Juan C. Troncoso, MD - Publications

Affiliations: 
Pathology Johns Hopkins School of Medicine 
Area:
human neurodegenerative disorders, in particular Alzheimer's disease
Website:
http://www.alzresearch.org/team.cfm?ID=2

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Year Citation  Score
2019 Hishimoto A, Pletnikova O, Lang DL, Troncoso JC, Egan JM, Liu QR. Correction to: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease. Alzheimer's Research & Therapy. 11: 39. PMID 31060630 DOI: 10.1186/s13195-019-0493-0  0.4
2019 Guerreiro R, Escott-Price V, Hernandez DG, Kun-Rodrigues C, Ross OA, Orme T, Neto JL, Carmona S, Dehghani N, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, ... Troncoso JC, et al. Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease. PMID 30953760 DOI: 10.1016/j.nbd.2019.04.004  0.4
2019 Hishimoto A, Pletnikova O, Lang DL, Troncoso JC, Egan JM, Liu QR. Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease. Alzheimer's Research & Therapy. 11: 28. PMID 30902061 DOI: 10.1186/s13195-019-0475-2  0.4
2019 Horti AG, Naik R, Foss CA, Minn I, Misheneva V, Du Y, Wang Y, Mathews WB, Wu Y, Hall A, LaCourse C, Ahn HH, Nam H, Lesniak WG, Valentine H, ... ... Troncoso JC, et al. PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R). Proceedings of the National Academy of Sciences of the United States of America. PMID 30635412 DOI: 10.1073/pnas.1812155116  0.56
2018 Blauwendraat C, Pletnikova O, Geiger JT, Murphy NA, Abramzon Y, Rudow G, Mamais A, Sabir MS, Crain B, Ahmed S, Rosenthal LS, Bakker CC, Faghri F, Chia R, Ding J, ... ... Troncoso JC, et al. Genetic analysis of neurodegenerative diseases in a pathology cohort. Neurobiology of Aging. PMID 30528841 DOI: 10.1016/j.neurobiolaging.2018.11.007  0.8
2018 Bell WR, An Y, Kageyama Y, English C, Rudow GL, Pletnikova O, Thambisetty M, O'Brien R, Moghekar AR, Albert MS, Rabins PV, Resnick SM, Troncoso JC. Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30465754 DOI: 10.1016/j.jalz.2018.07.215  0.4
2018 Kun-Rodrigues C, Orme T, Carmona S, Hernandez DG, Ross OA, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Dawson T, Rosenthal L, et al. A comprehensive screening of copy number variability in dementia with Lewy bodies. Neurobiology of Aging. PMID 30448004 DOI: 10.1016/j.neurobiolaging.2018.10.019  0.4
2018 Kageyama Y, Saito A, Pletnikova O, Rudow GL, Irie Y, An Y, Murakami K, Irie K, Resnick SM, Fowler DR, Martin LJ, Troncoso JC. Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques. Scientific Reports. 8: 16895. PMID 30442978 DOI: 10.1038/s41598-018-35004-3  0.52
2018 Kam TI, Mao X, Park H, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmachari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, et al. Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease. Science (New York, N.Y.). 362. PMID 30385548 DOI: 10.1126/science.aat8407  0.4
2018 Oh ES, Blennow K, Bigelow GE, Inouye SK, Marcantonio ER, Neufeld KJ, Rosenberg PB, Troncoso JC, Wang NY, Zetterberg H, Sieber FE, Lyketsos CG. Abnormal CSF amyloid-β42 and tau levels in hip fracture patients without dementia. Plos One. 13: e0204695. PMID 30252906 DOI: 10.1371/journal.pone.0204695  0.32
2018 Pletnikova O, Kageyama Y, Rudow G, LaClair KD, Albert M, Crain BJ, Tian J, Fowler D, Troncoso JC. The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype. Neurobiology of Aging. 71: 72-80. PMID 30099348 DOI: 10.1016/j.neurobiolaging.2018.07.007  0.8
2018 Hinkle JT, Perepezko K, Bakker CC, Broen MPG, Chin K, Dawson TM, Johnson V, Mari Z, Marvel CL, Mills KA, Pantelyat A, Pletnikova O, Rosenthal LS, Shepard MD, Stevens DA, ... Troncoso JC, et al. Onset and Remission of Psychosis in Parkinson's Disease: Pharmacologic and Motoric Markers. Movement Disorders Clinical Practice. 5: 31-38. PMID 29756003 DOI: 10.1002/mdc3.12550  0.4
2018 Varma VR, Oommen AM, Varma S, Casanova R, An Y, Andrews RM, O'Brien R, Pletnikova O, Troncoso JC, Toledo J, Baillie R, Arnold M, Kastenmueller G, Nho K, Doraiswamy PM, et al. Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study. Plos Medicine. 15: e1002482. PMID 29370177 DOI: 10.1371/journal.pmed.1002482  0.4
2018 Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, et al. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. The Lancet. Neurology. 17: 64-74. PMID 29263008 DOI: 10.1016/S1474-4422(17)30400-3  0.4
2017 Todd KL, Brighton T, Norton ES, Schick S, Elkins W, Pletnikova O, Fortinsky RH, Troncoso JC, Molfese PJ, Resnick SM, Conover JC. Ventricular and Periventricular Anomalies in the Aging and Cognitively Impaired Brain. Frontiers in Aging Neuroscience. 9: 445. PMID 29379433 DOI: 10.3389/fnagi.2017.00445  0.4
2017 Kim H, Ham S, Lee JY, Jo A, Lee GH, Lee YS, Cho M, Shin HM, Kim D, Pletnikova O, Troncoso JC, Shin JH, Lee YI, Lee Y. Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models. Oncotarget. 8: 106721-106739. PMID 29290984 DOI: 10.18632/oncotarget.21828  0.4
2017 Chiang ACA, Fowler SW, Reddy R, Pletnikova O, Troncoso JC, Sherman MA, Lesne SE, Jankowsky JL. Discrete pools of oligomeric amyloid-β track with spatial learning deficits in a mouse model of Alzheimer amyloidosis. The American Journal of Pathology. PMID 29248459 DOI: 10.1016/j.ajpath.2017.11.011  0.4
2017 Na CH, Barbhuiya M, Kim MS, Verbruggen S, Eacker S, Pletnikova O, Troncoso J, Halushka M, Menschaert G, Overall C, Pandey A. Discovery of non-canonical translation initiation sites through mass spectrometric analysis of protein N-termini. Genome Research. PMID 29162641 DOI: 10.1101/gr.226050.117  0.4
2017 Hinkle JT, Perepezko K, Bakker CC, Dawson TM, Johnson V, Mari Z, Marvel CL, Mills KA, Pantelyat A, Pletnikova O, Rosenthal LS, Shepard MD, Stevens DA, Troncoso JC, Wang J, et al. Domain-specific cognitive impairment in non-demented Parkinson's disease psychosis. International Journal of Geriatric Psychiatry. PMID 28509347 DOI: 10.1002/gps.4736  0.4
2017 Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, ... ... Troncoso JC, et al. NPTX2 and cognitive dysfunction in Alzheimer's Disease. Elife. 6. PMID 28440221 DOI: 10.7554/eLife.23798  0.52
2017 Grima JC, Daigle JG, Arbez N, Cunningham KC, Zhang K, Ochaba J, Geater C, Morozko E, Stocksdale J, Glatzer JC, Pham JT, Ahmed I, Peng Q, Wadhwa H, Pletnikova O, ... Troncoso JC, et al. Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 94: 93-107.e6. PMID 28384479 DOI: 10.1016/j.neuron.2017.03.023  0.4
2017 Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL. Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43. Acta Neuropathologica. PMID 28332094 DOI: 10.1007/s00401-017-1701-2  0.56
2016 Blauwendraat C, Nalls MA, Federoff M, Pletnikova O, Ding J, Letson C, Geiger JT, Gibbs JR, Hernandez DG, Troncoso JC, Simón-Sánchez J, Scholz SW. ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27987235 DOI: 10.1002/mds.26886  0.4
2016 Mills KA, Mari Z, Bakker C, Johnson V, Pontone GM, Pantelyat A, Troncoso JC, Pletnikova O, Dawson TM, Rosenthal LS. Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients. Parkinsonism & Related Disorders. PMID 27693194 DOI: 10.1016/j.parkreldis.2016.09.024  0.4
2016 Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM. Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons. Eneuro. 3. PMID 27622213 DOI: 10.1523/ENEURO.0183-16.2016  0.4
