| Year |
Citation |
Score |
| 2024 |
Carruthers VB, Dou Z. Deciphering protein prenylation in endocytic trafficking in . Mbio. e0028324. PMID 38407123 DOI: 10.1128/mbio.00283-24 |
0.489 |
|
| 2023 |
Wang F, Holmes MJ, Hong HJ, Thaprawat P, Kannan G, Huynh MH, Schultz TL, Licon MH, Lourido S, Sullivan WJ, O'Leary SE, Carruthers VB. Translation initiation factor eIF1.2 promotes stage conversion by regulating levels of key differentiation factors. Biorxiv : the Preprint Server For Biology. PMID 37961607 DOI: 10.1101/2023.11.03.565545 |
0.657 |
|
| 2023 |
Valleau D, Sidik SM, Godoy LC, Acevedo-Sánchez Y, Pasaje CFA, Huynh MH, Carruthers VB, Niles JC, Lourido S. A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma. The Embo Journal. e113155. PMID 37886905 DOI: 10.15252/embj.2022113155 |
0.756 |
|
| 2023 |
Piro F, Masci S, Kannan G, Focaia R, Schultz TL, Carruthers VB, Di Cristina M. A putative arginine transporter localizes to the plant-like vacuolar compartment and controls parasite extracellular survival and stage differentiation. Biorxiv : the Preprint Server For Biology. PMID 37693549 DOI: 10.1101/2023.08.31.555807 |
0.332 |
|
| 2023 |
Aghabi D, Sloan M, Gill G, Hartmann E, Antipova O, Dou Z, Guerra AJ, Carruthers VB, Harding CR. The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii. Nature Communications. 14: 3659. PMID 37339985 DOI: 10.1038/s41467-023-39436-y |
0.705 |
|
| 2023 |
Rivera-Cuevas Y, Carruthers VB. The multifaceted interactions between pathogens and host ESCRT machinery. Plos Pathogens. 19: e1011344. PMID 37141275 DOI: 10.1371/journal.ppat.1011344 |
0.438 |
|
| 2023 |
Romano PS, Akematsu T, Besteiro S, Bindschedler A, Carruthers VB, Chahine Z, Coppens I, Descoteaux A, Alberto Duque TL, He CY, Heussler V, Le Roch KG, Li FJ, de Menezes JPB, Menna-Barreto RFS, et al. Autophagy in protists and their hosts: When, how and why? Autophagy Reports. 2. PMID 37064813 DOI: 10.1080/27694127.2022.2149211 |
0.393 |
|
| 2023 |
Koreny L, Mercado-Saavedra BN, Klinger CM, Barylyuk K, Butterworth S, Hirst J, Rivera-Cuevas Y, Zaccai NR, Holzer VJC, Klingl A, Dacks JB, Carruthers VB, Robinson MS, Gras S, Waller RF. Stable endocytic structures navigate the complex pellicle of apicomplexan parasites. Nature Communications. 14: 2167. PMID 37061511 DOI: 10.1038/s41467-023-37431-x |
0.366 |
|
| 2023 |
Montano H, Anandkrishnan R, Carruthers VB, Gaji RY. TgTKL4 Is a Novel Kinase That Plays an Important Role in Morphology and Fitness. Msphere. e0064922. PMID 36786615 DOI: 10.1128/msphere.00649-22 |
0.407 |
|
| 2023 |
Romano JD, Mayoral J, Guevara RB, Rivera-Cuevas Y, Carruthers VB, Weiss LM, Coppens I. Toxoplasma scavenges mammalian host organelles through the usurpation of host ESCRT-III and Vps4. Journal of Cell Science. PMID 36718630 DOI: 10.1242/jcs.260159 |
0.457 |
|
| 2021 |
Rivera-Cuevas Y, Mayoral J, Di Cristina M, Lawrence AE, Olafsson EB, Patel RK, Thornhill D, Waldman BS, Ono A, Sexton JZ, Lourido S, Weiss LM, Carruthers VB. Toxoplasma gondii exploits the host ESCRT machinery for parasite uptake of host cytosolic proteins. Plos Pathogens. 17: e1010138. PMID 34898650 DOI: 10.1371/journal.ppat.1010138 |
