Roselyn J. Eisenberg - Publications

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Virology Biology, General Biology

194 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Atanasiu D, Saw WT, Cairns TM, Friedman HM, Eisenberg RJ, Cohen GH. Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion. Viruses. 15. PMID 37112875 DOI: 10.3390/v15040895  0.436
2021 Atanasiu D, Saw WT, Cairns TM, Eisenberg RJ, Cohen GH. Using Split Luciferase Assay and anti-HSV Glycoprotein Monoclonal Antibodies to Predict a Functional Binding Site Between gD and gH/gL. Journal of Virology. PMID 33504603 DOI: 10.1128/JVI.00053-21  0.492
2020 Cairns TM, Atanasiu D, Saw WT, Lou H, Whitbeck JC, Ditto NT, Bruun B, Browne H, Bennett L, Wu C, Krummenacher C, Brooks BD, Eisenberg RJ, Cohen GH. Localization of the interaction site of herpes simplex virus glycoprotein D (gD) on the membrane fusion regulator, gH/gL. Journal of Virology. PMID 32759318 DOI: 10.1128/Jvi.00983-20  0.558
2019 Beilstein F, Cohen GH, Eisenberg RJ, Nicolas V, Esclatine A, Pasdeloup D. Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopy. Plos Pathogens. 15: e1008209. PMID 31790506 DOI: 10.1371/Journal.Ppat.1008209  0.55
2019 Zuo Y, Whitbeck JC, Haila GJ, Hakim AA, Rothlauf PW, Eisenberg RJ, Cohen GH, Krummenacher C. Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1. Plos One. 14: e0223299. PMID 31581238 DOI: 10.1371/Journal.Pone.0223299  0.444
2019 Cairns TM, Ditto NT, Atanasiu D, Lou H, Brooks BD, Saw WT, Eisenberg RJ, Cohen GH. Surface plasmon resonance (SPR) reveals direct binding of HSV glycoproteins gH/gL to gD and locates a gH/gL binding site on gD. Journal of Virology. PMID 31092568 DOI: 10.1128/Jvi.00289-19  0.5
2018 Atanasiu D, Saw WT, Lazear E, Whitbeck JC, Cairns TM, Lou H, Eisenberg RJ, Cohen GH. Using antibodies and mutants to localize the presumptive gH/gL binding site on HSV gD. Journal of Virology. PMID 30282715 DOI: 10.1128/Jvi.01694-18  0.59
2018 Hook LM, Cairns TM, Awasthi S, Brooks BD, Ditto NT, Eisenberg RJ, Cohen GH, Friedman HM. Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs. Plos Pathogens. 14: e1007095. PMID 29791513 DOI: 10.1371/Journal.Ppat.1007095  0.454
2018 Vennard LM, Atanasiu D, Saw WT, Eisenberg RJ, Cohen GH, Fontana J. Recent insights into the structural characterization of herpes simplex virus fusion protein, gB Future Virology. 13: 5-7. DOI: 10.2217/Fvl-2017-0124  0.503
2017 Fontana J, Atanasiu D, Saw WT, Gallagher JR, Cox RG, Whitbeck JC, Brown LM, Eisenberg RJ, Cohen GH. The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane. Mbio. 8. PMID 28830949 DOI: 10.1128/Mbio.01268-17  0.561
2017 Cairns TM, Ditto NT, Lou H, Brooks BD, Atanasiu D, Eisenberg RJ, Cohen GH. Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging. Plos Pathogens. 13: e1006430. PMID 28614387 DOI: 10.1371/Journal.Ppat.1006430  0.43
2017 Hensel MT, Marshall JD, Dorwart MR, Heeke DS, Rao E, Tummala P, Yu L, Cohen GH, Eisenberg RJ, Sloan DD. Prophylactic Herpes Simplex Virus 2 (HSV-2) Vaccines Adjuvanted with Stable Emulsion and Toll-Like Receptor 9 Agonist Induce a Robust HSV-2-Specific Cell-Mediated Immune Response, Protect against Symptomatic Disease, and Reduce the Latent Viral Reservoir. Journal of Virology. PMID 28228587 DOI: 10.1128/Jvi.02257-16  0.415
