Ganes C. Sen - Publications

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Molecular Biology, Microbiology Biology

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sharma N, Qi X, Kessler P, Sen GC. Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon. Biorxiv : the Preprint Server For Biology. PMID 38260325 DOI: 10.1101/2024.01.08.574713  0.355
2023 Sharma N, Kessler P, Sen GC. Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses. Journal of Virology. e0130423. PMID 37982645 DOI: 10.1128/jvi.01304-23  0.357
2023 Wang C, Sharma N, Kessler PM, Sen GC. Interferon induction by STING requires its translocation to the late endosomes. Traffic (Copenhagen, Denmark). PMID 37658794 DOI: 10.1111/tra.12918  0.362
2022 Popli S, Chakravarty S, Fan S, Glanz A, Aras S, Nagy LE, Sen GC, Chakravarti R, Chattopadhyay S. IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121385119. PMID 36067309 DOI: 10.1073/pnas.2121385119  0.35
2021 Wang C, Sharma N, Veleeparambil M, Kessler PM, Willard B, Sen GC. STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk. Mbio. 12: e0322821. PMID 34933455 DOI: 10.1128/mbio.03228-21  0.347
2021 Sharma N, Wang C, Kessler P, Sen GC. Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis. Plos Pathogens. 17: e1009950. PMID 34591940 DOI: 10.1371/journal.ppat.1009950  0.324
2021 Raja R, Sen GC. The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3. Cell Death and Differentiation. PMID 34545182 DOI: 10.1038/s41418-021-00870-4  0.357
2020 Wang C, Wang X, Veleeparambil M, Kessler PM, Willard B, Chattopadhyay S, Sen GC. EGFR-mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions. The Embo Journal. e104106. PMID 32926474 DOI: 10.15252/Embj.2019104106  0.394
2020 Sen GC, Williams BRG. Peter Lengyel (1929-2020): A Pioneer Researcher in Protein Synthesis and Interferon Action. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 40: 331-332. PMID 32701409 DOI: 10.1089/Jir.2020.29017.Mem  0.317
2020 Farabaugh KT, Krokowski D, Guan BJ, Gao Z, Gao XH, Wu J, Jobava R, Ray G, de Jesus TJ, Bianchi MG, Chukwurah E, Bussolati O, Kilberg M, Buchner DA, Sen GC, et al. PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation. Elife. 9. PMID 32175843 DOI: 10.7554/Elife.52241  0.379
2020 Latif MB, Raja R, Kessler PM, Sen GC. Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of HSV-1 Replication. Journal of Virology. PMID 31896590 DOI: 10.1128/Jvi.01717-19  0.422
2019 Kimura T, Flynn CT, Alirezaei M, Sen GC, Whitton JL. Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection. Plos Pathogens. 15: e1007674. PMID 30958867 DOI: 10.1371/Journal.Ppat.1007674  0.425
2019 Sanz-Garcia C, Poulsen KL, Bellos D, Wang H, McMullen MR, Li X, Chattopadhyay S, Sen G, Nagy LE. The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute on chronic ethanol administration in mice. Journal of Hepatology. PMID 30710579 DOI: 10.1016/J.Jhep.2019.01.021  0.373
2018 Cai G, Zhu L, Chen X, Sun K, Liu C, Sen GC, Stark GR, Qin J, Li X. TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30352854 DOI: 10.1073/Pnas.1809599115  0.336
2018 Veleeparambil M, Poddar D, Abdulkhalek S, Kessler PM, Yamashita M, Chattopadhyay S, Sen GC. Constitutively Bound EGFR-Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal. Journal of Immunology (Baltimore, Md. : 1950). PMID 29531172 DOI: 10.4049/Jimmunol.1700691  0.406
2018 Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, et al. Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. The Embo Journal. PMID 29496741 DOI: 10.15252/Embj.201797858  0.401
2018 Subramanian G, Kuzmanovic T, Zhang Y, Peter CB, Veleeparambil M, Chakravarti R, Sen GC, Chattopadhyay S. A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7. Plos Pathogens. 14: e1006877. PMID 29381763 DOI: 10.1371/Journal.Ppat.1006877  0.468
2017 Davis BM, Fensterl V, Lawrence TM, Hudacek AW, Sen GC, Schnell MJ. Ifit2 is a Restriction Factor in Rabies Virus Pathogenicity. Journal of Virology. PMID 28637751 DOI: 10.1128/Jvi.00889-17  0.422
2016 Chattopadhyay S, Sen GC. RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway. Protein & Cell. PMID 27815826 DOI: 10.1007/S13238-016-0334-X  0.454
2016 Wang X, Majumdar T, Kessler P, Ozhegov E, Zhang Y, Chattopadhyay S, Barik S, Sen GC. STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection. Cell Host & Microbe. 20: 329-341. PMID 27631700 DOI: 10.1016/J.Chom.2016.08.002  0.414
2016 Chattopadhyay S, Kuzmanovic T, Zhang Y, Wetzel JL, Sen GC. Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis. Immunity. PMID 27178468 DOI: 10.1016/J.Immuni.2016.04.009  0.502
2016 White CL, Kessler PM, Dickerman BK, Ozato K, Sen GC. Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members. The Journal of Biological Chemistry. PMID 27137933 DOI: 10.1074/Jbc.M115.705467  0.397
2015 Fensterl V, Chattopadhyay S, Sen GC. No Love Lost Between Viruses and Interferons. Annual Review of Virology. 2: 549-72. PMID 26958928 DOI: 10.1146/Annurev-Virology-100114-055249  0.448
