Yue Xiong - Publications

Affiliations: 
Biochemistry & Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biochemistry, Molecular Biology

178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen LL, Smith MD, Lv L, Nakagawa T, Li Z, Sun SC, Brown NG, Xiong Y, Xu YP. USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2. Science Advances. 6. PMID 32948596 DOI: 10.1126/Sciadv.Abc9730  0.335
2020 Xia YK, Zeng YR, Zhang ML, Liu P, Liu F, Zhang H, He CX, Sun YP, Zhang JY, Zhang C, Song L, Ding C, Tang YJ, Yang Z, Yang C, ... ... Xiong Y, et al. Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network. Protein & Cell. PMID 32683582 DOI: 10.1007/S13238-020-00754-2  0.38
2020 Cheng ZL, Zhang ML, Lin HP, Gao C, Song JB, Zheng Z, Li L, Zhang Y, Shen X, Zhang H, Huang Z, Zhan W, Zhang C, Hu X, Sun YP, ... ... Xiong Y, et al. The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming. Cell Reports. 32: 107877. PMID 32668244 DOI: 10.1016/J.Celrep.2020.107877  0.393
2019 Wang TX, Liang JY, Zhang C, Xiong Y, Guan KL, Yuan HX. The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis. Cell Death & Disease. 10: 755. PMID 31591388 DOI: 10.1038/S41419-019-1984-4  0.345
2019 Wang P, Yan F, Li Z, Yu Y, Parnell SE, Xiong Y. Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development. The Journal of Clinical Investigation. 130. PMID 31343991 DOI: 10.1172/Jci129107  0.309
2019 Li MT, Liang JY, Sun YP, Jin J, Xiong Y, Guan KL, Yuan HX. ELP3 acetyltransferase is phosphorylated and regulated by the oncogenic anaplastic lymphoma kinase (ALK). The Biochemical Journal. PMID 31341009 DOI: 10.1042/Bcj20190106  0.388
2019 Zhang M, Wu J, Sun R, Tao X, Wang X, Kang Q, Wang H, Zhang L, Liu P, Zhang J, Xia Y, Zhao Y, Yang Y, Xiong Y, Guan KL, et al. SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress. Plos One. 14: e0211796. PMID 30759120 DOI: 10.1371/Journal.Pone.0211796  0.306
2018 Chen LL, Lin HP, Zhou WJ, He CX, Zhang ZY, Cheng ZL, Song JB, Liu P, Chen XY, Xia YK, Chen XF, Sun RQ, Zhang JY, Sun YP, Song L, ... ... Xiong Y, et al. SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response. Cell Reports. 25: 1485-1500.e4. PMID 30404004 DOI: 10.1016/J.Celrep.2018.10.028  0.358
2018 Zhang C, Han XR, Yang X, Jiang B, Liu J, Xiong Y, Jin J. Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK). European Journal of Medicinal Chemistry. 151: 304-314. PMID 29627725 DOI: 10.1016/J.Ejmech.2018.03.071  0.336
2018 Ye D, Guan KL, Xiong Y. Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates. Trends in Cancer. 4: 151-165. PMID 29458964 DOI: 10.1016/J.Trecan.2017.12.005  0.302
2018 Li FL, Liu JP, Bao RX, Yan G, Feng X, Xu YP, Sun YP, Yan W, Ling ZQ, Xiong Y, Guan KL, Yuan HX. Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nature Communications. 9: 508. PMID 29410405 DOI: 10.1038/S41467-018-02950-5  0.364
2017 Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL. CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis. Molecular Cell. 68: 198-209.e6. PMID 28985504 DOI: 10.1016/J.Molcel.2017.09.008  0.301
2017 Mo Y, Lin R, Liu P, Tan M, Xiong Y, Guan KL, Yuan HX. SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes. The Febs Journal. PMID 28886238 DOI: 10.1111/Febs.14259  0.435
2017 Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, An W. Correction for Kim et al., "Vpr-Binding Protein Antagonizes p53-Mediated Transcription via Direct Interaction with H3 Tail". Molecular and Cellular Biology. 37. PMID 28710123 DOI: 10.1128/Mcb.00254-17  0.302
2017 Li Z, Xiong Y. Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53. Oncogene. PMID 28481879 DOI: 10.1038/Onc.2017.141  0.371
2017 Wang Z, Liu P, Zhou X, Wang T, Feng X, Sun YP, Xiong Y, Yuan HX, Guan KL. Endothelin promotes colorectal tumorigenesis by activating YAP/TAZ. Cancer Research. PMID 28249901 DOI: 10.1158/0008-5472.Can-16-3229  0.358
2016 Lin HP, Cheng ZL, He RY, Song L, Tian MX, Zhou L, S Groh B, Liu W, Ji MB, Ding C, Shi YH, Guan KL, Ye D, Xiong Y. Destabilization of fatty acid synthase by acetylation inhibits de novo lipogenesis and tumor cell growth. Cancer Research. PMID 27758890 DOI: 10.1158/0008-5472.Can-16-1597  0.369
2016 Murphy CM, Xu Y, Li F, Nio K, Reszka-Blanco N, Li X, Wu Y, Yu Y, Xiong Y, Su L. Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication. Cell Reports. 16: 2846-2854. PMID 27626656 DOI: 10.1016/J.Celrep.2016.08.026  0.339
2016 Zha Z, Han XR, Smith MD, Lei QY, Guan KL, Xiong Y. Hypertension-associated C825T polymorphism impairs the function of Gβ3 to target GRK2 ubiquitination. Cell Discovery. 2: 16005. PMID 27462452 DOI: 10.1038/Celldisc.2016.5  0.326
2016 Wang B, Liu J, Xiong Y, Yan Y, Sun B, Zhao Q, Duan L, Li P, Huang Y, Chen W. Soluble E-cadherin as a serum biomarker in patients with HBV-related liver diseases. Clinical Biochemistry. PMID 27452182 DOI: 10.1016/j.clinbiochem.2016.07.011  0.411
2016 Liu J, Wang D, Yuan R, Xiong Y, Liu M. Prognosis study of 908 patients with intracerebral hemorrhage in Chengdu, West of China. The International Journal of Neuroscience. 1-18. PMID 27451828 DOI: 10.1080/00207454.2016.1216414  0.384
