| Year |
Citation |
Score |
| 2016 |
Silva IN, Santos PM, Santos MR, Zlosnik JE, Speert DP, Buskirk SW, Bruger EL, Waters CM, Cooper VS, Moreira LM. Long-Term Evolution of Burkholderia multivorans during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection. Msystems. 1. PMID 27822534 DOI: 10.1128/mSystems.00029-16 |
0.309 |
|
| 2015 |
Kennedy S, Beaudoin T, Yau YC, Caraher E, Zlosnik JE, Speert DP, LiPuma JJ, Tullis E, Waters V. Activity of tobramycin against cystic fibrosis isolates of Burkholderia cepacia complex grown as biofilms. Antimicrobial Agents and Chemotherapy. PMID 26503664 DOI: 10.1128/Aac.02068-15 |
0.374 |
|
| 2015 |
LaFayette SL, Houle D, Beaudoin T, Wojewodka G, Radzioch D, Hoffman LR, Burns JL, Dandekar AA, Smalley NE, Chandler JR, Zlosnik JE, Speert DP, Bernier J, Matouk E, Brochiero E, et al. Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses. Science Advances. 1. PMID 26457326 DOI: 10.1126/Sciadv.1500199 |
0.421 |
|
| 2015 |
Loutet SA, El-Halfawy OM, Jassem AN, López JM, Medarde AF, Speert DP, Davies JE, Valvano MA. Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia. International Journal of Antimicrobial Agents. PMID 26187366 DOI: 10.1016/J.Ijantimicag.2015.05.010 |
0.377 |
|
| 2015 |
Zlosnik JE, Zhou G, Brant R, Henry DA, Hird TJ, Mahenthiralingam E, Chilvers MA, Wilcox P, Speert DP. Burkholderia species infections in patients with cystic fibrosis in British Columbia, Canada. 30 years' experience. Annals of the American Thoracic Society. 12: 70-8. PMID 25474359 DOI: 10.1513/Annalsats.201408-395Oc |
0.382 |
|
| 2015 |
Yau YC, Ratjen F, Tullis E, Wilcox P, Freitag A, Chilvers M, Grasemann H, Zlosnik J, Speert D, Corey M, Stanojevic S, Matukas L, Leahy TR, Shih S, Waters V. Randomized controlled trial of biofilm antimicrobial susceptibility testing in cystic fibrosis patients. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 14: 262-6. PMID 25453872 DOI: 10.1016/J.Jcf.2014.09.013 |
0.394 |
|
| 2015 |
Ratjen A, Yau Y, Wettlaufer J, Matukas L, Zlosnik JE, Speert DP, LiPuma JJ, Tullis E, Waters V. In vitro efficacy of high-dose tobramycin against Burkholderia cepacia complex and Stenotrophomonas maltophilia isolates from cystic fibrosis patients. Antimicrobial Agents and Chemotherapy. 59: 711-3. PMID 25348526 DOI: 10.1128/Aac.04123-14 |
0.406 |
|
| 2014 |
de la Fuente-Núñez C, Mansour SC, Wang Z, Jiang L, Breidenstein EB, Elliott M, Reffuveille F, Speert DP, Reckseidler-Zenteno SL, Shen Y, Haapasalo M, Hancock RE. Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients. Antibiotics (Basel, Switzerland). 3: 509-526. PMID 26221537 DOI: 10.3390/Antibiotics3040509 |
0.38 |
|
| 2014 |
Zlosnik JE, Mori PY, To D, Leung J, Hird TJ, Speert DP. Swimming motility in a longitudinal collection of clinical isolates of Burkholderia cepacia complex bacteria from people with cystic fibrosis. Plos One. 9: e106428. PMID 25203161 DOI: 10.1371/Journal.Pone.0106428 |
0.446 |
|
| 2014 |
Malott RJ, Wu CH, Lee TD, Hird TJ, Dalleska NF, Zlosnik JE, Newman DK, Speert DP. Fosmidomycin decreases membrane hopanoids and potentiates the effects of colistin on Burkholderia multivorans clinical isolates. Antimicrobial Agents and Chemotherapy. 58: 5211-9. PMID 24957830 DOI: 10.1128/Aac.02705-14 |
0.388 |
|
| 2014 |
Jassem AN, Forbes CM, Speert DP. Investigation of aminoglycoside resistance inducing conditions and a putative AmrAB-OprM efflux system in Burkholderia vietnamiensis. Annals of Clinical Microbiology and Antimicrobials. 13: 2. PMID 24393536 DOI: 10.1186/1476-0711-13-2 |
0.385 |
|
| 2013 |
Huse HK, Kwon T, Zlosnik JE, Speert DP, Marcotte EM, Whiteley M. Pseudomonas aeruginosa enhances production of a non-alginate exopolysaccharide during long-term colonization of the cystic fibrosis lung. Plos One. 8: e82621. PMID 24324811 DOI: 10.1371/Journal.Pone.0082621 |
0.387 |
|
| 2013 |
Dias C, McDonald A, Sincan M, Rupps R, Markello T, Salvarinova R, Santos RF, Menghrajani K, Ahaghotu C, Sutherland DP, Fortuno ES, Kollmann TR, Demos M, Friedman JM, Speert DP, et al. Recurrent subacute post-viral onset of ataxia associated with a PRF1 mutation. European Journal of Human Genetics : Ejhg. 21: 1232-9. PMID 23443029 DOI: 10.1038/Ejhg.2013.20 |
0.311 |
|
| 2013 |
Behrends V, Ryall B, Zlosnik JE, Speert DP, Bundy JG, Williams HD. Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections. Environmental Microbiology. 15: 398-408. PMID 22882524 DOI: 10.1111/J.1462-2920.2012.02840.X |