2015 Dickerman BK, White CL, Kessler PM, Sadler AJ, Williams BR, Sen GC. The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development. The Febs Journal. PMID 26414443 DOI: 10.1111/Febs.13533  0.417
2015 Tseng YY, Liao GR, Sen GC, Lin FY, Hsu WL. Regulation of PACT-mediated PKR activation by the OV20.0 protein of orf virus. Journal of Virology. PMID 26355092 DOI: 10.1128/Jvi.01739-15  0.46
2015 Chattopadhyay S, Veleeparambil M, Poddar D, Abdulkhalek S, Bandyopadhyay SK, Fensterl V, Sen GC. EGFR kinase activity is required for TLR4 signaling and the septic shock response. Embo Reports. PMID 26341626 DOI: 10.15252/Embr.201540337  0.391
2015 Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen GC, Barik S. Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. Plos Pathogens. 11: e1004779. PMID 25811886 DOI: 10.1371/Journal.Ppat.1004779  0.459
2015 Fensterl V, Sen GC. Interferon-induced Ifit proteins: their role in viral pathogenesis. Journal of Virology. 89: 2462-8. PMID 25428874 DOI: 10.1128/Jvi.02744-14  0.491
2014 Chakraborty S, Li L, Puliyappadamba VT, Guo G, Hatanpaa KJ, Mickey B, Souza RF, Vo P, Herz J, Chen MR, Boothman DA, Pandita TK, Wang DH, Sen GC, Habib AA. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nature Communications. 5: 5811. PMID 25503978 DOI: 10.1038/Ncomms6811  0.32
2014 Wetzel JL, Fensterl V, Sen GC. Sendai virus pathogenesis in mice is prevented by Ifit2 and exacerbated by interferon. Journal of Virology. 88: 13593-601. PMID 25231314 DOI: 10.1128/Jvi.02201-14  0.362
2014 Chattopadhyay S, Sen GC. Tyrosine phosphorylation in Toll-like receptor signaling. Cytokine & Growth Factor Reviews. 25: 533-41. PMID 25022196 DOI: 10.1016/J.Cytogfr.2014.06.002  0.348
2014 Fensterl V, Wetzel JL, Sen GC. Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus. Journal of Virology. 88: 10303-11. PMID 24991014 DOI: 10.1128/Jvi.01341-14  0.364
2014 Chattopadhyay S, Sen GC. dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 427-36. PMID 24905199 DOI: 10.1089/Jir.2014.0034  0.463
2014 Sen GC. Biological functions of double-stranded RNA and its binding proteins. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 413-4. PMID 24905196 DOI: 10.1089/Jir.2014.0062  0.37
2014 Chattopadhyay S, Sen GC. Meet the terminator: The phosphatase PP2A puts brakes on IRF-3 activation. Molecular Cell. 54: 210-1. PMID 24766884 DOI: 10.1016/J.Molcel.2014.04.008  0.369
2014 Butchi NB, Hinton DR, Stohlman SA, Kapil P, Fensterl V, Sen GC, Bergmann CC. Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages. Journal of Virology. 88: 1051-64. PMID 24198415 DOI: 10.1128/Jvi.02272-13  0.369
2013 Dickerman BK, McDonald JA, Sen GC. The Human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2. F1000research. 2: 220. PMID 24715958 DOI: 10.12688/F1000Research.2-220.V2  0.449
2013 Ogolla PS, Portillo JA, White CL, Patel K, Lamb B, Sen GC, Subauste CS. The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen. Plos Pathogens. 9: e1003557. PMID 23990781 DOI: 10.1371/Journal.Ppat.1003557  0.373
2013 Goswami R, Majumdar T, Dhar J, Chattopadhyay S, Bandyopadhyay SK, Verbovetskaya V, Sen GC, Barik S. Viral degradasome hijacks mitochondria to suppress innate immunity. Cell Research. 23: 1025-42. PMID 23877405 DOI: 10.1038/Cr.2013.98  0.39
2013 Cho H, Shrestha B, Sen GC, Diamond MS. A role for Ifit2 in restricting West Nile virus infection in the brain. Journal of Virology. 87: 8363-71. PMID 23740986 DOI: 10.1128/Jvi.01097-13  0.399
2013 Chattopadhyay S, Fensterl V, Zhang Y, Veleeparambil M, Wetzel JL, Sen GC. Inhibition of viral pathogenesis and promotion of the septic shock response to bacterial infection by IRF-3 are regulated by the acetylation and phosphorylation of its coactivators. Mbio. 4. PMID 23532979 DOI: 10.1128/Mbio.00636-12  0.406
2013 Yamashita M, Millward CA, Inoshita H, Saikia P, Chattopadhyay S, Sen GC, Emancipator SN. Antiviral innate immunity disturbs podocyte cell function. Journal of Innate Immunity. 5: 231-41. PMID 23296190 DOI: 10.1159/000345255  0.491
2013 Leonova KI, Brodsky L, Lipchick B, Pal M, Novototskaya L, Chenchik AA, Sen GC, Komarova EA, Gudkov AV. p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs. Proceedings of the National Academy of Sciences of the United States of America. 110: E89-98. PMID 23236145 DOI: 10.1073/Pnas.1216922110  0.398
2013 Chattopadhyay S, Fensterl V, Zhang Y, Veleeparambil M, Yamashita M, Sen GC. Role of interferon regulatory factor 3-mediated apoptosis in the establishment and maintenance of persistent infection by Sendai virus. Journal of Virology. 87: 16-24. PMID 23077293 DOI: 10.1128/Jvi.01853-12  0.438
2013 Chattopadhyay S, Zhang Y, Sen GC. 39 Cytokine. 63: 252. DOI: 10.1016/J.Cyto.2013.06.042  0.426
2012 Sen GC, Fensterl V. Crystal structure of IFIT2 (ISG54) predicts functional properties of IFITs. Cell Research. 22: 1407-9. PMID 22964712 DOI: 10.1038/Cr.2012.130  0.328
