David T. Denhardt - Publications

Affiliations: 
1964-1970 Harvard University, Cambridge, MA, United States 
 1970-1980 McGill University, Montreal, QC, Canada 
 1980-1988 University of Western Ontario, London, Ontario, Canada 
 1988- Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
http://lifesci.dls.rutgers.edu/~denhardt/DTD_CV.htm

265 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Denhardt DT. Effect of stress on human biology: Epigenetics, adaptation, inheritance, and social significance. Journal of Cellular Physiology. PMID 28158904 DOI: 10.1002/Jcp.25837  0.331
2015 Martín-Alonso M, García-Redondo AB, Guo D, Camafeita E, Martínez F, Alfranca A, Méndez-Barbero N, Pollán Á, Sánchez-Camacho C, Denhardt DT, Seiki M, Vázquez J, Salaices M, Redondo JM, Milewicz D, et al. Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. Circulation Research. 117: e13-26. PMID 25963716 DOI: 10.1161/Circresaha.117.305108  0.37
2015 Ezura Y, Nagata J, Nagao M, Hemmi H, Hayata T, Rittling S, Denhardt DT, Noda M. Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells. Journal of Bone and Mineral Metabolism. 33: 48-54. PMID 24831120 DOI: 10.1007/S00774-014-0568-8  0.448
2014 Chen Q, Shou P, Zhang L, Xu C, Zheng C, Han Y, Li W, Huang Y, Zhang X, Shao C, Roberts AI, Rabson AB, Ren G, Zhang Y, Wang Y, ... Denhardt DT, et al. An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells. Stem Cells (Dayton, Ohio). 32: 327-37. PMID 24123709 DOI: 10.1002/Stem.1567  0.424
2013 Schunke KJ, Coyle L, Merrill GF, Denhardt DT. Acetaminophen attenuates doxorubicin-induced cardiac fibrosis via osteopontin and GATA4 regulation: reduction of oxidant levels. Journal of Cellular Physiology. 228: 2006-14. PMID 23526585 DOI: 10.1002/Jcp.24367  0.409
2012 Yumoto K, Nifuji A, Rittling SR, Tsuchiya Y, Kon S, Uede T, Denhardt DT, Hemmi H, Notomi T, Hayata T, Ezura Y, Nakamoto T, Noda M. Osteopontin Deficiency Suppresses Tumor Necrosis Factor-α-Induced Apoptosis in Chondrocytes. Cartilage. 3: 79-85. PMID 26069621 DOI: 10.1177/1947603511421502  0.369
2012 Diao H, Liu X, Wu Z, Kang L, Cui G, Morimoto J, Denhardt DT, Rittling S, Iwakura Y, Uede T, Li L. Osteopontin regulates interleukin-17 production in hepatitis. Cytokine. 60: 129-37. PMID 22818182 DOI: 10.1016/J.Cyto.2012.06.287  0.352
2011 Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, ... ... Denhardt DT, et al. Sympathetic control of bone mass regulated by osteopontin. Proceedings of the National Academy of Sciences of the United States of America. 108: 17767-72. PMID 21990347 DOI: 10.1073/Pnas.1109402108  0.607
2011 Irita J, Okura T, Jotoku M, Nagao T, Enomoto D, Kurata M, Desilva VR, Miyoshi K, Matsui Y, Uede T, Denhardt DT, Rittiling SR, Higaki J. Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney. American Journal of Physiology. Renal Physiology. 301: F833-44. PMID 21734100 DOI: 10.1152/Ajprenal.00557.2010  0.399
2011 Morishita M, Ono N, Miyai K, Nakagawa T, Hanyu R, Nagao M, Kamolratanakul P, Notomi T, Rittling SR, Denhardt DT, Kronenberg HM, Ezura Y, Hayata T, Nakamoto T, Noda M. Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology. Tissue & Cell. 43: 196-200. PMID 21511320 DOI: 10.1016/J.Tice.2011.02.003  0.442
2011 Baliga SS, Merrill GF, Shinohara ML, Denhardt DT. Osteopontin expression during early cerebral ischemia-reperfusion in rats: enhanced expression in the right cortex is suppressed by acetaminophen. Plos One. 6: e14568. PMID 21283687 DOI: 10.1371/Journal.Pone.0014568  0.377
2010 Lazar M, Sullivan J, Chipitsyna G, Gong Q, Ng CY, Salem AF, Aziz T, Witkiewicz A, Denhardt DT, Yeo CJ, Arafat HA. Involvement of osteopontin in the matrix-degrading and proangiogenic changes mediated by nicotine in pancreatic cancer cells. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 14: 1566-77. PMID 20824368 DOI: 10.1007/S11605-010-1338-0  0.387
2010 Lazar M, Sullivan J, Chipitsyna G, Aziz T, Salem AF, Gong Q, Witkiewicz A, Denhardt DT, Yeo CJ, Arafat HA. Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin. Surgery. 148: 298-309. PMID 20579680 DOI: 10.1016/J.Surg.2010.05.002  0.408
2010 Haders DJ, Kazanecki CC, Denhardt DT, Riman RE. Crystallographically engineered, hydrothermally crystallized hydroxyapatite films: an in vitro study of bioactivity. Journal of Materials Science. Materials in Medicine. 21: 1531-42. PMID 20232236 DOI: 10.1007/S10856-010-4031-7  0.756
2010 Shimizu S, Okuda N, Kato N, Rittling SR, Okawa A, Shinomiya K, Muneta T, Denhardt DT, Noda M, Tsuji K, Asou Y. Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages. Arthritis and Rheumatism. 62: 1329-37. PMID 20155835 DOI: 10.1002/Art.27400  0.408
2010 Fujita N, Fujita S, Okada Y, Fujita K, Kitano A, Yamanaka O, Miyamoto T, Kon S, Uede T, Rittling SR, Denhardt DT, Saika S. Impaired angiogenic response in the corneas of mice lacking osteopontin. Investigative Ophthalmology & Visual Science. 51: 790-4. PMID 19741245 DOI: 10.1167/Iovs.09-3420  0.396
2010 Iwabuchi K, Iwata D, Kitamura M, Kitaichi N, Kon S, Kitamei H, Namba K, Yoshida K, Ishida S, Ohno S, Rittling SR, Denhardt DT, Uede T, Onoe K, Horai R, et al. Immunological diseases of the eye (WS-099) Chairpersons: Koh-hei Sonoda, Nobuyuki Ohguro International Immunology. 22. DOI: 10.1093/Intimm/Dxq358  0.291
2009 Matsui Y, Iwasaki N, Kon S, Takahashi D, Morimoto J, Matsui Y, Denhardt DT, Rittling S, Minami A, Uede T. Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice. Arthritis and Rheumatism. 60: 2362-71. PMID 19644889 DOI: 10.1002/Art.24705  0.4
2009 Sullivan J, Blair L, Alnajar A, Aziz T, Ng CY, Chipitsyna G, Gong Q, Witkiewicz A, Weber GF, Denhardt DT, Yeo CJ, Arafat HA. Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma. Surgery. 146: 232-40. PMID 19628079 DOI: 10.1016/J.Surg.2009.03.036  0.392
2009 Grassinger J, Haylock DN, Storan MJ, Haines GO, Williams B, Whitty GA, Vinson AR, Be CL, Li S, Sørensen ES, Tam PP, Denhardt DT, Sheppard D, Choong PF, Nilsson SK. Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. Blood. 114: 49-59. PMID 19417209 DOI: 10.1182/Blood-2009-01-197988  0.398
2009 Chipitsyna G, Gong Q, Anandanadesan R, Alnajar A, Batra SK, Wittel UA, Cullen DM, Akhter MP, Denhardt DT, Yeo CJ, Arafat HA. Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells. International Journal of Cancer. 125: 276-85. PMID 19358273 DOI: 10.1002/Ijc.24388  0.383
2009 Maeno Y, Shinzato M, Nagashima S, Rittling SR, Denhardt DT, Uede T, Taniguchi K. Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus. Viral Immunology. 22: 139-44. PMID 19327001 DOI: 10.1089/Vim.2008.0054  0.401
2009 Wang KX, Shi YF, Ron Y, Kazanecki CC, Denhardt DT. Plasma osteopontin modulates chronic restraint stress-induced thymus atrophy by regulating stress hormones: inhibition by an anti-osteopontin monoclonal antibody. Journal of Immunology (Baltimore, Md. : 1950). 182: 2485-91. PMID 19201904 DOI: 10.4049/Jimmunol.0803023  0.761
2008 Wang KX, Denhardt DT. Osteopontin: role in immune regulation and stress responses. Cytokine & Growth Factor Reviews. 19: 333-45. PMID 18952487 DOI: 10.1016/j.cytogfr.2008.08.001  0.557
2008 Diao H, Iwabuchi K, Li L, Onoe K, Van Kaer L, Kon S, Saito Y, Morimoto J, Denhardt DT, Rittling S, Uede T. Osteopontin regulates development and function of invariant natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 15884-9. PMID 18836077 DOI: 10.1073/Pnas.0806089105  0.45
2008 Sato I, Yamamoto N, Rittling SR, Denhardt DT, Hino M, Morimoro J, Sakai F, Fujie A, Uede T. Osteopontin is dispensable for protection against high load systemic fungal infection. International Immunopharmacology. 8: 1441-8. PMID 18590834 DOI: 10.1016/J.Intimp.2008.06.001  0.385
2008 Borges K, Gearing M, Rittling S, Sorensen ES, Kotloski R, Denhardt DT, Dingledine R. Characterization of osteopontin expression and function after status epilepticus. Epilepsia. 49: 1675-85. PMID 18522644 DOI: 10.1111/J.1528-1167.2008.01613.X  0.402
2008 Ono N, Nakashima K, Rittling SR, Schipani E, Hayata T, Soma K, Denhardt DT, Kronenberg HM, Ezura Y, Noda M. Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts Journal of Biological Chemistry. 283: 19400-19409. PMID 18417476 DOI: 10.1074/Jbc.M800005200  0.451