0.759 |
|
| 2021 |
Huynh MH, Roiko MS, Gomes AO, Schinke EN, Schultz AJ, Agrawal S, Oellig CA, Sexton TR, Beauchamp JM, Laliberté J, Sivaraman KK, Hersh LB, McGowan S, Carruthers VB. Toxolysin 4 Contributes to Efficient Parasite Egress from Host Cells. Msphere. e0044421. PMID 34190588 DOI: 10.1128/mSphere.00444-21 |
0.526 |
|
| 2021 |
Kannan G, Thaprawat P, Schultz TL, Carruthers VB. Acquisition of Host Cytosolic Protein by Toxoplasma gondii Bradyzoites. Msphere. 6. PMID 33504659 DOI: 10.1128/mSphere.00934-20 |
0.483 |
|
| 2021 |
McGovern OL, Rivera-Cuevas Y, Carruthers VB. Emerging Mechanisms of Endocytosis in . Life (Basel, Switzerland). 11. PMID 33503859 DOI: 10.3390/life11020084 |
0.355 |
|
| 2020 |
Young JC, Broncel M, Teague H, Russell MRG, McGovern OL, Renshaw M, Frith D, Snijders AP, Collinson L, Carruthers VB, Ewald SE, Treeck M. Phosphorylation of Secreted Proteins during Acute and Chronic Stages of Infection. Msphere. 5. PMID 32907954 DOI: 10.1128/mSphere.00792-20 |
0.415 |
|
| 2020 |
McDonald C, Smith D, Di Cristina M, Kannan G, Dou Z, Carruthers VB. Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion. Msphere. 5. PMID 32051238 DOI: 10.1128/mSphere.00869-19 |
0.364 |
|
| 2020 |
Zwicker JD, Smith D, Guerra AJ, Hitchens JR, Haug N, Vander Roest S, Lee P, Wen B, Sun D, Wang L, Keep R, Xiang J, Carruthers VB, Larsen SD. Discovery and Optimization of Triazine Nitrile Inhibitors of Toxoplasma gondii Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS. Acs Chemical Neuroscience. PMID 32027110 DOI: 10.1021/Acschemneuro.9B00674 |
0.731 |
|
| 2020 |
Mayoral J, Di Cristina M, Carruthers VB, Weiss LM. Toxoplasma gondii: Bradyzoite Differentiation In Vitro and In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2071: 269-282. PMID 31758458 DOI: 10.1007/978-1-4939-9857-9_15 |
0.301 |
|
| 2019 |
Kannan G, Di Cristina M, Schultz AJ, Huynh MH, Wang F, Schultz TL, Lunghi M, Coppens I, Carruthers VB. Role of Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance. Mbio. 10. PMID 31387907 DOI: 10.1128/mBio.01324-19 |
0.375 |
|
| 2019 |
Carruthers VB. Interrupting Toxoplasma's Regularly Scheduled Program of Egress. Trends in Parasitology. PMID 30948349 DOI: 10.1016/j.pt.2019.03.007 |
0.302 |
|
| 2018 |
Khurana S, Coffey MJ, John A, Uboldi AD, Huynh MH, Stewart RJ, Carruthers V, Tonkin CJ, Goddard-Borger ED, Scott NE. Protein O-fucosyltransferase 2-mediated O-glycosylation of the adhesin MIC2 is dispensable for Toxoplasma gondii tachyzoite infection. The Journal of Biological Chemistry. PMID 30514763 DOI: 10.1074/jbc.RA118.005357 |
0.316 |
|
| 2018 |
Guerra AJ, Zhang O, Bahr CME, Huynh MH, DelProposto J, Brown WC, Wawrzak Z, Koropatkin NM, Carruthers VB. Structural basis of toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress. Plos Pathogens. 14: e1007476. PMID 30513119 DOI: 10.1371/Journal.Ppat.1007476 |
0.763 |
|
| 2018 |
Zwicker JD, Diaz NA, Guerra AJ, Kirchhoff PD, Wen B, Sun D, Carruthers VB, Larsen SD. Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability. Bioorganic & Medicinal Chemistry Letters. PMID 29650289 DOI: 10.1016/J.Bmcl.2018.03.020 |
0.714 |
|
| 2018 |
Schultz AJ, Carruthers VB.