2012 Yamashita M, Chattopadhyay S, Fensterl V, Saikia P, Wetzel JL, Sen GC. Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling. Science Signaling. 5: ra50. PMID 22810896 DOI: 10.1126/Scisignal.2002581  0.429
2012 Fensterl V, Wetzel JL, Ramachandran S, Ogino T, Stohlman SA, Bergmann CC, Diamond MS, Virgin HW, Sen GC. Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis. Plos Pathogens. 8: e1002712. PMID 22615570 DOI: 10.1371/Journal.Ppat.1002712  0.345
2012 Yamashita M, Chattopadhyay S, Fensterl V, Zhang Y, Sen GC. A TRIF-independent branch of TLR3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 188: 2825-33. PMID 22323545 DOI: 10.4049/Jimmunol.1103220  0.444
2012 Sen G. I19 Antiviral actions of the interferon-inducible IFIT proteins Cytokine. 59: 495. DOI: 10.1016/J.Cyto.2012.06.309  0.446
2011 Dickerman BK, White CL, Chevalier C, Nalesso V, Charles C, Fouchécourt S, Guillou F, Viriot L, Sen GC, Hérault Y. Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development. Plos One. 6: e28537. PMID 22194846 DOI: 10.1371/Journal.Pone.0028537  0.365
2011 Sears N, Sen GC, Stark GR, Chattopadhyay S. Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation. The Journal of Biological Chemistry. 286: 33037-44. PMID 21816816 DOI: 10.1074/Jbc.M111.257022  0.423
2011 Jha BK, Polyakova I, Kessler P, Dong B, Dickerman B, Sen GC, Silverman RH. Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity. The Journal of Biological Chemistry. 286: 26319-26. PMID 21636578 DOI: 10.1074/Jbc.M111.253443  0.408
2011 White CL, Chattopadhyay S, Sen GC. Phosphatidylinositol 3-kinase signaling delays sendai virus-induced apoptosis by preventing XIAP degradation. Journal of Virology. 85: 5224-7. PMID 21367892 DOI: 10.1128/Jvi.00053-11  0.372
2011 Chattopadhyay S, Yamashita M, Zhang Y, Sen GC. The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication. Journal of Virology. 85: 3708-16. PMID 21307205 DOI: 10.1128/Jvi.02133-10  0.473
2011 Wan Y, Kim TW, Yu M, Zhou H, Yamashita M, Kang Z, Yin W, Wang JA, Thomas J, Sen GC, Stark GR, Li X. The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 186: 3006-14. PMID 21270393 DOI: 10.4049/Jimmunol.1003217  0.38
2011 Fensterl V, Sen GC. The ISG56/IFIT1 gene family. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 71-8. PMID 20950130 DOI: 10.1089/Jir.2010.0101  0.472
2011 White CL, Chattopadhyay S, Sen GC. PS2-113. PI3K prolongs survival of Sendai virus infected cells by preventing XIAP degradation Cytokine. 56: 95. DOI: 10.1016/J.Cyto.2011.07.279  0.338
2010 Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, et al. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature. 468: 452-6. PMID 21085181 DOI: 10.1038/Nature09489  0.4
2010 Saikia P, Fensterl V, Sen GC. The inhibitory action of P56 on select functions of E1 mediates interferon's effect on human papillomavirus DNA replication. Journal of Virology. 84: 13036-9. PMID 20926571 DOI: 10.1128/Jvi.01194-10  0.312
2010 Zhu J, Smith K, Hsieh PN, Mburu YK, Chattopadhyay S, Sen GC, Sarkar SN. High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors Journal of Immunology. 184: 5768-5776. PMID 20382888 DOI: 10.4049/Jimmunol.0903559  0.368
2010 Chattopadhyay S, Marques JT, Yamashita M, Peters KL, Smith K, Desai A, Williams BR, Sen GC. Viral apoptosis is induced by IRF-3-mediated activation of Bax. The Embo Journal. 29: 1762-73. PMID 20360684 DOI: 10.1038/Emboj.2010.50  0.477
2010 Chattopadhyay S, Yamashita M, Sen GC. SS8-3 IRF-3 and BAX-mediated cellular apoptosis: a novel antiviral response Cytokine. 52: 74. DOI: 10.1016/J.Cyto.2010.07.309  0.331
2010 Sen GC, Yamashita M, Saikia P, Fensterl V, White C, Chattopadhyay S. CS5-1 Multiple antiviral pathways are activated by TLR3 and RIG-I signaling Cytokine. 52: 70. DOI: 10.1016/J.Cyto.2010.07.294  0.308
2009 Gale M, Sen GC. Viral evasion of the interferon system. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 475-6. PMID 19694549 DOI: 10.1089/Jir.2009.0078  0.45
2009 Peters GA, Dickerman B, Sen GC. Biochemical analysis of PKR activation by PACT. Biochemistry. 48: 7441-7. PMID 19580324 DOI: 10.1021/Bi900433Y  0.397
2009 Peters GA, Seachrist DD, Keri RA, Sen GC. The double-stranded RNA-binding protein, PACT, is required for postnatal anterior pituitary proliferation. Proceedings of the National Academy of Sciences of the United States of America. 106: 10696-701. PMID 19541653 DOI: 10.1073/Pnas.0900735106  0.39
2009 Fensterl V, Sen GC. Interferons and viral infections. Biofactors (Oxford, England). 35: 14-20. PMID 19319841 DOI: 10.1002/Biof.6  0.445
2008 Terenzi F, Saikia P, Sen GC. Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1. The Embo Journal. 27: 3311-21. PMID 19008854 DOI: 10.1038/Emboj.2008.241  0.372
2008 Marques J, Anwar J, Eskildsen-Larsen S, Rebouillat D, Paludan SR, Sen G, Williams BR, Hartmann R. The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain. The Journal of General Virology. 89: 2767-72. PMID 18931074 DOI: 10.1099/vir.0.2008/003558-0  0.402
