Year |
Citation |
Score |
2020 |
Chen X, Liu W, Wang L, Lin D, Nie L, He K, Guo Z, Zhu F, Feng W, Liu W, Yuan J, Yang X, Spencer P, Liu J. Diabetes mellitus is associated with elevated urinary pyrrole markers of γ-diketones known to cause axonal neuropathy. Bmj Open Diabetes Research & Care. 8. PMID 32912928 DOI: 10.1136/Bmjdrc-2020-001575 |
0.31 |
|
2020 |
Román GC, Spencer PS, Reis J, Buguet A, Faris MEA, Katrak SM, Láinez M, Medina MT, Meshram C, Mizusawa H, Öztürk S, Wasay M. The neurology of COVID-19 revisited: A proposal from the Environmental Neurology Specialty Group of the World Federation of Neurology to implement international neurological registries. Journal of the Neurological Sciences. 414: 116884. PMID 32464367 DOI: 10.1016/J.Jns.2020.116884 |
0.303 |
|
2020 |
Spencer PS. Neuroprotein Targets of γ-Diketone Metabolites of Aliphatic and Aromatic Solvents That Induce Central-Peripheral Axonopathy. Toxicologic Pathology. 192623320910960. PMID 32162603 DOI: 10.1177/0192623320910960 |
0.335 |
|
2019 |
Spencer PS. Hypothesis: Etiologic and Molecular Mechanistic Leads for Sporadic Neurodegenerative Diseases Based on Experience With Western Pacific ALS/PDC. Frontiers in Neurology. 10: 754. PMID 31417480 DOI: 10.3389/Fneur.2019.00754 |
0.312 |
|
2019 |
Giménez-Roldán S, Morales-Asín F, Ferrer I, Spencer PS. Historical setting and neuropathology of lathyrism: Insights from the neglected 1944 report by Oliveras de la Riva. Journal of the History of the Neurosciences. 1-26. PMID 31268820 DOI: 10.1080/0964704X.2019.1600357 |
0.307 |
|
2016 |
Spencer PS, Palmer VS, Kisby GE. Seeking environmental causes of neurodegenerative disease and envisioning primary prevention. Neurotoxicology. PMID 27050202 DOI: 10.1016/J.Neuro.2016.03.017 |
0.316 |
|
2012 |
Spencer PS, Fry RC, Palmer VS, Kisby GE. Western Pacific ALS-PDC: a prototypical neurodegenerative disorder linked to DNA damage and aberrant proteogenesis? Frontiers in Neurology. 3: 180. PMID 23267344 DOI: 10.3389/Fneur.2012.00180 |
0.322 |
|
2008 |
Tshala-Katumbay D, Monterroso V, Kayton R, Lasarev M, Sabri M, Spencer P. Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 105: 134-41. PMID 18502740 DOI: 10.1093/Toxsci/Kfn103 |
0.351 |
|
2008 |
Sabri MI, Hashemi S, Kim MS, Spencer PS. Aromatic hydrocarbon 1,2-diacetylbenzene cross-links neurofilament and other proteins Journal of Neurochemistry. 81: 101-105. DOI: 10.1046/J.1471-4159.81.S1.40_9.X |
0.331 |
|
2007 |
Tshala-Katumbay DD, Spencer PS. Chapter 18 Toxic disorders of the upper motor neuron system. Handbook of Clinical Neurology. 82: 353-72. PMID 18808903 DOI: 10.1016/S0072-9752(07)80021-2 |
0.317 |
|
2007 |
Sabri MI, Hashemi SB, Lasarev MR, Spencer PS. Axonopathy-inducing 1,2-diacetylbenzene forms adducts with motor and cytoskeletal proteins required for axonal transport. Neurochemical Research. 32: 2152-9. PMID 17577667 DOI: 10.1007/S11064-007-9392-Z |
0.324 |
|
2006 |
Tshala-Katumbay DD, Palmer VS, Lasarev MR, Kayton RJ, Sabri MI, Spencer PS. Monocyclic and dicyclic hydrocarbons: structural requirements for proximal giant axonopathy. Acta Neuropathologica. 112: 317-24. PMID 16874529 DOI: 10.1007/S00401-006-0106-4 |
