| Year |
Citation |
Score |
| 2022 |
Prieto MD, Jang J, Franciosi AN, Av-Gay Y, Bach H, Tebbutt SJ, Quon BS. Whole blood RNA-seq demonstrates an increased host immune response in individuals with cystic fibrosis who develop nontuberculous mycobacterial pulmonary disease. Plos One. 17: e0278296. PMID 36480571 DOI: 10.1371/journal.pone.0278296 |
0.529 |
|
| 2022 |
Tsui CKM, Sorrentino F, Narula G, Mendoza-Losana A, Del Rio RG, Herrán EP, Lopez A, Bojang A, Zheng X, Remuiñán-Blanco MJ, Av-Gay Y. Hit Compounds and Associated Targets in Intracellular . Molecules (Basel, Switzerland). 27. PMID 35889319 DOI: 10.3390/molecules27144446 |
0.7 |
|
| 2021 |
Persaud R, Li SC, Chao JD, Forestieri R, Donohue E, Balgi AD, Zheng X, Chao JT, Yashiroda Y, Yoshimura M, Loewen CJR, Gingras AC, Boone C, Av-Gay Y, Roberge M, et al. Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1. Cell Chemical Biology. PMID 34520745 DOI: 10.1016/j.chembiol.2021.07.017 |
0.308 |
|
| 2020 |
Shapira T, Rankine-Wilson L, Chao JD, Pichler V, Rens C, Pfeifer T, Av-Gay Y. High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against . Frontiers in Microbiology. 11: 553962. PMID 33042061 DOI: 10.3389/Fmicb.2020.553962 |
0.372 |
|
| 2020 |
L Moure A, Narula G, Sorrentino F, Bojang A, K M Tsui C, Sao Emani C, Porras-De Francisco E, Diaz B, Rebollo-Lopez MJ, Torres Gómez PA, Lopez-Roman EM, Camino I, Casado Castro P, Guijarro López L, Ortega F, ... ... Av-Gay Y, et al. A MymA bioactivated thioalkyl-benzoxazole prodrug family active against Mycobacterium tuberculosis. Journal of Medicinal Chemistry. PMID 32275415 DOI: 10.1021/Acs.Jmedchem.0C00003 |
0.73 |
|
| 2019 |
Richter A, Shapira T, Av-Gay Y. THP-1 and infection models for screening and characterization of anti- hit compounds. Antimicrobial Agents and Chemotherapy. PMID 31636068 DOI: 10.1128/Aac.01601-19 |
0.382 |
|
| 2019 |
Heinkel F, Abraham L, Ko M, Chao J, Bach H, Hui LT, Li H, Zhu M, Ling YM, Rogalski JC, Scurll J, Bui JM, Mayor T, Gold MR, Chou KC, ... Av-Gay Y, et al. Phase separation and clustering of an ABC transporter in . Proceedings of the National Academy of Sciences of the United States of America. PMID 31366629 DOI: 10.1073/Pnas.1820683116 |
0.603 |
|
| 2019 |
Kaner Z, Engelman R, Schuster R, Rider P, Greenberg D, Av-Gay Y, Benhar M, Lewis EC. S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination. Frontiers in Immunology. 10: 590. PMID 31001247 DOI: 10.3389/Fimmu.2019.00590 |
0.349 |
|
| 2018 |
Richter A, Strauch A, Chao J, Ko M, Av-Gay Y. Screening of preselected libraries targeting for drug discovery. Antimicrobial Agents and Chemotherapy. PMID 30012760 DOI: 10.1128/Aac.00828-18 |
0.318 |
|
| 2018 |
Laqua K, Klemm M, Richard-Greenblatt M, Richter A, Liebe L, Huang T, Lin S, Guardia A, Pérez-Herran E, Ballell L, Av-Gay Y, Imming P. Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides. Bioorganic & Medicinal Chemistry. PMID 29706526 DOI: 10.1016/J.Bmc.2018.04.045 |
0.402 |
|
| 2018 |
Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y. Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages. Scientific Reports. 8: 155. PMID 29317718 DOI: 10.1038/S41598-017-18547-9 |
0.473 |
|
| 2017 |