2008 Fensterl V, White CL, Yamashita M, Sen GC. Novel characteristics of the function and induction of murine p56 family proteins. Journal of Virology. 82: 11045-53. PMID 18768971 DOI: 10.1128/Jvi.01593-08  0.483
2008 Marques JT, White CL, Peters GA, Williams BR, Sen GC. The role of PACT in mediating gene induction, PKR activation, and apoptosis in response to diverse stimuli. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 28: 469-76. PMID 18729737 DOI: 10.1089/Jir.2007.0006  0.456
2008 Chattopadhyay S, Karan G, Sen I, Sen GC. A small region in the angiotensin-converting enzyme distal ectodomain is required for cleavage-secretion of the protein at the plasma membrane. Biochemistry. 47: 8335-41. PMID 18636749 DOI: 10.1021/Bi800702A  0.357
2008 Lu LL, Puri M, Horvath CM, Sen GC. Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1. The Journal of Biological Chemistry. 283: 14269-76. PMID 18362155 DOI: 10.1074/Jbc.M710089200  0.464
2008 Peters K, Chattopadhyay S, Sen GC. IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence. Journal of Virology. 82: 3500-8. PMID 18216110 DOI: 10.1128/Jvi.02536-07  0.434
2008 Peters K, Chattopadhyay S, Sen GC. IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence (Journal of Virology (2008) 82, 7, (3500-3508)) Journal of Virology. 82: 7248. DOI: 10.1128/Jvi.00954-08  0.381
2008 Hartmann R, Justesen J, Sarkar S, Sen G, Yee V. Crystal Structure of the 2′‐Specific and Double‐Stranded RNA‐Activated Interferon‐Induced Antiviral Protein 2′‐5′‐Oligoadenylate Synthetase Scandinavian Journal of Immunology. 59: 617-617. DOI: 10.1111/J.0300-9475.2004.01423S.X  0.402
2008 White CL, Peters GA, Dickerman BK, Desai A, Sen GC. 22 The dsRNA binding protein pact in innate immune signaling Cytokine. 43: 241. DOI: 10.1016/J.Cyto.2008.07.062  0.337
2008 Sen GC, Lu L, Fensterl V, White C, Yamashita M, Saikia P, Chattopadhyay S, Sarkar SN. SY-1 Induction, functions and viral evasion of the ISG56 family of genes Cytokine. 43: 234. DOI: 10.1016/J.Cyto.2008.07.031  0.315
2007 Borden EC, Sen GC, Uze G, Silverman RH, Ransohoff RM, Foster GR, Stark GR. Interferons at age 50: past, current and future impact on biomedicine. Nature Reviews. Drug Discovery. 6: 975-90. PMID 18049472 DOI: 10.1038/Nrd2422  0.399
2007 Sen GC, Sarkar SN. The interferon-stimulated genes: Targets of direct signaling by interferons, double-stranded RNA, and viruses Current Topics in Microbiology and Immunology. 316: 233-250. PMID 17969451 DOI: 10.1007/978-3-540-71329-6_12  0.461
2007 Sen GC, Peters GA. Viral stress-inducible genes. Advances in Virus Research. 70: 233-63. PMID 17765707 DOI: 10.1016/S0065-3527(07)70006-4  0.512
2007 Terenzi F, White C, Pal S, Williams BR, Sen GC. Tissue-specific and inducer-specific differential induction of ISG56 and ISG54 in mice. Journal of Virology. 81: 8656-65. PMID 17553874 DOI: 10.1128/Jvi.00322-07  0.431
2007 Elco CP, Sen GC. Stat1 required for interferon-inducible but not constitutive responsiveness to extracellular dsRNA. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 27: 411-24. PMID 17523873 DOI: 10.1089/Jir.2006.0172  0.411
2007 Kim TW, Staschke K, Bulek K, Yao J, Peters K, Oh KH, Vandenburg Y, Xiao H, Qian W, Hamilton T, Min B, Sen G, Gilmour R, Li X. A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity. The Journal of Experimental Medicine. 204: 1025-36. PMID 17470642 DOI: 10.1084/Jem.20061825  0.359
2007 Min JY, Li S, Sen GC, Krug RM. A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis. Virology. 363: 236-43. PMID 17320139 DOI: 10.1016/J.Virol.2007.01.038  0.658
2007 Sarkar SN, Elco CP, Peters KL, Chattopadhyay S, Sen GC. Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-kappa B activation. The Journal of Biological Chemistry. 282: 3423-7. PMID 17178723 DOI: 10.1074/Jbc.C600226200  0.402
2007 Wacher C, Müller M, Hofer MJ, Getts DR, Zabaras R, Ousman SS, Terenzi F, Sen GC, King NJ, Campbell IL. Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses. Journal of Virology. 81: 860-71. PMID 17079283 DOI: 10.1128/Jvi.01167-06  0.412
2006 Peters GA, Li S, Sen GC. Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis. The Journal of Biological Chemistry. 281: 35129-36. PMID 16982605 DOI: 10.1074/Jbc.M607714200  0.595
2006 Terenzi F, Hui DJ, Merrick WC, Sen GC. Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56 Journal of Biological Chemistry. 281: 34064-34071. PMID 16973618 DOI: 10.1074/Jbc.M605771200  0.742
2006 Chang KS, Cai Z, Zhang C, Sen GC, Williams BR, Luo G. Replication of hepatitis C virus (HCV) RNA in mouse embryonic fibroblasts: protein kinase R (PKR)-dependent and PKR-independent mechanisms for controlling HCV RNA replication and mediating interferon activities. Journal of Virology. 80: 7364-74. PMID 16840317 DOI: 10.1128/Jvi.00586-06  0.373
