James A. Swenberg, DVM - Publications

Affiliations: 
Environmental Science and Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 

184 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Walker V, Fennell TR, Walker DM, Bauer MJ, Upton PB, Douglas GR, Swenberg JA. Analysis of DNA Adducts and Mutagenic Potency and Specificity in Rats Exposed to Acrylonitrile. Chemical Research in Toxicology. PMID 32529823 DOI: 10.1021/Acs.Chemrestox.0C00153  0.49
2019 Leng J, Liu CW, Hartwell HJ, Yu R, Lai Y, Bodnar WM, Lu K, Swenberg JA. Evaluation of inhaled low-dose formaldehyde-induced DNA adducts and DNA-protein cross-links by liquid chromatography-tandem mass spectrometry. Archives of Toxicology. PMID 30701286 DOI: 10.1007/S00204-019-02393-X  0.551
2018 Liu CW, Tian X, Hartwell HJ, Leng J, Chi L, Lu K, Swenberg JA. Accurate Measurement of Formaldehyde-Induced DNA-Protein Crosslinks by High-resolution Orbitrap Mass Spectrometry. Chemical Research in Toxicology. PMID 29651845 DOI: 10.1021/Acs.Chemrestox.8B00040  0.462
2017 De La Rosa VY, Asfaha J, Fasullo M, Loguinov A, Li P, Moore LE, Rothman N, Nakamura J, Swenberg J, Scelo G, Zhang L, Smith MT, Vulpe CD. High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28973557 DOI: 10.1093/Toxsci/Kfx159  0.42
2017 Edrissi B, Taghizadeh K, Moeller BC, Yu R, Kracko D, Doyle-Eisele M, Swenberg JA, Dedon PC. N(6)-Formyllysine as a biomarker of formaldehyde exposure: Formation and loss of N(6)-formyllysine in nasal epithelium in long-term, low-dose inhalation studies in rats. Chemical Research in Toxicology. PMID 28692800 DOI: 10.1021/Acs.Chemrestox.7B00075  0.458
2017 Klaus V, Bastek H, Damme K, Collins LB, Frötschl R, Benda N, Lutter D, Ellinger-Ziegelbauer H, Swenberg JA, Dietrich DR, Stemmer K. Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats. Archives of Toxicology. PMID 28349193 DOI: 10.1007/S00204-017-1953-6  0.457
2017 Gao L, Mutlu E, Collins LB, Walker NJ, Hartwell HJ, Olson JR, Sun W, Gold A, Ball LM, Swenberg JA. DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure. Chemical Research in Toxicology. PMID 28207250 DOI: 10.1021/Acs.Chemrestox.6B00368  0.69
2016 Tian X, Patel K, Ridpath JR, Chen Y, Zhou YH, Neo D, Clement J, Takata M, Takeda S, Sale J, Wright FA, Swenberg JA, Nakamura J. Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. Plos One. 11: e0167503. PMID 27907204 DOI: 10.1371/Journal.Pone.0167503  0.458
2016 Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Oncotarget. PMID 27486975 DOI: 10.18632/Oncotarget.10928  0.421
2016 Mutlu E, Gao L, Collins LB, Walker NJ, Hartwell HJ, Olson JR, Sun W, Gold A, Ball LM, Swenberg JA. Polychlorinated Biphenyls Induce Oxidative DNA Adducts in Female Sprague-Dawley Rats. Chemical Research in Toxicology. PMID 27436759 DOI: 10.1021/Acs.Chemrestox.6B00146  0.709
2016 Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, et al. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature. PMID 27027282 DOI: 10.1038/Nature17640  0.352
2016 Sharma V, Collins LB, Chen TH, Herr N, Takeda S, Sun W, Swenberg JA, Nakamura J. Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations. Oncotarget. PMID 27015367 DOI: 10.18632/Oncotarget.8298  0.44
2016 Lai Y, Yu R, Hartwell HJ, Moeller BC, Bodnar WM, Swenberg JA. Measurement of endogenous versus exogenous formaldehyde-induced DNA-protein crosslinks in animal tissues by stable isotope labeling and ultrasensitive mass spectrometry. Cancer Research. PMID 26984759 DOI: 10.1158/0008-5472.Can-15-2527  0.406
2015 Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ. Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen. Molecular Cell. PMID 26412304 DOI: 10.1016/J.Molcel.2015.08.020  0.436
2015 Leng S, Wu G, Collins LB, Thomas CL, Tellez CS, Jauregui AR, Picchi MA, Zhang X, Juri DE, Desai D, Amin SG, Crowell RE, Stidley CA, Liu Y, Swenberg JA, et al. Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung. Cancer Research. PMID 26183928 DOI: 10.1158/0008-5472.Can-15-0243  0.373
2015 Hashimoto K, Takeda S, Swenberg JA, Nakamura J. Incorporation of metabolic activation potentiates cyclophosphamide-induced DNA damage response in isogenic DT40 mutant cells. Mutagenesis. 30: 821-8. PMID 26085549 DOI: 10.1093/Mutage/Gev042  0.388
2015 Yu R, Lai Y, Hartwell HJ, Moeller BC, Doyle-Eisele M, Kracko D, Bodnar WM, Starr TB, Swenberg JA. Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage. Toxicological Sciences : An Official Journal of the Society of Toxicology. 146: 170-82. PMID 25904104 DOI: 10.1093/Toxsci/Kfv079  0.563
2014 Shibutani T, Ito S, Toda M, Kanao R, Collins LB, Shibata M, Urabe M, Koseki H, Masuda Y, Swenberg JA, Masutani C, Hanaoka F, Iwai S, Kuraoka I. Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication. Scientific Reports. 4: 5220. PMID 24910358 DOI: 10.1038/Srep05220  0.451
2014 Sangaraju D, Villalta PW, Wickramaratne S, Swenberg J, Tretyakova N. NanoLC/ESI+ HRMS3 quantitation of DNA adducts induced by 1,3-butadiene. Journal of the American Society For Mass Spectrometry. 25: 1124-35. PMID 24867429 DOI: 10.1007/S13361-014-0916-X  0.837
2014 Nakamura J, Mutlu E, Sharma V, Collins L, Bodnar W, Yu R, Lai Y, Moeller B, Lu K, Swenberg J. The endogenous exposome. Dna Repair. 19: 3-13. PMID 24767943 DOI: 10.1016/J.Dnarep.2014.03.031  0.488
2014 Sharma V, Collins LB, Clement JM, Zhang Z, Nakamura J, Swenberg JA. Molecular dosimetry of endogenous and exogenous O(6)-methyl-dG and N7-methyl-G adducts following low dose [D3]-methylnitrosourea exposures in cultured human cells. Chemical Research in Toxicology. 27: 480-2. PMID 24628573 DOI: 10.1021/Tx5000602  0.394
2014 Kotapati S, Sangaraju D, Esades A, Hallberg L, Walker VE, Swenberg JA, Tretyakova NY. Bis-butanediol-mercapturic acid (bis-BDMA) as a urinary biomarker of metabolic activation of butadiene to its ultimate carcinogenic species. Carcinogenesis. 35: 1371-8. PMID 24531806 DOI: 10.1093/Carcin/Bgu047  0.805
