Moses Rodriguez, MD - Publications

Affiliations: 
Neurology Mayo Clinic, Rochester, MN, United States 

277 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chitnis T, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, ... ... Rodriguez M, et al. Improved relapse recovery in paediatric compared to adult multiple sclerosis. Brain : a Journal of Neurology. PMID 32810215 DOI: 10.1093/Brain/Awaa199  0.32
2020 Hayden L, Semenoff T, Schultz V, Merz SF, Chapple KJ, Rodriguez M, Warrington AE, Shi X, McKimmie CS, Edgar JM, Thümmler K, Linington C, Pingen M. Lipid-specific IgMs induce antiviral responses in the CNS: implications for progressive multifocal leukoencephalopathy in multiple sclerosis. Acta Neuropathologica Communications. 8: 135. PMID 32792006 DOI: 10.1186/S40478-020-01011-7  0.374
2020 Santoro JD, Waltz M, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rensel M, ... Rodriguez M, et al. ediatric Multiple Sclerosis Severity Score in a Large U.S. Cohort. Neurology. PMID 32690790 DOI: 10.1212/Wnl.0000000000010414  0.342
2020 Licht-Mayer S, Campbell GR, Canizares M, Mehta AR, Gane AB, McGill K, Ghosh A, Fullerton A, Menezes N, Dean J, Dunham J, Al-Azki S, Pryce G, Zandee S, Zhao C, ... ... Rodriguez M, et al. Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis. Acta Neuropathologica. PMID 32572598 DOI: 10.1007/S00401-020-02179-X  0.343
2020 Krysko KM, Graves JS, Rensel M, Weinstock-Guttman B, Rutatangwa A, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Goyal MS, Harris Y, Krupp L, Lotze T, Mar S, ... ... Rodriguez M, et al. Real-world effectiveness of initial disease-modifying therapies in pediatric MS. Annals of Neurology. PMID 32267005 DOI: 10.1002/Ana.25737  0.32
2020 Kantarci OH, Zeydan B, Atkinson EJ, Conway BL, Castrillo-Viguera C, Rodriguez M. Relapse recovery: The forgotten variable in multiple sclerosis clinical trials. Neurology(R) Neuroimmunology & Neuroinflammation. 7. PMID 31848231 DOI: 10.1212/Nxi.0000000000000653  0.339
2019 Anderson G, Rodriguez M, Reiter RJ. Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells. International Journal of Molecular Sciences. 20. PMID 31694154 DOI: 10.3390/Ijms20215500  0.306
2019 Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, et al. miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. Annals of Clinical and Translational Neurology. 6: 1053-1061. PMID 31211169 DOI: 10.1002/Acn3.786  0.309
2019 Wilbanks B, Maher LJ, Rodriguez M. Glial cells as therapeutic targets in progressive multiple sclerosis. Expert Review of Neurotherapeutics. 1-14. PMID 31081705 DOI: 10.1080/14737175.2019.1614443  0.366
2019 Wilbanks B, Smestad J, Heider RM, Warrington AE, Rodriguez M, Maher LJ. Optimization of a 40-mer Antimyelin DNA Aptamer Identifies a 20-mer with Enhanced Properties for Potential Multiple Sclerosis Therapy. Nucleic Acid Therapeutics. PMID 30855209 DOI: 10.1089/Nat.2018.0776  0.31
2019 Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, ... ... Rodriguez M, et al. Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry. Plos Genetics. 15: e1007808. PMID 30653506 DOI: 10.1371/Journal.Pgen.1007808  0.32
2019 Fereidan-Esfahani M, Nayfeh T, Warrington A, Howe CL, Rodriguez M. IgM Natural Autoantibodies in Physiology and the Treatment of Disease. Methods in Molecular Biology (Clifton, N.J.). 1904: 53-81. PMID 30539466 DOI: 10.1007/978-1-4939-8958-4_3  0.337
2018 Mar S, Liang S, Waltz M, Casper TC, Goyal M, Greenberg B, Weinstock-Guttman B, Rodriguez M, Aaen G, Belman A, Barcellos LF, Rose J, Gorman M, Benson L, Candee M, et al. Several household chemical exposures are associated with pediatric-onset multiple sclerosis. Annals of Clinical and Translational Neurology. 5: 1513-1521. PMID 30564618 DOI: 10.1002/Acn3.663  0.325
2018 Nourbakhsh B, Rutatangwa A, Waltz M, Rensel M, Moodley M, Graves J, Casper TC, Waldman A, Belman A, Greenberg B, Goyal M, Harris Y, Kahn I, Lotze T, Mar S, ... ... Rodriguez M, et al. Heterogeneity in association of remote herpesvirus infections and pediatric MS. Annals of Clinical and Translational Neurology. 5: 1222-1228. PMID 30349857 DOI: 10.1002/Acn3.636  0.344
2018 Krysko KM, Graves J, Rensel M, Weinstock-Guttman B, Aaen G, Benson L, Chitnis T, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Rodriguez M, Rose J, Waltz M, et al. Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US. Neurology. PMID 30333163 DOI: 10.1212/Wnl.0000000000006471  0.329
2018 Conway BL, Zeydan B, Uygunoğlu U, Novotna M, Siva A, Pittock SJ, Atkinson EJ, Rodriguez M, Kantarci OH. Age is a critical determinant in recovery from multiple sclerosis relapses. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518800815. PMID 30303037 DOI: 10.1177/1352458518800815  0.311
2018 Vala M, Jordan LR, Warrington AE, Maher Iii LJ, Rodriguez M, Wittenberg NJ, Oh SH. Surface plasmon resonance sensing on naturally derived membranes: A remyelination-promoting human antibody binds myelin with extraordinary affinity. Analytical Chemistry. PMID 30231202 DOI: 10.1021/Acs.Analchem.8B02664  0.391
2018 Heider RM, Smestad JA, Lemus HN, Wilbanks B, Warrington AE, Peters JP, Rodriguez M, Maher LJ. An Assay that Predicts Efficacy for DNA Aptamers that Stimulate Remyelination in a Mouse Model of Multiple Sclerosis. Molecular Therapy. Methods & Clinical Development. 9: 270-277. PMID 29707601 DOI: 10.1016/J.Omtm.2018.03.005  0.378
2018 Perwein MK, Smestad JA, Warrington AE, Heider RM, Kaczor MW, Maher LJ, Wootla B, Kunbaz A, Rodriguez M. A Comparison of Human Natural Monoclonal Antibodies and Aptamer Conjugates for Promotion of CNS Remyelination: Where Are We Now and What Comes Next? Expert Opinion On Biological Therapy. PMID 29460650 DOI: 10.1080/14712598.2018.1441284  0.425
2018 Rahmanzadeh R, Sahraian MA, Rahmanzade R, Rodriguez M. Demyelination with preferential MAG loss: A complex message from MS paraffin blocks. Journal of the Neurological Sciences. 385: 126-130. PMID 29406891 DOI: 10.1016/J.Jns.2017.12.029  0.397
2018 Lemus HN, Warrington AE, Rodriguez M. Multiple Sclerosis: Mechanisms of Disease and Strategies for Myelin and Axonal Repair. Neurologic Clinics. 36: 1-11. PMID 29157392 DOI: 10.1016/J.Ncl.2017.08.002  0.409
2018 Kunbaz A, Warrington AE, Perwein MK, Fereidan-Esfahani M, Rodriguez M. A natural human monoclonal antibody protects from axonal injury in different CNS degenerative disease models Future Neurology. 13: 23-29. DOI: 10.2217/Fnl-2017-0027  0.33
2017 Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, et al. Examining the contributions of environmental quality to pediatric multiple sclerosis. Multiple Sclerosis and Related Disorders. 18: 164-169. PMID 29141802 DOI: 10.1016/J.Msard.2017.09.004  0.33
2017 Azary S, Schreiner T, Graves J, Waldman A, Belman A, Guttman BW, Aaen G, Tillema JM, Mar S, Hart J, Ness J, Harris Y, Krupp L, Gorman M, Benson L, ... Rodriguez M, et al. Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28993476 DOI: 10.1136/Jnnp-2017-315936  0.326
2017 Mangalam A, Shahi SK, Luckey D, Karau M, Marietta E, Luo N, Choung RS, Ju J, Sompallae R, Gibson-Corley K, Patel R, Rodriguez M, David C, Taneja V, Murray J. Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease. Cell Reports. 20: 1269-1277. PMID 28793252 DOI: 10.1016/J.Celrep.2017.07.031  0.381
2017 Pakpoor J, Seminatore B, Graves JS, Schreiner T, Waldman AT, Lotze TE, Belman A, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, McDonald JC, Hart J, Ness JM, Harris Y, ... ... Rodriguez M, et al. Dietary factors and pediatric multiple sclerosis: A case-control study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517713343. PMID 28608728 DOI: 10.1177/1352458517713343  0.347
2017 Cui QL, Khan D, Rone M, Rao V, Johnson RM, Lin YH, Bilodeau PA, Hall JA, Rodriguez M, Kennedy TE, Ludwin SK, Antel JP. Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis? Annals of Neurology. PMID 28470695 DOI: 10.1002/Ana.24944  0.354
2017 Bourne T, Waltz M, Casper TC, Kavak K, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Graves J, Greenberg B, Gorman M, Harris Y, Krupp L, Lotze T, ... ... Rodriguez M, et al. Evaluating the association of allergies with multiple sclerosis susceptibility risk and disease activity in a pediatric population. Journal of the Neurological Sciences. 375: 371-375. PMID 28320170 DOI: 10.1016/J.Jns.2017.02.041  0.353
2017 Lemus HN, Warrington AE, Denic A, Wootla B, Rodriguez M. Treatment with a recombinant human IgM that recognizes PSA-NCAM preserves brain pathology in MOG-induced experimental autoimmune encephalomyelitis. Human Antibodies. PMID 28269761 DOI: 10.3233/Hab-170313  0.416
2017 Zeydan B, Rodriguez M, Kantarci OH. Timing of Future Remyelination Therapies and Their Potential to Stop Multiple Sclerosis Progression. Advances in Experimental Medicine and Biology. 958: 161-170. PMID 28093713 DOI: 10.1007/978-3-319-47861-6_10  0.386