0.421 |
|
| 2012 |
Zlosnik JEA, Gunaratnam LC, Speert DP. Serum susceptibility in clinical isolates of Burkholderia cepacia complex bacteria: development of a growth-based assay for high throughput determination. Frontiers in Cellular and Infection Microbiology. 2: 67. PMID 22919658 DOI: 10.3389/Fcimb.2012.00067 |
0.402 |
|
| 2012 |
Waters V, Zlosnik JE, Yau YC, Speert DP, Aaron SD, Guttman DS. Comparison of three typing methods for Pseudomonas aeruginosa isolates from patients with cystic fibrosis. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 31: 3341-50. PMID 22843295 DOI: 10.1007/S10096-012-1701-Z |
0.381 |
|
| 2012 |
Speert DP. Antimicrobial resistance: Implications for therapy of infections with common childhood pathogens. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 7: 169-73. PMID 22514433 DOI: 10.1155/1996/431214 |
0.336 |
|
| 2012 |
Velapatiño B, Limmathurotsakul D, Peacock SJ, Speert DP. Identification of differentially expressed proteins from Burkholderia pseudomallei isolated during primary and relapsing melioidosis. Microbes and Infection / Institut Pasteur. 14: 335-40. PMID 22172334 DOI: 10.1016/J.Micinf.2011.11.011 |
0.321 |
|
| 2012 |
Malott RJ, Steen-Kinnaird BR, Lee TD, Speert DP. Identification of hopanoid biosynthesis genes involved in polymyxin resistance in Burkholderia multivorans. Antimicrobial Agents and Chemotherapy. 56: 464-71. PMID 22006009 DOI: 10.1128/Aac.00602-11 |
0.364 |
|
| 2011 |
Silva IN, Ferreira AS, Becker JD, Zlosnik JE, Speert DP, He J, Mil-Homens D, Moreira LM. Mucoid morphotype variation of Burkholderia multivorans during chronic cystic fibrosis lung infection is correlated with changes in metabolism, motility, biofilm formation and virulence. Microbiology (Reading, England). 157: 3124-37. PMID 21835880 DOI: 10.1099/Mic.0.050989-0 |
0.391 |
|
| 2011 |
Jassem AN, Zlosnik JE, Henry DA, Hancock RE, Ernst RK, Speert DP. In vitro susceptibility of Burkholderia vietnamiensis to aminoglycosides. Antimicrobial Agents and Chemotherapy. 55: 2256-64. PMID 21321142 DOI: 10.1128/Aac.01434-10 |
0.382 |
|
| 2011 |
Zlosnik JE, Costa PS, Brant R, Mori PY, Hird TJ, Fraenkel MC, Wilcox PG, Davidson AG, Speert DP. Mucoid and nonmucoid Burkholderia cepacia complex bacteria in cystic fibrosis infections. American Journal of Respiratory and Critical Care Medicine. 183: 67-72. PMID 20709823 DOI: 10.1164/Rccm.201002-0203Oc |
0.412 |
|
| 2010 |
Picard C, von Bernuth H, Ghandil P, Chrabieh M, Levy O, Arkwright PD, McDonald D, Geha RS, Takada H, Krause JC, Creech CB, Ku CL, Ehl S, Maródi L, Al-Muhsen S, ... ... Speert DP, et al. Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine. 89: 403-25. PMID 21057262 DOI: 10.1097/Md.0B013E3181Fd8Ec3 |
0.379 |
|
| 2010 |
Huse HK, Kwon T, Zlosnik JE, Speert DP, Marcotte EM, Whiteley M. Parallel evolution in Pseudomonas aeruginosa over 39,000 generations in vivo. Mbio. 1. PMID 20856824 DOI: 10.1128/Mbio.00199-10 |
0.427 |
|
| 2010 |
Zlosnik JE, Speert DP. The role of mucoidy in virulence of bacteria from the Burkholderia cepacia complex: a systematic proteomic and transcriptomic analysis. The Journal of Infectious Diseases. 202: 770-81. PMID 20670172 DOI: 10.1086/655663 |
0.444 |
|
| 2009 |
Vanlaere E, Baldwin A, Gevers D, Henry D, De Brandt E, LiPuma JJ, Mahenthiralingam E, Speert DP, Dowson C, Vandamme P. Taxon K, a complex within the Burkholderia cepacia complex, comprises at least two novel species, Burkholderia contaminans sp. nov. and Burkholderia lata sp. nov. International Journal of Systematic and Evolutionary Microbiology. 59: 102-11. PMID 19126732 DOI: 10.1099/Ijs.0.001123-0 |
0.319 |
|
| 2009 |
Eftekhar F, Speert DP. Biofilm formation by persistent and non-persistent isolates of Staphylococcus epidermidis from a neonatal intensive care unit Journal of Hospital Infection. 71: 112-116. PMID 19013672 DOI: 10.1016/J.Jhin.2008.09.008 |
0.352 |
|
| 2008 |
Mena A, Smith EE, Burns JL, Speert DP, Moskowitz SM, Perez JL, Oliver A. Genetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients is catalyzed by hypermutation. Journal of Bacteriology. 190: 7910-7. PMID 18849421 DOI: 10.1128/Jb.01147-08 |
0.332 |
|
| 2008 |
Brown KL, Bylund J, MacDonald KL, Song-Zhao GX, Elliott MR, Falsafi R, Hancock RE, Speert DP. ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease. Clinical Immunology (Orlando, Fla.). 129: 90-102. PMID 18676204 DOI: 10.1016/J.Clim.2008.06.005 |
