Olivier Civelli - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Molecular neurobiology

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vawter MP, Schulmann A, Alhassen L, Alhassen W, Hamzeh AR, Sakr J, Pauluk L, Yoshimura R, Wang X, Dai Q, Sanathara N, Civelli O, Alachkar A. Melanin Concentrating Hormone Signaling Deficits in Schizophrenia: Association with Memory and Social Impairments and Abnormal Sensorimotor Gating. The International Journal of Neuropsychopharmacology. PMID 31563948 DOI: 10.1093/ijnp/pyz051  0.8
2019 Wang L, Zhang Y, Wang C, Zhang X, Wang Z, Liang X, Alachkar A, Civelli O. A Natural Product with High Affinity to Sigma and 5-HT Receptors as Novel Therapeutic Drug for Negative and Cognitive Symptoms of Schizophrenia. Neurochemical Research. PMID 31529334 DOI: 10.1007/s11064-019-02873-7  0.8
2019 Alhassen L, Phan A, Alhassen W, Nguyen P, Lo A, Shaharuddin H, Sanathara N, Civelli O, Alachkar A. The Role of Olfaction in MCH-regulated Spontaneous Maternal Responses. Brain Research. PMID 31121161 DOI: 10.1016/j.brainres.2019.05.021  0.8
2019 Reinscheid RK, Civelli O. The History of N/OFQ and the NOP Receptor. Handbook of Experimental Pharmacology. PMID 30689090 DOI: 10.1007/164_2018_195  0.8
2018 Zhang Y, Liu Y, Wu L, Fan C, Wang Z, Zhang X, Alachkar A, Liang X, Civelli O. Receptor-specific cross talk between prostanoid 3 and bombesin subtype 3 receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700337RR. PMID 29401613 DOI: 10.1096/fj.201700337RR  0.8
2017 Sanathara NM, Garau C, Alachkar A, Wang L, Wang Z, Nishimori K, Xu X, Civelli O. Melanin concentrating hormone modulates oxytocin-mediated marble burying. Neuropharmacology. PMID 28888943 DOI: 10.1016/j.neuropharm.2017.09.008  0.8
2016 Wang L, Zhang Y, Wang Z, Gong N, Kweon TD, Vo B, Wang C, Zhang X, Chung JY, Alachkar A, Liang X, Luo DZ, Civelli O. The Antinociceptive Properties of the Corydalis yanhusuo Extract. Plos One. 11: e0162875. PMID 27622550 DOI: 10.1371/journal.pone.0162875  0.8
2016 Alachkar A, Alhassen L, Wang Z, Wang L, Onouye K, Sanathara N, Civelli O. Inactivation of the melanin concentrating hormone system impairs maternal behavior. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27617778 DOI: 10.1016/j.euroneuro.2016.08.014  0.8
2015 Zhang Y, Long Z, Guo Z, Wang Z, Zhang X, Ye RD, Liang X, Civelli O. Hydroxycinnamic acid amides from scopolia tangutica inhibit the activity of M1 muscarinic acetylcholine receptor in vitro. Fitoterapia. PMID 26586621 DOI: 10.1016/j.fitote.2015.11.007  0.64
2015 Wang L, Alachkar A, Sanathara N, Belluzzi JD, Wang Z, Civelli O. A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25991655 DOI: 10.1093/ijnp/pyv054  0.8
2014 Long Z, Zhang Y, Guo Z, Wang L, Xue X, Zhang X, Wang S, Wang Z, Civelli O, Liang X. Amide alkaloids from Scopolia tangutica. Planta Medica. 80: 1124-30. PMID 25127021 DOI: 10.1055/s-0034-1382961  0.8
2014 Zhang Y, Wang C, Guo Z, Zhang X, Wang Z, Liang X, Civelli O. Discovery of N-methyltetrahydroprotoberberines with κ-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography. Journal of Ethnopharmacology. 155: 1597-602. PMID 25107388 DOI: 10.1016/j.jep.2014.07.057  0.8
2014 Parks GS, Wang L, Wang Z, Civelli O. Identification of neuropeptide receptors expressed by melanin-concentrating hormone neurons. The Journal of Comparative Neurology. 522: 3817-33. PMID 24978951 DOI: 10.1002/cne.23642  0.64
2014 Parks GS, Olivas ND, Ikrar T, Sanathara NM, Wang L, Wang Z, Civelli O, Xu X. Histamine inhibits the melanin-concentrating hormone system: implications for sleep and arousal. The Journal of Physiology. 592: 2183-96. PMID 24639485 DOI: 10.1113/jphysiol.2013.268771  0.64
2014 Zhang Y, Wang C, Wang L, Parks GS, Zhang X, Guo Z, Ke Y, Li KW, Kim MK, Vo B, Borrelli E, Ge G, Yang L, Wang Z, Garcia-Fuster MJ, ... ... Civelli O, et al. A novel analgesic isolated from a traditional Chinese medicine. Current Biology : Cb. 24: 117-23. PMID 24388848 DOI: 10.1016/j.cub.2013.11.039  0.64
2013 Grabli D, Karachi C, Folgoas E, Monfort M, Tande D, Clark S, Civelli O, Hirsch EC, François C. Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11986-93. PMID 23864685 DOI: 10.1523/JNEUROSCI.1568-13.2013  0.64
2013 Hopf FW, Seif T, Chung S, Civelli O. MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro. Peerj. 1: e61. PMID 23646281 DOI: 10.7717/peerj.61  0.64
2013 Civelli O, Reinscheid RK, Zhang Y, Wang Z, Fredriksson R, Schiöth HB. G protein-coupled receptor deorphanizations. Annual Review of Pharmacology and Toxicology. 53: 127-46. PMID 23020293 DOI: 10.1146/annurev-pharmtox-010611-134548  0.64