2016 Wootla B, Denic A, Watzlawik JO, Warrington AE, Zoecklein LJ, Papke-Norton LM, David C, Rodriguez M. Human class I major histocompatibility complex alleles determine central nervous system injury versus repair. Journal of Neuroinflammation. 13: 293. PMID 27855706 DOI: 10.1186/S12974-016-0759-4  0.317
2016 Dasari H, Wootla B, Warrington AE, Rodriguez M. Concomitant Use of Neuroprotective Drugs in Neuro Rehabilitation of Multiple Sclerosis. International Journal of Physical Medicine & Rehabilitation. 4. PMID 27595123 DOI: 10.4172/2329-9096.1000348  0.389
2016 Watzlawik JO, Kahoud RJ, Wootla B, Painter MM, Warrington AE, Carey WA, Rodriguez M. Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study. Journal of Visualized Experiments : Jove. PMID 27404858 DOI: 10.3791/54139  0.359
2016 Belman AL, Krupp LB, Olsen CS, Rose JW, Aaen G, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze T, Ness J, Rodriguez M, Tillema JM, Waubant E, et al. Characteristics of Children and Adolescents With Multiple Sclerosis. Pediatrics. PMID 27358474 DOI: 10.1542/Peds.2016-0120  0.316
2016 Mangalam AK, Rattan R, Suhail H, Singh J, Hoda MN, Deshpande M, Fulzele S, Denic A, Shridhar V, Kumar A, Viollet B, Rodriguez M, Giri S. AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage-Th17 Axis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27354217 DOI: 10.4049/Jimmunol.1501549  0.309
2016 Chen J, Chia N, Kalari KR, Yao JZ, Novotna M, Soldan MM, Luckey DH, Marietta EV, Jeraldo PR, Chen X, Weinshenker BG, Rodriguez M, Kantarci OH, Nelson H, Murray JA, et al. Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls. Scientific Reports. 6: 28484. PMID 27346372 DOI: 10.1038/Srep28484  0.339
2016 Nourbakhsh B, Graves J, Casper TC, Lulu S, Waldman A, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Ness J, Rubin J, Krupp L, Gorman M, ... ... Rodriguez M, et al. Dietary salt intake and time to relapse in paediatric multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27343226 DOI: 10.1136/Jnnp-2016-313410  0.332
2016 Wootla B, Denic A, Warrington AE, Rodriguez M. A monoclonal natural human IgM protects axons in the absence of remyelination. Journal of Neuroinflammation. 13: 94. PMID 27126523 DOI: 10.1186/S12974-016-0561-3  0.417
2016 McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, ... ... Rodriguez M, et al. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis. Multiple Sclerosis and Related Disorders. 6: 87-92. PMID 27063630 DOI: 10.1016/J.Msard.2016.02.011  0.324
2016 Wootla B, Watzlawik JO, Stavropoulos N, Wittenberg NJ, Dasari H, Abdelrahim MA, Henley JR, Oh SH, Warrington AE, Rodriguez M. Recent Advances in Monoclonal Antibody Therapies for Multiple Sclerosis. Expert Opinion On Biological Therapy. PMID 26914737 DOI: 10.1517/14712598.2016.1158809  0.372
2016 Watzlawik JO, Wootla B, Rodriguez M. Tryptophan Catabolites and Their Impact on Multiple Sclerosis Progression. Current Pharmaceutical Design. 22: 1049-59. PMID 26899126 DOI: 10.2174/1381612822666151215095940  0.366
2015 Painter MM, Morrison JH, Zoecklein LJ, Rinkoski TA, Watzlawik JO, Papke LM, Warrington AE, Bieber AJ, Matchett WE, Turkowski KL, Poeschla EM, Rodriguez M. Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity. Plos Pathogens. 11: e1005311. PMID 26633895 DOI: 10.1371/Journal.Ppat.1005311  0.33
2015 Poisson LM, Suhail H, Singh J, Datta I, Denic A, Labuzek K, Hoda MN, Shankar A, Kumar A, Cerghet M, Elias S, Mohney RP, Rodriguez M, Rattan R, Mangalam AK, et al. Untargeted plasma metabolomics identifies endogenous metabolite with drug-like properties in chronic animal model of multiple sclerosis. The Journal of Biological Chemistry. PMID 26546682 DOI: 10.1074/Jbc.M115.679068  0.344
2015 Wootla B, Denic A, Watzlawik JO, Warrington AE, Rodriguez M. Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease. Molecular Neurobiology. PMID 26409478 DOI: 10.1007/S12035-015-9436-3  0.391
2015 Wootla B, Watzlawik JO, Warrington AE, Wittenberg NJ, Denic A, Xu X, Jordan LR, Papke LM, Zoecklein LJ, Pierce ML, Oh SH, Kantarci OH, Rodriguez M. Naturally Occurring Monoclonal Antibodies and Their Therapeutic Potential for Neurologic Diseases. Jama Neurology. PMID 26389734 DOI: 10.1001/Jamaneurol.2015.2188  0.32
2015 Novotna M, Paz Soldán MM, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M, et al. Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis. Neurology. 85: 722-9. PMID 26208962 DOI: 10.1212/Wnl.0000000000001856  0.363
2015 Xu X, Denic A, Jordan LR, Wittenberg NJ, Warrington AE, Wootla B, Papke LM, Zoecklein LJ, Yoo D, Shaver J, Oh SH, Pease LR, Rodriguez M. A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis. Disease Models & Mechanisms. PMID 26035393 DOI: 10.1242/Dmm.020727  0.351
2015 Watzlawik JO, Kahoud RJ, O'Toole RJ, White KA, Ogden AR, Painter MM, Wootla B, Papke LM, Denic A, Weimer JM, Carey WA, Rodriguez M. Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice. Plos One. 10: e0128007. PMID 26020269 DOI: 10.1371/Journal.Pone.0128007  0.345
2015 Wootla B, Denic A, Watzlawik JO, Warrington AE, Rodriguez M. A single dose of a neuron-binding human monoclonal antibody improves brainstem NAA concentrations, a biomarker for density of spinal cord axons, in a model of progressive multiple sclerosis. Journal of Neuroinflammation. 12: 83. PMID 25924771 DOI: 10.1186/S12974-015-0303-Y  0.405
2015 Watzlawik JO, Kahoud RJ, Ng S, Painter MM, Papke LM, Zoecklein L, Wootla B, Warrington AE, Carey WA, Rodriguez M. Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders. Journal of Neurochemistry. PMID 25866077 DOI: 10.1111/Jnc.13121  0.416
2015 Anderson G, Rodriguez M. Multiple sclerosis: the role of melatonin and N-acetylserotonin. Multiple Sclerosis and Related Disorders. 4: 112-23. PMID 25787187 DOI: 10.1016/J.Msard.2014.12.001  0.352
2015 Anderson G, Maes M, Markus RP, Rodriguez M. Ebola virus: melatonin as a readily available treatment option. Journal of Medical Virology. 87: 537-43. PMID 25611054 DOI: 10.1002/Jmv.24130  0.305
2015 Perschbacher K, Smestad JA, Peters JP, Standiford MM, Denic A, Wootla B, Warrington AE, Rodriguez M, Maher LJ. Quantitative PCR analysis of DNA aptamer pharmacokinetics in mice. Nucleic Acid Therapeutics. 25: 11-9. PMID 25536292 DOI: 10.1089/Nat.2014.0515  0.3
2015 Paz Soldán MM, Novotna M, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Weinshenker BG, Rodriguez M, Kantarci OH. Relapses and disability accumulation in progressive multiple sclerosis. Neurology. 84: 81-8. PMID 25398229 DOI: 10.1212/Wnl.0000000000001094  0.359
2015 Tillema J, Hopkins S, Rodriguez M, Leach J. Imaging of multiple sclerosis and related acquired demyelinating disorders in childhood Journal of Pediatric Neuroradiology. 2: 057-072. DOI: 10.3233/Pnr-13047  0.316
2015 Wootla B, Denic A, Warrington AE, Macura SI, Rodriguez M. Antibody-mediated oligodendrocyte remyelination protects axons and restores axonal transport in progressive demyelinating disease Journal of the Neurological Sciences. 357. DOI: 10.1016/J.Jns.2015.08.134  0.343
2014 Mangalam AK, Luo N, Luckey D, Papke L, Hubbard A, Wussow A, Smart M, Giri S, Rodriguez M, David C. Absence of IFN-γ increases brain pathology in experimental autoimmune encephalomyelitis-susceptible DRB1*0301.DQ8 HLA transgenic mice through secretion of proinflammatory cytokine IL-17 and induction of pathogenic monocytes/microglia into the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 193: 4859-70. PMID 25339670 DOI: 10.4049/Jimmunol.1302008  0.381
2014 Rodriguez M, Pease LR, David CS. Immune-mediated injury of virus-infected oligodendrocytes A model of multiple sclerosis. Immunology Today. 7: 359-63. PMID 25291330 DOI: 10.1016/0167-5699(86)90025-3  0.4
2014 Panos M, Christophi GP, Rodriguez M, Scarisbrick IA. Differential expression of multiple kallikreins in a viral model of multiple sclerosis points to unique roles in the innate and adaptive immune response. Biological Chemistry. 395: 1063-73. PMID 25153387 DOI: 10.1515/Hsz-2014-0141  0.441
2013 Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, et al. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. Bmc Neurology. 13: 173. PMID 24225378 DOI: 10.1186/1471-2377-13-173  0.319
2013 Watzlawik JO, Wootla B, Painter MM, Warrington AE, Rodriguez M. Cellular targets and mechanistic strategies of remyelination-promoting IgMs as part of the naturally occurring autoantibody repertoire. Expert Review of Neurotherapeutics. 13: 1017-29. PMID 24053345 DOI: 10.1586/14737175.2013.835601  0.346
2013 Denic A, Wootla B, Rodriguez M. CD8(+) T cells in multiple sclerosis. Expert Opinion On Therapeutic Targets. 17: 1053-66. PMID 23829711 DOI: 10.1517/14728222.2013.815726  0.334
2013 Wootla B, Watzlawik JO, Denic A, Rodriguez M. The road to remyelination in demyelinating diseases: current status and prospects for clinical treatment. Expert Review of Clinical Immunology. 9: 535-49. PMID 23730884 DOI: 10.1586/Eci.13.37  0.417