2014 Pottenger LH, Andrews LS, Bachman AN, Boogaard PJ, Cadet J, Embry MR, Farmer PB, Himmelstein MW, Jarabek AM, Martin EA, Mauthe RJ, Persaud R, Preston RJ, Schoeny R, Skare J, ... Swenberg JA, et al. An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride. Critical Reviews in Toxicology. 44: 348-91. PMID 24494825 DOI: 10.3109/10408444.2013.873768  0.408
2014 Lu K, Mahbub R, Cable PH, Ru H, Parry NM, Bodnar WM, Wishnok JS, Styblo M, Swenberg JA, Fox JG, Tannenbaum SR. Gut microbiome phenotypes driven by host genetics affect arsenic metabolism. Chemical Research in Toxicology. 27: 172-4. PMID 24490651 DOI: 10.1021/Tx400454Z  0.419
2014 Lu K, Abo RP, Schlieper KA, Graffam ME, Levine S, Wishnok JS, Swenberg JA, Tannenbaum SR, Fox JG. Arsenic exposure perturbs the gut microbiome and its metabolic profile in mice: an integrated metagenomics and metabolomics analysis. Environmental Health Perspectives. 122: 284-91. PMID 24413286 DOI: 10.1289/Ehp.1307429  0.528
2014 Tian X, Patel K, Ridpath JR, Swenberg JA, Nakamura J. Abstract 5363: Genotoxicity of trace level of hexavalent chromium existing in city water Cancer Research. 74: 5363-5363. DOI: 10.1158/1538-7445.Am2014-5363  0.326
2014 Sangaraju D, Villalta PW, Wickramaratne S, Swenberg J, Tretyakova N. Erratum to: NanoLC/ESI+ HRMS3 Quantitation of DNA Adducts Induced by 1,3-Butadiene Journal of the American Society For Mass Spectrometry. 25: 1674-1674. DOI: 10.1007/S13361-014-0943-7  0.837
2013 Lu K, Cable PH, Abo RP, Ru H, Graffam ME, Schlieper KA, Parry NM, Levine S, Bodnar WM, Wishnok JS, Styblo M, Swenberg JA, Fox JG, Tannenbaum SR. Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformation. Chemical Research in Toxicology. 26: 1893-903. PMID 24134150 DOI: 10.1021/Tx4002868  0.523
2013 Moeller BC, Recio L, Green A, Sun W, Wright FA, Bodnar WM, Swenberg JA. Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 1-12. PMID 23425604 DOI: 10.1093/Toxsci/Kft029  0.397
2013 Swenberg JA, Moeller BC, Lu K, Rager JE, Fry RC, Starr TB. Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment. Toxicologic Pathology. 41: 181-9. PMID 23160431 DOI: 10.1177/0192623312466459  0.428
2013 Donohoe D, Montgomery S, Collins L, Holley D, Godfrey V, Swenberg J, Bultman S. Abstract SY08-03: Metaboloepigenetic effects of microbial-produced butyrate in cancer prevention. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy08-03  0.318
2013 Nakamura J, Tian X, Swenberg J. Abstract LB-151: REV1 has critical roles in base excision repair intermediate-mediated transversion mutations but not for O6-methylguanine-initiated mutations in vertebrate cells. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-151  0.387
2013 Tian X, Swenberg J, Nakamura J. Abstract 1281: POLD3 is required for DNA damage response to endogenous and exogenous DNA damage in human cells. Cancer Research. 73: 1281-1281. DOI: 10.1158/1538-7445.Am2013-1281  0.477
2012 Nakamura J, Gul H, Tian X, Bultman SJ, Swenberg JA. Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system. Plos One. 7: e33563. PMID 22428069 DOI: 10.1371/Journal.Pone.0033563  0.331
2012 Sangaraju D, Goggin M, Walker V, Swenberg J, Tretyakova N. NanoHPLC-nanoESI(+)-MS/MS quantitation of bis-N7-guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene. Analytical Chemistry. 84: 1732-9. PMID 22220765 DOI: 10.1021/Ac203079C  0.836
2012 Mutlu E, Jeong YC, Collins LB, Ham AJ, Upton PB, Hatch G, Winsett D, Evansky P, Swenberg JA. A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-Oxoethyl)guanine in sprague-dawley rats. Chemical Research in Toxicology. 25: 391-9. PMID 22211352 DOI: 10.1021/Tx200447W  0.655
2012 Lu K, Gul H, Upton PB, Moeller BC, Swenberg JA. Formation of hydroxymethyl DNA adducts in rats orally exposed to stable isotope labeled methanol. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 28-38. PMID 22157354 DOI: 10.1093/Toxsci/Kfr328  0.531
2012 Lu K, Craft S, Nakamura J, Moeller BC, Swenberg JA. Use of LC-MS/MS and stable isotopes to differentiate hydroxymethyl and methyl DNA adducts from formaldehyde and nitrosodimethylamine. Chemical Research in Toxicology. 25: 664-75. PMID 22148432 DOI: 10.1021/Tx200426B  0.529
2012 Boysen G, Georgieva NI, Bordeerat NK, Sram RJ, Vacek P, Albertini RJ, Swenberg JA. Formation of 1,2:3,4-diepoxybutane-specific hemoglobin adducts in 1,3-butadiene exposed workers. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 30-40. PMID 22003190 DOI: 10.1093/Toxsci/Kfr272  0.8
2012 King CL, Ramachandran S, Chaney SG, Collins L, Swenberg JA, DeKrafft KE, Lin W, Cicurel L, Barbier M. Debio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells. Cancer Chemotherapy and Pharmacology. 69: 665-77. PMID 21968950 DOI: 10.1007/S00280-011-1744-3  0.398
2012 Kotapati S, Sangaraju D, Walker VE, Swenberg JA, Tretyakova NY. Abstract 4473: Urinary biomarkers of exposure to 1,3-Butadiene and its bioactivation to DNA-reactive metabolites Cancer Research. 72: 4473-4473. DOI: 10.1158/1538-7445.Am2012-4473  0.814
2012 Nakamura J, Tian X, Bultman S, Swenberg JA. Abstract 2552: Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system Cancer Research. 72: 2552-2552. DOI: 10.1158/1538-7445.Am2012-2552  0.373
2011 Bhattacharyya D, Ramachandran S, Sharma S, Pathmasiri W, King CL, Baskerville-Abraham I, Boysen G, Swenberg JA, Campbell SL, Dokholyan NV, Chaney SG. Flanking bases influence the nature of DNA distortion by platinum 1,2-intrastrand (GG) cross-links. Plos One. 6: e23582. PMID 21853154 DOI: 10.1371/Journal.Pone.0023582  0.812
2011 Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science (New York, N.Y.). 333: 1300-3. PMID 21778364 DOI: 10.1126/Science.1210597  0.384
2011 Simpkins JW, Swenberg JA, Weiss N, Brusick D, Eldridge JC, Stevens JT, Handa RJ, Hovey RC, Plant TM, Pastoor TP, Breckenridge CB. Atrazine and breast cancer: a framework assessment of the toxicological and epidemiological evidence. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 441-59. PMID 21768606 DOI: 10.1093/Toxsci/Kfr176  0.32