Tsui CKM, Wong D, Narula G, Gardy JL, Hsiao WWH, Av-Gay Y. Genome Sequences of the Mycobacterium tuberculosis H37Rv-ptkA Deletion Mutant and Its Parental Strain. Genome Announcements. 5. PMID 29097456 DOI: 10.1128/Genomea.01156-17 |
0.38 |
|
| 2017 |
Zheng X, Av-Gay Y. System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis. Journal of Visualized Experiments : Jove. PMID 28448028 DOI: 10.3791/55273 |
0.432 |
|
| 2017 |
Margel D, Mizrahi M, Regev-Shoshani G, Ko M, Moshe M, Ozalvo R, Shavit-Grievink L, Baniel J, Kedar D, Yossepowitch O, Lifshitz D, Nadu A, Greenberg D, Av-Gay Y. Nitric oxide charged catheters as a potential strategy for prevention of hospital acquired infections. Plos One. 12: e0174443. PMID 28410367 DOI: 10.1371/Journal.Pone.0174443 |
0.301 |
|
| 2017 |
Richard-Greenblatt M, Av-Gay Y. Epigenetic Phosphorylation Control of Mycobacterium tuberculosis Infection and Persistence. Microbiology Spectrum. 5. PMID 28281439 DOI: 10.1128/Microbiolspec.Tbtb2-0005-2015 |
0.471 |
|
| 2016 |
Saini V, Cumming BM, Guidry L, Lamprecht DA, Adamson JH, Reddy VP, Chinta KC, Mazorodze JH, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, et al. Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell Reports. 14: 572-85. PMID 26774486 DOI: 10.1016/J.Celrep.2015.12.056 |
0.636 |
|
| 2016 |
Zheng X, Av-Gay Y. New Era of TB Drug Discovery and Its Impact on Disease Management Current Treatment Options in Infectious Diseases. 8: 299-310. DOI: 10.1007/S40506-016-0098-0 |
0.352 |
|
| 2015 |
Poirier V, Av-Gay Y. Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms. Microbiology Spectrum. 3. PMID 27337278 DOI: 10.1128/Microbiolspec.Vmbf-0003-2014 |
0.705 |
|
| 2015 |
Sorrentino F, Gonzalez Del Rio R, Zheng X, Presa JM, Torres Gomez P, Martinez Hoyos M, Perez Herran ME, Mendoza Losana A, Av-Gay Y. Development of an intracellular screen for new compounds able to inhibit Mycobacterium tuberculosis growth in human macrophages. Antimicrobial Agents and Chemotherapy. PMID 26503663 DOI: 10.1128/Aac.01920-15 |
0.724 |
|
| 2015 |
Zhou P, Wong D, Li W, Xie J, Av-Gay Y. Phosphorylation of Mycobacterium tuberculosis protein tyrosine kinase A PtkA by Ser/Thr protein kinases. Biochemical and Biophysical Research Communications. PMID 26417687 DOI: 10.1016/J.Bbrc.2015.09.124 |
0.436 |
|
| 2015 |
Richard-Greenblatt M, Bach H, Adamson J, Peña-Diaz S, Li W, Steyn AJ, Av-Gay Y. Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity. The Journal of Biological Chemistry. 290: 23064-76. PMID 26229105 DOI: 10.1074/Jbc.M115.648642 |
0.665 |
|
| 2015 |
Hmama Z, Peña-Díaz S, Joseph S, Av-Gay Y. Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis. Immunological Reviews. 264: 220-32. PMID 25703562 DOI: 10.1111/Imr.12268 |
0.41 |
|
| 2015 |
Zhou P, Li W, Wong D, Xie J, Av-Gay Y. Phosphorylation control of protein tyrosine phosphatase A activity in Mycobacterium tuberculosis. Febs Letters. 589: 326-31. PMID 25535696 DOI: 10.1016/J.Febslet.2014.12.015 |
0.411 |
|
| 2015 |
Saini V, Cumming BM, Guidry L, Lamprecht DA, Adamson JH, Reddy VP, Chinta KC, Mazorodze JH, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, et al. Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis Cell Reports. DOI: 10.1016/j.celrep.2015.12.056 |
0.595 |
|
| 2014 |
Poirier V, Bach H, Av-Gay Y. Mycobacterium tuberculosis promotes anti-apoptotic activity of the macrophage by PtpA protein-dependent dephosphorylation of host GSK3α. The Journal of Biological Chemistry. 289: 29376-85. PMID 25187516 DOI: 10.1074/Jbc.M114.582502 |