2006 Li S, Peters GA, Ding K, Zhang X, Qin J, Sen GC. Molecular basis for PKR activation by PACT or dsRNA. Proceedings of the National Academy of Sciences of the United States of America. 103: 10005-10. PMID 16785445 DOI: 10.1073/Pnas.0602317103  0.616
2006 Rowe TM, Rizzi M, Hirose K, Peters GA, Sen GC. A role of the double-stranded RNA-binding protein PACT in mouse ear development and hearing. Proceedings of the National Academy of Sciences of the United States of America. 103: 5823-8. PMID 16571658 DOI: 10.1073/Pnas.0601287103  0.395
2006 Li S, Min JY, Krug RM, Sen GC. Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology. 349: 13-21. PMID 16466763 DOI: 10.1016/J.Virol.2006.01.005  0.667
2005 Prescott J, Ye C, Sen G, Hjelle B. Induction of innate immune response genes by Sin Nombre hantavirus does not require viral replication. Journal of Virology. 79: 15007-15. PMID 16306571 DOI: 10.1128/Jvi.79.24.15007-15015.2005  0.407
2005 Sen GC, Sarkar SN. Hitching RIG to action. Nature Immunology. 6: 1074-6. PMID 16239922 DOI: 10.1038/Ni1105-1074  0.39
2005 Chattopadhyay S, Santhamma KR, Sengupta S, McCue B, Kinter M, Sen GC, Sen I. Calmodulin binds to the cytoplasmic domain of angiotensin-converting enzyme and regulates its phosphorylation and cleavage secretion. The Journal of Biological Chemistry. 280: 33847-55. PMID 16096279 DOI: 10.1074/Jbc.M501718200  0.345
2005 Terenzi F, Pal S, Sen GC. Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54. Virology. 340: 116-24. PMID 16023166 DOI: 10.1016/J.Virol.2005.06.011  0.507
2005 Sarkar SN, Pandey M, Sen GC. Assays for the interferon-induced enzyme 2',5' oligoadenylate synthetases. Methods in Molecular Medicine. 116: 81-101. PMID 16000856 DOI: 10.1385/1-59259-939-7:081  0.434
2005 Sarkar SN, Kessler SP, Rowe TM, Pandey M, Ghosh A, Elco CP, Hartmann R, Pal S, Sen GC. Natural mutations in a 2'-5' oligoadenylate synthetase transgene revealed residues essential for enzyme activity. Biochemistry. 44: 6837-43. PMID 15865429 DOI: 10.1021/Bi0502893  0.395
2005 Elco CP, Guenther JM, Williams BR, Sen GC. Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3. Journal of Virology. 79: 3920-9. PMID 15767394 DOI: 10.1128/Jvi.79.7.3920-3929.2005  0.436
2005 Sen GC, Sarkar SN. Transcriptional signaling by double-stranded RNA: role of TLR3. Cytokine & Growth Factor Reviews. 16: 1-14. PMID 15733829 DOI: 10.1016/J.Cytogfr.2005.01.006  0.451
2005 Hui DJ, Terenzi F, Merrick WC, Sen GC. Mouse p56 blocks a distinct function of eukaryotic initiation factor 3 in translation initiation Journal of Biological Chemistry. 280: 3433-3440. PMID 15561726 DOI: 10.1074/Jbc.M406700200  0.732
2005 Sarkar SN, Peters GA, Sen GC. Genes modulated by interferons and double-stranded RNA Modulation of Host Gene Expression and Innate Immunity by Viruses. 35-63. DOI: 10.1007/1-4020-3242-0_3  0.347
2004 Sarkar SN, Peters KL, Elco CP, Sakamoto S, Pal S, Sen GC. Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling. Nature Structural & Molecular Biology. 11: 1060-7. PMID 15502848 DOI: 10.1038/Nsmb847  0.416
2004 Sarkar SN, Sen GC. Novel functions of proteins encoded by viral stress-inducible genes. Pharmacology & Therapeutics. 103: 245-59. PMID 15464592 DOI: 10.1016/J.Pharmthera.2004.07.007  0.471
2004 Jiang Z, Mak TW, Sen G, Li X. Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. Proceedings of the National Academy of Sciences of the United States of America. 101: 3533-8. PMID 14982987 DOI: 10.1073/Pnas.0308496101  0.376
2004 Chawla-Sarkar M, Lindner DJ, Liu YF, Williams BR, Sen GC, Silverman RH, Borden EC. Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 8: 237-49. PMID 12766484 DOI: 10.1023/A:1023668705040  0.417
2003 Li S, Sen GC. PACT-mediated enhancement of reporter gene expression at the translational level. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 23: 689-97. PMID 14769145 DOI: 10.1089/107999003772084806  0.623
2003 Hartmann R, Justesen J, Sarkar SN, Sen GC, Yee VC. Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase. Molecular Cell. 12: 1173-85. PMID 14636576 DOI: 10.1016/S1097-2765(03)00433-7  0.409
2003 Hui DJ, Bhasker CR, Merrick WC, Sen GC. Viral stress-inducible protein p56 inhibits translation by blocking the interaction of eIF3 with the ternary complex eIF2·GTP· Met-tRNAi Journal of Biological Chemistry. 278: 39477-39482. PMID 12885778 DOI: 10.1074/Jbc.M305038200  0.733
2003 Williams BR, Sen GC. Immunology. A viral on/off switch for interferon. Science (New York, N.Y.). 300: 1100-1. PMID 12750505 DOI: 10.1126/Science.1085277  0.381
2003 Wang C, Pflugheber J, Sumpter R, Sodora DL, Hui D, Sen GC, Gale M. Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication. Journal of Virology. 77: 3898-912. PMID 12634350 DOI: 10.1128/Jvi.77.7.3898-3912.2003  0.712
2003 Sarkar SN, Smith HL, Rowe TM, Sen GC. Double-stranded RNA signaling by Toll-like receptor 3 requires specific tyrosine residues in its cytoplasmic domain. The Journal of Biological Chemistry. 278: 4393-6. PMID 12509442 DOI: 10.1074/Jbc.C200655200  0.475
