Charles J. Waechter - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Cell Biology, Microbiology Biology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Rush JS, Subramanian T, Subramanian KL, Onono FO, Waechter CJ, Spielmann HP. Novel Citronellyl-Based Photoprobes Designed to Identify ER Proteins Interacting with Dolichyl Phosphate in Yeast and Mammalian Cells. Current Chemical Biology. 9: 123-141. PMID 27099830 DOI: 10.2174/2212796810666160216221610  0.38
2013 Yang AC, Ng BG, Moore SA, Rush J, Waechter CJ, Raymond KM, Willer T, Campbell KP, Freeze HH, Mehta L. Congenital disorder of glycosylation due to DPM1 mutations presenting with dystroglycanopathy-type congenital muscular dystrophy. Molecular Genetics and Metabolism. 110: 345-51. PMID 23856421 DOI: 10.1016/J.Ymgme.2013.06.016  0.377
2011 Harrison KD, Park EJ, Gao N, Kuo A, Rush JS, Waechter CJ, Lehrman MA, Sessa WC. Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation. The Embo Journal. 30: 2490-500. PMID 21572394 DOI: 10.1038/Emboj.2011.147  0.447
2010 Rush JS, Matveev S, Guan Z, Raetz CR, Waechter CJ. Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2{Delta} mutant and CHO cells. Glycobiology. 20: 1585-93. PMID 20685834 DOI: 10.1093/Glycob/Cwq107  0.539
2010 Rush JS, Alaimo C, Robbiani R, Wacker M, Waechter CJ. A novel epimerase that converts GlcNAc-P-P-undecaprenol to GalNAc-P-P-undecaprenol in Escherichia coli O157. The Journal of Biological Chemistry. 285: 1671-80. PMID 19923219 DOI: 10.1074/Jbc.M109.061630  0.463
2009 Rush JS, Gao N, Lehrman MA, Matveev S, Waechter CJ. Suppression of Rft1 expression does not impair the transbilayer movement of Man5GlcNAc2-P-P-dolichol in sealed microsomes from yeast. The Journal of Biological Chemistry. 284: 19835-42. PMID 19494107 DOI: 10.1074/Jbc.M109.000893  0.512
2008 Frank CG, Sanyal S, Rush JS, Waechter CJ, Menon AK. Does Rft1 flip an N-glycan lipid precursor? Nature. 454: E3-4; discussion E4-. PMID 18668045 DOI: 10.1038/Nature07165  0.364
2008 Rush JS, Gao N, Lehrman MA, Waechter CJ. Recycling of dolichyl monophosphate to the cytoplasmic leaflet of the endoplasmic reticulum after the cleavage of dolichyl pyrophosphate on the lumenal monolayer. The Journal of Biological Chemistry. 283: 4087-93. PMID 18077451 DOI: 10.1074/Jbc.M707067200  0.512
2007 Hartman MC, Jiang S, Rush JS, Waechter CJ, Coward JK. Glycosyltransferase mechanisms: impact of a 5-fluoro substituent in acceptor and donor substrates on catalysis. Biochemistry. 46: 11630-8. PMID 17883281 DOI: 10.1021/Bi700863S  0.362
2006 Rush JS, Waechter CJ. Partial purification of mannosylphosphorylundecaprenol synthase from Micrococcus luteus: a useful enzyme for the biosynthesis of a variety of mannosylphosphorylpolyisoprenol products. Methods in Molecular Biology (Clifton, N.J.). 347: 13-30. PMID 17072001 DOI: 10.1385/1-59745-167-3:13  0.447
2006 Shridas P, Waechter CJ. Human dolichol kinase, a polytopic endoplasmic reticulum membrane protein with a cytoplasmically oriented CTP-binding site. The Journal of Biological Chemistry. 281: 31696-704. PMID 16923818 DOI: 10.1074/Jbc.M604087200  0.364
2005 Rush JS, Waechter CJ. Assay for the transbilayer movement of polyisoprenoid-linked saccharides based on the transport of water-soluble analogues. Methods (San Diego, Calif.). 35: 316-22. PMID 15804602 DOI: 10.1016/J.Ymeth.2004.10.002  0.329
2005 Pakkiri LS, Waechter CJ. Dimannosyldiacylglycerol serves as a lipid anchor precursor in the assembly of the membrane-associated lipomannan in Micrococcus luteus. Glycobiology. 15: 291-302. PMID 15483271 DOI: 10.1093/Glycob/Cwi003  0.454