2016 Ratovitski T, Chaerkady R, Kammers K, Stewart JC, Zavala A, Pletnikova O, Troncoso JC, Rudnicki DD, Margolis RL, Cole RN, Ross CA. Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains. Journal of Proteome Research. PMID 27486686 DOI: 10.1021/acs.jproteome.6b00448  0.4
2016 Brahmachari S, Ge P, Lee SH, Kim D, Karuppagounder SS, Kumar M, Mao X, Lee Y, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Ko HS. Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration. The Journal of Clinical Investigation. PMID 27348587 DOI: 10.1172/JCI85456  0.84
2016 Geiger JT, Ding J, Crain B, Pletnikova O, Letson C, Dawson TM, Rosenthal LS, Pantelyat A, Gibbs JR, Albert MS, Hernandez DG, Hillis AE, Stone DJ, Singleton AB, ... ... Troncoso JC, et al. Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies. Neurobiology of Disease. PMID 27312774 DOI: 10.1016/j.nbd.2016.06.004  0.84
2016 Nucifora FC, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, et al. Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. Nature Communications. 7: 11792. PMID 27273569 DOI: 10.1038/ncomms11792  0.84
2016 Tabbarah AZ, Robert Bell W, Sun M, Gelwan E, Pletnikova O, Hillis AE, Troncoso JC, Lin MT, Chen L. A rapidly progressive dementia case with pathological diagnosis of FTLD-UPS. Acta Neuropathologica. PMID 27271575 DOI: 10.1007/s00401-016-1584-7  0.4
2016 Henderson BW, Gentry EG, Rush T, Troncoso JC, Thambisetty M, Montine TJ, Herskowitz JH. Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain. Journal of Neurochemistry. PMID 27246255 DOI: 10.1111/jnc.13688  0.84
2016 Geiger JT, Arthur KC, Dawson TM, Rosenthal LS, Pantelyat A, Albert M, Hillis AE, Crain B, Pletnikova O, Troncoso JC, Scholz SW. C9orf72 Hexanucleotide Repeat Analysis in Cases with Pathologically Confirmed Dementia with Lewy Bodies. Neuro-Degenerative Diseases. 16: 370-372. PMID 27241037 DOI: 10.1159/000445872  0.4
2016 Grimm JC, Magruder JT, Wilson MA, Blue ME, Crawford TC, Troncoso JC, Zhang F, Kannan S, Sciortino CM, Johnston MV, Kannan RM, Baumgartner WA. Nanotechnology Approaches to Targeting Inflammation and Excitotoxicity in a Canine Model of Hypothermic Circulatory Arrest-Induced Brain Injury. The Annals of Thoracic Surgery. PMID 27154161 DOI: 10.1016/j.athoracsur.2016.02.077  0.84
2015 Choi S, Kim D, Kam TI, Yun S, Kim S, Park H, Hwang H, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Ko HS. Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity. Plos One. 10: e0143854. PMID 26629917 DOI: 10.1371/journal.pone.0143854  0.4
2015 Bañez-Coronel M, Ayhan F, Tarabochia AD, Zu T, Perez BA, Tusi SK, Pletnikova O, Borchelt DR, Ross CA, Margolis RL, Yachnis AT, Troncoso JC, Ranum LP. RAN Translation in Huntington Disease. Neuron. 88: 667-77. PMID 26590344 DOI: 10.1016/j.neuron.2015.10.038  0.8
2015 Pletnikova O, Rudow GL, Hyde TM, Kleinman JE, Ali SZ, Bharadwaj R, Gangadeen S, Crain BJ, Fowler DR, Rubio AI, Troncoso JC. Alzheimer Lesions in the Autopsied Brains of People 30 to 50 Years of Age. Cognitive and Behavioral Neurology : Official Journal of the Society For Behavioral and Cognitive Neurology. 28: 144-52. PMID 26413742 DOI: 10.1097/WNN.0000000000000071  0.84
2015 O'Hearn EE, Hwang HS, Holmes SE, Rudnicki DD, Chung DW, Seixas AI, Cohen RL, Ross CA, Trojanowski JQ, Pletnikova O, Troncoso JC, Margolis RL. Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26340331 DOI: 10.1002/mds.26348  0.84
2015 Chuang YF, An Y, Bilgel M, Wong DF, Troncoso JC, O'Brien RJ, Breitner JC, Ferruci L, Resnick SM, Thambisetty M. Midlife adiposity predicts earlier onset of Alzheimer's dementia, neuropathology and presymptomatic cerebral amyloid accumulation. Molecular Psychiatry. PMID 26324099 DOI: 10.1038/mp.2015.129  0.36
2015 Ling JP, Pletnikova O, Troncoso JC, Wong PC. NEURODEGENERATION. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science (New York, N.Y.). 349: 650-5. PMID 26250685 DOI: 10.1126/science.aab0983  0.56
2015 Iacono D, Zandi P, Gross M, Markesbery WR, Pletnikova O, Rudow G, Troncoso JC. APOε2 and education in cognitively normal older subjects with high levels of AD pathology at autopsy: findings from the Nun Study. Oncotarget. 6: 14082-91. PMID 26101858  0.84
2015 Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, ... ... Troncoso JC, et al. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathologica. 129: 757-62. PMID 25778618 DOI: 10.1007/s00401-015-1407-2  0.84
2015 Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, et al. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Neurology. 84: 972-80. PMID 25663231 DOI: 10.1212/WNL.0000000000001332  0.84
2015 Aggarwal M, Nauen DW, Troncoso JC, Mori S. Probing region-specific microstructure of human cortical areas using high angular and spatial resolution diffusion MRI. Neuroimage. 105: 198-207. PMID 25449747 DOI: 10.1016/j.neuroimage.2014.10.053  0.84
2014 Ryu J, Horkayne-Szakaly I, Xu L, Pletnikova O, Leri F, Eberhart C, Troncoso JC, Koliatsos VE. The problem of axonal injury in the brains of veterans with histories of blast exposure. Acta Neuropathologica Communications. 2: 153. PMID 25422066 DOI: 10.1186/s40478-014-0153-3  0.4
2014 Blue ME, Wilson MA, Beaty CA, George TJ, Arnaoutakis GJ, Haggerty KA, Jones M, Brawn J, Manmohan S, Lange MS, Johnston MV, Baumgartner WA, Troncoso JC. Brain injury in canine models of cardiac surgery. Journal of Neuropathology and Experimental Neurology. 73: 1134-43. PMID 25383634 DOI: 10.1097/NEN.0000000000000134  0.84
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, ... ... Troncoso JC, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/s00401-014-1349-0  0.84
2014 Farinelli PA, Padin JM, Troncoso JC, Bertolotti A, Lenz M, Sanchez N, Fortunato R, Caravello E, Imperiali N, Dip M, Sanchez Claria R, Arriola M, De Arteaga J, Pujol Soler G, Bisigniano L, et al. Short- and long-term outcomes of every graft recovered during a multi-organ procurement procedure including the intestine. Transplantation Proceedings. 46: 2090-5. PMID 25131114 DOI: 10.1016/j.transproceed.2014.06.040  0.84
2014 Ali Z, Troncoso JC, Fowler DR. Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature. Forensic Science International. 242: e52-5. PMID 25074331 DOI: 10.1016/j.forsciint.2014.07.007  0.84
2014 Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathologica Communications. 2: 56. PMID 24887264 DOI: 10.1186/2051-5960-2-56  0.84
2014 Ayers JI, Xu G, Pletnikova O, Troncoso JC, Hart PJ, Borchelt DR. Conformational specificity of the C4F6 SOD1 antibody; low frequency of reactivity in sporadic ALS cases. Acta Neuropathologica Communications. 2: 55. PMID 24887207 DOI: 10.1186/2051-5960-2-55  0.84
2014 Liu G, Yu J, Ding J, Xie C, Sun L, Rudenko I, Zheng W, Sastry N, Luo J, Rudow G, Troncoso JC, Cai H. Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation. The Journal of Clinical Investigation. 124: 3032-46. PMID 24865427 DOI: 10.1172/JCI72176  0.84
2014 Kang MJ, Abdelmohsen K, Hutchison ER, Mitchell SJ, Grammatikakis I, Guo R, Noh JH, Martindale JL, Yang X, Lee EK, Faghihi MA, Wahlestedt C, Troncoso JC, Pletnikova O, Perrone-Bizzozero N, et al. HuD regulates coding and noncoding RNA to induce APP→Aβ processing. Cell Reports. 7: 1401-9. PMID 24857657 DOI: 10.1016/j.celrep.2014.04.050  0.84
2014 Pletnikova O, Sloane KL, Renton AE, Traynor BJ, Crain BJ, Reid T, Zu T, Ranum LP, Troncoso JC, Rabins PV, Onyike CU. Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion. Neurobiology of Aging. 35: 2419.e17-21. PMID 24819148 DOI: 10.1016/j.neurobiolaging.2014.04.009  0.84