LCAT Primarily Contributes to Tachyzoite Egress. Msphere. 3. PMID 29507893 DOI: 10.1128/mSphereDirect.00073-18 |
0.415 |
|
| 2018 |
McGovern OL, Rivera-Cuevas Y, Kannan G, Narwold A, Carruthers VB. Intersection of Endocytic and Exocytic Systems in Toxoplasma gondii. Traffic (Copenhagen, Denmark). PMID 29437275 DOI: 10.1111/tra.12556 |
0.477 |
|
| 2017 |
Guerra AJ, Carruthers VB. Structural Features of Apicomplexan Pore-Forming Proteins and Their Roles in Parasite Cell Traversal and Egress. Toxins. 9. PMID 28850082 DOI: 10.3390/Toxins9090265 |
0.811 |
|
| 2017 |
Di Cristina M, Dou Z, Lunghi M, Kannan G, Huynh MH, McGovern OL, Schultz TL, Schultz AJ, Miller AJ, Hayes BM, van der Linden W, Emiliani C, Bogyo M, Besteiro S, Coppens I, ... Carruthers VB, et al. Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection. Nature Microbiology. 2: 17096. PMID 28628099 DOI: 10.1038/Nmicrobiol.2017.96 |
0.329 |
|
| 2016 |
Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JP, Carruthers VB, Niles JC, Lourido S. A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Cell. PMID 27594426 DOI: 10.1016/J.Cell.2016.08.019 |
0.696 |
|
| 2016 |
Huynh MH, Carruthers VB. A Toxoplasma gondii Ortholog of Plasmodium GAMA Contributes to Parasite Attachment and Cell Invasion. Msphere. 1. PMID 27303694 DOI: 10.1128/mSphere.00012-16 |
0.517 |
|
| 2016 |
McGovern OL, Carruthers VB. Toxoplasma Retromer Is Here to Stay. Trends in Parasitology. PMID 27247246 DOI: 10.1016/j.pt.2016.05.007 |
0.394 |
|
| 2016 |
Bullen HE, Jia Y, Yamaryo-Botté Y, Bisio H, Zhang O, Jemelin NK, Marq JB, Carruthers V, Botté CY, Soldati-Favre D. Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in Toxoplasma. Cell Host & Microbe. 19: 349-60. PMID 26962945 DOI: 10.1016/J.Chom.2016.02.006 |
0.409 |
|
| 2015 |
Pszenny V, Ehrenman K, Romano JD, Kennard A, Schultz A, Roos DS, Grigg ME, Carruthers VB, Coppens I. A Lipolytic Lecithin:Cholesterol Acyltransferase Secreted by Toxoplasma Facilitates Parasite Replication and Egress. The Journal of Biological Chemistry. PMID 26694607 DOI: 10.1074/Jbc.M115.671974 |
0.357 |
|
| 2015 |
Tampaki Z, Mwakubambanya RS, Goulielmaki E, Kaforou S, Kim K, Waters AP, Carruthers VB, Siden-Kiamos I, Loukeris TG, Koussis K. Ectopic expression of a Neospora caninum Kazal type inhibitor triggers developmental defects in Toxoplasma and Plasmodium. Plos One. 10: e0121379. PMID 25803874 DOI: 10.1371/Journal.Pone.0121379 |
0.397 |
|
| 2015 |
Lunghi M, Galizi R, Magini A, Carruthers VB, Di Cristina M. Expression of the glycolytic enzymes enolase and lactate dehydrogenase during the early phase of Toxoplasma differentiation is regulated by an intron retention mechanism. Molecular Microbiology. 96: 1159-75. PMID 25777509 DOI: 10.1111/mmi.12999 |
0.302 |
|
| 2015 |
Huynh MH, Liu B, Henry M, Liew L, Matthews SJ, Carruthers VB. Structural basis of Toxoplasma gondii MIC2-associated protein interaction with MIC2. The Journal of Biological Chemistry. 290: 1432-41. PMID 25411252 DOI: 10.1074/Jbc.M114.613646 |
0.363 |
|
| 2014 |
Roiko MS, Svezhova N, Carruthers VB. Acidification Activates Toxoplasma gondii Motility and Egress by Enhancing Protein Secretion and Cytolytic Activity. Plos Pathogens. 10: e1004488. PMID 25375818 DOI: 10.1371/journal.ppat.1004488 |
0.408 |
|
| 2014 |
Huynh MH, Boulanger MJ, Carruthers VB. A conserved apicomplexan microneme protein contributes to Toxoplasma gondii invasion and virulence. Infection and Immunity. 82: 4358-68. PMID 25092910 DOI: 10.1128/Iai.01877-14 |
0.493 |
|
| 2014 |