2004 Rush JS, Waechter CJ. Functional reconstitution into proteoliposomes and partial purification of a rat liver ER transport system for a water-soluble analogue of mannosylphosphoryldolichol. Biochemistry. 43: 7643-52. PMID 15182207 DOI: 10.1021/Bi036083O  0.411
2004 Pakkiri LS, Wolucka BA, Lubert EJ, Waechter CJ. Structural and topological studies on the lipid-mediated assembly of a membrane-associated lipomannan in Micrococcus luteus. Glycobiology. 14: 73-81. PMID 14551219 DOI: 10.1093/Glycob/Cwh012  0.436
2003 Shridas P, Rush JS, Waechter CJ. Identification and characterization of a cDNA encoding a long-chain cis-isoprenyltranferase involved in dolichyl monophosphate biosynthesis in the ER of brain cells. Biochemical and Biophysical Research Communications. 312: 1349-56. PMID 14652022 DOI: 10.1016/J.Bbrc.2003.11.065  0.422
2003 Wu X, Rush JS, Karaoglu D, Krasnewich D, Lubinsky MS, Waechter CJ, Gilmore R, Freeze HH. Deficiency of UDP-GlcNAc:Dolichol Phosphate N-Acetylglucosamine-1 Phosphate Transferase (DPAGT1) causes a novel congenital disorder of Glycosylation Type Ij. Human Mutation. 22: 144-50. PMID 12872255 DOI: 10.1002/Humu.10239  0.373
2003 Rick PD, Barr K, Sankaran K, Kajimura J, Rush JS, Waechter CJ. Evidence that the wzxE gene of Escherichia coli K-12 encodes a protein involved in the transbilayer movement of a trisaccharide-lipid intermediate in the assembly of enterobacterial common antigen. The Journal of Biological Chemistry. 278: 16534-42. PMID 12621029 DOI: 10.1074/jbc.M301750200  0.373
2002 Fernandez F, Shridas P, Jiang S, Aebi M, Waechter CJ. Expression and characterization of a human cDNA that complements the temperature-sensitive defect in dolichol kinase activity in the yeast sec59-1 mutant: the enzymatic phosphorylation of dolichol and diacylglycerol are catalyzed by separate CTP-mediated kinase activities in Saccharomyces cerevisiae. Glycobiology. 12: 555-62. PMID 12213788 DOI: 10.1093/Glycob/Cwf068  0.42
2002 Rush JS, Cho SK, Jiang S, Hofmann SL, Waechter CJ. Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells. The Journal of Biological Chemistry. 277: 45226-34. PMID 12198133 DOI: 10.1074/Jbc.M207076200  0.532
2001 Fernandez F, Rush JS, Toke DA, Han GS, Quinn JE, Carman GM, Choi JY, Voelker DR, Aebi M, Waechter CJ. The CWH8 gene encodes a dolichyl pyrophosphate phosphatase with a luminally oriented active site in the endoplasmic reticulum of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 276: 41455-64. PMID 11504728 DOI: 10.1074/Jbc.M105544200  0.529
2001 Schenk B, Fernandez F, Waechter CJ. The ins(ide) and outs(ide) of dolichyl phosphate biosynthesis and recycling in the endoplasmic reticulum Glycobiology. 11. PMID 11425794 DOI: 10.1093/Glycob/11.5.61R  0.497
2001 Schenk B, Rush JS, Waechter CJ, Aebi M. An alternative cis-isoprenyltransferase activity in yeast that produces polyisoprenols with chain lengths similar to mammalian dolichols. Glycobiology. 11: 89-98. PMID 11181565 DOI: 10.1093/Glycob/11.1.89  0.385
2001 Anand M, Rush JS, Ray S, Doucey MA, Weik J, Ware FE, Hofsteenge J, Waechter CJ, Lehrman MA. Requirement of the Lec35 gene for all known classes of monosaccharide-P-dolichol-dependent glycosyltransferase reactions in mammals. Molecular Biology of the Cell. 12: 487-501. PMID 11179430 DOI: 10.1091/Mbc.12.2.487  0.481
2000 Rush JS, Panneerselvam K, Waechter CJ, Freeze HH. Mannose supplementation corrects GDP-mannose deficiency in cultured fibroblasts from some patients with Congenital Disorders of Glycosylation (CDG). Glycobiology. 10: 829-35. PMID 10929009 DOI: 10.1093/Glycob/10.8.829  0.448
1999 Thai L, Rush JS, Maul JE, Devarenne T, Rodgers DL, Chappell J, Waechter CJ. Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions. Proceedings of the National Academy of Sciences of the United States of America. 96: 13080-5. PMID 10557276 DOI: 10.1073/Pnas.96.23.13080  0.418