2013 Watzlawik JO, Warrington AE, Rodriguez M. PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation. Plos One. 8: e55149. PMID 23383310 DOI: 10.1371/Journal.Pone.0055149  0.407
2013 Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, James JA. Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 891-5. PMID 23232601 DOI: 10.1177/1352458512469693  0.359
2013 Xu X, Denic A, Warrington AE, Bieber AJ, Rodriguez M. Therapeutics to promote CNS repair: a natural human neuron-binding IgM regulates membrane-raft dynamics and improves motility in a mouse model of multiple sclerosis. Journal of Clinical Immunology. 33: S50-6. PMID 22990667 DOI: 10.1007/S10875-012-9795-8  0.36
2013 Tutuncu M, Tang J, Zeid NA, Kale N, Crusan DJ, Atkinson EJ, Siva A, Pittock SJ, Pirko I, Keegan BM, Lucchinetti CF, Noseworthy JH, Rodriguez M, Weinshenker BG, Kantarci OH. Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 188-98. PMID 22736750 DOI: 10.1177/1352458512451510  0.35
2012 Warrington AE, Van Keulen V, Pease LR, Rodriguez M. Naturally occurring antibodies as therapeutics for neurologic disease: can human monoclonal IgMs replace the limited resource IVIG? Advances in Experimental Medicine and Biology. 750: 44-55. PMID 22903665 DOI: 10.1007/978-1-4614-3461-0_4  0.373
2012 Wittenberg NJ, Im H, Xu X, Wootla B, Watzlawik J, Warrington AE, Rodriguez M, Oh SH. High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance. Analytical Chemistry. 84: 6031-9. PMID 22762372 DOI: 10.1021/Ac300819A  0.33
2012 Nastasijevic B, Wright BR, Smestad J, Warrington AE, Rodriguez M, Maher LJ. Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis. Plos One. 7: e39595. PMID 22761835 DOI: 10.1371/Journal.Pone.0039595  0.44
2012 Wootla B, Eriguchi M, Rodriguez M. Is multiple sclerosis an autoimmune disease? Autoimmune Diseases. 2012: 969657. PMID 22666554 DOI: 10.1155/2012/969657  0.402
2012 Mangalam AK, Luckey D, Giri S, Smart M, Pease LR, Rodriguez M, David CS. Two discreet subsets of CD8 T cells modulate PLP 91-110 induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice Journal of Autoimmunity. 38: 344-353. PMID 22459490 DOI: 10.1016/J.Jaut.2012.02.004  0.311
2012 Wootla B, Denic A, Warrington AE, Rodriguez M. Need for a paradigm shift in therapeutic approaches to CNS injury. Expert Review of Neurotherapeutics. 12: 409-20. PMID 22449213 DOI: 10.1586/Ern.12.24  0.337
2012 Pavelko KD, Mendez-Fernandez Y, Bell MP, Hansen MJ, Johnson AJ, David CS, Rodriguez M, Pease LR. Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity. Plos Pathogens. 8: e1002541. PMID 22383876 DOI: 10.1371/Journal.Ppat.1002541  0.357
2012 Scarisbrick IA, Yoon H, Panos M, Larson N, Blaber SI, Blaber M, Rodriguez M. Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis. Brain Pathology (Zurich, Switzerland). 22: 709-22. PMID 22335454 DOI: 10.1111/J.1750-3639.2012.00577.X  0.388
2012 Denic A, Pirko I, Wootla B, Bieber A, Macura S, Rodriguez M. Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis. Brain Pathology (Zurich, Switzerland). 22: 698-708. PMID 22335434 DOI: 10.1111/J.1750-3639.2012.00576.X  0.4
2012 Paz Soldán MM, Pittock SJ, Weigand SD, Yawn BP, Rodriguez M. Statin therapy and multiple sclerosis disability in a population-based cohort. Multiple Sclerosis (Houndmills, Basingstoke, England). 18: 358-63. PMID 21908483 DOI: 10.1177/1352458511421920  0.364
2012 Graves J, Krupp L, Weinstock-Guttman B, Strober J, Belman A, Yeh EA, Ness J, Gorman M, Rodriguez M, Chitnis T, Waubant E. EBV, CMV, and HSV IgG Titers Are Not Predictive of Subsequent Relapse Risk in Pediatric Multiple Sclerosis (P02.096) Neurology. 78: P02.096-P02.096. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.096  0.369
2011 Denic A, Macura SI, Warrington AE, Pirko I, Grossardt BR, Pease LR, Rodriguez M. A single dose of neuron-binding human monoclonal antibody improves spontaneous activity in a murine model of demyelination. Plos One. 6: e26001. PMID 22022490 DOI: 10.1371/Journal.Pone.0026001  0.353
2011 Wootla B, Denic A, Keegan BM, Winters JL, Astapenko D, Warrington AE, Bieber AJ, Rodriguez M. Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis. Neurology Research International. 2011: 780712. PMID 21961063 DOI: 10.1155/2011/780712  0.362
2011 Xu X, Warrington AE, Bieber AJ, Rodriguez M. Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network. Cns Drugs. 25: 555-73. PMID 21699269 DOI: 10.2165/11587830-000000000-00000  0.366
2011 Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Chabas D, Strober J, McDonald J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, et al. Common viruses associated with lower pediatric multiple sclerosis risk. Neurology. 76: 1989-95. PMID 21646624 DOI: 10.1212/Wnl.0B013E31821E552A  0.351
2011 Wootla B, Lacroix-Desmazes S, Warrington AE, Bieber AJ, Kaveri SV, Rodriguez M. Autoantibodies with enzymatic properties in human autoimmune diseases. Journal of Autoimmunity. 37: 144-50. PMID 21624820 DOI: 10.1016/J.Jaut.2011.05.007  0.336
2011 Chitnis T, Krupp L, Yeh A, Rubin J, Kuntz N, Strober JB, Chabas D, Weinstock-Guttmann B, Ness J, Rodriguez M, Waubant E. Pediatric multiple sclerosis. Neurologic Clinics. 29: 481-505. PMID 21439455 DOI: 10.1016/J.Ncl.2011.01.004  0.323
2011 Magaña SM, Keegan BM, Weinshenker BG, Erickson BJ, Pittock SJ, Lennon VA, Rodriguez M, Thomsen K, Weigand S, Mandrekar J, Linbo L, Lucchinetti CF. Beneficial plasma exchange response in central nervous system inflammatory demyelination. Archives of Neurology. 68: 870-8. PMID 21403003 DOI: 10.1001/Archneurol.2011.34  0.331
2011 Denic A, Zoecklein L, Kerkvliet J, Papke L, Edukulla R, Warrington A, Bieber A, Pease LR, David CS, Rodriguez M. Transgenic expression of viral capsid proteins predisposes to axonal injury in a murine model of multiple sclerosis. Brain Pathology (Zurich, Switzerland). 21: 501-15. PMID 21314744 DOI: 10.1111/J.1750-3639.2011.00474.X  0.401
2011 Yeh EA, Waubant E, Krupp LB, Ness J, Chitnis T, Kuntz N, Ramanathan M, Belman A, Chabas D, Gorman MP, Rodriguez M, Rinker JR, Weinstock-Guttman B. Multiple sclerosis therapies in pediatric patients with refractory multiple sclerosis. Archives of Neurology. 68: 437-44. PMID 21149803 DOI: 10.1001/Archneurol.2010.325  0.325
2011 Denic A, Johnson AJ, Bieber AJ, Warrington AE, Rodriguez M, Pirko I. The relevance of animal models in multiple sclerosis research. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 18: 21-9. PMID 20537877 DOI: 10.1016/J.Pathophys.2010.04.004  0.42
2010 Kerkvliet J, Papke L, Rodriguez M. Antiviral effects of a transgenic RNA-dependent RNA polymerase. Journal of Virology. 85: 621-5. PMID 20962089 DOI: 10.1128/Jvi.01626-10  0.303
2010 Deb C, Lafrance-Corey RG, Schmalstieg WF, Sauer BM, Wang H, German CL, Windebank AJ, Rodriguez M, Howe CL. CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis. Plos One. 5: e12478. PMID 20814579 DOI: 10.1371/Journal.Pone.0012478  0.355
2010 Warrington AE, Rodriguez M. Method of identifying natural antibodies for remyelination. Journal of Clinical Immunology. S50-5. PMID 20387101 DOI: 10.1007/S10875-010-9406-5  0.37
2010 Watzlawik J, Warrington AE, Rodriguez M. Importance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination. Expert Review of Neurotherapeutics. 10: 441-57. PMID 20187865 DOI: 10.1586/Ern.10.13  0.397
2010 Kuntz NL, Chabas D, Weinstock-Guttman B, Chitnis T, Yeh EA, Krupp L, Ness J, Rodriguez M, Waubant E. Treatment of multiple sclerosis in children and adolescents. Expert Opinion On Pharmacotherapy. 11: 505-20. PMID 20163265 DOI: 10.1517/14656560903527218  0.32
2010 Chabas D, Ness J, Belman A, Yeh EA, Kuntz N, Gorman MP, Strober JB, De Kouchkovsky I, McCulloch C, Chitnis T, Rodriguez M, Weinstock-Guttman B, Krupp LB, Waubant E. Younger children with MS have a distinct CSF inflammatory profile at disease onset. Neurology. 74: 399-405. PMID 20124205 DOI: 10.1212/Wnl.0B013E3181Ce5Db0  0.344
2010 Bieber AJ, Suwansrinon K, Kerkvliet J, Zhang W, Pease LR, Rodriguez M. Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair. Proceedings of the National Academy of Sciences of the United States of America. 107: 792-7. PMID 20080754 DOI: 10.1073/Pnas.0906589107  0.375
2010 Schwartz-Albiez R, Monteiro RC, Rodriguez M, Binder CJ, Shoenfeld Y. Natural antibodies, intravenous immunoglobulin and their role in autoimmunity, cancer and inflammation. Clinical and Experimental Immunology. 43-50. PMID 19883423 DOI: 10.1111/J.1365-2249.2009.04026.X  0.317
2009 Wright BR, Warrington AE, Edberg DD, Edberg DE, Rodriguez M. Cellular mechanisms of central nervous system repair by natural autoreactive monoclonal antibodies. Archives of Neurology. 66: 1456-9. PMID 20008649 DOI: 10.1001/Archneurol.2009.262  0.355
2009 Rodriguez M. Have we finally identified an autoimmune demyelinating disease? Annals of Neurology. 66: 572-573. PMID 19938069 DOI: 10.1002/Ana.21838  0.349