2014 Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Molecular Neurodegeneration. 9: 15. PMID 24773620 DOI: 10.1186/1750-1326-9-15  0.84
2014 Tsika E, Glauser L, Moser R, Fiser A, Daniel G, Sheerin UM, Lees A, Troncoso JC, Lewis PA, Bandopadhyay R, Schneider BL, Moore DJ. Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration. Human Molecular Genetics. 23: 4621-38. PMID 24740878 DOI: 10.1093/hmg/ddu178  0.84
2014 Iacono D, Resnick SM, O'Brien R, Zonderman AB, An Y, Pletnikova O, Rudow G, Crain B, Troncoso JC. Mild cognitive impairment and asymptomatic Alzheimer disease subjects: equivalent β-amyloid and tau loads with divergent cognitive outcomes. Journal of Neuropathology and Experimental Neurology. 73: 295-304. PMID 24607960 DOI: 10.1097/NEN.0000000000000052  0.84
2014 Haeusler AR, Donnelly CJ, Periz G, Simko EA, Shaw PG, Kim MS, Maragakis NJ, Troncoso JC, Pandey A, Sattler R, Rothstein JD, Wang J. C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200. PMID 24598541 DOI: 10.1038/nature13124  0.84
2014 Mishra MK, Beaty CA, Lesniak WG, Kambhampati SP, Zhang F, Wilson MA, Blue ME, Troncoso JC, Kannan S, Johnston MV, Baumgartner WA, Kannan RM. Dendrimer brain uptake and targeted therapy for brain injury in a large animal model of hypothermic circulatory arrest. Acs Nano. 8: 2134-47. PMID 24499315 DOI: 10.1021/nn404872e  0.84
2013 Onyike CU, Pletnikova O, Sloane KL, Sullivan C, Troncoso JC, Rabins PV. Hippocampal sclerosis dementia: An amnesic variant of frontotemporal degeneration. Dementia & Neuropsychologia. 7: 83-87. PMID 24363834  0.4
2013 Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ. Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19086-98. PMID 24305806 DOI: 10.1523/JNEUROSCI.2508-13.2013  0.84
2013 Zu T, Liu Y, Bañez-Coronel M, Reid T, Pletnikova O, Lewis J, Miller TM, Harms MB, Falchook AE, Subramony SH, Ostrow LW, Rothstein JD, Troncoso JC, Ranum LP. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. 110: E4968-77. PMID 24248382 DOI: 10.1073/pnas.1315438110  0.84
2013 Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. Journal of Neuropathology and Experimental Neurology. 72: 1009-15. PMID 24128675 DOI: 10.1097/01.jnen.0000435847.59828.db  0.84
2013 Thambisetty M, Jeffrey Metter E, Yang A, Dolan H, Marano C, Zonderman AB, Troncoso JC, Zhou Y, Wong DF, Ferrucci L, Egan J, Resnick SM, O'Brien RJ. Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging. Jama Neurology. 70: 1167-72. PMID 23897112 DOI: 10.1001/jamaneurol.2013.284  0.84
2013 LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice. Molecular Neurodegeneration. 8: 18. PMID 23764200 DOI: 10.1186/1750-1326-8-18  0.84
2013 Riudavets MA, Bartoloni L, Troncoso JC, Pletnikova O, St George-Hyslop P, Schultz M, Sevlever G, Allegri RF. Familial dementia with frontotemporal features associated with M146V presenilin-1 mutation. Brain Pathology (Zurich, Switzerland). 23: 595-600. PMID 23489366 DOI: 10.1111/bpa.12051  0.4
2013 Jin J, Albertz J, Guo Z, Peng Q, Rudow G, Troncoso JC, Ross CA, Duan W. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease. Journal of Neurochemistry. 125: 410-9. PMID 23373812 DOI: 10.1111/jnc.12190  0.84
2013 Cho HJ, Liu G, Jin SM, Parisiadou L, Xie C, Yu J, Sun L, Ma B, Ding J, Vancraenenbroeck R, Lobbestael E, Baekelandt V, Taymans JM, He P, Troncoso JC, et al. MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein. Human Molecular Genetics. 22: 608-20. PMID 23125283 DOI: 10.1093/hmg/dds470  0.84
2013 Terracciano A, Iacono D, O'Brien RJ, Troncoso JC, An Y, Sutin AR, Ferrucci L, Zonderman AB, Resnick SM. Personality and resilience to Alzheimer's disease neuropathology: a prospective autopsy study. Neurobiology of Aging. 34: 1045-50. PMID 23040035 DOI: 10.1016/j.neurobiolaging.2012.08.008  0.84
2012 Guo Z, Rudow G, Pletnikova O, Codispoti KE, Orr BA, Crain BJ, Duan W, Margolis RL, Rosenblatt A, Ross CA, Troncoso JC. Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1379-86. PMID 22975850 DOI: 10.1002/mds.25159  0.84
2012 Driscoll I, Troncoso JC, Rudow G, Sojkova J, Pletnikova O, Zhou Y, Kraut MA, Ferrucci L, Mathis CA, Klunk WE, O'Brien RJ, Davatzikos C, Wong DF, Resnick SM. Correspondence between in vivo (11)C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques. Acta Neuropathologica. 124: 823-31. PMID 22864813 DOI: 10.1007/s00401-012-1025-1  0.84
2012 Codispoti KE, Beason-Held LL, Kraut MA, O'Brien RJ, Rudow G, Pletnikova O, Crain B, Troncoso JC, Resnick SM. Longitudinal brain activity changes in asymptomatic Alzheimer disease. Brain and Behavior. 2: 221-30. PMID 22741095 DOI: 10.1002/brb3.47  0.84
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Troncoso JC, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/hmg/dds161  0.84
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, ... ... Troncoso JC, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/NEN.0b013e31825018f7  0.84
2012 Colla E, Coune P, Liu Y, Pletnikova O, Troncoso JC, Iwatsubo T, Schneider BL, Lee MK. Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3306-20. PMID 22399753 DOI: 10.1523/JNEUROSCI.5367-11.2012  0.84
2012 Colla E, Jensen PH, Pletnikova O, Troncoso JC, Glabe C, Lee MK. Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3301-5. PMID 22399752 DOI: 10.1523/JNEUROSCI.5368-11.2012  0.84
2012 Daher JP, Pletnikova O, Biskup S, Musso A, Gellhaar S, Galter D, Troncoso JC, Lee MK, Dawson TM, Dawson VL, Moore DJ. Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2. Human Molecular Genetics. 21: 2420-31. PMID 22357653 DOI: 10.1093/hmg/dds057  0.84
2012 Majounie E, Abramzon Y, Renton AE, Perry R, Bassett SS, Pletnikova O, Troncoso JC, Hardy J, Singleton AB, Traynor BJ. Repeat expansion in C9ORF72 in Alzheimer's disease. The New England Journal of Medicine. 366: 283-4. PMID 22216764 DOI: 10.1056/NEJMc1113592  0.84
2012 Ramonet D, Podhajska A, Stafa K, Sonnay S, Trancikova A, Tsika E, Pletnikova O, Troncoso JC, Glauser L, Moore DJ. PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Human Molecular Genetics. 21: 1725-43. PMID 22186024 DOI: 10.1093/hmg/ddr606  0.4
2012 Savonenko AV, Melnikova T, Hiatt A, Li T, Worley PF, Troncoso JC, Wong PC, Price DL. Alzheimer's therapeutics: translation of preclinical science to clinical drug development. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 261-77. PMID 21937983 DOI: 10.1038/npp.2011.211  0.84
2012 Gleichmann M, Zhang Y, Wood WH, Becker KG, Mughal MR, Pazin MJ, van Praag H, Kobilo T, Zonderman AB, Troncoso JC, Markesbery WR, Mattson MP. Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks. Neurobiology of Aging. 33: 205.e1-18. PMID 20947216 DOI: 10.1016/j.neurobiolaging.2010.08.012  0.84
2011 Airavaara M, Pletnikova O, Doyle ME, Zhang YE, Troncoso JC, Liu QR. Identification of novel GDNF isoforms and cis-antisense GDNFOS gene and their regulation in human middle temporal gyrus of Alzheimer disease. The Journal of Biological Chemistry. 286: 45093-102. PMID 22081608 DOI: 10.1074/jbc.M111.310250  0.84
2011 Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, et al. Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation. Cell. 147: 615-28. PMID 22036569 DOI: 10.1016/j.cell.2011.09.036  0.84