2008 Miyazaki K, Okada Y, Yamanaka O, Kitano A, Ikeda K, Kon S, Uede T, Rittling SR, Denhardt DT, Kao WW, Saika S. Corneal wound healing in an osteopontin-deficient mouse. Investigative Ophthalmology & Visual Science. 49: 1367-75. PMID 18385052 DOI: 10.1167/Iovs.07-1007  0.387
2008 Chung CJ, Soma K, Rittling SR, Denhardt DT, Hayata T, Nakashima K, Ezura Y, Noda M. OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application. Journal of Cellular Physiology. 214: 614-20. PMID 17894420 DOI: 10.1002/Jcp.21250  0.425
2007 Kazanecki CC, Uzwiak DJ, Denhardt DT. Control of osteopontin signaling and function by post-translational phosphorylation and protein folding. Journal of Cellular Biochemistry. 102: 912-24. PMID 17910028 DOI: 10.1002/Jcb.21558  0.788
2007 Kazanecki CC, Kowalski AJ, Ding T, Rittling SR, Denhardt DT. Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to post-translational modifications. Journal of Cellular Biochemistry. 102: 925-35. PMID 17786932 DOI: 10.1002/Jcb.21487  0.757
2007 Wang KX, Shi Y, Denhardt DT. Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production. Proceedings of the National Academy of Sciences of the United States of America. 104: 14777-82. PMID 17785423 DOI: 10.1073/Pnas.0703236104  0.594
2007 Christensen B, Kazanecki CC, Petersen TE, Rittling SR, Denhardt DT, Sørensen ES. Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties. The Journal of Biological Chemistry. 282: 19463-72. PMID 17500062 DOI: 10.1074/Jbc.M703055200  0.784
2007 Kitamura M, Iwabuchi K, Kitaichi N, Kon S, Kitamei H, Namba K, Yoshida K, Denhardt DT, Rittling SR, Ohno S, Uede T, Onoé K. Osteopontin aggravates experimental autoimmune uveoretinitis in mice. Journal of Immunology (Baltimore, Md. : 1950). 178: 6567-72. PMID 17475887 DOI: 10.4049/Jimmunol.178.10.6567  0.425
2007 Ishijima M, Tsuji K, Rittling SR, Yamashita T, Kurosawa H, Denhardt DT, Nifuji A, Ezura Y, Noda M. Osteopontin is required for mechanical stress-dependent signals to bone marrow cells. The Journal of Endocrinology. 193: 235-43. PMID 17470514 DOI: 10.1677/Joe.1.06704  0.445
2007 Kato N, Kitahara K, Rittling SR, Nakashima K, Denhardt DT, Kurosawa H, Ezura Y, Noda M. Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone. The Journal of Endocrinology. 193: 171-82. PMID 17400814 DOI: 10.1677/Joe.1.06917  0.413
2007 Hashimoto M, Sun D, Rittling SR, Denhardt DT, Young W. Osteopontin-deficient mice exhibit less inflammation, greater tissue damage, and impaired locomotor recovery from spinal cord injury compared with wild-type controls. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3603-11. PMID 17392476 DOI: 10.1523/Jneurosci.4805-06.2007  0.365
2007 Kavukcuoglu NB, Denhardt DT, Guzelsu N, Mann AB. Osteopontin deficiency and aging on nanomechanics of mouse bone. Journal of Biomedical Materials Research. Part A. 83: 136-44. PMID 17390367 DOI: 10.1002/Jbm.A.31081  0.392
2007 Hayashi C, Rittling S, Hayata T, Amagasa T, Denhardt D, Ezura Y, Nakashima K, Noda M. Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration Journal of Cellular Biochemistry. 101: 979-986. PMID 17390343 DOI: 10.1002/Jcb.21298  0.447
2007 Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Current Alzheimer Research. 4: 67-72. PMID 17316167 DOI: 10.2174/156720507779939869  0.692
2007 Marsh BC, Kerr NC, Isles N, Denhardt DT, Wynick D. Osteopontin expression and function within the dorsal root ganglion. Neuroreport. 18: 153-7. PMID 17301681 DOI: 10.1097/Wnr.0B013E328010D4Fa  0.39
2007 Saika S, Shirai K, Yamanaka O, Miyazaki K, Okada Y, Kitano A, Flanders KC, Kon S, Uede T, Kao WW, Rittling SR, Denhardt DT, Ohnishi Y. Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 130-8. PMID 17211411 DOI: 10.1038/Labinvest.3700508  0.448
2007 Mori N, Majima T, Iwasaki N, Kon S, Miyakawa K, Kimura C, Tanaka K, Denhardt DT, Rittling S, Minami A, Uede T. The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation. Matrix Biology : Journal of the International Society For Matrix Biology. 26: 42-53. PMID 17055235 DOI: 10.1016/J.Matbio.2006.09.002  0.407
2006 Ishijima M, Ezura Y, Tsuji K, Rittling SR, Kurosawa H, Denhardt DT, Emi M, Nifuji A, Noda M. Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss. Experimental Cell Research. 312: 3075-83. PMID 16889770 DOI: 10.1016/J.Yexcr.2006.06.003  0.453
2006 Da Silva AP, Pollett A, Rittling SR, Denhardt DT, Sodek J, Zohar R. Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death. Journal of Cellular Physiology. 208: 629-39. PMID 16741956 DOI: 10.1002/Jcp.20701  0.413
2006 Lai CF, Seshadri V, Huang K, Shao JS, Cai J, Vattikuti R, Schumacher A, Loewy AP, Denhardt DT, Rittling SR, Towler DA. An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells. Circulation Research. 98: 1479-89. PMID 16709900 DOI: 10.1161/01.Res.0000227550.00426.60  0.389
2006 Schroeter M, Zickler P, Denhardt DT, Hartung HP, Jander S. Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. Brain : a Journal of Neurology. 129: 1426-37. PMID 16636021 DOI: 10.1093/Brain/Awl094  0.39
2006 Maeno Y, Nakazawa S, Yamamoto N, Shinzato M, Nagashima S, Tanaka K, Sasaki J, Rittling SR, Denhardt DT, Uede T, Taniguchi K. Osteopontin participates in Th1-mediated host resistance against nonlethal malaria parasite Plasmodium chabaudi chabaudi infection in mice. Infection and Immunity. 74: 2423-7. PMID 16552072 DOI: 10.1128/Iai.74.4.2423-2427.2006  0.375
2006 Koyama Y, Rittling SR, Tsuji K, Hino K, Salincarnboriboon R, Yano T, Taketani Y, Nifuji A, Denhardt DT, Noda M. Osteopontin deficiency suppresses high phosphate load-induced bone loss via specific modulation of osteoclasts. Endocrinology. 147: 3040-9. PMID 16513836 DOI: 10.1210/En.2005-0671  0.411
2005 Khan SA, Cook AC, Kappil M, Günthert U, Chambers AF, Tuck AB, Denhardt DT. Enhanced cell surface CD44 variant (v6, v9) expression by osteopontin in breast cancer epithelial cells facilitates tumor cell migration: novel post-transcriptional, post-translational regulation. Clinical & Experimental Metastasis. 22: 663-73. PMID 16691370 DOI: 10.1007/S10585-006-9007-0  0.58
2005 Porter JF, Sharma S, Wilson DL, Kappil MA, Hart RP, Denhardt DT. Tissue inhibitor of metalloproteinases-1 stimulates gene expression in MDA-MB-435 human breast cancer cells by means of its ability to inhibit metalloproteinases. Breast Cancer Research and Treatment. 94: 185-93. PMID 16142437 DOI: 10.1007/S10549-005-7728-4  0.452
2005 Vernon HJ, Osborne C, Tzortzaki EG, Yang M, Chen J, Rittling SR, Denhardt DT, Buyske S, Bledsoe SB, Evan AP, Fairbanks L, Simmonds HA, Tischfield JA, Sahota A. Aprt/Opn double knockout mice: osteopontin is a modifier of kidney stone disease severity. Kidney International. 68: 938-47. PMID 16105024 DOI: 10.1111/J.1523-1755.2005.00487.X  0.384
2005 Zhu Y, Denhardt DT, Cao H, Sutphin PD, Koong AC, Giaccia AJ, Le QT. Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene. 24: 6555-63. PMID 16007184 DOI: 10.1038/Sj.Onc.1208800  0.445
2005 Kondo H, Nifuji A, Takeda S, Ezura Y, Rittling SR, Denhardt DT, Nakashima K, Karsenty G, Noda M. Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. The Journal of Biological Chemistry. 280: 30192-200. PMID 15961387 DOI: 10.1074/Jbc.M504179200  0.415
2005 Denhardt D. Osteopontin expression correlates with melanoma invasion. The Journal of Investigative Dermatology. 124: xvi-xviii. PMID 15854023 DOI: 10.1111/j.0022-202X.2005.23708.x  0.24
2005 Nilsson SK, Johnston HM, Whitty GA, Williams B, Webb RJ, Denhardt DT, Bertoncello I, Bendall LJ, Simmons PJ, Haylock DN. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood. 106: 1232-9. PMID 15845900 DOI: 10.1182/Blood-2004-11-4422  0.454
2005 Contractor T, Babiarz B, Kowalski AJ, Rittling SR, Sørensen ES, Denhardt DT. Osteoclasts resorb protein-free mineral (Osteologic discs) efficiently in the absence of osteopontin. In Vivo (Athens, Greece). 19: 335-41. PMID 15796195  0.677
2005 Rollo EE, Hempson SJ, Bansal A, Tsao E, Habib I, Rittling SR, Denhardt DT, Mackow ER, Shaw RD. The cytokine osteopontin modulates the severity of rotavirus diarrhea. Journal of Virology. 79: 3509-16. PMID 15731245 DOI: 10.1128/Jvi.79.6.3509-3516.2005  0.436