2009 Denic A, Bieber A, Warrington A, Mishra PK, Macura S, Rodriguez M. Brainstem 1H nuclear magnetic resonance (NMR) spectroscopy: marker of demyelination and repair in spinal cord. Annals of Neurology. 66: 559-64. PMID 19816926 DOI: 10.1002/Ana.21758  0.359
2009 Kerkvliet J, Zoecklein L, Papke L, Denic A, Bieber AJ, Pease LR, David CS, Rodriguez M. Transgenic expression of the 3D polymerase inhibits Theiler's virus infection and demyelination. Journal of Virology. 83: 12279-89. PMID 19759133 DOI: 10.1128/Jvi.00664-09  0.338
2009 Deb C, Lafrance-Corey RG, Zoecklein L, Papke L, Rodriguez M, Howe CL. Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 68: 1037-48. PMID 19680139 DOI: 10.1097/Nen.0B013E3181B5417E  0.405
2009 Rodriguez M, Warrington AE, Pease LR. Invited article: human natural autoantibodies in the treatment of neurologic disease. Neurology. 72: 1269-76. PMID 19349608 DOI: 10.1212/01.Wnl.0000345662.05861.E4  0.35
2009 Mangalam A, Luckey D, Basal E, Jackson M, Smart M, Rodriguez M, David C. HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 182: 5131-9. PMID 19342694 DOI: 10.4049/Jimmunol.0803918  0.383
2009 Rodriguez M, Zoecklein L, Papke L, Gamez J, Denic A, Macura S, Howe C. Tumor necrosis factor α is reparative via TNFR1 in the hippocampus and via TNFR2 in the striatum after virus-induced encephalitis Brain Pathology. 19: 12-26. PMID 18422761 DOI: 10.1111/J.1750-3639.2008.00151.X  0.333
2008 Radhakrishnan S, Arneson LN, Upshaw JL, Howe CL, Felts SJ, Colonna M, Leibson PJ, Rodriguez M, Pease LR. TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 7863-72. PMID 19017976 DOI: 10.4049/Jimmunol.181.11.7863  0.302
2008 Scarisbrick IA, Linbo R, Vandell AG, Keegan M, Blaber SI, Blaber M, Sneve D, Lucchinetti CF, Rodriguez M, Diamandis EP. Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biological Chemistry. 389: 739-45. PMID 18627300 DOI: 10.1515/Bc.2008.085  0.371
2008 Pirko I, Suidan GL, Rodriguez M, Johnson AJ. Acute hemorrhagic demyelination in a murine model of multiple sclerosis. Journal of Neuroinflammation. 5: 31. PMID 18606015 DOI: 10.1186/1742-2094-5-31  0.398
2008 Mangalam A, Luckey D, Basal E, Behrens M, Rodriguez M, David C. HLA-DQ6 (DQB1*0601)-restricted T cells protect against experimental autoimmune encephalomyelitis in HLA-DR3.DQ6 double-transgenic mice by generating anti-inflammatory IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 180: 7747-56. PMID 18490779 DOI: 10.4049/Jimmunol.180.11.7747  0.385
2008 Rodriguez M, Zoecklein L, Kerkvliet JG, Pavelko KD, Papke L, Howe CL, Pease LR, David C. Human HLA-DR transgenes protect mice from fatal virus-induced encephalomyelitis and chronic demyelination. Journal of Virology. 82: 3369-80. PMID 18234804 DOI: 10.1128/Jvi.02243-07  0.384
2007 Howe CL, Ure D, Adelson JD, LaFrance-Corey R, Johnson A, Rodriguez M. CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination. Journal of Neuroimmunology. 188: 13-21. PMID 17493690 DOI: 10.1016/J.Jneuroim.2007.04.005  0.363
2007 Rodriguez M. Effectors of demyelination and remyelination in the CNS: implications for multiple sclerosis. Brain Pathology (Zurich, Switzerland). 17: 219-29. PMID 17388953 DOI: 10.1111/J.1750-3639.2007.00065.X  0.43
2007 Pavelko KD, Pease LR, David CS, Rodriguez M. Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination. Brain Pathology (Zurich, Switzerland). 17: 184-96. PMID 17388949 DOI: 10.1111/J.1750-3639.2007.00062.X  0.397
2007 Mangalam A, Rodriguez M, David C. A new humanized HLA transgenic mouse model of multiple sclerosis expressing class II on mouse CD4 T cells. Annals of the New York Academy of Sciences. 1103: 112-7. PMID 17376829 DOI: 10.1196/Annals.1394.005  0.315
2007 Warrington AE, Bieber AJ, Ciric B, Pease LR, Van Keulen V, Rodriguez M. A recombinant human IgM promotes myelin repair after a single, very low dose. Journal of Neuroscience Research. 85: 967-76. PMID 17304578 DOI: 10.1002/Jnr.21217  0.386
2007 Mangalam A, Rodriguez M, David C. Role of MHC class II expressing CD4+ T cells in proteolipid protein(91-110)-induced EAE in HLA-DR3 transgenic mice. European Journal of Immunology. 36: 3356-70. PMID 17125142 DOI: 10.1002/Eji.200636217  0.331
2007 Howe CL, Adelson JD, Rodriguez M. Absence of perforin expression confers axonal protection despite demyelination. Neurobiology of Disease. 25: 354-9. PMID 17112732 DOI: 10.1016/J.Nbd.2006.10.001  0.385
2007 Lassmann H, Rodriguez M. SYMPOSIUM: New Disease Mechanisms in Multiple Sclerosis Brain Pathology. 17: 209-209. DOI: 10.1111/J.1750-3639.2007.00063.X  0.332
2006 Miller RC, Lachance DH, Lucchinetti CF, Keegan BM, Gavrilova RH, Brown PD, Weinshenker BG, Rodriguez M. Multiple sclerosis, brain radiotherapy, and risk of neurotoxicity: the Mayo Clinic experience. International Journal of Radiation Oncology, Biology, Physics. 66: 1178-86. PMID 16965867 DOI: 10.1016/J.Ijrobp.2006.06.014  0.312
2006 Pittock SJ, Noseworthy JH, Rodriguez M. MRI findings in benign multiple sclerosis are variable. Journal of Neurology. 254: 539-41. PMID 16944348 DOI: 10.1007/S00415-006-0276-Y  0.308
2006 Buenz EJ, Rodriguez M, Howe CL. Disrupted spatial memory is a consequence of picornavirus infection. Neurobiology of Disease. 24: 266-73. PMID 16919964 DOI: 10.1016/J.Nbd.2006.07.003  0.306
2006 Wingerchuk DM, Rodriguez M. Premenstrual multiple sclerosis pseudoexacerbations: Role of body temperature and prevention with aspirin. Archives of Neurology. 63: 1005-8. PMID 16831971 DOI: 10.1001/Archneur.63.7.1005  0.325
2006 Scarisbrick IA, Blaber SI, Tingling JT, Rodriguez M, Blaber M, Christophi GP. Potential scope of action of tissue kallikreins in CNS immune-mediated disease. Journal of Neuroimmunology. 178: 167-76. PMID 16824622 DOI: 10.1016/J.Jneuroim.2006.05.022  0.328
2006 Pittock SJ, Weinshenker BG, Noseworthy JH, Lucchinetti CF, Keegan M, Wingerchuk DM, Carter J, Shuster E, Rodriguez M. Not every patient with multiple sclerosis should be treated at time of diagnosis. Archives of Neurology. 63: 611-4. PMID 16606780 DOI: 10.1001/Archneur.63.4.611  0.341
2006 Van Keulen VP, Ciric B, Radhakrishnan S, Heckman KL, Mitsunaga Y, Iijima K, Kita H, Rodriguez M, Pease LR. Immunomodulation using the recombinant monoclonal human B7-DC cross-linking antibody rHIgM12. Clinical and Experimental Immunology. 143: 314-21. PMID 16412056 DOI: 10.1111/J.1365-2249.2005.02992.X  0.318
2006 Rodriguez M, Zoecklein L, Gamez JD, Pavelko KD, Papke LM, Nakane S, Howe C, Radhakrishnan S, Hansen MJ, David CS, Warrington AE, Pease LR. STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 343-5. PMID 16352646 DOI: 10.1096/Fj.05-4650Fje  0.422
2005 Pittock SJ, McClelland RL, Achenbach SJ, Konig F, Bitsch A, Brück W, Lassmann H, Parisi JE, Scheithauer BW, Rodriguez M, Weinshenker BG, Lucchinetti CF. Clinical course, pathological correlations, and outcome of biopsy proved inflammatory demyelinating disease. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 1693-7. PMID 16291895 DOI: 10.1136/Jnnp.2004.060624  0.386
2005 Khare M, Mangalam A, Rodriguez M, David CS. HLA DR and DQ interaction in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in HLA class II transgenic mice. Journal of Neuroimmunology. 169: 1-12. PMID 16194572 DOI: 10.1016/J.Jneuroim.2005.07.023  0.374
2005 Keegan M, König F, McClelland R, Brück W, Morales Y, Bitsch A, Panitch H, Lassmann H, Weinshenker B, Rodriguez M, Parisi J, Lucchinetti CF. Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet (London, England). 366: 579-82. PMID 16099294 DOI: 10.1016/S0140-6736(05)67102-4  0.309
2005 Ure DR, Lane TE, Liu MT, Rodriguez M. Neutralization of chemokines RANTES and MIG increases virus antigen expression and spinal cord pathology during Theiler's virus infection. International Immunology. 17: 569-79. PMID 15824069 DOI: 10.1093/Intimm/Dxh236  0.382
2005 Block MS, Mendez-Fernandez YV, Van Keulen VP, Hansen MJ, Allen KS, Taboas AL, Rodriguez M, Pease LR. Inability of bm14 mice to respond to Theiler's murine encephalomyelitis virus is caused by defective antigen presentation, not repertoire selection. Journal of Immunology (Baltimore, Md. : 1950). 174: 2756-62. PMID 15728484 DOI: 10.4049/Jimmunol.174.5.2756  0.312
2005 Bieber AJ, Ure DR, Rodriguez M. Genetically dominant spinal cord repair in a murine model of chronic progressive multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 64: 46-57. PMID 15715084 DOI: 10.1093/Jnen/64.1.46  0.398
2005 Mendez-Fernandez YV, Hansen MJ, Rodriguez M, Pease LR. Anatomical and cellular requirements for the activation and migration of virus-specific CD8+ T cells to the brain during Theiler's virus infection. Journal of Virology. 79: 3063-70. PMID 15709026 DOI: 10.1128/Jvi.79.5.3063-3070.2005  0.322
2005 Pittock SJ, Mayr WT, McClelland RL, Jorgensen NW, Weigand SD, Noseworthy JH, Rodriguez M. Disability profile of MS did not change over 10 years in a population-based prevalence cohort. Neurology. 62: 601-6. PMID 14981177 DOI: 10.1212/Wnl.62.4.601  0.315