2016 Liu J, Wang D, Li J, Xiong Y, Liu B, Wei C, Wu S, Lin J, Liu M. Increased Serum Alkaline Phosphatase as a Predictor of Symptomatic Hemorrhagic Transformation in Ischemic Stroke Patients with Atrial Fibrillation and/or Rheumatic Heart Disease. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. PMID 27425768 DOI: 10.1016/j.jstrokecerebrovasdis.2016.06.017  0.39
2016 Lyons SM, Cunningham CH, Welch JD, Groh B, Guo AY, Wei B, Whitfield ML, Xiong Y, Marzluff WF. A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues. Nucleic Acids Research. PMID 27402160 DOI: 10.1093/Nar/Gkw620  0.305
2016 Feng X, Liu P, Zhou X, Li MT, Li FL, Wang Z, Meng ZP, Sun YP, Yu Y, Xiong Y, Yuan HX, Guan KL. Thromboxane A2 Activates YAP/TAZ to Induce Vascular Smooth Muscle Cell Proliferation and Migration. The Journal of Biological Chemistry. PMID 27382053 DOI: 10.1074/Jbc.M116.739722  0.313
2016 Liu J, Wang D, Xiong Y, Liu B, Wei C, Ma Z, Wu B, Yuan R, Tang H, Liu M. A cohort study of relationship between serum calcium levels and cerebral microbleeds (CMBs) in ischemic stroke patients with AF and/or RHD. Medicine. 95: e4033. PMID 27368027 DOI: 10.1097/MD.0000000000004033  0.383
2016 Dong CF, Xiao J, Shan LB, Li HY, Xiong YJ, Yang GL, Liu J, Yao SM, Li SX, Le XH, Yuan J, Zhou BP, Tipoe GL, Liu YX. Combined acoustic radiation force impulse, aminotransferase to platelet ratio index and Forns index assessment for hepatic fibrosis grading in hepatitis B. World Journal of Hepatology. 8: 616-24. PMID 27190578 DOI: 10.4254/wjh.v8.i14.616  0.365
2016 Liu J, Wang D, Xiong Y, Yuan R, Tao W, Liu M. Low free triiodothyronine levels are related to symptomatic intracranial hemorrhage and poor functional outcomes after intravenous thrombolysis in acute ischemic stroke patients. Neurological Research. 1-5. PMID 27122235 DOI: 10.1080/01616412.2016.1178480  0.387
2016 Groh BS, Yan F, Smith MD, Yu Y, Chen X, Xiong Y. The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase. Embo Reports. PMID 27113764 DOI: 10.15252/Embr.201540500  0.363
2016 Sun R, Liu JP, Gao C, Xiong YY, Li M, Wang YP, Su YW, Lin M, Jiang AL, Xiong LF, Xie Y, Feng JP. Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population. Oncotarget. PMID 27105501 DOI: 10.18632/oncotarget.8865  0.402
2016 Gao SG, Zeng C, Liu JJ, Tian J, Cheng C, Zhang FJ, Xiong YL, Pan D, Xiao YB, Lei GH. Association between Wnt inhibitory factor-1 expression levels in articular cartilage and the disease severity of patients with osteoarthritis of the knee. Experimental and Therapeutic Medicine. 11: 1405-1409. PMID 27073457 DOI: 10.3892/etm.2016.3049  0.417
2016 Yu Q, Xiong Y, Liu J, Wang Q, Qiu Y, Wen D. Comparative proteomics analysis of apoptotic Spodoptera frugiperda cells during p35 knockout Autographa californica multiple nucleopolyhedrovirus infection. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 18: 21-29. PMID 26922645 DOI: 10.1016/j.cbd.2016.01.008  0.489
2016 Liu J, Wang D, Xiong Y, Liu B, Hao Z, Tao W, Liu M. Association of Elevated High Sensitivity Cardiac Troponin T(hs-cTnT) Levels with Hemorrhagic Transformation and 3-Month Mortality in Acute Ischemic Stroke Patients with Rheumatic Heart Disease in China. Plos One. 11: e0148444. PMID 26849554 DOI: 10.1371/journal.pone.0148444  0.383
2016 Yu Q, Xiong Y, Liu J, Wen D, Wu X, Yin H. Transcriptome Analysis of the SL221 Cells at the Early Stage during Spodoptera litura Nucleopolyhedrovirus Infection. Plos One. 11: e0147873. PMID 26840182 DOI: 10.1371/journal.pone.0147873  0.44
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Xiong Y, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.459
2016 Liu J, Wang D, Tan G, Yuan R, Xu M, Xiong Y, Liu M. Predicting the Outcomes of Acute Ischemic Stroke with Rheumatic Heart Disease: The Values of CHADS2, CHA2DS2-VASc, and HAS-BLED Scores. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. PMID 26774873 DOI: 10.1016/j.jstrokecerebrovasdis.2015.09.003  0.368
2016 Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, Whitmire JK, Xiong Y, Chen X, Wan YY. DCAF1 controls T-cell function via p53-dependent and -independent mechanisms. Nature Communications. 7: 10307. PMID 26728942 DOI: 10.1038/Ncomms10307  0.329
2016 Han XR, Zha Z, Yuan HX, Feng X, Xia YK, Lei QY, Guan KL, Xiong Y. KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation. Oncogene. PMID 26725323 DOI: 10.1038/Onc.2015.482  0.373
2015 Xiong Y, Qin Y, Liu L, Liu J, Jiang J, Liu P, Zhang LQ, Qi D, Li Z. The complete mitochondrial genome of the Placidochromis longimanus. Mitochondrial Dna. 1-2. PMID 26714218 DOI: 10.3109/19401736.2015.1122772  0.405
2015 Wang P, Wu J, Ma S, Zhang L, Yao J, Hoadley KA, Wilkerson MD, Perou CM, Guan KL, Ye D, Xiong Y. Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. Cell Reports. PMID 26686626 DOI: 10.1016/J.Celrep.2015.11.029  0.304
2015 Xu X, Wei X, Wang F, Liu J, Chen H, Xiong Y, Li M. Validation of a Simplified Chinese Version of the Pain Catastrophizing Scale and an Exploration of the Factors Predicting Catastrophizing in Pain Clinic Patients. Pain Physician. 18: E1059-E1072. PMID 26606019  0.366