2013 Zhang L, Parks GS, Wang Z, Wang L, Lew M, Civelli O. Anatomical characterization of bombesin receptor subtype-3 mRNA expression in the rodent central nervous system. The Journal of Comparative Neurology. 521: 1020-39. PMID 22911445 DOI: 10.1002/cne.23216  0.64
2012 Urbano M, Guerrero M, Zhao J, Velaparthi S, Saldanha SA, Chase P, Wang Z, Civelli O, Hodder P, Schaeffer MT, Brown S, Rosen H, Roberts E. Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7). Bioorganic & Medicinal Chemistry Letters. 22: 7135-41. PMID 23079522 DOI: 10.1016/j.bmcl.2012.09.074  0.64
2012 Chung S, Liao XH, Di Cosmo C, Van Sande J, Wang Z, Refetoff S, Civelli O. Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function. Endocrinology. 153: 6145-54. PMID 23024261 DOI: 10.1210/en.2011-1435  0.64
2012 Zhang Y, Xu J, Wang Z, Zhang X, Liang X, Civelli O. BmK-YA, an enkephalin-like peptide in scorpion venom. Plos One. 7: e40417. PMID 22792309 DOI: 10.1371/journal.pone.0040417  0.8
2012 García-Fuster MJ, Parks GS, Clinton SM, Watson SJ, Akil H, Civelli O. The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 607-13. PMID 22209364 DOI: 10.1016/j.euroneuro.2011.12.001  0.64
2012 Zhang Y, Wang Z, Cox DP, Civelli O. Study on the activation of the opioid receptors by a set of morphine derivatives in a well-defined assay system. Neurochemical Research. 37: 410-6. PMID 22002663 DOI: 10.1007/s11064-011-0627-7  0.64
2011 Chung S, Verheij MM, Hesseling P, van Vugt RW, Buell M, Belluzzi JD, Geyer MA, Martens GJ, Civelli O. The melanin-concentrating hormone (MCH) system modulates behaviors associated with psychiatric disorders. Plos One. 6: e19286. PMID 21818251 DOI: 10.1371/journal.pone.0019286  0.64
2011 Zhang Y, Wang Z, Parks GS, Civelli O. Novel neuropeptides as ligands of orphan G protein-coupled receptors. Current Pharmaceutical Design. 17: 2626-31. PMID 21728976  0.64
2011 Lee C, Parks GS, Civelli O. Anxiolytic effects of the MCH1R antagonist TPI 1361-17. Journal of Molecular Neuroscience : Mn. 43: 132-7. PMID 20635163 DOI: 10.1007/s12031-010-9425-y  0.64
2011 Chung S, Parks GS, Lee C, Civelli O. Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists. Journal of Molecular Neuroscience : Mn. 43: 115-21. PMID 20582487 DOI: 10.1007/s12031-010-9411-4  0.64
2010 Parks GS, Okumura SM, Gohil K, Civelli O. Mice lacking Melanin Concentrating Hormone 1 receptor are resistant to seizures. Neuroscience Letters. 484: 104-7. PMID 20709149 DOI: 10.1016/j.neulet.2010.08.018  0.64
2010 Chung S, Wong T, Nagasaki H, Civelli O. Acute homeostatic responses to increased fat consumption in MCH1R knockout mice. Journal of Molecular Neuroscience : Mn. 42: 459-63. PMID 20411353 DOI: 10.1007/s12031-010-9358-5  0.64
2009 Chung S, Saito Y, Civelli O. MCH receptors/gene structure-in vivo expression. Peptides. 30: 1985-9. PMID 19647772 DOI: 10.1016/j.peptides.2009.07.017  0.64
2009 Zhang L, Nothacker HP, Wang Z, Bohn LM, Civelli O. Pharmacological characterization of a selective agonist for bombesin receptor subtype-3. Biochemical and Biophysical Research Communications. 387: 283-8. PMID 19580790 DOI: 10.1016/j.bbrc.2009.07.006  0.64
2009 Chung S, Hopf FW, Nagasaki H, Li CY, Belluzzi JD, Bonci A, Civelli O. The melanin-concentrating hormone system modulates cocaine reward. Proceedings of the National Academy of Sciences of the United States of America. 106: 6772-7. PMID 19342492 DOI: 10.1073/pnas.0811331106  0.64
2009 Nagasaki H, Chung S, Dooley CT, Wang Z, Li C, Saito Y, Clark SD, Houghten RA, Civelli O. The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries. European Journal of Pharmacology. 602: 194-202. PMID 19041642 DOI: 10.1016/j.ejphar.2008.10.068  0.64
2008 Chung S, Funakoshi T, Civelli O. Orphan GPCR research. British Journal of Pharmacology. 153: S339-46. PMID 18071299 DOI: 10.1038/sj.bjp.0707606  0.64
2007 Clark SD, Alderson HL, Winn P, Latimer MP, Nothacker HP, Civelli O. Fusion of diphtheria toxin and urotensin II produces a neurotoxin selective for cholinergic neurons in the rat mesopontine tegmentum. Journal of Neurochemistry. 102: 112-20. PMID 17419804 DOI: 10.1111/j.1471-4159.2007.04529.x  0.64
2007 Dolezelova E, Nothacker HP, Civelli O, Bryant PJ, Zurovec M. A Drosophila adenosine receptor activates cAMP and calcium signaling. Insect Biochemistry and Molecular Biology. 37: 318-29. PMID 17368195 DOI: 10.1016/j.ibmb.2006.12.003  0.52