Dou Z, McGovern OL, Di Cristina M, Carruthers VB. Toxoplasma gondii ingests and digests host cytosolic proteins. Mbio. 5: e01188-14. PMID 25028423 DOI: 10.1128/Mbio.01188-14 |
0.517 |
|
| 2014 |
Liu J, Pace D, Dou Z, King TP, Guidot D, Li ZH, Carruthers VB, Moreno SN. A vacuolar-H(+) -pyrophosphatase (TgVP1) is required for microneme secretion, host cell invasion, and extracellular survival of Toxoplasma gondii. Molecular Microbiology. 93: 698-712. PMID 24975633 DOI: 10.1111/Mmi.12685 |
0.344 |
|
| 2014 |
Warring SD, Dou Z, Carruthers VB, McFadden GI, van Dooren GG. Characterization of the chloroquine resistance transporter homologue in Toxoplasma gondii. Eukaryotic Cell. 13: 1360-70. PMID 24859994 DOI: 10.1128/Ec.00027-14 |
0.341 |
|
| 2013 |
Muniz-Feliciano L, Van Grol J, Portillo JA, Liew L, Liu B, Carlin CR, Carruthers VB, Matthews S, Subauste CS. Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite. Plos Pathogens. 9: e1003809. PMID 24367261 DOI: 10.1371/Journal.Ppat.1003809 |
0.412 |
|
| 2013 |
Tomavo S, Slomianny C, Meissner M, Carruthers VB. Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion. Plos Pathogens. 9: e1003629. PMID 24204248 DOI: 10.1371/journal.ppat.1003629 |
0.496 |
|
| 2013 |
Gaji RY, Huynh MH, Carruthers VB. A novel high throughput invasion screen identifies host actin regulators required for efficient cell entry by Toxoplasma gondii. Plos One. 8: e64693. PMID 23741372 DOI: 10.1371/journal.pone.0064693 |
0.449 |
|
| 2013 |
Blackman MJ, Carruthers VB. Recent insights into apicomplexan parasite egress provide new views to a kill. Current Opinion in Microbiology. 16: 459-64. PMID 23725669 DOI: 10.1016/j.mib.2013.04.008 |
0.429 |
|
| 2013 |
Kremer K, Kamin D, Rittweger E, Wilkes J, Flammer H, Mahler S, Heng J, Tonkin CJ, Langsley G, Hell SW, Carruthers VB, Ferguson DJ, Meissner M. An overexpression screen of Toxoplasma gondii Rab-GTPases reveals distinct transport routes to the micronemes. Plos Pathogens. 9: e1003213. PMID 23505371 DOI: 10.1371/Journal.Ppat.1003213 |
0.432 |
|
| 2013 |
Roiko MS, Carruthers VB. Functional dissection of Toxoplasma gondii perforin-like protein 1 reveals a dual domain mode of membrane binding for cytolysis and parasite egress. The Journal of Biological Chemistry. 288: 8712-25. PMID 23376275 DOI: 10.1074/jbc.M113.450932 |
0.338 |
|
| 2013 |
Dou Z, Coppens I, Carruthers VB. Non-canonical maturation of two papain-family proteases in Toxoplasma gondii. The Journal of Biological Chemistry. 288: 3523-34. PMID 23250753 DOI: 10.1074/Jbc.M112.443697 |
0.351 |
|
| 2013 |
Lebrun M, Carruthers VB, Cesbron-Delauw MF. Toxoplasma Secretory Proteins and Their Roles in Cell Invasion and Intracellular Survival Toxoplasma Gondii: the Model Apicomplexan - Perspectives and Methods: Second Edition. 389-453. DOI: 10.1016/B978-0-12-396481-6.00012-X |
0.511 |
|
| 2012 |
Saouros S, Dou Z, Henry M, Marchant J, Carruthers VB, Matthews S. Microneme protein 5 regulates the activity of Toxoplasma subtilisin 1 by mimicking a subtilisin prodomain. The Journal of Biological Chemistry. 287: 36029-40. PMID 22896704 DOI: 10.1074/Jbc.M112.389825 |
0.421 |
|
| 2012 |
Sloves PJ, Delhaye S, Mouveaux T, Werkmeister E, Slomianny C, Hovasse A, Dilezitoko Alayi T, Callebaut I, Gaji RY, Schaeffer-Reiss C, Van Dorsselear A, Carruthers VB, Tomavo S. Toxoplasma sortilin-like receptor regulates protein transport and is essential for apical secretory organelle biogenesis and host infection. Cell Host & Microbe. 11: 515-27. PMID 22607804 DOI: 10.1016/j.chom.2012.03.006 |
