Peter L. Carlen - Publications

Affiliations: 
Biomedical Engineering University of Toronto, Toronto, ON, Canada 
Area:
Biomedical Engineering, Neuroscience Biology

228 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Moradi Chameh H, Rich S, Wang L, Chen FD, Zhang L, Carlen PL, Tripathy SJ, Valiante TA. Author Correction: Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences. Nature Communications. 13: 1689. PMID 35332144 DOI: 10.1038/s41467-022-29220-9  0.556
2021 Breton VL, Aquilino MS, Repudi S, Saleem A, Mylvaganam S, Abu-Swai S, Bardakjian BL, Aqeilan RI, Carlen PL. Altered neocortical oscillations and cellular excitability in an in vitro Wwox knockout mouse model of epileptic encephalopathy. Neurobiology of Disease. 160: 105529. PMID 34634460 DOI: 10.1016/j.nbd.2021.105529  0.313
2021 Liu H, Tufa U, Zahra A, Chow J, Sivanenthiran N, Cheng C, Liu Y, Cheung P, Lim S, Jin Y, Mao M, Sun Y, Wu C, Wennberg R, Bardakjian B, ... Carlen PL, et al. Electrographic Features of Spontaneous Recurrent Seizures in a Mouse Model of Extended Hippocampal Kindling. Cerebral Cortex Communications. 2: tgab004. PMID 34296153 DOI: 10.1093/texcom/tgab004  0.303
2021 Moradi Chameh H, Rich S, Wang L, Chen FD, Zhang L, Carlen PL, Tripathy SJ, Valiante TA. Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences. Nature Communications. 12: 2497. PMID 33941783 DOI: 10.1038/s41467-021-22741-9  0.554
2020 Rafiee M, Patel K, Groppe DM, Andrade DM, Bercovici E, Bui E, Carlen PL, Reid A, Tai P, Weaver D, Wennberg R, Valiante TA. Daily listening to Mozart reduces seizures in individuals with epilepsy: A randomized control study. Epilepsia Open. 5: 285-294. PMID 32524054 DOI: 10.1002/epi4.12400  0.582
2019 Lertwittayanon W, Devinsky O, Carlen PL. Cardiorespiratory depression from brainstem seizure activity in freely moving rats. Neurobiology of Disease. 104628. PMID 31669732 DOI: 10.1016/J.Nbd.2019.104628  0.382
2019 Jacobs D, Liu YH, Hilton T, Del Campo M, Carlen PL, Bardakjian BL. Classification of Scalp EEG States Prior to Clinical Seizure Onset. Ieee Journal of Translational Engineering in Health and Medicine. 7: 2000203. PMID 31497409 DOI: 10.1109/Jtehm.2019.2926257  0.333
2019 Kalitzin S, Petkov G, Suffczynski P, Grigorovsky V, Bardakjian BL, da Silva FL, Carlen PL. Epilepsy as a manifestation of a multistate network of oscillatory systems. Neurobiology of Disease. 104488. PMID 31181283 DOI: 10.1016/J.Nbd.2019.104488  0.379
2019 Kassiri H, Der Chen F, Salam MT, Chang M, Vatankhahghadim B, Carlen P, Valiante TA, Genov R. Arbitrary-Waveform Electro-Optical Intracranial Neurostimulator with Load-Adaptive High-Voltage Compliance. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. PMID 30802868 DOI: 10.1109/Tnsre.2019.2900455  0.585
2019 Chang M, Dufour S, Carlen PL, Valiante TA. Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue. Journal of Visualized Experiments : Jove. PMID 30735161 DOI: 10.3791/57952  0.627
2019 Gondard E, Teves L, Wang L, McKinnon C, Hamani C, Kalia SK, Carlen PL, Tymianski M, Lozano AM. Deep Brain Stimulation rescues memory and synaptic activity in a rat model of global ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30696731 DOI: 10.1523/Jneurosci.1222-18.2019  0.316
2019 Wennberg R, Maurice C, Carlen PL, Garcia Dominguez L. Pilomotor seizures marked by infraslow activity and acetazolamide responsiveness. Annals of Clinical and Translational Neurology. 6: 167-173. PMID 30656195 DOI: 10.1002/Acn3.695  0.371
2019 Bazzigaluppi P, Dorr A, Mester J, Koletar M, Carlen P, Stefanovic B. Abstract 158: Optogenetic Theta-band Activation of Pyramidal Neurons Elicits Peri-infarct Spreading Depolarizations in the ET-1 Rat Model of Focal Cortical Ischemia Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.158  0.328
2018 Song H, Mylvaganam SM, Wang J, Mylvaganam SMK, Wu C, Carlen PL, Eubanks JH, Feng J, Zhang L. Contributions of the Hippocampal CA3 Circuitry to Acute Seizures and Hyperexcitability Responses in Mouse Models of Brain Ischemia. Frontiers in Cellular Neuroscience. 12: 278. PMID 30210302 DOI: 10.3389/Fncel.2018.00278  0.437
2018 Jacobs D, Hilton T, Del Campo M, Carlen PL, Bardakjian BL. Classification of Pre-Clinical Seizure States using Scalp EEG Cross-Frequency Coupling Features. Ieee Transactions On Bio-Medical Engineering. PMID 29993471 DOI: 10.1109/Tbme.2018.2797919  0.337
2017 Bazzigaluppi P, Ebrahim Amini A, Weisspapir I, Stefanovic B, Carlen PL. Hungry Neurons: Metabolic Insights on Seizure Dynamics. International Journal of Molecular Sciences. 18. PMID 29143800 DOI: 10.3390/Ijms18112269  0.396
2017 Chang M, Dian JA, Dufour S, Wang L, Moradi-Chameh H, Ramani M, Zhang L, Carlen PL, Womelsdorf T, Valiante TA. Brief activation of GABAergic interneurons initiates the transition to ictal events through post-inhibitory rebound excitation. Neurobiology of Disease. PMID 29024712 DOI: 10.1016/J.Nbd.2017.10.007  0.602
2017 Aquilino MS, Whyte-Fagundes P, Zoidl G, Carlen PL. Pannexin-1 Channels in Epilepsy. Neuroscience Letters. PMID 28886985 DOI: 10.1016/J.Neulet.2017.09.004  0.376
2017 Salam MT, Montandon G, Genov R, Devinsky O, Del Campo M, Carlen PL. Mortality with brainstem seizures from focal 4-aminopyridine-induced recurrent hippocampal seizures. Epilepsia. PMID 28691204 DOI: 10.1111/Epi.13846  0.38
2017 Kassiri H, Salam MT, Pazhouhandeh MR, Soltani N, Velazquez JLP, Carlen P, Genov R. Rail-to-Rail-Input Dual-Radio 64-Channel Closed-Loop Neurostimulator Ieee Journal of Solid-State Circuits. 52: 2793-2810. DOI: 10.1109/Jssc.2017.2749426  0.323
2016 Bazzigaluppi P, Weisspapir I, Stefanovic B, Leybaert L, Carlen PL. Astrocytic gap junction blockade markedly increases extracellular potassium without causing seizures in the mouse neocortex. Neurobiology of Disease. PMID 28007587 DOI: 10.1016/J.Nbd.2016.12.017  0.33
2016 Li C, Jacobs D, Hilton T, Campo MD, Chinvarun Y, Carlen PL, Bardakjian BL. Epileptogenic Source Imaging Using Cross-Frequency Coupled Signals From Scalp EEG. Ieee Transactions On Bio-Medical Engineering. 63: 2607-2618. PMID 27875126 DOI: 10.1109/Tbme.2016.2613936  0.353
2016 Machado R, Soltani N, Dufour S, Salam MT, Carlen PL, Genov R, Thompson M. Biofouling-Resistant Impedimetric Sensor for Array High-Resolution Extracellular Potassium Monitoring in the Brain. Biosensors. 6. PMID 27754393 DOI: 10.3390/Bios6040053  0.321
2016 Sigal I, Koletar MM, Ringuette D, Gad R, Jeffrey M, Carlen PL, Stefanovic B, Levi O. Imaging brain activity during seizures in freely behaving rats using a miniature multi-modal imaging system. Biomedical Optics Express. 7: 3596-3609. PMID 27699123 DOI: 10.1364/Boe.7.003596  0.306
2016 Wang L, Dufour S, Valiante TA, Carlen PL. Extracellular Potassium and Seizures: Excitation, Inhibition and the Role of Ih. International Journal of Neural Systems. 1650044. PMID 27464853 DOI: 10.1142/S0129065716500441  0.629
2016 Krawczyk M, Ramani M, Dian J, Florez CM, Mylvaganam S, Brien J, Reynolds J, Kapur B, Zoidl G, Poulter MO, Carlen PL. Hippocampal Hyperexcitability in Fetal Alcohol Spectrum Disorder: Pathological Sharp Waves and Excitatory/Inhibitory Synaptic Imbalance. Experimental Neurology. PMID 26996134 DOI: 10.1016/J.Expneurol.2016.03.013  0.422