2011 Jung D, Matson CW, Collins LB, Laban G, Stapleton HM, Bickham JW, Swenberg JA, Di Giulio RT. Genotoxicity in Atlantic killifish (Fundulus heteroclitus) from a PAH-contaminated Superfund site on the Elizabeth River, Virginia. Ecotoxicology (London, England). 20: 1890-9. PMID 21706406 DOI: 10.1007/S10646-011-0727-9  0.435
2011 Koturbash I, Scherhag A, Sorrentino J, Sexton K, Bodnar W, Swenberg JA, Beland FA, Pardo-Manuel Devillena F, Rusyn I, Pogribny IP. Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 122: 448-56. PMID 21602187 DOI: 10.1093/Toxsci/Kfr133  0.436
2011 Begemann P, Boysen G, Georgieva NI, Sangaiah R, Koshlap KM, Koc H, Zhang D, Golding BT, Gold A, Swenberg JA. Identification and characterization of 2'-deoxyadenosine adducts formed by isoprene monoepoxides in vitro. Chemical Research in Toxicology. 24: 1048-61. PMID 21548641 DOI: 10.1021/Tx200055C  0.37
2011 Goggin M, Sangaraju D, Walker VE, Wickliffe J, Swenberg JA, Tretyakova N. Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation. Chemical Research in Toxicology. 24: 809-17. PMID 21452897 DOI: 10.1021/Tx200009B  0.826
2011 Moeller BC, Lu K, Doyle-Eisele M, McDonald J, Gigliotti A, Swenberg JA. Determination of N2-hydroxymethyl-dG adducts in the nasal epithelium and bone marrow of nonhuman primates following 13CD2-formaldehyde inhalation exposure. Chemical Research in Toxicology. 24: 162-4. PMID 21222454 DOI: 10.1021/Tx1004166  0.425
2011 Swenberg JA, Lu K, Moeller BC, Gao L, Upton PB, Nakamura J, Starr TB. Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: S130-45. PMID 21163908 DOI: 10.1093/Toxsci/Kfq371  0.651
2011 Lu K, Moeller B, Doyle-Eisele M, McDonald J, Swenberg JA. Molecular dosimetry of N2-hydroxymethyl-dG DNA adducts in rats exposed to formaldehyde. Chemical Research in Toxicology. 24: 159-61. PMID 21155545 DOI: 10.1021/Tx1003886  0.53
2011 Koturbash I, Scherhag A, Sorrentino J, Sexton K, Bodnar W, Tryndyak V, Latendresse JR, Swenberg JA, Beland FA, Pogribny IP, Rusyn I. Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene. Environmental Health Perspectives. 119: 635-40. PMID 21147608 DOI: 10.1289/Ehp.1002910  0.425
2011 Swenberg JA, Bordeerat NK, Boysen G, Carro S, Georgieva NI, Nakamura J, Troutman JM, Upton PB, Albertini RJ, Vacek PM, Walker VE, Sram RJ, Goggin M, Tretyakova N. 1,3-Butadiene: Biomarkers and application to risk assessment. Chemico-Biological Interactions. 192: 150-4. PMID 20974116 DOI: 10.1016/J.Cbi.2010.10.010  0.812
2011 Ridpath JR, Takeda S, Swenberg JA, Nakamura J. Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action. Environmental and Molecular Mutagenesis. 52: 153-60. PMID 20839229 DOI: 10.1002/Em.20595  0.415
2011 Swenberg JA, Bordeerat NK, Boysen G, Carro S, Georgieva NI, Nakamura J, Troutman JM, Upton PB, Albertini RJ, Vacek PM, Walker VE, Sram RJ, Goggin M, Tretyakova N. Corrigendum to "1,3-Butadiene: Biomarkers and application to risk assessment" (Chemico-Biological Interactions (2011) 192, 1-2, (150-154) DOI: 10.1016/j.cbi.2010.10.010) Chemico-Biological Interactions. 193: 190. DOI: 10.1016/J.Cbi.2011.06.008  0.749
2010 Luke AM, Chastain PD, Pachkowski BF, Afonin V, Takeda S, Kaufman DG, Swenberg JA, Nakamura J. Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. Mutation Research. 694: 65-71. PMID 20851134 DOI: 10.1016/J.Mrfmmm.2010.08.008  0.804
2010 Mutlu E, Collins LB, Stout MD, Upton PB, Daye LR, Winsett D, Hatch G, Evansky P, Swenberg JA. Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC. Chemical Research in Toxicology. 23: 1485-91. PMID 20799743 DOI: 10.1021/Tx1001767  0.753
2010 Goggin M, Seneviratne U, Swenberg JA, Walker VE, Tretyakova N. Column switching HPLC-ESI(+)-MS/MS methods for quantitative analysis of exocyclic dA adducts in the DNA of laboratory animals exposed to 1,3-butadiene. Chemical Research in Toxicology. 23: 808-12. PMID 20229982 DOI: 10.1021/Tx900439W  0.834
2010 Lu K, Ye W, Zhou L, Collins LB, Chen X, Gold A, Ball LM, Swenberg JA. Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers. Journal of the American Chemical Society. 132: 3388-99. PMID 20178313 DOI: 10.1021/Ja908282F  0.328
2010 Lu K, Collins LB, Ru H, Bermudez E, Swenberg JA. Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 441-51. PMID 20176625 DOI: 10.1093/Toxsci/Kfq061  0.529
2010 Georgieva NI, Boysen G, Bordeerat N, Walker VE, Swenberg JA. Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 322-9. PMID 20176624 DOI: 10.1093/Toxsci/Kfq060  0.808
2010 Boysen G, Collins LB, Liao S, Luke AM, Pachkowski BF, Watters JL, Swenberg JA. Analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine by ultra high pressure liquid chromatography-heat assisted electrospray ionization-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 375-80. PMID 20022307 DOI: 10.1016/J.Jchromb.2009.12.004  0.817
2010 King CL, Ramachandran S, Chaney SG, Collins L, Swenberg JA, deKrafft KE, Lin W, Cicurel L, Barbier M. Abstract 3504: Debio 0507 primarily forms diaminocyclohexane-d(GpG) and -d(ApG) DNA adducts in HCT116 cells Cancer Research. 70: 3504-3504. DOI: 10.1158/1538-7445.Am10-3504  0.427
2009 Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF. Genotoxicity of 1,3-butadiene and its epoxy intermediates. Research Report (Health Effects Institute). 3-79. PMID 20017413  0.308
2009 Pachkowski BF, Tano K, Afonin V, Elder RH, Takeda S, Watanabe M, Swenberg JA, Nakamura J. Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS. Mutation Research. 671: 93-9. PMID 19778542 DOI: 10.1016/J.Mrfmmm.2009.09.006  0.816
2009 Jarabek AM, Pottenger LH, Andrews LS, Casciano D, Embry MR, Kim JH, Preston RJ, Reddy MV, Schoeny R, Shuker D, Skare J, Swenberg J, Williams GM, Zeiger E. Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization. Critical Reviews in Toxicology. 39: 659-78. PMID 19743944 DOI: 10.1080/10408440903164155  0.482
2009 Jung D, Cho Y, Collins LB, Swenberg JA, Di Giulio RT. Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site. Aquatic Toxicology (Amsterdam, Netherlands). 95: 44-51. PMID 19726093 DOI: 10.1016/J.Aquatox.2009.08.003  0.477