2005 Kavukcuoglu B, West C, Denhardt DT, Mann AB. Effects of osteopontin deficiency and aging on nanomechanics of mouse bone Materials Research Society Symposium Proceedings. 844: 27-32. DOI: 10.1557/Proc-841-R3.5/Y3.5  0.396
2005 Jander S, Schroeter M, Denhardt DT. Osteopontin mediates neuroprotection via inhibition of inducible nitric oxide synthase Journal of Cerebral Blood Flow and Metabolism. 25. DOI: 10.1038/Sj.Jcbfm.9591524.0101  0.391
2004 Diao H, Kon S, Iwabuchi K, Kimura C, Morimoto J, Ito D, Segawa T, Maeda M, Hamuro J, Nakayama T, Taniguchi M, Yagita H, Kaer LV, Onóe K, Denhardt D, et al. Osteopontin as a Mediator of NKT Cell Function in T Cell-Mediated Liver Diseases Immunity. 21: 539-550. PMID 15485631 DOI: 10.1016/J.Immuni.2004.08.012  0.417
2004 Ohyama Y, Nemoto H, Rittling S, Tsuji K, Amagasa T, Denhardt DT, Nifuji A, Noda M. Osteopontin-deficiency suppresses growth of B16 melanoma cells implanted in bone and osteoclastogenesis in co-cultures. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 1706-11. PMID 15355566 DOI: 10.1359/Jbmr.2004.19.10.1706  0.392
2004 Matsui Y, Jia N, Okamoto H, Kon S, Onozuka H, Akino M, Liu L, Morimoto J, Rittling SR, Denhardt D, Kitabatake A, Uede T. Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy. Hypertension. 43: 1195-201. PMID 15123578 DOI: 10.1161/01.Hyp.0000128621.68160.Dd  0.351
2004 Denhardt DT. The Third International Conference on Osteopontin and Related Proteins, San Antonio, Texas, May 10-12, 2002 Calcified Tissue International. 74: 213-219. PMID 15035246 DOI: 10.1007/S00223-003-0057-X  0.432
2004 Morimoto J, Inobe M, Kimura C, Kon S, Diao H, Aoki M, Miyazaki T, Denhardt DT, Rittling S, Uede T. Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms. International Immunology. 16: 477-88. PMID 14978021 DOI: 10.1093/Intimm/Dxh044  0.371
2004 Porter JF, Shen S, Denhardt DT. Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase. British Journal of Cancer. 90: 463-70. PMID 14735194 DOI: 10.1038/Sj.Bjc.6601533  0.433
2004 Weintraub AS, Lin X, Itskovich VV, Aguinaldo JG, Chaplin WF, Denhardt DT, Fayad ZA. Prenatal detection of embryo resorption in osteopontin-deficient mice using serial noninvasive magnetic resonance microscopy. Pediatric Research. 55: 419-24. PMID 14711899 DOI: 10.1203/01.Pdr.0000112034.98387.B2  0.363
2004 Zhu B, Suzuki K, Goldberg HA, Rittling SR, Denhardt DT, McCulloch CA, Sodek J. Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin. Journal of Cellular Physiology. 198: 155-67. PMID 14584055 DOI: 10.1002/Jcp.10394  0.408
2003 Wong YF, Selvanayagam ZE, Wei N, Porter J, Vittal R, Hu R, Lin Y, Liao J, Shih JW, Cheung TH, Lo KW, Yim SF, Yip SK, Ngong DT, Siu N, ... ... Denhardt DT, et al. Expression genomics of cervical cancer: molecular classification and prediction of radiotherapy response by DNA microarray. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5486-92. PMID 14654527  0.25
2003 Shapses SA, Cifuentes M, Spevak L, Chowdhury H, Brittingham J, Boskey AL, Denhardt DT. Osteopontin facilitates bone resorption, decreasing bone mineral crystallinity and content during calcium deficiency Calcified Tissue International. 73: 86-92. PMID 14506959 DOI: 10.1007/S00223-002-1090-X  0.396
2003 Morinobu M, Ishijima M, Rittling SR, Tsuji K, Yamamoto H, Nifuji A, Denhardt DT, Noda M. Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1706-15. PMID 12968681 DOI: 10.1359/Jbmr.2003.18.9.1706  0.404
2003 Hampel DJ, Sansome C, Romanov VI, Kowalski AJ, Denhardt DT, Goligorsky MS. Osteopontin traffic in hypoxic renal epithelial cells. Nephron. Experimental Nephrology. 94: e66-76. PMID 12845232 DOI: 10.1159/000071285  0.675
2003 Chellaiah MA, Biswas RS, Rittling SR, Denhardt DT, Hruska KA. Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts. The Journal of Biological Chemistry. 278: 29086-97. PMID 12730217 DOI: 10.1074/Jbc.M211074200  0.382
2003 Matsui Y, Rittling SR, Okamoto H, Inobe M, Jia N, Shimizu T, Akino M, Sugawara T, Morimoto J, Kimura C, Kon S, Denhardt D, Kitabatake A, Uede T. Osteopontin deficiency attenuates atherosclerosis in female apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1029-34. PMID 12730087 DOI: 10.1161/01.Atv.0000074878.29805.D0  0.417
2003 Kitahara K, Ishijima M, Rittling SR, Tsuji K, Kurosawa H, Nifuji A, Denhardt DT, Noda M. Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation. Endocrinology. 144: 2132-40. PMID 12697722 DOI: 10.1210/En.2002-220996  0.403
2003 Denhardt DT, Mistretta D, Chambers AF, Krishna S, Porter JF, Raghuram S, Rittling SR. Transcriptional regulation of osteopontin and the metastatic phenotype: evidence for a Ras-activated enhancer in the human OPN promoter. Clinical & Experimental Metastasis. 20: 77-84. PMID 12650610 DOI: 10.1023/A:1022550721404  0.439
2003 Denhardt DT. Commentary re: Q-T Le et al, identification of osteopontin as a prognostic marker for head and neck squamous cell carcinomas. clin cancer res, 9: 31-32, 2003. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 31-2. PMID 12538448  0.217
2003 Chellaiah MA, Kizer N, Biswas R, Alvarez U, Strauss-Schoenberger J, Rifas L, Rittling SR, Denhardt DT, Hruska KA. Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression. Molecular Biology of the Cell. 14: 173-89. PMID 12529435 DOI: 10.1091/Mbc.E02-06-0354  0.426
2002 Suzuki K, Zhu B, Rittling SR, Denhardt DT, Goldberg HA, McCulloch CAG, Sodek J. Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts Journal of Bone and Mineral Research. 17: 1486-1497. PMID 12162503 DOI: 10.1359/Jbmr.2002.17.8.1486  0.427
2002 Khan SA, Lopez-Chua CA, Zhang J, Fisher LW, Sørensen ES, Denhardt DT. Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors. Journal of Cellular Biochemistry. 85: 728-36. PMID 11968013 DOI: 10.1002/Jcb.10170  0.599
2002 D'Alonzo RC, Kowalski AJ, Denhardt DT, Nickols GA, Partridge NC. Regulation of collagenase-3 and osteocalcin gene expression by collagen and osteopontin in differentiating MC3T3-E1 cells. The Journal of Biological Chemistry. 277: 24788-98. PMID 11964409 DOI: 10.1074/Jbc.M202604200  0.701
2002 Yumoto K, Ishijima M, Rittling SR, Tsuji K, Tsuchiya Y, Kon S, Nifuji A, Uede T, Denhardt DT, Noda M. Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 4556-61. PMID 11930008 DOI: 10.1073/Pnas.052523599  0.427
2002 Ishijima M, Tsuji K, Rittling SR, Yamashita T, Kurosawa H, Denhardt DT, Nifuji A, Noda M. Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 661-7. PMID 11918223 DOI: 10.1359/Jbmr.2002.17.4.661  0.395
2002 Potter MR, Rittling SR, Denhardt DT, Roper RJ, Weis JH, Teuscher C, Weis JJ. Role of osteopontin in murine Lyme arthritis and host defense against Borrelia burgdorferi. Infection and Immunity. 70: 1372-81. PMID 11854223 DOI: 10.1128/Iai.70.3.1372-1381.2002  0.412
2001 Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (New York, N.Y.). 294: 1731-5. PMID 11721059 DOI: 10.1126/Science.1062960  0.375
2001 Denhardt DT, Burger EH, Kazanecki C, Krishna S, Semeins CM, Klein-Nulend J. Osteopontin-deficient bone cells are defective in their ability to produce NO in response to pulsatile fluid flow Biochemical and Biophysical Research Communications. 288: 448-453. PMID 11606063 DOI: 10.1006/Bbrc.2001.5780  0.788
2001 Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. Osteopontin as a means to cope with environmental insults: Regulation of inflammation, tissue remodeling, and cell survival Journal of Clinical Investigation. 107: 1055-1061. PMID 11342566 DOI: 10.1172/Jci12980  0.466
2001 Nemoto H, Rittling SR, Yoshitake H, Furuya K, Amagasa T, Tsuji K, Nifuji A, Denhardt DT, Noda M. Osteopontin Deficiency Reduces Experimental Tumor Cell Metastasis to Bone and Soft Tissues Journal of Bone and Mineral Research. 16: 652-659. PMID 11315992 DOI: 10.1359/Jbmr.2001.16.4.652  0.421
2001 Ihara H, Denhardt DT, Furuya K, Yamashita T, Muguruma Y, Tsuji K, Hruska KA, Higashio K, Enomoto S, Nifuji A, Rittling SR, Noda M. Parathyroid Hormone-induced Bone Resorption Does Not Occur in the Absence of Osteopontin Journal of Biological Chemistry. 276: 13065-13071. PMID 11278791 DOI: 10.1074/Jbc.M010938200  0.417
