| Year |
Citation |
Score |
| 2023 |
Chitsike L, Bertucci A, Vazquez M, Lee S, Unternaehrer JJ, Duerksen-Hughes PJ. GA-OH enhances the cytotoxicity of photon and proton radiation in HPV HNSCC cells. Frontiers in Oncology. 13: 1070485. PMID 36845698 DOI: 10.3389/fonc.2023.1070485 |
0.406 |
|
| 2022 |
Katerji M, Bertucci A, Filippov V, Vazquez M, Chen X, Duerksen-Hughes PJ. Proton-induced DNA damage promotes integration of foreign plasmid DNA into human genome. Frontiers in Oncology. 12: 928545. PMID 36119491 DOI: 10.3389/fonc.2022.928545 |
0.325 |
|
| 2021 |
Chitsike L, Duerksen-Hughes PJ. PPI Modulators of E6 as Potential Targeted Therapeutics for Cervical Cancer: Progress and Challenges in Targeting E6. Molecules (Basel, Switzerland). 26. PMID 34070144 DOI: 10.3390/molecules26103004 |
0.375 |
|
| 2021 |
Chitsike L, Yuan CH, Roy A, Boyle K, Duerksen-Hughes PJ. A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV head and neck squamous cell carcinomas. Oncotarget. 12: 549-561. PMID 33796223 DOI: 10.18632/oncotarget.27908 |
0.739 |
|
| 2020 |
Katerji M, Filippova M, Wongworawat YC, Siddighi S, Bashkirova S, Duerksen-Hughes PJ. Oxidative stress markers in patient-derived non-cancerous cervical tissues and cells. Scientific Reports. 10: 19044. PMID 33149215 DOI: 10.1038/s41598-020-76159-2 |
0.363 |
|
| 2020 |
Chitsike L, Duerksen-Hughes P. The Potential of Immune Checkpoint Blockade in Cervical Cancer: Can Combinatorial Regimens Maximize Response? A Review of the Literature. Current Treatment Options in Oncology. 21: 95. PMID 33025260 DOI: 10.1007/s11864-020-00790-4 |
0.319 |
|
| 2019 |
Mirshahidi S, de Necochea-Campion R, Moretta A, Williams NL, Reeves ME, Otoukesh S, Mirshahidi HR, Khosrowpour S, Duerksen-Hughes P, Zuckerman LM. Inhibitory Effects of Indomethacin in Human MNNG/HOS Osteosarcoma Cell Line . Cancer Investigation. 1-29. PMID 31770037 DOI: 10.1080/07357907.2019.1698592 |
0.411 |
|
| 2019 |
Katerji M, Filippova M, Duerksen-Hughes P. Approaches and Methods to Measure Oxidative Stress in Clinical Samples: Research Applications in the Cancer Field. Oxidative Medicine and Cellular Longevity. 2019: 1279250. PMID 30992736 DOI: 10.1155/2019/1279250 |
0.302 |
|
| 2019 |
Hu J, Mirshahidi S, Simental A, Lee SC, De Andrade Filho PA, Peterson NR, Duerksen-Hughes P, Yuan X. Cancer stem cell self-renewal as a therapeutic target in human oral cancer. Oncogene. PMID 30936460 DOI: 10.1038/S41388-019-0800-Z |
0.343 |
|
| 2017 |
Mirshahidi S, Simental A, Lee S, De Andrade Filho PA, Peterson NR, Cao W, Necochea-Campion R, Yang H, Duerksen-Hughes P, Yuan X. Subpopulations of cancer stem cells found in papillary thyroid carcinoma. Experimental Cell Research. PMID 29274322 DOI: 10.1016/J.Yexcr.2017.12.017 |
0.313 |
|
| 2017 |
Simental A, Lee S, Filho PADA, Peterson NR, Mirshahidi S, Duerksen-Hughes P, Yuan X. Abstract 60: Characterization of papillary thyroid carcinoma primary cell culture derived cancer stem-like cells Clinical Cancer Research. 23: 60-60. DOI: 10.1158/1557-3265.Aacrahns17-60 |
0.332 |
|
| 2016 |
Evans W, Filippova M, Filippov V, Bashkirova S, Zhang G, Reeves ME, Duerksen-Hughes P. Overexpression of HPV16 E6* Alters β-Integrin and Mitochondrial Dysfunction Pathways in Cervical Cancer Cells. Cancer Genomics & Proteomics. 13: 259-273. PMID 27365376 |