2009 Bordeerat NK, Georgieva NI, Klapper DG, Collins LB, Cross TJ, Borchers CH, Swenberg JA, Boysen G. Accurate quantitation of standard peptides used for quantitative proteomics. Proteomics. 9: 3939-44. PMID 19637239 DOI: 10.1002/Pmic.200900043  0.771
2009 Kim S, Collins LB, Boysen G, Swenberg JA, Gold A, Ball LM, Bradford BU, Rusyn I. Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine. Toxicology. 262: 230-8. PMID 19549554 DOI: 10.1016/J.Tox.2009.06.013  0.343
2009 Il'yasova D, McCarthy BJ, Erdal S, Shimek J, Goldstein J, Doerge DR, Myers SR, Vineis P, Wishnok JS, Swenberg JA, Bigner DD, Davis FG. Human exposure to selected animal neurocarcinogens: a biomarker-based assessment and implications for brain tumor epidemiology. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 12: 175-87. PMID 19466671 DOI: 10.1080/10937400902894152  0.362
2009 Boysen G, Pachkowski BF, Nakamura J, Swenberg JA. The formation and biological significance of N7-guanine adducts. Mutation Research. 678: 76-94. PMID 19465146 DOI: 10.1016/J.Mrgentox.2009.05.006  0.825
2009 Bailey GS, Reddy AP, Pereira CB, Harttig U, Baird W, Spitsbergen JM, Hendricks JD, Orner GA, Williams DE, Swenberg JA. Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study. Chemical Research in Toxicology. 22: 1264-76. PMID 19449824 DOI: 10.1021/Tx9000754  0.324
2009 Baskerville-Abraham IM, Boysen G, Troutman JM, Mutlu E, Collins L, Dekrafft KE, Lin W, King C, Chaney SG, Swenberg JA. Development of an ultraperformance liquid chromatography/mass spectrometry method to quantify cisplatin 1,2 intrastrand guanine-guanine adducts. Chemical Research in Toxicology. 22: 905-12. PMID 19323581 DOI: 10.1021/Tx800481J  0.81
2009 Goggin M, Swenberg JA, Walker VE, Tretyakova N. Molecular dosimetry of 1,2,3,4-diepoxybutane-induced DNA-DNA cross-links in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation. Cancer Research. 69: 2479-86. PMID 19276346 DOI: 10.1158/0008-5472.Can-08-4152  0.842
2009 Lu K, Ye W, Gold A, Ball LM, Swenberg JA. Formation of S-[1-(N2-deoxyguanosinyl)methyl]glutathione between glutathione and DNA induced by formaldehyde. Journal of the American Chemical Society. 131: 3414-5. PMID 19239220 DOI: 10.1021/Ja808048C  0.502
2008 Reed MD, Barrett EG, Campen MJ, Divine KK, Gigliotti AP, McDonald JD, Seagrave JC, Mauderly JL, Seilkop SK, Swenberg JA. Health effects of subchronic inhalation exposure to gasoline engine exhaust. Inhalation Toxicology. 20: 1125-43. PMID 18800271 DOI: 10.1080/08958370802368722  0.347
2008 Lu K, Boysen G, Gao L, Collins LB, Swenberg JA. Formaldehyde-induced histone modifications in vitro. Chemical Research in Toxicology. 21: 1586-93. PMID 18656964 DOI: 10.1021/Tx8000576  0.618
2008 Jeong YC, Walker NJ, Burgin DE, Kissling G, Gupta M, Kupper L, Birnbaum LS, Swenberg JA. Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons. Free Radical Biology & Medicine. 45: 585-91. PMID 18534201 DOI: 10.1016/J.Freeradbiomed.2008.04.043  0.67
2008 Goggin M, Anderson C, Park S, Swenberg J, Walker V, Tretyakova N. Quantitative high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice. Chemical Research in Toxicology. 21: 1163-70. PMID 18442269 DOI: 10.1021/Tx800051Y  0.833
2008 Yano BL, Hardisty JF, Seely JC, Butterworth BE, McConnell EE, Swenberg JA, Williams GM, Stebbins KE, Golllapudi BB, Eisenbrandt DL. Nitrapyrin: a scientific advisory group review of the mode of action and carcinogenicity in B6C3F1 mice. Regulatory Toxicology and Pharmacology : Rtp. 51: 53-65. PMID 18367300 DOI: 10.1016/J.Yrtph.2008.02.001  0.352
2008 Stout MD, Bodes E, Schoonhoven R, Upton PB, Travlos GS, Swenberg JA. Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal. Toxicologic Pathology. 36: 232-46. PMID 18362197 DOI: 10.1177/0192623307311758  0.797
2008 Esther CR, Jasin HM, Collins LB, Swenberg JA, Boysen G. A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate. Rapid Communications in Mass Spectrometry : Rcm. 22: 701-5. PMID 18257110 DOI: 10.1002/Rcm.3408  0.313
2008 Swenberg JA, Fryar-Tita E, Jeong YC, Boysen G, Starr T, Walker VE, Albertini RJ. Biomarkers in toxicology and risk assessment: informing critical dose-response relationships. Chemical Research in Toxicology. 21: 253-65. PMID 18161944 DOI: 10.1021/Tx700408T  0.644
2007 Ridpath JR, Nakamura A, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde JM, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA, et al. Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde. Cancer Research. 67: 11117-22. PMID 18056434 DOI: 10.1158/0008-5472.Can-07-3028  0.442
2007 Brooks NL, Trent CM, Raetzsch CF, Flurkey K, Boysen G, Perfetti MT, Jeong YC, Klebanov S, Patel KB, Khodush VR, Kupper LL, Carling D, Swenberg JA, Harrison DE, Combs TP. Low utilization of circulating glucose after food withdrawal in Snell dwarf mice. The Journal of Biological Chemistry. 282: 35069-77. PMID 17905742 DOI: 10.1074/Jbc.M700484200  0.495
2007 Watters JL, Satia JA, Kupper LL, Swenberg JA, Schroeder JC, Switzer BR. Associations of antioxidant nutrients and oxidative DNA damage in healthy African-American and White adults. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1428-36. PMID 17627008 DOI: 10.1158/1055-9965.Epi-06-1030  0.38
2007 Wu Y, Bhattacharyya D, King CL, Baskerville-Abraham I, Huh SH, Boysen G, Swenberg JA, Temple B, Campbell SL, Chaney SG. Solution structures of a DNA dodecamer duplex with and without a cisplatin 1,2-d(GG) intrastrand cross-link: comparison with the same DNA duplex containing an oxaliplatin 1,2-d(GG) intrastrand cross-link. Biochemistry. 46: 6477-87. PMID 17497831 DOI: 10.1021/Bi062291F  0.817
2007 Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 366-74. PMID 17483499 DOI: 10.1093/Toxsci/Kfm104  0.34
2007 Powley MW, Walker VE, Li Y, Upton PB, Swenberg JA. The importance of 3,4-epoxy-1,2-butanediol and hydroxymethylvinyl ketone in 3-butene-1,2-diol associated mutagenicity. Chemico-Biological Interactions. 166: 182-90. PMID 17349618 DOI: 10.1016/J.Cbi.2007.02.001  0.513