2001 Denhardt DT, Giachelli CM, Rittling SR. Role of osteopontin in cellular signaling and toxicant injury Annual Review of Pharmacology and Toxicology. 41: 723-749. PMID 11264474 DOI: 10.1146/Annurev.Pharmtox.41.1.723  0.47
2001 Attur MG, Dave MN, Stuchin S, Kowalski AJ, Steiner G, Abramson SB, Denhardt DT, Amin AR. Osteopontin: an intrinsic inhibitor of inflammation in cartilage. Arthritis and Rheumatism. 44: 578-84. PMID 11263772 DOI: 10.1002/1529-0131(200103)44:3<578::Aid-Anr106>3.0.Co;2-7  0.679
2001 Asou Y, Rittling SR, Yoshitake H, Tsuji K, Shinomiya K, Nifuji A, Denhardt DT, Noda M. Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone. Endocrinology. 142: 1325-1332. PMID 11181551 DOI: 10.1210/Endo.142.3.8006  0.408
2001 Ishijima M, Rittling SR, Yamashita T, Tsuji K, Kurosawa H, Nifuji A, Denhardt DT, Noda M. Enhancement of osteoclastic bone resorption and suppression of osteoblastic bone formation in response to reduced mechanical stress do not occur in the absence of osteopontin Journal of Experimental Medicine. 193: 399-404. PMID 11157060 DOI: 10.1084/Jem.193.3.399  0.424
2000 Bonvini JM, Schatzmann U, Beck-Schimmer B, Sun LK, Rittling SR, Denhardt DT, LE Hir M, Wüthrich RP. Lack of in vivo function of osteopontin in experimental anti-GBM nephritis. Journal of the American Society of Nephrology : Jasn. 11: 1647-1655. PMID 10966489 DOI: 10.1681/ASN.V1191647  0.363
2000 Wu Y, Denhardt DT, Rittling SR. Osteopontin is required for full expression of the transformed phenotype by the ras oncogene British Journal of Cancer. 83: 156-163. PMID 10901364 DOI: 10.1054/Bjoc.2000.1200  0.427
2000 Tian JY, Sørensen ES, Butler WT, Lopez CA, Sy MS, Desai NK, Denhardt DT. Regulation of NO synthesis induced by inflammatory mediators in RAW264.7 cells: Collagen prevents inhibition by osteopontin Cytokine. 12: 450-457. PMID 10857758 DOI: 10.1006/Cyto.1999.0634  0.442
2000 Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, Rittling SR, Denhardt DT, Glimcher MJ, Cantor H. Eta-1 (osteopontin): An early component of type-1 (cell-mediated) immunity Science. 287: 860-864. PMID 10657301 DOI: 10.1126/Science.287.5454.860  0.389
1999 Noiri E, Dickman K, Miller F, Romanov G, Romanov VI, Shaw R, Chambers AF, Rittling SR, Denhardt DT, Goligorsky MS. Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. Kidney International. 56: 74-82. PMID 10411681 DOI: 10.1046/J.1523-1755.1999.00526.X  0.395
1999 Yoshitake H, Rittling SR, Denhardt DT, Noda M. Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption Proceedings of the National Academy of Sciences of the United States of America. 96: 8156-8160. PMID 10393964 DOI: 10.1073/Pnas.96.14.8156  0.431
1999 Denhardt DT, Rittling SR. Osteopontin function in pathology: Lessons from osteopontin-deficient mice Experimental Nephrology. 7: 103-113. PMID 10213864 DOI: 10.1159/000020591  0.422
1999 Mundel P, Shankland SJ, Horton MA, Hart S, Pröls F, Hartner A, Schöcklmann HO, Sterzel RB, Norman JT, Fine LG, Rosenkranz AR, Mayadas TN, Wilson PD, Burrow CR, Fogo AB, ... ... Denhardt DT, et al. Adhesion Molecules in Renal Disease Nephron Experimental Nephrology. 7: 75-77. DOI: 10.1159/000020588  0.321
1998 Denhardt DT, Noda M. Osteopontin expression and function: Role in bone remodeling. Journal of Cellular Biochemistry. 72: 92-102. PMID 29345811 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<92::Aid-Jcb13>3.0.Co;2-A  0.49
1998 Denhardt DT, Noda M. Osteopontin expression and function: role in bone remodeling Journal of Cellular Biochemistry. Supplement. 30: 92-102. PMID 9893260  0.403
1998 Rittling SR, Matsumoto HN, McKee MD, Nanci A, An XR, Novick KE, Kowalski AJ, Noda M, Denhardt DT. Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 13: 1101-11. PMID 9661074 DOI: 10.1359/Jbmr.1998.13.7.1101  0.709
1998 Rajan SS, Lackland H, Stein S, Denhardt DT. Presence of an N-terminal polyhistidine tag facilitates stable expression of an otherwise unstable n-terminal domain of mouse tissue inhibitor of metalloproteinase-1 in Escherichia coli Protein Expression and Purification. 13: 67-72. PMID 9631517 DOI: 10.1006/Prep.1998.0883  0.432
1998 Rajan SS, Denhardt DT, Lackland H, Ludescher RD. Analysis of the conformational stability of the active domain of recombinant mouse TIMP-1 by intrinsic fluorescence. Biochemical and Biophysical Research Communications. 242: 303-9. PMID 9446789 DOI: 10.1006/Bbrc.1997.7960  0.369
1997 Bonnelye E, Vanacker JM, Dittmar T, Begue A, Desbiens X, Denhardt DT, Aubin JE, Laudet V, Fournier B. The ERR-1 orphan receptor is a transcriptional activator expressed during bone development. Molecular Endocrinology (Baltimore, Md.). 11: 905-16. PMID 9178750 DOI: 10.1210/Mend.11.7.9948  0.471
1997 Matsue M, Kageyama R, Denhardt DT, Noda M. Helix-loop-helix-type transcription factor (HES-1) is expressed in osteoblastic cells, suppressed by 1,25(OH)2 vitamin D3, and modulates 1,25(OH)2 vitamin D3 enhancement of osteopontin gene expression Bone. 20: 329-334. PMID 9108352 DOI: 10.1016/S8756-3282(97)00005-7  0.311
1997 Brunner S, Kramar K, Denhardt DT, Hofbauer R. Cloning and characterization of murine carnitine acetyltransferase: Evidence for a requirement during cell cycle progression Biochemical Journal. 322: 403-410. PMID 9065756 DOI: 10.1042/Bj3220403  0.446
1996 Denhardt DT. Oncogene-lnitiated Aberrant Signaling Engenders the Metastatic Phenotype: Synergistic Transcription Factor Interactions are Targets for Cancer Therapy Critical Reviews in Oncogenesis. 7: 261-291. PMID 9258606 DOI: 10.1615/Critrevoncog.V7.I3-4.70  0.411
1996 Walther SE, Denhardt DT. Directed mutagenesis reveals that two histidines in tissue inhibitor of metalloproteinase-1 are each essential for the suppression of cell migration, invasion, and tumorigenicity Cell Growth and Differentiation. 7: 1579-1588. PMID 8930408  0.354
1996 Rollo EE, Denhardt DT. Differential effects of osteopontin on the cytotoxic activity of macrophages from young and old mice Immunology. 88: 642-647. PMID 8881770 DOI: 10.1046/J.1365-2567.1996.D01-691.X  0.432
1996 Denhardt DT. Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: The potential for multiplex signalling Biochemical Journal. 318: 729-747. PMID 8836113 DOI: 10.1042/Bj3180729  0.401
1996 Rollo EE, Laskin DL, Denhardt DT. Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages Journal of Leukocyte Biology. 60: 397-404. PMID 8830797 DOI: 10.1002/Jlb.60.3.397  0.444
1996 Tezuka KI, Denhardt DT, Rodan GA, Harada SI. Stimulation of mouse osteopontin promoter by v-Src is mediated by a CCAAT box-binding factor Journal of Biological Chemistry. 271: 22713-22717. PMID 8798445 DOI: 10.1074/Jbc.271.37.22713  0.464
1996 Malyankar UM, Rittling SR, Denhardt DT. Instability of endogenous MRP/proliferin transcripts in the nucleus of mouse embryo fibroblasts contrasts with their stability when produced during transient transfections Journal of Cellular Biochemistry. 60: 198-210. PMID 8655630 DOI: 10.1002/(Sici)1097-4644(19960201)60:2<198::Aid-Jcb4>3.0.Co;2-S  0.415
1996 Liu AC, Chen KY, Denhardt DT. Foreword Biological Signals. 5: 127-129.  0.266
1995 Guo X, Paul Zhang Y, Mitchell DA, Denhardt DT, Chambers AF. Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with the metastatic potential of the cell Molecular and Cellular Biology. 15: 476-487. PMID 7799957 DOI: 10.1128/Mcb.15.1.476  0.439
1995 Behrend EI, Craig AM, Wilson SM, Denhardt DT, Chambers AF. Expression of antisense osteopontin RNA in metastatic mouse fibroblasts is associated with reduced malignancy. Annals of the New York Academy of Sciences. 760: 299-301. PMID 7785904 DOI: 10.1111/J.1749-6632.1995.Tb44640.X  0.371
1995 Noda M, Denhardt DT. Regulation of osteopontin gene expression in osteoblasts Annals of the New York Academy of Sciences. 760: 242-248. PMID 7785898 DOI: 10.1111/J.1749-6632.1995.Tb44634.X  0.389
1995 Feng B, Rollo EE, Denhardt DT. Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotoxicity: evidence from cell lines down-regulated for OPN expression by a targeted ribozyme Clinical &Amp; Experimental Metastasis. 13: 453-462. PMID 7586803 DOI: 10.1007/Bf00118184  0.477