0.311 |
|
2005 |
Tshala-Katumbay DD, Palmer VS, Kayton RJ, Sabri MI, Spencer PS. A new murine model of giant proximal axonopathy. Acta Neuropathologica. 109: 405-10. PMID 15759132 DOI: 10.1007/S00401-005-0982-Z |
0.344 |
|
2004 |
Trimpin S, Mixon AE, Stapels MD, Kim MY, Spencer PS, Deinzer ML. Identification of endogenous phosphorylation sites of bovine medium and low molecular weight neurofilament proteins by tandem mass spectrometry. Biochemistry. 43: 2091-105. PMID 14967049 DOI: 10.1021/Bi030196Q |
0.653 |
|
2002 |
Sabri MI, Spencer PS. How does acrylamide perturb axon transport and induce nerve fiber degeneration? Commentary on forum position paper. Neurotoxicology. 23: 259-63; discussion 2. PMID 12224766 DOI: 10.1016/S0161-813X(02)00023-2 |
0.308 |
|
2002 |
Spencer PS, Kim MS, Sabri MI. Aromatic as well as aliphatic hydrocarbon solvent axonopathy. International Journal of Hygiene and Environmental Health. 205: 131-6. PMID 12018006 DOI: 10.1078/1438-4639-00138 |
0.332 |
|
2001 |
Kim MS, Sabri MI, Miller VH, Kayton RJ, Dixon DA, Spencer PS. 1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy. Toxicology and Applied Pharmacology. 177: 121-31. PMID 11740911 DOI: 10.1006/Taap.2001.9301 |
0.327 |
|
1999 |
Tor-Agbidye J, Palmer VS, Lasarev MR, Craig AM, Blythe LL, Sabri MI, Spencer PS. Bioactivation of cyanide to cyanate in sulfur amino acid deficiency: relevance to neurological disease in humans subsisting on cassava. Toxicological Sciences : An Official Journal of the Society of Toxicology. 50: 228-35. PMID 10478859 DOI: 10.1093/Toxsci/50.2.228 |
0.313 |
|
1999 |
Spencer PS. Food toxins, ampa receptors, and motor neuron diseases. Drug Metabolism Reviews. 31: 561-87. PMID 10461541 DOI: 10.1081/Dmr-100101936 |
0.331 |
|
1996 |
Ludolph AC, Spencer PS. Toxic models of upper motor neuron disease. Journal of the Neurological Sciences. 139: 53-9. PMID 8899659 DOI: 10.1016/0022-510X(96)00122-0 |
0.332 |
|
1991 |
Spencer PS, Kisby GE, Ludolph AC. Slow toxins, biologic markers, and long-latency neurodegenerative disease in the western Pacific region. Neurology. 41: 62-6; discussion 66-. PMID 2041595 DOI: 10.1212/Wnl.41.5_Suppl_2.62 |
0.32 |
|
1991 |
Ludolph AC, He F, Spencer PS, Hammerstad J, Sabri M. 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 18: 492-8. PMID 1782616 DOI: 10.1017/S0317167100032212 |
0.324 |
|
1990 |
Sabri MI, Spencer PS. Acrylamide impairs fast and slow axonal transport in rat optic system. Neurochemical Research. 15: 603-8. PMID 1699140 DOI: 10.1007/Bf00973750 |
0.309 |
|
1989 |
Schaumburg HH, Arezzo JC, Spencer PS. Delayed onset of distal axonal neuropathy in primates after prolonged low-level administration of a neurotoxin. Annals of Neurology. 26: 576-9. PMID 2817831 DOI: 10.1002/Ana.410260413 |
0.343 |
|
1989 |
Sabri MI, Dairman W, Fenton M, Juhasz L, Ng T, Spencer PS. Effect of exogenous pyruvate on acrylamide neuropathy in rats. Brain Research. 483: 1-11. PMID 2706498 DOI: 10.1016/0006-8993(89)90028-0 |
0.332 |
|
1989 |