2007 Roozendaal B, Lengvilas R, McGaugh JL, Civelli O, Reinscheid RK. Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation. Learning & Memory (Cold Spring Harbor, N.Y.). 14: 29-35. PMID 17202427 DOI: 10.1101/lm.403607  0.64
2007 Xu YL, Gall CM, Jackson VR, Civelli O, Reinscheid RK. Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain. The Journal of Comparative Neurology. 500: 84-102. PMID 17099900 DOI: 10.1002/cne.21159  0.64
2006 Nagasaki H, Wang Z, Jackson VR, Lin S, Nothacker HP, Civelli O. Differential expression of the thyrostimulin subunits, glycoprotein alpha2 and beta5 in the rat pituitary. Journal of Molecular Endocrinology. 37: 39-50. PMID 16901922 DOI: 10.1677/jme.1.01932  0.64
2006 Chung S, Civelli O. Orphan neuropeptides. Novel neuropeptides modulating sleep or feeding. Neuropeptides. 40: 233-43. PMID 16814380 DOI: 10.1016/j.npep.2006.04.002  0.64
2006 Jackson VR, Lin SH, Wang Z, Nothacker HP, Civelli O. A study of the rat neuropeptide B/neuropeptide W system using in situ techniques. The Journal of Comparative Neurology. 497: 367-83. PMID 16736466 DOI: 10.1002/cne.20989  0.64
2006 Jackson VR, Nothacker HP, Civelli O. GPR39 receptor expression in the mouse brain. Neuroreport. 17: 813-6. PMID 16708020 DOI: 10.1097/01.wnr.0000215779.76602.93  0.52
2006 Wang Z, Takahashi T, Saito Y, Nagasaki H, Ly NK, Nothacker HP, Reinscheid RK, Yang J, Chang JK, Shichiri M, Civelli O. Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1. European Journal of Pharmacology. 539: 145-50. PMID 16697365 DOI: 10.1016/j.ejphar.2006.03.064  0.64
2006 Chung S, Pohl S, Zeng J, Civelli O, Reinscheid RK. Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance. The Journal of Pharmacology and Experimental Therapeutics. 318: 262-7. PMID 16595734 DOI: 10.1124/jpet.106.103960  0.64
2006 Okuda-Ashitaka E, Minami T, Matsumura S, Takeshima H, Reinscheid RK, Civelli O, Ito S. The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2-induced allodynia, tactile pain associated with nerve injury. The European Journal of Neuroscience. 23: 995-1004. PMID 16519664 DOI: 10.1111/j.1460-9568.2006.04623.x  0.64
2006 Civelli O, Saito Y, Wang Z, Nothacker HP, Reinscheid RK. Orphan GPCRs and their ligands. Pharmacology & Therapeutics. 110: 525-32. PMID 16289308 DOI: 10.1016/j.pharmthera.2005.10.001  0.64
2005 Arai AC, Xia YF, Suzuki E, Kessler M, Civelli O, Nothacker HP. Cancer metastasis-suppressing peptide metastin upregulates excitatory synaptic transmission in hippocampal dentate granule cells. Journal of Neurophysiology. 94: 3648-52. PMID 16222076 DOI: 10.1152/jn.00590.2005  0.64
2005 Clark SD, Nothacker HP, Blaha CD, Tyler CJ, Duangdao DM, Grupke SL, Helton DR, Leonard CS, Civelli O. Urotensin II acts as a modulator of mesopontine cholinergic neurons. Brain Research. 1059: 139-48. PMID 16183039 DOI: 10.1016/j.brainres.2005.08.026  0.64
2005 Reinscheid RK, Xu YL, Okamura N, Zeng J, Chung S, Pai R, Wang Z, Civelli O. Pharmacological characterization of human and murine neuropeptide s receptor variants. The Journal of Pharmacology and Experimental Therapeutics. 315: 1338-45. PMID 16144971 DOI: 10.1124/jpet.105.093427  0.64
2005 Nothacker HP, Wang Z, Zeng H, Mahata SK, O'Connor DT, Civelli O. Proadrenomedullin N-terminal peptide and cortistatin activation of MrgX2 receptor is based on a common structural motif. European Journal of Pharmacology. 519: 191-3. PMID 16111673 DOI: 10.1016/j.ejphar.2005.07.001  0.8
2005 Huitron-Resendiz S, Kristensen MP, Sánchez-Alavez M, Clark SD, Grupke SL, Tyler C, Suzuki C, Nothacker HP, Civelli O, Criado JR, Henriksen SJ, Leonard CS, de Lecea L. Urotensin II modulates rapid eye movement sleep through activation of brainstem cholinergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5465-74. PMID 15944374 DOI: 10.1523/JNEUROSCI.4501-04.2005  0.64
2005 Reinscheid RK, Xu YL, Civelli O. Neuropeptide S: a new player in the modulation of arousal and anxiety. Molecular Interventions. 5: 42-6. PMID 15731503 DOI: 10.1124/mi5.1.8  0.64
2004 Xu YL, Jackson VR, Civelli O. Orphan G protein-coupled receptors and obesity. European Journal of Pharmacology. 500: 243-53. PMID 15464037 DOI: 10.1016/j.ejphar.2004.07.029  0.64
2004 Xu YL, Reinscheid RK, Huitron-Resendiz S, Clark SD, Wang Z, Lin SH, Brucher FA, Zeng J, Ly NK, Henriksen SJ, de Lecea L, Civelli O. Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. Neuron. 43: 487-97. PMID 15312648 DOI: 10.1016/j.neuron.2004.08.005  0.64