2002 Peters GA, Khoo D, Mohr I, Sen GC. Inhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein. Journal of Virology. 76: 11054-64. PMID 12368348 DOI: 10.1128/Jvi.76.21.11054-11064.2002  0.432
2002 Sarkar SN, Pal S, Sen GC. Crisscross enzymatic reaction between the two molecules in the active dimeric P69 form of the 2'-5' oligodenylate synthetase. The Journal of Biological Chemistry. 277: 44760-4. PMID 12223486 DOI: 10.1074/Jbc.M207126200  0.367
2002 Sarkar SN, Miyagi M, Crabb JW, Sen GC. Identification of the substrate-binding sites of 2'-5'-oligoadenylate synthetase. The Journal of Biological Chemistry. 277: 24321-30. PMID 11986302 DOI: 10.1074/Jbc.M110202200  0.307
2002 Peters KL, Smith HL, Stark GR, Sen GC. IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America. 99: 6322-7. PMID 11972054 DOI: 10.1073/Pnas.092133199  0.456
2002 Gomos JB, Rowe TM, Sarkar SN, Kessler SP, Sen GC. The proapoptotic 9-2 isozyme of 2-5 (A) synthetase cannot substitute for the sperm functions of the proapoptotic protein, Bax. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 199-206. PMID 11911802 DOI: 10.1089/107999002753536167  0.318
2002 Gorbacheva VY, Lindner D, Sen GC, Vestal DJ. The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation. The Journal of Biological Chemistry. 277: 6080-7. PMID 11726669 DOI: 10.1074/Jbc.M110542200  0.392
2001 Rowe TM, Sen GC. Organizations and promoter analyses of the human and the mouse genes for PACT, the protein-activator of the interferon-induced protein kinase, PKR Gene. 273: 215-225. PMID 11595168 DOI: 10.1016/S0378-1119(01)00588-1  0.364
2001 Sen GC. Viruses and interferons Annual Review of Microbiology. 55: 255-281. PMID 11544356 DOI: 10.1146/Annurev.Micro.55.1.255  0.487
2001 Geiss G, Jin G, Guo J, Bumgarner R, Katze MG, Sen GC. A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling. The Journal of Biological Chemistry. 276: 30178-82. PMID 11487589 DOI: 10.1074/Jbc.C100137200  0.607
2001 Ghosh A, Sarkar SN, Rowe TM, Sen GC. A Specific Isozyme of 2′-5′ Oligoadenylate Synthetase is a Dual Function Proapoptotic Protein of the Bcl-2 Family Journal of Biological Chemistry. 276: 25447-25455. PMID 11323417 DOI: 10.1074/Jbc.M100496200  0.418
2001 Peters GA, Hartmann R, Qin J, Sen GC. Modular structure of PACT: Distinct domains for binding and activating PKR Molecular and Cellular Biology. 21: 1908-1920. PMID 11238927 DOI: 10.1128/Mcb.21.6.1908-1920.2001  0.354
2000 Guo J, Hui DJ, Merrick WC, Sen GC. A new pathway of translational regulation mediated by eukaryotic initiation factor 3 Embo Journal. 19: 6891-6899. PMID 11118224 DOI: 10.1093/Emboj/19.24.6891  0.771
2000 Vestal DJ, Gorbacheva VY, Sen GC. Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: Implications for different functions? Journal of Interferon and Cytokine Research. 20: 991-1000. PMID 11096456 DOI: 10.1089/10799900050198435  0.354
2000 Sen GC. Novel functions of interferon-induced proteins Seminars in Cancer Biology. 10: 93-101. PMID 10936060 DOI: 10.1006/Scbi.2000.0312  0.441
2000 Kessler SP, Rowe TM, Gomos JB, Kessler PM, Sen GC. Physiological non-equivalence of the two isoforms of angiotensin-converting enzyme Journal of Biological Chemistry. 275: 26259-26264. PMID 10831599 DOI: 10.1074/Jbc.M004006200  0.314
2000 Guo J, Peters KL, Sen GC. Induction of the human protein P56 by interferon, double-stranded RNA, or virus infection. Virology. 267: 209-19. PMID 10662616 DOI: 10.1006/Viro.1999.0135  0.677
2000 Guo J, Sen GC. Characterization of the interaction between the interferon-induced protein P56 and the Int6 protein encoded by a locus of insertion of the mouse mammary tumor virus. Journal of Virology. 74: 1892-9. PMID 10644362 DOI: 10.1128/Jvi.74.4.1892-1899.2000  0.63
2000 Ghosh A, Sarkar SN, Sen GC. Cell growth regulatory and antiviral effects of the P69 isozyme of 2-5 (A) synthetase Virology. 266: 319-328. PMID 10639318 DOI: 10.1006/Viro.1999.0085  0.415
1999 Sarkar SN, Ghosh A, Wang HW, Sung SS, Sen GC. The nature of the catalytic domain of 2'-5'-oligoadenylate synthetases Journal of Biological Chemistry. 274: 25535-25542. PMID 10464285 DOI: 10.1074/Jbc.274.36.25535  0.343
1999 Patel RC, Vestal DJ, Xu Z, Bandyopadhyay S, Guo W, Erme SM, Williams BR, Sen GC. DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR. The Journal of Biological Chemistry. 274: 20432-7. PMID 10400669 DOI: 10.1074/Jbc.274.29.20432  0.346
1999 Floyd-Smith G, Wang Q, Sen GC. Transcriptional induction of the p69 isoform of 2',5'-oligoadenylate synthetase by interferon-β and interferon-γ involves three regulatory elements and interferon-stimulated gene factor 3 Experimental Cell Research. 246: 138-147. PMID 9882523 DOI: 10.1006/Excr.1998.4296  0.395