2016 Ramani M, Mylvaganam S, Krawczyk M, Wang L, Zoidl C, Brien J, Reynolds JN, Kapur B, Poulter MO, Zoidl G, Carlen PL. Differential expression of astrocytic connexins in a mouse model of prenatal alcohol exposure. Neurobiology of Disease. PMID 26951949 DOI: 10.1016/J.Nbd.2016.02.022  0.328
2016 Jalini S, Ye H, Tonkikh AA, Charlton MP, Carlen PL. Raised Intracellular Calcium Contributes to Ischemia-Induced Depression of Evoked Synaptic Transmission. Plos One. 11: e0148110. PMID 26934214 DOI: 10.1371/Journal.Pone.0148110  0.5
2016 Cotic M, Chinvarun Y, Del Campo M, Carlen PL, Bardakjian BL. Spatial Coherence Profiles of Ictal High-Frequency Oscillations Correspond to Those of Interictal Low-Frequency Oscillations in the ECoG of Epileptic Patients. Ieee Transactions On Bio-Medical Engineering. 63: 76-85. PMID 25561587 DOI: 10.1109/Tbme.2014.2386791  0.721
2016 Ringuette D, Carlen PL, Levi O. Multi-modality optical imaging of temporal and spatial dynamics during in vivo seizure-like activity Brain. DOI: 10.1364/Brain.2016.Bm4D.3  0.341
2015 Florez CM, Lukankin V, Sugumar S, McGinn R, Zhang ZJ, Zhang L, Carlen PL. Hypoglycemia-induced alterations in hippocampal intrinsic rhythms: Decreased inhibition, increased excitation, seizures and spreading depression. Neurobiology of Disease. 82: 213-225. PMID 26093168 DOI: 10.1016/J.Nbd.2015.06.005  0.373
2015 Guirgis M, Chinvarun Y, Del Campo M, Carlen PL, Bardakjian BL. Defining regions of interest using cross-frequency coupling in extratemporal lobe epilepsy patients. Journal of Neural Engineering. 12: 026011. PMID 25768723 DOI: 10.1088/1741-2560/12/2/026011  0.363
2015 Cotic M, Zalay OC, Chinvarun Y, del Campo M, Carlen PL, Bardakjian BL. Mapping the coherence of ictal high frequency oscillations in human extratemporal lobe epilepsy. Epilepsia. 56: 393-402. PMID 25630492 DOI: 10.1111/Epi.12918  0.741
2015 Shulyzki R, Abdelhalim K, Bagheri A, Salam MT, Florez CM, Velazquez JL, Carlen PL, Genov R. 320-channel active probe for high-resolution neuromonitoring and responsive neurostimulation. Ieee Transactions On Biomedical Circuits and Systems. 9: 34-49. PMID 25486647 DOI: 10.1109/Tbcas.2014.2312552  0.322
2015 Bazzigaluppi P, Dufour S, Carlen PL. Wide field fluorescent imaging of extracellular spatiotemporal potassium dynamics in vivo. Neuroimage. 104: 110-6. PMID 25312775 DOI: 10.1016/J.Neuroimage.2014.10.012  0.32
2015 Florez CM, McGinn RJ, Lukankin V, Marwa I, Sugumar S, Dian J, Hazrati LN, Carlen PL, Zhang L, Valiante TA. In vitro recordings of human neocortical oscillations. Cerebral Cortex (New York, N.Y. : 1991). 25: 578-97. PMID 24046077 DOI: 10.1093/Cercor/Bht235  0.623
2015 Kassiri H, Salam MT, Der Chen F, Vatankhahghadim B, Soltani N, Chang M, Carlen P, Valiante TA, Genov R. Inductively powered arbitrary-waveform adaptive-supply electro-optical neurostimulator Ieee Biomedical Circuits and Systems Conference: Engineering For Healthy Minds and Able Bodies, Biocas 2015 - Proceedings. DOI: 10.1109/BioCAS.2015.7348349  0.544
2014 Cotic M, Chinvarun Y, Guirgis M, Carlen PL, Bardakjian BL. Gamma (30-80Hz) bicoherence distinguishes seizures in the human epileptic brain. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2014: 4455-8. PMID 25570981 DOI: 10.1109/EMBC.2014.6944613  0.727
2014 Mansouri A, Fallah A, McAndrews MP, Cohn M, Mayor D, Andrade D, Carlen P, Del Campo JM, Tai P, Wennberg RA, Valiante TA. Neurocognitive and Seizure Outcomes of Selective Amygdalohippocampectomy versus Anterior Temporal Lobectomy for Mesial Temporal Lobe Epilepsy. Epilepsy Research and Treatment. 2014: 306382. PMID 25349728 DOI: 10.1155/2014/306382  0.603
2014 Goncharenko K, Eftekharpour E, Velumian AA, Carlen PL, Fehlings MG. Changes in gap junction expression and function following ischemic injury of spinal cord white matter. Journal of Neurophysiology. 112: 2067-75. PMID 25080569 DOI: 10.1152/Jn.00037.2013  0.39
2014 Gabran SR, Salam MT, Dian J, El-Hayek Y, Perez Velazquez JL, Genov R, Carlen PL, Salama MM, Mansour RR. 3-D flexible nano-textured high-density microelectrode arrays for high-performance neuro-monitoring and neuro-stimulation. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 22: 1072-82. PMID 24876130 DOI: 10.1109/Tnsre.2014.2322077  0.754
2014 Mylvaganam S, Ramani M, Krawczyk M, Carlen PL. Roles of gap junctions, connexins, and pannexins in epilepsy. Frontiers in Physiology. 5: 172. PMID 24847276 DOI: 10.3389/Fphys.2014.00172  0.419
2014 Guirgis M, Serletis D, Zhang J, Florez C, Dian JA, Carlen PL, Bardakjian BL. Classification of Multiple Seizure-Like States in Three Different Rodent Models of Epileptogenesis. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 22: 21-32. PMID 23771347 DOI: 10.1109/Tnsre.2013.2267543  0.381
2014 Maheandiran M, Mylvaganam S, Wu C, El-Hayek Y, Sugumar S, Vukelich R, Campo Md, Giacca A, Zhang L, Carlen PL. 3. Severe hypoglycemia in juvenile diabetic rats: Presence and severity of seizures predictive for mortality Clinical Neurophysiology. 125: e10. DOI: 10.1016/J.Clinph.2013.09.016  0.767
2014 Valiante TA, Carlen PL. Electrophysiological Mechanisms of Network Control: Bursting in the Brain-From Cells to Networks Neuronal Networks in Brain Function, Cns Disorders, and Therapeutics. 121-133. DOI: 10.1016/B978-0-12-415804-7.00009-5  0.503
2013 Maheandiran M, Mylvaganam S, Wu C, El-Hayek Y, Sugumar S, Hazrati L, del Campo M, Giacca A, Zhang L, Carlen PL. Severe hypoglycemia in a juvenile diabetic rat model: presence and severity of seizures are associated with mortality. Plos One. 8: e83168. PMID 24386156 DOI: 10.1371/Journal.Pone.0083168  0.781
2013 Gabran SR, Salam MT, Dian J, El-Hayek Y, Perez Velazquez JL, Genov R, Carlen PL, Salama MM, Mansour RR. High-density intracortical microelectrode arrays with multiple metallization layers for fine-resolution neuromonitoring and neurostimulation. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 21: 869-79. PMID 24122564 DOI: 10.1109/Tnsre.2013.2279403  0.754
2013 Cotic M, Zalay O, Carlen PL, Chinvarun Y, Bardakjian BL. Synchrony of high frequency oscillations in the human epileptic brain. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 5582-5. PMID 24111002 DOI: 10.1109/EMBC.2013.6610815  0.732
2013 El-Hayek YH, Wu C, Ye H, Wang J, Carlen PL, Zhang L. Hippocampal excitability is increased in aged mice. Experimental Neurology. 247: 710-9. PMID 23510762 DOI: 10.1016/J.Expneurol.2013.03.012  0.79
2013 Serletis D, Carlen PL, Valiante TA, Bardakjian BL. Phase synchronization of neuronal noise in mouse hippocampal epileptiform dynamics. International Journal of Neural Systems. 23: 1250033. PMID 23273129 DOI: 10.1142/S0129065712500335  0.616
2013 Sutton AC, Yu W, Calos ME, Mueller LE, Berk M, Shim J, Molho ES, Brotchie JM, Carlen PL, Shin DS. Elevated potassium provides an ionic mechanism for deep brain stimulation in the hemiparkinsonian rat. The European Journal of Neuroscience. 37: 231-41. PMID 23121286 DOI: 10.1111/Ejn.12040  0.344
2013 Maheandiran M, Mylvaganam S, Wu C, El-Hayek Y, Sugumar S, Hazrati L, Campo Md, Giacca A, Zhang L, Carlen PL. Effects of diabetes and seizures on neuronal damage. Plos One. DOI: 10.1371/Journal.Pone.0083168.G008  0.776