Moretto A, Lotti M, Spencer PS. In vivo and in vitro regional differential sensitivity of neuropathy target esterase to di-n-butyl-2,2-dichlorovinyl phosphate. Archives of Toxicology. 63: 469-73. PMID 2619560 DOI: 10.1007/Bf00316450 |
0.347 |
|
1988 |
Ludolph AC, Hugon J, Román GC, Spencer PS, Schoenberg BS. A clinical neurophysiologic study of tropical spastic paraparesis. Muscle & Nerve. 11: 392-7. PMID 3398885 DOI: 10.1002/Mus.880110417 |
0.316 |
|
1988 |
Soiefer AI, Moretto A, Spencer PS, Sabri MI. Axotomy-induced ornithine decarboxylase activity in the mouse dorsal root ganglion is inhibited by the vinca alkaloids. Neurochemical Research. 13: 1169-73. PMID 2467222 DOI: 10.1007/Bf00971635 |
0.344 |
|
1988 |
Oaklander AL, Spencer PS. Cold blockade of axonal transport activates premitotic activity of Schwann cells and wallerian degeneration. Journal of Neurochemistry. 50: 490-6. PMID 2447241 DOI: 10.1111/J.1471-4159.1988.Tb02938.X |
0.337 |
|
1987 |
Spencer PS, Nunn PB, Hugon J, Ludolph AC, Ross SM, Roy DN, Robertson RC. Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin. Science (New York, N.Y.). 237: 517-22. PMID 3603037 DOI: 10.1126/Science.3603037 |
0.331 |
|
1987 |
Oaklander AL, Miller MS, Spencer PS. Early changes in degenerating mouse sciatic nerve are associated with endothelial cells. Brain Research. 419: 39-45. PMID 2445427 DOI: 10.1016/0006-8993(87)90566-X |
0.311 |
|
1987 |
Moretto A, Lotti M, Sabri MI, Spencer PS. Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy. Journal of Neurochemistry. 49: 1515-22. PMID 2444671 DOI: 10.1111/J.1471-4159.1987.Tb01022.X |
0.33 |
|
1987 |
Oaklander AL, Miller MS, Spencer PS. Rapid anterograde spread of premitotic activity along degenerating cat sciatic nerve. Journal of Neurochemistry. 48: 111-4. PMID 2432171 DOI: 10.1111/J.1471-4159.1987.Tb13134.X |
0.342 |
|
1986 |
Politis MJ, Spencer PS. Regeneration of rat optic axons into peripheral nerve grafts. Experimental Neurology. 91: 52-9. PMID 3940879 DOI: 10.1016/0014-4886(86)90025-7 |
0.326 |
|
1986 |
Pellegrino RG, Politis MJ, Ritchie JM, Spencer PS. Events in degenerating cat peripheral nerve: induction of Schwann cell S phase and its relation to nerve fibre degeneration. Journal of Neurocytology. 15: 17-28. PMID 3086507 DOI: 10.1007/Bf02057901 |
0.343 |
|
1986 |
Calne DB, Mcgeer E, Eisen A, Spencer P. Alzheimer'S Disease, Parkinson'S Disease, And Motoneurone Disease: Abiotropic Interaction Between Ageing And Environment? The Lancet. 328: 1067-1070. PMID 2877227 DOI: 10.1016/S0140-6736(86)90469-1 |
0.302 |
|
1985 |
Soiefer AI, Miller MS, Sabri MI, Spencer PS. The separation and identification of enolase isozymes of brain and sciatic nerve by high-pressure liquid anion-exchange chromatography. Brain Research. 342: 196-9. PMID 4041815 DOI: 10.1016/0006-8993(85)91375-7 |
0.31 |
|
1985 |
Ross SM, Sabri MI, Spencer PS. Action of acrylamide on selected enzymes of energy metabolism in denervated cat peripheral nerves. Brain Research. 340: 189-91. PMID 4027645 DOI: 10.1016/0006-8993(85)90793-0 |
0.304 |
|
1985 |
Spencer PS, Beaubernard CM, Bischoff-Fenton MC, Kurt TL. Clinical and experimental neurotoxicity of 2-t-butylazo-2-hydroxy-5-methylhexane. Annals of Neurology. 17: 28-32. PMID 3985582 DOI: 10.1002/Ana.410170108 |