2003 Reinscheid RK, Kim J, Zeng J, Civelli O. High-throughput real-time monitoring of Gs-coupled receptor activation in intact cells using cyclic nucleotide-gated channels. European Journal of Pharmacology. 478: 27-34. PMID 14555181 DOI: 10.1016/j.ejphar.2003.08.036  0.64
2002 Lin SH, Leslie FM, Civelli O. Neurochemical properties of the prolactin releasing peptide (PrRP) receptor expressing neurons: evidence for a role of PrRP as a regulator of stress and nociception. Brain Research. 952: 15-30. PMID 12363400 DOI: 10.1016/S0006-8993(02)03183-9  0.64
2002 Reinscheid RK, Civelli O. The orphanin FQ/nociceptin knockout mouse: a behavioral model for stress responses. Neuropeptides. 36: 72-6. PMID 12359498 DOI: 10.1054/npep.2002.0901  0.64
2002 Lin SH, Arai AC, España RA, Berridge CW, Leslie FM, Huguenard JR, Vergnes M, Civelli O. Prolactin-releasing peptide (PrRP) promotes awakening and suppresses absence seizures. Neuroscience. 114: 229-38. PMID 12207968 DOI: 10.1016/S0306-4522(02)00248-8  0.64
2001 Clark SD, Nothacker HP, Wang Z, Saito Y, Leslie FM, Civelli O. The urotensin II receptor is expressed in the cholinergic mesopontine tegmentum of the rat. Brain Research. 923: 120-7. PMID 11743979 DOI: 10.1016/S0006-8993(01)03208-5  0.64
2001 Saito Y, Wang Z, Hagino-Yamagishi K, Civelli O, Kawashima S, Maruyama K. Endogenous melanin-concentrating hormone receptor SLC-1 in human melanoma SK-MEL-37 cells. Biochemical and Biophysical Research Communications. 289: 44-50. PMID 11708774 DOI: 10.1006/bbrc.2001.5926  0.8
2001 Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. Molecular Pharmacology. 60: 916-23. PMID 11641419  0.64
2001 Saito Y, Cheng M, Leslie FM, Civelli O. Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain. The Journal of Comparative Neurology. 435: 26-40. PMID 11370009 DOI: 10.1002/cne.1191  0.64
2001 Civelli O, Nothacker HP, Saito Y, Wang Z, Lin SH, Reinscheid RK. Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors. Trends in Neurosciences. 24: 230-7. PMID 11250008 DOI: 10.1016/S0166-2236(00)01763-X  0.64
2000 Nothacker HP, Wang Z, Zhu Y, Reinscheid RK, Lin SH, Civelli O. Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. Molecular Pharmacology. 58: 1601-8. PMID 11093801  0.64
2000 Reinscheid RK, Nothacker H, Civelli O. The orphanin FQ/nociceptin gene: structure, tissue distribution of expression and functional implications obtained from knockout mice. Peptides. 21: 901-6. PMID 10998523 DOI: 10.1016/S0196-9781(00)00226-6  0.64
2000 Saito Y, Nothacker HP, Civelli O. Melanin-concentrating hormone receptor: an orphan receptor fits the key. Trends in Endocrinology and Metabolism: Tem. 11: 299-303. PMID 10996523 DOI: 10.1016/S1043-2760(00)00290-3  0.52
1999 Civelli O, Nothacker HP. Functional genomics and the discovery of new drug targets. Diabetes Technology & Therapeutics. 1: 71-6. PMID 11475307  0.52
1999 Civelli O, Reinscheid RK, Nothacker HP. Orphan receptors, novel neuropeptides and reverse pharmaceutical research. Brain Research. 848: 63-5. PMID 10612697 DOI: 10.1016/S0006-8993(99)02041-7  0.64
1999 Nothacker HP, Wang Z, McNeill AM, Saito Y, Merten S, O'Dowd B, Duckles SP, Civelli O. Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nature Cell Biology. 1: 383-5. PMID 10559967 DOI: 10.1038/14081  0.64
1999 Köster A, Montkowski A, Schulz S, Stübe EM, Knaudt K, Jenck F, Moreau JL, Nothacker HP, Civelli O, Reinscheid RK. Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 10444-9. PMID 10468628 DOI: 10.1073/pnas.96.18.10444  0.64
1999 Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, Akil H, Watson SJ. Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: comparison of ORL1 receptor mRNA expression with (125)I-[(14)Tyr]-orphanin FQ binding. The Journal of Comparative Neurology. 412: 563-605. PMID 10464356 DOI: 10.1002/(SICI)1096-9861(19991004)412:4<563::AID-CNE2>3.0.CO;2-Z  0.64
1999 Reinscheid RK, Nothacker HP, Civelli O. Orphan receptors and the concept of reverse physiology: discovery of the novel neuropeptide orphanin FQ/nociceptin. Results and Problems in Cell Differentiation. 26: 193-214. PMID 10453465  0.64
1999 Saito Y, Nothacker HP, Wang Z, Lin SH, Leslie F, Civelli O. Molecular characterization of the melanin-concentrating-hormone receptor. Nature. 400: 265-9. PMID 10421368 DOI: 10.1038/22321  0.64
1999 Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, Watson SJ. Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat. The Journal of Comparative Neurology. 406: 503-47. PMID 10205026 DOI: 10.1002/(SICI)1096-9861(19990419)406:4<503::AID-CNE7>3.0.CO;2-P  0.64