2013 Cotic M, Chinvarun Y, Carlen PL, Bardakjian BL. Spatial coherence patterns of fast ictal activities coincide with those of slow interictal oscillations in the human brain International Ieee/Embs Conference On Neural Engineering, Ner. 387-390. DOI: 10.1109/NER.2013.6695953  0.731
2013 Carlen P, Zhang Z, Koifman J, Shin D, Ye H, Florez C, Zhang L, Valiante T. 8. Transition into and out of a seizure in the hippocampal CA3 region: A failure of presynaptic release Clinical Neurophysiology. 124: e3-e4. DOI: 10.1016/J.Clinph.2012.08.046  0.699
2012 Serletis D, Bardakjian BL, Valiante TA, Carlen PL. Complexity and multifractality of neuronal noise in mouse and human hippocampal epileptiform dynamics. Journal of Neural Engineering. 9: 056008. PMID 22929878 DOI: 10.1088/1741-2560/9/5/056008  0.603
2012 Kang EE, Zalay OC, Serletis D, Carlen PL, Bardakjian BL. Markers of pathological excitability derived from principal dynamic modes of hippocampal neurons. Journal of Neural Engineering. 9: 056004. PMID 22871606 DOI: 10.1088/1741-2560/9/5/056004  0.591
2012 Carlen PL. Curious and contradictory roles of glial connexins and pannexins in epilepsy. Brain Research. 1487: 54-60. PMID 22796594 DOI: 10.1016/J.Brainres.2012.06.059  0.417
2012 Zhang ZJ, Koifman J, Shin DS, Ye H, Florez CM, Zhang L, Valiante TA, Carlen PL. Transition to seizure: ictal discharge is preceded by exhausted presynaptic GABA release in the hippocampal CA3 region. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2499-512. PMID 22396423 DOI: 10.1523/Jneurosci.4247-11.2012  0.698
2012 Ye H, Cotic M, Fehlings MG, Carlen PL. Influence of cellular properties on the electric field distribution around a single cell Progress in Electromagnetics Research B. 141-161. DOI: 10.2528/Pierb11122705  0.756
2011 Kang EE, Zalay OC, El Beheiry H, Wong J, del Campo M, Carlen PL, Bardakijan BL. Spectral features of electroencephalogram in characterizing various brain states under anesthesia. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 3099-102. PMID 22254995 DOI: 10.1109/IEMBS.2011.6090846  0.519
2011 Cotic M, Zalay O, Valiante T, Carlen PL, Bardakjian BL. Frequency interactions in human epileptic brain. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 2057-60. PMID 22254741 DOI: 10.1109/IEMBS.2011.6090380  0.783
2011 Zhang ZJ, Valiante TA, Carlen PL. Transition to seizure: From " macro" - to " micro" -mysteries Epilepsy Research. 97: 290-299. PMID 22075227 DOI: 10.1016/J.Eplepsyres.2011.09.025  0.636
2011 Shin DS, Yu W, Sutton A, Calos M, Puil E, Carlen PL. Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity. Epilepsia. 52: 2084-93. PMID 21906050 DOI: 10.1111/J.1528-1167.2011.03260.X  0.682
2011 Cotic M, Chiu AW, Jahromi SS, Carlen PL, Bardakjian BL. Common time-frequency analysis of local field potential and pyramidal cell activity in seizure-like events of the rat hippocampus. Journal of Neural Engineering. 8: 046024. PMID 21712570 DOI: 10.1088/1741-2560/8/4/046024  0.747
2011 El-Hayek YH, Wu C, Chen R, Al-Sharif AR, Huang S, Patel N, Du C, Ruff CA, Fehlings MG, Carlen PL, Zhang L. Acute postischemic seizures are associated with increased mortality and brain damage in adult mice. Cerebral Cortex (New York, N.Y. : 1991). 21: 2863-75. PMID 21531782 DOI: 10.1093/Cercor/Bhr080  0.793
2011 Chiu AW, Derchansky M, Cotic M, Carlen PL, Turner SO, Bardakjian BL. Wavelet-based Gaussian-mixture hidden Markov model for the detection of multistage seizure dynamics: a proof-of-concept study. Biomedical Engineering Online. 10: 29. PMID 21504608 DOI: 10.1186/1475-925X-10-29  0.736
2011 Serletis D, Zalay OC, Valiante TA, Bardakjian BL, Carlen PL. Complexity in neuronal noise depends on network interconnectivity. Annals of Biomedical Engineering. 39: 1768-78. PMID 21347547 DOI: 10.1007/S10439-011-0281-X  0.614
2011 Shin DS, Yu W, Sutton A, Calos M, Carlen PL. Elevated potassium elicits recurrent surges of large GABAA-receptor-mediated post-synaptic currents in hippocampal CA3 pyramidal neurons. Journal of Neurophysiology. 105: 1185-98. PMID 21209355 DOI: 10.1152/Jn.00770.2010  0.367
2011 Ye H, Cotic M, Fehlings MG, Carlen PL. Transmembrane potential generated by a magnetically induced transverse electric field in a cylindrical axonal model. Medical & Biological Engineering & Computing. 49: 107-19. PMID 21063912 DOI: 10.1007/S11517-010-0704-0  0.74
2010 Shahrokhi F, Abdelhalim K, Serletis D, Carlen PL, Genov R. The 128-channel fully differential digital integrated neural recording and stimulation interface. Ieee Transactions On Biomedical Circuits and Systems. 4: 149-61. PMID 23853339 DOI: 10.1109/Tbcas.2010.2041350  0.312
2010 Hamani C, Dubiela FP, Soares JC, Shin D, Bittencourt S, Covolan L, Carlen PL, Laxton AW, Hodaie M, Stone SS, Ha Y, Hutchison WD, Lozano AM, Mello LE, Oliveira MG. Anterior thalamus deep brain stimulation at high current impairs memory in rats. Experimental Neurology. 225: 154-62. PMID 20558163 DOI: 10.1016/J.Expneurol.2010.06.007  0.321
2010 Zalay OC, Serletis D, Carlen PL, Bardakjian BL. System characterization of neuronal excitability in the hippocampus and its relevance to observed dynamics of spontaneous seizure-like transitions. Journal of Neural Engineering. 7: 036002. PMID 20404398 DOI: 10.1088/1741-2560/7/3/036002  0.436
2010 Bell SH, Stade B, Reynolds JN, Rasmussen C, Andrew G, Hwang PA, Carlen PL. The remarkably high prevalence of epilepsy and seizure history in fetal alcohol spectrum disorders. Alcoholism, Clinical and Experimental Research. 34: 1084-9. PMID 20374205 DOI: 10.1111/J.1530-0277.2010.01184.X  0.312
2010 Shin DSH, Yu W, Fawcett A, Carlen PL. Characterizing the persistent CA3 interneuronal spiking activity in elevated extracellular potassium in the young rat hippocampus Brain Research. 1331: 39-50. PMID 20303341 DOI: 10.1016/J.Brainres.2010.03.023  0.376
2010 Ye H, Cotic M, Kang EE, Fehlings MG, Carlen PL. Transmembrane potential induced on the internal organelle by a time-varying magnetic field: a model study. Journal of Neuroengineering and Rehabilitation. 7: 12. PMID 20170538 DOI: 10.1186/1743-0003-7-12  0.765
2010 Samoilova M, Weisspapir M, Abdelmalik P, Velumian AA, Carlen PL. Chronic in vitro ketosis is neuroprotective but not anti-convulsant. Journal of Neurochemistry. 113: 826-35. PMID 20163521 DOI: 10.1111/J.1471-4159.2010.06645.X  0.387
2010 Ye H, Jalini S, Zhang L, Charlton M, Carlen PL. Early ischemia enhances action potential-dependent, spontaneous glutamatergic responses in CA1 neurons Journal of Cerebral Blood Flow and Metabolism. 30: 555-565. PMID 19844238 DOI: 10.1038/Jcbfm.2009.227  0.491
2010 Mylvaganam S, Zhang L, Wu C, Zhang ZJ, Samoilova M, Eubanks J, Carlen PL, Poulter MO. Hippocampal seizures alter the expression of the pannexin and connexin transcriptome. Journal of Neurochemistry. 112: 92-102. PMID 19840216 DOI: 10.1111/J.1471-4159.2009.06431.X  0.359
2010 Kang EE, Zalay OC, Cotic M, Carlen PL, Bardakjian BL. Transformation of neuronal modes associated with low-Mg2+/high-K+ conditions in an in vitro model of epilepsy. Journal of Biological Physics. 36: 95-107. PMID 19669427 DOI: 10.1007/S10867-009-9144-1  0.77