2016 Persson J, Zhang Y, Olafsdottir TA, Thörn K, Cairns TM, Wegmann F, Sattentau QJ, Eisenberg RJ, Cohen GH, Harandi AM. Nasal Immunization Confers High Avidity Neutralizing Antibody Response and Immunity to Primary and Recurrent Genital Herpes in Guinea Pigs. Frontiers in Immunology. 7: 640. PMID 28082979 DOI: 10.3389/Fimmu.2016.00640  0.374
2016 Gilchuk I, Gilchuk P, Sapparapu G, Lampley R, Singh V, Kose N, Blum DL, Hughes LJ, Satheshkumar PS, Townsend MB, Kondas AV, Reed Z, Weiner Z, Olson VA, Hammarlund E, ... ... Eisenberg RJ, et al. Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections. Cell. 167: 684-694.e9. PMID 27768891 DOI: 10.1016/J.Cell.2016.09.049  0.437
2016 Atanasiu D, Saw WT, Eisenberg RJ, Cohen GH. Regulation of HSV glycoprotein induced cascade of events governing cell-cell fusion. Journal of Virology. PMID 27630245 DOI: 10.1128/Jvi.01501-16  0.498
2015 Cairns TM, Huang ZY, Gallagher JR, Lin Y, Lou H, Whitbeck JC, Wald A, Cohen GH, Eisenberg RJ. Patient-specific neutralizing antibody responses to herpes simplex virus are attributed to epitopes on either gD, gB, or both and can be type-specific. Journal of Virology. PMID 26109729 DOI: 10.1128/Jvi.01213-15  0.528
2015 Saw WT, Matsuda Z, Eisenberg RJ, Cohen GH, Atanasiu D. Using a split luciferase assay (SLA) to measure the kinetics of cell-cell fusion mediated by herpes simplex virus glycoproteins. Methods (San Diego, Calif.). PMID 26022509 DOI: 10.1016/J.Ymeth.2015.05.021  0.538
2014 Gallagher JR, Atanasiu D, Saw WT, Paradisgarten MJ, Whitbeck JC, Eisenberg RJ, Cohen GH. Functional fluorescent protein insertions in herpes simplex virus gB report on gB conformation before and after execution of membrane fusion. Plos Pathogens. 10: e1004373. PMID 25233449 DOI: 10.1371/Journal.Ppat.1004373  0.521
2014 Cairns TM, Huang ZY, Whitbeck JC, Ponce de Leon M, Lou H, Wald A, Krummenacher C, Eisenberg RJ, Cohen GH. Dissection of the antibody response against herpes simplex virus glycoproteins in naturally infected humans. Journal of Virology. 88: 12612-22. PMID 25142599 DOI: 10.1128/Jvi.01930-14  0.484
2014 Whitbeck JC, Huang ZY, Cairns TM, Gallagher JR, Lou H, Ponce-de-Leon M, Belshe RB, Eisenberg RJ, Cohen GH. Repertoire of epitopes recognized by serum IgG from humans vaccinated with herpes simplex virus 2 glycoprotein D. Journal of Virology. 88: 7786-95. PMID 24789783 DOI: 10.1128/Jvi.00544-14  0.439
2014 Cairns TM, Fontana J, Huang ZY, Whitbeck JC, Atanasiu D, Rao S, Shelly SS, Lou H, Ponce de Leon M, Steven AC, Eisenberg RJ, Cohen GH. Mechanism of neutralization of herpes simplex virus by antibodies directed at the fusion domain of glycoprotein B. Journal of Virology. 88: 2677-89. PMID 24352457 DOI: 10.1128/Jvi.03200-13  0.804
2014 Lazear E, Whitbeck JC, Zuo Y, Carfí A, Cohen GH, Eisenberg RJ, Krummenacher C. Induction of conformational changes at the N-terminus of herpes simplex virus glycoprotein D upon binding to HVEM and nectin-1. Virology. 448: 185-95. PMID 24314649 DOI: 10.1016/J.Virol.2013.10.019  0.473