1998 Civelli O, Nothacker HP, Reinscheid R. Reverse physiology: discovery of the novel neuropeptide, orphanin FQ/nociceptin. Critical Reviews in Neurobiology. 12: 163-76. PMID 9847053  0.64
1998 Meng F, Ueda Y, Hoversten MT, Taylor LP, Reinscheid RK, Monsma FJ, Watson SJ, Civelli O, Akil H. Creating a functional opioid alkaloid binding site in the orphanin FQ receptor through site-directed mutagenesis. Molecular Pharmacology. 53: 772-7. PMID 9547370  0.64
1998 Zenner MT, Nobile M, Henningsen R, Smeraldi E, Civelli O, Hartman DS, Catalano M. Expression and characterization of a dopamine D4R variant associated with delusional disorder. Febs Letters. 422: 146-50. PMID 9489994 DOI: 10.1016/S0014-5793(97)01617-7  0.64
1998 Ferré S, Torvinen M, Antoniou K, Irenius E, Civelli O, Arenas E, Fredholm BB, Fuxe K. Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. The Journal of Biological Chemistry. 273: 4718-24. PMID 9468534 DOI: 10.1074/jbc.273.8.4718  0.64
1998 Reinscheid RK, Higelin J, Henningsen RA, Monsma FJ, Civelli O. Structures that delineate orphanin FQ and dynorphin A pharmacological selectivities. The Journal of Biological Chemistry. 273: 1490-5. PMID 9430687 DOI: 10.1074/jbc.273.3.1490  0.64
1997 Jenck F, Moreau JL, Martin JR, Kilpatrick GJ, Reinscheid RK, Monsma FJ, Nothacker HP, Civelli O. Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress. Proceedings of the National Academy of Sciences of the United States of America. 94: 14854-8. PMID 9405703 DOI: 10.1073/pnas.94.26.14854  0.64
1997 Ardati A, Henningsen RA, Higelin J, Reinscheid RK, Civelli O, Monsma FJ. Interaction of [3H]orphanin FQ and 125I-Tyr14-orphanin FQ with the orphanin FQ receptor: kinetics and modulation by cations and guanine nucleotides. Molecular Pharmacology. 51: 816-24. PMID 9145920  0.64
1997 Civelli O, Nothacker HP, Bourson A, Ardati A, Monsma F, Reinscheid R. Orphan receptors and their natural ligands. Journal of Receptor and Signal Transduction Research. 17: 545-50. PMID 9029514 DOI: 10.3109/10799899709036627  0.64
1997 Lanau F, Zenner MT, Civelli O, Hartman DS. Epinephrine and norepinephrine act as potent agonists at the recombinant human dopamine D4 receptor. Journal of Neurochemistry. 68: 804-12. PMID 9003072  0.64
1996 Devine DP, Taylor L, Reinscheid RK, Monsma FJ, Civelli O, Akil H. Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ. Neurochemical Research. 21: 1387-96. PMID 8947929 DOI: 10.1007/BF02532380  0.64
1996 Meng F, Taylor LP, Hoversten MT, Ueda Y, Ardati A, Reinscheid RK, Monsma FJ, Watson SJ, Civelli O, Akil H. Moving from the orphanin FQ receptor to an opioid receptor using four point mutations. The Journal of Biological Chemistry. 271: 32016-20. PMID 8943250 DOI: 10.1074/jbc.271.50.32016  0.64
1996 Mogil JS, Grisel JE, Reinscheid RK, Civelli O, Belknap JK, Grandy DK. Orphanin FQ is a functional anti-opioid peptide. Neuroscience. 75: 333-7. PMID 8930999 DOI: 10.1016/0306-4522(96)00338-7  0.64
1996 Devine DP, Reinscheid RK, Monsma FJ, Civelli O, Akil H. The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion. Brain Research. 727: 225-9. PMID 8842403 DOI: 10.1016/0006-8993(96)00476-3  0.64
1996 Knoflach F, Reinscheid RK, Civelli O, Kemp JA. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6657-64. PMID 8824306  0.64
1996 Nothacker HP, Reinscheid RK, Mansour A, Henningsen RA, Ardati A, Monsma FJ, Watson SJ, Civelli O. Primary structure and tissue distribution of the orphanin FQ precursor. Proceedings of the National Academy of Sciences of the United States of America. 93: 8677-82. PMID 8710930 DOI: 10.1073/pnas.93.16.8677  0.64
1996 Reinscheid RK, Ardati A, Monsma FJ, Civelli O. Structure-activity relationship studies on the novel neuropeptide orphanin FQ. The Journal of Biological Chemistry. 271: 14163-8. PMID 8662940 DOI: 10.1074/jbc.271.24.14163  0.64
1995 Watts VJ, Lawler CP, Gonzales AJ, Zhou QY, Civelli O, Nichols DE, Mailman RB. Spare receptors and intrinsic activity: studies with D1 dopamine receptor agonists. Synapse (New York, N.Y.). 21: 177-87. PMID 8584979 DOI: 10.1002/syn.890210211  0.64
1995 Bouvier C, Bunzow JR, Guan HC, Unteutsch A, Civelli O, Grandy DK, Van Tol HH. Functional characterization of the human dopamine D4.2 receptor using vaccinia virus as an expression system. European Journal of Pharmacology. 290: 11-7. PMID 7664820 DOI: 10.1016/0922-4106(95)90011-X  0.64
1995 Reinscheid RK, Nothacker HP, Bourson A, Ardati A, Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma FJ, Civelli O. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science (New York, N.Y.). 270: 792-4. PMID 7481766  0.64