2015 Yin DF, Zhou K, Liu JT, Hu L, Liu Y, Deng J, Wang SP, Xiong Y, Zhong W. Development and validation of an LC/MS/MS method for simultaneous determination of shionone and epi-friedelinol in rat plasma for pharmacokinetic study after oral administration of Aster tataricus extract. Biomedical Chromatography : Bmc. PMID 26581126 DOI: 10.1002/bmc.3658  0.369
2015 Tu H, Xiong Y, Huang H, Huang Y, Wan T, Deng T, Liu J. Individualized Treatment of Patients With Early-Stage Epithelial Ovarian Cancer After Incomplete Initial Surgery. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. PMID 26569056 DOI: 10.1097/IGC.0000000000000583  0.379
2015 Sun Y, Gu M, Zhu L, Liu J, Xiong Y, Wei Y, Li F. Gemcitabine upregulates ABCG2/BCRP and modulates the intracellular pharmacokinetic profiles of bioluminescence in pancreatic cancer cells. Anti-Cancer Drugs. PMID 26556627 DOI: 10.1097/CAD.0000000000000315  0.456
2015 Xiong YM, Zou XZ, Chen Q, Du XL, Liu JF. Relationship Between Gpx1 Pro198leu Polymorphism and Susceptibility of Kashin-Beck Disease. Value in Health : the Journal of the International Society For Pharmacoeconomics and Outcomes Research. 18: A638. PMID 26533582 DOI: 10.1016/j.jval.2015.09.2270  0.359
2015 Qiu N, Wei X, Fang W, Liu J, Xiong Y. [Dynamic changes and effect of primary cilia on adipogenesis during 3T3-L1 cell differentiation into adipocytes]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 31: 1473-8. PMID 26522354  0.386
2015 He F, Xiong Y, Liu J, Tong F, Yan D. Construction of Au-IDE/CFP10-ESAT6 aptamer/DNA-AuNPs MSPQC for rapid detection of Mycobacterium tuberculosis. Biosensors & Bioelectronics. 77: 799-804. PMID 26513286 DOI: 10.1016/j.bios.2015.10.054  0.395
2015 Liu J, Wang D, Lei C, Xiong Y, Yuan R, Hao Z, Tao W, Liu M. Etiology, clinical characteristics and prognosis of spontaneous intracerebral hemorrhage in children: A prospective cohort study in China. Journal of the Neurological Sciences. PMID 26433465 DOI: 10.1016/j.jns.2015.09.366  0.366
2015 Zhang J, Liu J, Zuo Y, Wang R, Xiong Y. Preparation of Thermo-Responsive Poly(ionic liquid)s-Based Nanogels via One-Step Cross-Linking Copolymerization. Molecules (Basel, Switzerland). 20: 17378-17392. PMID 26393567 DOI: 10.3390/molecules200917378  0.379
2015 Wang S, Jiang B, Zhang T, Liu L, Wang Y, Wang Y, Chen X, Lin H, Zhou L, Xia Y, Chen L, Yang C, Xiong Y, Ye D, Guan KL. Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. Plos Biology. 13: e1002243. PMID 26356530 DOI: 10.1371/Journal.Pbio.1002243  0.335
2015 Liu J, Wang D, Xiong Y, Liu B, Liu M. Anti-NMDAR Encephalitis of 11 Cases in China - Detailed Clinical, Laboratory and Imagiological Description. European Neurology. 74: 73-8. PMID 26277996 DOI: 10.1159/000435953  0.382
2015 Xiong Y, Liu J, Chen S, Zhou Q, Xu W, Tang C, Chen Y, Yang M, Lei X. Combination of external beam radiotherapy and Californium (Cf)-252 neutron intracavity brachytherapy is more effective in control of cervical squamous cell carcinoma than that of cervical adenocarcinoma. Medical Oncology (Northwood, London, England). 32: 670. PMID 26271794 DOI: 10.1007/s12032-015-0670-3  0.391
2015 Yu Q, Xiong Y, Gao H, Liu J, Chen Z, Wang Q, Wen D. Comparative proteomics analysis of Spodoptera frugiperda cells during Autographa californica multiple nucleopolyhedrovirus infection. Virology Journal. 12: 115. PMID 26239618 DOI: 10.1186/s12985-015-0346-9  0.461
2015 Zhang BL, Liu J, Lei Y, Xiong Y, Li H, Lin X, Yao RQ, Gao DS. An Epigenetic Mechanism of High Gdnf Transcription in Glioma Cells Revealed by Specific Sequence Methylation. Molecular Neurobiology. PMID 26232065 DOI: 10.1007/s12035-015-9365-1  0.455
2015 Lv XB, Liu CY, Wang Z, Sun YP, Xiong Y, Lei QY, Guan KL. PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction. Embo Reports. PMID 26116754 DOI: 10.15252/Embr.201439951  0.386
2015 Zha Z, Han X, Smith MD, Liu Y, Giguère PM, Kopanja D, Raychaudhuri P, Siderovski DP, Guan KL, Lei QY, Xiong Y. A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation. Molecular Cell. 58: 794-803. PMID 25982117 DOI: 10.1016/J.Molcel.2015.04.017  0.372
2015 Zhou X, Wang S, Wang Z, Feng X, Liu P, Lv XB, Li F, Yu FX, Sun Y, Yuan H, Zhu H, Xiong Y, Lei QY, Guan KL. Estrogen regulates Hippo signaling via GPER in breast cancer. The Journal of Clinical Investigation. 125: 2123-35. PMID 25893606 DOI: 10.1172/Jci79573  0.325
2015 Kong L, Li S, Huang M, Xiong Y, Zhang Q, Ye L, Liu J, Zhu X, Sun R, Guo Y. The roles of endoplasmic reticulum overload response induced by HCV and NS4B protein in human hepatocyte viability and virus replication. Plos One. 10: e0123190. PMID 25875501 DOI: 10.1371/journal.pone.0123190  0.407
2015 Ma S, Jiang B, Deng W, Gu ZK, Wu FZ, Li T, Xia Y, Yang H, Ye D, Xiong Y, Guan KL. D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. Oncotarget. 6: 8606-20. PMID 25825982 DOI: 10.18632/Oncotarget.3330  0.316
2015 Yang Y, Wei M, Xiong Y, Du X, Zhu S, Yang L, Zhang C, Liu JJ. Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap. Cell Research. 25: 496-516. PMID 25771685 DOI: 10.1038/Cr.2015.31  0.413