2013 Gallagher JR, Saw WT, Atanasiu D, Lou H, Eisenberg RJ, Cohen GH. Displacement of the C terminus of herpes simplex virus gD is sufficient to expose the fusion-activating interfaces on gD. Journal of Virology. 87: 12656-66. PMID 24049165 DOI: 10.1128/Jvi.01727-13  0.54
2013 Atanasiu D, Saw WT, Gallagher JR, Hannah BP, Matsuda Z, Whitbeck JC, Cohen GH, Eisenberg RJ. Dual split protein-based fusion assay reveals that mutations to herpes simplex virus (HSV) glycoprotein gB alter the kinetics of cell-cell fusion induced by HSV entry glycoproteins. Journal of Virology. 87: 11332-45. PMID 23946457 DOI: 10.1128/Jvi.01700-13  0.763
2013 Krummenacher C, Carfí A, Eisenberg RJ, Cohen GH. Entry of herpesviruses into cells: the enigma variations. Advances in Experimental Medicine and Biology. 790: 178-95. PMID 23884592 DOI: 10.1007/978-1-4614-7651-1_10  0.547
2013 Maurer UE, Zeev-Ben-Mordehai T, Pandurangan AP, Cairns TM, Hannah BP, Whitbeck JC, Eisenberg RJ, Cohen GH, Topf M, Huiskonen JT, Grünewald K. The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction. Structure (London, England : 1993). 21: 1396-405. PMID 23850455 DOI: 10.1016/J.Str.2013.05.018  0.691
2013 Ma X, Xu RH, Roscoe F, Whitbeck JC, Eisenberg RJ, Cohen GH, Sigal LJ. The mature virion of ectromelia virus, a pathogenic poxvirus, is capable of intrahepatic spread and can serve as a target for delayed therapy. Journal of Virology. 87: 7046-53. PMID 23596297 DOI: 10.1128/Jvi.03158-12  0.492
2013 Atanasiu D, Cairns TM, Whitbeck JC, Saw WT, Rao S, Eisenberg RJ, Cohen GH. Regulation of herpes simplex virus gB-induced cell-cell fusion by mutant forms of gH/gL in the absence of gD and cellular receptors. Mbio. 4. PMID 23443004 DOI: 10.1128/Mbio.00046-13  0.588
2012 Shelly SS, Cairns TM, Whitbeck JC, Lou H, Krummenacher C, Cohen GH, Eisenberg RJ. The membrane-proximal region (MPR) of herpes simplex virus gB regulates association of the fusion loops with lipid membranes. Mbio. 3. PMID 23170000 DOI: 10.1128/Mbio.00429-12  0.822
2012 Eisenberg RJ, Atanasiu D, Cairns TM, Gallagher JR, Krummenacher C, Cohen GH. Herpes virus fusion and entry: a story with many characters. Viruses. 4: 800-32. PMID 22754650 DOI: 10.3390/V4050800  0.557
2012 Foo CH, Whitbeck JC, Ponce-de-León M, Saw WT, Cohen GH, Eisenberg RJ. The myristate moiety and amino terminus of vaccinia virus l1 constitute a bipartite functional region needed for entry. Journal of Virology. 86: 5437-51. PMID 22398293 DOI: 10.1128/Jvi.06703-11  0.78
2012 Lazear E, Whitbeck JC, Ponce-de-Leon M, Cairns TM, Willis SH, Zuo Y, Krummenacher C, Cohen GH, Eisenberg RJ. Antibody-induced conformational changes in herpes simplex virus glycoprotein gD reveal new targets for virus neutralization. Journal of Virology. 86: 1563-76. PMID 22130533 DOI: 10.1128/Jvi.06480-11  0.535
2012 Willis SH, Peng C, Leon MP, Nicola AV, Rux AH, Cohen GH, Eisenberg RJ. Expression and Purification of Secreted Forms of HSV Glycoproteins from Baculovirus-Infected Insect Cells. Methods in Molecular Medicine. 10: 131-56. PMID 21374226 DOI: 10.1385/0-89603-347-3:131  0.497
2011 Di Giovine P, Settembre EC, Bhargava AK, Luftig MA, Lou H, Cohen GH, Eisenberg RJ, Krummenacher C, Carfi A. Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1. Plos Pathogens. 7: e1002277. PMID 21980294 DOI: 10.1371/Journal.Ppat.1002277  0.528