1999 Andres DA, Crick DC, Finlin BS, Waechter CJ. Rapid identification of cysteine-linked isoprenyl groups by metabolic labeling with [3H]farnesol and [3H]geranylgeraniol. Methods in Molecular Biology (Clifton, N.J.). 116: 107-23. PMID 10399149 DOI: 10.1385/1-59259-264-3:107  0.37
1999 Faulkner A, Chen X, Rush J, Horazdovsky B, Waechter CJ, Carman GM, Sternweis PC. The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae Journal of Biological Chemistry. 274: 14831-14837. PMID 10329682 DOI: 10.1074/Jbc.274.21.14831  0.473
1998 Rush JS, Waechter CJ. Topological studies on the enzymes catalyzing the biosynthesis of Glc-P-dolichol and the triglucosyl cap of Glc3Man9GlcNAc2-P-P-dolichol in microsomal vesicles from pig brain: use of the processing glucosidases I/II as latency markers. Glycobiology. 8: 1207-13. PMID 9858642 DOI: 10.1093/Glycob/8.12.1207  0.493
1998 Rush JS, van Leyen K, Ouerfelli O, Wolucka B, Waechter CJ. Transbilayer movement of Glc-P-dolichol and its function as a glucosyl donor: protein-mediated transport of a water-soluble analog into sealed ER vesicles from pig brain. Glycobiology. 8: 1195-205. PMID 9858641 DOI: 10.1093/Glycob/8.12.1195  0.496
1998 Crick DC, Andres DA, Danesi R, Macchia M, Waechter CJ. Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. Journal of Neurochemistry. 70: 2397-405. PMID 9603204 DOI: 10.1046/J.1471-4159.1998.70062397.X  0.393
1998 Frank DW, Waechter CJ. Purification and characterization of a polyisoprenyl phosphate phosphatase from pig brain. Possible dual specificity. The Journal of Biological Chemistry. 273: 11791-8. PMID 9565603 DOI: 10.1074/Jbc.273.19.11791  0.489
1998 Wolucka BA, Rush JS, Waechter CJ, Shibaev VN, de Hoffmann E. An electrospray-ionization tandem mass spectrometry method for determination of the anomeric configuration of glycosyl 1-phosphate derivatives. Analytical Biochemistry. 255: 244-51. PMID 9451510 DOI: 10.1006/Abio.1997.2421  0.364
1997 Besra GS, Morehouse CB, Rittner CM, Waechter CJ, Brennan PJ. Biosynthesis of mycobacterial lipoarabinomannan Journal of Biological Chemistry. 272: 18460-18466. PMID 9218490 DOI: 10.1074/Jbc.272.29.18460  0.458
1997 Rush JS, Rick PD, Waechter CJ. Polyisoprenyl phosphate specificity of UDP-GlcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase from E.coli. Glycobiology. 7: 315-22. PMID 9134438 DOI: 10.1093/Glycob/7.2.315  0.523
1997 Crick DC, Andres DA, Waechter CJ. Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate. Experimental Cell Research. 231: 302-7. PMID 9087171 DOI: 10.1006/Excr.1997.3480  0.387
1995 Dotson SB, Rush JS, Ricketts AD, Waechter CJ. Mannosylphosphoryldolichol-mediated O-mannosylation of yeast glycoproteins: stereospecificity and recognition of the alpha-isoprene unit by a purified mannosyltransferase. Archives of Biochemistry and Biophysics. 316: 773-9. PMID 7864633 DOI: 10.1006/Abbi.1995.1103  0.445
1995 Crick DC, Andres DA, Waechter CJ. Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. Biochemical and Biophysical Research Communications. 211: 590-9. PMID 7794274 DOI: 10.1006/Bbrc.1995.1854  0.426
1995 Crick DC, Suders J, Kluthe CM, Andres DA, Waechter CJ. Selective inhibition of cholesterol biosynthesis in brain cells by squalestatin 1. Journal of Neurochemistry. 65: 1365-73. PMID 7643114 DOI: 10.1046/J.1471-4159.1995.65031365.X  0.488
1995 Rush JS, Waechter CJ. Transmembrane movement of a water-soluble analogue of mannosylphosphoryldolichol is mediated by an endoplasmic reticulum protein. The Journal of Cell Biology. 130: 529-36. PMID 7622555 DOI: 10.1083/Jcb.130.3.529  0.49