2011 Arnaoutakis GJ, George TJ, Wang KK, Wilson MA, Allen JG, Robinson CW, Haggerty KA, Weiss ES, Blue ME, Talbot CC, Troncoso JC, Johnston MV, Baumgartner WA. Serum levels of neuron-specific ubiquitin carboxyl-terminal esterase-L1 predict brain injury in a canine model of hypothermic circulatory arrest. The Journal of Thoracic and Cardiovascular Surgery. 142: 902-910.e1. PMID 21924148 DOI: 10.1016/j.jtcvs.2011.06.027  0.84
2011 Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, et al. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. Plos One. 6: e18568. PMID 21494637 DOI: 10.1371/journal.pone.0018568  0.84
2011 Sojkova J, Driscoll I, Iacono D, Zhou Y, Codispoti KE, Kraut MA, Ferrucci L, Pletnikova O, Mathis CA, Klunk WE, O'Brien RJ, Wong DF, Troncoso JC, Resnick SM. In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults. Archives of Neurology. 68: 232-40. PMID 21320990 DOI: 10.1001/archneurol.2010.357  0.84
2011 Liu Y, Lee MK, James MM, Price DL, Borchelt DR, Troncoso JC, Oh ES. Passive (amyloid-β) immunotherapy attenuates monoaminergic axonal degeneration in the AβPPswe/PS1dE9 mice. Journal of Alzheimer's Disease : Jad. 23: 271-9. PMID 20966549 DOI: 10.3233/JAD-2010-101602  0.84
2011 Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, et al. Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiology of Aging. 32: 2113-22. PMID 20452100 DOI: 10.1016/j.neurobiolaging.2010.01.010  0.84
2010 Ko HS, Lee Y, Shin JH, Karuppagounder SS, Gadad BS, Koleske AJ, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM. Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. Proceedings of the National Academy of Sciences of the United States of America. 107: 16691-6. PMID 20823226 DOI: 10.1073/pnas.1006083107  0.84
2010 Chiocco MJ, Zhu X, Walther D, Pletnikova O, Troncoso JC, Uhl GR, Liu QR. Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease. Substance Use & Misuse. 45: 1809-26. PMID 20590401 DOI: 10.3109/10826084.2010.482449  0.84
2010 Allen JG, Weiss ES, Wilson MA, Arnaoutakis GJ, Blue ME, Talbot CC, Jie C, Lange MS, Troncoso JC, Johnston MV, Baumgartner WA. Hawley H. Seiler Resident Award. Transcriptional profile of brain injury in hypothermic circulatory arrest and cardiopulmonary bypass. The Annals of Thoracic Surgery. 89: 1965-71. PMID 20494057 DOI: 10.1016/j.athoracsur.2010.02.051  0.84
2010 Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. Human Molecular Genetics. 19: 2087-98. PMID 20185556 DOI: 10.1093/hmg/ddq086  0.84
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Troncoso JC, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/ng.536  0.84
2010 Tseng EE, Brock MV, Lange MS, Troncoso JC, Blue ME, Lowenstein CJ, Johnston MV, Baumgartner WA. Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 89: 440-5. PMID 20103318 DOI: 10.1016/j.athoracsur.2009.10.059  0.84
2010 Dorfman VB, Pasquini L, Riudavets M, López-Costa JJ, Villegas A, Troncoso JC, Lopera F, Castaño EM, Morelli L. Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease. Neurobiology of Aging. 31: 1743-57. PMID 19019493 DOI: 10.1016/j.neurobiolaging.2008.09.016  0.84
2009 Lin X, Parisiadou L, Gu XL, Wang L, Shim H, Sun L, Xie C, Long CX, Yang WJ, Ding J, Chen ZZ, Gallant PE, Tao-Cheng JH, Rudow G, Troncoso JC, et al. Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron. 64: 807-27. PMID 20064389 DOI: 10.1016/j.neuron.2009.11.006  0.84
2009 O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L, Crain BJ, Pletnikova O, Rudow G, Iacono D, Riudavets MA, Driscoll I, Price DL, Martin LJ, Troncoso JC. Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA). Journal of Alzheimer's Disease : Jad. 18: 665-75. PMID 19661626 DOI: 10.3233/JAD-2009-1179  0.84
2009 Weiss ES, Wang KK, Allen JG, Blue ME, Nwakanma LU, Liu MC, Lange MS, Berrong J, Wilson MA, Gott VL, Troncoso JC, Hayes RL, Johnston MV, Baumgartner WA. Alpha II-spectrin breakdown products serve as novel markers of brain injury severity in a canine model of hypothermic circulatory arrest. The Annals of Thoracic Surgery. 88: 543-50. PMID 19632410 DOI: 10.1016/j.athoracsur.2009.04.016  0.84
2009 Iacono D, Markesbery WR, Gross M, Pletnikova O, Rudow G, Zandi P, Troncoso JC. The Nun study: clinically silent AD, neuronal hypertrophy, and linguistic skills in early life. Neurology. 73: 665-73. PMID 19587326 DOI: 10.1212/WNL.0b013e3181b01077  0.84
2009 Tsang AH, Lee YI, Ko HS, Savitt JM, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Chung KK. S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 4900-5. PMID 19273858 DOI: 10.1073/pnas.0810595106  0.84
2009 Oh ES, Savonenko AV, King JF, Fangmark Tucker SM, Rudow GL, Xu G, Borchelt DR, Troncoso JC. Amyloid precursor protein increases cortical neuron size in transgenic mice. Neurobiology of Aging. 30: 1238-44. PMID 18304698 DOI: 10.1016/j.neurobiolaging.2007.12.024  0.8
2008 Oh ES, Troncoso JC, Fangmark Tucker SM. Maximizing the potential of plasma amyloid-beta as a diagnostic biomarker for Alzheimer's disease. Neuromolecular Medicine. 10: 195-207. PMID 18543125 DOI: 10.1007/s12017-008-8035-0  0.52
2008 Iacono D, O'Brien R, Resnick SM, Zonderman AB, Pletnikova O, Rudow G, An Y, West MJ, Crain B, Troncoso JC. Neuronal hypertrophy in asymptomatic Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 67: 578-89. PMID 18520776 DOI: 10.1097/NEN.0b013e3181772794  0.84
2008 Troncoso JC, Zonderman AB, Resnick SM, Crain B, Pletnikova O, O'Brien RJ. Effect of infarcts on dementia in the Baltimore longitudinal study of aging. Annals of Neurology. 64: 168-76. PMID 18496870 DOI: 10.1002/ana.21413  0.84
2008 Rudow G, O'Brien R, Savonenko AV, Resnick SM, Zonderman AB, Pletnikova O, Marsh L, Dawson TM, Crain BJ, West MJ, Troncoso JC. Morphometry of the human substantia nigra in ageing and Parkinson's disease. Acta Neuropathologica. 115: 461-70. PMID 18297291 DOI: 10.1007/s00401-008-0352-8  0.84
2008 Tucker SM, Borchelt DR, Troncoso JC. Limited clearance of pre-existing amyloid plaques after intracerebral injection of Abeta antibodies in two mouse models of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 67: 30-40. PMID 18091561 DOI: 10.1097/nen.0b013e31815f38d2  0.84
2007 Morgan MD, Mielke MM, O'Brien R, Troncoso JC, Zonderman AB, Lyketsos CG. Rates of depression in individuals with pathologic but not clinical Alzheimer disease are lower than those in individuals without the disease: findings from the Baltimore Longitudinal Study on Aging (BLSA). Alzheimer Disease and Associated Disorders. 21: 199-204. PMID 17804951 DOI: 10.1097/WAD.0b013e3181461932  0.84
2007 Hishimoto A, Liu QR, Drgon T, Pletnikova O, Walther D, Zhu XG, Troncoso JC, Uhl GR. Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms. Human Molecular Genetics. 16: 2880-91. PMID 17804423 DOI: 10.1093/hmg/ddm247  0.84
2007 Riudavets MA, Iacono D, Resnick SM, O'Brien R, Zonderman AB, Martin LJ, Rudow G, Pletnikova O, Troncoso JC. Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons. Neurobiology of Aging. 28: 1484-92. PMID 17599696 DOI: 10.1016/j.neurobiolaging.2007.05.005  0.84
2007 Spina S, Murrell JR, Huey ED, Wassermann EM, Pietrini P, Baraibar MA, Barbeito AG, Troncoso JC, Vidal R, Ghetti B, Grafman J. Clinicopathologic features of frontotemporal dementia with progranulin sequence variation. Neurology. 68: 820-7. PMID 17202431 DOI: 10.1212/01.wnl.0000254460.31273.2d  0.84
2006 Driscoll I, Resnick SM, Troncoso JC, An Y, O'Brien R, Zonderman AB. Impact of Alzheimer's pathology on cognitive trajectories in nondemented elderly. Annals of Neurology. 60: 688-95. PMID 17192929 DOI: 10.1002/ana.21031  0.84
