| Year |
Citation |
Score |
| 2009 |
Nakashima Y, Nii H, Janowiak BE, Griffith OW, Hibi T. Crystallization and preliminary crystallographic analysis of bifunctional -glutamylcysteine synthetase-glutatione synthetase from Streptococcus agalactiae Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 678-680. PMID 19574637 DOI: 10.1107/S1744309109018636 |
0.64 |
|
| 2006 |
Janowiak BE, Hayward MA, Peterson FC, Volkman BF, Griffith OW. γ-glutamylcysteine synthetase-glutathione synthetase: Domain structure and identification of residues important in substrate and glutathione binding Biochemistry. 45: 10461-10473. PMID 16939198 DOI: 10.1021/Bi052483V |
0.664 |
|
| 2005 |
Nilakantan V, Halligan NL, Nguyen TK, Hilton G, Khanna AK, Roza AM, Johnson CP, Adams MB, Griffith OW, Pieper GM. Post-translational modification of manganese superoxide dismutase in acutely rejecting cardiac transplants: role of inducible nitric oxide synthase. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 24: 1591-9. PMID 16210135 DOI: 10.1016/J.Healun.2005.01.009 |
0.353 |
|
| 2005 |
Janowiak BE, Griffith OW. Glutathione synthesis in Streptococcus agalactiae: One protein accounts for γ-glutamylcysteine synthetase and glutathione synthetase activities Journal of Biological Chemistry. 280: 11829-11839. PMID 15642737 DOI: 10.1074/Jbc.M414326200 |
0.69 |
|
| 2004 |
Pieper GM, Nilakantan V, Hilton G, Zhou X, Khanna AK, Halligan NLN, Felix CC, Kampalath B, Griffith OW, Hayward MA, Roza AM, Adams MB. Variable efficacy of N6-(1-iminoethyl)-L-lysine in acute cardiac transplant rejection American Journal of Physiology - Heart and Circulatory Physiology. 286: H525-H534. PMID 14715498 DOI: 10.1152/Ajpheart.00356.2003 |
0.361 |
|
| 2004 |
Brenot A, King KY, Janowiak B, Griffith O, Caparon MG. Contribution of Glutathione Peroxidase to the Virulence of Streptococcus pyogenes Infection and Immunity. 72: 408-413. PMID 14688122 DOI: 10.1128/Iai.72.1.408-413.2004 |
0.659 |
|
| 2003 |
Bretscher LE, Li H, Poulos TL, Griffith OW. Structural Characterization and Kinetics of Nitric-oxide Synthase Inhibition by Novel N5-(Iminoalkyl)- and N 5-(Iminoalkenyl)-ornithines Journal of Biological Chemistry. 278: 46789-46797. PMID 12960153 DOI: 10.1074/Jbc.M306787200 |
0.315 |
|
| 2002 |
Kelly BS, Antholine WE, Griffith OW. Escherichia coli γ-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding Journal of Biological Chemistry. 277: 50-58. PMID 11675389 DOI: 10.1074/Jbc.M107961200 |
0.381 |
|
| 2001 |
Raman CS, Li H, Martásek P, Babu BR, Griffith OW, Masters BSS, Poulos TL. Implications for Isoform-selective Inhibitor Design Derived from the Binding Mode of Bulky Isothioureas to the Heme Domain of Endothelial Nitric-oxide Synthase Journal of Biological Chemistry. 276: 26486-26491. PMID 11331290 DOI: 10.1074/Jbc.M102255200 |
0.386 |
|
| 2000 |
Shi Y, Pritchard KA, Holman P, Rafiee P, Griffith OW, Kalyanaraman B, Baker JE. Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. Free Radical Biology & Medicine. 29: 695-703. PMID 11053770 DOI: 10.1016/S0891-5849(00)00364-6 |
0.316 |
|
| 1999 |
Griffith OW. Biologic and pharmacologic regulation of mammalian glutathione synthesis Free Radical Biology and Medicine. 27: 922-935. PMID 10569625 DOI: 10.1016/S0891-5849(99)00176-8 |
0.465 |
|
| 1999 |
Babu BR, Frey C, Griffith OW. L-arginine binding to nitric-oxide synthase. The role of H-bonds to the nonreactive guanidinium nitrogens Journal of Biological Chemistry. 274: 25218-25226. PMID 10464242 DOI: 10.1074/Jbc.274.36.25218 |
0.414 |
|
| 1999 |
Baker JE, Holman P, Kalyanaraman B, Griffith OW, Pritchard KA. Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production. Annals of the New York Academy of Sciences. 874: 236-53. PMID 10415535 DOI: 10.1111/J.1749-6632.1999.Tb09239.X |