2007 Pottenger LH, Malley LA, Bogdanffy MS, Donner EM, Upton PB, Li Y, Walker VE, Harkema JR, Banton MI, Swenberg JA. Evaluation of effects from repeated inhalation exposure of F344 rats to high concentrations of propylene. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 336-47. PMID 17341482 DOI: 10.1093/Toxsci/Kfm038  0.446
2007 Takahashi N, Boysen G, Li F, Li Y, Swenberg JA. Tandem mass spectrometry measurements of creatinine in mouse plasma and urine for determining glomerular filtration rate. Kidney International. 71: 266-71. PMID 17149371 DOI: 10.1038/Sj.Ki.5002033  0.335
2007 Boysen G, Georgieva NI, Upton PB, Walker VE, Swenberg JA. N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides. Chemico-Biological Interactions. 166: 84-92. PMID 17084829 DOI: 10.1016/J.Cbi.2006.10.005  0.441
2007 Albertini RJ, Sram RJ, Vacek PM, Lynch J, Rossner P, Nicklas JA, McDonald JD, Boysen G, Georgieva N, Swenberg JA. Molecular epidemiological studies in 1,3-butadiene exposed Czech workers: female-male comparisons. Chemico-Biological Interactions. 166: 63-77. PMID 16949064 DOI: 10.1016/J.Cbi.2006.07.004  0.345
2007 Meng Q, Walker DM, McDonald JD, Henderson RF, Carter MM, Cook DL, McCash CL, Torres SM, Bauer MJ, Seilkop SK, Upton PB, Georgieva NI, Boysen G, Swenberg JA, Walker VE. Age-, gender-, and species-dependent mutagenicity in T cells of mice and rats exposed by inhalation to 1,3-butadiene. Chemico-Biological Interactions. 166: 121-31. PMID 16945358 DOI: 10.1016/J.Cbi.2006.07.005  0.358
2006 Chastain PD, Nakamura J, Swenberg J, Kaufman D. Nonrandom AP site distribution in highly proliferative cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2612-4. PMID 17068113 DOI: 10.1096/Fj.06-6145Fje  0.349
2006 Powell CL, Kosyk O, Ross PK, Schoonhoven R, Boysen G, Swenberg JA, Heinloth AN, Boorman GA, Cunningham ML, Paules RS, Rusyn I. Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 213-22. PMID 16751229 DOI: 10.1093/Toxsci/Kfl030  0.346
2006 Stout MD, Jeong YC, Boysen G, Li Y, Sangaiah R, Ball LM, Gold A, Swenberg JA. LC/MS/MS method for the quantitation of trans-2-hexenal-derived exocyclic 1,N(2)-propanodeoxyguanosine in DNA. Chemical Research in Toxicology. 19: 563-70. PMID 16608168 DOI: 10.1021/Tx050346T  0.821
2006 Pachkowski BF, Winkel S, Kubota Y, Swenberg JA, Millikan RC, Nakamura J. XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Research. 66: 2860-8. PMID 16510609 DOI: 10.1158/0008-5472.Can-05-3388  0.782
2006 Swenberg J, Boysen G, Georgieva N, Morinello E, Upton P, Walker V. Dose, tissue and species transitions in biomarkers Toxicology. 226: 20-21. DOI: 10.1016/J.Tox.2006.05.032  0.713
2005 Jeong YC, Nakamura J, Upton PB, Swenberg JA. Pyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation. Nucleic Acids Research. 33: 6426-34. PMID 16282591 DOI: 10.1093/Nar/Gki944  0.644
2005 Jeong YC, Swenberg JA. Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals. Free Radical Biology & Medicine. 39: 1021-9. PMID 16198229 DOI: 10.1016/J.Freeradbiomed.2005.05.018  0.59
2005 Powell CL, Swenberg JA, Rusyn I. Expression of base excision DNA repair genes as a biomarker of oxidative DNA damage. Cancer Letters. 229: 1-11. PMID 16157213 DOI: 10.1016/J.Canlet.2004.12.002  0.451
2005 Rusyn I, Asakura S, Li Y, Kosyk O, Koc H, Nakamura J, Upton PB, Swenberg JA. Effects of ethylene oxide and ethylene inhalation on DNA adducts, apurinic/apyrimidinic sites and expression of base excision DNA repair genes in rat brain, spleen, and liver. Dna Repair. 4: 1099-110. PMID 16051529 DOI: 10.1016/J.Dnarep.2005.05.009  0.488
2005 Weis BK, Balshaw D, Barr JR, Brown D, Ellisman M, Lioy P, Omenn G, Potter JD, Smith MT, Sohn L, Suk WA, Sumner S, Swenberg J, Walt DR, Watkins S, et al. Personalized exposure assessment: promising approaches for human environmental health research. Environmental Health Perspectives. 113: 840-8. PMID 16002370 DOI: 10.1289/Ehp.7651  0.325
2005 Chiang SY, Huang TH, Uang SN, Wu HD, Wei YC, Lin HY, Swenberg JA, Wu KY. Analysis of 7-methylguanine using isotope dilution and gas chromatography/electron-capture negative chemical ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 19: 1915-20. PMID 15954176 DOI: 10.1002/Rcm.2003  0.372
2005 Powley MW, Li Y, Upton PB, Walker VE, Swenberg JA. Quantification of DNA and hemoglobin adducts of 3,4-epoxy-1,2-butanediol in rodents exposed to 3-butene-1,2-diol. Carcinogenesis. 26: 1573-80. PMID 15888494 DOI: 10.1093/Carcin/Bgi119  0.459
2005 McDorman KS, Pachkowski BF, Nakamura J, Wolf DC, Swenberg JA. Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products. Chemico-Biological Interactions. 152: 107-17. PMID 15840384 DOI: 10.1016/J.Cbi.2005.02.003  0.813
2005 Lin CH, Leow HT, Huang SC, Nakamura J, Swenberg JA, Lin PH. Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells. Chemical Research in Toxicology. 18: 257-64. PMID 15720130 DOI: 10.1021/Tx0498511  0.462
2005 Jeong YC, Sangaiah R, Nakamura J, Pachkowski BF, Ranasinghe A, Gold A, Ball LM, Swenberg JA. Analysis of M1G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry. Chemical Research in Toxicology. 18: 51-60. PMID 15651849 DOI: 10.1021/Tx049853L  0.829
2004 Slikker W, Andersen ME, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM, Doerrer NG, Dorman DC, Gaylor DW, Hattis D, Rogers JM, Setzer RW, Swenberg JA, Wallace K. Dose-dependent transitions in mechanisms of toxicity: case studies. Toxicology and Applied Pharmacology. 201: 226-94. PMID 15582646 DOI: 10.1016/J.Taap.2004.06.027  0.31
2004 Boysen G, Georgieva NI, Upton PB, Jayaraj K, Li Y, Walker VE, Swenberg JA. Analysis of diepoxide-specific cyclic N-terminal globin adducts in mice and rats after inhalation exposure to 1,3-butadiene. Cancer Research. 64: 8517-20. PMID 15574756 DOI: 10.1158/0008-5472.Can-04-3184  0.442
2004 Wu Y, Pradhan P, Havener J, Boysen G, Swenberg JA, Campbell SL, Chaney SG. NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex. Journal of Molecular Biology. 341: 1251-69. PMID 15321720 DOI: 10.1016/J.Jmb.2004.06.066  0.332
2004 Ham AJ, Engelward BP, Koc H, Sangaiah R, Meira LB, Samson LD, Swenberg JA. New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo. Dna Repair. 3: 257-65. PMID 15177041 DOI: 10.1016/J.Dnarep.2003.11.003  0.47