0.312 |
|
| 2008 |
MacDonald KL, Speert DP. Differential modulation of innate immune cell functions by the Burkholderia cepacia complex: Burkholderia cenocepacia but not Burkholderia multivorans disrupts maturation and induces necrosis in human dendritic cells. Cellular Microbiology. 10: 2138-49. PMID 18624797 DOI: 10.1111/J.1462-5822.2008.01197.X |
0.36 |
|
| 2008 |
Zlosnik JE, Hird TJ, Fraenkel MC, Moreira LM, Henry DA, Speert DP. Differential mucoid exopolysaccharide production by members of the Burkholderia cepacia complex. Journal of Clinical Microbiology. 46: 1470-3. PMID 18256220 DOI: 10.1128/Jcm.02273-07 |
0.403 |
|
| 2008 |
Baldwin A, Mahenthiralingam E, Drevinek P, Pope C, Waine DJ, Henry DA, Speert DP, Carter P, Vandamme P, LiPuma JJ, Dowson CG. Elucidating global epidemiology of Burkholderia multivorans in cases of cystic fibrosis by multilocus sequence typing. Journal of Clinical Microbiology. 46: 290-5. PMID 18032622 DOI: 10.1128/Jcm.01818-07 |
0.436 |
|
| 2007 |
Ku CL, von Bernuth H, Picard C, Zhang SY, Chang HH, Yang K, Chrabieh M, Issekutz AC, Cunningham CK, Gallin J, Holland SM, Roifman C, Ehl S, Smart J, Tang M, ... ... Speert D, et al. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. The Journal of Experimental Medicine. 204: 2407-22. PMID 17893200 DOI: 10.1084/Jem.20070628 |
0.334 |
|
| 2007 |
Ernst RK, Moskowitz SM, Emerson JC, Kraig GM, Adams KN, Harvey MD, Ramsey B, Speert DP, Burns JL, Miller SI. Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis. The Journal of Infectious Diseases. 196: 1088-92. PMID 17763333 DOI: 10.1086/521367 |
0.348 |
|
| 2007 |
Baldwin A, Mahenthiralingam E, Drevinek P, Vandamme P, Govan JR, Waine DJ, LiPuma JJ, Chiarini L, Dalmastri C, Henry DA, Speert DP, Honeybourne D, Maiden MC, Dowson CG. Environmental Burkholderia cepacia complex isolates in human infections. Emerging Infectious Diseases. 13: 458-61. PMID 17552100 DOI: 10.3201/Eid1303.060403 |
0.399 |
|
| 2007 |
Chung JW, Speert DP. Proteomic identification and characterization of bacterial factors associated with Burkholderia cenocepacia survival in a murine host. Microbiology (Reading, England). 153: 206-14. PMID 17185549 DOI: 10.1099/Mic.0.2006/000455-0 |
0.616 |
|
| 2007 |
Waine DJ, Henry DA, Baldwin A, Speert DP, Honeybourne D, Mahenthiralingam E, Dowson CG. Reliability of multilocus sequence typing of the Burkholderia cepacia complex in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 6: 215-9. PMID 17141579 DOI: 10.1016/J.Jcf.2006.10.003 |
0.345 |
|
| 2006 |
Speert DP. Bacterial infections of the lung in normal and immunodeficient patients. Novartis Foundation Symposium. 279: 42-51; disussion 51-. PMID 17278384 DOI: 10.1002/9780470035399.Ch4 |
0.409 |
|
| 2006 |
Smith EE, Buckley DG, Wu Z, Saenphimmachak C, Hoffman LR, D'Argenio DA, Miller SI, Ramsey BW, Speert DP, Moskowitz SM, Burns JL, Kaul R, Olson MV. Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proceedings of the National Academy of Sciences of the United States of America. 103: 8487-92. PMID 16687478 DOI: 10.1073/Pnas.0602138103 |
0.419 |
|
| 2006 |
Jacobson M, Wray R, Kovach D, Henry D, Speert D, Matlow A. Sustained endemicity of Burkholderia cepacia complex in a pediatric institution, associated with contaminated ultrasound gel. Infection Control and Hospital Epidemiology. 27: 362-6. PMID 16622813 DOI: 10.1086/503343 |
0.357 |
|
| 2006 |
Khashu M, Osiovich H, Henry D, Al Khotani A, Solimano A, Speert DP. Persistent bacteremia and severe thrombocytopenia caused by coagulase-negative Staphylococcus in a neonatal intensive care unit. Pediatrics. 117: 340-8. PMID 16452352 DOI: 10.1542/Peds.2005-0333 |
0.303 |
|
| 2006 |
Yoon SS, Coakley R, Lau GW, Lymar SV, Gaston B, Karabulut AC, Hennigan RF, Hwang SH, Buettner G, Schurr MJ, Mortensen JE, Burns JL, Speert D, Boucher RC, Hassett DJ. Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions. The Journal of Clinical Investigation. 116: 436-46. PMID 16440061 DOI: 10.1172/Jci24684 |
0.413 |
|
| 2006 |
Bylund J, Burgess LA, Cescutti P, Ernst RK, Speert DP. Exopolysaccharides from Burkholderia cenocepacia inhibit neutrophil chemotaxis and scavenge reactive oxygen species. The Journal of Biological Chemistry. 281: 2526-32. PMID 16316987 DOI: 10.1074/Jbc.M510692200 |
0.417 |
|
| 2005 |