0.356 |
|
| 1999 |
Griffith OW, Mulcahy RT. The enzymes of glutathione synthesis: γ-glutamylcysteine synthetase Advances in Enzymology and Related Areas of Molecular Biology. 73: 209-267. PMID 10218110 DOI: 10.1002/9780470123195.Ch7 |
0.406 |
|
| 1998 |
Babu BR, Griffith OW. Design of isoform-selective inhibitors of nitric oxide synthase Current Opinion in Chemical Biology. 2: 491-500. PMID 9736922 DOI: 10.1016/S1367-5931(98)80125-7 |
0.425 |
|
| 1998 |
Misra I, Griffith OW. Expression and purification of human γ-glutamylcysteine synthetase Protein Expression and Purification. 13: 268-276. PMID 9675072 DOI: 10.1006/Prep.1998.0897 |
0.448 |
|
| 1998 |
Babu BR, Griffith OW. N5-(1-imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase Journal of Biological Chemistry. 273: 8882-8889. PMID 9535869 DOI: 10.1074/Jbc.273.15.8882 |
0.431 |
|
| 1997 |
Griffith OW, Kilbourn RG. Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy Advances in Enzyme Regulation. 37: 171-194. PMID 9381971 DOI: 10.1016/S0065-2571(96)00008-8 |
0.374 |
|
| 1997 |
McDonald KK, Rouhani R, Handlogten ME, Block ER, Griffith OW, Allison RD, Kilberg MS. Inhibition of endothelial cell amino acid transport System y+ by arginine analogs that inhibit nitric oxide synthase Biochimica Et Biophysica Acta - Biomembranes. 1324: 133-141. PMID 9059506 DOI: 10.1016/S0005-2736(96)00226-X |
0.412 |
|
| 1997 |
Moynihan K, Elion GB, Pegram C, Reist CJ, Wellner D, Bigner DD, Griffith OW, Friedman HS. L-amino acid oxidase (LOX) modulation of melphalan activity against intracranial glioma. Cancer Chemotherapy and Pharmacology. 39: 179-86. PMID 8996517 DOI: 10.1007/S002800050557 |
0.321 |
|
| 1996 |
Griffith OW, Kilbourn RG. Nitric oxide synthase inhibitors: Amino acids Methods in Enzymology. 268: 375-392. PMID 8782604 DOI: 10.1016/S0076-6879(96)68040-9 |
0.365 |
|
| 1995 |
Kilbourn RG, Fonseca GA, Griffith OW, Ewer M, Price K, Striegel A, Jones E, Logothetis CJ. N(G)-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension Critical Care Medicine. 23: 1018-1024. PMID 7774211 DOI: 10.1097/00003246-199506000-00005 |
0.372 |
|
| 1995 |
Rich JN, Elion GB, Wellner D, Colvin OM, Groothuis DR, Hilton JH, Schlageter KE, Bigner DD, Griffith OW, Friedman HS. The effect of L-amino acid oxidase on activity of melphalan against an intracranial xenograft. Cancer Chemotherapy and Pharmacology. 36: 379-84. PMID 7634379 DOI: 10.1007/Bf00686186 |
0.339 |
|
| 1995 |
Joly GA, Narayanan K, Griffith OW, Kilbourn RG. Characterization of the effects of two new arginine/citrulline analogues on constitutive and inducible nitric oxide synthases in rat aorta British Journal of Pharmacology. 115: 491-497. PMID 7582462 DOI: 10.1111/J.1476-5381.1995.Tb16360.X |
0.372 |
|
| 1995 |
Griffith OW, Stuehr DJ. Nitric oxide synthases: Properties and catalytic mechanism Annual Review of Physiology. 57: 707-736. PMID 7539994 DOI: 10.1146/Annurev.Ph.57.030195.003423 |
0.336 |
|
| 1995 |
Narayanan K, Spack L, McMillan K, Kilbourn RG, Hayward MA, Masters BSS, Griffith OW. S-alkyl-L-thiocitrullines: Potent stereoselective inhibitors of nitric oxide synthase with strong pressor activity in vivo Journal of Biological Chemistry. 270: 11103-11110. PMID 7538112 DOI: 10.1074/Jbc.270.19.11103 |
0.448 |
|
| 1995 |
Salerno JC, Frey C, McMillan K, Williams RF, Masters BS, Griffith OW. Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase. The Journal of Biological Chemistry. 270: 27423-8. PMID 7499198 DOI: 10.1074/Jbc.270.46.27423 |
0.387 |
|
| 1994 |
Malaker K, Hurwitz SJ, Bump EA, Griffith OW, Lai LL, Riese N, Norman Coleman C. Pharmacodynamics of prolonged treatment with L,S-buthionine sulfoximine International Journal of Radiation Oncology, Biology, Physics. 29: 407-412. PMID 7910818 DOI: 10.1016/0360-3016(94)90299-2 |