0.523 |
|
| 2016 |
Chen Wongworawat Y, Filippova M, Williams VM, Filippov V, Duerksen-Hughes PJ. Chronic oxidative stress increases the integration frequency of foreign DNA and human papillomavirus 16 in human keratinocytes. American Journal of Cancer Research. 6: 764-80. PMID 27186429 |
0.751 |
|
| 2016 |
Yuan CH, Filippova M, Krstenansky JL, Duerksen-Hughes PJ. Flavonol and imidazole derivatives block HPV16 E6 activities and reactivate apoptotic pathways in HPV(+) cells. Cell Death & Disease. 7: 2060. PMID 26794656 DOI: 10.1038/cddis.2015.391 |
0.755 |
|
| 2016 |
Evans W, Filippova M, Filippov V, Bashkirova S, Zhang G, Reeves ME, Duerksen-Hughes P. Overexpression of HPV16 E6∗ alters β-integrin and mitochondrial dysfunction pathways in cervical cancer cells Cancer Genomics and Proteomics. 13: 259-274. |
0.455 |
|
| 2015 |
Whang SN, Filippova M, Duerksen-Hughes P. Recent Progress in Therapeutic Treatments and Screening Strategies for the Prevention and Treatment of HPV-Associated Head and Neck Cancer. Viruses. 7: 5040-65. PMID 26393639 DOI: 10.3390/V7092860 |
0.493 |
|
| 2015 |
Tolen JA, Duerksen-Hughes P, Lau K, Chan PJ. Selenium Attenuates HPV-18 Associated Apoptosis in Embryo-Derived Trophoblastic Cells but Not Inner Cell Mass In Vitro. International Journal of Reproductive Medicine. 2015: 562567. PMID 26345191 DOI: 10.1155/2015/562567 |
0.45 |
|
| 2015 |
Carr KR, Ioffe YJ, Filippova M, Duerksen-Hughes P, Chan PJ. Combined ultrasound-curcumin treatment of human cervical cancer cells. European Journal of Obstetrics, Gynecology, and Reproductive Biology. 193: 96-101. PMID 26262768 DOI: 10.1016/J.Ejogrb.2015.07.011 |
0.52 |
|
| 2015 |
Evans W, Filippova M, Aragon R, Filippov V, Reeves ME, Duerksen-Hughes P. Abstract 1828: Proteomic analysis of the effect of E6 star expression on cellular pathways in HPV positive SiHa and HPV negative C33A cervical carcinoma cells Cancer Research. 75: 1828-1828. DOI: 10.1158/1538-7445.Am2015-1828 |
0.638 |
|
| 2014 |
Filippova M, Filippov V, Williams VM, Zhang K, Kokoza A, Bashkirova S, Duerksen-Hughes P. Cellular levels of oxidative stress affect the response of cervical cancer cells to chemotherapeutic agents. Biomed Research International. 2014: 574659. PMID 25478571 DOI: 10.1155/2014/574659 |
0.707 |
|
| 2014 |
Chen Y, Williams V, Filippova M, Filippov V, Duerksen-Hughes P. Viral carcinogenesis: factors inducing DNA damage and virus integration. Cancers. 6: 2155-86. PMID 25340830 DOI: 10.3390/Cancers6042155 |
0.688 |
|
| 2014 |
Gao X, Kong L, Lu X, Zhang G, Chi L, Jiang Y, Wu Y, Yan C, Duerksen-Hughes P, Zhu X, Yang J. Paraspeckle protein 1 (PSPC1) is involved in the cisplatin induced DNA damage response--role in G1/S checkpoint. Plos One. 9: e97174. PMID 24819514 DOI: 10.1371/Journal.Pone.0097174 |
0.37 |
|
| 2014 |
Hsu HW, de Necochea-Campion R, Williams V, Duerksen-Hughes PJ, Simental AA, Ferris RL, Chen CS, Mirshahidi S. Linifanib (ABT-869), enhances cytotoxicity with poly (ADP-ribose) polymerase inhibitor, veliparib (ABT-888), in head and neck carcinoma cells. Oral Oncology. 50: 662-9. PMID 24735547 DOI: 10.1016/J.Oraloncology.2014.03.006 |