0.796 |
|
| 2014 |
Chao JD, Wong D, Av-Gay Y. Microbial protein-tyrosine kinases. The Journal of Biological Chemistry. 289: 9463-72. PMID 24554699 DOI: 10.1074/Jbc.R113.520015 |
0.352 |
|
| 2013 |
Sun J, Singh V, Lau A, Stokes RW, Obregón-Henao A, Orme IM, Wong D, Av-Gay Y, Hmama Z. Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity. Plos Pathogens. 9: e1003499. PMID 23874203 DOI: 10.1371/Journal.Ppat.1003499 |
0.441 |
|
| 2013 |
Regev-Shoshani G, Vimalanathan S, McMullin B, Road J, Av-Gay Y, Miller C. Gaseous nitric oxide reduces influenza infectivity in vitro. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 31: 48-53. PMID 23562771 DOI: 10.1016/J.Niox.2013.03.007 |
0.559 |
|
| 2013 |
Martínez-Gutiérrez F, Guajardo-Pacheco JM, Noriega-Trevino ME, Thi EP, Reiner N, Orrantia E, Av-Gay Y, Ruiz F, Bach H. Antimicrobial activity, cytotoxicity and inflammatory response of novel plastics embedded with silver nanoparticles. Future Microbiology. 8: 403-11. PMID 23464375 DOI: 10.2217/Fmb.13.5 |
0.586 |
|
| 2013 |
Gómez-Velasco A, Bach H, Rana AK, Cox LR, Bhatt A, Besra GS, Av-Gay Y. Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis. Microbiology (Reading, England). 159: 726-36. PMID 23412844 DOI: 10.1099/Mic.0.062067-0 |
0.675 |
|
| 2013 |
Wong D, Chao JD, Av-Gay Y. Mycobacterium tuberculosis-secreted phosphatases: from pathogenesis to targets for TB drug development. Trends in Microbiology. 21: 100-9. PMID 23084287 DOI: 10.1016/J.Tim.2012.09.002 |
0.466 |
|
| 2013 |
Bach SM, Perotti ME, Merep AP, Marcial GE, Grau A, Attarian R, Av-Gay Y, Bach H, Catalán CA. Chemical constituents, anti-inflammatory and antioxidant activities of bark extracts from Prunus tucumanensis Lillo. Natural Product Research. 27: 916-9. PMID 22889184 DOI: 10.1080/14786419.2012.668693 |
0.59 |
|
| 2013 |
Liu X, Song F, Ma L, Chen C, Xiao X, Ren B, Dai H, Piggott AM, Av-Gay Y, Zhang L, Capon RJ. Sydowiols A-C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii Tetrahedron Letters. 54: 6081-6083. DOI: 10.1016/J.Tetlet.2013.08.137 |
0.38 |
|
| 2012 |
Poirier V, Av-Gay Y. Mycobacterium tuberculosis modulators of the macrophage's cellular events. Microbes and Infection / Institut Pasteur. 14: 1211-9. PMID 22841679 DOI: 10.1016/J.Micinf.2012.07.001 |
0.708 |
|
| 2012 |
Martínez Ruiz MG, Richard-Greenblatt M, Juárez ZN, Av-Gay Y, Bach H, Hernández LR. Antimicrobial, anti-inflammatory, antiparasitic, and cytotoxic activities of Laennecia confusa. Thescientificworldjournal. 2012: 263572. PMID 22623891 DOI: 10.1100/2012/263572 |
0.602 |
|
| 2012 |
Lam KK, Zheng X, Forestieri R, Balgi AD, Nodwell M, Vollett S, Anderson HJ, Andersen RJ, Av-Gay Y, Roberge M. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. Plos Pathogens. 8: e1002691. PMID 22589723 DOI: 10.1371/Journal.Ppat.1002691 |
0.437 |
|
| 2012 |
Miller C, Miller M, McMullin B, Regev G, Serghides L, Kain K, Road J, Av-Gay Y. A phase I clinical study of inhaled nitric oxide in healthy adults. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 11: 324-31. PMID 22520076 DOI: 10.1016/J.Jcf.2012.01.003 |
0.543 |
|
| 2012 |