Baldwin A, Mahenthiralingam E, Thickett KM, Honeybourne D, Maiden MC, Govan JR, Speert DP, Lipuma JJ, Vandamme P, Dowson CG. Multilocus sequence typing scheme that provides both species and strain differentiation for the Burkholderia cepacia complex. Journal of Clinical Microbiology. 43: 4665-73. PMID 16145124 DOI: 10.1128/Jcm.43.9.4665-4673.2005 |
0.328 |
|
| 2005 |
Husain E, Whitehead S, Castell A, Thomas EE, Speert DP. Viridans streptococci bacteremia in children with malignancy: relevance of species identification and penicillin susceptibility. The Pediatric Infectious Disease Journal. 24: 563-6. PMID 15933573 DOI: 10.1097/01.Inf.0000164708.21464.03 |
0.308 |
|
| 2005 |
Lewis DA, Jones A, Parkhill J, Speert DP, Govan JR, Lipuma JJ, Lory S, Webb AK, Mahenthiralingam E. Identification of DNA markers for a transmissible Pseudomonas aeruginosa cystic fibrosis strain. American Journal of Respiratory Cell and Molecular Biology. 33: 56-64. PMID 15834046 DOI: 10.1165/Rcmb.2004-0352Oc |
0.369 |
|
| 2005 |
Bylund J, Campsall PA, Ma RC, Conway BA, Speert DP. Burkholderia cenocepacia induces neutrophil necrosis in chronic granulomatous disease. Journal of Immunology (Baltimore, Md. : 1950). 174: 3562-9. PMID 15749893 DOI: 10.4049/Jimmunol.174.6.3562 |
0.384 |
|
| 2004 |
Coenye T, Henry D, Speert DP, Vandamme P. Burkholderia phenoliruptrix sp. nov., to accommodate the 2,4,5-trichlorophenoxyacetic acid and halophenol-degrading strain AC1100. Systematic and Applied Microbiology. 27: 623-7. PMID 15612618 DOI: 10.1078/0723202042369992 |
0.313 |
|
| 2004 |
Chu KK, MacDonald KL, Davidson DJ, Speert DP. Persistence of Burkholderia multivorans within the pulmonary macrophage in the murine lung. Infection and Immunity. 72: 6142-7. PMID 15385520 DOI: 10.1128/Iai.72.10.6142-6147.2004 |
0.589 |
|
| 2004 |
Conway BA, Chu KK, Bylund J, Altman E, Speert DP. Production of exopolysaccharide by Burkholderia cenocepacia results in altered cell-surface interactions and altered bacterial clearance in mice. The Journal of Infectious Diseases. 190: 957-66. PMID 15295701 DOI: 10.1086/423141 |
0.581 |
|
| 2004 |
Pollard AJ, Currie A, Rosenberger CM, Heale JP, Finlay BB, Speert DP. Differential post-transcriptional activation of human phagocytes by different Pseudomonas aeruginosa isolates. Cellular Microbiology. 6: 639-50. PMID 15186400 DOI: 10.1111/J.1462-5822.2004.00388.X |
0.371 |
|
| 2004 |
Currie AJ, Davidson DJ, Reid GS, Bharya S, MacDonald KL, Devon RS, Speert DP. Primary immunodeficiency to pneumococcal infection due to a defect in Toll-like receptor signaling. The Journal of Pediatrics. 144: 512-8. PMID 15069402 DOI: 10.1016/J.Jpeds.2003.10.034 |
0.31 |
|
| 2003 |
Currie AJ, Speert DP, Davidson DJ. Pseudomonas aeruginosa: role in the pathogenesis of the CF lung lesion. Seminars in Respiratory and Critical Care Medicine. 24: 671-80. PMID 16088583 DOI: 10.1055/S-2004-815663 |
0.417 |
|
| 2003 |
Chung JW, Altman E, Beveridge TJ, Speert DP. Colonial morphology of Burkholderia cepacia complex genomovar III: implications in exopolysaccharide production, pilus expression, and persistence in the mouse. Infection and Immunity. 71: 904-9. PMID 12540572 DOI: 10.1128/Iai.71.2.904-909.2003 |
0.607 |
|
| 2002 |
Speert DP. Advances in Burkholderia cepacia complex Paediatric Respiratory Reviews. 3: 230-235. PMID 12376059 DOI: 10.1016/S1526-0542(02)00185-9 |
0.421 |
|
| 2002 |
Speert DP, Campbell ME, Henry DA, Milner R, Taha F, Gravelle A, Davidson AG, Wong LT, Mahenthiralingam E. Epidemiology of Pseudomonas aeruginosa in cystic fibrosis in British Columbia, Canada. American Journal of Respiratory and Critical Care Medicine. 166: 988-93. PMID 12359659 DOI: 10.1164/Rccm.2203011 |
0.373 |
|
| 2002 |
Conway BA, Venu V, Speert DP. Biofilm formation and acyl homoserine lactone production in the Burkholderia cepacia complex. Journal of Bacteriology. 184: 5678-85. PMID 12270826 DOI: 10.1128/Jb.184.20.5678-5685.2002 |
0.356 |
|
| 2002 |
Speert DP. Molecular epidemiology of Pseudomonas aeruginosa. Frontiers in Bioscience : a Journal and Virtual Library. 7: e354-61. PMID 12165481 |
0.308 |
|
| 2002 |
Soni R, Marks G, Henry DA, Robinson M, Moriarty C, Parsons S, Taylor P, Mahenthiralingam E, Speert DP, Bye PT. Effect of Burkholderia cepacia infection in the clinical course of patients with cystic fibrosis: a pilot study in a Sydney clinic. Respirology (Carlton, Vic.). 7: 241-5. PMID 12153690 DOI: 10.1046/J.1440-1843.2002.00387.X |