2015 Liu J, Ai H, Xiong Y, Li F, Wen Z, Liu W, Li T, Qin K, Wu J, Liu Y. Prevalence and correlation of infectious agents in hospitalized children with acute respiratory tract infections in Central China. Plos One. 10: e0119170. PMID 25751402 DOI: 10.1371/journal.pone.0119170  0.375
2015 Wang Y, Xiao M, Chen X, Chen L, Xu Y, Lv L, Wang P, Yang H, Ma S, Lin H, Jiao B, Ren R, Ye D, Guan KL, Xiong Y. WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation. Molecular Cell. 57: 662-73. PMID 25601757 DOI: 10.1016/J.Molcel.2014.12.023  0.36
2015 Yan J, Liu J, Xiong Y, Qin W, Tang C. Identification of the geographical origins of pomelos using multielement fingerprinting. Journal of Food Science. 80: C228-33. PMID 25597424 DOI: 10.1111/1750-3841.12746  0.381
2015 Nakagawa T, Lv L, Nakagawa M, Yu Y, Yu C, D'Alessio AC, Nakayama K, Fan HY, Chen X, Xiong Y. CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases. Molecular Cell. 57: 247-60. PMID 25557551 DOI: 10.1016/J.Molcel.2014.12.002  0.407
2015 Xiong Y, Zhou Z, Lin H, Lin M, Liu J, Niu G, Wang W, Jia Y, Leung TW, Liu D, Liu W, Fan X, Yin Q, Zhu W, Ma M, et al. The safety and long-term outcomes of angioplasty and stenting in symptomatic intracranial atherosclerotic stenosis. International Journal of Cardiology. 179: 23-4. PMID 25464398 DOI: 10.1016/J.Ijcard.2014.10.081  0.358
2015 Xiong Y, Sun Y, Ji B, Liu J, Wang G, Zheng Z. Systematic Review and Meta-Analysis of benefits and risks between normothermia and hypothermia during cardiopulmonary bypass in pediatric cardiac surgery. Paediatric Anaesthesia. 25: 135-42. PMID 25331483 DOI: 10.1111/pan.12560  0.362
2015 Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, Najafov A, Liu M, Li Y, Han X, Xiao J, Jin Z, Peng T, Gao Y, Cai Y, ... ... Xiong Y, et al. Author response: G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L Elife. DOI: 10.7554/Elife.06734.017  0.315
2014 Liu D, Liu JY, Chen Q, Xiong YM, Wang ZL. The Effect of Dietary Selenium Intake in The Gene Expression of P38, P65, and Caspase-3 in Fluorosis Patients. Value in Health : the Journal of the International Society For Pharmacoeconomics and Outcomes Research. 17: A771. PMID 27202841 DOI: 10.1016/j.jval.2014.08.318  0.422
2014 Zhang BL, Ni HB, Liu J, Lei Y, Li H, Xiong Y, Yao R, Yu ZQ, Gao DS. Egr-1 participates in abnormally high gdnf gene transcription mediated by histone hyperacetylation in glioma cells. Biochimica Et Biophysica Acta. 1839: 1161-9. PMID 25201174 DOI: 10.1016/j.bbagrm.2014.08.014  0.479
2014 Xiong Y, Liu J, Zhong F, Xu T, Cheng K. Identification of the free radical produced in the photolysis of 1,3,5-triamino-2,4,6-trinitrobenzene (TATB). The Journal of Physical Chemistry. A. 118: 6858-63. PMID 25081131 DOI: 10.1021/jp5029867  0.386
2014 Wang W, Liu J, Xiong Y, Zhu L, Zhou X. Analysis and classification of DNA-binding sites in single-stranded and double-stranded DNA-binding proteins using protein information. Iet Systems Biology. 8: 176-83. PMID 25075531 DOI: 10.1049/iet-syb.2013.0048  0.451
2014 Li Z, Pei XH, Yan J, Yan F, Cappell KM, Whitehurst AW, Xiong Y. CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity. Molecular Cell. 54: 805-19. PMID 24793696 DOI: 10.1016/J.Molcel.2014.03.046  0.352
2014 Yan J, Yan F, Li Z, Sinnott B, Cappell KM, Yu Y, Mo J, Duncan JA, Chen X, Cormier-Daire V, Whitehurst AW, Xiong Y. The 3M complex maintains microtubule and genome integrity. Molecular Cell. 54: 791-804. PMID 24793695 DOI: 10.1016/J.Molcel.2014.03.047  0.319
2014 Xu Y, Li F, Lv L, Li T, Zhou X, Deng CX, Guan KL, Lei QY, Xiong Y. Oxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutase. Cancer Research. 74: 3630-42. PMID 24786789 DOI: 10.1158/0008-5472.Can-13-3615  0.353
2014 Wang YP, Zhou LS, Zhao YZ, Wang SW, Chen LL, Liu LX, Ling ZQ, Hu FJ, Sun YP, Zhang JY, Yang C, Yang Y, Xiong Y, Guan KL, Ye D. Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress. The Embo Journal. 33: 1304-20. PMID 24769394 DOI: 10.1002/Embj.201387224  0.301
2014 Xiong Y, Liu W, Zhou Z, Lin H, Lin M, Liu J, Niu G, Wang W, Jia Y, Leung TW, Liu D, Fan X, Yin Q, Zhu W, Ma M, et al. Angioplasty and stenting in middle cerebral artery: results from multicenter China interventional stroke registry. International Journal of Cardiology. 174: 189-90. PMID 24746504 DOI: 10.1016/J.Ijcard.2014.03.181  0.392
2014 Li T, Liu M, Feng X, Wang Z, Das I, Xu Y, Zhou X, Sun Y, Guan KL, Xiong Y, Lei QY. Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal. The Journal of Biological Chemistry. 289: 3775-85. PMID 24362262 DOI: 10.1074/Jbc.M113.531640  0.304
2013 Yu M, Lizarzaburu M, Motani A, Fu Z, Du X, Liu JJ, Jiao X, Lai S, Fan P, Fu A, Liu Q, Murakoshi M, Nara F, Oda K, Okuyama R, ... ... Xiong Y, et al. Aminopyrazole-Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies. Acs Medicinal Chemistry Letters. 4: 829-34. PMID 24900757 DOI: 10.1021/ml4000854  0.396
2013 Kim K, Lee B, Kim J, Choi J, Kim JM, Xiong Y, Roeder RG, An W. Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation. Cell Reports. 5: 1690-703. PMID 24360965 DOI: 10.1016/J.Celrep.2013.11.038  0.307