1994 Porter TE, Grandy D, Bunzow J, Wiles CD, Civelli O, Frawley LS. Evidence that stimulatory dopamine receptors may be involved in the regulation of prolactin secretion. Endocrinology. 134: 1263-8. PMID 8119166 DOI: 10.1210/endo.134.3.8119166  0.64
1994 Hershberger RE, Newman BL, Florio T, Bunzow J, Civelli O, Li XJ, Forte M, Stork PJ. The somatostatin receptors SSTR1 and SSTR2 are coupled to inhibition of adenylyl cyclase in Chinese hamster ovary cells via pertussis toxin-sensitive pathways. Endocrinology. 134: 1277-85. PMID 7907016 DOI: 10.1210/endo.134.3.7907016  0.64
1993 Civelli O, Bunzow JR, Grandy DK. Molecular diversity of the dopamine receptors. Annual Review of Pharmacology and Toxicology. 33: 281-307. PMID 8494342 DOI: 10.1146/annurev.pa.33.040193.001433  0.64
1993 Bouvier C, Salon JA, Johnson RA, Civelli O. Dopaminergic activity measured in D1- and D2-transfected fibroblasts by silicon-microphysiometry. Journal of Receptor Research. 13: 559-71. PMID 8450504 DOI: 10.3109/10799899309073679  0.64
1993 Gelernter J, Kennedy JL, Grandy DK, Zhou QY, Civelli O, Pauls DL, Pakstis A, Kurlan R, Sunahara RK, Niznik HB. Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor. The American Journal of Psychiatry. 150: 449-53. PMID 8434661  0.64
1993 Fox CA, Mansour A, Thompson RC, Bunzow JR, Civelli O, Watson SJ. The distribution of dopamine D2 receptor heteronuclear RNA (hnRNA) in the rat brain. Journal of Chemical Neuroanatomy. 6: 363-73. PMID 8142073 DOI: 10.1016/0891-0618(93)90011-R  0.64
1993 Grandy DK, Zhang Y, Civelli O. PCR detection of the TaqA RFLP at the DRD2 locus. Human Molecular Genetics. 2: 2197. PMID 7906592  0.48
1992 Grandy DK, Civelli O. G-protein-coupled receptors: the new dopamine receptor subtypes. Current Opinion in Neurobiology. 2: 275-81. PMID 1643409 DOI: 10.1016/0959-4388(92)90115-2  0.64
1992 Mansour A, Meador-Woodruff JH, Zhou Q, Civelli O, Akil H, Watson SJ. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience. 46: 959-71. PMID 1531866 DOI: 10.1016/0306-4522(92)90197-A  0.64
1992 Civelli O, Bunzow JR, Zhou QY, Grandy DK. The diversity of the dopamine receptors. Nida Research Monograph. 126: 23-33. PMID 1491715  0.64
1992 Eubanks JH, Djabali M, Selleri L, Grandy DK, Civelli O, McElligott DL, Evans GA. Structure and linkage of the D2 dopamine receptor and neural cell adhesion molecule genes on human chromosome 11q23. Genomics. 14: 1010-8. PMID 1478642 DOI: 10.1016/S0888-7543(05)80124-7  0.64
1992 Meador-Woodruff JH, Mansour A, Grandy DK, Damask SP, Civelli O, Watson SJ. Distribution of D5 dopamine receptor mRNA in rat brain. Neuroscience Letters. 145: 209-12. PMID 1465219 DOI: 10.1016/0304-3940(92)90024-2  0.64
1992 Grandy DK, Allen LJ, Zhang Y, Magenis RE, Civelli O. Chromosomal localization of three human D5 dopamine receptor genes. Genomics. 13: 968-73. PMID 1387108 DOI: 10.1016/0888-7543(92)90009-H  0.64
1992 Vallar L, Muca C, Civelli O, Meldolesi J. The D2 receptor: an inhibitory receptor which can trigger stimulatory responses. Neurochemistry International. 20: 197S-200S. PMID 1365425 DOI: 10.1016/0197-0186(92)90238-M  0.64
1992 Jensen S, Plaetke R, Holik J, Hoff M, O'Connell P, Reimherr F, Wender P, Zhou QY, Civelli O, Litt M. Linkage analysis of the D1 dopamine receptor gene and manic depression in six families. Human Heredity. 42: 269-75. PMID 1360940  0.32
1992 Florio T, Pan MG, Newman B, Hershberger RE, Civelli O, Stork PJ. Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity. The Journal of Biological Chemistry. 267: 24169-72. PMID 1360008  0.64
1992 Mansour A, Meng F, Meador-Woodruff JH, Taylor LP, Civelli O, Akil H. Site-directed mutagenesis of the human dopamine D2 receptor. European Journal of Pharmacology. 227: 205-14. PMID 1358663 DOI: 10.1016/0922-4106(92)90129-J  0.64
1992 Seeman P, Guan HC, Civelli O, Van Tol HH, Sunahara RK, Niznik HB. The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography. European Journal of Pharmacology. 227: 139-46. PMID 1358662 DOI: 10.1016/0922-4106(92)90121-B  0.64
1992 Grandy DK, Leduc R, Makam H, Flanagan T, Diliberto EJ, Civelli O, Viveros OH. Nucleotide and deduced amino acid sequence of bovine adrenal medulla chromogranin B (secretogranin I). Cellular and Molecular Neurobiology. 12: 185-92. PMID 1350945 DOI: 10.1007/BF00713372  0.64