0.471 |
|
| 2012 |
Pszenny V, Davis PH, Zhou XW, Hunter CA, Carruthers VB, Roos DS. Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice. Infection and Immunity. 80: 1156-65. PMID 22202120 DOI: 10.1128/Iai.06167-11 |
0.459 |
|
| 2011 |
Dou Z, Carruthers VB. Cathepsin proteases in Toxoplasma gondii. Advances in Experimental Medicine and Biology. 712: 49-61. PMID 21660658 DOI: 10.1007/978-1-4419-8414-2_4 |
0.404 |
|
| 2011 |
Gaji RY, Flammer HP, Carruthers VB. Forward targeting of Toxoplasma gondii proproteins to the micronemes involves conserved aliphatic amino acids. Traffic (Copenhagen, Denmark). 12: 840-53. PMID 21438967 DOI: 10.1111/j.1600-0854.2011.01192.x |
0.378 |
|
| 2011 |
Laliberté J, Carruthers VB. Toxoplasma gondii toxolysin 4 is an extensively processed putative metalloproteinase secreted from micronemes. Molecular and Biochemical Parasitology. 177: 49-56. PMID 21277910 DOI: 10.1016/j.molbiopara.2011.01.009 |
0.415 |
|
| 2011 |
Gaji RY, Behnke MS, Lehmann MM, White MW, Carruthers VB. Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression. Molecular Microbiology. 79: 192-204. PMID 21166903 DOI: 10.1111/j.1365-2958.2010.07441.x |
0.437 |
|
| 2010 |
Beck JR, Rodriguez-Fernandez IA, de Leon JC, Huynh MH, Carruthers VB, Morrissette NS, Bradley PJ. A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division. Plos Pathogens. 6: e1001094. PMID 20844581 DOI: 10.1371/Journal.Ppat.1001094 |
0.38 |
|
| 2010 |
Lagal V, Binder EM, Huynh MH, Kafsack BF, Harris PK, Diez R, Chen D, Cole RN, Carruthers VB, Kim K. Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites. Cellular Microbiology. 12: 1792-808. PMID 20678172 DOI: 10.1111/J.1462-5822.2010.01509.X |
0.787 |
|
| 2010 |
Kafsack BF, Carruthers VB. Apicomplexan perforin-like proteins. Communicative & Integrative Biology. 3: 18-23. PMID 20539776 DOI: 10.4161/cib.3.1.10076 |
0.768 |
|
| 2010 |
Parussini F, Coppens I, Shah PP, Diamond SL, Carruthers VB. Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii. Molecular Microbiology. 76: 1340-57. PMID 20444089 DOI: 10.1111/J.1365-2958.2010.07181.X |
0.501 |
|
| 2009 |
Roiko MS, Carruthers VB. New roles for perforins and proteases in apicomplexan egress. Cellular Microbiology. 11: 1444-52. PMID 19614666 DOI: 10.1111/j.1462-5822.2009.01357.x |
0.476 |
|
| 2009 |
Larson ET, Parussini F, Huynh MH, Giebel JD, Kelley AM, Zhang L, Bogyo M, Merritt EA, Carruthers VB. Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl. The Journal of Biological Chemistry. 284: 26839-50. PMID 19596863 DOI: 10.1074/Jbc.M109.003780 |
0.47 |
|
| 2009 |
Breinich MS, Ferguson DJ, Foth BJ, van Dooren GG, Lebrun M, Quon DV, Striepen B, Bradley PJ, Frischknecht F, Carruthers VB, Meissner M. A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii. Current Biology : Cb. 19: 277-86. PMID 19217293 DOI: 10.1016/j.cub.2009.01.039 |
0.373 |
|
| 2009 |
Kafsack BF, Pena JD, Coppens I, Ravindran S, Boothroyd JC, Carruthers VB. Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Science (New York, N.Y.). 323: 530-3. PMID 19095897 DOI: 10.1126/Science.1165740 |
0.813 |
|
| 2009 |
Kafsack BF, Carruthers VB, Pineda FJ. Erratum to “Kinetic modeling of Toxoplasma gondii invasion” [J. Theor. Biol. 249 (2007) 817–825] Journal of Theoretical Biology. 260: 598. DOI: 10.1016/j.jtbi.2009.05.034 |
0.672 |
|
| 2008 |
Carruthers VB, Tomley FM. Microneme proteins in apicomplexans. Sub-Cellular Biochemistry. 47: 33-45. PMID 18512339 |
0.428 |
|
| 2008 |