1995 Lopez CA, Olson ES, Adams JC, Mou K, Denhardt DT, Davis RL. Osteopontin expression detected in adult cochleae and inner ear fluids. Hearing Research. 85: 210-22. PMID 7559176 DOI: 10.1016/0378-5955(95)00046-7  0.426
1995 Matsumoto HN, Tamura M, Denhardt DT, Obinata M, Noda M. Establishment and characterization of bone marrow stromal cell lines that support osteoclastogenesis Endocrinology. 136: 4084-4091. PMID 7544276 DOI: 10.1210/Endo.136.9.7544276  0.468
1995 Lopez CA, Davis RL, Mou K, Denhardt DT. Activation of a signal transduction pathway by osteopontin Annals of the New York Academy of Sciences. 760: 324-326. PMID 7540377 DOI: 10.1111/J.1749-6632.1995.Tb44648.X  0.326
1995 Denhardt DT, Lopez CA, Rollo EE, Hwang SM, An XR, Walther SE. Osteopontin-induced modifications of cellular functions Annals of the New York Academy of Sciences. 760: 127-142. PMID 7540371 DOI: 10.1111/J.1749-6632.1995.Tb44625.X  0.458
1994 Malyankar UM, Rittling SR, Connor A, Denhardt DT. The mitogen-regulated protein/proliferin transcript is degraded in primary mouse embryo fibroblast but not 3T3 nuclei: altered RNA processing correlates with immortalization. Proceedings of the National Academy of Sciences of the United States of America. 91: 335-339. PMID 8278389 DOI: 10.1073/Pnas.91.1.335  0.435
1994 Cocuzzi ET, Walther SE, Denhardt DT. Expression and secretion of active mouse TIMP-1 using a baculovirus expression vector Inflammation. 18: 35-43. PMID 8206645 DOI: 10.1007/Bf01534596  0.442
1994 Giachelli CM, Pichler R, Lombardi D, Denhardt DT, Alpers CE, Schwartz SM, Johnson RJ. Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis Kidney International. 45: 515-524. PMID 8164440 DOI: 10.1038/Ki.1994.67  0.412
1994 Xuan JW, Kowalski J, Chambers AF, Denhardt DT. A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase Genomics. 20: 129-131. PMID 8020941 DOI: 10.1006/Geno.1994.1139  0.403
1994 Denhardt DT, Rajan S, Walther SE. Structure-function studies of mouse tissue inhibitor of metalloproteinases-1 Annals of the New York Academy of Sciences. 732: 65-74. PMID 7978852 DOI: 10.1111/J.1749-6632.1994.Tb24725.X  0.345
1994 Denhardt DT, Chambers AF. Overcoming obstacles to metastasis - defenses against host defenses: Osteopontin (OPN) as a shield against attack by cytotoxic host cells Journal of Cellular Biochemistry. 56: 48-51. PMID 7528752 DOI: 10.1002/Jcb.240560109  0.461
1994 Garcia-Welsh A, Laskin DL, Hwang SM, Denhardt DT, Laskin JD. Production of nitric oxide by differentiated LSTRA cells is associated with expression of macrophage-inducible nitric oxide synthase Journal of Leukocyte Biology. 56: 488-494. PMID 7523558 DOI: 10.1002/Jlb.56.4.488  0.397
1994 Hwang SM, Wilson PD, Laskin JD, Denhardt DT. Age and development-related changes in osteopontin and nitric oxide synthase mRNA levels in human kidney proximal tubule epithelial cells: contrasting responses to hypoxia and reoxygenation. Journal of Cellular Physiology. 160: 61-8. PMID 7517407 DOI: 10.1002/Jcp.1041600108  0.418
1994 Hwang SM, Lopez CA, Heck DE, Gardner CR, Laskin DL, Laskin JD, Denhardt DT. Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells Journal of Biological Chemistry. 269: 711-715. PMID 7506262  0.366
1993 Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques Journal of Clinical Investigation. 92: 1686-1696. PMID 8408622 DOI: 10.1172/Jci116755  0.378
1993 Lopez CA, Hoyer JR, Wilson PD, Waterhouse P, Denhardt DT. Heterogeneity of osteopontin expression among nephrons in mouse kidneys and enhanced expression in sclerotic glomeruli. Laboratory Investigation; a Journal of Technical Methods and Pathology. 69: 355-63. PMID 8377476  0.35
1993 Waterhouse P, Denhardt DT, Khokha R. Temporal expression of tissue inhibitors of metalloproteinases in mouse reproductive tissues during gestation Molecular Reproduction and Development. 35: 219-226. PMID 8352925 DOI: 10.1002/Mrd.1080350302  0.391
1993 Denhardt DT, Feng B, Edwards DR, Cocuzzi ET, Malyankar UM. Tissue inhibitor of metalloproteinases (TIMP, aka EPA): Structure, control of expression and biological functions Pharmacology and Therapeutics. 59: 329-341. PMID 8309995 DOI: 10.1016/0163-7258(93)90074-N  0.426
1993 Denhardt DT, Guo X. Osteopontin: A protein with diverse functions Faseb Journal. 7: 1475-1482. PMID 8262332 DOI: 10.1096/Fasebj.7.15.8262332  0.432
1993 Behrend EI, Chambers AF, Wilson SM, Denhardt DT. Comparative analysis of two alternative first exons reported for the mouse osteopontin gene Journal of Biological Chemistry. 268: 11172-11175. PMID 7684372  0.296
1992 Chambers AF, Colella R, Denhardt DT, Wilson SM. Increased expression of cathepsins L and B and decreased activity of their inhibitors in metastatic, ras-transformed NIH 3T3 cells Molecular Carcinogenesis. 5: 238-245. PMID 1586450 DOI: 10.1002/Mc.2940050311  0.403
1992 Chambers AF, Behrend EI, Wilson SM, Denhardt DT. Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells Anticancer Research. 12: 43-47. PMID 1567180  0.333
1992 Denhardt DT. Antisense strategies come of age. Antisense strategies sponsored by the New York Academy of Sciences, Philadelphia, PA, USA, January 12-15, 1992 The New Biologist. 4: 473-481. PMID 1515412  0.187
1992 Waterhouse P, Parhar RS, Guo X, Lala PK, Denhardt DT. Regulated temporal and spatial expression of the calcium-binding proteins calcyclin and OPN (osteopontin) in mouse tissues during pregnancy Molecular Reproduction and Development. 32: 315-323. PMID 1497879 DOI: 10.1002/Mrd.1080320403  0.396
1992 Denhardt DT, Khokha R, Yagel S, Overall CM, Parhar RS. Oncogenic consequences of down-modulating TIMP expression in 3T3 cells with antisense RNA Matrix (Stuttgart, Germany). Supplement. 1: 281-285. PMID 1480038  0.377
1992 Rittling SR, Denhardt DT. p53 mutations in spontaneously immortalized 3T12 but not 3T3 mouse embryo cells Oncogene. 7: 935-942. PMID 1349164  0.298
1992 Denhardt DT. Mechanism of action of antisense RNA. Sometime inhibition of transcription, processing, transport, or translation Annals of the New York Academy of Sciences. 660: 70-76. PMID 1340158 DOI: 10.1111/J.1749-6632.1992.Tb21059.X  0.398
1992 Bo Feng, Denhardt DT. Inhibition of processing of the primary transcript of the gene encoding tissue inhibitor of metalloproteinases (TIMP) by antisense TIMP RNA in mouse 3T3 cells Annals of the New York Academy of Sciences. 660: 280-282. PMID 1340135 DOI: 10.1111/J.1749-6632.1992.Tb21085.X  0.403
1992 Cocuzzi ET, Walther SE, Rajan S, Denhardt DT. Expression and purification of mouse TIMP-1 from E. coli Febs Letters. 307: 375-378. PMID 1322839 DOI: 10.1016/0014-5793(92)80716-T  0.43
1992 Denhardt DT. Conference summary Annals of the New York Academy of Sciences. 660: 342-345. DOI: 10.1111/j.1749-6632.1992.tb21108.x  0.214
1991 Khokka R, Waterhouse P, Lala P, Zimmer M, Denhardt DT. Increased proteinase expression during tumor progression of tissue inhibitor of metalloproteinases cell lines down-modulated for levels: a new transformation paradigm? Journal of Cancer Research and Clinical Oncology. 117: 333-338. PMID 2066353 DOI: 10.1007/Bf01630716  0.445
1991 Craig AM, Denhardt DT. The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone. Gene. 100: 163-71. PMID 2055467 DOI: 10.1016/0378-1119(91)90362-F  0.446
1991 Nilsen-Hamilton M, Jang YJ, Delgado M, Shim JK, Bruns K, Chiang CP, Fang Y, Parfett CL, Denhardt DT, Hamilton RT. Regulation of the expression of mitogen-regulated protein (MRP; proliferin) and cathepsin L in cultured cells and in the murine placenta. Molecular and Cellular Endocrinology. 77: 115-22. PMID 1815996 DOI: 10.1016/0303-7207(91)90065-Z  0.429
1991 Hofbauer R, Denhardt DT. Cell cycle-regulated and proliferation stimulus-responsive genes Critical Reviews in Eukaryotic Gene Expression. 1: 247-300. PMID 1802111  0.28
1991 Hamilton RT, Bruns KA, Delgado MA, Shim JK, Fang Y, Denhardt DT, Nilsen-Hamilton M. Developmental expression of cathepsin L and c-rasHa in the mouse placenta. Molecular Reproduction and Development. 30: 285-92. PMID 1751032 DOI: 10.1002/Mrd.1080300402  0.353