1992 Gelernter J, Pakstis AJ, Grandy D, Litt M, Retief AE, Kennedy JL, Hing-Loh A, Schoolfield G, Civelli O, Kidd KK. Linkage map of eight human chromosome 11q markers, including DRD2, spanning 60 cM. Cytogenetics and Cell Genetics. 60: 26-8. PMID 1349858  0.32
1992 Liu YF, Civelli O, Grandy DK, Albert PR. Differential sensitivity of the short and long human dopamine D2 receptor subtypes to protein kinase C. Journal of Neurochemistry. 59: 2311-7. PMID 1331329  0.64
1992 Van Tol HH, Wu CM, Guan HC, Ohara K, Bunzow JR, Civelli O, Kennedy J, Seeman P, Niznik HB, Jovanovic V. Multiple dopamine D4 receptor variants in the human population. Nature. 358: 149-52. PMID 1319557 DOI: 10.1038/358149a0  0.64
1991 Moises HW, Gelernter J, Giuffra LA, Zarcone V, Wetterberg L, Civelli O, Kidd KK, Cavalli-Sforza LL, Grandy DK, Kennedy JL. No linkage between D2 dopamine receptor gene region and schizophrenia. Archives of General Psychiatry. 48: 643-7. PMID 2069495 DOI: 10.1001/archpsyc.1991.01810310061011  0.64
1991 Bates MD, Senogles SE, Bunzow JR, Liggett SB, Civelli O, Caron MG. Regulation of responsiveness at D2 dopamine receptors by receptor desensitization and adenylyl cyclase sensitization. Molecular Pharmacology. 39: 55-63. PMID 1846220  0.64
1991 Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature. 350: 610-4. PMID 1840645 DOI: 10.1038/350610a0  0.64
1991 Meador-Woodruff JH, Mansour A, Healy DJ, Kuehn R, Zhou QY, Bunzow JR, Akil H, Civelli O, Watson SJ. Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 5: 231-42. PMID 1839499  0.64
1991 Civelli O, Bunzow J, Albert P, Van Tol H, Grandy D. Molecular biology of the dopamine D2 receptor. Nida Research Monograph. 111: 45-53. PMID 1837843  0.32
1991 Sarkar G, Kapelner S, Grandy DK, Marchionni M, Civelli O, Sobell J, Heston L, Sommer SS. Direct sequencing of the dopamine D2 receptor (DRD2) in schizophrenics reveals three polymorphisms but no structural change in the receptor. Genomics. 11: 8-14. PMID 1837284 DOI: 10.1016/0888-7543(91)90096-W  0.64
1991 Meador-Woodruff JH, Mansour A, Civelli O, Watson SJ. Distribution of D2 dopamine receptor mRNA in the primate brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 15: 885-93. PMID 1837159 DOI: 10.1016/0278-5846(91)90016-T  0.64
1991 Grandy DK, Zhang YA, Bouvier C, Zhou QY, Johnson RA, Allen L, Buck K, Bunzow JR, Salon J, Civelli O. Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes. Proceedings of the National Academy of Sciences of the United States of America. 88: 9175-9. PMID 1833775  0.64
1991 Civelli O, Bunzow JR, Grandy DK, Zhou QY, Van Tol HH. Molecular biology of the dopamine receptors. European Journal of Pharmacology. 207: 277-86. PMID 1783000 DOI: 10.1016/0922-4106(91)90001-X  0.64
1991 Mansour A, Meador-Woodruff JH, Zhou QY, Civelli O, Akil H, Watson SJ. A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience. 45: 359-71. PMID 1762683 DOI: 10.1016/0306-4522(91)90233-E  0.64
1991 Hauge XY, Grandy DK, Eubanks JH, Evans GA, Civelli O, Litt M. Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene. Genomics. 10: 527-30. PMID 1679742 DOI: 10.1016/0888-7543(91)90431-D  0.64
1991 Litt M, al-Dhalimy M, Zhou Q, Grandy D, Civelli O. A TaqI RFLP at the DRD1 locus. Nucleic Acids Research. 19: 3161. PMID 1676155  0.32
1990 Devor EJ, Grandy DK, Civelli O, Litt M, Burgess AK, Isenberg KE, van de Wetering BJ, Oostra B. Genetic linkage is excluded for the D2-dopamine receptor lambda HD2G1 and flanking loci on chromosome 11q22-q23 in Tourette syndrome. Human Heredity. 40: 105-8. PMID 2335364 DOI: 10.1159/000153914  0.64
1990 Zhou QY, Grandy DK, Thambi L, Kushner JA, Van Tol HH, Cone R, Pribnow D, Salon J, Bunzow JR, Civelli O. Cloning and expression of human and rat D1 dopamine receptors. Nature. 347: 76-80. PMID 2168520 DOI: 10.1038/347076a0  0.64
1990 Vallar L, Muca C, Magni M, Albert P, Bunzow J, Meldolesi J, Civelli O. Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells. The Journal of Biological Chemistry. 265: 10320-6. PMID 2162345  0.64
1990 Mansour A, Meador-Woodruff JH, Bunzow JR, Civelli O, Akil H, Watson SJ. Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2587-600. PMID 2143777  0.64
1990 Bates MD, Gingrich JA, Bunzow JR, Falardeau P, Dearry A, Senogles SE, Civelli O, Caron MG. Molecular characterization of dopamine receptors. American Journal of Hypertension. 3: 29S-33S. PMID 2143386  0.64
1990 Mansour A, Meador-Woodruff JH, Camp DM, Robinson TE, Bunzow J, Van Tol H, Civelli O, Akil H, Watson SJ. The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems. Progress in Clinical and Biological Research. 328: 227-30. PMID 2106148  0.64