2004 Zielinska-Park J, Nakamura J, Swenberg JA, Aitken MD. Aldehydic DNA lesions in calf thymus DNA and HeLa S3 cells produced by bacterial quinone metabolites of fluoranthene and pyrene. Carcinogenesis. 25: 1727-33. PMID 15117810 DOI: 10.1093/Carcin/Bgh174  0.469
2004 Hu CW, Wu MT, Chao MR, Pan CH, Wang CJ, Swenberg JA, Wu KY. Comparison of analyses of urinary 8-hydroxy-2'-deoxyguanosine by isotope-dilution liquid chromatography with electrospray tandem mass spectrometry and by enzyme-linked immunosorbent assay. Rapid Communications in Mass Spectrometry : Rcm. 18: 505-10. PMID 14966860 DOI: 10.1002/Rcm.1367  0.349
2004 Rusyn I, Asakura S, Pachkowski B, Bradford BU, Denissenko MF, Peters JM, Holland SM, Reddy JK, Cunningham ML, Swenberg JA. Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators. Cancer Research. 64: 1050-7. PMID 14871837 DOI: 10.1158/0008-5472.Can-03-3027  0.826
2003 Calderón-Garcidueñas L, Maronpot RR, Torres-Jardon R, Henríquez-Roldán C, Schoonhoven R, Acuña-Ayala H, Villarreal-Calderón A, Nakamura J, Fernando R, Reed W, Azzarelli B, Swenberg JA. DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration. Toxicologic Pathology. 31: 524-38. PMID 14692621 DOI: 10.1080/01926230390226645  0.335
2003 Barbin A, Ohgaki H, Nakamura J, Kurrer M, Kleihues P, Swenberg JA. Endogenous deoxyribonucleic Acid (DNA) damage in human tissues: a comparison of ethenobases with aldehydic DNA lesions. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 12: 1241-7. PMID 14652288  0.314
2003 Powley MW, Jayaraj K, Gold A, Ball LM, Swenberg JA. 1,N2-propanodeoxyguanosine adducts of the 1,3-butadiene metabolite, hydroxymethylvinyl ketone. Chemical Research in Toxicology. 16: 1448-54. PMID 14615971 DOI: 10.1021/Tx030021H  0.435
2003 Nakamura J, Asakura S, Hester SD, de Murcia G, Caldecott KW, Swenberg JA. Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time. Nucleic Acids Research. 31: e104. PMID 12930978 DOI: 10.1093/Nar/Gng105  0.416
2003 Lin PH, Nakamura J, Yamaguchi S, Asakura S, Swenberg JA. Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA. Carcinogenesis. 24: 1133-41. PMID 12807746 DOI: 10.1093/Carcin/Bgg049  0.414
2003 Jayaraj K, Georgieva NI, Gold A, Sangaiah R, Koc H, Klapper DG, Ball LM, Reddy AP, Swenberg JA. Synthesis and characterization of peptides containing a cyclic Val adduct of diepoxybutane, a possible biomarker of human exposure to butadiene. Chemical Research in Toxicology. 16: 637-43. PMID 12755593 DOI: 10.1021/Tx020099I  0.36
2003 Albertini R, Clewell H, Himmelstein MW, Morinello E, Olin S, Preston J, Scarano L, Smith MT, Swenberg J, Tice R, Travis C. The use of non-tumor data in cancer risk assessment: Reflections on butadiene, vinyl chloride, and benzene Regulatory Toxicology and Pharmacology. 37: 105-132. PMID 12662914 DOI: 10.1016/S0273-2300(02)00019-3  0.725
2003 Nakamura J, Purvis ER, Swenberg JA. Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells. Nucleic Acids Research. 31: 1790-5. PMID 12626721 DOI: 10.1093/Nar/Gkg263  0.437
2003 Horton JK, Joyce-Gray DF, Pachkowski BF, Swenberg JA, Wilson SH. Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. Dna Repair. 2: 27-48. PMID 12509266 DOI: 10.1016/S1568-7864(02)00184-2  0.813
2002 Swenberg JA, Ham AJ, Koc H, La DK, Morinello EJ, Pachkowski BF, Ranasinghe A, Upton PB. Methods for measuring DNA adducts and abasic sites II: methods for measurement of DNA adducts. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit3.9. PMID 23045080 DOI: 10.1002/0471140856.Tx0309S12  0.818
2002 Swenberg JA, Ham AJ, McDorman KS, Morinello EJ, Nakamura J, Schoonhoven R. Methods for measuring DNA adducts and abasic sites I: isolation, purification, and analysis of DNA adducts in intact DNA. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit3.8. PMID 23045079 DOI: 10.1002/0471140856.Tx0308S12  0.835
2002 Koc H, Swenberg JA. Applications of mass spectrometry for quantitation of DNA adducts. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 778: 323-43. PMID 12376138 DOI: 10.1016/S1570-0232(02)00135-6  0.472
2002 Koc H, Mar MH, Ranasinghe A, Swenberg JA, Zeisel SH. Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry. Analytical Chemistry. 74: 4734-40. PMID 12349977 DOI: 10.1021/Ac025624X  0.313
2002 Morinello EJ, Ham AJ, Ranasinghe A, Nakamura J, Upton PB, Swenberg JA. Molecular dosimetry and repair of N(2),3-ethenoguanine in rats exposed to vinyl chloride. Cancer Research. 62: 5189-95. PMID 12234983  0.775
2002 Morinello EJ, Koc H, Ranasinghe A, Swenberg JA. Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride. Cancer Research. 62: 5183-8. PMID 12234982  0.784
2002 Richardson FC, Zhang C, Lehrman SR, Koc H, Swenberg JA, Richardson KA, Bendele RA. Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS. Chemical Research in Toxicology. 15: 922-6. PMID 12119002 DOI: 10.1021/Tx020014D  0.479
2002 Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 99: 6860-5. PMID 11983862 DOI: 10.1073/Pnas.092662499  0.422
2002 Swenberg JA, Gorgeiva N, Ham A, Koc H, Morinello E, Ranasinghe A, Upton P, Walker V. Linking pharmacokinetics and biomarker data to mechanism of action in risk assessment Human and Ecological Risk Assessment. 8: 1315-1338. DOI: 10.1080/20028091057385  0.756
2001 Swenberg JA, Koc H, Upton PB, Georguieva N, Ranasinghe A, Walker VE, Henderson R. Using DNA and hemoglobin adducts to improve the risk assessment of butadiene. Chemico-Biological Interactions. 135: 387-403. PMID 11397403 DOI: 10.1016/S0009-2797(01)00221-6  0.468
2001 Meng Q, Henderson RF, Long L, Blair L, Walker DM, Upton PB, Swenberg JA, Walker VE. Mutagenicity at the Hprt locus in T cells of female mice following inhalation exposures to low levels of 1,3-butadiene. Chemico-Biological Interactions. 135: 343-61. PMID 11397400 DOI: 10.1016/S0009-2797(01)00222-8  0.358