0.401 |
|
| 2002 |
Hirakata Y, Srikumar R, Poole K, Gotoh N, Suematsu T, Kohno S, Kamihira S, Hancock RE, Speert DP. Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa. The Journal of Experimental Medicine. 196: 109-18. PMID 12093875 DOI: 10.1084/Jem.20020005 |
0.382 |
|
| 2002 |
Vandamme P, Henry D, Coenye T, Nzula S, Vancanneyt M, LiPuma JJ, Speert DP, Govan JR, Mahenthiralingam E. Burkholderia anthina sp. nov. and Burkholderia pyrrocinia, two additional Burkholderia cepacia complex bacteria, may confound results of new molecular diagnostic tools. Fems Immunology and Medical Microbiology. 33: 143-9. PMID 12052570 DOI: 10.1016/S0928-8244(02)00301-2 |
0.326 |
|
| 2002 |
Chu KK, Davidson DJ, Halsey TK, Chung JW, Speert DP. Differential persistence among genomovars of the Burkholderia cepacia complex in a murine model of pulmonary infection. Infection and Immunity. 70: 2715-20. PMID 11953418 DOI: 10.1128/Iai.70.5.2715-2720.2002 |
0.706 |
|
| 2002 |
Speert DP, Henry D, Vandamme P, Corey M, Mahenthiralingam E. Epidemiology of Burkholderia cepacia complex in patients with cystic fibrosis, Canada. Emerging Infectious Diseases. 8: 181-7. PMID 11897071 DOI: 10.3201/Eid0802.010163 |
0.406 |
|
| 2002 |
Greenberg D, Speert DP, Mahenthiralingam E, Henry DA, Campbell ME, Scheifele DW. Emergence of penicillin-nonsusceptible Streptococcus pneumoniae invasive clones in Canada. Journal of Clinical Microbiology. 40: 68-74. PMID 11773094 DOI: 10.1128/Jcm.40.1.68-74.2002 |
0.327 |
|
| 2001 |
Mahenthiralingam E, Vandamme P, Campbell ME, Henry DA, Gravelle AM, Wong LT, Davidson AG, Wilcox PG, Nakielna B, Speert DP. Infection with Burkholderia cepacia complex genomovars in patients with cystic fibrosis: virulent transmissible strains of genomovar III can replace Burkholderia multivorans. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 33: 1469-75. PMID 11588691 DOI: 10.1086/322684 |
0.397 |
|
| 2001 |
Chiu CH, Wong S, Hancock REW, Speert DP. Adherence of Burkholderia cepacia to respiratory tract epithelial cells and inhibition with dextrans Microbiology. 147: 2651-2658. PMID 11577144 DOI: 10.1099/00221287-147-10-2651 |
0.402 |
|
| 2001 |
Coenye T, Mahenthiralingam E, Henry D, LiPuma JJ, Laevens S, Gillis M, Speert DP, Vandamme P. Burkholderia ambifaria sp. nov., a novel member of the Burkholderia cepacia complex including biocontrol and cystic fibrosis-related isolates International Journal of Systematic and Evolutionary Microbiology. 51: 1481-1490. PMID 11491349 DOI: 10.1099/00207713-51-4-1481 |
0.399 |
|
| 2001 |
Chiu CH, Ostry A, Speert DP. Invasion of murine respiratory epithelial cells in vivo by Burkholderia cepacia Journal of Medical Microbiology. 50: 594-601. PMID 11444769 |
0.343 |
|
| 2001 |
Pollard AJ, Heale JP, Tsang A, Massing B, Speert DP. Nonopsonic phagocytosis of Pseudomonas aeruginosa: Insights from an infant with leukocyte adhesion deficiency Pediatric Infectious Disease Journal. 20: 452-454. PMID 11332677 DOI: 10.1097/00006454-200104000-00019 |
0.325 |
|
| 2001 |
Coenye T, LiPuma JJ, Henry D, Hoste B, Vandemeulebroeke K, Gillis M, Speert DP, Vandamme P. Burkholderia cepacia genomovar VI, a new member of the Burkholderia cepacia complex isolated from cystic fibrosis patients International Journal of Systematic and Evolutionary Microbiology. 51: 271-279. PMID 11321071 DOI: 10.1099/00207713-51-2-271 |
0.385 |
|
| 2001 |
Heale JP, Pollard AJ, Stokes RW, Simpson D, Tsang A, Massing B, Speert DP. Two distinct receptors mediate nonopsonic phagocytosis of different strains of Pseudomonas aeruginosa. The Journal of Infectious Diseases. 183: 1214-20. PMID 11262203 DOI: 10.1086/319685 |
0.338 |
|
| 2001 |
Henry DA, Mahenthiralingam E, Vandamme P, Coenye T, Speert DP. Phenotypic methods for determining genomovar status of the Burkholderia cepacia complex Journal of Clinical Microbiology. 39: 1073-1078. PMID 11230429 DOI: 10.1128/Jcm.39.3.1073-1078.2001 |
0.343 |
|
| 2001 |
Heale JP, Speert DP. Protein kinase C agonists enhance phagocytosis of P. aeruginosa by murine alveolar macrophages Journal of Leukocyte Biology. 69: 158-160. PMID 11200060 DOI: 10.1189/Jlb.69.1.158 |
0.313 |
|
| 2000 |
Campbell M, Mahenthiralingam E, Speert DP. Evaluation of random amplified polymorphic DNA typing of Pseudomonas aeruginosa Journal of Clinical Microbiology. 38: 4614-4615. PMID 11101604 DOI: 10.1128/Jcm.38.12.4614-4615.2000 |
0.309 |
|
| 2000 |