0.656 |
|
| 2014 |
Williams VM, Filippova M, Filippov V, Payne KJ, Duerksen-Hughes P. Human papillomavirus type 16 E6* induces oxidative stress and DNA damage. Journal of Virology. 88: 6751-61. PMID 24696478 DOI: 10.1128/Jvi.03355-13 |
0.806 |
|
| 2014 |
Filippova M, Evans W, Aragon R, Filippov V, Williams VM, Hong L, Reeves ME, Duerksen-Hughes P. The small splice variant of HPV16 E6, E6, reduces tumor formation in cervical carcinoma xenografts. Virology. 450: 153-64. PMID 24503078 DOI: 10.1016/J.Virol.2013.12.011 |
0.81 |
|
| 2014 |
Evans W, Filippova M, Aragon R, Filippov V, Reeves M, Duerksen-Hughes P. Abstract 3175: The splice variant of the human papillomavirus 16 E6 protein, E6*, displays anti-tumor propertiesin vivo Cancer Research. 74: 3175-3175. DOI: 10.1158/1538-7445.Am2014-3175 |
0.645 |
|
| 2014 |
Williams VM, Duerksen-Hughes P. Stress, The immune system and cancer Stress and Developmental Programming of Health and Disease: Beyond Phenomenology. 602-631. |
0.6 |
|
| 2012 |
Yuan CH, Filippova M, Duerksen-Hughes P. Modulation of apoptotic pathways by human papillomaviruses (HPV): mechanisms and implications for therapy. Viruses. 4: 3831-50. PMID 23250450 DOI: 10.3390/V4123831 |
0.721 |
|
| 2012 |
Jiang Y, Zhang XY, Sun L, Zhang GL, Duerksen-Hughes P, Zhu XQ, Yang J. Methyl methanesulfonate induces apoptosis in p53-deficient H1299 and Hep3B cells through a caspase 2- and mitochondria-associated pathway. Environmental Toxicology and Pharmacology. 34: 694-704. PMID 23117069 DOI: 10.1016/J.Etap.2012.09.019 |
0.382 |
|
| 2012 |
Yuan CH, Filippova M, Tungteakkhun SS, Duerksen-Hughes PJ, Krstenansky JL. Small molecule inhibitors of the HPV16-E6 interaction with caspase 8. Bioorganic & Medicinal Chemistry Letters. 22: 2125-9. PMID 22300659 DOI: 10.1016/J.Bmcl.2011.12.145 |
0.821 |
|
| 2011 |
Williams VM, Filippova M, Soto U, Duerksen-Hughes PJ. HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress. Future Virology. 6: 45-57. PMID 21318095 DOI: 10.2217/Fvl.10.73 |
0.715 |
|
| 2010 |
Tungteakkhun SS, Filippova M, Fodor N, Duerksen-Hughes PJ. The full-length isoform of human papillomavirus 16 E6 and its splice variant E6* bind to different sites on the procaspase 8 death effector domain. Journal of Virology. 84: 1453-63. PMID 19906919 DOI: 10.1128/Jvi.01331-09 |
0.809 |
|
| 2009 |
Filippova M, Filippov VA, Kagoda M, Garnett T, Fodor N, Duerksen-Hughes PJ. Complexes of human papillomavirus type 16 E6 proteins form pseudo-death-inducing signaling complex structures during tumor necrosis factor-mediated apoptosis. Journal of Virology. 83: 210-27. PMID 18842714 DOI: 10.1128/Jvi.01365-08 |
0.832 |
|
| 2008 |
Tungteakkhun SS, Filippova M, Neidigh JW, Fodor N, Duerksen-Hughes PJ. The interaction between human papillomavirus type 16 and FADD is mediated by a novel E6 binding domain. Journal of Virology. 82: 9600-14. PMID 18632871 DOI: 10.1128/Jvi.00538-08 |
0.813 |
|
| 2008 |
Filippov V, Schmidt EL, Filippova M, Duerksen-Hughes PJ. Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes. Gene. 420: 34-41. PMID 18571879 DOI: 10.1016/J.Gene.2008.05.008 |
0.573 |
|
| 2008 |