2006 Riudavets MA, Rubio A, Cox C, Rudow G, Fowler D, Troncoso JC. The prevalence of Alzheimer neuropathologic lesions is similar in blacks and whites. Journal of Neuropathology and Experimental Neurology. 65: 1143-8. PMID 17146288 DOI: 10.1097/01.jnen.0000248548.20799.a3  0.8
2006 Zamora E, Handisurya A, Shafti-Keramat S, Borchelt D, Rudow G, Conant K, Cox C, Troncoso JC, Kirnbauer R. Papillomavirus-like particles are an effective platform for amyloid-beta immunization in rabbits and transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 2662-70. PMID 16888028  0.84
2006 Koliatsos VE, Kecojevic A, Troncoso JC, Gastard MC, Bennett DA, Schneider JA. Early involvement of small inhibitory cortical interneurons in Alzheimer's disease. Acta Neuropathologica. 112: 147-62. PMID 16758165 DOI: 10.1007/s00401-006-0068-6  0.84
2006 Williams JA, Barreiro CJ, Nwakanma LU, Lange MS, Kratz LE, Blue ME, Berrong J, Patel ND, Gott VL, Troncoso JC, Johnston MV, Baumgartner WA. Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery. The Annals of Thoracic Surgery. 81: 2235-41; discussion . PMID 16731160 DOI: 10.1016/j.athoracsur.2005.12.060  0.84
2006 Bäckman CM, Shan L, Zhang YJ, Hoffer BJ, Leonard S, Troncoso JC, Vonsatel P, Tomac AC. Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study. Molecular and Cellular Endocrinology. 252: 160-6. PMID 16644101 DOI: 10.1016/j.mce.2006.03.013  0.84
2006 Barreiro CJ, Williams JA, Fitton TP, Lange MS, Blue ME, Kratz L, Barker PB, Degaonkar M, Gott VL, Troncoso JC, Johnston MV, Baumgartner WA. Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy. The Annals of Thoracic Surgery. 81: 1593-8. PMID 16631640 DOI: 10.1016/j.athoracsur.2006.01.011  0.84
2005 Stoltenberg M, Bruhn M, Søndergaard C, Doering P, West MJ, Larsen A, Troncoso JC, Danscher G. Immersion autometallographic tracing of zinc ions in Alzheimer beta-amyloid plaques. Histochemistry and Cell Biology. 123: 605-11. PMID 15981003 DOI: 10.1007/s00418-005-0787-0  0.84
2005 Smith WW, Margolis RL, Li X, Troncoso JC, Lee MK, Dawson VL, Dawson TM, Iwatsubo T, Ross CA. Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5544-52. PMID 15944382 DOI: 10.1523/JNEUROSCI.0482-05.2005  0.84
2005 Pletnikova O, West N, Lee MK, Rudow GL, Skolasky RL, Dawson TM, Marsh L, Troncoso JC. Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases. Neurobiology of Aging. 26: 1183-92. PMID 15917102 DOI: 10.1016/j.neurobiolaging.2004.10.006  0.84
2005 Mikolaenko I, Pletnikova O, Kawas CH, O'Brien R, Resnick SM, Crain B, Troncoso JC. Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA). Journal of Neuropathology and Experimental Neurology. 64: 156-62. PMID 15751230  0.84
2005 Li W, West N, Colla E, Pletnikova O, Troncoso JC, Marsh L, Dawson TM, Jäkälä P, Hartmann T, Price DL, Lee MK. Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations. Proceedings of the National Academy of Sciences of the United States of America. 102: 2162-7. PMID 15684072 DOI: 10.1073/pnas.0406976102  0.84
2004 Li W, Lesuisse C, Xu Y, Troncoso JC, Price DL, Lee MK. Stabilization of alpha-synuclein protein with aging and familial parkinson's disease-linked A53T mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7400-9. PMID 15317865 DOI: 10.1523/JNEUROSCI.1370-04.2004  0.84
2004 West MJ, Kawas CH, Stewart WF, Rudow GL, Troncoso JC. Hippocampal neurons in pre-clinical Alzheimer's disease. Neurobiology of Aging. 25: 1205-12. PMID 15312966 DOI: 10.1016/j.neurobiolaging.2003.12.005  0.84
2004 Hatanpaa KJ, Blass DM, Pletnikova O, Crain BJ, Bigio EH, Hedreen JC, White CL, Troncoso JC. Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia. Neurology. 63: 538-42. PMID 15304590  0.84
2004 Mitchelmore C, Büchmann-Møller S, Rask L, West MJ, Troncoso JC, Jensen NA. NDRG2: a novel Alzheimer's disease associated protein. Neurobiology of Disease. 16: 48-58. PMID 15207261 DOI: 10.1016/j.nbd.2004.01.003  0.84
2004 Chung KK, Thomas B, Li X, Pletnikova O, Troncoso JC, Marsh L, Dawson VL, Dawson TM. S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science (New York, N.Y.). 304: 1328-31. PMID 15105460 DOI: 10.1126/science.1093891  0.84
2004 Zainelli GM, Ross CA, Troncoso JC, Fitzgerald JK, Muma NA. Calmodulin regulates transglutaminase 2 cross-linking of huntingtin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1954-61. PMID 14985437 DOI: 10.1523/JNEUROSCI.4424-03.2004  0.84
2004 Fonseca MI, Kawas CH, Troncoso JC, Tenner AJ. Neuronal localization of C1q in preclinical Alzheimer's disease. Neurobiology of Disease. 15: 40-6. PMID 14751769 DOI: 10.1016/j.nbd.2003.09.004  0.84
2003 Rosenblatt A, Abbott MH, Gourley LM, Troncoso JC, Margolis RL, Brandt J, Ross CA. Predictors of neuropathological severity in 100 patients with Huntington's disease. Annals of Neurology. 54: 488-93. PMID 14520661 DOI: 10.1002/ana.10691  0.84
2003 Gastard MC, Troncoso JC, Koliatsos VE. Caspase activation in the limbic cortex of subjects with early Alzheimer's disease. Annals of Neurology. 54: 393-8. PMID 12953274 DOI: 10.1002/ana.10680  0.84
2003 Zemaitaitis MO, Kim SY, Halverson RA, Troncoso JC, Lee JM, Muma NA. Transglutaminase activity, protein, and mRNA expression are increased in progressive supranuclear palsy. Journal of Neuropathology and Experimental Neurology. 62: 173-84. PMID 12578227  0.84
2003 Zainelli GM, Ross CA, Troncoso JC, Muma NA. Transglutaminase cross-links in intranuclear inclusions in Huntington disease. Journal of Neuropathology and Experimental Neurology. 62: 14-24. PMID 12528814  0.84
2003 Vehmas AK, Kawas CH, Stewart WF, Troncoso JC. Immune reactive cells in senile plaques and cognitive decline in Alzheimer's disease. Neurobiology of Aging. 24: 321-31. PMID 12498966  0.8
2001 Shake JG, Peck EA, Marban E, Gott VL, Johnston MV, Troncoso JC, Redmond JM, Baumgartner WA. Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection. The Annals of Thoracic Surgery. 72: 1849-54. PMID 11789759 DOI: 10.1016/S0003-4975(01)03192-7  0.84
2001 Vehmas AK, Borchelt DR, Price DL, McCarthy D, Wills-Karp M, Peper MJ, Rudow G, Luyinbazi J, Siew LT, Troncoso JC. beta-Amyloid peptide vaccination results in marked changes in serum and brain Abeta levels in APPswe/PS1DeltaE9 mice, as detected by SELDI-TOF-based ProteinChip technology. Dna and Cell Biology. 20: 713-21. PMID 11788049 DOI: 10.1089/10445490152717578  0.84
2001 Margolis RL, O'Hearn E, Rosenblatt A, Willour V, Holmes SE, Franz ML, Callahan C, Hwang HS, Troncoso JC, Ross CA. A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion. Annals of Neurology. 50: 373-80. PMID 11558794 DOI: 10.1002/ana.1124  0.84
2001 Gyure KA, Durham R, Stewart WF, Smialek JE, Troncoso JC. Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Archives of Pathology & Laboratory Medicine. 125: 489-92. PMID 11260621 DOI: 10.1043/0003-9985(2001)125<0489:IAAPDO>2.0.CO;2  0.84
2000 Zemaitaitis MO, Lee JM, Troncoso JC, Muma NA. Transglutaminase-induced cross-linking of tau proteins in progressive supranuclear palsy. Journal of Neuropathology and Experimental Neurology. 59: 983-9. PMID 11089576  0.84
2000 Kang DE, Pietrzik CU, Baum L, Chevallier N, Merriam DE, Kounnas MZ, Wagner SL, Troncoso JC, Kawas CH, Katzman R, Koo EH. Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway. The Journal of Clinical Investigation. 106: 1159-66. PMID 11067868 DOI: 10.1172/JCI11013  0.84