2013 Lv L, Xu YP, Zhao D, Li FL, Wang W, Sasaki N, Jiang Y, Zhou X, Li TT, Guan KL, Lei QY, Xiong Y. Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization. Molecular Cell. 52: 340-52. PMID 24120661 DOI: 10.1016/J.Molcel.2013.09.004  0.378
2013 Kim TY, Jackson S, Xiong Y, Whitsett TG, Lobello JR, Weiss GJ, Tran NL, Bang YJ, Der CJ. CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 16868-73. PMID 24082123 DOI: 10.1073/Pnas.1306358110  0.393
2013 Lin R, Tao R, Gao X, Li T, Zhou X, Guan KL, Xiong Y, Lei QY. Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth. Molecular Cell. 51: 506-18. PMID 23932781 DOI: 10.1016/J.Molcel.2013.07.002  0.344
2013 Zhao D, Zou SW, Liu Y, Zhou X, Mo Y, Wang P, Xu YH, Dong B, Xiong Y, Lei QY, Guan KL. Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer. Cancer Cell. 23: 464-76. PMID 23523103 DOI: 10.1016/J.Ccr.2013.02.005  0.316
2013 Duronio RJ, Xiong Y. Signaling pathways that control cell proliferation. Cold Spring Harbor Perspectives in Biology. 5: a008904. PMID 23457258 DOI: 10.1101/Cshperspect.A008904  0.387
2013 Yuan HX, Xiong Y, Guan KL. Nutrient sensing, metabolism, and cell growth control. Molecular Cell. 49: 379-87. PMID 23395268 DOI: 10.1016/J.Molcel.2013.01.019  0.345
2013 Wang P, Dong Q, Zhang C, Kuan PF, Liu Y, Jeck WR, Andersen JB, Jiang W, Savich GL, Tan TX, Auman JT, Hoskins JM, Misher AD, Moser CD, Yourstone SM, ... ... Xiong Y, et al. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene. 32: 3091-100. PMID 22824796 DOI: 10.1038/Onc.2012.315  0.303
2013 Wang Y, Zhou L, Zhao Y, Wang S, Yang Y, Ye D, Xiong Y, Guan K. Abstract 5177: SIRT2 deacetylates and activates glucose-6-phosphate dehydrogenase (G6PD) to protect cells against oxidative stress. Cancer Research. 73: 5177-5177. DOI: 10.1158/1538-7445.Am2013-5177  0.337
2012 Huang W, Lv X, Liu C, Zha Z, Zhang H, Jiang Y, Xiong Y, Lei QY, Guan KL. The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition. The Journal of Biological Chemistry. 287: 26245-53. PMID 22692215 DOI: 10.1074/Jbc.M112.382036  0.403
2012 Xiao M, Yang H, Xu W, Ma S, Lin H, Zhu H, Liu L, Liu Y, Yang C, Xu Y, Zhao S, Ye D, Xiong Y, Guan KL. Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes & Development. 26: 1326-38. PMID 22677546 DOI: 10.1101/Gad.191056.112  0.319
2012 Zhang T, Wang S, Lin Y, Xu W, Ye D, Xiong Y, Zhao S, Guan KL. Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1. Cell Metabolism. 15: 75-87. PMID 22225877 DOI: 10.1016/J.Cmet.2011.12.005  0.352
2012 Kim K, Heo K, Choi J, Jackson S, Kim H, Xiong Y, An W. Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail. Molecular and Cellular Biology. 32: 783-96. PMID 22184063 DOI: 10.1128/Mcb.06037-11  0.394
2012 Kassmeier MD, Mondal K, Palmer VL, Raval P, Kumar S, Perry GA, Anderson DK, Ciborowski P, Jackson S, Xiong Y, Swanson PC. VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity. The Embo Journal. 31: 945-58. PMID 22157821 DOI: 10.1038/Emboj.2011.455  0.335
2012 Zhou X, Li TT, Feng X, Hsiang E, Xiong Y, Guan KL, Lei QY. Targeted polyubiquitylation of RASSF1C by the Mule and SCFβ-TrCP ligases in response to DNA damage. The Biochemical Journal. 441: 227-36. PMID 21910689 DOI: 10.1042/Bj20111500  0.433
2012 Wang P, Dong Q, Zhang C, Kuan P, Liu Y, Jeck WR, Andersen JB, Auman JT, Hoskins JM, Kim JW, Cibulskis K, Getz G, Hunt HV, Thorgeirsson SS, Roberts LR, ... ... Xiong Y, et al. Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas Cancer Research. 72: 1058-1058. DOI: 10.1158/1538-7445.Am2012-1058  0.33
2011 Nakagawa T, Xiong Y. Chromatin regulation by CRL4 E3 ubiquitin ligases: CUL4B targets WDR5 ubiquitylation in the nucleus. Cell Cycle (Georgetown, Tex.). 10: 4197-8. PMID 22107965 DOI: 10.4161/Cc.10.24.18407  0.314
2011 Nakagawa T, Xiong Y. X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression. Molecular Cell. 43: 381-91. PMID 21816345 DOI: 10.1016/J.Molcel.2011.05.033  0.351
2011 Jiang W, Wang S, Xiao M, Lin Y, Zhou L, Lei Q, Xiong Y, Guan KL, Zhao S. Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase. Molecular Cell. 43: 33-44. PMID 21726808 DOI: 10.1016/J.Molcel.2011.04.028  0.347
2011 Lv L, Li D, Zhao D, Lin R, Chu Y, Zhang H, Zha Z, Liu Y, Li Z, Xu Y, Wang G, Huang Y, Xiong Y, Guan KL, Lei QY. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Molecular Cell. 42: 719-30. PMID 21700219 DOI: 10.1016/J.Molcel.2011.04.025  0.354
2011 Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, ... ... Xiong Y, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nature Genetics. 43: 621-9. PMID 21642992 DOI: 10.1038/Ng.848  0.357
2011 Pei XH, Bai F, Li Z, Smith MD, Whitewolf G, Jin R, Xiong Y. Cytoplasmic CUL9/PARC ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis. Cancer Research. 71: 2969-77. PMID 21487039 DOI: 10.1158/0008-5472.Can-10-4300  0.362
2011 Zeng Y, Kotake Y, Pei XH, Smith MD, Xiong Y. p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb. Cancer Research. 71: 2781-92. PMID 21447739 DOI: 10.1158/0008-5472.Can-10-3483  0.357
2011 Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, ... ... Xiong Y, et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell. 19: 17-30. PMID 21251613 DOI: 10.1016/J.Ccr.2010.12.014  0.301