0.309 |
|
1985 |
Pellegrino RG, Spencer PS. Schwann cell mitosis in response to regenerating peripheral axons in vivo. Brain Research. 341: 16-25. PMID 3929995 DOI: 10.1016/0006-8993(85)91467-2 |
0.341 |
|
1985 |
Miller MS, Spencer PS. The mechanisms of acrylamide axonopathy. Annual Review of Pharmacology and Toxicology. 25: 643-66. PMID 2408560 DOI: 10.1146/Annurev.Pa.25.040185.003235 |
0.367 |
|
1984 |
Zagoren JC, Seelig M, Bornstein MB, Spencer PS. The evolution of cellular degeneration in dorsal root ganglia exposed to doxorubicin in tissue culture. Journal of Neuropathology and Experimental Neurology. 43: 384-94. PMID 6737008 DOI: 10.1097/00005072-198407000-00004 |
0.313 |
|
1984 |
Spencer PS, Bischoff-Fenton MC, Moreno OM, Opdyke DL, Ford RA. Neurotoxic properties of musk ambrette. Toxicology and Applied Pharmacology. 75: 571-5. PMID 6474483 DOI: 10.1016/0041-008X(84)90194-7 |
0.33 |
|
1984 |
Schwab BW, Arezzo JC, Paldino AM, Flohe L, Matthiessen T, Spencer PS. Rabbit sural nerve responses to chronic treatment with thalidomide and supidimide. Muscle & Nerve. 7: 362-8. PMID 6330547 DOI: 10.1002/Mus.880070504 |
0.305 |
|
1983 |
Veronesi B, Peterson ER, Bornstein MB, Spencer PS. Ultrastructural studies of the dying-back process. VI. Examination of nerve fibers undergoing giant axonal degeneration in organotypic culture. Journal of Neuropathology and Experimental Neurology. 42: 153-65. PMID 6827287 DOI: 10.1097/00005072-198303000-00005 |
0.352 |
|
1983 |
Zagoren JC, Politis MJ, Spencer PS. Rapid reorganization of the axonal cytoskeleton induced by a gamma diketone. Brain Research. 270: 162-4. PMID 6683582 DOI: 10.1016/0006-8993(83)90807-7 |
0.329 |
|
1983 |
Politis MJ, Spencer PS. An in vivo assay of neurotropic activity. Brain Research. 278: 229-31. PMID 6640311 DOI: 10.1016/0006-8993(83)90242-1 |
0.316 |
|
1982 |
Arezzo JC, Schaumburg HH, Spencer PS. Structure and function of the somatosensory system: a neurotoxicological perspective. Environmental Health Perspectives. 44: 23-30. PMID 7084152 DOI: 10.1289/Ehp.824423 |
0.317 |
|
1982 |
Altenkirch H, Wagner HM, Stoltenburg G, Spencer PS. Nervous system responses of rats to subchronic inhalation of N-hexane and N-hexane + methyl-ethyl-ketone mixtures. Journal of the Neurological Sciences. 57: 209-19. PMID 6891717 DOI: 10.1016/0022-510X(82)90028-4 |
0.309 |
|
1982 |
Arezzo JC, Schaumburg HH, Vaughan HG, Spencer PS, Barna J. Hind limb somatosensory evoked potentials in the monkey: the effects of distal axonopathy. Annals of Neurology. 12: 24-32. PMID 6287913 DOI: 10.1002/Ana.410120105 |
0.309 |
|
1982 |
Politis MJ, Ederle K, Spencer PS. Tropism in nerve regeneration in vivo. Attraction of regenerating axons by diffusible factors derived from cells in distal nerve stumps of transected peripheral nerves. Brain Research. 253: 1-12. PMID 6185179 DOI: 10.1016/0006-8993(82)90667-9 |
0.343 |
|
1981 |
Grover-Johnson N, Spencer PS. Peripheral nerve abnormalities in aging rats. Journal of Neuropathology and Experimental Neurology. 40: 155-65. PMID 7463100 DOI: 10.1097/00005072-198103000-00007 |
0.332 |
|
1981 |