2000 West MJ, Kawas CH, Martin LJ, Troncoso JC. The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease. Annals of the New York Academy of Sciences. 908: 255-9. PMID 10911964  0.84
2000 Cataldo AM, Peterhoff CM, Troncoso JC, Gomez-Isla T, Hyman BT, Nixon RA. Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations. The American Journal of Pathology. 157: 277-86. PMID 10880397  0.84
1999 Chambers CB, Lee JM, Troncoso JC, Reich S, Muma NA. Overexpression of four-repeat tau mRNA isoforms in progressive supranuclear palsy but not in Alzheimer's disease. Annals of Neurology. 46: 325-32. PMID 10482263 DOI: 10.1002/1531-8249(199909)46:3<325::AID-ANA8>3.0.CO;2-V  0.84
1999 Baumgartner WA, Walinsky PL, Salazar JD, Tseng EE, Brock MV, Doty JR, Redmond JM, Blue ME, Goldsborough MA, Troncoso JC, Johnston MV. Assessing the impact of cerebral injury after cardiac surgery: will determining the mechanism reduce this injury? The Annals of Thoracic Surgery. 67: 1871-3; discussion 1. PMID 10391329 DOI: 10.1016/S0003-4975(99)00445-2  0.84
1999 Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nature Genetics. 22: 110-4. PMID 10319874 DOI: 10.1038/8820  0.84
1999 Tseng EE, Brock MV, Kwon CC, Annanata M, Lange MS, Troncoso JC, Johnston MV, Baumgartner WA. Increased intracerebral excitatory amino acids and nitric oxide after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 67: 371-6. PMID 10197655 DOI: 10.1016/S0003-4975(99)00033-8  0.84
1999 Tseng EE, Brock MV, Lange MS, Troncoso JC, Lowenstein CJ, Blue ME, Johnston MV, Baumgartner WA. Nitric oxide mediates neurologic injury after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 67: 65-71. PMID 10086526 DOI: 10.1016/S0003-4975(98)01363-0  0.84
1998 Morrison AL, Chute D, Radentz S, Golle M, Troncoso JC, Smialek JE. Air bag-associated injury to a child in the front passenger seat. The American Journal of Forensic Medicine and Pathology. 19: 218-22. PMID 9760084 DOI: 10.1097/00000433-199809000-00003  0.84
1998 Brown HG, Troncoso JC, Hoh JH. Neurofilament-L homopolymers are less mechanically stable than native neurofilaments. Journal of Microscopy. 191: 229-37. PMID 9755496 DOI: 10.1046/j.1365-2818.1998.00373.x  0.84
1998 Tseng EE, Brock MV, Lange MS, Troncoso JC, Blue ME, Lowenstein CJ, Johnston MV, Baumgartner WA. Monosialoganglioside GM1 inhibits neurotoxicity after hypothermic circulatory arrest. Surgery. 124: 298-306. PMID 9706152 DOI: 10.1016/S0039-6060(98)70134-5  0.84
1998 Baumgartner WA, Redmond JM, Zehr KJ, Brock MV, Tseng EE, Blue ME, Troncoso JC, Johnston MV. The role of the monosialoganglioside, GM1 as a neuroprotectant in an experimental model of cardiopulmonary bypass and hypothermic circulatory arrest. Annals of the New York Academy of Sciences. 845: 382-90. PMID 9668371 DOI: 10.1111/j.1749-6632.1998.tb09690.x  0.84
1998 Troncoso JC, Cataldo AM, Nixon RA, Barnett JL, Lee MK, Checler F, Fowler DR, Smialek JE, Crain B, Martin LJ, Kawas CH. Neuropathology of preclinical and clinical late-onset Alzheimer's disease. Annals of Neurology. 43: 673-6. PMID 9585365 DOI: 10.1002/ana.410430519  0.84
1997 Tseng EE, Brock MV, Lange MS, Blue ME, Troncoso JC, Kwon CC, Lowenstein CJ, Johnston MV, Baumgartner WA. Neuronal nitric oxide synthase inhibition reduces neuronal apoptosis after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 64: 1639-47. PMID 9436549 DOI: 10.1016/S0003-4975(97)01110-7  0.84
1997 Baumgartner WA, Redmond M, Brock M, Tseng E, Blue ME, Troncoso JC, Johnston MV. Pathophysiology of cerebral injury and future management. Journal of Cardiac Surgery. 12: 300-10; discussion 3. PMID 9271760  0.84
1997 Sze CI, Troncoso JC, Kawas C, Mouton P, Price DL, Martin LJ. Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 56: 933-44. PMID 9258263  1
1997 LaFerla FM, Troncoso JC, Strickland DK, Kawas CH, Jay G. Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization. The Journal of Clinical Investigation. 100: 310-20. PMID 9218507 DOI: 10.1172/JCI119536  0.52
1996 Rasmusson DX, Brandt J, Steele C, Hedreen JC, Troncoso JC, Folstein MF. Accuracy of clinical diagnosis of Alzheimer disease and clinical features of patients with non-Alzheimer disease neuropathology. Alzheimer Disease and Associated Disorders. 10: 180-8. PMID 8939276  0.84
1996 Troncoso JC, Sukhov RR, Kawas CH, Koliatsos VE. In situ labeling of dying cortical neurons in normal aging and in Alzheimer's disease: correlations with senile plaques and disease progression. Journal of Neuropathology and Experimental Neurology. 55: 1134-42. PMID 8939196  0.84
1996 Troncoso JC, Kawas CH, Chang CK, Folstein MF, Hedreen JC. Lack of association of the apoE4 allele with hippocampal sclerosis dementia. Neuroscience Letters. 204: 138-40. PMID 8929997  0.84
1996 Troncoso JC, Martin LJ, Dal Forno G, Kawas CH. Neuropathology in controls and demented subjects from the Baltimore Longitudinal Study of Aging. Neurobiology of Aging. 17: 365-71. PMID 8725897  0.52
1996 Fleming LM, Weisgraber KH, Strittmatter WJ, Troncoso JC, Johnson GV. Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins. Experimental Neurology. 138: 252-60. PMID 8620924 DOI: 10.1006/exnr.1996.0064  0.84
1995 Redmond JM, Zehr KJ, Blue ME, Lange MS, Gillinov AM, Troncoso JC, Cameron DE, Johnston MV, Baumgartner WA. AMPA glutamate receptor antagonism reduces neurologic injury after hypothermic circulatory arrest. The Annals of Thoracic Surgery. 59: 579-84. PMID 7887693 DOI: 10.1016/0003-4975(94)01047-1  0.84
1995 Furuta A, Price DL, Pardo CA, Troncoso JC, Xu ZS, Taniguchi N, Martin LJ. Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus. The American Journal of Pathology. 146: 357-67. PMID 7856748  1
1995 Raskin LS, Applegate MD, Price DL, Troncoso JC, Hedreen JC. Comparison of new and traditional methods for detection of senile plaques in Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology. 8: 125-31. PMID 7794478 DOI: 10.1177/089198879500800211  0.84
1995 West MJ, Coleman PD, Flood DG, Troncoso JC. [Differential neuronal loss in the hippocampus in normal aging and in patients with Alzheimer disease]. Ugeskrift For Laeger. 157: 3190-3. PMID 7770982  0.84
1995 Behan DP, Heinrichs SC, Troncoso JC, Liu XJ, Kawas CH, Ling N, De Souza EB. Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease. Nature. 378: 284-7. PMID 7477348 DOI: 10.1038/378284a0  0.84
1994 Redmond JM, Gillinov AM, Zehr KJ, Blue ME, Troncoso JC, Reitz BA, Cameron DE, Johnston MV, Baumgartner WA. Glutamate excitotoxicity: a mechanism of neurologic injury associated with hypothermic circulatory arrest. The Journal of Thoracic and Cardiovascular Surgery. 107: 776-86; discussion 7. PMID 8127107  0.84
1994 West MJ, Coleman PD, Flood DG, Troncoso JC. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet (London, England). 344: 769-72. PMID 7916070 DOI: 10.1016/S0140-6736(94)92338-8  0.84
1993 Greenwood JA, Troncoso JC, Costello AC, Johnson GV. Phosphorylation modulates calpain-mediated proteolysis and calmodulin binding of the 200-kDa and 160-kDa neurofilament proteins. Journal of Neurochemistry. 61: 191-9. PMID 8515266  0.84
1993 Redmond JM, Gillinov AM, Blue ME, Zehr KJ, Troncoso JC, Cameron DE, Johnston MV, Baumgartner WA. The monosialoganglioside, GM1, reduces neurologic injury associated with hypothermic circulatory arrest. Surgery. 114: 324-32; discussion 3. PMID 8393596  0.84