2011 Liu CY, Lv X, Li T, Xu Y, Zhou X, Zhao S, Xiong Y, Lei QY, Guan KL. PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ. The Journal of Biological Chemistry. 286: 5558-66. PMID 21189257 DOI: 10.1074/Jbc.M110.194019  0.402
2011 Kotake Y, Nakagawa T, Kitagawa K, Suzuki S, Liu N, Kitagawa M, Xiong Y. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene. 30: 1956-62. PMID 21151178 DOI: 10.1038/Onc.2010.568  0.317
2011 Guan KL, Xiong Y. Regulation of intermediary metabolism by protein acetylation. Trends in Biochemical Sciences. 36: 108-16. PMID 20934340 DOI: 10.1016/J.Tibs.2010.09.003  0.329
2010 Yan J, Xiong Y. Targeted ubiquitylation: the prey becomes predator. Molecular Cell. 40: 853-5. PMID 21172649 DOI: 10.1016/J.Molcel.2010.12.012  0.311
2010 Guan KL, Yu W, Lin Y, Xiong Y, Zhao S. Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides. Nature Protocols. 5: 1583-95. PMID 21085124 DOI: 10.1038/Nprot.2010.117  0.306
2010 Liu CY, Zha ZY, Zhou X, Zhang H, Huang W, Zhao D, Li T, Chan SW, Lim CJ, Hong W, Zhao S, Xiong Y, Lei QY, Guan KL. The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. The Journal of Biological Chemistry. 285: 37159-69. PMID 20858893 DOI: 10.1074/Jbc.M110.152942  0.38
2010 Lee HO, Zacharek SJ, Xiong Y, Duronio RJ. Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase. Molecular Biology of the Cell. 21: 3639-53. PMID 20826610 DOI: 10.1091/Mbc.E10-02-0130  0.753
2009 Jackson S, Xiong Y. CRL4s: the CUL4-RING E3 ubiquitin ligases. Trends in Biochemical Sciences. 34: 562-70. PMID 19818632 DOI: 10.1016/J.Tibs.2009.07.002  0.397
2009 Pei XH, Bai F, Smith MD, Usary J, Fan C, Pai SY, Ho IC, Perou CM, Xiong Y. CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis. Cancer Cell. 15: 389-401. PMID 19411068 DOI: 10.1016/J.Ccr.2009.03.004  0.337
2009 Jackson S, Xiong Y. Targeting protein ubiquitylation: DDB1 takes its RING off. Nature Cell Biology. 11: 379-81. PMID 19337321 DOI: 10.1038/Ncb0409-379  0.326
2009 Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of Biological Chemistry. 284: 13355-62. PMID 19324877 DOI: 10.1074/Jbc.M900843200  0.375
2009 Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. The Journal of Biological Chemistry. 284: 13669-75. PMID 19318352 DOI: 10.1074/Jbc.M901921200  0.331
2009 Kotake Y, Zeng Y, Xiong Y. DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation. Cancer Research. 69: 1809-14. PMID 19208841 DOI: 10.1158/0008-5472.Can-08-2739  0.383
2008 van Buuren N, Couturier B, Xiong Y, Barry M. Ectromelia virus encodes a novel family of F-box proteins that interact with the SCF complex. Journal of Virology. 82: 9917-27. PMID 18684824 DOI: 10.1128/Jvi.00953-08  0.342
2008 McCall CM, Miliani de Marval PL, Chastain PD, Jackson SC, He YJ, Kotake Y, Cook JG, Xiong Y. Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. Molecular and Cellular Biology. 28: 5621-33. PMID 18606781 DOI: 10.1128/Mcb.00232-08  0.706
2008 Zhang Y, Feng S, Chen F, Chen H, Wang J, McCall C, Xiong Y, Deng XW. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. The Plant Cell. 20: 1437-55. PMID 18552200 DOI: 10.1105/Tpc.108.058891  0.703
2008 Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y. WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase. Genes & Development. 22: 866-71. PMID 18381890 DOI: 10.1101/Gad.1624008  0.775
2008 Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Molecular and Cellular Biology. 28: 2426-36. PMID 18227151 DOI: 10.1128/Mcb.01874-07  0.389
2008 Lee JH, Terzaghi W, Gusmaroli G, Charron JB, Yoon HJ, Chen H, He YJ, Xiong Y, Deng XW. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. The Plant Cell. 20: 152-67. PMID 18223036 DOI: 10.1105/Tpc.107.055418  0.405
2008 Wilton BA, Campbell S, Van Buuren N, Garneau R, Furukawa M, Xiong Y, Barry M. Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases. Virology. 374: 82-99. PMID 18221766 DOI: 10.1016/J.Virol.2007.11.036  0.353
2007 Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. Genes & Development. 21: 49-54. PMID 17210787 DOI: 10.1101/Gad.1499407  0.398
2007 Bai F, Pei XH, Nishikawa T, Smith MD, Xiong Y. p18Ink4c, but not p27Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors. Molecular and Cellular Biology. 27: 1495-504. PMID 17145768 DOI: 10.1128/Mcb.01764-06  0.306
2006 He YJ, McCall CM, Hu J, Zeng Y, Xiong Y. DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Genes & Development. 20: 2949-54. PMID 17079684 DOI: 10.1101/Gad.1483206  0.699
2006 Shumway SD, Xiong Y. Twice primed: cyclin E is phosphorylated and isomerized before being ubiquitinated. Molecular Cell. 23: 149-50. PMID 16857579 DOI: 10.1016/J.Molcel.2006.07.002  0.364
2006 Bai F, Pei XH, Pandolfi PP, Xiong Y. p18 Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control. Molecular and Cellular Biology. 26: 4564-76. PMID 16738322 DOI: 10.1128/Mcb.00266-06  0.351
2006 Andrews P, He YJ, Xiong Y. Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function Oncogene. 25: 4534-4548. PMID 16547496 DOI: 10.1038/Sj.Onc.1209490  0.391