1991 Denhardt DT, Edwards DR, Mcleod M, Norton G, Parfett CLJ, Zimmer M. Spontaneous immortalization of mouse embryo cells: Strain differences and changes in gene expression with particular reference to retroviral gag-pol genes Experimental Cell Research. 192: 128-136. PMID 1701724 DOI: 10.1016/0014-4827(91)90167-S  0.449
1991 Khokha R, Waterhouse P, Lala P, Zimmer M, Denhardt DT. Increased proteinase expression during tumor progression of cell lines down-modulated for TIMP levels: a new transformation paradigm? Journal of Cancer Research and Clinical Oncology. 117: 620. DOI: 10.1007/Bf01613299  0.445
1990 Craig AM, Bowden GT, Chambers AF, Spearman MA, Greenberg AH, Wright JA, McLeod M, Denhardt DT. Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. International Journal of Cancer. Journal International Du Cancer. 46: 133-7. PMID 2365496 DOI: 10.1002/Ijc.2910460124  0.479
1990 Chan JC, Scanlon M, Denhardt DT, Singh K, Mukherjee BB, Farach-Carson MC, Butler WT. Immunochemical comparison of transformation-associated protein and secreted phosphoprotein International Journal of Cancer. 46: 864-870. PMID 2228315 DOI: 10.1002/Ijc.2910460519  0.394
1990 Waterhouse P, Khokha R, Denhardt DT. Modulation of translation by the 5′ leader sequence of the mRNA encoding murine tissue inhibitor of metalloproteinases Journal of Biological Chemistry. 265: 5585-5589. PMID 2180930  0.311
1990 Noda M, Vogel RL, Craig AM, Prahl J, DeLuca HF, Denhardt DT. Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression. Proceedings of the National Academy of Sciences of the United States of America. 87: 9995-9. PMID 2175918 DOI: 10.1073/Pnas.87.24.9995  0.398
1989 Connor AM, Waterhouse P, Khokha R, Denhardt DT. Characterization of a mouse mitogen-regulated protein/proliferin gene and its promoter: a member of the growth hormone/prolactin gene superfamily Bba - Gene Structure and Expression. 1009: 75-82. PMID 2790033 DOI: 10.1016/0167-4781(89)90081-X  0.4
1989 Yagel S, Warner AH, Nellans HN, Lala PK, Waghorne C, Denhardt DT. Suppression by cathepsin L inhibitors of the invasion of amnion membranes by murine cancer cells. Cancer Research. 49: 3553-7. PMID 2731177  0.293
1989 Craig AM, Smith JH, Denhardt DT. Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. The Journal of Biological Chemistry. 264: 9682-9. PMID 2722855  0.398
1989 Smith JH, Denhardt DT. Evidence for two pathways of protein kinase C induction of 2ar expression: Correlation with mitogenesis Journal of Cellular Physiology. 139: 189-195. PMID 2708455 DOI: 10.1002/Jcp.1041390126  0.451
1989 Khokha R, Denhardt DT. Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion Invasion and Metastasis. 9: 391-405. PMID 2689386  0.233
1989 Kowalski J, Denhardt DT. Regulation of the mRNA for monocyte-derived neutrophil-activating peptide in differentiating HL60 promyelocytes Molecular and Cellular Biology. 9: 1946-1957. PMID 2664463 DOI: 10.1128/Mcb.9.5.1946  0.417
1989 Parfett CLJ, Hofbauer R, Brudzynski K, Edwards DR, Denhardt DT. Differential screening of a cDNA library with cDNA probes amplified in a heterologous host: isolation of murine GRP78 (BiP) and other serum-regulated low-abundance mRNAs Gene. 82: 291-303. PMID 2583523 DOI: 10.1016/0378-1119(89)90054-1  0.407
1989 Yagel S, Khokha R, Denhardt DT, Kerbel RS, Parhar RS, Lala PK. Mechanisms of cellular invasiveness: A comparison of amnion invasion in vitro and metastatic behavior in vivo Journal of the National Cancer Institute. 81: 768-775. PMID 2541259 DOI: 10.1093/Jnci/81.10.768  0.399
1989 Khokha R, Waterhouse P, Yagel S, Lala PK, Overall CM, Norton G, Denhardt DT. Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells Science. 243: 947-950. PMID 2465572 DOI: 10.1126/Science.2465572  0.418
1988 Denhardt DT, Kowalski J. Is there induced DNA repair in mammalian cells? Bioessays. 9: 70-72. PMID 3223968 DOI: 10.1002/Bies.950090208  0.435
1988 Denhardt DT, Edwards DR, Kowalski J, Parfett CL, Waterhouse P. Specialized plasmid vectors for cloning cDNA Biotechnology (Reading, Mass.). 10: 237-251. PMID 3061516 DOI: 10.1016/B978-0-409-90042-2.50018-0  0.347
1988 Denhardt DT, Colasanti J. A survey of vectors for regulating expression of cloned DNA in E. coli Biotechnology (Reading, Mass.). 10: 179-203. PMID 3061514 DOI: 10.1016/B978-0-409-90042-2.50015-5  0.464
1988 Craig AM, Nemir M, Mukherjee BB, Chambers AF, Denhardt DT. Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells. Biochemical and Biophysical Research Communications. 157: 166-73. PMID 3058125 DOI: 10.1016/S0006-291X(88)80028-7  0.444
1988 Denhardt DT, Chaly N, Walden DB. The eukaryotic nucleus: A thematic issue Bioessays. 9: 43-43. DOI: 10.1002/Bies.950090202  0.305
1987 Edwards DR, Parfett CLJ, Smith JH, Denhardt DT. Evidence that post-transcriptional changes in the expression of mitogen regulated protein accompany immortalization of mouse cells Biochemical and Biophysical Research Communications. 147: 467-473. PMID 3632680 DOI: 10.1016/S0006-291X(87)80144-4  0.438
1987 Smith JH, Denhardt DT. Molecular cloning of a tumor promoter-inducible mRNA found in JB6 mouse epidermal cells: induction is stable at high, but not at low, cell densities Journal of Cellular Biochemistry. 34: 13-22. PMID 3584260 DOI: 10.1002/Jcb.240340103  0.427
1987 Denhardt DT, Greenberg AH, Egan SE, Hamilton RT, Wright JA. Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts. Oncogene. 2: 55-9. PMID 3438085  0.302
1987 Gilchrist CA, Denhardt DT. Escherichia coli rep gene: Sequence of the gene, the encoded helicase, and its homology with uvrD Nucleic Acids Research. 15: 465-475. PMID 3029683 DOI: 10.1093/Nar/15.2.465  0.402
1987 Colasanti J, Denhardt DT. Mechanism of replication of bacteriophage φX174 XXII. Site-specific mutagenesis of the A* gene reveals that A* protein is not essential for φX174 DNA replication Journal of Molecular Biology. 197: 47-54. PMID 2960819 DOI: 10.1016/0022-2836(87)90608-5  0.453
1987 Colasanti J, Denhardt DT. The Escherichia coli rep mutation. X. Consequences of increased and decreased Rep protein levels Mgg Molecular &Amp; General Genetics. 209: 382-390. PMID 2959842 DOI: 10.1007/Bf00329669  0.461
1987 Khokha R, Denhardt DT. On the use of anti-sense RNA: Down-regulation of mRNA encoding a metalloproteinase inhibitor Anticancer Research. 7: 653-660. PMID 2444152  0.276
1986 Denhardt DT, Hamilton RT, Parfett CL, Edwards DR, St Pierre R, Waterhouse P, Nilsen-Hamilton M. Close relationship of the major excreted protein of transformed murine fibroblasts to thiol-dependent cathepsins. Cancer Research. 46: 4590-3. PMID 3755373  0.342
1986 Denhardt DT, Edwards DR, Parfett CLJ. Gene expression during the mammalian cell cycle Bba - Reviews On Cancer. 865: 83-125. PMID 3533155 DOI: 10.1016/0304-419X(86)90024-7  0.417
1986 Edwards DR, Waterhouse P, Holman ML, Denhardt DT. A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: Evidence for inducible and constitutive transcripts Nucleic Acids Research. 14: 8863-8878. PMID 3024122 DOI: 10.1093/Nar/14.22.8863  0.436
1985 Edwards DR, Parfett CL, Denhardt DT. A pBR322-derived vector for cloning blunt-ended cDNA: its use to detect molecular clones of low-abundance mRNAs Dna. 4: 401-408. PMID 3865759 DOI: 10.1089/DNA.1985.4.401  0.291
1985 Parfett CL, Hamilton RT, Howell BW, Edwards DR, Nilsen-Hamilton M, Denhardt DT. Characterization of a cDNA clone encoding murine mitogen-regulated protein: regulation of mRNA levels in mortal and immortal cell lines. Molecular and Cellular Biology. 5: 3289-92. PMID 3841805 DOI: 10.1128/Mcb.5.11.3289  0.428
1985 Edwards DR, Parfett CLJ, Denhardt DT. Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: Equivalence of one species to B2 repetitive elements Molecular and Cellular Biology. 5: 3280-3288. PMID 3837843 DOI: 10.1128/Mcb.5.11.3280  0.388
1985 Colasanti J, Denhardt DT. Expression of the cloned bacteriophage ΦX174 A gene in Escherichia coli inhibits DNA replication and cell division Journal of Virology. 53: 807-813. PMID 3156255  0.407
