JF, van den Haag E, Conrad JP. Review Essay: Reflections on the Killing of Criminals The Journal of Criminal Law and Criminology (1973-). 76: 764. DOI: 10.2307/1143522  0.01
1984 Givelber DJ, Bowers WJ, Blitch CL. Tarasoff, myth and reality: an empirical study of private law in action. Wisconsin Law Review. 1984: 443-97. PMID 11653756  0.01
1968 Bowers WJ. Normative constraints on deviant behavior in the college context. Sociometry. 31: 370-85. PMID 5702469  0.01
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