2006 Xiong Y, Kotake Y. No exit strategy? No problem: APC inhibits beta-catenin inside the nucleus. Genes & Development. 20: 637-42. PMID 16543216 DOI: 10.1101/Gad.1413206  0.376
2006 Hu J, Xiong Y. An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage. The Journal of Biological Chemistry. 281: 3753-6. PMID 16407242 DOI: 10.1074/Jbc.C500464200  0.349
2005 Zacharek SJ, Xiong Y, Shumway SD. Negative regulation of TSC1-TSC2 by mammalian D-type cyclins. Cancer Research. 65: 11354-60. PMID 16357142 DOI: 10.1158/0008-5472.Can-05-2236  0.755
2005 Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK. Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proceedings of the National Academy of Sciences of the United States of America. 102: 14659-64. PMID 16195383 DOI: 10.1073/Pnas.0503484102  0.366
2005 Furukawa M, Andrews PS, Xiong Y. Assays for RING family ubiquitin ligases. Methods in Molecular Biology (Clifton, N.J.). 301: 37-46. PMID 15917624 DOI: 10.1385/1-59259-895-1:037  0.381
2005 Pei XH, Xiong Y. Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues. Oncogene. 24: 2787-95. PMID 15838515 DOI: 10.1038/Sj.Onc.1208611  0.379
2005 McCall CM, Hu J, Xiong Y. Recruiting substrates to cullin 4-dependent ubiquitin ligases by DDB1. Cell Cycle (Georgetown, Tex.). 4: 27-9. PMID 15655366 DOI: 10.4161/Cc.4.1.1396  0.705
2005 Furukawa M, Xiong Y. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Molecular and Cellular Biology. 25: 162-71. PMID 15601839 DOI: 10.1128/Mcb.25.1.162-171.2005  0.431
2004 Goldenberg SJ, Cascio TC, Shumway SD, Garbutt KC, Liu J, Xiong Y, Zheng N. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases. Cell. 119: 517-28. PMID 15537541 DOI: 10.1016/J.Cell.2004.10.019  0.57
2004 Hu J, McCall CM, Ohta T, Xiong Y. Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. Nature Cell Biology. 6: 1003-9. PMID 15448697 DOI: 10.1038/Ncb1172  0.702
2004 Pei XH, Bai F, Tsutsui T, Kiyokawa H, Xiong Y. Genetic evidence for functional dependency of p18Ink4c on Cdk4. Molecular and Cellular Biology. 24: 6653-64. PMID 15254233 DOI: 10.1128/Mcb.24.15.6653-6664.2004  0.338
2003 Zhang Y, Wolf GW, Bhat K, Jin A, Allio T, Burkhart WA, Xiong Y. Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway. Molecular and Cellular Biology. 23: 8902-12. PMID 14612427 DOI: 10.1128/Mcb.23.23.8902-8912.2003  0.375
2003 Furukawa M, He YJ, Borchers C, Xiong Y. Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. Nature Cell Biology. 5: 1001-7. PMID 14528312 DOI: 10.1038/Ncb1056  0.417
2003 Tang ED, Wang CY, Xiong Y, Guan KL. A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 278: 37297-305. PMID 12867425 DOI: 10.1074/Jbc.M303389200  0.304
2003 Michel JJ, McCarville JF, Xiong Y. A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. The Journal of Biological Chemistry. 278: 22828-37. PMID 12676951 DOI: 10.1074/Jbc.M210358200  0.786
2003 Bai F, Pei XH, Godfrey VL, Xiong Y. Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis. Molecular and Cellular Biology. 23: 1269-77. PMID 12556487 DOI: 10.1128/Mcb.23.4.1269-1277.2003  0.33
2003 Shumway SD, Li Y, Xiong Y. 14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin. The Journal of Biological Chemistry. 278: 2089-92. PMID 12468542 DOI: 10.1074/Jbc.C200499200  0.326
2002 Liu J, Furukawa M, Matsumoto T, Xiong Y. NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Molecular Cell. 10: 1511-8. PMID 12504025 DOI: 10.1016/S1097-2765(02)00783-9  0.596
2002 Tourigny MR, Ursini-Siegel J, Lee H, Toellner KM, Cunningham AF, Franklin DS, Ely S, Chen M, Qin XF, Xiong Y, MacLennan IC, Chen-Kiang S. CDK inhibitor p18(INK4c) is required for the generation of functional plasma cells. Immunity. 17: 179-89. PMID 12196289 DOI: 10.1016/S1074-7613(02)00364-3  0.32
2002 Furukawa M, Ohta T, Xiong Y. Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. The Journal of Biological Chemistry. 277: 15758-65. PMID 11861641 DOI: 10.1074/Jbc.M108565200  0.37
2001 Kovalev GI, Franklin DS, Coffield VM, Xiong Y, Su L. An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 167: 3285-92. PMID 11544316 DOI: 10.4049/Jimmunol.167.6.3285  0.341
2001 Zhang Y, Xiong Y. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation Science. 292: 1910-1915. PMID 11397945 DOI: 10.1126/Science.1058637  0.356
2001 Yu P, Huang B, Shen M, Lau C, Chan E, Michel J, Xiong Y, Payan DG, Luo Y. p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues. Oncogene. 20: 484-9. PMID 11313979 DOI: 10.1038/Sj.Onc.1204113  0.728
2000 Furukawa M, Zhang Y, McCarville J, Ohta T, Xiong Y. The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Molecular and Cellular Biology. 20: 8185-97. PMID 11027288 DOI: 10.1128/Mcb.20.21.8185-8197.2000  0.78
2000 Franklin DS, Godfrey VL, O'Brien DA, Deng C, Xiong Y. Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity Molecular and Cellular Biology. 20: 6147-6158. PMID 10913196 DOI: 10.1128/Mcb.20.16.6147-6158.2000  0.342
1999 Ohta T, Michel JJ, Xiong Y. Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Oncogene. 18: 6758-66. PMID 10597284 DOI: 10.1038/Sj.Onc.1203115  0.761