Cheung DOY, Halsey K, Speert DP. Role of pulmonary alveolar macrophages in defense of the lung against Pseudomonas aeruginosa Infection and Immunity. 68: 4585-4592. PMID 10899859 DOI: 10.1128/Iai.68.8.4585-4592.2000 |
0.348 |
|
| 2000 |
Simpson DA, Speert DP. RpmA is required for nonopsonic phagocytosis of Pseudomonas aeruginosa Infection and Immunity. 68: 2493-2502. PMID 10768936 DOI: 10.1128/Iai.68.5.2493-2502.2000 |
0.394 |
|
| 2000 |
Aaron SD, Ferris W, Henry DA, Speert DP, MacDonald NE. Multiple combination bactericidal antibiotic testing for patients with cystic fibrosis infected with Burkholderia cepacia American Journal of Respiratory and Critical Care Medicine. 161: 1206-1212. PMID 10764313 DOI: 10.1164/Ajrccm.161.4.9907147 |
0.385 |
|
| 2000 |
Vandamme P, Mahenthiralingam E, Holmes B, Coenye T, Hoste B, De Vos P, Henry D, Speert DP. Identification and population structure of Burkholderia stabilis sp. nov. (formerly Burkholderia cepacia genomovar IV). Journal of Clinical Microbiology. 38: 1042-7. PMID 10698993 DOI: 10.1128/Jcm.38.3.1042-1047.2000 |
0.329 |
|
| 2000 |
Hirakata Y, Finlay BB, Simpson DA, Kohno S, Kamihira S, Speert DP. Penetration of clinical isolates of Pseudomonas aeruginosa through MDCK epithelial cell monolayers Journal of Infectious Diseases. 181: 765-769. PMID 10669373 DOI: 10.1086/315276 |
0.397 |
|
| 2000 |
Mahenthiralingam E, Coenye T, Chung JW, Speert DP, Govan JR, Taylor P, Vandamme P. Diagnostically and experimentally useful panel of strains from the Burkholderia cepacia complex. Journal of Clinical Microbiology. 38: 910-3. PMID 10655415 DOI: 10.1128/Jcm.38.2.910-913.2000 |
0.57 |
|
| 1999 |
Speert DP, Steen B, Halsey K, Kwan E. A murine model for infection with Burkholderia cepacia with sustained persistence in the spleen Infection and Immunity. 67: 4027-4032. PMID 10417170 DOI: 10.1128/Iai.67.8.4027-4032.1999 |
0.442 |
|
| 1999 |
Bryan R, Feldman M, Jawetz SC, Rajan S, DiMango E, Tang HB, Scheffler L, Speert DP, Prince A. The effects of aerosolized dextran in a mouse model of Pseudomonas aeruginosa pulmonary infection Journal of Infectious Diseases. 179: 1449-1458. PMID 10228067 DOI: 10.1086/314755 |
0.373 |
|
| 1999 |
Henry D, Campbell M, McGimpsey C, Clarke A, Louden L, Burns JL, Roe MH, Vandamme P, Speert D. Comparison of Isolation Media for Recovery of Burkholderia cepacia Complex from Respiratory Secretions of Patients with Cystic Fibrosis Journal of Clinical Microbiology. 37: 1004-1007. DOI: 10.1128/Jcm.37.4.1004-1007.1999 |
0.337 |
|
| 1999 |
Speert DP, Simpson DA. Phagocytosis of Pseudomonas aeruginosa Advances in Cellular and Molecular Biology of Membranes and Organelles. 6: 159-172. DOI: 10.1016/S1874-5172(99)80010-8 |
0.423 |
|
| 1998 |
Feng W, Garrett H, Speert DP, King M. Improved clearability of cystic fibrosis sputum with dextran treatment in vitro American Journal of Respiratory and Critical Care Medicine. 157: 710-714. PMID 9517580 DOI: 10.1164/Ajrccm.157.3.9703059 |
0.344 |
|
| 1998 |
Speert DP. Group A streptococcal carriage: Can the troll be tamed? Canadian Journal of Infectious Diseases. 9: 205-206. DOI: 10.1093/Pch/3.4.229 |
0.334 |
|
| 1997 |
Woods DE, Lam JS, Paranchych W, Speert DP, Campbell M, Godfrey AJ. Correlation of Pseudomonas aeruginosa virulence factors from clinical and environmental isolates with pathogenicity in the neutropenic mouse Canadian Journal of Microbiology. 43: 541-551. PMID 9226874 DOI: 10.1139/M97-077 |
0.367 |
|
| 1997 |
Mahenthiralingam E, Simpson DA, Speert DP. Identification and characterization of a novel DNA marker associated with epidemic Burkholderia cepacia strains recovered from patients with cystic fibrosis Journal of Clinical Microbiology. 35: 808-816. PMID 9157133 DOI: 10.1128/Jcm.35.4.808-816.1997 |
0.385 |
|
| 1997 |
LiPuma J, Henry D, Mehar F, Speert D, Saiman L. Misidentification of Burkholderia Cepacia. † 1810 Pediatric Research. 41: 304-304. DOI: 10.1203/00006450-199704001-01829 |
0.351 |
|
| 1996 |
Barghouthi S, Guerdoud LM, Speert DP. Inhibition by dextran of Pseudomonas aeruginosa adherence to epithelial cells American Journal of Respiratory and Critical Care Medicine. 154: 1788-1793. PMID 8970372 DOI: 10.1164/Ajrccm.154.6.8970372 |
0.388 |
|
| 1996 |
Mahenthiralingam E, Campbell ME, Henry DA, Speert DP. Epidemiology of Burkholderia cepacia infection in patients with cystic fibrosis: analysis by randomly amplified polymorphic DNA fingerprinting. Journal of Clinical Microbiology. 34: 2914-20. PMID 8940422 DOI: 10.1128/Jcm.34.12.2914-2920.1996 |