2009 Poochikian-Sarkissian S, Tai P, del Campo M, Andrade DM, Carlen PL, Valiante T, Wennberg RA. Patient awareness of seizures as documented in the epilepsy monitoring unit. Canadian Journal of Neuroscience Nursing. 31: 22-3. PMID 20085117  0.577
2009 Shahar E, Derchansky M, Carlen PL. The role of altered tissue osmolality on the characteristics and propagation of seizure activity in the intact isolated mouse hippocampus Clinical Neurophysiology. 120: 673-678. PMID 19299198 DOI: 10.1016/J.Clinph.2009.01.014  0.386
2009 Tonkikh AA, Carlen PL. Impaired presynaptic cytosolic and mitochondrial calcium dynamics in aged compared to young adult hippocampal CA1 synapses ameliorated by calcium chelation Neuroscience. 159: 1300-1308. PMID 19215725 DOI: 10.1016/J.Neuroscience.2008.12.057  0.306
2009 Zalay OC, Kang EE, Cotic M, Carlen PL, Bardakjian BL. A wavelet packet-based algorithm for the extraction of neural rhythms. Annals of Biomedical Engineering. 37: 595-613. PMID 19142729 DOI: 10.1007/S10439-008-9634-5  0.751
2009 Del Campo M, Abdelmalik PA, Wu CP, Carlen PL, Zhang L. Seizure-like activity in the hypoglycemic rat: lack of correlation with the electroencephalogram of free-moving animals. Epilepsy Research. 83: 243-8. PMID 19136235 DOI: 10.1016/J.Eplepsyres.2008.11.012  0.407
2009 He J, Hsiang HL, Wu C, Mylvagnanam S, Carlen PL, Zhang L. Cellular mechanisms of cobalt-induced hippocampal epileptiform discharges. Epilepsia. 50: 99-115. PMID 18727680 DOI: 10.1111/J.1528-1167.2008.01767.X  0.331
2008 Ye H, Jalini S, Mylvaganam S, Carlen P. Activation of large-conductance Ca(2+)-activated K(+) channels depresses basal synaptic transmission in the hippocampal CA1 area in APP (swe/ind) TgCRND8 mice. Neurobiology of Aging. 31: 591-604. PMID 18547679 DOI: 10.1016/J.Neurobiolaging.2008.05.012  0.485
2008 Shin DS, Carlen PL. Enhanced Ih depresses rat entopeduncular nucleus neuronal activity from high-frequency stimulation or raised Ke+ Journal of Neurophysiology. 99: 2203-2219. PMID 18305090 DOI: 10.1152/Jn.01065.2007  0.344
2008 Samoilova M, Wentlandt K, Adamchik Y, Velumian AA, Carlen PL. Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures. Experimental Neurology. 210: 762-75. PMID 18284929 DOI: 10.1016/J.Expneurol.2008.01.005  0.346
2008 Feeney CJ, Frantseva MV, Carlen PL, Pennefather PS, Shulyakova N, Shniffer C, Mills LR. Vulnerability of glial cells to hydrogen peroxide in cultured hippocampal slices. Brain Research. 1198: 1-15. PMID 18261717 DOI: 10.1016/J.Brainres.2007.12.049  0.341
2008 Derchansky M, Jahromi SS, Mamani M, Shin DS, Sik A, Carlen PL. Transition to seizures in the isolated immature mouse hippocampus: a switch from dominant phasic inhibition to dominant phasic excitation. The Journal of Physiology. 586: 477-94. PMID 17991696 DOI: 10.1113/Jphysiol.2007.143065  0.429
2008 Abdelmalik PA, Liang P, Weisspapir M, Samoilova M, Burnham WM, Carlen PL. Factors which abolish hypoglycemic seizures do not increase cerebral glycogen content in vitro. Neurobiology of Disease. 29: 201-9. PMID 17919917 DOI: 10.1016/J.Nbd.2007.08.009  0.387
2008 Ye H, Cotic M, Carlen PL. Non-conductive vs. conductive cell membranes – a reassessment of this assumption when modeling cells under magnetic field stimulation Bmc Neuroscience. 9. DOI: 10.1186/1471-2202-9-S1-P49  0.73
2007 Ye H, Cotic M, Carlen PL. Transmembrane potential induced in a spherical cell model under low-frequency magnetic stimulation. Journal of Neural Engineering. 4: 283-93. PMID 17873431 DOI: 10.1088/1741-2560/4/3/014  0.756
2007 Shin DS, Samoilova M, Cotic M, Zhang L, Brotchie JM, Carlen PL. High frequency stimulation or elevated K+ depresses neuronal activity in the rat entopeduncular nucleus. Neuroscience. 149: 68-86. PMID 17826920 DOI: 10.1016/J.Neuroscience.2007.06.055  0.738
2007 El Beheiry H, Ouanounou A, Carlen PL. L-type calcium channel blockade modifies anesthetic actions on aged hippocampal neurons Neuroscience. 147: 117-126. PMID 17507168 DOI: 10.1016/J.Neuroscience.2007.03.031  0.366
2007 Abdelmalik PA, Shannon P, Yiu A, Liang P, Adamchik Y, Weisspapir M, Samoilova M, Burnham WM, Carlen PL. Hypoglycemic seizures during transient hypoglycemia exacerbate hippocampal dysfunction. Neurobiology of Disease. 26: 646-60. PMID 17459717 DOI: 10.1016/J.Nbd.2007.03.002  0.4
2007 Andrade DM, Carlen PL. Novel antiseizure drug mechanisms Future Neurology. 2: 73-86. DOI: 10.2217/14796708.2.1.73  0.323
2007 Kang E, Carlen PL, Bardakjian B. Principal dynamic mode analysis of hippocampal neuronal networks Bmc Neuroscience. 8. DOI: 10.1186/1471-2202-8-S2-P72  0.612
2007 Ye H, Cotic M, Carlen PL. Cell-field interaction arising from tissue inhomogeneity determines electric stimulation efficiency Bmc Neuroscience. 8. DOI: 10.1186/1471-2202-8-S2-P120  0.74
2007 Derchansky M, Jahromi SS, Mamani M, Shin DS, Sik A, Carlen PL. The cellular dynamics of spontaneous transition to seizure: More exciting than you think Clinical Neurophysiology. 118: e186-e187. DOI: 10.1016/J.Clinph.2007.03.030  0.334
2006 Derchansky M, Rokni D, Rick JT, Wennberg R, Bardakjian BL, Zhang L, Yarom Y, Carlen PL. Bidirectional multisite seizure propagation in the intact isolated hippocampus: the multifocality of the seizure "focus". Neurobiology of Disease. 23: 312-28. PMID 16815026 DOI: 10.1016/J.Nbd.2006.03.014  0.415
2006 Wentlandt K, Samoilova M, Carlen PL, El Beheiry H. General anesthetics inhibit gap junction communication in cultured organotypic hippocampal slices. Anesthesia and Analgesia. 102: 1692-8. PMID 16717311 DOI: 10.1213/01.Ane.0000202472.41103.78  0.323
2006 Suffczynski P, Lopes da Silva FH, Parra J, Velis DN, Bouwman BM, van Rijn CM, van Hese P, Boon P, Khosravani H, Derchansky M, Carlen P, Kalitzin S. Dynamics of epileptic phenomena determined from statistics of ictal transitions. Ieee Transactions On Bio-Medical Engineering. 53: 524-32. PMID 16532779 DOI: 10.1109/Tbme.2005.869800  0.351
2006 Chiu AW, Jahromi SS, Khosravani H, Carlen PL, Bardakjian BL. The effects of high-frequency oscillations in hippocampal electrical activities on the classification of epileptiform events using artificial neural networks. Journal of Neural Engineering. 3: 9-20. PMID 16510938 DOI: 10.1088/1741-2560/3/1/002  0.4
2006 Chiu AW, Kang EE, Derchansky M, Carlen PL, Bardakjian BL. Online prediction of onsets of seizure-like events in hippocampal neural networks using wavelet artificial neural networks. Annals of Biomedical Engineering. 34: 282-94. PMID 16450192 DOI: 10.1007/S10439-005-9029-9  0.592
2006 Tonkikh A, Janus C, El-Beheiry H, Pennefather PS, Samoilova M, McDonald P, Ouanounou A, Carlen PL. Calcium chelation improves spatial learning and synaptic plasticity in aged rats. Experimental Neurology. 197: 291-300. PMID 16039651 DOI: 10.1016/J.Expneurol.2005.06.014  0.311
2006 Saraga F, Zhang XL, Zhang L, Carlen PL, Skinner FK. Exploring gap junction location and density in electrically coupled hippocampal oriens interneurons Neurocomputing. 69: 1048-1052. DOI: 10.1016/J.Neucom.2005.12.043  0.338
2005 L Chiu A, Derchansky M, Kang E, Carlen P, Bardakjian B. Prevention of Spontaneous Seizure-like Events in Both in-silico and in-vitro Epilepsy Models. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 3597-600. PMID 17281004 DOI: 10.1109/IEMBS.2005.1617259  0.564