2004 Christophi GP, Isackson PJ, Blaber S, Blaber M, Rodriguez M, Scarisbrick IA. Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. Journal of Neurochemistry. 91: 1439-49. PMID 15584920 DOI: 10.1111/J.1471-4159.2004.02826.X  0.317
2004 Pirko I, Ciric B, Gamez J, Bieber AJ, Warrington AE, Johnson AJ, Hanson DP, Pease LR, Macura SI, Rodriguez M. A human antibody that promotes remyelination enters the CNS and decreases lesion load as detected by T2-weighted spinal cord MRI in a virus-induced murine model of MS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1577-9. PMID 15319372 DOI: 10.1096/Fj.04-2026Fje  0.353
2004 Pittock SJ, McClelland RL, Mayr WT, Jorgensen NW, Weinshenker BG, Noseworthy J, Rodriguez M. Clinical implications of benign multiple sclerosis: a 20-year population-based follow-up study. Annals of Neurology. 56: 303-6. PMID 15293286 DOI: 10.1002/Ana.20197  0.338
2004 Lin X, Ma X, Rodriguez M, Roos RP. CD4+ T cells are important for clearance of DA strain of TMEV from the central nervous system of SJL/J mice. International Immunology. 16: 1237-40. PMID 15262897 DOI: 10.1093/Intimm/Dxh125  0.329
2004 Warrington AE, Bieber AJ, Van Keulen V, Ciric B, Pease LR, Rodriguez M. Neuron-binding human monoclonal antibodies support central nervous system neurite extension. Journal of Neuropathology and Experimental Neurology. 63: 461-73. PMID 15198125 DOI: 10.1093/Jnen/63.5.461  0.342
2004 Pittock SJ, Mayr WT, McClelland RL, Jorgensen NW, Weigand SD, Noseworthy JH, Rodriguez M. Quality of life is favorable for most patients with multiple sclerosis: a population-based cohort study. Archives of Neurology. 61: 679-86. PMID 15148144 DOI: 10.1001/Archneur.61.5.679  0.313
2004 Blaber SI, Ciric B, Christophi GP, Bernett MJ, Blaber M, Rodriguez M, Scarisbrick IA. Targeting kallikrein 6 proteolysis attenuates CNS inflammatory disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 920-2. PMID 15033932 DOI: 10.1096/Fj.03-1212Fje  0.396
2004 Höftberger R, Aboul-Enein F, Brueck W, Lucchinetti C, Rodriguez M, Schmidbauer M, Jellinger K, Lassmann H. Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions. Brain Pathology (Zurich, Switzerland). 14: 43-50. PMID 14997936 DOI: 10.1111/J.1750-3639.2004.Tb00496.X  0.389
2004 Pirko I, Gamez J, Johnson AJ, Macura SI, Rodriguez M. Dynamics of MRI lesion development in an animal model of viral-induced acute progressive CNS demyelination. Neuroimage. 21: 576-82. PMID 14980559 DOI: 10.1016/J.Neuroimage.2003.09.037  0.319
2004 Pirko I, Johnson A, Gamez J, Macura SI, Rodriguez M. Disappearing "T1 black holes" in an animal model of multiple sclerosis. Frontiers in Bioscience : a Journal and Virtual Library. 9: 1222-7. PMID 14977539 DOI: 10.2741/1322  0.35
2004 Mangalam AK, Khare M, Krco C, Rodriguez M, David C. Identification of T cell epitopes on human proteolipid protein and induction of experimental autoimmune encephalomyelitis in HLA class II-transgenic mice. European Journal of Immunology. 34: 280-90. PMID 14971054 DOI: 10.1002/Eji.200324597  0.374
2004 Kumar N, Rodriguez M. Scleromyxedema in a patient with multiple sclerosis and monoclonal gammopathy on interferon beta-1a. Multiple Sclerosis (Houndmills, Basingstoke, England). 10: 85-6. PMID 14760958 DOI: 10.1191/1352458504Ms987Cr  0.362
2004 Howe CL, Bieber AJ, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiology of Disease. 15: 120-31. PMID 14751777 DOI: 10.1016/J.Nbd.2003.09.002  0.4
2004 Njenga MK, Marques C, Rodriguez M. The role of cellular immune response in Theiler's virus-induced central nervous system demyelination. Journal of Neuroimmunology. 147: 73-7. PMID 14741431 DOI: 10.1016/J.Jneuroim.2003.10.042  0.395
2004 Pittock SJ, Mayr WT, McClelland RL, Jorgensen NW, Weigand SD, Noseworthy JH, Weinshenker BG, Rodriguez M. Change in MS-related disability in a population-based cohort: a 10-year follow-up study. Neurology. 62: 51-9. PMID 14718697 DOI: 10.1212/01.Wnl.0000101724.93433.00  0.322
2004 Ciric B, Van Keulen V, Paz Soldan M, Rodriguez M, Pease LR. Antibody-mediated remyelination operates through mechanism independent of immunomodulation. Journal of Neuroimmunology. 146: 153-61. PMID 14698858 DOI: 10.1016/J.Jneuroim.2003.11.002  0.363
2004 Mayr WT, Pittock SJ, McClelland RL, Jorgensen NW, Noseworthy JH, Rodriguez M. Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000. Neurology. 61: 1373-7. PMID 14638958 DOI: 10.1212/01.Wnl.0000094316.90240.Eb  0.311
2004 Pirko I, Johnson A, Ciric B, Gamez J, Macura SI, Pease LR, Rodriguez M. In vivo magnetic resonance imaging of immune cells in the central nervous system with superparamagnetic antibodies. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 179-82. PMID 14630708 DOI: 10.1096/Fj.02-1124Fje  0.34
2003 Ciric B, Howe CL, Paz Soldan M, Warrington AE, Bieber AJ, Van Keulen V, Rodriguez M, Pease LR. Human monoclonal IgM antibody promotes CNS myelin repair independent of Fc function. Brain Pathology (Zurich, Switzerland). 13: 608-16. PMID 14655764 DOI: 10.1111/J.1750-3639.2003.Tb00489.X  0.325
2003 Nakane S, Zoecklein LJ, Gamez JD, Papke LM, Pavelko KD, Bureau JF, Brahic M, Pease LR, Rodriguez M. A 40-cM region on chromosome 14 plays a critical role in the development of virus persistence, demyelination, brain pathology and neurologic deficits in a murine viral model of multiple sclerosis. Brain Pathology (Zurich, Switzerland). 13: 519-33. PMID 14655757 DOI: 10.1111/J.1750-3639.2003.Tb00482.X  0.337
2003 Rodriguez M, Zoecklein LJ, Howe CL, Pavelko KD, Gamez JD, Nakane S, Papke LM. Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection. Journal of Virology. 77: 12252-65. PMID 14581562 DOI: 10.1128/Jvi.77.22.12252-12265.2003  0.362
2003 Zoecklein LJ, Pavelko KD, Gamez J, Papke L, McGavern DB, Ure DR, Njenga MK, Johnson AJ, Nakane S, Rodriguez M. Direct comparison of demyelinating disease induced by the Daniel's strain and BeAn strain of Theiler's murine encephalomyelitis virus. Brain Pathology (Zurich, Switzerland). 13: 291-308. PMID 12946019 DOI: 10.1111/J.1750-3639.2003.Tb00029.X  0.63
2003 Mendez-Fernandez YV, Johnson AJ, Rodriguez M, Pease LR. Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide. European Journal of Immunology. 33: 2501-10. PMID 12938226 DOI: 10.1002/Eji.200324007  0.347
2003 Lin X, Ma X, Rodriguez M, Feng X, Zoecklein L, Fu YX, Roos RP. Membrane lymphotoxin is required for resistance to Theiler's virus infection. International Immunology. 15: 955-62. PMID 12882833 DOI: 10.1093/Intimm/Mcg094  0.348
2003 Bieber AJ, Kerr S, Rodriguez M. Efficient central nervous system remyelination requires T cells. Annals of Neurology. 53: 680-4. PMID 12731006 DOI: 10.1002/Ana.10578  0.378
2003 Alley J, Khasabov S, Simone D, Beitz A, Rodriguez M, Njenga MK. More severe neurologic deficits in SJL/J male than female mice following Theiler's virus-induced CNS demyelination. Experimental Neurology. 180: 14-24. PMID 12668145 DOI: 10.1016/S0014-4886(02)00054-7  0.366
2003 Khare M, Rodriguez M, David CS. HLA class II transgenic mice authenticate restriction of myelin oligodendrocyte glycoprotein-specific immune response implicated in multiple sclerosis pathogenesis. International Immunology. 15: 535-46. PMID 12663683 DOI: 10.1093/Intimm/Dxg053  0.385
2003 Rodriguez M. A function of myelin is to protect axons from subsequent injury: Implications for deficits in multiple sclerosis Brain. 126: 751-752. PMID 12615635 DOI: 10.1093/Brain/Awg070  0.395
2003 Paz Soldán MM, Warrington AE, Bieber AJ, Ciric B, Van Keulen V, Pease LR, Rodriguez M. Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Molecular and Cellular Neurosciences. 22: 14-24. PMID 12595235 DOI: 10.1016/S1044-7431(02)00018-0  0.317
2003 Drescher KM, Zoecklein LJ, Rodriguez M. ICAM-1 is crucial for protection from TMEV-induced neuronal damage but not demyelination. Journal of Neurovirology. 8: 452-8. PMID 12402172 DOI: 10.1080/13550280260422767  0.371
2003 Rodriguez M. Diagnosis and Management of Multiple Sclerosis Journal of Neuropathology & Experimental Neurology. 62: 590-590. DOI: 10.1093/Jnen/62.5.590  0.31
2002 Paz Soldan MM, Rodriguez M. Heterogeneity of pathogenesis in multiple sclerosis: implications for promotion of remyelination. The Journal of Infectious Diseases. S248-53. PMID 12424705 DOI: 10.1086/344283  0.391
2002 Ransohoff RM, Howe CL, Rodriguez M. Growth factor treatment of demyelinating disease: at last, a leap into the light. Trends in Immunology. 23: 512-6. PMID 12401395 DOI: 10.1016/S1471-4906(02)02321-9  0.363
2002 Mitsunaga Y, Ciric B, Van Keulen V, Warrington AE, Paz Soldan M, Bieber AJ, Rodriguez M, Pease LR. Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1325-7. PMID 12154009 DOI: 10.1096/Fj.01-0994Fje  0.352
2002 Lin X, Njenga MK, Johnson AJ, Pavelko KD, David CS, Pease LR, Rodriguez M. Transgenic expression of Theiler's murine encephalomyelitis virus genes in H-2(b) mice inhibits resistance to virus-induced demyelination. Journal of Virology. 76: 7799-811. PMID 12097592 DOI: 10.1128/Jvi.76.15.7799-7811.2002  0.386