Burian J, Ramón-García S, Sweet G, Gómez-Velasco A, Av-Gay Y, Thompson CJ. The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance. The Journal of Biological Chemistry. 287: 299-310. PMID 22069311 DOI: 10.1074/Jbc.M111.302588 |
0.367 |
|
| 2012 |
Martínez-Gutierrez F, Thi EP, Silverman JM, de Oliveira CC, Svensson SL, Vanden Hoek A, Sánchez EM, Reiner NE, Gaynor EC, Pryzdial EL, Conway EM, Orrantia E, Ruiz F, Av-Gay Y, Bach H. Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 328-36. PMID 21718674 DOI: 10.1016/J.Nano.2011.06.014 |
0.584 |
|
| 2011 |
Wong D, Bach H, Sun J, Hmama Z, Av-Gay Y. Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification. Proceedings of the National Academy of Sciences of the United States of America. 108: 19371-6. PMID 22087003 DOI: 10.1073/Pnas.1109201108 |
0.658 |
|
| 2011 |
Fortuna AM, Juárez ZN, Bach H, Nematallah A, Av-Gay Y, Sánchez-Arreola E, Catalán CA, Turbay S, Hernández LR. Antimicrobial activities of sesquiterpene lactones and inositol derivatives from Hymenoxys robusta. Phytochemistry. 72: 2413-8. PMID 21963130 DOI: 10.1016/J.Phytochem.2011.09.001 |
0.612 |
|
| 2011 |
Vilchèze C, Av-Gay Y, Barnes SW, Larsen MH, Walker JR, Glynne RJ, Jacobs WR. Coresistance to isoniazid and ethionamide maps to mycothiol biosynthetic genes in Mycobacterium bovis. Antimicrobial Agents and Chemotherapy. 55: 4422-3. PMID 21709101 DOI: 10.1128/Aac.00564-11 |
0.302 |
|
| 2011 |
Bolivar P, Cruz-Paredes C, Hernández LR, Juárez ZN, Sánchez-Arreola E, Av-Gay Y, Bach H. Antimicrobial, anti-inflammatory, antiparasitic, and cytotoxic activities of Galium mexicanum. Journal of Ethnopharmacology. 137: 141-7. PMID 21586319 DOI: 10.1016/J.Jep.2011.04.069 |
0.578 |
|
| 2011 |
Ramón-García S, Ng C, Anderson H, Chao JD, Zheng X, Pfeifer T, Av-Gay Y, Roberge M, Thompson CJ. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrobial Agents and Chemotherapy. 55: 3861-9. PMID 21576426 DOI: 10.1128/Aac.00474-11 |
0.417 |
|
| 2011 |
Xu X, Vilchèze C, Av-Gay Y, Gómez-Velasco A, Jacobs WR. Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis. Antimicrobial Agents and Chemotherapy. 55: 3133-9. PMID 21502624 DOI: 10.1128/Aac.00020-11 |
0.319 |
|
| 2011 |
Bach SM, Fortuna MA, Attarian R, de Trimarco JT, Catalán CA, Av-Gay Y, Bach H. Antibacterial and cytotoxic activities of the sesquiterpene lactones cnicin and onopordopicrin. Natural Product Communications. 6: 163-6. PMID 21425665 DOI: 10.1177/1934578X1100600202 |
0.605 |
|
| 2010 |
Deshayes C, Bach H, Euphrasie D, Attarian R, Coureuil M, Sougakoff W, Laval F, Av-Gay Y, Daffé M, Etienne G, Reyrat JM. MmpS4 promotes glycopeptidolipids biosynthesis and export in Mycobacterium smegmatis. Molecular Microbiology. 78: 989-1003. PMID 21062372 DOI: 10.1111/J.1365-2958.2010.07385.X |
0.627 |
|
| 2010 |
Borrelli S, Zandberg WF, Mohan S, Ko M, Martinez-Gutierrez F, Partha SK, Sanders DA, Av-Gay Y, Pinto BM. Antimycobacterial activity of UDP-galactopyranose mutase inhibitors. International Journal of Antimicrobial Agents. 36: 364-8. PMID 20678902 DOI: 10.1016/J.Ijantimicag.2010.06.030 |
0.432 |
|
| 2010 |
Chao JD, Papavinasasundaram KG, Zheng X, Chávez-Steenbock A, Wang X, Lee GQ, Av-Gay Y. Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 285: 29239-46. PMID 20630871 DOI: 10.1074/Jbc.M110.132894 |
0.429 |
|
| 2010 |