0.424 |
|
| 1996 |
Mahenthiralingam E, Campbell ME, Foster J, Lam JS, Speert DP. Random amplified polymorphic DNA typing of Pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis. Journal of Clinical Microbiology. 34: 1129-35. PMID 8727889 DOI: 10.1128/Jcm.34.5.1129-1135.1996 |
0.444 |
|
| 1995 |
Mahenthiralingam E, Speert DP. Nonopsonic phagocytosis of Pseudomonas aeruginosa by macrophages and polymorphonuclear leukocytes requires the presence of the bacterial flagellum Infection and Immunity. 63: 4519-4523. PMID 7591095 DOI: 10.1128/Iai.63.11.4519-4523.1995 |
0.355 |
|
| 1995 |
Burdge DR, Noble MA, Campbell ME, Krell VL, Speert DP. Xanthomonas maltophilia misidentified as Pseudomonas cepacia in cultures of sputum from patients with cystic fibrosis: a diagnostic pitfall with major clinical implications. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 20: 445-8. PMID 7537977 DOI: 10.1093/Clinids/20.2.445 |
0.424 |
|
| 1994 |
Mahenthiralingam E, Campbell ME, Speert DP. Nonmotility and phagocytic resistance of Pseudomonas aeruginosa isolates from chronically colonized patients with cystic fibrosis. Infection and Immunity. 62: 596-605. PMID 8300217 DOI: 10.1128/Iai.62.2.596-605.1994 |
0.432 |
|
| 1994 |
Speert DP, Bond M, Woodman RC, Curnutte JT. Infection with pseudomonas cepacia in chronic granulomatous disease: Role of nonoxidative killing by neutrophils in host defense Journal of Infectious Diseases. 170: 1524-1531. PMID 7527826 DOI: 10.1093/Infdis/170.6.1524 |
0.382 |
|
| 1993 |
Speert DP, Campbell ME, Davidson AG, Wong LT. Pseudomonas aeruginosa colonization of the gastrointestinal tract in patients with cystic fibrosis. The Journal of Infectious Diseases. 167: 226-9. PMID 8418173 DOI: 10.1093/Infdis/167.1.226 |
0.375 |
|
| 1993 |
Speert DP. Phagocytosis of Pseudomonas aeruginosa by macrophages: receptor-ligand interactions Trends in Microbiology. 1: 217-221. PMID 8137118 DOI: 10.1016/0966-842X(93)90135-E |
0.318 |
|
| 1992 |
Speert DP, Gordon S. Phagocytosis of unopsonized Pseudomonas aeruginosa by murine macrophages is a two-step process requiring glucose Journal of Clinical Investigation. 90: 1085-1092. PMID 1522217 DOI: 10.1172/Jci115924 |
0.355 |
|
| 1991 |
Phillips P, Forbes JC, Speert DP. Disseminated infection with Pseudallescheria boydii in a patient with chronic granulomatous disease: Response to gamma–interferon plus antifungal chemotherapy Pediatric Infectious Disease Journal. 10: 536-539. PMID 1908570 DOI: 10.1097/00006454-199107000-00011 |
0.324 |
|
| 1991 |
Bayer AS, Speert DP, Park S, Tu J, Witt M, Nast CC, Norman DC. Functional role of mucoid exopolysaccharide (alginate) in antibiotic-induced and polymorphonuclear leukocyte-mediated killing of Pseudomonas aeruginosa Infection and Immunity. 59: 302-308. PMID 1898898 DOI: 10.1128/Iai.59.1.302-308.1991 |
0.342 |
|
| 1991 |
Speert DP, Thorson L. Suppression by human recombinant gamma interferon of in vitro macrophage nonopsonic and opsonic phagocytosis and killing Infection and Immunity. 59: 1893-1898. PMID 1645327 DOI: 10.1128/Iai.59.6.1893-1898.1991 |
0.31 |
|
| 1990 |
Bayer AS, Eftekhar F, Tu J, Nast CC, Speert DP. Oxygen-dependent up-regulation of mucoid exopolysaccharide (alginate) production in Pseudomonas aeruginosa Infection and Immunity. 58: 1344-1349. PMID 2139011 DOI: 10.1128/Iai.58.5.1344-1349.1990 |
0.345 |
|
| 1990 |
Speert DP, Farmer SW, Campbell ME, Musser JM, Selander RK, Kuo S. Conversion of Pseudomonas aeruginosa to the phenotype characteristic of strains from patients with cystic fibrosis. Journal of Clinical Microbiology. 28: 188-94. PMID 2107198 DOI: 10.1128/Jcm.28.2.188-194.1990 |
0.448 |
|
| 1989 |
Speert DP, Davidson AGF, Wong LTK, Paranchych W. Communicability of Pseudomonas infections in patients with cystic fibrosis The Journal of Pediatrics. 114: 1068-1069. PMID 2723904 DOI: 10.1016/S0022-3476(89)80476-7 |
0.394 |
|
| 1989 |
Speert DP, Campbell ME, Farmer SW, Volpel K, Joffe AM, Paranchych W. Use of a pilin gene probe to study molecular epidemiology of Pseudomonas aeruginosa. Journal of Clinical Microbiology. 27: 2589-93. PMID 2572604 DOI: 10.1128/Jcm.27.11.2589-2593.1989 |
0.384 |
|
| 1989 |
Speert DP. Prevention of severe lower respiratory infections in patients with cystic fibrosis Seminars in Respiratory Infections. 4: 266-271. PMID 2516638 |