1999 Zhang Y, Xiong Y. Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Molecular Cell. 3: 579-91. PMID 10360174 DOI: 10.1016/S1097-2765(00)80351-2  0.368
1999 Fuchs SY, Chen A, Xiong Y, Pan ZQ, Ronai Z. HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. Oncogene. 18: 2039-46. PMID 10321728 DOI: 10.1038/Sj.Onc.1202760  0.336
1999 Ohta T, Michel JJ, Schottelius AJ, Xiong Y. ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Molecular Cell. 3: 535-41. PMID 10230407 DOI: 10.1016/S1097-2765(00)80482-7  0.751
1998 Zariwala M, Liu J, Xiong Y. Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins. Oncogene. 17: 2787-98. PMID 9840943 DOI: 10.1038/Sj.Onc.1202505  0.353
1998 Franklin DS, Godfrey VL, Lee H, Kovalev GI, Schoonhoven R, Chen-Kiang S, Su L, Xiong Y. CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis. Genes & Development. 12: 2899-2911. PMID 9744866 DOI: 10.1101/Gad.12.18.2899  0.305
1998 Michel JJ, Xiong Y. Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 435-49. PMID 9663463  0.73
1998 Zhang Y, Xiong Y, Yarbrough WG. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell. 92: 725-34. PMID 9529249 DOI: 10.1016/S0092-8674(00)81401-4  0.396
1998 Phelps DE, Hsiao KM, Li Y, Hu N, Franklin DS, Westphal E, Lee EY, Xiong Y. Coupled transcriptional and translational control of cyclin-dependent kinase inhibitor p18INK4c expression during myogenesis. Molecular and Cellular Biology. 18: 2334-43. PMID 9528803 DOI: 10.1128/Mcb.18.4.2334  0.356
1998 Watanabe H, Pan ZQ, Schreiber-Agus N, DePinho RA, Hurwitz J, Xiong Y. Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57(KIP2) requires binding to proliferating cell nuclear antigen Proceedings of the National Academy of Sciences of the United States of America. 95: 1392-1397. PMID 9465025 DOI: 10.1073/Pnas.95.4.1392  0.395
1997 Phelps DE, Xiong Y. Assay For Activity Of Mammalian Cyclin D-Dependent Kinases Cdk4 And Cdk6 Methods in Enzymology. 283: 194-205. PMID 9251020 DOI: 10.1016/S0076-6879(97)83016-9  0.341
1996 Franklin DS, Xiong Y. Induction of p18INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation. Molecular Biology of the Cell. 7: 1587-1599. PMID 8898364 DOI: 10.1091/Mbc.7.10.1587  0.389
1996 Mayrose DR, Nichols MA, Xiong Y, Ke H. Purification and crystallization of cyclin‐dependent kinase inhibitor p21 Protein Science. 5: 1928-1930. PMID 8880918 DOI: 10.1002/Pro.5560050920  0.334
1996 Xiong Y, Kuppuswamy D, Li Y, Livanos EM, Hixon M, White A, Beach D, Tlsty TD. Alteration of cell cycle kinase complexes in human papillomavirus E6- and E7-expressing fibroblasts precedes neoplastic transformation. Journal of Virology. 70: 999-1008. PMID 8551641 DOI: 10.1128/Jvi.70.2.999-1008.1996  0.37
1996 Yee A, Wu L, Liu L, Kobayashi R, Xiong Y, Hall FL. Biochemical Characterization of the Human Cyclin-dependent Protein Kinase Activating Kinase IDENTIFICATION OF p35 AS A NOVEL REGULATORY SUBUNIT Journal of Biological Chemistry. 271: 471-477. PMID 8550604 DOI: 10.1074/Jbc.271.1.471  0.392
1995 Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y, Wang XF. Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 92: 5545-9. PMID 7777546 DOI: 10.1073/Pnas.92.12.5545  0.313
1995 Demetrick DJ, Matsumoto S, Hannon GJ, Okamoto K, Xiong Y, Zhang H, Beach DH. Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Cytogenetics and Cell Genetics. 69: 190-2. PMID 7698009 DOI: 10.1159/000133960  0.357
1995 Aprelikova O, Xiong Y, Liu ET. Both p16 and p21 Families of Cyclin-dependent Kinase (CDK) Inhibitors Block the Phosphorylation of Cyclin-dependent Kinases by the CDK-activating Kinase Journal of Biological Chemistry. 270: 18195-18197. PMID 7629134 DOI: 10.1074/Jbc.270.31.18195  0.314
1995 Li JM, Nichols MA, Chandrasekharan S, Xiong Y, Wang XF. Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site. The Journal of Biological Chemistry. 270: 26750-3. PMID 7592908 DOI: 10.1074/Jbc.270.45.26750  0.306
1994 Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature. 366: 701-4. PMID 8259214 DOI: 10.1038/366701A0  0.375
1994 Philipp A, Schneider A, Väsrik I, Finke K, Xiong Y, Beach D, Alitalo K, Eilers M. Repression of cyclin D1: a novel function of MYC. Molecular and Cellular Biology. 14: 4032-43. PMID 8196642 DOI: 10.1128/Mcb.14.6.4032  0.334
1994 Guan KL, Jenkins CW, Li Y, Nichols MA, Wu X, O'Keefe CL, Matera AG, Xiong Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes & Development. 8: 2939-52. PMID 8001816 DOI: 10.1101/Gad.8.24.2939  0.341
1993 Xiong Y, Zhang H, Beach D. Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation Genes and Development. 7: 1572-1583. PMID 8101826 DOI: 10.1101/Gad.7.8.1572  0.359
1993 Zhang H, Xiong Y, Beach D. Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes Molecular Biology of the Cell. 4: 897-906. PMID 7903056 DOI: 10.1091/Mbc.4.9.897  0.359
1992 Xiong Y, Zhang H, Beach D. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA Cell. 71: 505-514. PMID 1358458 DOI: 10.1016/0092-8674(92)90518-H  0.366
1991 Xiong Y, Connolly T, Futcher B, Beach D. Human D-type cyclin. Cell. 65: 691-9. PMID 1827756 DOI: 10.1016/0092-8674(91)90100-D  0.317
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