1990 Gelernter J, Pakstis AJ, Pauls DL, Kurlan R, Gancher ST, Civelli O, Grandy D, Kidd KK. Gilles de la Tourette syndrome is not linked to D2-dopamine receptor. Archives of General Psychiatry. 47: 1073-7. PMID 1978653  0.32
1990 Grandy DK, Hanneman E, Bunzow J, Shih M, Machida CA, Bidlack JM, Civelli O. Purification, cloning, and tissue distribution of a 23-kDa rat protein isolated by morphine affinity chromatography. Molecular Endocrinology (Baltimore, Md.). 4: 1370-6. PMID 1978248 DOI: 10.1210/mend-4-9-1370  0.64
1990 Grandy DK, Zhou QY, Allen L, Litt R, Magenis RE, Civelli O, Litt M. A human D1 dopamine receptor gene is located on chromosome 5 at q35.1 and identifies an EcoRI RFLP. American Journal of Human Genetics. 47: 828-34. PMID 1977312  0.64
1990 van Tol HH, Riva M, Civelli O, Creese I. Lack of effect of chronic dopamine receptor blockade on D2 dopamine receptor mRNA level. Neuroscience Letters. 111: 303-8. PMID 1970862 DOI: 10.1016/0304-3940(90)90279-I  0.64
1989 Grandy DK, Litt M, Allen L, Bunzow JR, Marchionni M, Makam H, Reed L, Magenis RE, Civelli O. The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP. American Journal of Human Genetics. 45: 778-85. PMID 2573278  0.64
1989 Machida CA, Bunzow J, Hanneman E, Grandy D, Civelli O. Replica filter screening technique to detect transfected cells expressing beta 2-adrenergic receptor. Dna (Mary Ann Liebert, Inc.). 8: 447-55. PMID 2550194  0.32
1989 Meador-Woodruff JH, Mansour A, Bunzow JR, Van Tol HH, Watson SJ, Civelli O. Distribution of D2 dopamine receptor mRNA in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 86: 7625-8. PMID 2529545  0.64
1988 Bunzow JR, Van Tol HH, Grandy DK, Albert P, Salon J, Christie M, Machida CA, Neve KA, Civelli O. Cloning and expression of a rat D2 dopamine receptor cDNA. Nature. 336: 783-7. PMID 2974511 DOI: 10.1038/336783a0  0.64
1988 Iadarola MJ, Douglass J, Civelli O, Naranjo JR. Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization. Brain Research. 455: 205-12. PMID 2900057 DOI: 10.1016/0006-8993(88)90078-9  0.64
1988 Sivam SP, Takeuchi K, Li S, Douglass J, Civelli O, Calvetta L, Herbert E, McGinty JF, Hong JS. Lithium increases dynorphin A(1-8) and prodynorphin mRNA levels in the basal ganglia of rats. Brain Research. 427: 155-63. PMID 2898269 DOI: 10.1016/0169-328X(88)90061-7  0.64
1988 Machida CA, Salon J, Grandy D, Bunzow J, Albert P, Hanneman E, Civelli O. Three technical approaches for cloning opioid receptors. Nida Research Monograph. 87: 93-110. PMID 2855100  0.64
1987 Douglass J, Cox B, Quinn B, Civelli O, Herbert E. Expression of the prodynorphin gene in male and female mammalian reproductive tissues. Endocrinology. 120: 707-13. PMID 2879723 DOI: 10.1210/endo-120-2-707  0.64
1987 Civelli O, Machida C, Bunzow J, Albert P, Hanneman E, Salon J, Bidlack J, Grandy D. The next frontier in the molecular biology of the opioid system. The opioid receptors. Molecular Neurobiology. 1: 373-91. PMID 2855792 DOI: 10.1007/BF02935742  0.64
1986 Civelli O, Douglass J, Rosen H, Martens G, Herbert E. Biosynthesis of opioid peptides. Nida Research Monograph. 70: 21-42. PMID 3093878  0.64
1986 Khachaturian H, Sherman TG, Lloyd RV, Civelli O, Douglass J, Herbert E, Akil H, Watson SJ. Pro-dynorphin is endogenous to the anterior pituitary and is co-localized with LH and FSH in the gonadotrophs. Endocrinology. 119: 1409-11. PMID 3089769 DOI: 10.1210/endo-119-3-1409  0.64
1986 Iadarola MJ, Douglass J, Civelli O, Naranjo JR. Increased spinal cord dynorphin mRNA during peripheral inflammation. Nida Research Monograph. 75: 406-9. PMID 2893274  0.64
1985 Civelli O, Douglass J, Goldstein A, Herbert E. Sequence and expression of the rat prodynorphin gene. Proceedings of the National Academy of Sciences of the United States of America. 82: 4291-5. PMID 3858883  0.64
1984 Douglass J, Civelli O, Herbert E. Polyprotein gene expression: generation of diversity of neuroendocrine peptides. Annual Review of Biochemistry. 53: 665-715. PMID 6383203 DOI: 10.1146/annurev.bi.53.070184.003313  0.64
1984 Douglass JO, Civelli O, Birnberg N, Comb M, Uhler M, Lissitzky JC, Herbert E. Regulation of expression of opioid peptide genes. Annals of Neurology. 16: S22-30. PMID 6095739 DOI: 10.1002/ana.410160706  0.64
1983 Civelli O, Birnberg N, Comb M, Douglass J, Lissitzky JC, Uhler M, Herbert E. Regulation of opioid gene expression. Peptides. 4: 651-6. PMID 6318201 DOI: 10.1016/0196-9781(83)90013-X  0.64
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