Sterman AB, Spencer PS. The pathogenesis of primary internodal demyelination produced by acetyl ethyl tetramethyl tetralin: evidence for preserved Schwann cell somal function. Journal of Neuropathology and Experimental Neurology. 40: 112-21. PMID 7463097 DOI: 10.1097/00005072-198103000-00004 |
0.354 |
|
1981 |
Politis MJ, Spencer PS. A method to separate spatially the temporal sequence of axon-Schwann cell interaction during nerve regeneration. Journal of Neurocytology. 10: 221-32. PMID 7310452 DOI: 10.1007/Bf01257968 |
0.327 |
|
1980 |
Politis MJ, Pellegrino RG, Spencer PS. Ultrastructural studies of the dying-back process. V. Axonal neurofilaments accumulate at sites of 2,5-hexanedione application: evidence for nerve fibre dysfunction in experimental hexacarbon neuropathy. Journal of Neurocytology. 9: 505-16. PMID 7192310 DOI: 10.1007/Bf01204839 |
0.356 |
|
1979 |
Weinberg EL, Spencer PS. Studies on the control of myelinogenesis. 3. Signalling of oligodendrocyte myelination by regenerating peripheral axons. Brain Research. 162: 273-9. PMID 761090 DOI: 10.1016/0006-8993(79)90289-0 |
0.335 |
|
1979 |
Spencer PS, Sterman AB, Horoupian DS, Foulds MM. Neurotoxic fragrance produces ceroid and myelin disease. Science (New York, N.Y.). 204: 633-5. PMID 432669 DOI: 10.1126/Science.432669 |
0.341 |
|
1979 |
Spencer PS, Weinberg HJ, Krygier-Brévart V, Zabrenetzky V. Anin vivo method to prepare normal Schwann cells free of axons and myelin. Brain Research. 165: 119-26. PMID 427575 DOI: 10.1016/0006-8993(79)90049-0 |
0.338 |
|
1979 |
Spencer PS, Sabri MI, Schaumburg HH, Moore CL. Does a defect of energy metabolism in the nerve fiber underlie axonal degeneration in polyneuropathies? Annals of Neurology. 5: 501-7. PMID 89830 DOI: 10.1002/Ana.410050602 |
0.344 |
|
1979 |
Schaumburg HH, Spencer PS. CLINICAL AND EXPERIMENTAL STUDIES OF DISTAL AXONOPATHY?A FREQUENT FORM OF BRAIN AND NERVE DAMAGE PRODUCED BY ENVIRONMENTAL CHEMICAL HAZARDS Annals of the New York Academy of Sciences. 329: 14-29. DOI: 10.1111/J.1749-6632.1979.Tb15331.X |
0.325 |
|
1978 |
Weinberg HJ, Spencer PS. The fate of Schwann cells isolated from axonal contact. Journal of Neurocytology. 7: 555-69. PMID 722316 DOI: 10.1007/Bf01260889 |
0.331 |
|
1978 |
Spencer PS, Schaumburg HH. Distal axonopathy: one common type of neurotoxic lesion. Environmental Health Perspectives. 26: 97-105. PMID 720323 DOI: 10.1289/Ehp.782697 |
0.332 |
|
1978 |
Spencer PS, Bischoff MC, Schaumburg HH. On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central--peripheral distal axonopathy. Toxicology and Applied Pharmacology. 44: 17-28. PMID 675688 DOI: 10.1016/0041-008X(78)90280-6 |
0.37 |
|
1978 |
Schaumburg HH, Spencer PS. Environmental hydrocarbons produce degeneration in cat hypothalamus and optic tract. Science (New York, N.Y.). 199: 199-200. PMID 413192 DOI: 10.1126/Science.413192 |
0.306 |
|
1977 |
Spencer PS, Schaumburg HH. Ultrastructural studies of the dying-back process. IV. Differential vulnerability of PNS and CNS fibers in experimental central-peripheral distal axonopathies. Journal of Neuropathology and Experimental Neurology. 36: 300-20. PMID 190358 DOI: 10.1097/00005072-197703000-00006 |