2011 Eisenberg RJ, Cairns TM, Cohen GH. HCMV grabs a mechanism to escape neutralization. Cell Host & Microbe. 10: 177-8. PMID 21925104 DOI: 10.1016/J.Chom.2011.08.011  0.372
2011 Cohen ME, Xiao Y, Eisenberg RJ, Cohen GH, Isaacs SN. Antibody against extracellular vaccinia virus (EV) protects mice through complement and Fc receptors. Plos One. 6: e20597. PMID 21687676 DOI: 10.1371/Journal.Pone.0020597  0.41
2011 Perino J, Foo CH, Spehner D, Cohen GH, Eisenberg RJ, Crance JM, Favier AL. Role of sulfatide in vaccinia virus infection. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 103: 319-31. PMID 21554243 DOI: 10.1042/Bc20110012  0.8
2011 Cairns TM, Whitbeck JC, Lou H, Heldwein EE, Chowdary TK, Eisenberg RJ, Cohen GH. Capturing the herpes simplex virus core fusion complex (gB-gH/gL) in an acidic environment. Journal of Virology. 85: 6175-84. PMID 21507973 DOI: 10.1128/Jvi.00119-11  0.527
2011 Bernstein DI, Earwood JD, Bravo FJ, Cohen GH, Eisenberg RJ, Clark JR, Fairman J, Cardin RD. Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig. Vaccine. 29: 2071-8. PMID 21238569 DOI: 10.1016/J.Vaccine.2011.01.005  0.328
2010 Stampfer SD, Lou H, Cohen GH, Eisenberg RJ, Heldwein EE. Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. Journal of Virology. 84: 12924-33. PMID 20943984 DOI: 10.1128/Jvi.01750-10  0.466
2010 Atanasiu D, Saw WT, Cohen GH, Eisenberg RJ. Cascade of events governing cell-cell fusion induced by herpes simplex virus glycoproteins gD, gH/gL, and gB. Journal of Virology. 84: 12292-9. PMID 20861251 DOI: 10.1128/Jvi.01700-10  0.516
2010 Stiles KM, Whitbeck JC, Lou H, Cohen GH, Eisenberg RJ, Krummenacher C. Herpes simplex virus glycoprotein D interferes with binding of herpesvirus entry mediator to its ligands through downregulation and direct competition. Journal of Virology. 84: 11646-60. PMID 20826693 DOI: 10.1128/Jvi.01550-10  0.508
2010 Buchman GW, Cohen ME, Xiao Y, Richardson-Harman N, Silvera P, DeTolla LJ, Davis HL, Eisenberg RJ, Cohen GH, Isaacs SN. A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge. Vaccine. 28: 6627-36. PMID 20659519 DOI: 10.1016/J.Vaccine.2010.07.030  0.376
2010 Chowdary TK, Cairns TM, Atanasiu D, Cohen GH, Eisenberg RJ, Heldwein EE. Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL. Nature Structural & Molecular Biology. 17: 882-8. PMID 20601960 DOI: 10.1038/Nsmb.1837  0.531
2010 Atanasiu D, Whitbeck JC, de Leon MP, Lou H, Hannah BP, Cohen GH, Eisenberg RJ. Bimolecular complementation defines functional regions of Herpes simplex virus gB that are involved with gH/gL as a necessary step leading to cell fusion. Journal of Virology. 84: 3825-34. PMID 20130048 DOI: 10.1128/Jvi.02687-09  0.789
2010 Cardin R, Bravo F, Earwood J, Clark J, Eisenberg R, Cohen G, Fairman J, Bernstein D. Protection Against Genital HSV-2 in Guinea Pigs with Subunit Vaccines Containing gD2, gB2, and gH/gL Glycoprotein Antigens Complexed with CLDC Adjuvant Antiviral Research. 86: A23. DOI: 10.1016/J.Antiviral.2010.02.342  0.309
2009 Wright CC, Wisner TW, Hannah BP, Eisenberg RJ, Cohen GH, Johnson DC. Fusion between perinuclear virions and the outer nuclear membrane requires the fusogenic activity of herpes simplex virus gB. Journal of Virology. 83: 11847-56. PMID 19759132 DOI: 10.1128/Jvi.01397-09  0.766