1999 Sarkar SN, Bandyopadhyay S, Ghosh A, Sen GC. Enzymatic characteristics of recombinant medium isozyme of 2'-5' oligoadenylate synthetase Journal of Biological Chemistry. 274: 1848-1855. PMID 9880569 DOI: 10.1074/Jbc.274.3.1848  0.436
1998 Patel RC, Sen GC. Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast Molecular and Cellular Biology. 18: 7009-7019. PMID 9819388 DOI: 10.1128/Mcb.18.12.7009  0.411
1998 Sarkar SN, Sen GC. Production, Purification, and Characterization of Recombinant 2′,5′-Oligoadenylate Synthetases Methods. 15: 233-242. PMID 9735308 DOI: 10.1006/Meth.1998.0627  0.425
1998 Leaman DW, Salvekar A, Patel R, Sen GC, Stark GR. A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes Proceedings of the National Academy of Sciences of the United States of America. 95: 9442-9447. PMID 9689099 DOI: 10.1073/Pnas.95.16.9442  0.467
1998 Patel RC, Sen GC. PACT, a protein activator of the interferon-induced protein kinase, PKR Embo Journal. 17: 4379-4390. PMID 9687506 DOI: 10.1093/Emboj/17.15.4379  0.491
1998 Bandyopadhyay S, Ghosh A, Sarkar SN, Sen GC. Production and purification of recombinant 2'-5' oligoadenylate synthetase and its mutants using the baculovirus system Biochemistry. 37: 3824-3830. PMID 9521702 DOI: 10.1021/Bi972848E  0.413
1998 Sadhukhan M, Sen GC, Ramchandran R, Sen I. The distal ectodomain of angiotensin-converting enzyme regulates its cleavage-secretion from the cell surface Proceedings of the National Academy of Sciences of the United States of America. 95: 138-143. PMID 9419342 DOI: 10.1073/Pnas.95.1.138  0.336
1997 Ghosh A, Sarkar SN, Guo W, Bandyopadhyay S, Sen GC. Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein Journal of Biological Chemistry. 272: 33220-33226. PMID 9407111 DOI: 10.1074/Jbc.272.52.33220  0.394
1997 Desai SY, Sen GC. Effects of varying lengths of double-stranded RNA on binding and activation of 2'-5'-oligoadenylate synthetase Journal of Interferon and Cytokine Research. 17: 531-536. PMID 9335430 DOI: 10.1089/Jir.1997.17.531  0.357
1997 Leonard GT, Sen GC. Restoration of interferon responses of adenovirus E1A-expressing HT1080 cell lines by overexpression of p48 protein. Journal of Virology. 71: 5095-101. PMID 9188575 DOI: 10.1128/Jvi.71.7.5095-5101.1997  0.445
1997 Ghosh A, Desai SY, Sarkar SN, Ramaraj P, Ghosh SK, Bandyopadhyay S, Sen GC. Effects of mutating specific residues present near the amino terminus of 2'-5'-oligoadenylate synthetase Journal of Biological Chemistry. 272: 15452-15458. PMID 9182577 DOI: 10.1074/Jbc.272.24.15452  0.37
1996 Leonard GT, Sen GC. Effects of adenovirus E1A protein on interferon-signaling. Virology. 224: 25-33. PMID 8862396 DOI: 10.1006/Viro.1996.0503  0.404
1996 Erickson RP, Kessler S, Kremling H, Sen GC. Species variation in the testicular angiotensin converting enzyme promoter studied in transgenic mice. Molecular Reproduction and Development. 44: 324-31. PMID 8858602 DOI: 10.1002/(Sici)1098-2795(199607)44:3<324::Aid-Mrd6>3.0.Co;2-O  0.316
1996 Patel RC, Stanton P, Sen GC. Specific mutations near the amino terminus of double-stranded RNA- dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties Journal of Biological Chemistry. 271: 25657-25663. PMID 8810342 DOI: 10.1074/Jbc.271.41.25657  0.436
1996 Sadhukhan R, Sen GC, Sen I. Synthesis and cleavage-secretion of enzymatically active rabbit angiotensin-converting enzyme in Pichia pastoris Journal of Biological Chemistry. 271: 18310-18313. PMID 8702467 DOI: 10.1074/Jbc.271.31.18310  0.362
1995 Bandyopadhyay SK, Leonard GT, Bandyopadhyay T, Stark GR, Sen GC. Transcriptional induction by double-stranded RNA is mediated by interferon-stimulated response elements without activation of interferon-stimulated gene factor 3. The Journal of Biological Chemistry. 270: 19624-9. PMID 7642650 DOI: 10.1074/Jbc.270.33.19624  0.46
1995 Goraya TY, Kessler SP, Stanton P, Hanson RW, Sen GC. The cyclic AMP response elements of the genes for angiotensin converting enzyme and phosphoenolpyruvate carboxykinase (GTP) can mediate transcriptional activation by CREM tau and CREM alpha. The Journal of Biological Chemistry. 270: 19078-85. PMID 7642572 DOI: 10.1074/Jbc.270.32.19078  0.361
1995 Patel RC, Stanton P, Mcmillan NMJ, Williams BRG, Sen GC. The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 92: 8283-8287. PMID 7545299 DOI: 10.1073/Pnas.92.18.8283  0.444
1995 Desai SY, Patel RC, Sen GC, Malhotra P, Ghadge GD, Thimmapaya B. Activation of interferon-inducible 2′-5′ oligoadenylate synthetase by adenoviral VAI RNA Journal of Biological Chemistry. 270: 3454-3461. PMID 7531709 DOI: 10.1074/Jbc.270.7.3454  0.421
1994 Kasturi S, Jabbar MA, Sen GC, Sen I. Role of glycosylation in the biosynthesis and activity of rabbit testicular angiotensin-converting enzyme Biochemistry. 33: 6228-6234. PMID 8193137 DOI: 10.1021/Bi00186A024  0.365
1994 Goraya TY, Kessler SP, Kumar RS, Douglas J, Sen GC. Identification of positive and negative transcriptional regulatory elements of the rabbit angiotensin-converting enzyme gene Nucleic Acids Research. 22: 1194-1201. PMID 8165133 DOI: 10.1093/Nar/22.7.1194  0.319