0.303 |
|
| 1988 |
Eftekhar F, Speert DP. Alginase treatment of mucoid Pseudomonas aeruginosa enhances phagocytosis by human monocyte-derived macrophages Infection and Immunity. 56: 2788-2793. PMID 3139564 DOI: 10.1128/Iai.56.11.2788-2793.1988 |
0.436 |
|
| 1988 |
Speert DP, Wright SD, Silverstein SC, Mah B. Functional characterization of macrophage receptors for in vitro phagocytosis of unopsonized Pseudomonas aeruginosa. The Journal of Clinical Investigation. 82: 872-9. PMID 3138287 DOI: 10.1172/Jci113692 |
0.314 |
|
| 1988 |
Lam JS, MacDonald LA, Kropinski AM, Speert DP. Characterization of non-typable strains of Pseudomonas aeruginosa from cystic fibrosis patients by means of monoclonal antibodies and SDS-polyacrylamide gel electrophoresis Serodiagnosis and Immunotherapy in Infectious Disease. 2: 365-374. DOI: 10.1016/0888-0786(88)90064-9 |
0.353 |
|
| 1987 |
Speert DP, Dimmick JE, Pier GB, Saunders JM, Hancock REW, Kelly N. An immunohistological evaluation of Pseudomonas aeruginosa pulmonary infection in two patients with cystic fibrosis Pediatric Research. 22: 743-747. PMID 3431961 DOI: 10.1203/00006450-198712000-00026 |
0.393 |
|
| 1987 |
Pier GB, Saunders JM, Ames P, Edwards MS, Auerbach H, Goldfarb J, Speert DP, Hurwitch S. Opsonophagocytic killing antibody to Pseudomonas aeruginosa mucoid exopolysaccharide in older noncolonized patients with cystic fibrosis New England Journal of Medicine. 317: 793-798. PMID 2957591 DOI: 10.1056/Nejm198709243171303 |
0.325 |
|
| 1987 |
Cabral DA, Loh BA, Speert DP. Mucoid pseudomonas aeruginosa resists nonopsonic phagocytosis by human neutrophils and macrophages Pediatric Research. 22: 429-431. PMID 2891100 DOI: 10.1203/00006450-198710000-00013 |
0.422 |
|
| 1987 |
Speert DP, Campbell ME. Hospital epidemiology of Pseudomonas aeruginosa from patients with cystic fibrosis. The Journal of Hospital Infection. 9: 11-21. PMID 2880893 DOI: 10.1016/0195-6701(87)90089-2 |
0.363 |
|
| 1986 |
Pier GB, Desjardins D, Aguilar T, Barnard M, Speert DP. Polysaccharide surface antigens expressed by nonmucoid isolates of Pseudomonas aeruginosa from cystic fibrosis patients Journal of Clinical Microbiology. 24: 189-196. PMID 2943759 DOI: 10.1128/Jcm.24.2.189-196.1986 |
0.421 |
|
| 1986 |
Speert DP, Loh BA, Cabral DA, Salit IE. Nonopsonic phagocytosis of nonmucoid Pseudomonas aeruginosa by human neutrophils and monocyte-derived macrophages is correlated with bacterial piliation and hydrophobicity Infection and Immunity. 53: 207-212. PMID 2873104 DOI: 10.1128/Iai.53.1.207-212.1986 |
0.396 |
|
| 1985 |
Burdge DR, Scheifele D, Speert DP. Serious Pasteurella multocida Infections From Lion and Tiger Bites Jama: the Journal of the American Medical Association. 253: 3296-3297. PMID 3999316 DOI: 10.1001/Jama.1985.03350460096030 |
0.302 |
|
| 1985 |
Speert DP, Loh BA, Cabral DA, Eftekhar F. Opsonin-independent phagocytosis of Pseudomonas aeruginosa Antibiotics and Chemotherapy. 36: 88-94. PMID 3923915 DOI: 10.1159/000410474 |
0.385 |
|
| 1984 |
Hancock REW, Mouat ECA, Speert DP. Quantitation and identification of antibodies to outer-membrane proteins of Pseudomonas aeruginosa in sera of patients with cystic fibrosis Journal of Infectious Diseases. 149: 220-226. PMID 6421943 DOI: 10.1093/Infdis/149.2.220 |
0.314 |
|
| 1984 |
Speert DP, Eftekhar F, Puterman ML. Nonopsonic phagocytosis of strains of Pseudomonas aeruginosa from cystic fibrosis patients Infection and Immunity. 43: 1006-1011. PMID 6421734 DOI: 10.1128/Iai.43.3.1006-1011.1984 |
0.432 |
|
| 1984 |
Speert DP, Lawton D, Mutharia LM. Antibody to pseudomonas aeruginosa mucoid exopolysaccharide and to sodium alginate in cystic fibrosis serum Pediatric Research. 18: 431-433. PMID 6233529 DOI: 10.1203/00006450-198405000-00008 |
0.33 |
|
| 1983 |
Hancock REW, Mutharia LM, Chan L, Darveau RP, Speert DP, Pier GB. Pseudomonas aeruginosa isolates from patients with cystic fibrosis: A class of serum-sensitive, nontypable strains deficient in lipopolysaccharide O side chains Infection and Immunity. 42: 170-177. PMID 6413410 DOI: 10.1128/Iai.42.1.170-177.1983 |
0.367 |
|
| 1982 |
Speert DP, Lawton D, Damm S. Communicability of Pseudomonas aeruginosa in a cystic fibrosis summer camp The Journal of Pediatrics. 101: 227-229. PMID 6808106 DOI: 10.1016/S0022-3476(82)80127-3 |
0.343 |
|
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