2009 Hannah BP, Cairns TM, Bender FC, Whitbeck JC, Lou H, Eisenberg RJ, Cohen GH. Herpes simplex virus glycoprotein B associates with target membranes via its fusion loops. Journal of Virology. 83: 6825-36. PMID 19369321 DOI: 10.1128/Jvi.00301-09  0.8
2009 Whitbeck JC, Foo CH, Ponce de Leon M, Eisenberg RJ, Cohen GH. Vaccinia virus exhibits cell-type-dependent entry characteristics. Virology. 385: 383-91. PMID 19162290 DOI: 10.1016/J.Virol.2008.12.029  0.791
2009 Foo CH, Lou H, Whitbeck JC, Ponce-de-León M, Atanasiu D, Eisenberg RJ, Cohen GH. Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans. Virology. 385: 368-82. PMID 19162289 DOI: 10.1016/J.Virol.2008.12.019  0.806
2008 Fogg CN, Americo JL, Earl PL, Resch W, Aldaz-Carroll L, Eisenberg RJ, Cohen GH, Moss B. Disparity between levels of in vitro neutralization of vaccinia virus by antibody to the A27 protein and protection of mice against intranasal challenge. Journal of Virology. 82: 8022-9. PMID 18524827 DOI: 10.1128/Jvi.00568-08  0.446
2008 Xu RH, Cohen M, Tang Y, Lazear E, Whitbeck JC, Eisenberg RJ, Cohen GH, Sigal LJ. The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination. The Journal of Experimental Medicine. 205: 981-92. PMID 18391063 DOI: 10.1084/Jem.20071854  0.443
2008 Awasthi S, Lubinski JM, Eisenberg RJ, Cohen GH, Friedman HM. An HSV-1 gD mutant virus as an entry-impaired live virus vaccine. Vaccine. 26: 1195-203. PMID 18243431 DOI: 10.1016/J.Vaccine.2007.12.032  0.529
2008 Lasaro MO, Tatsis N, Hensley SE, Whitbeck JC, Lin SW, Rux JJ, Wherry EJ, Cohen GH, Eisenberg RJ, Ertl HC. Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses. Nature Medicine. 14: 205-12. PMID 18193057 DOI: 10.1038/Nm1704  0.493
2008 Stiles KM, Milne RS, Cohen GH, Eisenberg RJ, Krummenacher C. The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D. Virology. 373: 98-111. PMID 18076965 DOI: 10.1016/J.Virol.2007.11.012  0.536
2008 Lazear E, Carfi A, Whitbeck JC, Cairns TM, Krummenacher C, Cohen GH, Eisenberg RJ. Engineered disulfide bonds in herpes simplex virus type 1 gD separate receptor binding from fusion initiation and viral entry. Journal of Virology. 82: 700-9. PMID 18032483 DOI: 10.1128/Jvi.02192-07  0.517
2008 Hannah BP, Heldwein EE, Bender FC, Cohen GH, Eisenberg RJ. Mutational evidence of internal fusion loops in herpes simplex virus glycoprotein B (Journal of Virology (2007) 81, 9, (4858-4865)) Journal of Virology. 82: 7249. DOI: 10.1128/JVI.01018-08  0.711
2007 Atanasiu D, Whitbeck JC, Cairns TM, Reilly B, Cohen GH, Eisenberg RJ. Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 104: 18718-23. PMID 18003913 DOI: 10.1073/Pnas.0707452104  0.539
2007 Chen Z, Earl P, Americo J, Damon I, Smith SK, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Gorshkova I, Schuck P, Satterfield W, Moss B, Purcell R. Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model. Journal of Virology. 81: 8989-95. PMID 17581986 DOI: 10.1128/Jvi.00906-07  0.463