Laliberté J, Carruthers VB. Host cell manipulation by the human pathogen Toxoplasma gondii Cellular and Molecular Life Sciences. 65: 1900-1915. PMID 18327664 DOI: 10.1007/s00018-008-7556-x |
0.446 |
|
| 2008 |
Hager KM, Carruthers VB. MARveling at parasite invasion. Trends in Parasitology. 24: 51-4. PMID 18203663 DOI: 10.1016/J.Pt.2007.10.008 |
0.425 |
|
| 2008 |
Brydges SD, Harper JM, Parussini F, Coppens I, Carruthers VB. A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 100: 253-64. PMID 17995454 DOI: 10.1042/Bc20070076 |
0.785 |
|
| 2007 |
Kafsack BF, Carruthers VB, Pineda FJ. Kinetic modeling of Toxoplasma gondii invasion. Journal of Theoretical Biology. 249: 817-25. PMID 17942124 DOI: 10.1016/j.jtbi.2007.09.008 |
0.779 |
|
| 2007 |
Carruthers VB, Suzuki Y. Effects of Toxoplasma gondii infection on the brain. Schizophrenia Bulletin. 33: 745-51. PMID 17322557 DOI: 10.1093/schbul/sbm008 |
0.318 |
|
| 2007 |
Teo CF, Zhou XW, Bogyo M, Carruthers VB. Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion. Antimicrobial Agents and Chemotherapy. 51: 679-88. PMID 17145790 DOI: 10.1128/Aac.01059-06 |
0.474 |
|
| 2007 |
Carruthers V, Boothroyd JC. Pulling together: an integrated model of Toxoplasma cell invasion. Current Opinion in Microbiology. 10: 83-9. PMID 16837236 DOI: 10.1016/J.Mib.2006.06.017 |
0.648 |
|
| 2006 |
Brydges SD, Zhou XW, Huynh MH, Harper JM, Mital J, Adjogble KD, Däubener W, Ward GE, Carruthers VB. Targeted deletion of MIC5 enhances trimming proteolysis of Toxoplasma invasion proteins. Eukaryotic Cell. 5: 2174-83. PMID 16980407 DOI: 10.1128/Ec.00163-06 |
0.798 |
|
| 2006 |
Huynh MH, Carruthers VB. Toxoplasma MIC2 is a major determinant of invasion and virulence. Plos Pathogens. 2: e84. PMID 16933991 DOI: 10.1371/journal.ppat.0020084 |
0.437 |
|
| 2006 |
Starnes GL, Jewett TJ, Carruthers VB, Sibley LD. Two separate, conserved acidic amino acid domains within the Toxoplasma gondii MIC2 cytoplasmic tail are required for parasite survival. The Journal of Biological Chemistry. 281: 30745-54. PMID 16923803 DOI: 10.1074/jbc.M606523200 |
0.578 |
|
| 2006 |
Harper JM, Huynh MH, Coppens I, Parussini F, Moreno S, Carruthers VB. A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complex. Molecular Biology of the Cell. 17: 4551-63. PMID 16914527 DOI: 10.1091/mbc.E06-01-0064 |
0.432 |
|
| 2006 |
Carruthers VB. Proteolysis and Toxoplasma invasion. International Journal For Parasitology. 36: 595-600. PMID 16600244 DOI: 10.1016/j.ijpara.2006.02.008 |
0.401 |
|
| 2006 |
Huynh MH, Harper JM, Carruthers VB. Preparing for an invasion: charting the pathway of adhesion proteins to Toxoplasma micronemes. Parasitology Research. 98: 389-95. PMID 16385407 DOI: 10.1007/s00436-005-0062-2 |
0.399 |
|
| 2005 |
Howell SA, Hackett F, Jongco AM, Withers-Martinez C, Kim K, Carruthers VB, Blackman MJ. Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens. Molecular Microbiology. 57: 1342-56. PMID 16102004 DOI: 10.1111/J.1365-2958.2005.04772.X |
0.466 |
|
| 2005 |
Zhou XW, Kafsack BF, Cole RN, Beckett P, Shen RF, Carruthers VB. The opportunistic pathogen Toxoplasma gondii deploys a diverse legion of invasion and survival proteins. The Journal of Biological Chemistry. 280: 34233-44. PMID 16002397 DOI: 10.1074/jbc.M504160200 |
0.785 |
|
| 2005 |
Carruthers VB, Blackman MJ. A new release on life: emerging concepts in proteolysis and parasite invasion. Molecular Microbiology. 55: 1617-30. PMID 15752188 DOI: 10.1111/j.1365-2958.2005.04483.x |
0.421 |
|
| 2004 |