2001 McKim JM, Kolesar GB, Jean PA, Meeker LS, Wilga PC, Schoonhoven R, Swenberg JA, Goodman JI, Gallavan RH, Meeks RG. Repeated inhalation exposure to octamethylcyclotetrasiloxane produces hepatomegaly, transient hepatic hyperplasia, and sustained hypertrophy in female Fischer 344 rats in a manner similar to phenobarbital. Toxicology and Applied Pharmacology. 172: 83-92. PMID 11298494 DOI: 10.1006/Taap.2000.9110  0.341
2001 Lin PH, Nakamura J, Yamaguchi S, La DK, Upton PB, Swenberg JA. Induction of direct adducts, apurinic/apyrimidinic sites and oxidized bases in nuclear DNA of human HeLa S3 tumor cells by tetrachlorohydroquinone. Carcinogenesis. 22: 635-9. PMID 11285200 DOI: 10.1093/Carcin/22.4.635  0.458
2001 Lin PH, Nakamura J, Yamaguchi S, Upton PB, La DK, Swenberg JA. Oxidative damage and direct adducts in calf thymus DNA induced by the pentachlorophenol metabolites, tetrachlorohydroquinone and tetrachloro-1,4-benzoquinone. Carcinogenesis. 22: 627-34. PMID 11285199 DOI: 10.1093/Carcin/22.4.627  0.417
2001 Morinello EJ, Ham AJ, Ranasinghe A, Sangaiah R, Swenberg JA. Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay. Chemical Research in Toxicology. 14: 327-34. PMID 11258983 DOI: 10.1021/Tx0002076  0.78
2000 Rusyn I, Denissenko MF, Wong VA, Butterworth BE, Cunningham ML, Upton PB, Thurman RG, Swenberg JA. Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency. Carcinogenesis. 21: 2141-5. PMID 11133801 DOI: 10.1093/Carcin/21.12.2141  0.47
2000 Ham AJ, Ranasinghe A, Koc H, Swenberg JA. 4-Hydroxy-2-nonenal and ethyl linoleate form N(2),3-ethenoguanine under peroxidizing conditions. Chemical Research in Toxicology. 13: 1243-50. PMID 11123965 DOI: 10.1021/Tx0001124  0.37
2000 Ríos-Blanco MN, Faller TH, Nakamura J, Kessler W, Kreuzer PE, Ranasinghe A, Filser JG, Swenberg JA. Quantitation of DNA and hemoglobin adducts and apurinic/apyrimidinic sites in tissues of F344 rats exposed to propylene oxide by inhalation. Carcinogenesis. 21: 2011-8. PMID 11062162 DOI: 10.1093/Carcin/21.11.2011  0.496
2000 Walker VE, Wu KY, Upton PB, Ranasinghe A, Scheller N, Cho MH, Vergnes JS, Skopek TR, Swenberg JA. Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide. Carcinogenesis. 21: 1661-9. PMID 10964097 DOI: 10.1093/Carcin/21.9.1661  0.41
2000 Holt S, Roy G, Mitra S, Upton PB, Bogdanffy MS, Swenberg JA. Deficiency of N-methylpurine-DNA-glycosylase expression in nonparenchymal cells, the target cell for vinyl chloride and vinyl fluoride. Mutation Research. 460: 105-15. PMID 10882851 DOI: 10.1016/S0921-8777(00)00019-7  0.447
2000 Nakamura J, La DK, Swenberg JA. 5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress. The Journal of Biological Chemistry. 275: 5323-8. PMID 10681505 DOI: 10.1074/Jbc.275.8.5323  0.381
2000 Swenberg JA, Ham A, Koc H, Morinello E, Ranasinghe A, Tretyakova N, Upton PB, Wu K. DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene. Mutation Research. 464: 77-86. PMID 10633179 DOI: 10.1016/S1383-5718(99)00168-0  0.842
1999 Swenberg JA, Bogdanffy MS, Ham A, Holt S, Kim A, Morinello EJ, Ranasinghe A, Scheller N, Upton PB. Formation and repair of DNA adducts in vinyl chloride- and vinyl fluoride-induced carcinogenesis. Iarc Scientific Publications. 29-43. PMID 10626206  0.788
1999 Ham AJ, Ranasinghe A, Morinello EJ, Nakamura J, Upton PB, Johnson F, Swenberg JA. Immunoaffinity/gas chromatography/high-resolution mass spectrometry method for the detection of N(2),3-ethenoguanine. Chemical Research in Toxicology. 12: 1240-6. PMID 10604874 DOI: 10.1021/Tx990150R  0.811
1999 Wang SS, O'Neill JP, Qian GS, Zhu YR, Wang JB, Armenian H, Zarba A, Wang JS, Kensler TW, Cariello NF, Groopman JD, Swenberg JA. Elevated HPRT mutation frequencies in aflatoxin-exposed residents of daxin, Qidong county, People's Republic of China. Carcinogenesis. 20: 2181-4. PMID 10545423 DOI: 10.1093/Carcin/20.11.2181  0.344
1999 Eide I, Zhao C, Kumar R, Hemminki K, Wu Ky, Swenberg JA. Comparison of (32)P-postlabeling and high-resolution GC/MS in quantifying N7-(2-Hydroxyethyl)guanine adducts. Chemical Research in Toxicology. 12: 979-84. PMID 10525275 DOI: 10.1021/Tx990039L  0.444
1999 Wu KY, Ranasinghe A, Upton PB, Walker VE, Swenberg JA. Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents. Carcinogenesis. 20: 1787-92. PMID 10469625 DOI: 10.1093/Carcin/20.9.1787  0.398
1999 Wu KY, Scheller N, Ranasinghe A, Yen TY, Sangaiah R, Giese R, Swenberg JA. A gas chromatography/electron capture/negative chemical ionization high-resolution mass spectrometry method for analysis of endogenous and exogenous N7-(2-hydroxyethyl)guanine in rodents and its potential for human biological monitoring. Chemical Research in Toxicology. 12: 722-9. PMID 10458706 DOI: 10.1021/Tx990059N  0.445
1999 Koc H, Tretyakova NY, Walker VE, Henderson RF, Swenberg JA. Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene. Chemical Research in Toxicology. 12: 566-74. PMID 10409395 DOI: 10.1021/Tx980265F  0.697
1999 Lin PH, Waidyanatha S, Pollack GM, Swenberg JA, Rappaport SM. Dose-specific production of chlorinated quinone and semiquinone adducts in rodent livers following administration of pentachlorophenol. Toxicological Sciences : An Official Journal of the Society of Toxicology. 47: 126-33. PMID 10048161 DOI: 10.1093/Toxsci/47.1.126  0.335
1998 Tretyakova NYu, Chiang SY, Walker VE, Swenberg JA. Quantitative analysis of 1,3-butadiene-induced DNA adducts in vivo and in vitro using liquid chromatography electrospray ionization tandem mass spectrometry. Journal of Mass Spectrometry : Jms. 33: 363-76. PMID 9597770 DOI: 10.1002/(Sici)1096-9888(199804)33:4<363::Aid-Jms643>3.0.Co;2-E  0.498
1998 Law JM, Bull M, Nakamura J, Swenberg JA. Molecular dosimetry of DNA adducts in the medaka small fish model. Carcinogenesis. 19: 515-8. PMID 9525288 DOI: 10.1093/carcin/19.3.515  0.367
1997 Ríos-Blanco MN, Plna K, Faller T, Kessler W, HÃ¥kansson K, Kreuzer PE, Ranasinghe A, Filser JG, Segerbäck D, Swenberg JA. Propylene oxide: mutagenesis, carcinogenesis and molecular dose. Mutation Research. 380: 179-97. PMID 9385398 DOI: 10.1016/S0027-5107(97)00135-8  0.481