2007 Lawrence SJ, Lottenbach KR, Newman FK, Buller RM, Bellone CJ, Chen JJ, Cohen GH, Eisenberg RJ, Belshe RB, Stanley SL, Frey SE. Antibody responses to vaccinia membrane proteins after smallpox vaccination. The Journal of Infectious Diseases. 196: 220-9. PMID 17570109 DOI: 10.1086/518793  0.369
2007 Farnsworth A, Wisner TW, Webb M, Roller R, Cohen G, Eisenberg R, Johnson DC. Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane. Proceedings of the National Academy of Sciences of the United States of America. 104: 10187-92. PMID 17548810 DOI: 10.1073/Pnas.0703790104  0.505
2007 Aldaz-Carroll L, Xiao Y, Whitbeck JC, de Leon MP, Lou H, Kim M, Yu J, Reinherz EL, Isaacs SN, Eisenberg RJ, Cohen GH. Major neutralizing sites on vaccinia virus glycoprotein B5 are exposed differently on variola virus ortholog B6. Journal of Virology. 81: 8131-9. PMID 17522205 DOI: 10.1128/Jvi.00374-07  0.414
2007 Jing L, Chong TM, Byrd B, McClurkan CL, Huang J, Story BT, Dunkley KM, Aldaz-Carroll L, Eisenberg RJ, Cohen GH, Kwok WW, Sette A, Koelle DM. Dominance and diversity in the primary human CD4 T cell response to replication-competent vaccinia virus. Journal of Immunology (Baltimore, Md. : 1950). 178: 6374-86. PMID 17475867 DOI: 10.4049/Jimmunol.178.10.6374  0.33
2007 Cairns TM, Friedman LS, Lou H, Whitbeck JC, Shaner MS, Cohen GH, Eisenberg RJ. N-terminal mutants of herpes simplex virus type 2 gH are transported without gL but require gL for function. Journal of Virology. 81: 5102-11. PMID 17344290 DOI: 10.1128/Jvi.00097-07  0.417
2007 Hannah BP, Heldwein EE, Bender FC, Cohen GH, Eisenberg RJ. Mutational evidence of internal fusion loops in herpes simplex virus glycoprotein B. Journal of Virology. 81: 4858-65. PMID 17314168 DOI: 10.1128/Jvi.02755-06  0.781
2007 Bender FC, Samanta M, Heldwein EE, de Leon MP, Bilman E, Lou H, Whitbeck JC, Eisenberg RJ, Cohen GH. Antigenic and mutational analyses of herpes simplex virus glycoprotein B reveal four functional regions. Journal of Virology. 81: 3827-41. PMID 17267495 DOI: 10.1128/Jvi.02710-06  0.433
2007 Xiao Y, Aldaz-Carroll L, Ortiz AM, Whitbeck JC, Alexander E, Lou H, Davis HL, Braciale TJ, Eisenberg RJ, Cohen GH, Isaacs SN. A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost. Vaccine. 25: 1214-24. PMID 17098336 DOI: 10.1016/J.Vaccine.2006.10.009  0.364
2006 Horváth S, Prandovszky E, Kis Z, Krummenacher C, Eisenberg RJ, Cohen GH, Janka Z, Toldi J. Spatiotemporal changes of the herpes simplex virus entry receptor nectin-1 in murine brain during postnatal development. Journal of Neurovirology. 12: 161-70. PMID 16877297 DOI: 10.1080/13550280600760594  0.433
2006 Heldwein EE, Lou H, Bender FC, Cohen GH, Eisenberg RJ, Harrison SC. Crystal structure of glycoprotein B from herpes simplex virus 1. Science (New York, N.Y.). 313: 217-20. PMID 16840698 DOI: 10.1126/Science.1126548  0.539
2006 De Regge N, Nauwynck HJ, Geenen K, Krummenacher C, Cohen GH, Eisenberg RJ, Mettenleiter TC, Favoreel HW. Alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites. The Journal of Cell Biology. 174: 267-75. PMID 16831884 DOI: 10.1083/Jcb.200510156  0.445
2006 Whitbeck JC, Zuo Y, Milne RS, Cohen GH, Eisenberg RJ. Stable association of herpes simplex virus with target membranes is triggered by low pH in the presence of the gD receptor, HVEM. Journal of Virology. 80: 3773-80. PMID 16571794 DOI: 10.1128/Jvi.80.8.3773-3780.2006  0.478