2002 Ure DR, Rodriguez M. Polyreactive antibodies to glatiramer acetate promote myelin repair in murine model of demyelinating disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1260-2. PMID 12060672 DOI: 10.1096/Fj.01-1023Fje  0.383
2002 Scarisbrick IA, Blaber SI, Lucchinetti CF, Genain CP, Blaber M, Rodriguez M. Activity of a newly identified serine protease in CNS demyelination. Brain : a Journal of Neurology. 125: 1283-96. PMID 12023317 DOI: 10.1093/Brain/Awf142  0.399
2002 Bieber AJ, Warrington A, Asakura K, Ciric B, Kaveri SV, Pease LR, Rodriguez M. Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice. Glia. 37: 241-9. PMID 11857682 DOI: 10.1002/Glia.10033  0.394
2002 Murray PD, McGavern DB, Pease LR, Rodriguez M. Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits. European Journal of Immunology. 32: 606-15. PMID 11857334 DOI: 10.1002/1521-4141(200203)32:3<606::Aid-Immu606>3.0.Co;2-D  0.607
2002 Blaber SI, Scarisbrick IA, Bernett MJ, Dhanarajan P, Seavy MA, Jin Y, Schwartz MA, Rodriguez M, Blaber M. Enzymatic properties of rat myelencephalon-specific protease. Biochemistry. 41: 1165-73. PMID 11802715 DOI: 10.1021/Bi015781A  0.367
2002 Keegan M, Pineda AA, McClelland RL, Darby CH, Rodriguez M, Weinshenker BG. Plasma exchange for severe attacks of CNS demyelination: predictors of response. Neurology. 58: 143-6. PMID 11781423 DOI: 10.1212/Wnl.58.1.143  0.302
2001 Bieber AJ, Warrington A, Pease LR, Rodriguez M. Humoral autoimmunity as a mediator of CNS repair. Trends in Neurosciences. 24: S39-44. PMID 11881744 DOI: 10.1016/S0166-2236(00)01991-3  0.359
2001 Johnson AJ, Upshaw J, Pavelko KD, Rodriguez M, Pease LR. Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2760-2. PMID 11606479 DOI: 10.1096/Fj.01-0373Fje  0.371
2001 Warrington AE, Bieber AJ, Ciric B, Van Keulen V, Pease LR, Mitsunaga Y, Paz Soldan MM, Rodriguez M. Immunoglobulin-mediated CNS repair. The Journal of Allergy and Clinical Immunology. 108: S121-5. PMID 11586279 DOI: 10.1067/Mai.2001.118301  0.378
2001 Zhu G, Flies DB, Tamada K, Sun Y, Rodriguez M, Fu YX, Chen L. Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Ealpha)-transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 2671-6. PMID 11509610 DOI: 10.4049/Jimmunol.167.5.2671  0.333
2001 Murray PD, McGavern DB, Sathornsumetee S, Rodriguez M. Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis. Brain : a Journal of Neurology. 124: 1403-16. PMID 11408335 DOI: 10.1093/Brain/124.7.1403  0.662
2000 Noseworthy JH, O'Brien PC, Weinshenker BG, Weis JA, Petterson TM, Erickson BJ, Windebank AJ, Whisnant JP, Stolp-Smith KA, Harper CM, Low PA, Romme LJ, Johnson M, An KN, Rodriguez M. IV immunoglobulin does not reverse established weakness in MS. Neurology. 55: 1135-43. PMID 11071491 DOI: 10.1212/Wnl.55.8.1135  0.357
2000 Sathornsumetee S, McGavern DB, Ure DR, Rodriguez M. Quantitative ultrastructural analysis of a single spinal cord demyelinated lesion predicts total lesion load, axonal loss, and neurological dysfunction in a murine model of multiple sclerosis. The American Journal of Pathology. 157: 1365-76. PMID 11021839 DOI: 10.1016/S0002-9440(10)64650-0  0.63
2000 Rodriguez M, Roos RP, McGavern D, Zoecklein L, Pavelko K, Sang H, Lin X. The CD4-mediated immune response is critical in determining the outcome of infection using Theiler's viruses with VP1 capsid protein point mutations. Virology. 275: 9-19. PMID 11017783 DOI: 10.1006/Viro.2000.0493  0.625
2000 McGavern DB, Zoecklein L, Sathornsumetee S, Rodriguez M. Assessment of hindlimb gait as a powerful indicator of axonal loss in a murine model of progressive CNS demyelination. Brain Research. 877: 396-400. PMID 10986359 DOI: 10.1016/S0006-8993(00)02710-4  0.612
2000 Kimura K, Hunter SF, Thollander MS, Loftus EV, Melton LJ, O'Brien PC, Rodriguez M, Phillips SF. Concurrence of inflammatory bowel disease and multiple sclerosis. Mayo Clinic Proceedings. 75: 802-806. PMID 10943233 DOI: 10.4065/75.8.802  0.352
2000 Pavelko KD, Drescher KM, McGavern DB, David CS, Rodriguez M. HLA-DQ polymorphism influences progression of demyelination and neurologic deficits in a viral model of multiple sclerosis. Molecular and Cellular Neurosciences. 15: 495-509. PMID 10860577 DOI: 10.1006/Mcne.2000.0843  0.588
2000 Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Annals of Neurology. 47: 707-17. PMID 10852536 DOI: 10.1002/1531-8249(200006)47:6<707::Aid-Ana3>3.0.Co;2-Q  0.42
2000 Warrington AE, Asakura K, Bieber AJ, Ciric B, Van Keulen V, Kaveri SV, Kyle RA, Pease LR, Rodriguez M. Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 6820-5. PMID 10841576 DOI: 10.1073/Pnas.97.12.6820  0.397
2000 Scarisbrick IA, Asakura K, Blaber S, Blaber M, Isackson PJ, Bieto T, Rodriguez M, Windebank AJ. Preferential expression of myelencephalon-specific protease by oligodendrocytes of the adult rat spinal cord white matter. Glia. 30: 219-30. PMID 10756072 DOI: 10.1002/(Sici)1098-1136(200005)30:3<219::Aid-Glia2>3.0.Co;2-2  0.317
2000 Drescher KM, Murray PD, Lin X, Carlino JA, Rodriguez M. TGF-beta 2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 164: 3207-13. PMID 10706712 DOI: 10.4049/Jimmunol.164.6.3207  0.349
2000 Drescher KM, Johnston SL, Hogancamp W, Nabozny GH, David CS, Rimm IJ, Wettstein PJ, Rodriguez M. V(beta)8(+) T cells protect from demyelinating disease in a viral model of multiple sclerosis. International Immunology. 12: 271-80. PMID 10700462 DOI: 10.1093/Intimm/12.3.271  0.359
2000 Njenga MK, Coenen MJ, DeCuir N, Yeh HY, Rodriguez M. Short-term treatment with interferon-alpha/beta promotes remyelination, whereas long-term treatment aggravates demyelination in a murine model of multiple sclerosis. Journal of Neuroscience Research. 59: 661-70. PMID 10686594 DOI: 10.1002/(Sici)1097-4547(20000301)59:5<661::Aid-Jnr9>3.0.Co;2-E  0.367
2000 McGavern DB, Murray PD, Rivera-Quiñones C, Schmelzer JD, Low PA, Rodriguez M. Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis. Brain : a Journal of Neurology. 123: 519-31. PMID 10686175 DOI: 10.1093/Brain/123.3.519  0.628
2000 Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain : a Journal of Neurology. 2279-95. PMID 10581222 DOI: 10.1093/Brain/122.12.2279  0.361
1999 Weinshenker BG, O'Brien PC, Petterson TM, Noseworthy JH, Lucchinetti CF, Dodick DW, Pineda AA, Stevens LN, Rodriguez M. A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. Annals of Neurology. 46: 878-86. PMID 10589540 DOI: 10.1002/1531-8249(199912)46:6<878::Aid-Ana10>3.0.Co;2-Q  0.32
1999 Rodriguez M, Lucchinetti CF. Is apoptotic death of the oligodendrocyte a critical event in the pathogenesis of multiple sclerosis? Neurology. 53: 1615-6. PMID 10563600 DOI: 10.1212/Wnl.53.8.1615  0.37
1999 McGavern DB, Murray PD, Rodriguez M. Quantitation of spinal cord demyelination, remyelination, atrophy, and axonal loss in a model of progressive neurologic injury. Journal of Neuroscience Research. 58: 492-504. PMID 10533042 DOI: 10.1002/(Sici)1097-4547(19991115)58:4<492::Aid-Jnr3>3.0.Co;2-P  0.614
1999 McGavern DB, Zoecklein L, Drescher KM, Rodriguez M. Quantitative assessment of neurologic deficits in a chronic progressive murine model of CNS demyelination. Experimental Neurology. 158: 171-81. PMID 10448429 DOI: 10.1006/Exnr.1999.7082  0.627
1999 Johnson AJ, Njenga MK, Hansen MJ, Kuhns ST, Chen L, Rodriguez M, Pease LR. Prevalent class I-restricted T-cell response to the Theiler's virus epitope Db:VP2121-130 in the absence of endogenous CD4 help, tumor necrosis factor alpha, gamma interferon, perforin, or costimulation through CD28. Journal of Virology. 73: 3702-8. PMID 10196262 DOI: 10.1128/Jvi.73.5.3702-3708.1999  0.345
1999 Njenga MK, Murray PD, McGavern D, Lin X, Drescher KM, Rodriguez M. Absence of spontaneous central nervous system remyelination in class II-deficient mice infected with Theiler's virus. Journal of Neuropathology and Experimental Neurology. 58: 78-91. PMID 10068316 DOI: 10.1097/00005072-199901000-00009  0.636
1999 Drescher KM, Murray PD, David CS, Pease LR, Rodriguez M. CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system. Brain Pathology (Zurich, Switzerland). 9: 21-31. PMID 9989447 DOI: 10.1111/J.1750-3639.1999.Tb00206.X  0.387
1998 Renno T, Taupin V, Bourbonnière L, Verge G, Tran E, De Simone R, Krakowski M, Rodriguez M, Peterson A, Owens T. Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE. Molecular and Cellular Neurosciences. 12: 376-89. PMID 9888990 DOI: 10.1006/Mcne.1998.0725  0.411
1998 Lucchinetti CF, Brueck W, Rodriguez M, Lassmann H. Multiple sclerosis: lessons from neuropathology. Seminars in Neurology. 18: 337-349. PMID 9817538 DOI: 10.1055/S-2008-1040885  0.402