0.336 |
|
| 1994 |
Frey C, Narayanan K, McMillan K, Spack L, Gross SS, Masters BS, Griffith OW. L-Thiocitrulline: A Stereospecific, Heme-binding Inhibitor of Nitric-oxide Synthases Journal of Biological Chemistry. 269: 26083-26091. PMID 7523401 |
0.341 |
|
| 1994 |
Narayanan K, Griffith OW. Synthesis of L-thiocitrulline, L-homothiocitrulline, and S-methyl-L-thiocitrulline: A new class of potent nitric oxide synthase inhibitors Journal of Medicinal Chemistry. 37: 885-887. PMID 7512141 DOI: 10.1021/Jm00033A004 |
0.422 |
|
| 1993 |
Feldman PL, Griffith OW, Hong H, Stuehr DJ. Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation. Journal of Medicinal Chemistry. 36: 491-6. PMID 7682617 DOI: 10.1021/Jm00056A009 |
0.446 |
|
| 1992 |
Kilbourn RG, Gross SS, Lodato RF, Adams J, Levi R, Miller LL, Lachman LB, Griffith OW. Inhibition of interleukin-1-α-induced nitric oxide synthase in vascular smooth muscle and full reversal of interleukin-1-α-induced hypotension by Nω-amino-L-arginine Journal of the National Cancer Institute. 84: 1008-1016. PMID 1376778 DOI: 10.1093/Jnci/84.13.1008 |
0.313 |
|
| 1992 |
Kilbourn RG, Griffith OW. Overproduction of nitric oxide in cytokine-mediated and septic shock. Journal of the National Cancer Institute. 84: 827-31. PMID 1375655 DOI: 10.1093/Jnci/84.11.827 |
0.335 |
|
| 1992 |
Bump E, Malaker K, Hurwitz S, Pierce S, Griffith O, Coleman C. Therapeutic implications of prolonged treatment with L,S,-Buthione sulfoximine International Journal of Radiation Oncology*Biology*Physics. 24: 204. DOI: 10.1016/0360-3016(92)90269-N |
0.318 |
|
| 1991 |
Campbell EB, Hayward ML, Griffith OW. Analytical and preparative separation of the diastereomers of L-buthionine (SR)-sulfoximine, a potent inhibitor of glutathione biosynthesis. Analytical Biochemistry. 194: 268-77. PMID 1677799 DOI: 10.1016/0003-2697(91)90229-M |
0.316 |
|
| 1991 |
Welch WJ, Wilcox CS, Aisaka K, Gross SS, Griffith OW, Fontoura BMA, Maack T, Levi R. Nitric oxide synthesis from L-arginine modulates renal vascular resistance in isolated perfused and intact rat kidneys Journal of Cardiovascular Pharmacology. 17: S165-S168. DOI: 10.1097/00005344-199100001-00030 |
0.346 |
|
| 1990 |
Kilbourn RG, Gross SS, Jubran A, Adams J, Griffith OW, Levi R, Lodato RF. NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 87: 3629-32. PMID 2333306 DOI: 10.1073/Pnas.87.9.3629 |
0.408 |
|
| 1990 |
Fasehun OA, Gross SS, Rubin LE, Jaffe EA, Griffith OW, Levi R. L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor. The Journal of Pharmacology and Experimental Therapeutics. 255: 1348-53. PMID 2175803 |
0.3 |
|
| 1990 |
Aisaki K, Gross SS, Griffith OW, Levi R. Bradykinin-induced hypotension in the anesthetized guinea pig: Resolution into nitric oxide- and prostaglandin-mediated phases European Journal of Pharmacology. 183: 1786. DOI: 10.1016/0014-2999(90)92102-O |
0.333 |
|
| 1980 |
Beamer RL, Griffith OW, Gass JD, Anderson ME, Meister A. Interaction of L- and D-3-amino-1-chloro-2-pentanone with gamma-glutamylcysteine synthetase Journal of Biological Chemistry. 255: 11732-11736. PMID 6108326 |
0.338 |
|
| 1980 |
Griffith OW, Tate SS. The apparent glutathione oxidase activity of gamma-glutamyl transpeptidase. Chemical mechanism. The Journal of Biological Chemistry. 255: 5011-4. PMID 6102993 |
0.313 |
|
| 1979 |
Meister A, Griffith OW, Novogrodsky A, Tate SS. New aspects of glutathione metabolism and translocation in mammals. Ciba Foundation Symposium. 135-61. PMID 45011 DOI: 10.1002/9780470720554.ch9 |
0.303 |
|
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