1995 Rush JS, Waechter CJ. Method for the determination of cellular levels of guanosine-5'-diphosphate-mannose based on a weak interaction with concanavalin A at low pH. Analytical Biochemistry. 224: 494-501. PMID 7537473 DOI: 10.1006/Abio.1995.1078  0.479
1994 Crick DC, Waechter CJ. Long-chain cis-isoprenyltransferase activity is induced early in the developmental program for protein N-glycosylation in embryonic rat brain cells. Journal of Neurochemistry. 62: 247-56. PMID 8263525 DOI: 10.1046/J.1471-4159.1994.62010247.X  0.514
1994 Crick DC, Scocca JR, Rush JS, Frank DW, Krag SS, Waechter CJ. Induction of dolichyl-saccharide intermediate biosynthesis corresponds to increased long chain cis-isoprenyltransferase activity during the mitogenic response in mouse B cells. The Journal of Biological Chemistry. 269: 10559-65. PMID 8144643  0.407
1994 Kean EL, Rush JS, Waechter CJ. Activation of GlcNAc-P-P-dolichol synthesis by mannosylphosphoryldolichol is stereospecific and requires a saturated alpha-isoprene unit. Biochemistry. 33: 10508-12. PMID 8068690 DOI: 10.1021/Bi00200A036  0.474
1994 Crick DC, Waechter CJ, Andres DA. Utilization of geranylgeraniol for protein isoprenylation in C6 glial cells. Biochemical and Biophysical Research Communications. 205: 955-61. PMID 7999138 DOI: 10.1006/Bbrc.1994.2758  0.418
1994 DeLuca AW, Rush JS, Lehrman MA, Waechter CJ. Mannolipid donor specificity of glycosylphosphatidylinositol mannosyltransferase-I (GPIMT-I) determined with an assay system utilizing mutant CHO-K1 cells. Glycobiology. 4: 909-15. PMID 7734853 DOI: 10.1093/Glycob/4.6.909  0.417
1992 Rush JS, Klein J, Fanti P, Bhat NR, Waechter CJ. Direct assay of membrane-associated protein kinase C activity in B lymphocytes in the presence of Brij 58. Analytical Biochemistry. 207: 304-10. PMID 1481985 DOI: 10.1016/0003-2697(92)90016-Z  0.41
1992 Rush JS, Waechter CJ. An anion-exchange radioassay for glucose 6-phosphate phosphatase: use in topological studies with endoplasmic reticulum vesicles. Analytical Biochemistry. 206: 328-33. PMID 1332548 DOI: 10.1016/0003-2697(92)90374-G  0.466
1991 Overmeyer JH, Waechter CJ. Regulation of phosphatidylserine decarboxylase in Saccharomyces cerevisiae by inositol and choline: Kinetics of repression and derepression Archives of Biochemistry and Biophysics. 290: 511-516. PMID 1929418 DOI: 10.1016/0003-9861(91)90574-3  0.379
1991 Crick DC, Rush JS, Waechter CJ. Characterization and localization of a long-chain isoprenyltransferase activity in porcine brain: proposed role in the biosynthesis of dolichyl phosphate. Journal of Neurochemistry. 57: 1354-62. PMID 1895109 DOI: 10.1111/J.1471-4159.1991.Tb08301.X  0.493
1991 Rush JS, Sweitzer T, Kent C, Decker GL, Waechter CJ. Biogenesis of the endoplasmic reticulum in activated B lymphocytes: temporal relationships between the induction of protein N-glycosylation activity and the biosynthesis of membrane protein and phospholipid. Archives of Biochemistry and Biophysics. 284: 63-70. PMID 1846517 DOI: 10.1016/0003-9861(91)90264-J  0.432
1991 Bhat NR, Frank DW, Wolf MJ, Waechter CJ. Developmental changes in enzymes involved in dolichyl phosphate metabolism in cultured embryonic rat brain cells. Journal of Neurochemistry. 56: 339-44. PMID 1846175 DOI: 10.1111/J.1471-4159.1991.Tb02600.X  0.484
1991 Rush JS, Waechter CJ. Expression of dolichol-linked saccharide intermediate synthesis during the development of B lymphocytes. Glycobiology. 1: 229-35. PMID 1726646 DOI: 10.1093/Glycob/1.2.229  0.459
1991 Wolf MJ, Rush JS, Waechter CJ. Golgi-enriched membrane fractions from rat brain and liver contain long-chain polyisoprenyl pyrophosphate phosphatase activity. Glycobiology. 1: 405-10. PMID 1668143 DOI: 10.1093/Glycob/1.4.405  0.508