Mascarello A, Chiaradia LD, Vernal J, Villarino A, Guido RV, Perizzolo P, Poirier V, Wong D, Martins PG, Nunes RJ, Yunes RA, Andricopulo AD, Av-Gay Y, Terenzi H. Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth. Bioorganic & Medicinal Chemistry. 18: 3783-9. PMID 20462762 DOI: 10.1016/J.Bmc.2010.04.051 |
0.736 |
|
| 2010 |
Martinez-Gutierrez F, Olive PL, Banuelos A, Orrantia E, Nino N, Sanchez EM, Ruiz F, Bach H, Av-Gay Y. Synthesis, characterization, and evaluation of antimicrobial and cytotoxic effect of silver and titanium nanoparticles. Nanomedicine : Nanotechnology, Biology, and Medicine. 6: 681-8. PMID 20215045 DOI: 10.1016/J.Nano.2010.02.001 |
0.582 |
|
| 2010 |
Movahedzadeh F, Wheeler PR, Dinadayala P, Av-Gay Y, Parish T, Daffé M, Stoker NG. Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis. Bmc Microbiology. 10: 50. PMID 20167072 DOI: 10.1186/1471-2180-10-50 |
0.383 |
|
| 2010 |
Regev-Shoshani G, Ko M, Miller C, Av-Gay Y. Slow release of nitric oxide from charged catheters and its effect on biofilm formation by Escherichia coli. Antimicrobial Agents and Chemotherapy. 54: 273-9. PMID 19884372 DOI: 10.1128/Aac.00511-09 |
0.58 |
|
| 2010 |
Chao J, Wong D, Zheng X, Poirier V, Bach H, Hmama Z, Av-Gay Y. Protein kinase and phosphatase signaling in Mycobacterium tuberculosis physiology and pathogenesis. Biochimica Et Biophysica Acta. 1804: 620-7. PMID 19766738 DOI: 10.1016/J.Bbapap.2009.09.008 |
0.789 |
|
| 2009 |
Attarian R, Bennie C, Bach H, Av-Gay Y. Glutathione disulfide and S-nitrosoglutathione detoxification by Mycobacterium tuberculosis thioredoxin system. Febs Letters. 583: 3215-20. PMID 19737561 DOI: 10.1016/J.Febslet.2009.09.007 |
0.641 |
|
| 2009 |
Bach H, Wong D, Av-Gay Y. Mycobacterium tuberculosis PtkA is a novel protein tyrosine kinase whose substrate is PtpA. The Biochemical Journal. 420: 155-60. PMID 19366344 DOI: 10.1042/Bj20090478 |
0.647 |
|
| 2009 |
Gopalaswamy R, Narayanan S, Chen B, Jacobs WR, Av-Gay Y. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. Fems Microbiology Letters. 295: 23-9. PMID 19341393 DOI: 10.1111/J.1574-6968.2009.01570.X |
0.458 |
|
| 2009 |
Miller C, McMullin B, Ghaffari A, Stenzler A, Pick N, Roscoe D, Ghahary A, Road J, Av-Gay Y. Gaseous nitric oxide bactericidal activity retained during intermittent high-dose short duration exposure. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 20: 16-23. PMID 18789393 DOI: 10.1016/J.Niox.2008.08.002 |
0.593 |
|
| 2008 |
Hegymegi-Barakonyi B, Székely R, Varga Z, Kiss R, Borbély G, Németh G, Bánhegyi P, Pató J, Greff Z, Horváth Z, Mészáros G, Marosfalvi J, ErÅs D, Szántai-Kis C, Breza N, ... ... Av-Gay Y, et al. Signalling inhibitors against Mycobacterium tuberculosis--early days of a new therapeutic concept in tuberculosis. Current Medicinal Chemistry. 15: 2760-70. PMID 18991635 DOI: 10.2174/092986708786242886 |
0.43 |
|
| 2008 |
Vilchèze C, Av-Gay Y, Attarian R, Liu Z, Hazbón MH, Colangeli R, Chen B, Liu W, Alland D, Sacchettini JC, Jacobs WR. Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis. Molecular Microbiology. 69: 1316-29. PMID 18651841 DOI: 10.1111/J.1365-2958.2008.06365.X |
0.385 |
|
| 2008 |
Bach H, Papavinasasundaram KG, Wong D, Hmama Z, Av-Gay Y. Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B. Cell Host & Microbe. 3: 316-22. PMID 18474358 DOI: 10.1016/J.Chom.2008.03.008 |