1998 Drescher KM, Rivera-Quinones C, Lucchinetti CF, Rodriguez M. Failure of treatment with Linomide or oral myelin tolerization to ameliorate demyelination in a viral model of multiple sclerosis. Journal of Neuroimmunology. 88: 111-9. PMID 9688332 DOI: 10.1016/S0165-5728(98)00095-2  0.438
1998 Drescher KM, Nguyen LT, Taneja V, Coenen MJ, Leibowitz JL, Strauss G, Hammerling GJ, David CS, Rodriguez M. Expression of the human histocompatibility leukocyte antigen DR3 transgene reduces the severity of demyelination in a murine model of multiple sclerosis. The Journal of Clinical Investigation. 101: 1765-74. PMID 9541508 DOI: 10.1172/Jci167  0.42
1998 Rivera-Quiñones C, McGavern D, Schmelzer JD, Hunter SF, Low PA, Rodriguez M. Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis. Nature Medicine. 4: 187-193. PMID 9461192 DOI: 10.1038/Nm0298-187  0.653
1998 Lin X, Sato S, Patick AK, Pease LR, Roos RP, Rodriguez M. Molecular characterization of a nondemyelinating variant of Daniel's strain of Theiler's virus isolated from a persistently infected glioma cell line. Journal of Virology. 72: 1262-9. PMID 9445026 DOI: 10.1128/Jvi.72.2.1262-1269.1998  0.341
1998 Drescher KM, Pease LR, Rodriguez M. Antiviral immune responses modulate the nature of central nervous system (CNS) disease in a murine model of multiple sclerosis. Immunological Reviews. 159: 177-93. PMID 9416511 DOI: 10.1111/J.1600-065X.1997.Tb01015.X  0.335
1998 Asakura K, Miller DJ, Pease LR, Rodriguez M. Targeting of IgMκ Antibodies to Oligodendrocytes Promotes CNS Remyelination The Journal of Neuroscience. 18: 7700-7708. DOI: 10.1523/Jneurosci.18-19-07700.1998  0.393
1998 Murray PD, McGavern DB, Lin X, Njenga MK, Leibowitz J, Pease LR, Rodriguez M. Perforin-Dependent Neurologic Injury in a Viral Model of Multiple Sclerosis The Journal of Neuroscience. 18: 7306-7314. DOI: 10.1523/Jneurosci.18-18-07306.1998  0.66
1998 Lucchinetti CF, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. PATTERNS OF MULTIPLE SCLEROSIS IMMUNOPATHOLOGY Journal of Neuropathology and Experimental Neurology. 57: 489. DOI: 10.1097/00005072-199805000-00089  0.316
1998 Murray PD, Lin X, Njenga MK, Leibowitz J, Pease LR, Rodriguez M. THE ROLE OF PERFORIN AND FAS-MEDAITED CYTOTOXIC EFFECTOR FUNCTION IN THE DEVELOPMENT OF DEMYELINATION AND NEUROLOGIC DEFICITS IN A VIRAL MODEL OF MULTIPLE SCLEROSIS Journal of Neuropathology and Experimental Neurology. 57: 488. DOI: 10.1097/00005072-199805000-00088  0.38
1998 Drescher K, Murray P, David C, Pease L, Rodriguez M. CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system Journal of Neuroimmunology. 90: 65. DOI: 10.1016/S0165-5728(98)91565-X  0.322
1998 McGavern D, Rodriguez M. A novel method for the quantification of spinal cord damage in a murine viral model of multiple sclerosis Journal of Neuroimmunology. 90: 58. DOI: 10.1016/S0165-5728(98)91528-4  0.558
1998 Rodriguez M, Asakura K, Pease L. The role of natural autoantibodies in myelin repair Journal of Neuroimmunology. 90: 9. DOI: 10.1016/S0165-5728(98)91249-8  0.327
1997 Hunter SF, Leavitt JA, Rodriguez M. Direct observation of myelination in vivo in the mature human central nervous system. A model for the behaviour of oligodendrocyte progenitors and their progeny. Brain : a Journal of Neurology. 120: 2071-82. PMID 9397022 DOI: 10.1093/Brain/120.11.2071  0.338
1997 Lucchinetti CF, Kiers L, O'Duffy A, Gomez MR, Cross S, Leavitt JA, O'Brien P, Rodriguez M. Risk factors for developing multiple sclerosis after childhood optic neuritis. Neurology. 49: 1413-8. PMID 9371931 DOI: 10.1212/Wnl.49.5.1413  0.323
1997 Njenga MK, Asakura K, Hunter SF, Wettstein P, Pease LR, Rodriguez M. The immune system preferentially clears Theiler's virus from the gray matter of the central nervous system. Journal of Virology. 71: 8592-601. PMID 9343217 DOI: 10.1128/Jvi.71.11.8592-8601.1997  0.414
1997 Lucchinetti CF, Kimmel DW, Pavelko K, Rodriguez M. 5-Fluorouracil and levamisole exacerbate demyelination in susceptible mice infected with Theiler's virus. Experimental Neurology. 147: 123-9. PMID 9294409 DOI: 10.1006/Exnr.1997.6598  0.382
1997 Lassmann H, Brück W, Lucchinetti C, Rodriguez M. Remyelination in multiple sclerosis. Multiple Sclerosis Journal. 3: 133-136. PMID 9291167 DOI: 10.1177/135245859700300213  0.387
1997 Lucchinetti CF, Noseworthy JH, Rodriguez M. Promotion of endogenous remyelination in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 3: 71-5. PMID 9291156 DOI: 10.1177/135245859700300202  0.416
1997 Horwitz MS, Evans CF, McGavern DB, Rodriguez M, Oldstone MB. Primary demyelination in transgenic mice expressing interferon-gamma. Nature Medicine. 3: 1037-41. PMID 9288735 DOI: 10.1038/Nm0997-1037  0.699
1997 Hunter SF, Miller DJ, Rodriguez M. Monoclonal remyelination-promoting natural autoantibody SCH 94.03: pharmacokinetics and in vivo targets within demyelinated spinal cord in a mouse model of multiple sclerosis. Journal of the Neurological Sciences. 150: 103-13. PMID 9268236 DOI: 10.1016/S0022-510X(97)00080-4  0.4
1997 Miller DJ, Bright JJ, Sriram S, Rodriguez M. Successful treatment of established relapsing experimental autoimmune encephalomyelitis in mice with a monoclonal natural autoantibody. Journal of Neuroimmunology. 75: 204-9. PMID 9143256 DOI: 10.1016/S0165-5728(97)00027-1  0.44
1997 Lin X, Pease LR, Rodriguez M. Differential generation of class I H-2D- versus H-2K-restricted cytotoxicity against a demyelinating virus following central nervous system infection. European Journal of Immunology. 27: 963-70. PMID 9130651 DOI: 10.1002/Eji.1830270424  0.334
1997 Taupin V, Renno T, Bourbonnière L, Peterson AC, Rodriguez M, Owens T. Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system. European Journal of Immunology. 27: 905-13. PMID 9130643 DOI: 10.1002/Eji.1830270416  0.359
1997 Lucchinetti CF, Brück W, Rodriguez M, Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis. Brain Pathology (Zurich, Switzerland). 6: 259-74. PMID 8864283 DOI: 10.1111/J.1750-3639.1996.Tb00854.X  0.397
1997 Lucchinetti CF, Rodriguez M. The Controversy Surrounding the Pathogenesis of the Multiple Sclerosis Lesion Mayo Clinic Proceedings. 72: 665-678. DOI: 10.4065/72.7.665  0.421
1996 Armon C, Swanson JW, McLean JM, Westbrook PR, Okazaki H, Kurtin PJ, Kalyan-Raman UP, Rodriguez M. Subacute encephalomyelitis presenting as stiff-person syndrome: clinical, polygraphic, and pathologic correlations. Movement Disorders : Official Journal of the Movement Disorder Society. 11: 701-9. PMID 8914097 DOI: 10.1002/Mds.870110616  0.311
1996 Miller DJ, Njenga MK, Parisi JE, Rodriguez M. Multi-organ reactivity of a monoclonal natural autoantibody that promotes remyelination in a mouse model of multiple sclerosis. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 44: 1005-11. PMID 8773566 DOI: 10.1177/44.9.8773566  0.404
1996 Asakura K, Pogulis RJ, Pease LR, Rodriguez M. A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens. Journal of Neuroimmunology. 65: 11-9. PMID 8642059 DOI: 10.1016/0165-5728(95)00175-1  0.321
1996 Rodriguez M, Miller DJ, Lennon VA. Immunoglobulins reactive with myelin basic protein promote CNS remyelination. Neurology. 46: 538-45. PMID 8614528 DOI: 10.1212/Wnl.46.2.538  0.434
1996 Lin X, Thiemann NR, Pease LR, Rodriguez M. VP1 and VP2 capsid proteins of Theiler's virus are targets of H-2D-restricted cytotoxic lymphocytes in the central nervous system of B10 mice. Virology. 214: 91-9. PMID 8525642 DOI: 10.1006/Viro.1995.9951  0.347
1995 Kimmel DW, Wijdicks EF, Rodriguez M. Multifocal inflammatory leukoencephalopathy associated with levamisole therapy. Neurology. 45: 374-6. PMID 7854541 DOI: 10.1212/Wnl.45.2.374  0.306
1995 Hunter SF, Rodriguez M. Multiple sclerosis: a unique immunopathological syndrome of the central nervous system. Springer Seminars in Immunopathology. 17: 89-105. PMID 7482229 DOI: 10.1007/Bf00194102  0.37
1995 Rodriguez M, Pavelko K, Coffman RL. Gamma interferon is critical for resistance to Theiler's virus-induced demyelination. Journal of Virology. 69: 7286-90. PMID 7474155 DOI: 10.1128/Jvi.69.11.7286-7290.1995  0.385
1995 Nienga HK, Pavelko K, Thiemann R, Baisch J, Leibowitz J, David C, Rodriguez M. Demyelination Can Be Induced In Class Ii Deficient Mice: 27 Journal of Neuropathology and Experimental Neurology. 54: 418. DOI: 10.1097/00005072-199505000-00043  0.313
1994 Iuliano BA, Schmelzer JD, Thiemann RL, Low PA, Rodriguez M. Motor and somatosensory evoked potentials in mice infected with Theiler's murine encephalomyelitis virus. Journal of the Neurological Sciences. 123: 186-94. PMID 8064313 DOI: 10.1016/0022-510X(94)90222-4  0.346
1994 Rodriguez M, Prayoonwiwat N, Howe C, Sanborn K. Proteolipid protein gene expression in demyelination and remyelination of the central nervous system: A model for multiple sclerosis Journal of Neuropathology and Experimental Neurology. 53: 136-143. PMID 7509847 DOI: 10.1097/00005072-199403000-00004  0.404