1990 Genain CP, Waechter CJ. Separation of brain dolichol kinase from endogenous activating factors: Evidence that phospholipid enhances the interaction between enzyme and dolichol Journal of Neurochemistry. 54: 855-862. PMID 2154552 DOI: 10.1111/J.1471-4159.1990.Tb02330.X  0.357
1989 Overmeyer JH, Waechter CJ. Assay for phosphatidylserine decarboxylase utilizing DEAE-cellulose column chromatography Analytical Biochemistry. 182: 452-456. PMID 2692476 DOI: 10.1016/0003-2697(89)90622-2  0.351
1988 Bhat NR, Waechter CJ. Induction of N-glycosylation activity in cultured embryonic rat brain cells Journal of Neurochemistry. 50: 375-381. PMID 3335855 DOI: 10.1111/J.1471-4159.1988.Tb02922.X  0.374
1988 Rush JS, Snow EC, Waechter CJ. Glycoprotein biosynthesis in B lymphocytes: induction of protein N-glycosylation, RNA synthesis, and DNA synthesis by phorbol ester plus ionomycin is blocked by protein kinase inhibitors. Archives of Biochemistry and Biophysics. 267: 305-16. PMID 2461680 DOI: 10.1016/0003-9861(88)90036-7  0.411
1987 Rush JS, Waechter CJ. Inhibitors of protein kinase C block activation of B lymphocytes by bacterial lipopolysaccharide. Biochemical and Biophysical Research Communications. 145: 1315-20. PMID 3496881 DOI: 10.1016/0006-291X(87)91581-6  0.381
1985 Scher MG, Sumbilla CM, Waechter CJ. Dolichyl phosphate metabolism in brain. Developmental increase in polyisoprenyl phosphate phosphatase activity Journal of Biological Chemistry. 260: 13742-13746. PMID 2997180  0.337
1984 Carson MA, Emala M, Hogsten P, Waechter CJ. Coordinate regulation of phosphatidylserine decarboxylase activity and phospholipid N-methylation in yeast Journal of Biological Chemistry. 259: 6267-6273. PMID 6427211  0.329
1984 Scher MG, Devries GH, Waechter CJ. Subcellular sites of enzymes catalyzing the phosphorylation-dephosphorylation of dolichol in the central nervous system. Archives of Biochemistry and Biophysics. 231: 293-302. PMID 6329098 DOI: 10.1016/0003-9861(84)90391-6  0.471
1984 Scher MG, Waechter CJ. Brain dolichyl pyrophosphate phosphatase. Solubilization, characterization, and differentiation from dolichyl monophosphate phosphatase activity Journal of Biological Chemistry. 259: 14580-14585. PMID 6094565  0.384
1983 Rossignol DP, Scher M, Waechter CJ, Lennarz WJ. Metabolic interconversion of dolichol and dolichyl phosphate during development of the sea urchin embryo Journal of Biological Chemistry. 258: 9122-9127. PMID 6307993  0.306
1981 Banerjee DK, Scher MG, Waechter CJ. Amphomycin: Effect of the lipopeptide antibiotic on the glycosylation and extraction of dolichyl monophosphate in calf brain membranes Biochemistry. 20: 1561-1568. PMID 7225346  0.427
1981 Burton WA, Scher MG, Waechter CJ. Enzymatic dephosphorylation of endogenous and exogenous dolichyl monophosphate by calf brain membranes Archives of Biochemistry and Biophysics. 208: 409-417. PMID 6266346 DOI: 10.1016/0003-9861(81)90526-9  0.354
1973 Waechter CJ, Lester RL. Differential regulation of the N-methyl transferases responsible for phosphatidylcholine synthesis in Saccharomyces cerevisiae Archives of Biochemistry and Biophysics. 158: 401-410. PMID 4580845 DOI: 10.1016/0003-9861(73)90637-1  0.394
1971 Waechter CJ, Lester RL. Regulation of phosphatidylcholine biosynthesis in Saccharomyces cerevisiae Journal of Bacteriology. 105: 837-843. PMID 5547992 DOI: 10.1128/Jb.105.3.837-843.1971  0.312
1969 Steiner S, Smith S, Waechter CJ, Lester RL. Isolation and partial characterization of a major inositol-containing lipid in baker's yeast, mannosyl-diinositol, diphosphoryl-ceramide Proceedings of the National Academy of Sciences of the United States of America. 64: 1042-1048. PMID 4313330 DOI: 10.1073/Pnas.64.3.1042  0.325
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