2006 Cairns TM, Shaner MS, Zuo Y, Ponce-de-Leon M, Baribaud I, Eisenberg RJ, Cohen GH, Whitbeck JC. Epitope mapping of herpes simplex virus type 2 gH/gL defines distinct antigenic sites, including some associated with biological function. Journal of Virology. 80: 2596-608. PMID 16501070 DOI: 10.1128/Jvi.80.6.2596-2608.2006  0.519
2006 Chen Z, Earl P, Americo J, Damon I, Smith SK, Zhou YH, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Svitel J, Schuck P, Satterfield W, Moss B, et al. Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus. Proceedings of the National Academy of Sciences of the United States of America. 103: 1882-7. PMID 16436502 DOI: 10.1073/Pnas.0510598103  0.497
2005 Krummenacher C, Supekar VM, Whitbeck JC, Lazear E, Connolly SA, Eisenberg RJ, Cohen GH, Wiley DC, Carfí A. Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry. The Embo Journal. 24: 4144-53. PMID 16292345 DOI: 10.1038/Sj.Emboj.7600875  0.717
2005 Lustig S, Fogg C, Whitbeck JC, Eisenberg RJ, Cohen GH, Moss B. Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge. Journal of Virology. 79: 13454-62. PMID 16227266 DOI: 10.1128/Jvi.79.21.13454-13462.2005  0.488
2005 Bender FC, Whitbeck JC, Lou H, Cohen GH, Eisenberg RJ. Herpes simplex virus glycoprotein B binds to cell surfaces independently of heparan sulfate and blocks virus entry. Journal of Virology. 79: 11588-97. PMID 16140736 DOI: 10.1128/Jvi.79.18.11588-11597.2005  0.539
2005 Aldaz-Carroll L, Whitbeck JC, Ponce de Leon M, Lou H, Pannell LK, Lebowitz J, Fogg C, White CL, Moss B, Cohen GH, Eisenberg RJ. Physical and immunological characterization of a recombinant secreted form of the membrane protein encoded by the vaccinia virus L1R gene. Virology. 341: 59-71. PMID 16083934 DOI: 10.1016/J.Virol.2005.07.006  0.52
2005 Simpson SA, Manchak MD, Hager EJ, Krummenacher C, Whitbeck JC, Levin MJ, Freed CR, Wilcox CL, Cohen GH, Eisenberg RJ, Pizer LI. Nectin-1/HveC Mediates herpes simplex virus type 1 entry into primary human sensory neurons and fibroblasts. Journal of Neurovirology. 11: 208-18. PMID 16036799 DOI: 10.1080/13550280590924214  0.43
2005 Milne RS, Nicola AV, Whitbeck JC, Eisenberg RJ, Cohen GH. Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1. Journal of Virology. 79: 6655-63. PMID 15890903 DOI: 10.1128/Jvi.79.11.6655-6663.2005  0.556
2005 Aldaz-Carroll L, Whitbeck JC, Ponce de Leon M, Lou H, Hirao L, Isaacs SN, Moss B, Eisenberg RJ, Cohen GH. Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R. Journal of Virology. 79: 6260-71. PMID 15858010 DOI: 10.1128/Jvi.79.10.6260-6271.2005  0.545
2005 Cairns TM, Landsburg DJ, Whitbeck JC, Eisenberg RJ, Cohen GH. Contribution of cysteine residues to the structure and function of herpes simplex virus gH/gL. Virology. 332: 550-62. PMID 15680420 DOI: 10.1016/J.Virol.2004.12.006  0.412
2005 Connolly SA, Landsburg DJ, Carfi A, Whitbeck JC, Zuo Y, Wiley DC, Cohen GH, Eisenberg RJ. Potential nectin-1 binding site on herpes simplex virus glycoprotein d. Journal of Virology. 79: 1282-95. PMID 15613355 DOI: 10.1128/Jvi.79.2.1282-1295.2005  0.73