1993 Prayoonwiwat N, Rodriguez M. The Potential for Oligodendrocyte Proliferation During Demyelinating Disease Journal of Neuropathology and Experimental Neurology. 52: 55-63. PMID 8381162 DOI: 10.1097/00005072-199301000-00007  0.406
1993 Rodriguez M, Karnes WE, Bartleson JD, Pineda AA. Plasmapheresis in acute episodes of fulminant CNS inflammatory demyelination. Neurology. 43: 1100-4. PMID 8170550 DOI: 10.1212/Wnl.43.6.1100  0.327
1993 Miller DJ, Sanborn K, Katzman JA, Rodriguez M. MONOCLONAL ANTIBODIES STIMULATE REMYELINATION IN A VIRAL MODEL OF MULTIPLE SCLEROSIS Journal of Neuropathology and Experimental Neurology. 52: 312. DOI: 10.1097/00005072-199305000-00206  0.336
1992 Rodriguez M, Roos RP. Pathogenesis of early and late disease in mice infected with Theiler's virus, using intratypic recombinant GDVII/DA viruses. Journal of Virology. 66: 217-25. PMID 1727485 DOI: 10.1128/Jvi.66.1.217-225.1992  0.368
1992 Hook CC, Kimmel DW, Kvols LK, Scheithauer BW, Forsyth PA, Rubin J, Moertel CG, Rodriguez M. Multifocal inflammatory leukoencephalopathy with 5-fluorouracil and levamisole. Annals of Neurology. 31: 262-7. PMID 1637134 DOI: 10.1002/Ana.410310306  0.339
1992 Rodriguez M. Central nervous system demyelination and remyelination in multiple sclerosis and viral models of disease Journal of Neuroimmunology. 40: 255-263. PMID 1430155 DOI: 10.1016/0165-5728(92)90141-7  0.457
1991 Prayoonwiwat N, Pease LR, Rodriguez M. Human T-cell lymphotropic virus type I sequences detected by nested polymerase chain reactions are not associated with multiple sclerosis. Mayo Clinic Proceedings. 66: 665-80. PMID 2072754 DOI: 10.1016/S0025-6196(12)62078-3  0.324
1991 Rodriguez M, Lindsley MD, Pierce ML. Role of T cells in resistance to Theiler's virus infection. Microbial Pathogenesis. 11: 269-81. PMID 1687607 DOI: 10.1016/0882-4010(91)90031-5  0.386
1991 Rodriguez M, O'Fallon M, Kurland LT, Wynn DR. Epidemiology of MS Neurology. 41: 158-158. DOI: 10.1212/Wnl.41.1.158  0.317
1990 Rodriguez M, Kenny JJ, Thiemann RL, Woloschak GE. Theiler's virus-induced demyelination in mice immunosuppressed with anti-IgM and in mice expressing the xid gene Microbial Pathogenesis. 8: 23-35. PMID 2333032 DOI: 10.1016/0882-4010(90)90005-B  0.395
1990 Fu J, Rodriguez M, Roos RP. Strains from both Theiler's virus subgroups encode a determinant for demyelination. Journal of Virology. 64: 6345-8. PMID 2243399 DOI: 10.1128/Jvi.64.12.6345-6348.1990  0.34
1990 Patick AK, Pease LR, David CS, Rodriguez M. Major histocompatibility complex-conferred resistance to Theiler's virus-induced demyelinating disease is inherited as a dominant trait in B10 congenic mice. Journal of Virology. 64: 5570-6. PMID 2214025 DOI: 10.1128/Jvi.64.11.5570-5576.1990  0.352
1990 Patick AK, Oleszak EL, Leibowitz JL, Rodriguez M. Persistent infection of a glioma cell line generates a Theiler's virus variant which fails to induce demyelinating disease in SJL/J mice Journal of General Virology. 71: 2123-2132. PMID 2212994 DOI: 10.1099/0022-1317-71-9-2123  0.361
1989 Rodriguez M. Multiple sclerosis: Basic concepts and hypothesis Mayo Clinic Proceedings. 64: 570-576. PMID 2657238 DOI: 10.1016/S0025-6196(12)65563-3  0.406
1989 Woloschak GE, Krco CJ, Rodriguez M. Anti-mu treatment suppresses immunoglobulin light-chain gene expression and Peyer's patch development. Molecular Immunology. 26: 351-8. PMID 2497338 DOI: 10.1016/0161-5890(89)90124-7  0.311
1989 Carter JL, Rodriguez M. Immunosuppressive treatment of multiple sclerosis. Mayo Clinic Proceedings. 64: 664-9. PMID 2473360 DOI: 10.1016/S0025-6196(12)65345-2  0.347
1989 Pierce M, Rodriguez M. Erichrome Stain for Myelin on Osmicated Tissue Embedded in Glycol Methacrylate Plastic Journal of Histotechnology. 12: 35-36. DOI: 10.1179/His.1989.12.1.35  0.361
1989 Patick AK, Pease LR, David CS, Rodriguez M. RESISTANCE TO THEILERʼS MURINE ENCEPHALOMYELITIS VIRUS (TMEV)-INDUCED DEMYELINATION IS INHERITED AS A DOMINANT TRAIT IN BIO CONGENIC MICE Journal of Neuropathology and Experimental Neurology. 48: 323. DOI: 10.1097/00005072-198905000-00074  0.334
1988 Rodriguez M. Mechanisms of virus-induced demyelination and remyelination Annals of the New York Academy of Sciences. 540: 240-251. PMID 3061337 DOI: 10.1111/J.1749-6632.1988.Tb27066.X  0.402
1988 Rodriguez M, Siegel LM, Hovanec-Burns D, Bologa L, Graves MC. Theiler's virus-associated antigens on the surfaces of cultured glial cells. Virology. 166: 463-74. PMID 2845658 DOI: 10.1016/0042-6822(88)90517-X  0.369
1988 Oleszak EL, Leibowitz JL, Rodriguez M. Isolation and characterization of two plaque size variants of Theiler's murine encephalomyelitis virus (DA strain). The Journal of General Virology. 69: 2413-8. PMID 2842440 DOI: 10.1099/0022-1317-69-9-2413  0.353
1987 Woloschak GE, Rodriguez M, Krco CJ. Immunoglobulin gene expression in wasted mice. Advances in Experimental Medicine and Biology. 216: 23-30. PMID 3120493 DOI: 10.1007/978-1-4684-5344-7_4  0.301
1987 Rodriguez M, Quddus J. Effect of cyclosporin A, silica quartz dust, and protease inhibitors on virus-induced demyelination. Journal of Neuroimmunology. 13: 159-74. PMID 3023445 DOI: 10.1016/0165-5728(86)90062-7  0.384
1987 Rodriguez M, Lennon VA, Benveniste EN, Merrill JE. Remyelination by oligodendrocytes stimulated by antiserum to spinal cord. Journal of Neuropathology and Experimental Neurology. 46: 84-95. PMID 2432195 DOI: 10.1097/00005072-198701000-00008  0.388
1986 Rodriguez M, Lafuse WP, Leibowitz J, David CS. Partial suppression of Theiler's virus-induced demyelination in vivo by administration of monoclonal antibodies to immune-response gene products (Ia-antigens) Neurology. 36: 964-970. PMID 3487048 DOI: 10.1212/Wnl.36.7.964  0.39
1986 Rodriguez M, Powell HC. Dysglobulinemic neuropathy: absence of immunoglobulin within myelin sheaths. Annals of Neurology. 19: 204-6. PMID 3008638 DOI: 10.1002/Ana.410190221  0.339
1985 Rodriguez M. Virus-induced demyelination in mice: 'Dying back' of oligodendrocytes Mayo Clinic Proceedings. 60: 433-438. PMID 4040195 DOI: 10.1016/S0025-6196(12)60865-9  0.401
1985 Rodriguez M, Lennon VA. SERA OF MICE HYPERIMMUNIZED WITH MYELIN COMPONENTS PROMOTE CNS REMYELINATION IN CHRONIC THEILERʼS VIRUS ENCEPHALOMYELITIS Journal of Neuropathology and Experimental Neurology. 44: 318. DOI: 10.1097/00005072-198505000-00044  0.379
1984 Oldstone MB, Rodriguez M, Daughaday WH, Lampert PW. Viral perturbation of endocrine function: disordered cell function leads to disturbed homeostasis and disease. Nature. 307: 278-81. PMID 6694729 DOI: 10.1038/307278A0  0.487
1984 Powell HC, Rodriguez M, Hughes RA. Microangiopathy of vasa nervorum in dysglobulinemic neuropathy. Annals of Neurology. 15: 386-94. PMID 6331277 DOI: 10.1002/Ana.410150414  0.313
1984 Oldstone MBA, Southern P, Rodriguez M, Lampert P. Virus persists in β cells of islets of langerhans and is associated with chemical manifestations of diabetes Science. 224: 1440-1443. PMID 6203172 DOI: 10.1126/Science.6203172  0.306
1984 Lang W, Rodriguez M, Lennon VA, Lampert PW. Demyelination and remyelination in murine viral encephalomyelitis. Annals of the New York Academy of Sciences. 436: 98-102. PMID 6085230 DOI: 10.1111/J.1749-6632.1984.Tb14779.X  0.381
1984 Lang W, Wiley CA, Lennon VA, Rodriguez M, Lampert PW. 65 THEILERʼS MURINE ENCEPHALOMYELITIS VIRUS (TMEV) INDUCED DEMYELINATING DISEASE Journal of Neuropathology and Experimental Neurology. 43: 314. DOI: 10.1097/00005072-198405000-00074  0.36
1983 Rodriguez M, Leibowitz JL, Lampert PW. Persistent infection of oligodendrocytes in Theiler's virus-induced encephalomyelitis. Annals of Neurology. 13: 426-33. PMID 6340596 DOI: 10.1002/Ana.410130409  0.39
1983 Knobler RL, Rodriguez M, Lampert PW, Oldstone MB. Virologic models of chronic relapsing demyelinating disease. Acta Neuropathologica. Supplementum. 9: 31-7. PMID 6312726 DOI: 10.1007/978-3-642-69094-5_4  0.505
1983 Leibowitz JL, Rodriguez M. Antigenic variants are not selected during persistent infection with Theiler's virus Infection and Immunity. 41: 440-442. PMID 6190757 DOI: 10.1128/Iai.41.1.440-442.1983  0.312
1983 Lampert PW, Fujinami RS, Rodriguez M, Leibowitz JL, Lang W. 63 FURTHER STUDIES ON THE PATHOGENESIS OF THEILERʼS MURINE ENCEPHALOMYELITIS Journal of Neuropathology and Experimental Neurology. 42: 326. DOI: 10.1097/00005072-198305000-00070  0.362
1982 Oldstone MB, Sinha YN, Blount P, Tishon A, Rodriguez M, von Wedel R, Lampert PW. Virus-induced alterations in homeostasis: alteration in differentiated functions of infected cells in vivo. Science (New York, N.Y.). 218: 1125-7. PMID 7146898 DOI: 10.1126/Science.7146898  0.495
1982 Rodriguez M, Lampert P, Buchmeier M, Oldstone M. ULTRASTRUCTURAL LOCALIZATION OF VIRAL ANTIGEN IN MICE PERSISTENTLY INFECTED WITH LYMPHOCYTIC CHORIOMENINGITIS VIRUS (LCMV) Journal of Neuropathology and Experimental Neurology. 41: 366. DOI: 10.1097/00005072-198205000-00085  0.504
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