1994 Wu C, Ohmori Y, Bandyopadhyay S, Sen G, Hamilton TA. Interferon-stimulated response element and NFκB sites cooperate to regulate double-stranded RNA-induced transcription of the IP-10 gene Journal of Interferon Research. 14: 357-363. PMID 7897255 DOI: 10.1089/Jir.1994.14.357  0.424
1994 Maitra RK, McMillan NA, Desai S, McSwiggen J, Hovanessian AG, Sen G, Williams BR, Silverman RH. HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes. Virology. 204: 823-7. PMID 7524241 DOI: 10.1006/Viro.1994.1601  0.377
1994 Patel RC, Stanton P, Sen GC. Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin Journal of Biological Chemistry. 269: 18593-18598. PMID 7518438  0.327
1993 Kalvakolanu DVR, Sen GC. Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-κB in mouse embryonal carcinoma cells Proceedings of the National Academy of Sciences of the United States of America. 90: 3167-3171. PMID 8475056 DOI: 10.1073/Pnas.90.8.3167  0.398
1993 Clemens MJ, Hershey JW, Hovanessian AC, Jacobs BC, Katze MG, Kaufman RJ, Lengyel P, Samuel CE, Sen GC, Williams BR. PKR: proposed nomenclature for the RNA-dependent protein kinase induced by interferon. Journal of Interferon Research. 13: 241. PMID 7690057 DOI: 10.1089/Jir.1993.13.241  0.398
1993 Sen GC, Ransohoff RM. Interferon-induced antiviral actions and their regulation Advances in Virus Research. 42: 57-102. PMID 7679242 DOI: 10.1016/S0065-3527(08)60083-4  0.416
1992 Bandyopadhyay SK, Sen GC. Role of protein phosphorylation in activation of interferon-stimulated gene factors Journal of Biological Chemistry. 267: 6389-6395. PMID 1556141  0.347
1992 Patel RC, Sen GC. Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase Journal of Biological Chemistry. 267: 7671-7676. PMID 1373135  0.342
1992 Patel RC, Sen GC. Construction and expression of an enzymatically active human-mouse chimeric double-stranded RNA-dependent protein kinase Journal of Interferon Research. 12: 389-393. PMID 1358989 DOI: 10.1089/Jir.1992.12.389  0.43
1992 Kalvakolanu DV, Liu J, Hanson RW, Harter ML, Sen GC. Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells. The Journal of Biological Chemistry. 267: 2530-6. PMID 1310318  0.306
1991 Kalvakolanu DVR, Bandyopadhyay SK, Harter ML, Sen GC. Inhibition of interferon-inducible gene expression by adenovirus E1A proteins: Block in transcriptional complex formation Proceedings of the National Academy of Sciences of the United States of America. 88: 7459-7463. PMID 1652751 DOI: 10.1073/Pnas.88.17.7459  0.472
1990 Bandyopadhyay SK, Kalvakolanu DVR, Sen GC. Gene induction by interferons: Functional complementation between trans-acting factors induced by alpha interferon and gamma interferon Molecular and Cellular Biology. 10: 5055-5063. PMID 2118988 DOI: 10.1128/Mcb.10.10.5055  0.423
1990 Margolis-Nunno H, Rubin BY, Anderson SL, Lunn RM, Roy SN, Dizik M, Sen GC. Isolation of cDNA clones for the interferon-induced 67,000-dalton protein: direct induction of a family of mRNAs by human interferon-alpha and interferon-gamma. Journal of Interferon Research. 10: 309-19. PMID 1696608 DOI: 10.1089/Jir.1990.10.309  0.381
1989 Kumar R, Sen GC. Interferon-mediated inhibition of retroviral infection: use of a defective retrovirus carrying a drug-resistance gene Virus Research. 13: 295-302. PMID 2554610 DOI: 10.1016/0168-1702(89)90075-0  0.332
1988 Kumar R, Choubey D, Lengyel P, Sen GC. Studies on the role of the 2'-5'-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication. Journal of Virology. 62: 3175-81. PMID 2841470  0.315
1987 Belkowski LS, Sen GC. Inhibition of vesicular stomatitis viral mRNA synthesis by interferons Journal of Virology. 61: 653-660. PMID 3027394  0.332
1983 Sen GC, Pinter A. Interferon-mediated inhibition of production of Gazdar murine sarcoma virus, a retrovirus lacking env proteins and containing an uncleaved gag precursor Virology. 126: 403-407. PMID 6302994 DOI: 10.1016/0042-6822(83)90492-0  0.321
1983 Sen GC, Herz RE, Rubin BY. Antiviral, anticellular and enzyme-inducing activities of interferons in RD-114 cells Journal of General Virology. 64: 2213-2220. PMID 6194249  0.327
1981 Sen GC, Racevskis J, Sarkar NH. Synthesis of murine mammary tumor viral proteins in vitro Journal of Virology. 37: 963-975. PMID 6262538  0.306
1979 Sen GC, Smith SW, Marcus SL, Sarkar NH. Identification of the messenger RNAs coding for the gag and env gene products of the murine mammary tumor virus Proceedings of the National Academy of Sciences of the United States of America. 76: 1736-1740. PMID 221904 DOI: 10.1073/Pnas.76.4.1736  0.401
1978 Farrell PJ, Sen GC, Dubois MF, Ratner L, Slattery E, Lengyel P. Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America. 75: 5893-7. PMID 282611 DOI: 10.1073/Pnas.75.12.5893  0.33
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