0.368 |
|
1977 |
Spencer PS, Schaumburg HH. Ultrastructural studies of the dying-back process. III. The evolution of experimental peripheral giant axonal degeneration. Journal of Neuropathology and Experimental Neurology. 36: 276-99. PMID 190357 DOI: 10.1097/00005072-197703000-00005 |
0.337 |
|
1976 |
Spencer PS, Schaumburg HH. Feline nervous system response to chronic intoxication with commercial grades of methyl n-butyl ketone, methyl isobutyl ketone, and methyl ethyl ketone. Toxicology and Applied Pharmacology. 37: 301-11. PMID 982453 DOI: 10.1016/0041-008X(76)90093-4 |
0.347 |
|
1976 |
Weinberg HJ, Spencer PS. Studies on the control of myelinogenesis. II. Evidence for neuronal regulation of myelin production. Brain Research. 113: 363-78. PMID 953741 DOI: 10.1016/0006-8993(76)90947-1 |
0.347 |
|
1976 |
Schaumburg HH, Spencer PS. Degeneration in central and peripheral nervous systems produced by pure n-hexane: an experimental study. Brain : a Journal of Neurology. 99: 183-92. PMID 186151 DOI: 10.1093/Brain/99.2.183 |
0.363 |
|
1976 |
DeBaecqne C, Raine CS, Spencer PS. COPPER BINDING AT PNS NODES OF RANVIER DORING DEMYELINATION AND REMYELINATION IN THE PERINEURIAL WINDOW Journal of Neuropathology and Experimental Neurology. 35: 321. DOI: 10.1111/J.1365-2990.1976.Tb00520.X |
0.303 |
|
1975 |
Weinberg HJ, Spencer PS. Studies on the control of myelinogenesis. I. Myelination of regenerating axons after entry into a foreign unmyelinated nerve. Journal of Neurocytology. 4: 395-418. PMID 1151437 DOI: 10.1007/Bf01261372 |
0.338 |
|
1975 |
Spencer PS, Schaumburg HH, Raleigh RL, Terhaar CJ. Nervous system degeneration produced by the industrial solvent methyl n-butyl ketone. Archives of Neurology. 32: 219-22. PMID 1124984 DOI: 10.1001/Archneur.1975.00490460035002 |
0.353 |
|
1975 |
Spencer PS, Schaumburg HH. Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone. Journal of Neurology, Neurosurgery, and Psychiatry. 38: 771-5. PMID 171344 DOI: 10.1136/Jnnp.38.8.771 |
0.32 |
|
1974 |
Schaumburg HH, Wiśniewski HM, Spencer PS. Ultrastructural studies of the dying-back process. I. Peripheral nerve terminal and axon degeneration in systemic acrylamide intoxication. Journal of Neuropathology and Experimental Neurology. 33: 260-84. PMID 4362700 DOI: 10.1097/00005072-197404000-00006 |
0.371 |
|
1974 |
Spencer PS, Thomas PK. Ultrastructural studies of the dying-back process. II. The sequestration and removal by Schwann cells and oligodendrocytes of organelles from normal and diseases axons. Journal of Neurocytology. 3: 763-83. PMID 4218866 DOI: 10.1007/Bf01097197 |
0.319 |
|
1973 |
Spencer PS, Raine CS, Wiśniewski H. Axon diameter and myelin thickness. Unusual relationships in dorsal root ganglia. The Anatomical Record. 176: 225-43. PMID 4197110 DOI: 10.1002/Ar.1091760209 |
0.319 |
|
1973 |
Spencer PS, Peterson ER, Madrid R, Raine CS. Effects of thallium salts on neuronal mitochondria in organotypic cord-ganglia-muscle combination cultures. The Journal of Cell Biology. 58: 79-95. PMID 4125375 DOI: 10.1083/Jcb.58.1.79 |
0.355 |
|
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