1997 Tretyakova N, Sangaiah R, Yen TY, Gold A, Swenberg JA. Adenine adducts with diepoxybutane: isolation and analysis in exposed calf thymus DNA. Chemical Research in Toxicology. 10: 1171-9. PMID 9348440 DOI: 10.1021/Tx9700681  0.693
1997 Swenberg JA, Beauchamp RO. A review of the chronic toxicity, carcinogenicity, and possible mechanisms of action of inorganic acid mists in animals. Critical Reviews in Toxicology. 27: 253-9. PMID 9189654 DOI: 10.3109/10408449709089894  0.334
1997 Tretyakova N, Lin Y, Sangaiah R, Upton PB, Swenberg JA. Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene. Carcinogenesis. 18: 137-47. PMID 9054600 DOI: 10.1093/Carcin/18.1.137  0.671
1994 Osterman-Golkar SM, MacNeela JP, Turner MJ, Walker VE, Swenberg JA, Sumner SJ, Youtsey N, Fennell TR. Monitoring exposure to acrylonitrile using adducts with N-terminal valine in hemoglobin. Carcinogenesis. 15: 2701-7. PMID 8001224 DOI: 10.1093/Carcin/15.12.2701  0.363
1994 McConnell EE, Swenberg JA. Review of styrene and styrene oxide long-term animal studies. Critical Reviews in Toxicology. 24: S49-55. PMID 7818772 DOI: 10.3109/10408449409020141  0.347
1993 Walker VE, Fennell TR, Upton PB, MacNeela JP, Swenberg JA. Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide. Environmental Health Perspectives. 99: 11-7. PMID 8319608 DOI: 10.1289/Ehp.939911  0.483
1992 Walker VE, Fennell TR, Upton PB, Skopek TR, Prevost V, Shuker DE, Swenberg JA. Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice. Cancer Research. 52: 4328-34. PMID 1643630  0.394
1990 Fedtke N, Boucheron JA, Walker VE, Swenberg JA. Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA. Carcinogenesis. 11: 1287-92. PMID 2387014 DOI: 10.1093/carcin/11.8.1287  0.386
1990 Walker VE, Fennell TR, Boucheron JA, Fedtke N, Ciroussel F, Swenberg JA. Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation. Mutation Research. 233: 151-64. PMID 2233797 DOI: 10.1016/0027-5107(90)90159-2  0.349
1989 Schold SC, Brent TP, von Hofe E, Friedman HS, Mitra S, Bigner DD, Swenberg JA, Kleihues P. O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts. Journal of Neurosurgery. 70: 573-7. PMID 2926498 DOI: 10.3171/Jns.1989.70.4.0573  0.37
1989 Fedtke N, Walker VE, Swenberg JA. Determination of 7-(2-oxoethyl)guanine and N2,3-ethenoguanine in DNA hydrolysates by HPLC. Archives of Toxicology. Supplement. = Archiv Fã¼R Toxikologie. Supplement. 13: 214-8. PMID 2774932 DOI: 10.1007/978-3-642-74117-3_33  0.459
1987 Belinsky SA, White CM, Devereux TR, Swenberg JA, Anderson MW. Cell selective alkylation of DNA in rat lung following low dose exposure to the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Research. 47: 1143-8. PMID 3802095  0.311
1987 Richardson KK, Richardson FC, Crosby RM, Swenberg JA, Skopek TR. DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea. Proceedings of the National Academy of Sciences of the United States of America. 84: 344-8. PMID 3540961 DOI: 10.1073/Pnas.84.2.344  0.356
1986 Belinsky SA, White CM, Boucheron JA, Richardson FC, Swenberg JA, Anderson M. Accumulation and persistence of DNA adducts in respiratory tissue of rats following multiple administrations of the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Research. 46: 1280-4. PMID 3943097  0.355
1986 McConnell EE, Solleveld HA, Swenberg JA, Boorman GA. Guidelines for combining neoplasms for evaluation of rodent carcinogenesis studies. Journal of the National Cancer Institute. 76: 283-9. PMID 3456066 DOI: 10.1093/Jnci/76.2.283  0.309
1986 Dyroff MC, Richardson FC, Popp JA, Bedell MA, Swenberg JA. Correlation of O4-ethyldeoxythymidine accumulation, hepatic initiation and hepatocellular carcinoma induction in rats continuously administered diethylnitrosamine. Carcinogenesis. 7: 241-6. PMID 2868805 DOI: 10.1093/Carcin/7.2.241  0.343
1985 Popp JA, Garvey LK, Hamm TE, Swenberg JA. Lack of hepatic promotional activity by the peroxisomal proliferating hepatocarcinogen di(2-ethylhexyl)phthalate. Carcinogenesis. 6: 141-4. PMID 2857115 DOI: 10.1093/Carcin/6.1.141  0.303
1984 Cavender FL, Casey HW, Salem H, Graham DG, Swenberg JA, Gralla EJ. A 13-week vapor inhalation study of n-hexane in rats with emphasis on neurotoxic effects. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: 191-201. PMID 6724193 DOI: 10.1093/Toxsci/4.2Part1.191  0.33
1984 Swenberg JA, Dyroff MC, Bedell MA, Popp JA, Huh N, Kirstein U, Rajewsky MF. O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine. Proceedings of the National Academy of Sciences of the United States of America. 81: 1692-5. PMID 6584902 DOI: 10.1073/Pnas.81.6.1692  0.378
1984 Toorchen D, Lindamood C, Swenberg JA, Topal MD. O6-Methylguanine-DNA transmethylase converts O6-methylguanine thymine base pairs to guanine thymine base pairs in DNA. Carcinogenesis. 5: 1733-5. PMID 6499126 DOI: 10.1093/Carcin/5.12.1733  0.404
1983 Swenberg JA, Bedell MA, Billings KC, Lewis JG. Cell specificity in DNA damage and repair. Basic Life Sciences. 24: 605-17. PMID 6860276 DOI: 10.1007/978-1-4684-4400-1_32  0.391
1983 Swenberg JA, Rickert DE, Baranyi BL, Goodman JI. Cell specificity in DNA binding and repair of chemical carcinogens. Environmental Health Perspectives. 49: 155-63. PMID 6832089 DOI: 10.1289/ehp.8349155  0.334
1983 Lewis JG, Swenberg JA. The kinetics of DNA alkylation, repair and replication in hepatocytes, Kupffer cells, and sinusoidal endothelial cells in rat liver during continuous exposure to 1,2-dimethylhydrazine. Carcinogenesis. 4: 529-36. PMID 6189632 DOI: 10.1093/Carcin/4.5.529  0.405
1982 Belinsky SA, Bedell MA, Swenberg JA. Effect of chronic ethanol diet on the replication, alkylation, and repair of DNA from hepatocytes and nonparenchymal cells following dimethylnitrosamine administration. Carcinogenesis. 3: 1293-7. PMID 7151247 DOI: 10.1093/Carcin/3.11.1293  0.415
1978 Petzold G, Harbach P, Bedell M, Swenberg J. In vivo DNA damage/alkaline elution assay for predicting carcinogenic potential Mutation Research/Environmental Mutagenesis and Related Subjects. 53: 110. DOI: 10.1016/0165-1161(78)90456-9  0.337
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