0.692 |
|
| 2008 |
Lakshminarayan H, Narayanan S, Bach H, Sundaram KG, Av-Gay Y. Molecular cloning and biochemical characterization of a serine threonine protein kinase, PknL, from Mycobacterium tuberculosis. Protein Expression and Purification. 58: 309-17. PMID 18276158 DOI: 10.1016/J.Pep.2007.12.012 |
0.647 |
|
| 2008 |
Gopalaswamy R, Narayanan S, Jacobs WR, Av-Gay Y. Mycobacterium smegmatis biofilm formation and sliding motility are affected by the serine/threonine protein kinase PknF. Fems Microbiology Letters. 278: 121-7. PMID 18031532 DOI: 10.1111/J.1574-6968.2007.00989.X |
0.393 |
|
| 2007 |
Soualhine H, Deghmane AE, Sun J, Mak K, Talal A, Av-Gay Y, Hmama Z. Mycobacterium bovis bacillus Calmette-Guérin secreting active cathepsin S stimulates expression of mature MHC class II molecules and antigen presentation in human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 179: 5137-45. PMID 17911599 DOI: 10.4049/Jimmunol.179.8.5137 |
0.34 |
|
| 2007 |
Deghmane AE, Soualhine H, Soulhine H, Bach H, Sendide K, Itoh S, Tam A, Noubir S, Talal A, Lo R, Toyoshima S, Av-Gay Y, Hmama Z. Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation. Journal of Cell Science. 120: 2796-806. PMID 17652161 DOI: 10.1242/Jcs.006221 |
0.665 |
|
| 2007 |
Miller CC, Rawat M, Johnson T, Av-Gay Y. Innate protection of Mycobacterium smegmatis against the antimicrobial activity of nitric oxide is provided by mycothiol. Antimicrobial Agents and Chemotherapy. 51: 3364-6. PMID 17638697 DOI: 10.1128/Aac.00347-07 |
0.583 |
|
| 2007 |
Zheng X, Papavinasasundaram KG, Av-Gay Y. Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase. Biochemical and Biophysical Research Communications. 355: 162-8. PMID 17286964 DOI: 10.1016/J.Bbrc.2007.01.122 |
0.39 |
|
| 2007 |
Rawat M, Av-Gay Y. Mycothiol-dependent proteins in actinomycetes. Fems Microbiology Reviews. 31: 278-92. PMID 17286835 DOI: 10.1111/J.1574-6976.2006.00062.X |
0.315 |
|
| 2006 |
Bach H, Sun J, Hmama Z, Av-Gay Y. Mycobacterium avium subsp. paratuberculosis PtpA is an endogenous tyrosine phosphatase secreted during infection. Infection and Immunity. 74: 6540-6. PMID 16982836 DOI: 10.1128/Iai.01106-06 |
0.656 |
|
| 2006 |
Pérez J, Garcia R, Bach H, de Waard JH, Jacobs WR, Av-Gay Y, Bubis J, Takiff HE. Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD. Biochemical and Biophysical Research Communications. 348: 6-12. PMID 16879801 DOI: 10.1016/J.Bbrc.2006.06.164 |
0.651 |
|
| 2006 |
Newton GL, Ko M, Ta P, Av-Gay Y, Fahey RC. Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme. Protein Expression and Purification. 47: 542-50. PMID 16630724 DOI: 10.1016/J.Pep.2006.03.003 |
0.345 |
|
| 2006 |
Pick N, Rawat M, Arad D, Lan J, Fan J, Kende AS, Av-Gay Y. In vitro properties of antimicrobial bromotyrosine alkaloids. Journal of Medical Microbiology. 55: 407-15. PMID 16533988 DOI: 10.1099/Jmm.0.46319-0 |
0.368 |
|
| 2005 |
Papavinasasundaram KG, Chan B, Chung JH, Colston MJ, Davis EO, Av-Gay Y. Deletion of the Mycobacterium tuberculosis pknH gene confers a higher bacillary load during the chronic phase of infection in BALB/c mice. Journal of Bacteriology. 187: 5751-60. PMID 16077122 DOI: 10.1128/Jb.187.16.5751-5760.2005 |
0.407 |
|
| 2005 |