1985 Bialkowska-Hobrzanska H, Gilchrist CA, Denhardt DT. Escherichia coli rep gene: Identification of the promoter and N terminus of the rep protein Journal of Bacteriology. 164: 1004-1010. PMID 2999067 DOI: 10.1128/Jb.164.3.1004-1010.1985  0.398
1985 Kowalski J, Smith JH, Ng N, Denhardt DT. Vectors for the direct selection of cDNA clones corresponding to mammalian cell mRNA of low abundance Gene. 35: 45-54. PMID 2863196 DOI: 10.1016/0378-1119(85)90156-8  0.408
1985 Edwards DR, Denhardt DT. A study of mitochondrial and nuclear transcription with cloned cDNA probes. Changes in the relative abundance of mitochondrial transcripts after stimulation of quiescent mouse fibroblasts Experimental Cell Research. 157: 127-143. PMID 2578968 DOI: 10.1016/0014-4827(85)90157-0  0.373
1985 Denhardt DT, Faust EA. Eukaryotic DNA replication Bioessays. 2: 148-154. DOI: 10.1002/Bies.950020403  0.4
1984 Denhardt DT. DNA replication: A twofold amplifed view Nature. 309: 515. PMID 6728007 DOI: 10.1038/309515A0  0.392
1984 Bialkowska-Hobrzanska H, Denhardt DT. The rep mutation VII. Cloning and analysis of the functional rep gene of Escherichia coli K-12 Gene. 28: 93-102. PMID 6234203 DOI: 10.1016/0378-1119(84)90091-X  0.419
1983 Bondy GP, Denhardt DT. Exposure of JB-6 mouse epidermal cells to 12-O-tetradecanoyl-phorbol-13-acetate is not accompanied by a significant change in total DNA-cytosine methylation Carcinogenesis. 4: 1599-1603. PMID 6652872 DOI: 10.1093/Carcin/4.12.1599  0.427
1983 Denhardt DT, Miyamoto C. Characteristics of the nascent and non-nascent small DNA molecules found in Escherichia coli Journal of Molecular Biology. 165: 419-442. PMID 6188847 DOI: 10.1016/S0022-2836(83)80211-3  0.418
1982 Kowalski J, Denhardt DT. Adenovirus DNA replication in vivo. Properties of short DNA molecules extracted from infected cells Bba - Gene Structure and Expression. 698: 260-270. PMID 7138868 DOI: 10.1016/0167-4781(82)90156-7  0.419
1982 Matthes M, Denhardt DT. Mechanism of replication of bacteriophage ΦX174. XX. Sensitivity of nascent DNA to single-strand-specific nucleases Journal of Virology. 42: 12-19. PMID 6283133  0.299
1982 Matthes M, Weisbeek PJ, Denhardt DT. Mechanism of replication of bacteriophage ΦX174. XIX. Initiation of ΦX174 viral strand DNA synthesis at internal sites on the genome Journal of Virology. 42: 301-305. PMID 6211552  0.32
1981 Dubeau L, Hours C, Denhardt DT. The mechanism of replication of ΦX174 XVII. Purification and partial characterization of the gene A and A(c) proteins Canadian Journal of Biochemistry. 59: 106-115. PMID 6453639 DOI: 10.1139/O81-016  0.417
1981 Narkhammar-Meuth M, Kowalski J, Denhardt DT. Both strands of polyoma DNA are replicated discontinuously with ribonucleotide primers in vivo Journal of Virology. 39: 21-30. PMID 6268811  0.326
1981 Dubeau L, Denhardt DT. The mechanism of replication of ΦX174. XVIII. Gene A and A* proteins of ΦX174 bind tightly to ΦX174 replicative form DNA Bba Section Nucleic Acids and Protein Synthesis. 653: 52-60. PMID 6261820 DOI: 10.1016/0005-2787(81)90103-9  0.431
1980 Crawford LV, Lane DP, Denhardt DT, Harlow EE, Nicklin PM, Osborn K, Pim DC. Characterization of the complex between SV40 large T antigen and the 53K host protein in transformed mouse cells. Cold Spring Harbor Symposia On Quantitative Biology. 44: 179-87. PMID 6253132 DOI: 10.1101/Sqb.1980.044.01.021  0.378
1980 Denhardt DT, Crawford LV. Simian virus 40 T-antigen: Identification of tryptic peptides in the C-terminal region and definition of the reading frame Journal of Virology. 34: 315-329. PMID 6246267 DOI: 10.1128/Jvi.34.2.315-329.1980  0.383
1980 Matthes M, Denhardt DT. The mechanism of replication of φX174 DNA. XVI. Evidence that the φX174 viral strand is synthesized discontinuously Journal of Molecular Biology. 136: 45-63. PMID 6245220 DOI: 10.1016/0022-2836(80)90365-4  0.419
1979 Denhardt DT, Kowalski J, Miyamoto C. Evidence for many nonnascent DNA molecules the size of Okazaki fragments in Escherichia coli and 3T3 cells: Very few have 5'-terminal ribonucleotides Cold Spring Harbor Symposia On Quantitative Biology. 43: 243-252. PMID 383379  0.324
1979 Takahashi S, Hours C, Chu A, Denhardt DT. The rep mutation. VI. Purification and properties of the Escherichia coli rep protein, DNA helicase III Canadian Journal of Biochemistry. 57: 855-866. PMID 383240 DOI: 10.1139/O79-105  0.454
1979 Hours C, Denhardt DT. "Nick translation" in Escherichia coli rep strains deficient in DNA polymerase I activities Mgg Molecular &Amp; General Genetics. 172: 73-80. PMID 377026 DOI: 10.1007/Bf00276217  0.428
1979 Denhardt DT. DNA gyrase and DNA unwinding Nature. 280: 196-198. PMID 221839 DOI: 10.1038/280196A0  0.383
1979 Kowalski J, Denhardt DT. Ribonucleotides in DNA newly synthesised in 3T6 cells in vivo [27] Nature. 281: 704-706. PMID 95207 DOI: 10.1038/281704A0  0.447
1978 Kowalski J, Denhardt DT. Most short DNA molecules isolated from 3T3 cells are not nascent Nucleic Acids Research. 5: 4355-4374. PMID 724517 DOI: 10.1093/Nar/5.11.4355  0.405
1978 Matthes M, Denhardt DT. Comparison of restriction endonuclease HaeIII fragments of φX174, φXtB, and St-1: Evidence that φXtB is St-1 Virology. 85: 626-627. PMID 664218 DOI: 10.1016/0042-6822(78)90469-5  0.406
1978 Denhardt DT, Dressler D, Ray DS. Preface/Front Matter Cold Spring Harbor Monograph Archive. 8. DOI: 10.1101/087969122.8.I  0.396
1978 Denhardt DT. Overview: A Comparison of the Isometric and Filamentous Phages Cold Spring Harbor Monograph Archive. 8: 645-655. DOI: 10.1101/087969122.8.645  0.372
1978 Takahashi S, Hours C, Iwaya M, Lane HED, Denhardt DT. The Escherichia coli rep Gene Cold Spring Harbor Monograph Archive. 8: 393-400. DOI: 10.1101/087969122.8.393  0.377
1978 Hours C, Matthes M, Miyamoto N, Denhardt DT. Nascent Pieces of ϕ X174 Viral-strand DNA Are Shorter Than Unit-length and Are Derived from All Regions of the Genome Cold Spring Harbor Monograph Archive. 8: 245-253. DOI: 10.1101/087969122.8.245  0.416
1977 Woodworth-gutai M, Lebowitz J, Kato AC, Denhardt DT. Ultraviolet light irradiation of PM2 superhelical DNA Nucleic Acids Research. 4: 1243-1256. PMID 896460 DOI: 10.1093/Nar/4.5.1243  0.354
1977 Miyamoto C, Denhardt DT. Evidence for the presence of ribonucleotides at the 5′ termini of some DNA molecules isolated from Escherichia coli polAex2 Journal of Molecular Biology. 116: 681-707. PMID 338924 DOI: 10.1016/0022-2836(77)90266-2  0.415
1977 McFadden G, Denhardt DT. Contrasting effects of 2′,3′-dideoxyadenosine on two steps in the replication of φX174 DNA in Escherichia coli Virology. 76: 870-875. PMID 320756 DOI: 10.1016/0042-6822(77)90268-9  0.419
1977 Takahashi S, Hours C, Denhardt DT. Specialized transduction of the rep gene of Escherichia coli Fems Microbiology Letters. 2: 279-283. DOI: 10.1111/J.1574-6968.1977.Tb00960.X  0.347
1977 Fraenkel-Carrat H, Wagner RR, Denhardt DT. Comprehensive virology Plenum Publ.Corp., New York 0.323
1976 Denhardt DT, Eisenberg S, Bartok K, Carter BJ. Multiple structures of adeno associated virus DNA: analysis of terminally labeled molecules with endonuclease R.HaeIII Journal of Virology. 18: 672-684. PMID 1271522 DOI: 10.1128/Jvi.18.2.672-684.1976  0.418
1976 Bartok K, Denhardt DT. Site of cleavage of superhelical phiX174 replicative form DNA by the single strand specific Neurospora crassa endonuclease Journal of Biological Chemistry. 251: 530-535. PMID 942717  0.304
1975 Carter BJ, Khoury G, Denhardt DT. Physical map and strand polarity of specific fragments of adenovirus associated virus DNA produced by endonuclease R.EcoRI Journal of Virology. 16: 559-568. PMID 1159894  0.297
1975 McFadden G, Denhardt DT. The mechanism of replication of øX174 DNA. XIII. Discontinuous synthesis of the complementary strand in an escherichia coli host with a temperature-sensitive polynucleotide ligase Journal of Molecular Biology. 99: 125-142. PMID 1107560 DOI: 10.1016/S0022-2836(75)80163-X  0.416
1975 Eisenberg S, Harbers B, Hours C, Denhardt DT. The mechanism of replication of phiX174 DNA. XII. Non random location of gaps in nascent phiX174 RF II DNA Journal of Molecular Biology. 99: 107-123. PMID 1107559 DOI: 10.1016/S0022-2836(75)80162-8  0.412