1993 Troncoso JC, Costello A, Watson AL, Johnson GV. In vitro polymerization of oxidized tau into filaments. Brain Research. 613: 313-6. PMID 8186983 DOI: 10.1016/0006-8993(93)90918-D  0.84
1992 Gilbert MR, Harding BL, Hoffman PN, Griffin JW, Price DL, Troncoso JC. Aluminum-induced neurofilamentous changes in cultured rat dorsal root ganglia explants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 1763-71. PMID 1578268  0.84
1992 Mercy MR, Troncoso JC, Monteiro MJ. A new series of trpE vectors that enable high expression of nonfusion proteins in bacteria. Protein Expression and Purification. 3: 57-64. PMID 1422208 DOI: 10.1016/1046-5928(92)90056-3  0.84
1991 Johnson GV, Greenwood JA, Costello AC, Troncoso JC. The regulatory role of calmodulin in the proteolysis of individual neurofilament proteins by calpain. Neurochemical Research. 16: 869-73. PMID 1787875 DOI: 10.1007/BF00965535  0.84
1991 McDonald JW, Garofalo EA, Hood T, Sackellares JC, Gilman S, McKeever PE, Troncoso JC, Johnston MV. Altered excitatory and inhibitory amino acid receptor binding in hippocampus of patients with temporal lobe epilepsy. Annals of Neurology. 29: 529-41. PMID 1650160 DOI: 10.1002/ana.410290513  0.84
1990 Pardo CA, Martin LJ, Troncoso JC, Price DL. The human pineal gland in aging and Alzheimer's disease: patterns of cytoskeletal antigen immunoreactivity. Acta Neuropathologica. 80: 535-40. PMID 2251911 DOI: 10.1007/BF00294615  0.84
1990 Price DL, Sisodia SS, Koo EH, Muma NA, Kitt CA, Walker LC, Martin LJ, Troncoso JC, Griffin JW, Hoffman PN. Neuronal disorders: studies of animal models and human diseases. Toxicologic Pathology. 18: 128-37. PMID 2195633  0.84
1990 Singer HS, Searles CD, Hahn IH, March JL, Troncoso JC. The effect of aluminum on markers for synaptic neurotransmission, cyclic AMP, and neurofilaments in a neuroblastoma x glioma hybridoma (NG108-15). Brain Research. 528: 73-9. PMID 2173966  0.52
1988 Muma NA, Troncoso JC, Hoffman PN, Koo EH, Price DL. Aluminum neurotoxicity: altered expression of cytoskeletal genes. Brain Research. 427: 115-21. PMID 3382937  0.84
1988 Naidu S, Kitt CA, Wong DF, Price DL, Troncoso JC, Moser HW. Research on Rett syndrome: strategy and preliminary results. Journal of Child Neurology. 3: S78-86. PMID 3058792  1
1988 Cork LC, Troncoso JC, Klavano GG, Johnson ES, Sternberger LA, Sternberger NH, Price DL. Neurofilamentous abnormalities in motor neurons in spontaneously occurring animal disorders. Journal of Neuropathology and Experimental Neurology. 47: 420-31. PMID 2455022  1
1987 Casanova MF, Troncoso JC, Price DL. Cerebral hemorrhagic infarcts: an autopsy study of 76 cases. BoletíN De La AsociacióN MéDica De Puerto Rico. 79: 7-11. PMID 3442583  1
1986 Troncoso JC, Sternberger NH, Sternberger LA, Hoffman PN, Price DL. Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum. Brain Research. 364: 295-300. PMID 3512034  1
1986 Casanova MF, Troncoso JC, Price DL. Hematogenous origin of brain macrophages: a case report. Neurology. 36: 844-7. PMID 3458032  1
1986 Whitehouse PJ, Muramoto O, Troncoso JC, Kanazawa I. Neurotransmitter receptors in olivopontocerebellar atrophy: an autoradiographic study. Neurology. 36: 193-7. PMID 2868427  0.36
1985 Troncoso JC, Hoffman PN, Griffin JW, Hess-Kozlow KM, Price DL. Aluminum intoxication: a disorder of neurofilament transport in motor neurons. Brain Research. 342: 172-5. PMID 4041808  1
1985 Troncoso JC, Cork LC, Price DL. Canine inherited ataxia: ultrastructural observations. Journal of Neuropathology and Experimental Neurology. 44: 165-75. PMID 3973637  1
1984 Tiemeyer MJ, Singer HS, Troncoso JC, Cork LC, Coyle JT, Price DL. Synaptic neurochemical alterations associated with neuronal degeneration in an inherited cerebellar ataxia of Gordon Setters. Journal of Neuropathology and Experimental Neurology. 43: 580-91. PMID 6502189  0.84
1983 Cork LC, Troncoso JC, Price DL, Stanley EF, Griffin JW. Canine neuroaxonal dystrophy. Journal of Neuropathology and Experimental Neurology. 42: 286-96. PMID 6842267  0.84
1982 Troncoso JC, Price DL, Griffin JW, Parhad IM. Neurofibrillary axonal pathology in aluminum intoxication. Annals of Neurology. 12: 278-83. PMID 7137964 DOI: 10.1002/ana.410120312  0.84
1982 Troncoso JC, Griffin JW, Price DL, Hess-Kozlow KM. Pathology of the peripheral neuropathy induced by p-bromophenylacetylurea. Laboratory Investigation; a Journal of Technical Methods and Pathology. 46: 215-23. PMID 7062723  1
1982 Griffin J, Cork LC, Troncoso JC, Price DL. Experimental neurotoxic disorders of motor neurons: neurofibrillary pathology. Advances in Neurology. 36: 419-33. PMID 6891174  1
1981 Steinberg HS, Troncoso JC, Cork LC, Price DL. Clinical features of inherited cerebellar degeneration in Gordon setters. Journal of the American Veterinary Medical Association. 179: 886-90. PMID 7341602  1
1981 Cork LC, Troncoso JC, Price DL. Canine inherited ataxia. Annals of Neurology. 9: 492-8. PMID 7271243 DOI: 10.1002/ana.410090512  1
1981 Troncoso JC, Johnston MV, Hess KM, Griffin JW, Price DL. Model of Wernicke's encephalopathy. Archives of Neurology. 38: 350-4. PMID 7236062 DOI: 10.1001/archneur.1981.00510060052007  0.84
Low-probability matches
2017 Mori S, Kageyama Y, Hou Z, Aggarwal M, Patel J, Brown T, Miller MI, Wu D, Troncoso JC. Elucidation of White Matter Tracts of the Human Amygdala by Detailed Comparison between High-Resolution Postmortem Magnetic Resonance Imaging and Histology. Frontiers in Neuroanatomy. 11: 16. PMID 28352217 DOI: 10.3389/fnana.2017.00016  0.24
2017 Shevelkin AV, Terrillion CE, Abazyan BN, Kajstura TJ, Jouroukhin YA, Rudow GL, Troncoso JC, Linden DJ, Pletnikov MV. Corrigendum to "Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice" [Neurobiol. Dis. 103 (2017) 144-153]. Neurobiology of Disease. PMID 28800926 DOI: 10.1016/j.nbd.2017.07.021  0.2
2017 Shevelkin AV, Terrillion CE, Abazyan BN, Kajstura TJ, Jouroukhin YA, Rudow GL, Troncoso JC, Linden DJ, Pletnikov MV. Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice. Neurobiology of Disease. PMID 28392471 DOI: 10.1016/j.nbd.2017.04.008  0.2
2010 D'Addario A, Galuppo J, Navari C, Schultz M, Cuello N, Troncoso JC, Riudavets MA. Accidental intrathecal administration of vincristine. The American Journal of Forensic Medicine and Pathology. 31: 83-4. PMID 19935391 DOI: 10.1097/PAF.0b013e3181c21c10  0.16
2005 Riudavets MA, Colegial C, Rubio A, Fowler D, Pardo C, Troncoso JC. Causes of unexpected death in patients with multiple sclerosis: a forensic study of 50 cases. The American Journal of Forensic Medicine and Pathology. 26: 244-9. PMID 16121080  0.16
2005 Riudavets MA, Aronica-Pollak P, Troncoso JC. Pseudolaminar necrosis in cyanide intoxication: a neuropathology case report. The American Journal of Forensic Medicine and Pathology. 26: 189-91. PMID 15894858  0.16
2004 Blass DM, Hatanpaa KJ, Brandt J, Rao V, Steinberg M, Troncoso JC, Rabins PV. Dementia in hippocampal sclerosis resembles frontotemporal dementia more than Alzheimer disease. Neurology. 63: 492-7. PMID 15304580  0.16
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Troncoso JC, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.12
2019 Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, et al. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathologica. PMID 31327044 DOI: 10.1007/s00401-019-02045-5  0.12