Hestvik AL, Hmama Z, Av-Gay Y. Mycobacterial manipulation of the host cell. Fems Microbiology Reviews. 29: 1041-50. PMID 16040149 DOI: 10.1016/J.Femsre.2005.04.013 |
0.349 |
|
| 2005 |
Dosanjh NS, Rawat M, Chung JH, Av-Gay Y. Thiol specific oxidative stress response in Mycobacteria. Fems Microbiology Letters. 249: 87-94. PMID 16006064 DOI: 10.1016/J.Femsle.2005.06.004 |
0.333 |
|
| 2004 |
Pick N, Cameron S, Arad D, Av-Gay Y. Screening of Compounds Toxicity against Human Monocytic cell line-THP-1 by Flow Cytometry. Biological Procedures Online. 6: 220-225. PMID 15472722 DOI: 10.1251/Bpo92 |
0.375 |
|
| 2004 |
Rawat M, Uppal M, Newton G, Steffek M, Fahey RC, Av-Gay Y. Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein. Journal of Bacteriology. 186: 6050-8. PMID 15342574 DOI: 10.1128/Jb.186.18.6050-6058.2004 |
0.378 |
|
| 2004 |
Cowley S, Ko M, Pick N, Chow R, Downing KJ, Gordhan BG, Betts JC, Mizrahi V, Smith DA, Stokes RW, Av-Gay Y. The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo. Molecular Microbiology. 52: 1691-702. PMID 15186418 DOI: 10.1111/J.1365-2958.2004.04085.X |
0.427 |
|
| 2004 |
Movahedzadeh F, Smith DA, Norman RA, Dinadayala P, Murray-Rust J, Russell DG, Kendall SL, Rison SC, McAlister MS, Bancroft GJ, McDonald NQ, Daffe M, Av-Gay Y, Stoker NG. The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence. Molecular Microbiology. 51: 1003-14. PMID 14763976 DOI: 10.1046/J.1365-2958.2003.03900.X |
0.366 |
|
| 2003 |
Steffek M, Newton GL, Av-Gay Y, Fahey RC. Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase. Biochemistry. 42: 12067-76. PMID 14556638 DOI: 10.1021/Bi030080U |
0.366 |
|
| 2003 |
Hestvik AL, Hmama Z, Av-Gay Y. Kinome analysis of host response to mycobacterial infection: a novel technique in proteomics. Infection and Immunity. 71: 5514-22. PMID 14500469 DOI: 10.1128/Iai.71.10.5514-5522.2003 |
0.427 |
|
| 2003 |
Maynes JT, Garen C, Cherney MM, Newton G, Arad D, Av-Gay Y, Fahey RC, James MN. The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold. The Journal of Biological Chemistry. 278: 47166-70. PMID 12958317 DOI: 10.1074/Jbc.M308914200 |
0.309 |
|
| 2003 |
Newton GL, Koledin T, Gorovitz B, Rawat M, Fahey RC, Av-Gay Y. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). Journal of Bacteriology. 185: 3476-9. PMID 12754249 DOI: 10.1128/Jb.185.11.3476-3479.2003 |
0.326 |
|
| 2003 |
Rawat M, Kovacevic S, Billman-Jacobe H, Av-Gay Y. Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis. Microbiology (Reading, England). 149: 1341-9. PMID 12724395 DOI: 10.1099/Mic.0.26084-0 |
0.316 |
|
| 2003 |
Rawat M, Heys J, Av-Gay Y. Identification and characterization of a diamide sensitive mutant of Mycobacterium smegmatis. Fems Microbiology Letters. 220: 161-9. PMID 12670676 DOI: 10.1016/S0378-1097(03)00127-7 |
0.34 |
|
| 2002 |
Brinkman FS, Blanchard JL, Cherkasov A, Av-Gay Y, Brunham RC, Fernandez RC, Finlay BB, Otto SP, Ouellette BF, Keeling PJ, Rose AM, Hancock RE, Jones SJ, Greberg H. Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. Genome Research. 12: 1159-67. PMID 12176923 DOI: 10.1101/Gr.341802 |
0.322 |
|
| 2002 |
Cowley SC, Babakaiff R, Av-Gay Y. Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA. Research in Microbiology. 153: 233-41. PMID 12066895 DOI: 10.1016/S0923-2508(02)01309-8 |
0.416 |
|
| 2001 |