2005 Chiu AW, Daniel S, Khosravani H, Carlen PL, Bardakjian BL. Prediction of seizure onset in an in-vitro hippocampal slice model of epilepsy using Gaussian-based and wavelet-based artificial neural networks. Annals of Biomedical Engineering. 33: 798-810. PMID 16078619 DOI: 10.1007/S10439-005-2346-1  0.376
2005 Khosravani H, Pinnegar CR, Mitchell JR, Bardakjian BL, Federico P, Carlen PL. Increased high-frequency oscillations precede in vitro low-Mg seizures. Epilepsia. 46: 1188-97. PMID 16060927 DOI: 10.1111/J.1528-1167.2005.65604.X  0.434
2005 Wong T, Zhang XL, Asl MN, Wu CP, Carlen PL, Zhang L. Postnatal development of intrinsic GABAergic rhythms in mouse hippocampus. Neuroscience. 134: 107-20. PMID 15961234 DOI: 10.1016/J.Neuroscience.2005.04.019  0.575
2005 Abdelmalik PA, Burnham WM, Carlen PL. Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro. Epilepsia. 46: 356-66. PMID 15730532 DOI: 10.1111/J.0013-9580.2005.34204.X  0.399
2005 Derchansky M, Shahar E, Wennberg RA, Samoilova M, Jahromi SS, Abdelmalik PA, Zhang L, Carlen PL. Model of frequent, recurrent, and spontaneous seizures in the intact mouse hippocampus. Hippocampus. 14: 935-47. PMID 15390177 DOI: 10.1002/Hipo.20007  0.432
2004 Zhang XL, Zhang L, Carlen PL. Electrotonic coupling between stratum oriens interneurones in the intact in vitro mouse juvenile hippocampus. The Journal of Physiology. 558: 825-39. PMID 15194737 DOI: 10.1113/Jphysiol.2004.065649  0.536
2003 Samoilova M, Li J, Pelletier MR, Wentlandt K, Adamchik Y, Naus CC, Carlen PL. Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression. Journal of Neurochemistry. 86: 687-99. PMID 12859682 DOI: 10.1046/J.1471-4159.2003.01893.X  0.337
2003 Fushiki S, Perez Velazquez JL, Zhang L, Bechberger JF, Carlen PL, Naus CC. Changes in neuronal migration in neocortex of connexin43 null mutant mice. Journal of Neuropathology and Experimental Neurology. 62: 304-14. PMID 12638734 DOI: 10.1093/Jnen/62.3.304  0.309
2003 Khosravani H, Carlen PL, Velazquez JL. The control of seizure-like activity in the rat hippocampal slice. Biophysical Journal. 84: 687-95. PMID 12524321 DOI: 10.1016/S0006-3495(03)74888-7  0.441
2002 Jahromi SS, Wentlandt K, Piran S, Carlen PL. Anticonvulsant actions of gap junctional blockers in an in vitro seizure model. Journal of Neurophysiology. 88: 1893-902. PMID 12364515 DOI: 10.1152/Jn.2002.88.4.1893  0.43
2002 Carlen PL, Pelletier MR, Ouanounou A, Tymianski M, Zhang L. Neuroprotective strategies in epilepsy Advances in Experimental Medicine and Biology. 497: 209-224. PMID 11993734 DOI: 10.1007/978-1-4615-1335-3_19  0.361
2002 Frantseva MV, Kokarovtseva L, Naus CG, Carlen PL, MacFabe D, Perez Velazquez JL. Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury Journal of Neuroscience. 22: 644-653. PMID 11826094 DOI: 10.1523/Jneurosci.22-03-00644.2002  0.32
2001 Li J, Shen H, Naus CCG, Zhang L, Carlen PL. Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus Neuroscience. 105: 589-598. PMID 11516826 DOI: 10.1016/S0306-4522(01)00204-4  0.305
2001 Perez Velazquez JL, Carlen PL, Skinner FK. Artificial electrotonic coupling affects neuronal firing patterns depending upon cellular characteristics. Neuroscience. 103: 841-9. PMID 11274798 DOI: 10.1016/S0306-4522(01)00019-7  0.349
2001 Valiante TA, Perez Velazquez JL, Carlen PL. Recording and analysis of putative direct electrical interactions in the mammalian brain Methods in Molecular Biology (Clifton, N.J.). 154: 395-405. PMID 11218661 DOI: 10.1385/1-59259-043-8:395  0.575
2000 Edwards HE, Epps T, Carlen PL, MacLusky NJ. Progestin receptors mediate progesterone suppression of epileptiform activity in tetanized hippocampal slices in vitro Neuroscience. 101: 895-906. PMID 11113338 DOI: 10.1016/S0306-4522(00)00439-5  0.376
2000 Jahromi SS, Pelletier MR, McDonald PJ, Khosravani H, Carlen PL. Antiepileptic efficacy of topiramate: assessment in two in vitro seizure models. Brain Research. 872: 20-8. PMID 10924671 DOI: 10.1016/S0006-8993(00)02410-0  0.422
2000 Frantseva MV, Velazquez JLP, Tsoraklidis G, Mendonca AJ, Adamchik Y, Mills LR, Carlen PL, Burnham MW. Oxidative stress is involved in seizure-induced neurodegeneration in the kindling model of epilepsy. Neuroscience. 97: 431-435. PMID 10828526 DOI: 10.1016/S0306-4522(00)00041-5  0.379
2000 Zhang XL, Velumian AA, Jones OT, Carlen PL. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate Epilepsia. 41. PMID 10768302 DOI: 10.1111/J.1528-1157.2000.Tb02173.X  0.303
2000 Frantseva MV, Velazquez JLP, Hwang PA, Carlen PL. Free radical production correlates with cell death in an in vitro model of epilepsy European Journal of Neuroscience. 12: 1431-1439. PMID 10762371 DOI: 10.1046/J.1460-9568.2000.00016.X  0.417
2000 Carlen PL, Skinner F, Zhang L, Naus C, Kushnir M, Perez Velazquez JL. The role of gap junctions in seizures Brain Research Reviews. 32: 235-241. PMID 10751673 DOI: 10.1016/S0165-0173(99)00084-3  0.393
2000 Perez Velazquez JL, Carlen PL. Gap junctions, synchrony and seizures Trends in Neurosciences. 23: 68-74. PMID 10652547 DOI: 10.1016/S0166-2236(99)01497-6  0.391
1999 Perez Velazquez JL, Carlen PL. Synchronization of GABAergic interneuronal networks during seizure-like activity in the rat horizontal hippocampal slice European Journal of Neuroscience. 11: 4110-4118. PMID 10583499 DOI: 10.1046/J.1460-9568.1999.00837.X  0.448
1999 Frantseva MV, Carlen PL, El-Beheiry H. A submersion method to induce hypoxic damage in organotypic hippocampal cultures Journal of Neuroscience Methods. 89: 25-31. PMID 10476680 DOI: 10.1016/S0165-0270(99)00030-8  0.36
1999 Velazquez JL, Khosravani H, Lozano A, Bardakjian BL, Carlen PL, Wennberg R. Type III intermittency in human partial epilepsy. The European Journal of Neuroscience. 11: 2571-6. PMID 10383646 DOI: 10.1046/J.1460-9568.1999.00688.X  0.374
1999 Pelletier MR, Wadia JS, Mills LR, Carlen PL. Seizure-induce cell death produced by repeated tetanic stimulation in vitro: Possible role of endoplasmic reticulum calcium stores Journal of Neurophysiology. 81: 3054-3064. PMID 10368420 DOI: 10.1152/Jn.1999.81.6.3054  0.369
1999 Jahromi BS, Zhang L, Carlen PL, Pennefather P. Differential time-course of slow afterhyperpolarizations and associated Ca2+ transients in rat CA1 pyramidal neurons: further dissociation by Ca2+ buffer. Neuroscience. 88: 719-26. PMID 10363812 DOI: 10.1016/S0306-4522(98)00203-6  0.329
1999 Velumian AA, Carlen PL. Differential control of three after-hyperpolarizations in rat hippocampal neurones by intracellular calcium buffering Journal of Physiology. 517: 201-216. PMID 10226160 DOI: 10.1111/J.1469-7793.1999.0201Z.X  0.347
1999 Skinner FK, Zhang L, Velazquez JL, Carlen PL. Bursting in inhibitory interneuronal networks: A role for gap-junctional coupling. Journal of Neurophysiology. 81: 1274-83. PMID 10085354 DOI: 10.1152/Jn.1999.81.3.1274  0.306
1999 Ouanounou A, Zhang L, Charlton MP, Carlen PL. Differential modulation of synaptic transmission by calcium chelators in young and aged hippocampal CA1 neurons: evidence for altered calcium homeostasis in aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 906-15. PMID 9920654 DOI: 10.1523/Jneurosci.19-03-00906.1999  0.333