Tungteakkhun SS, Duerksen-Hughes PJ. Cellular binding partners of the human papillomavirus E6 protein. Archives of Virology. 153: 397-408. PMID 18172569 DOI: 10.1007/S00705-007-0022-5 |
0.838 |
|
| 2007 |
Garnett TO, Filippova M, Duerksen-Hughes PJ. Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells. Apoptosis : An International Journal On Programmed Cell Death. 12: 1299-315. PMID 17431792 DOI: 10.1007/S10495-007-0058-8 |
0.786 |
|
| 2007 |
Filippova M, Johnson MM, Bautista M, Filippov V, Fodor N, Tungteakkhun SS, Williams K, Duerksen-Hughes PJ. The large and small isoforms of human papillomavirus type 16 E6 bind to and differentially affect procaspase 8 stability and activity. Journal of Virology. 81: 4116-29. PMID 17267478 DOI: 10.1128/Jvi.01924-06 |
0.83 |
|
| 2006 |
Garnett TO, Duerksen-Hughes PJ. Modulation of apoptosis by human papillomavirus (HPV) oncoproteins. Archives of Virology. 151: 2321-35. PMID 16862386 DOI: 10.1007/S00705-006-0821-0 |
0.825 |
|
| 2006 |
Garnett TO, Filippova M, Duerksen-Hughes PJ. Accelerated degradation of FADD and procaspase 8 in cells expressing human papilloma virus 16 E6 impairs TRAIL-mediated apoptosis. Cell Death and Differentiation. 13: 1915-26. PMID 16528386 DOI: 10.1038/Sj.Cdd.4401886 |
0.815 |
|
| 2005 |
Filippova M, Brown-Bryan TA, Casiano CA, Duerksen-Hughes PJ. The human papillomavirus 16 E6 protein can either protect or further sensitize cells to TNF: effect of dose. Cell Death and Differentiation. 12: 1622-35. PMID 15933739 DOI: 10.1038/Sj.Cdd.4401678 |
0.547 |
|
| 2004 |
Filippova M, Parkhurst L, Duerksen-Hughes PJ. The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis. The Journal of Biological Chemistry. 279: 25729-44. PMID 15073179 DOI: 10.1074/jbc.M401172200 |
0.615 |
|
| 2002 |
Filippova M, Song H, Connolly JL, Dermody TS, Duerksen-Hughes PJ. The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis. The Journal of Biological Chemistry. 277: 21730-9. PMID 11934887 DOI: 10.1074/jbc.M200113200 |
0.572 |
|
| 1999 |
Duerksen-Hughes PJ, Yang J, Schwartz SB. HPV 16 E6 blocks TNF-mediated apoptosis in mouse fibroblast LM cells Virology. 264: 55-65. PMID 10544129 DOI: 10.1006/viro.1999.9977 |
0.506 |
|
| 1998 |
Yang J, Duerksen-Hughes P. A new approach to identifying genotoxic carcinogens: P53 induction as an indicator of genotoxic damage Carcinogenesis. 19: 1117-1125. PMID 9667752 DOI: 10.1093/Carcin/19.6.1117 |
0.32 |
|
| 1992 |
Duerksen-Hughes PJ, Day DB, Laster SM, Zachariades NA, Aquino L, Gooding LR. Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages Journal of Immunology. 149: 2114-2122. PMID 1325525 |
0.314 |
|
| 1991 |
Gooding LR, Ranheim TS, Tollefson AE, Aquino L, Duerksen-Hughes P, Horton TM, Wold WS. The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor. Journal of Virology. 65: 4114-23. PMID 1830111 DOI: 10.1128/Jvi.65.8.4114-4123.1991 |
0.321 |
|
| 1991 |
Gooding LR, Aquino L, Duerksen-Hughes PJ, Day D, Horton TM, Yei S, Wold WSM. The E1B 19,000-Molecular-Weight Protein of Group C Adenoviruses Prevents Tumor Necrosis Factor Cytolysis of Human Cells but Not of Mouse Cells Journal of Virology. 65: 3083-3094. PMID 1827845 DOI: 10.1128/Jvi.65.6.3083-3094.1991 |
0.303 |
|
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