Kafsack BF, Beckers C, Carruthers VB. Synchronous invasion of host cells by Toxoplasma gondii. Molecular and Biochemical Parasitology. 136: 309-11. PMID 15478810 DOI: 10.1016/j.molbiopara.2004.04.004 |
0.767 |
|
| 2004 |
Harper JM, Zhou XW, Pszenny V, Kafsack BF, Carruthers VB. The novel coccidian micronemal protein MIC11 undergoes proteolytic maturation by sequential cleavage to remove an internal propeptide. International Journal For Parasitology. 34: 1047-58. PMID 15313131 DOI: 10.1016/j.ijpara.2004.05.006 |
0.796 |
|
| 2004 |
Huynh MH, Opitz C, Kwok LY, Tomley FM, Carruthers VB, Soldati D. Trans-genera reconstitution and complementation of an adhesion complex in Toxoplasma gondii. Cellular Microbiology. 6: 771-82. PMID 15236644 DOI: 10.1111/j.1462-5822.2004.00403.x |
0.456 |
|
| 2004 |
Morris MT, Cheng WC, Zhou XW, Brydges SD, Carruthers VB. Neospora caninum expresses an unusual single-domain Kazal protease inhibitor that is discharged into the parasitophorous vacuole. International Journal For Parasitology. 34: 693-701. PMID 15111091 DOI: 10.1016/J.Ijpara.2004.01.004 |
0.747 |
|
| 2004 |
Harper JM, Hoff EF, Carruthers VB. Multimerization of the Toxoplasma gondii MIC2 integrin-like A-domain is required for binding to heparin and human cells. Molecular and Biochemical Parasitology. 134: 201-12. PMID 15003840 DOI: 10.1016/j.molbiopara.2003.12.001 |
0.346 |
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| 2004 |
Zhou XW, Blackman MJ, Howell SA, Carruthers VB. Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex. Molecular & Cellular Proteomics : McP. 3: 565-76. PMID 14982962 DOI: 10.1074/mcp.M300123-MCP200 |
0.336 |
|
| 2003 |
Brydges SD, Carruthers VB. Mutation of an unusual mitochondrial targeting sequence of SODB2 produces multiple targeting fates in Toxoplasma gondii. Journal of Cell Science. 116: 4675-85. PMID 14576360 DOI: 10.1242/Jcs.00750 |
0.728 |
|
| 2003 |
Hoane JS, Carruthers VB, Striepen B, Morrison DP, Entzeroth R, Howe DK. Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development. International Journal For Parasitology. 33: 671-9. PMID 12814647 DOI: 10.1016/S0020-7519(03)00031-6 |
0.431 |
|
| 2003 |
Huynh MH, Rabenau KE, Harper JM, Beatty WL, Sibley LD, Carruthers VB. Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex. The Embo Journal. 22: 2082-90. PMID 12727875 DOI: 10.1093/emboj/cdg217 |
0.668 |
|
| 2002 |
Morris MT, Coppin A, Tomavo S, Carruthers VB. Functional analysis of Toxoplasma gondii protease inhibitor 1. The Journal of Biological Chemistry. 277: 45259-66. PMID 12228242 DOI: 10.1074/jbc.M205517200 |
0.31 |
|
| 2002 |
Hoff EF, Carruthers VB. Is Toxoplasma egress the first step in invasion? Trends in Parasitology. 18: 251-5. PMID 12036737 DOI: 10.1016/S1471-4922(02)02240-7 |
0.393 |
|
| 2002 |
Carruthers VB. Host cell invasion by the opportunistic pathogen Toxoplasma gondii. Acta Tropica. 81: 111-22. PMID 11801218 DOI: 10.1016/S0001-706X(01)00201-7 |
0.481 |
|
| 2001 |
Miller SA, Binder EM, Blackman MJ, Carruthers VB, Kim K. A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii. The Journal of Biological Chemistry. 276: 45341-8. PMID 11564738 DOI: 10.1074/Jbc.M106665200 |
0.467 |
|
| 2001 |
Rabenau KE, Sohrabi A, Tripathy A, Reitter C, Ajioka JW, Tomley FM, Carruthers VB. TgM2AP participates in toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2 Molecular Microbiology. 41: 537-547. PMID 11532123 DOI: 10.1046/j.1365-2958.2001.02513.x |
0.537 |
|
| 2001 |
Hoff EF, Cook SH, Sherman GD, Harper JM, Ferguson DJ, Dubremetz JF, Carruthers VB. Toxoplasma gondii: molecular cloning and characterization of a novel 18-kDa secretory antigen, TgMIC10. Experimental Parasitology. 97: 77-88. PMID 11281704 DOI: 10.1006/expr.2000.4585 |