1999 Skinner FK, Zhang L, Velazquez JLP, Carlen PL. Gap junctions are needed to stabilize slow bursting behaviour Neurocomputing. 26: 517-523. DOI: 10.1016/S0925-2312(99)00043-0  0.357
1998 Frantseva MV, Perez Velazquez JL, Carlen PL. Changes in membrane and synaptic properties of thalamocortical circuitry caused by hydrogen peroxide Journal of Neurophysiology. 80: 1317-1326. PMID 9744941 DOI: 10.1152/Jn.1998.80.3.1317  0.347
1998 Ouanounou A, Carlen PL, El-Beheiry H. Enhanced isoflurane suppression of excitatory synaptic transmission in the aged rat hippocampus British Journal of Pharmacology. 124: 1075-1082. PMID 9720776 DOI: 10.1038/Sj.Bjp.0701911  0.341
1998 Zhang Y, Perez Velazquez JL, Tian GF, Wu C, Skinner FK, Carlen PL, Zhang L. Slow Oscillations (≤1 Hz) Mediated by GABAergic Interneuronal Networks in Rat Hippocampus The Journal of Neuroscience. 18: 9256-9268. DOI: 10.1523/Jneurosci.18-22-09256.1998  0.398
1998 El-Beheiry H, Ouanounou A, Carlen PL. NIFEDIPINE REVERSES ANESTHETIC ACTIONS ON AGED HIPPOCAMPAL NEURONS IN IN VITRO Anesthesiology. 89: 789A. DOI: 10.1097/00000542-199809130-00095  0.334
1997 Watson PL, Weiner JL, Carlen PL. Effects of variations in hippocampal slice preparation protocol on the electrophysiological stability, epileptogenicity and graded hypoxia responses of CA1 neurons. Brain Research. 775: 134-43. PMID 9439837 DOI: 10.1016/S0006-8993(97)00893-7  0.372
1997 Vigmond EJ, Perez Velazquez JL, Valiante TA, Bardakjian BL, Carlen PL. Mechanisms of electrical coupling between pyramidal cells Journal of Neurophysiology. 78: 3107-3116. PMID 9405530 DOI: 10.1152/Jn.1997.78.6.3107  0.636
1997 Zhang Y, Carlen PL, Zhang L. Kinetics of muscarinic reduction of I(sAHP) in hippocampal neurons: Effects of acetylcholinesterase inhibitors Journal of Neurophysiology. 78: 2999-3007. PMID 9405519 DOI: 10.1152/Jn.1997.78.6.2999  0.365
1997 Perez Velazquez JL, Frantseva MV, Carlen PL. In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons Journal of Neuroscience. 17: 9085-9094. PMID 9364055 DOI: 10.1523/Jneurosci.17-23-09085.1997  0.333
1997 Shinno K, Zhang L, Eubanks JH, Carlen PL, Wallace MC. Transient ischemia induces an early decrease of synaptic transmission in CA1 neurons of rat hippocampus: Electrophysiologic study in brain slices Journal of Cerebral Blood Flow and Metabolism. 17: 955-966. PMID 9307609 DOI: 10.1097/00004647-199709000-00005  0.398
1997 Velumian AA, Zhang L, Pennefather P, Carlen PL. Reversible inhibition of IK, IAHP, Ih and ICa currents by internally applied gluconate in rat hippocampal pyramidal neurones. Pflã¼Gers Archiv : European Journal of Physiology. 433: 343-50. PMID 9064651 DOI: 10.1007/S004240050286  0.401
1997 Valiante TA, Abdul-Ghani MA, Carlen PL, Pennefather P. Analysis of current fluctuations during after-hyperpolarization current in dentate granule neurones of the rat hippocampus. The Journal of Physiology. 499: 121-34. PMID 9061644 DOI: 10.1113/Jphysiol.1997.Sp021915  0.595
1997 Eubanks JH, Perez-Velazquez JL, Kerr RG, Carlen PL, Mills LR, Jones OT. Three distinct neuronal phenotypes exist in embryonic rat hippocampal neurons cultured in basic fibroblast growth factor. Neuroscience Letters. 204: 5-8. PMID 8929964 DOI: 10.1016/0304-3940(96)12337-5  0.315
1996 Perez Velazquez JL, Frantseva M, Naus CCG, Bechberger JF, Juneja SC, Velumian A, Carlen PL, Kidder GM, Mills LR. Development of astrocytes and neurons in cultured brain slices from mice lacking connexin43 Developmental Brain Research. 97: 293-296. PMID 8997514 DOI: 10.1016/S0165-3806(96)00156-3  0.325
1996 Pelletier MR, Carlen PL. Repeated tetanic stimulation in piriform cortex in vitro: Epileptogenesis and pharmacology Journal of Neurophysiology. 76: 4069-4079. PMID 8985901 DOI: 10.1152/Jn.1996.76.6.4069  0.378
1996 Jia Z, Agopyan N, Miu P, Xiong Z, Henderson J, Gerlai R, Taverna FA, Velumian A, MacDonald J, Carlen P, Abramow-Newerly W, Roder J. Enhanced LTP in mice deficient in the AMPA receptor GluR2. Neuron. 17: 945-56. PMID 8938126 DOI: 10.1016/S0896-6273(00)80225-1  0.309
1996 Spigelman I, Tymianski M, Wallace CM, Carlen PL, Velumian AA. Modulation of hippocampal synaptic transmission by low concentrations of cell-permeant Ca2+ chelators: effects of Ca2+ affinity, chelator structure and binding kinetics. Neuroscience. 75: 559-72. PMID 8931019 DOI: 10.1016/0306-4522(96)00283-7  0.618
1996 Wright WN, Bardakjian BL, Valiante TA, Perez-Velazquez JL, Carlen PL. White noise approach for estimating the passive electrical properties of neurons. Journal of Neurophysiology. 76: 3442-50. PMID 8930284 DOI: 10.1152/Jn.1996.76.5.3442  0.595
1996 Ouanounou A, Zhang L, Tymianski M, Charlton MP, Wallace MC, Carlen PL. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 75: 99-109. PMID 8923526 DOI: 10.1016/0306-4522(96)00319-3  0.352
1996 Zhang L, Han D, Carlen PL. Temporal specificity of muscarinic synaptic modulation of the Ca 2+-dependent K + current (I(sAHP)) in rat hippocampal neurones Journal of Physiology. 496: 395-405. PMID 8910224 DOI: 10.1113/Jphysiol.1996.Sp021693  0.387
1996 Abdul-Ghani MA, Valiante TA, Carlen PL, Pennefather PS. Tyrosine kinase inhibitors enhance a Ca(2+)-activated K+ current (IAHP) and reduce IAHP suppression by a metabotropic glutamate receptor agonist in rat dentate granule neurones. The Journal of Physiology. 496: 139-44. PMID 8910202 DOI: 10.1113/Jphysiol.1996.Sp021671  0.612
1996 Abdul-Ghani MA, Valiante TA, Carlen PL, Pennefather PS. Metabotropic glutamate receptors coupled to IP3 production mediate inhibition of IAHP in rat dentate granule neurons. Journal of Neurophysiology. 76: 2691-700. PMID 8899638 DOI: 10.1152/Jn.1996.76.4.2691  0.599
1996 Perez Velazquez JL, Carlen PL. Development of firing patterns and electrical properties in neurons of the rat ventrobasal thalamus Developmental Brain Research. 91: 164-170. PMID 8852366 DOI: 10.1016/0165-3806(95)00171-9  0.381
1996 Polc P, Jahromi SS, Facciponte G, Pelletier MR, Zhang L, Carlen PL. Benzodiazepine antagonists reduce epileptiform discharges in rat hippocampal slices. Epilepsia. 37: 1007-14. PMID 8822701 DOI: 10.1111/J.1528-1157.1996.Tb00540.X  0.322
1996 El-Beheiry H, Ouanounou A, Carlen PL. Ageing potentiates anaesthetic-induced synaptic depression in hippocampal slices Neuroreport. 7: 502-504. PMID 8730815 DOI: 10.1097/00001756-199601310-00030  0.325
1995 Zhang L, Pennefather P, Velumian A, Tymianski M, Charlton M, Carlen PL. Potentiation of a slow Ca(2+)-dependent K+ current by intracellular Ca2+ chelators in hippocampal CA1 neurons of rat brain slices. Journal of Neurophysiology. 74: 2225-41. PMID 8747186 DOI: 10.1152/Jn.1995.74.6.2225  0.348
1995 Eubanks JH, Kerr RG, Perez-Velazquez JL, Carlen PL, Mills LR, Jones OT. Long-term bFGF neuronal culture: reintroduction into serum medium yields neurons and non-neuronal cells with neuronal characteristics. Neuroscience Letters. 194: 65-8. PMID 7478215 DOI: 10.1016/0304-3940(95)11728-F  0.314
1995 Valiante TA, Velazquez JLP, Jahromi SS, Carlen PL. Coupling potentials in CA1 neurons during calcium-free-induced field burst activity Journal of Neuroscience. 15: 6946-6956. PMID 7472451 DOI: 10.1523/Jneurosci.15-10-06946.1995  0.675