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Troncoso JC, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.12
2018 Ayhan F, Perez BA, Shorrock HK, Zu T, Banez-Coronel M, Reid T, Furuya H, Clark HB, Troncoso JC, Ross CA, Subramony SH, Ashizawa T, Wang ET, Yachnis AT, Ranum LP. SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. The Embo Journal. PMID 30206144 DOI: 10.15252/embj.201899023  0.12
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Troncoso JC, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/ng.3916  0.12
2016 Lin L, Park JW, Ramachandran S, Zhang Y, Tseng YT, Shen S, Waldvogel HJ, Curtis MA, Faull RL, Troncoso JC, Ross CA, Davidson BL, Xing Y. Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease. Human Molecular Genetics. PMID 27378699 DOI: 10.1093/hmg/ddw187  0.12
2015 Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, ... ... Troncoso JC, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/s00401-015-1509-x  0.12
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Troncoso JC, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/jamaneurol.2014.2157  0.12
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Troncoso JC, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/jamaneurol.2014.1491  0.12
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Troncoso JC, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/ng.801  0.12
2001 Margolis RL, O'Hearn E, Rosenblatt A, Willour V, Holmes SE, Franz ML, Callahan C, Hwang HS, Troncoso JC, Ross CA. A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion. Annals of Neurology. 50: 373-80. PMID 11761463  0.12
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Troncoso JC, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/j.neuron.2018.02.027  0.08
1993 Gillinov AM, Redmond JM, Zehr KJ, Troncoso JC, Arroyo S, Lesser RP, Lee AW, Stuart RS, Reitz BA, Baumgartner WA. Superior cerebral protection with profound hypothermia during circulatory arrest. The Annals of Thoracic Surgery. 55: 1432-9. PMID 8512392  0.08
1993 Arroyo S, Lesser RP, Gillinov AM, Redmond M, Zehr KJ, Troncoso JC, Jackson D, Baumgartner WA, Cameron DE. EEG and prognosis of neurologic recovery of dogs under profound hypothermic circulatory arrest. Electroencephalography and Clinical Neurophysiology. 87: 242-9. PMID 7691555  0.08
1990 Troncoso JC, March JL, Häner M, Aebi U. Effect of aluminum and other multivalent cations on neurofilaments in vitro: an electron microscopic study. Journal of Structural Biology. 103: 2-12. PMID 2397143  0.08
2018 Johnson ECB, Dammer EB, Duong DM, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Molecular Neurodegeneration. 13: 52. PMID 30286791 DOI: 10.1186/s13024-018-0282-4  0.01
2017 Valera E, Spencer B, Mott J, Trejo M, Adame A, Mante M, Rockenstein E, Troncoso JC, Beach TG, Masliah E, Desplats P. MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy. Frontiers in Molecular Neuroscience. 10: 329. PMID 29089869 DOI: 10.3389/fnmol.2017.00329  0.01
2016 Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Systems. PMID 27989508 DOI: 10.1016/j.cels.2016.11.006  0.01
2016 Rousseaux MW, de Haro M, Lasagna-Reeves CA, De Maio A, Park J, Jafar-Nejad P, Al-Ramahi I, Sharma A, See L, Lu N, Vilanova-Velez L, Klisch TJ, Westbrook TF, Troncoso JC, Botas J, et al. TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau. Elife. 5. PMID 27779468 DOI: 10.7554/eLife.19809  0.01
2016 Lasagna-Reeves CA, de Haro M, Hao S, Park J, Rousseaux MW, Al-Ramahi I, Jafar-Nejad P, Vilanova-Velez L, See L, De Maio A, Nitschke L, Wu Z, Troncoso JC, Westbrook TF, Tang J, et al. Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model. Neuron. PMID 27720485 DOI: 10.1016/j.neuron.2016.09.022  0.01
2016 Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. PMID 27718298 DOI: 10.1002/pmic.201600057  0.01
2014 Ho CY, Troncoso JC, Knox D, Stark W, Eberhart CG. Beta-amyloid, phospho-tau and alpha-synuclein deposits similar to those in the brain are not identified in the eyes of Alzheimer's and Parkinson's disease patients. Brain Pathology (Zurich, Switzerland). 24: 25-32. PMID 23714377 DOI: 10.1111/bpa.12070  0.01
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Troncoso JC, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/WNL.0b013e3182605801  0.01
2004 Gu L, Troncoso JC, Wade JB, Monteiro MJ. In vitro assembly properties of mutant and chimeric intermediate filament proteins: insight into the function of sequences in the rod and end domains of IF. Experimental Cell Research. 298: 249-61. PMID 15242779 DOI: 10.1016/j.yexcr.2004.04.020  0.01
2004 Connor JR, Wang XS, Patton SM, Menzies SL, Troncoso JC, Earley CJ, Allen RP. Decreased transferrin receptor expression by neuromelanin cells in restless legs syndrome. Neurology. 62: 1563-7. PMID 15136682  0.01
2004 Cutler RG, Kelly J, Storie K, Pedersen WA, Tammara A, Hatanpaa K, Troncoso JC, Mattson MP. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 2070-5. PMID 14970312 DOI: 10.1073/pnas.0305799101  0.01
2002 Troncoso JC, Furman P, Bisigniano L, Araujo JL, del C Bacqué M. Liver transplant: marginal donors findings from the Argentine experience. Transplantation Proceedings. 34: 227-8. PMID 11959257  0.01
2001 Eberhart CG, Morrison A, Gyure KA, Frazier J, Smialek JE, Troncoso JC. Decreasing incidence of sudden death due to undiagnosed primary central nervous system tumors. Archives of Pathology & Laboratory Medicine. 125: 1024-30. PMID 11473451 DOI: 10.1043/0003-9985(2001)125<1024:DIOSDD>2.0.CO;2  0.01
2001 Sandberg G, Stewart W, Smialek J, Troncoso JC. The prevalence of the neuropathological lesions of Alzheimer's disease is independent of race and gender. Neurobiology of Aging. 22: 169-75. PMID 11182466  0.01
1998 Brown HG, Troncoso JC, Hoh JH. Neurofilament-L homopolymers are less mechanically stable than native neurofilaments. Journal of Microscopy. 191: 229-237. PMID 9767487  0.01
1998 Morrison AL, King TM, Korell MA, Smialek JE, Troncoso JC. Acceleration-deceleration injuries to the brain in blunt force trauma. The American Journal of Forensic Medicine and Pathology. 19: 109-12. PMID 9662103  0.01
1997 McIntosh LJ, Trush MA, Troncoso JC. Increased susceptibility of Alzheimer's disease temporal cortex to oxygen free radical-mediated processes. Free Radical Biology & Medicine. 23: 183-90. PMID 9199880  0.01
1995 Troncoso JC, Costello AC, Kim JH, Johnson GV. Metal-catalyzed oxidation of bovine neurofilaments in vitro. Free Radical Biology & Medicine. 18: 891-9. PMID 7797097  0.01
1995 Knox DL, Green WR, Troncoso JC, Yardley JH, Hsu J, Zee DS. Cerebral ocular Whipple's disease: a 62-year odyssey from death to diagnosis. Neurology. 45: 617-25. PMID 7536902  0.01
1989 Becker PS, Dixon AM, Troncoso JC. Bilateral opercular polymicrogyria. Annals of Neurology. 25: 90-2. PMID 2913934 DOI: 10.1002/ana.410250115  0.01
1989 Glass JD, Becker PS, Moses H, Troncoso JC. Dural scrofula. Neurology. 39: 1123-4. PMID 2761709  0.01
1988 Fackler JC, Troncoso JC, Gioia FR. Age-specific characteristics of brain death in children. American Journal of Diseases of Children (1960). 142: 999-1003. PMID 3414634  0.01
1986 Schwender LA, Troncoso JC. Evaluation of sudden death in epilepsy. The American Journal of Forensic Medicine and Pathology. 7: 283-7. PMID 3799558  0.01
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