0.409 |
|
| 2001 |
Brecht S, Carruthers VB, Ferguson DJ, Giddings OK, Wang G, Jakle U, Harper JM, Sibley LD, Soldati D. The toxoplasma micronemal protein MIC4 is an adhesin composed of six conserved apple domains. The Journal of Biological Chemistry. 276: 4119-27. PMID 11053441 DOI: 10.1074/jbc.M008294200 |
0.636 |
|
| 2000 |
Brydges SD, Sherman GD, Nockemann S, Loyens A, Däubener W, Dubremetz JF, Carruthers VB. Molecular characterization of TgMIC5, a proteolytically processed antigen secreted from the micronemes of Toxoplasma gondii. Molecular and Biochemical Parasitology. 111: 51-66. PMID 11087916 DOI: 10.1016/S0166-6851(00)00296-6 |
0.795 |
|
| 2000 |
Donahue CG, Carruthers VB, Gilk SD, Ward GE. The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels. Molecular and Biochemical Parasitology. 111: 15-30. PMID 11087913 DOI: 10.1016/S0166-6851(00)00289-9 |
0.338 |
|
| 2000 |
Carruthers VB, Håkansson S, Giddings OK, Sibley LD. Toxoplasma gondii uses sulfated proteoglycans for substrate and host cell attachment. Infection and Immunity. 68: 4005-11. PMID 10858215 DOI: 10.1128/IAI.68.7.4005-4011.2000 |
0.652 |
|
| 2000 |
Carruthers VB, Sherman GD, Sibley LD. The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteases. The Journal of Biological Chemistry. 275: 14346-53. PMID 10799515 DOI: 10.1074/jbc.275.19.14346 |
0.62 |
|
| 1999 |
Carruthers VB. Armed and dangerous: Toxoplasma gondii uses an arsenal of secretory proteins to infect host cells Parasitology International. 48: 1-10. PMID 11269320 DOI: 10.1016/S1383-5769(98)00042-7 |
0.517 |
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| 1999 |
Carruthers VB, Giddings OK, Sibley LD. Secretion of micronemal proteins is associated with toxoplasma invasion of host cells. Cellular Microbiology. 1: 225-35. PMID 11207555 |
0.68 |
|
| 1999 |
Carruthers VB, Moreno SNJ, Sibley LD. Ethanol and acetaldehyde elevate intracellular [Ca2+] and stimulate microneme discharge in Toxoplasma gondii Biochemical Journal. 342: 379-386. PMID 10455025 DOI: 10.1042/0264-6021:3420379 |
0.513 |
|
| 1999 |
Carruthers VB, Sibley LD. Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondii Molecular Microbiology. 31: 421-428. PMID 10027960 DOI: 10.1046/j.1365-2958.1999.01174.x |
0.558 |
|
| 1999 |
Sibley LD, Carruthers VB, Mordue D, Mercier C, Håkansson S. Active cell invasion by Toxoplasma gondii leads to avoidance of phagocytic processing Advances in Cellular and Molecular Biology of Membranes and Organelles. 6: 263-280. DOI: 10.1016/S1874-5172(99)80015-7 |
0.674 |
|
| 1998 |
Sibley LD, Håkansson S, Carruthers VB. Gliding motility: An efficient mechanism for cell penetration Current Biology. 8. PMID 9427622 |
0.607 |
|
| 1997 |
Dobrowolski JM, Carruthers VB, Sibley LD. Participation of myosin in gliding motility and host cell invasion by Toxoplasma gondii Molecular Microbiology. 26: 163-173. PMID 9383198 |
0.643 |
|
| 1997 |
Carruthers VB, Sibley LD. Sequential protein secretion front three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts European Journal of Cell Biology. 73: 114-123. PMID 9208224 |
0.5 |
|
| 1997 |
Wan KL, Carruthers VB, Sibley LD, Ajioka JW. Molecular characterisation of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2 Molecular and Biochemical Parasitology. 84: 203-214. PMID 9084040 DOI: 10.1016/S0166-6851(96)02796-X |
0.555 |
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