1994 Zhang L, Weiner JL, Valiante TA, Velumian AA, Watson PL, Jahromi SS, Schertzer S, Pennefather P, Carlen PL. Whole-cell recording of the Ca(2+)-dependent slow afterhyperpolarization in hippocampal neurones: effects of internally applied anions. Pflã¼Gers Archiv : European Journal of Physiology. 426: 247-53. PMID 8183635 DOI: 10.1007/Bf00374778  0.639
1994 Perez-Velazquez JL, Valiante TA, Carlen PL. Modulation of gap junctional mechanisms during calcium-free induced field burst activity: A possible role for electrotonic coupling in epileptogenesis Journal of Neuroscience. 14: 4308-4317. PMID 8027781 DOI: 10.1523/Jneurosci.14-07-04308.1994  0.674
1994 Perez-Velazquez JL, Valiante TA, Carlen PL. Changes in calcium currents during ethanol withdrawal in a genetic mouse model Brain Research. 649: 305-309. PMID 7953646 DOI: 10.1016/0006-8993(94)91077-4  0.571
1994 Tymianski M, Spigelman I, Zhang L, Carlen PL, Tator CH, Charlton MP, Wallace MC. Mechanism of action and persistence of neuroprotection by cell-permeant Ca2+ chelators. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 911-23. PMID 7929656 DOI: 10.1038/Jcbfm.1994.122  0.643
1994 Carlen PL, Gurevich N, Zhang L, Wu PH, Reynaud D, Pace-Asciak CR. Formation and electrophysiological actions of the arachidonic acid metabolites, hepoxilins, at nanomolar concentrations in rat hippocampal slices. Neuroscience. 58: 493-502. PMID 7909586 DOI: 10.1016/0306-4522(94)90075-2  0.313
1994 Weiner JL, Zhang L, Carlen PL. Guanosine phosphate analogs modulate ethanol potentiation of GABAA-mediated synaptic currents in hippocampal CA1 neurons. Brain Research. 665: 307-10. PMID 7895067 DOI: 10.1016/0006-8993(94)91352-8  0.33
1994 Tymianski M, Charlton MP, Carlen PL, Tator CH. Properties of neuroprotective cell-permeant Ca2+ chelators: effects on [Ca2+]i and glutamate neurotoxicity in vitro. Journal of Neurophysiology. 72: 1973-92. PMID 7823112 DOI: 10.1152/Jn.1994.72.4.1973  0.328
1994 Mills LR, Niesen CE, So AP, Carlen PL, Spigelman I, Jones OT. N-type Ca2+ channels are located on somata, dendrites, and a subpopulation of dendritic spines on live hippocampal pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6815-24. PMID 7525892 DOI: 10.1523/Jneurosci.14-11-06815.1994  0.636
1994 Velumian A, Zhang L, Carlen P, Pennefather P. 54. Further improvement of the method of internal perfusion of neurones in brain slices Journal of Neuroscience Methods. 52: A24. DOI: 10.1016/0165-0270(94)90114-7  0.31
1993 Zhang L, Valiante TA, Carlen PL. Contribution of the low-threshold T-type calcium current in generating the post-spike depolarizing afterpotential in dentate granule neurons of immature rats Journal of Neurophysiology. 70: 223-231. PMID 8395576 DOI: 10.1152/Jn.1993.70.1.223  0.623
1993 Velumian AA, Zhang L, Carlen PL. A simple method for internal perfusion of mammalian central nervous system neurones in brain slices with multiple solution changes Journal of Neuroscience Methods. 48: 131-139. PMID 8377515 DOI: 10.1016/S0165-0270(05)80015-9  0.334
1993 Jahromi SS, Schertzer S, Carlen PL. Cocaine actions on rat prefrontal cortical and hippocampal dentate granule neurons in vitro Synapse. 14: 121-127. PMID 8332944 DOI: 10.1002/Syn.890140204  0.39
1993 Tymianski M, Wallace MC, Spigelman I, Uno M, Carlen PL, Tator CH, Charlton MP. Cell-permeant Ca2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo. Neuron. 11: 221-35. PMID 8102532 DOI: 10.1016/0896-6273(93)90180-Y  0.652
1993 Tymianski M, Charlton MP, Carlen PL, Tator CH. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2085-104. PMID 8097530 DOI: 10.1523/Jneurosci.13-05-02085.1993  0.314
1993 Tymianski M, Charlton MP, Carlen PL, Tator CH. Secondary Ca2+ overload indicates early neuronal injury which precedes staining with viability indicators. Brain Research. 607: 319-23. PMID 7683241 DOI: 10.1016/0006-8993(93)91523-U  0.312
1992 Spigelman I, Zhang L, Carlen PL. Patch-clamp study of postnatal development of CA1 neurons in rat hippocampal slices: membrane excitability and K+ currents. Journal of Neurophysiology. 68: 55-69. PMID 1517828 DOI: 10.1152/Jn.1992.68.1.55  0.658
1992 Fu P, Bardakjian BL, Carlen PL. Ethanol uncouples dentate granule neurons by increasing junctional resistance: A multineuronal system model approach Neuroscience. 51: 47-54. PMID 1465185 DOI: 10.1016/0306-4522(92)90469-I  0.345
1992 Zhang L, Weiner JL, Carlen PL. Muscarinic potentiation of IK in hippocampal neurons: electrophysiological characterization of the signal transduction pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4510-20. PMID 1432107 DOI: 10.1523/Jneurosci.12-11-04510.1992  0.386
1992 Billia F, Baskys A, Carlen PL, De Boni U. Rearrangement of centromeric satellite DNA in hippocampal neurons exhibiting long-term potentiation. Brain Research. Molecular Brain Research. 14: 101-8. PMID 1323006 DOI: 10.1016/0169-328X(92)90016-5  0.324
1991 Baskys A, Carlen PL, Wojtowicz JM. Long-term potentiation of synaptic responses in the rat dentate gyrus is due to increased quantal content Neuroscience Letters. 127: 169-172. PMID 1881627 DOI: 10.1016/0304-3940(91)90786-S  0.319
1991 Zhang L, Spigelman I, Carlen PL. Development of GABA-mediated, chloride-dependent inhibition in CA1 pyramidal neurones of immature rat hippocampal slices. The Journal of Physiology. 444: 25-49. PMID 1822551 DOI: 10.1113/Jphysiol.1991.Sp018864  0.656
1991 Jahromi SS, Niesen C, Carlen PL. Amphetamine actions on pre- and postpubertal rat hippocampal dentate granule neurons Brain Research. 556: 33-43. PMID 1657305 DOI: 10.1016/0006-8993(91)90544-6  0.384
1991 Niesen C, Charlton MP, Carlen PL. Postsynaptic and presynaptic effects of the calcium chelator BAPTA on synaptic transmission in rat hippocampal dentate granule neurons. Brain Research. 555: 319-25. PMID 1657301 DOI: 10.1016/0006-8993(91)90358-3  0.35
1991 Carlen PL, Zhang L, Cullen N. Cellular electrophysiological actions of ethanol on mammalian neurons in brain slices Annals of the New York Academy of Sciences. 625: 17-25. PMID 1647722 DOI: 10.1111/J.1749-6632.1991.Tb33826.X  0.312
1990 McCrea DA, Shefchyk SJ, Carlen PL. Large reductions in composite monosynaptic EPSP amplitude following conditioning stimulation are not accounted for by increased postsynaptic conductances in motoneurons. Neuroscience Letters. 109: 117-22. PMID 2314627 DOI: 10.1016/0304-3940(90)90548-N  0.328
1990 Zhang L, Spigelman I, Carlen PL. Whole-cell patch study of GABAergic inhibition in CA1 neurons of immature rat hippocampal slices. Brain Research. Developmental Brain Research. 56: 127-30. PMID 2279324 DOI: 10.1016/0165-3806(90)90171-T  0.654
1990 Baskys A, Reynolds JN, Carlen PL. NMDA depolarizations and long-term potentiation are reduced in the aged rat neocortex Brain Research. 530: 142-146. PMID 2271944 DOI: 10.1016/0006-8993(90)90671-W  0.325
1990 Kujtan PW, Carlen PL. Phencyclidine actions measured intracellularly in hippocampal CA1 neurons Canadian Journal of Physiology and Pharmacology. 68: 1351-1356. PMID 2078827 DOI: 10.1139/Y90-204  0.345
1990 Mody I, Reynolds JN, Salter MW, Carlen PL, MacDonald JF. Kindling-induced epilepsy alters calcium currents in granule cells of rat hippocampal slices. Brain Research. 531: 88-94. PMID 1963106 DOI: 10.1016/0006-8993(90)90761-Y  0.322