Drews SJ, Hung F, Av-Gay Y. A protein kinase inhibitor as an antimycobacterial agent. Fems Microbiology Letters. 205: 369-74. PMID 11750829 DOI: 10.1111/J.1574-6968.2001.Tb10974.X |
0.608 |
|
| 2001 |
Cowley SC, Av-Gay Y. Monitoring promoter activity and protein localization in Mycobacterium spp. using green fluorescent protein Gene. 264: 225-231. PMID 11250077 DOI: 10.1016/S0378-1119(01)00336-5 |
0.363 |
|
| 2000 |
Newton GL, Av-Gay Y, Fahey RC. N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis. Journal of Bacteriology. 182: 6958-63. PMID 11092856 DOI: 10.1128/Jb.182.24.6958-6963.2000 |
0.374 |
|
| 2000 |
Newton GL, Av-Gay Y, Fahey RC. A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase. Biochemistry. 39: 10739-46. PMID 10978158 DOI: 10.1021/Bi000356N |
0.328 |
|
| 2000 |
Mahenthiralingam E, Bischof J, Byrne SK, Radomski C, Davies JE, Av-Gay Y, Vandamme P. DNA-based diagnostic approaches for identification of Burkholderia cepacia complex, Burkholderia vietnamiensis, Burkholderia multivorans, Burkholderia stabilis, and Burkholderia cepacia genomovars I and III Journal of Clinical Microbiology. 38: 3165-3173. PMID 10970351 DOI: 10.1128/Jcm.38.9.3165-3173.2000 |
0.461 |
|
| 2000 |
Av-Gay Y, Everett M. The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis Trends in Microbiology. 8: 238-244. PMID 10785641 DOI: 10.1016/S0966-842X(00)01734-0 |
0.449 |
|
| 1999 |
Av-Gay Y, Jamil S, Drews SJ. Expression and characterization of the Mycobacterium tuberculosis serine/threonine protein kinase PknB. Infection and Immunity. 67: 5676-82. PMID 10531215 DOI: 10.1128/Iai.67.11.5676-5682.1999 |
0.624 |
|
| 1999 |
Newton GL, Unson MD, Anderberg SJ, Aguilera JA, Oh NN, delCardayre SB, Av-Gay Y, Fahey RC. Characterization of Mycobacterium smegmatis mutants defective in 1-d-myo-inosityl-2-amino-2-deoxy-alpha-d-glucopyranoside and mycothiol biosynthesis. Biochemical and Biophysical Research Communications. 255: 239-44. PMID 10049692 DOI: 10.1006/Bbrc.1999.0156 |
0.308 |
|
| 1998 |
Gal-Mor O, Borovok I, Av-Gay Y, Cohen G, Aharonowitz Y. Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria Gene. 217: 83-90. PMID 9795152 DOI: 10.1016/S0378-1119(98)00357-6 |
0.585 |
|
| 1997 |
AV-GAY Y, DAVIES J. Components of Eukaryotic-like Protein Signaling Pathways inMycobacterium tuberculosis Microbial & Comparative Genomics. 2: 63-73. DOI: 10.1089/Omi.1.1997.2.63 |
0.535 |
|
| 1993 |
Aharonowitz Y, Av-Gay Y, Schreiber R, Cohen G. Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in β-lactam antibiotic biosynthesis Journal of Bacteriology. 175: 623-629. PMID 8423136 DOI: 10.1128/Jb.175.3.623-629.1993 |
0.648 |
|
| 1993 |
Cohen G, Yanko M, Mislovati M, Argaman A, Schreiber R, Av-Gay Y, Aharonowitz Y. Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: Sequences, expression, and organization of the genes Journal of Bacteriology. 175: 5159-5167. PMID 8349555 DOI: 10.1128/Jb.175.16.5159-5167.1993 |
0.641 |
|
| 1992 |
Av-gay Y, Aharonowitz Y, Cohen G. Streptomyces contain a 7.0 KDa cold shock like protein Nucleic Acids Research. 20: 5478. PMID 1437568 DOI: 10.1093/Nar/20.20.5478 |
0.598 |
|
| 1991 |
Landman O, Shiffman D, Av-Gay Y, Aharonowitz Y, Cohen G. High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies Fems Microbiology Letters. 84: 239-244. PMID 1666621 |
0.609 |
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