1975 Denhardt DT, Model P. The single-stranded DNA phages Critical Reviews in Microbiology. 4: 161-223. PMID 1106952 DOI: 10.3109/10408417509111575  0.29
1975 David Lane HE, Denhardt DT. The rep mutation. IV. Slower movement of replication forks in Escherichia coli rep strains Journal of Molecular Biology. 97. PMID 1100854 DOI: 10.1016/S0022-2836(75)80025-8  0.416
1975 Bartok K, Harbers B, Denhardt DT. Isolation and characterization of self-complementary sequences from øX174 viral DNA Journal of Molecular Biology. 99. PMID 128634 DOI: 10.1016/S0022-2836(75)80161-6  0.405
1975 Eisenberg S, Harbers B, Hours C, Denhardt DT. The mechanism of replication of øX174 DNA. XII. Non-random location of gaps in nascent øX174 RF II DNA Journal of Molecular Biology. 99. DOI: 10.1016/S0022-2836(75)80162-8  0.289
1974 Kato AC, Borstad L, Fraser MJ, Denhardt DT. Isolation of repeated and self-complementary sequences from E.coli DNA Nucleic Acids Research. 1: 1539-1548. PMID 10793709 DOI: 10.1093/Nar/1.11.1539  0.395
1974 Lane HE, Denhardt DT. The rep mutation. III. Altered structure of the replicating Escherichia coli chromosome Journal of Bacteriology. 120: 805-814. PMID 4616950 DOI: 10.1128/Jb.120.2.805-814.1974  0.408
1974 Eisenberg S, Denhardt DT. The mechanism of replication of φX174 single-stranded DNA X. Distribution of the gaps in nascent φX174 replicative form DNA Biochemical and Biophysical Research Communications. 61: 532-537. PMID 4616690 DOI: 10.1016/0006-291X(74)90989-9  0.421
1974 McFadden G, Denhardt DT. Mechanism of replication of phiX174 single stranded DNA. IX. Requirement for the Escherichia coli dnaG protein Journal of Virology. 14: 1070-1075. PMID 4610175 DOI: 10.1128/Jvi.14.5.1070-1075.1974  0.414
1974 Eisenberg S, Denhardt DT. Structure of nascent phiX174 replicative form: evidence for discontinuous DNA replication Proceedings of the National Academy of Sciences of the United States of America. 71: 984-988. PMID 4522806 DOI: 10.1073/Pnas.71.3.984  0.424
1973 Denhardt DT, Kato AC. Comparison of the effect of ultraviolet radiation and ethidium bromide intercalation on the conformation of superhelical φX174 replicative form DNA Journal of Molecular Biology. 77. PMID 4723947 DOI: 10.1016/0022-2836(73)90217-9  0.401
1973 Iwaya M, Eisenberg S, Bartok K, Denhardt DT. Mechanism of replication of single stranded phiX174 DNA. VII. Circularization of the progeny viral strand Journal of Virology. 12: 808-818. PMID 4591049 DOI: 10.1128/Jvi.12.4.808-818.1973  0.408
1973 Denhardt DT, Iwaya M, McFadden G, Schochetman G. The mechanism of replication of phiX174 single stranded DNA. VI. Requirements for ribonucleoside triphosphates and DNA polymerase III Canadian Journal of Biochemistry. 51: 1588-1597. PMID 4590554 DOI: 10.1139/O73-214  0.42
1973 Iwaya M, Denhardt DT. Mechanism of replication of φX174 single-stranded DNA. V. Dispersive and conservative transfer of parental DNA into progeny DNA Journal of Molecular Biology. 73: 291-305. PMID 4568498 DOI: 10.1016/0022-2836(73)90343-4  0.384
1973 Iwaya M, Denhardt DT. Mechanism of replication of φX174 single-stranded DNA. IV. The parental viral strand is not conserved in the replicating DNA structure Journal of Molecular Biology. 73: 279-290. PMID 4568497 DOI: 10.1016/0022-2836(73)90342-2  0.415
1973 Kato AC, Bartok K, Fraser MJ, Denhardt DT. Sensitivity of superhelical DNA to a single-strand specific endonuclease Bba Section Nucleic Acids and Protein Synthesis. 308: 68-78. PMID 4269186 DOI: 10.1016/0005-2787(73)90123-8  0.39
1972 Denhardt DT. A theory of DNA replication Journal of Theoretical Biology. 34: 487-508. PMID 4588125 DOI: 10.1016/0022-5193(72)90137-3  0.409
1972 Denhardt DT, Iwaya M, Larison LL. The rep mutation. II. Its effect on Escherichia coli and on the replication of bacteriophage ∅X174 Virology. 49: 486-496. PMID 4559689 DOI: 10.1016/0042-6822(72)90500-4  0.434
1971 Schekman RW, Iwaya M, Bromstrup K, Denhardt DT. The mechanism of replication of phi X174 single-stranded DNA. 3. An enzymic study of the structure of the replicative form II DNA. Journal of Molecular Biology. 57: 177-99. PMID 4931510 DOI: 10.1016/0022-2836(71)90340-8  0.668
1971 Iwaya M, Denhardt DT. The mechanism of replication of φX174 single-stranded DNA. II. The role of viral proteins Journal of Molecular Biology. 57: 159-175. PMID 4931509 DOI: 10.1016/0022-2836(71)90339-1  0.425
1970 Altman S, Denhardt DT. Evidence for preferential breakage of the minus strand of ΦX174 replicative form DNA by a T4-induced endonuclease Bba Section Nucleic Acids and Protein Synthesis. 224: 21-28. PMID 4923222 DOI: 10.1016/0005-2787(70)90616-7  0.401
1969 Denhardt DT, Marvin DA. Altered coding in single stranded DNA viruses? Nature. 221: 769-770. PMID 5766650 DOI: 10.1038/221769A0  0.406
1969 Burgess AB, Denhardt DT. Studies on φX174 proteins. I. Phage-specific proteins synthesized after infection of Escherichia coli Journal of Molecular Biology. 44. PMID 4899472 DOI: 10.1016/0022-2836(69)90367-2  0.409
1969 Denhardt DT. Formation of ribosylthymine in Escherichia coli. Studies on pulse labeling with thymine and thymidine Journal of Biological Chemistry. 244: 2710-2715. PMID 4890229  0.231
1968 Dressler DH, Denhardt DT. Mechanism of replication of φx-174 single stranded DNA Nature. 219: 346-351. PMID 5662147 DOI: 10.1038/219346A0  0.394
1968 Cairns J, Denhardt DT. Effect of cyanide and carbon monoxide on the replication of bacterial DNA in vivo Journal of Molecular Biology. 36: 335-342. PMID 4939630 DOI: 10.1016/0022-2836(68)90159-9  0.404
1968 Steinberg RA, Denhardt DT. Inhibition of synthesis of φX174 DNA in a mutant host thermosensitive for DNA synthesis Journal of Molecular Biology. 37: 525-528. PMID 4888152 DOI: 10.1016/0022-2836(68)90120-4  0.401
1968 Denhardt DT. Effect of antiserum to E. coli DNA polymerase on synthesis of ΦxI74 DNA in extracts of Φx-infected cells Nature. 220: 131-134. PMID 4879322 DOI: 10.1038/220131A0  0.419
1968 Denhardt DT, Burgess AB. DNA replication in vitro. I. Synthesis of single-stranded phi X174 DNA in crude lysates of phi X-infected E. coli Cold Spring Harbor Symposia On Quantitative Biology. 33: 449-457. PMID 4306817 DOI: 10.1101/Sqb.1968.033.01.052  0.396
1967 Denhardt DT, Dressler DH, Hathaway A. THE ABORTIVE REPLICATION OF PhiX174 DNA IN A RECOMBINATION-DEFICIENT MUTANT OF Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 57: 813-20. PMID 16591535 DOI: 10.1073/Pnas.57.3.813  0.409
1966 Denhardt DT. A membrane-filter technique for the detection of complementary DNA Biochemical and Biophysical Research Communications. 23: 641-646. PMID 5963888 DOI: 10.1016/0006-291X(66)90447-5  0.339
1966 Denhardt DT, Silver RB. An analysis of the clone size distribution of phi-X-174 mutants and recombinants. Virology. 30: 10-9. PMID 5911886 DOI: 10.1016/S0042-6822(66)81004-8  0.378
1965 Denhardt DT, Sinsheimer RL. The process of infection with bacteriophage phi-XD174. VI. Inactivation of infected complexes by ultraviolet irradiation Journal of Molecular Biology. 12: 674-694. PMID 5323482 DOI: 10.1016/S0022-2836(65)80321-7  0.593
1965 Denhardt DT, Sinsheimer RL. The process of infection with bacteriophage phi-X174. IV. Replication of the viral DNA in a synchronized infection Journal of Molecular Biology. 12: 647-662. PMID 5323481 DOI: 10.1016/S0022-2836(65)80319-9  0.59
1965 Denhardt DT, Sinsheimer RL. The process of infection with bacteriophage phi-X174. 3. Phage maturation and lysis after synchronized infection Journal of Molecular Biology. 12: 641-646. PMID 5323480 DOI: 10.1016/S0022-2836(65)80318-7  0.555
1965 Denhardt DT. Teaching by research fellows Science. 149: 920. DOI: 10.1126/Science.149.3687.918-B  0.294
1965 Denhardt DT, Sinsheimer RL. The Process of Infection with Bacteriophage φX174: V. Inactivation of the Phage-Bacterium Complex by Decay of ^(32)P incorporated in the Infecting Particle Journal of Molecular Biology. 12: 663-673. DOI: 10.1016/S0022-2836(65)80320-5  0.573
1960 Denhardt DT. A possible basis for Immunological tolerance Nature. 186: 728-729. PMID 13815912 DOI: 10.1038/186728B0  0.386
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