1989 Fu P, Bardakjian BL, D'Aguanno A, Carlen PL. Computation of the Passive Electrical Parameters of Neurons Using a System Model Ieee Transactions On Biomedical Engineering. 36: 55-64. PMID 2921062 DOI: 10.1109/10.16449  0.303
1989 D'Aguanno A, Bardakjian BL, Carlen PL. A system model for investigating passive electrical properties of neurons Biophysical Journal. 55: 1169-1182. PMID 2765654 DOI: 10.1016/S0006-3495(89)82913-3  0.301
1989 Reynolds JN, Carlen PL. The effects of midazolam on hippocampal dentate gyrus granule neurons from young and old Fischer 344 rats Canadian Journal of Physiology and Pharmacology. 67: 359-362. PMID 2758376 DOI: 10.1139/Y89-057  0.379
1989 Blaxter TJ, Carlen PL, Niesen C. Pharmacological and anatomical separation of calcium currents in rat dentate granule neurones in vitro Journal of Physiology. 412: 93-112. PMID 2557433 DOI: 10.1113/Jphysiol.1989.Sp017605  0.331
1989 Carlen PL, Gurevich N, Wu PH, Su WG, Corey EJ, Pace-Asciak CR. Actions of arachidonic acid and hepoxilin A3 on mammalian hippocampal CA1 neurons. Brain Research. 497: 171-6. PMID 2507088 DOI: 10.1016/0006-8993(89)90984-0  0.354
1989 Reynolds JN, Carlen PL. Diminished calcium currents in aged hippocampal dentate gyrus granule neurones Brain Research. 479: 384-390. PMID 2493966 DOI: 10.1016/0006-8993(89)91646-6  0.328
1989 Baskys A, C.E. N, Davies MF, Carlen PL. Modulatory actions of serotonin on ionic conductances of hippocampal dentate granule cells Neuroscience. 29: 443-451. PMID 2471114 DOI: 10.1016/0306-4522(89)90071-7  0.379
1989 Durand D, Saint-Cyr JA, Gurevich N, Carlen PL. Ethanol-induced dendritic alterations in hippocampal granule cells Brain Research. 477: 373-377. PMID 2467727 DOI: 10.1016/0006-8993(89)91430-3  0.496
1988 Blaxter TJ, Carlen PL. Measurements of dendritic conductance changes to GABA in granule cells of the rat dentate gyrus Neuroscience. 24: 821-827. PMID 3380302 DOI: 10.1016/0306-4522(88)90070-X  0.316
1988 Niesen CE, Baskys A, Carlen PL. Reversed ethanol effects on potassium conductances in aged hippocampal dentate granule neurons Brain Research. 445: 137-141. PMID 3365551 DOI: 10.1016/0006-8993(88)91082-7  0.353
1988 Reynolds JN, Baskys A, Carlen PL. The effects of serotonin on N-methyl-d-aspartate and synaptically evoked depolarizations in rat neocortical neurons Brain Research. 456: 286-292. PMID 3061564 DOI: 10.1016/0006-8993(88)90230-2  0.301
1988 Carlen PL, Wu PH. Calcium and sedative-hypnotic drug actions International Review of Neurobiology. 29: 161-189. PMID 2456997 DOI: 10.1016/S0074-7742(08)60086-0  0.304
1987 Baskys A, Niesen CE, Carlen PL. Altered modulatory actions of serotonin on dentate granule cells of aged rats Brain Research. 419: 112-118. PMID 3676719 DOI: 10.1016/0006-8993(87)90574-9  0.343
1987 Kujtan PW, Carlen PL. Dose-dependent effects of phencyclidine on hippocampal CA1 neurons Canadian Journal of Physiology and Pharmacology. 65: 842-846. PMID 3621046 DOI: 10.1139/Y87-135  0.307
1987 O'Beirne M, Gurevich N, Carlen PL. Pentobarbital inhibits hippocampal neurons by increasing potassium conductance Canadian Journal of Physiology and Pharmacology. 65: 36-41. PMID 3567717 DOI: 10.1139/Y87-007  0.373
1987 Carlen PL, Wilkinson DA. Reversibility of alcohol-related brain damage: Clinical and experimental observations Acta Medica Scandinavica. 222: 19-26. PMID 3478966 DOI: 10.1111/J.0954-6820.1987.Tb13038.X  0.366
1987 Davies MF, Sasaki SE, Carlen PL. Benzodiazepine-induced epileptiform activity in vitro Brain Research. 437: 239-244. PMID 3435838 DOI: 10.1016/0006-8993(87)91639-8  0.311
1986 Blaxter TJ, Carlen PL, Davies MF, Kujtan PW. gamma‐Aminobutyric acid hyperpolarizes rat hippocampal pyramidal cells through a calcium‐dependent potassium conductance The Journal of Physiology. 373: 181-194. PMID 2427695 DOI: 10.1113/Jphysiol.1986.Sp016041  0.314
1985 Durand D, Carlen P. Electrotonic parameters of neurons following chronic ethanol consumption Journal of Neurophysiology. 54: 807-817. PMID 4067624 DOI: 10.1152/Jn.1985.54.4.807  0.315
1985 Blaxter TJ, Carlen PL. Pre- and postsynaptic effects of baclofen in the rat hippocampal slice Brain Research. 341: 195-199. PMID 2994814 DOI: 10.1016/0006-8993(85)91489-1  0.349
1985 Carlen PL, Gurevich N, Davies MF, Blaxter TJ, O'Beirne M. Enhanced neuronal K+ conductance: A possible common mechanism for sedative-hypnotic drug action Canadian Journal of Physiology and Pharmacology. 63: 831-837. PMID 2864130 DOI: 10.1139/Y85-137  0.341
1984 Durand D, Carlen PL. Impairment of long-term potentiation in rat hippocampus following chronic ethanol treatment Brain Research. 308: 325-332. PMID 6541071 DOI: 10.1016/0006-8993(84)91072-2  0.5
1984 McMullen PA, Saint-Cyr JA, Carlen PL. Morphological alterations in rat CA1 hippocampal pyramidal cell dendrites resulting from chronic ethanol consumption and withdrawal. The Journal of Comparative Neurology. 225: 111-8. PMID 6539344 DOI: 10.1002/Cne.902250112  0.305
1984 Durand D, Carlen PL. Decreased neuronal inhibition in vitro after long-term administration of ethanol Science. 224: 1359-1361. PMID 6328654 DOI: 10.1126/Science.6328654  0.541
1984 Puil E, Carlen PL. Attenuation of glutamate-action, excitatory postsynaptic potentials, and spikes by intracellular QX 222 in hippocampal neurons. Neuroscience. 11: 389-98. PMID 6144079 DOI: 10.1016/0306-4522(84)90031-9  0.648
1983 Carlen PL, Gurevich N, Polc P. The excitatory effects of the specific benzodiazepine antagonist Ro 14-7437, measured intracellularly in hippocampal CA1 cells Brain Research. 271: 115-119. PMID 6883110 DOI: 10.1016/0006-8993(83)91370-7  0.33
1983 Carlen PL, Gurevich N, Polc P. Low-dose benzodiazepine neuronal inhibition: enhanced Ca2+-mediated K+-conductance Brain Research. 271: 358-364. PMID 6311332 DOI: 10.1016/0006-8993(83)90302-5  0.363
1983 Kujtan PW, Carlen PL, Kapur BM. Δ9-tetrahydrocannabinol and cannabinol: Dose-dependent effects on evoked potentials in the hippocampal slice Canadian Journal of Physiology and Pharmacology. 61: 420-426. PMID 6305469 DOI: 10.1139/Y83-063  0.318
1983 Durand D, Carlen PL, Gurevich N. Electrotonnic parameters of rat dentate granule cells measured using short current pulses and HRP staining Journal of Neurophysiology. 50: 1080-1097. PMID 6196465 DOI: 10.1152/Jn.1983.50.5.1080  0.506
1982 Carlen PL, Gurevich N, Durand D. Ethanol in low doses augments calcium-mediated mechanisms measured intracellularly in hippocampal neurons Science. 215: 306-309. PMID 7053581 DOI: 10.1126/Science.7053581  0.511
1981 Durand D, Corrigall WA, Kujtan P, Carlen PL. Effects of low concentrations of ethanol on CA1 hippocampal neurons in vitro Canadian Journal of Physiology and Pharmacology. 59: 979-984. PMID 7296399 DOI: 10.1139/Y81-149  0.523
1981 Carlen PL, Durand D. Modelling the postsynaptic location and magnitude of tonic conductance changes resulting from neurotransmitters or drugs Neuroscience. 6: 839-846. PMID 6113561 DOI: 10.1016/0306-4522(81)90166-4  0.533
1976 Carlen PL, Kosower EM, Werman R. The thiol-oxidizing agent diamide increases transmitter release by decreasing calcium requirements for neuromuscular transmission in the frog. Brain Research. 117: 257-76. PMID 186154 DOI: 10.1016/0006-8993(76)90734-4  0.324
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