2004 Fogg C, Lustig S, Whitbeck JC, Eisenberg RJ, Cohen GH, Moss B. Protective immunity to vaccinia virus induced by vaccination with multiple recombinant outer membrane proteins of intracellular and extracellular virions. Journal of Virology. 78: 10230-7. PMID 15367588 DOI: 10.1128/Jvi.78.19.10230-10237.2004  0.487
2004 Cocchi F, Fusco D, Menotti L, Gianni T, Eisenberg RJ, Cohen GH, Campadelli-Fiume G. The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry. Proceedings of the National Academy of Sciences of the United States of America. 101: 7445-50. PMID 15123804 DOI: 10.1073/Pnas.0401883101  0.598
2004 Krummenacher C, Baribaud F, Ponce de Leon M, Baribaud I, Whitbeck JC, Xu R, Cohen GH, Eisenberg RJ. Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus. Virology. 322: 286-99. PMID 15110526 DOI: 10.1016/J.Virol.2004.02.005  0.48
2004 Linehan MM, Richman S, Krummenacher C, Eisenberg RJ, Cohen GH, Iwasaki A. In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa. Journal of Virology. 78: 2530-6. PMID 14963155 DOI: 10.1128/Jvi.78.5.2530-2536.2004  0.509
2003 Judson KA, Lubinski JM, Jiang M, Chang Y, Eisenberg RJ, Cohen GH, Friedman HM. Blocking immune evasion as a novel approach for prevention and treatment of herpes simplex virus infection. Journal of Virology. 77: 12639-45. PMID 14610186 DOI: 10.1128/Jvi.77.23.12639-12645.2003  0.508
2003 Bender FC, Whitbeck JC, Ponce de Leon M, Lou H, Eisenberg RJ, Cohen GH. Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. Journal of Virology. 77: 9542-52. PMID 12915568 DOI: 10.1128/Jvi.77.17.9542-9552.2003  0.539
2003 Krummenacher C, Baribaud I, Eisenberg RJ, Cohen GH. Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection. Journal of Virology. 77: 8985-99. PMID 12885915 DOI: 10.1128/Jvi.77.16.8985-8999.2003  0.53
2003 Milne RS, Hanna SL, Rux AH, Willis SH, Cohen GH, Eisenberg RJ. Function of herpes simplex virus type 1 gD mutants with different receptor-binding affinities in virus entry and fusion. Journal of Virology. 77: 8962-72. PMID 12885913 DOI: 10.1128/Jvi.77.16.8962-8972.2003  0.568
2003 Connolly SA, Landsburg DJ, Carfi A, Wiley DC, Cohen GH, Eisenberg RJ. Structure-based mutagenesis of herpes simplex virus glycoprotein D defines three critical regions at the gD-HveA/HVEM binding interface. Journal of Virology. 77: 8127-40. PMID 12829851 DOI: 10.1128/Jvi.77.14.8127-8140.2003  0.727
2003 Cairns TM, Milne RS, Ponce-de-Leon M, Tobin DK, Cohen GH, Eisenberg RJ. Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimeras. Journal of Virology. 77: 6731-42. PMID 12767993 DOI: 10.1128/Jvi.77.12.6731-6742.2003  0.592
2003 Richart SM, Simpson SA, Krummenacher C, Whitbeck JC, Pizer LI, Cohen GH, Eisenberg RJ, Wilcox CL. Entry of herpes simplex virus type 1 into primary sensory neurons in vitro is mediated by Nectin-1/HveC. Journal of Virology. 77: 3307-11. PMID 12584355 DOI: 10.1128/Jvi.77.5.3307-3311.2003  0.396
2002 Connolly SA, Landsburg DJ, Carfi A, Wiley DC, Eisenberg RJ, Cohen GH. Structure-based analysis of the herpes simplex virus glycoprotein D binding site present on herpesvirus entry mediator HveA (HVEM). Journal of Virology. 76: 10894-904. PMID 12368332 DOI: 10.1128/Jvi.76.21.10894-10904.2002  0.724
2002 Lubinski JM, Jiang M, Hook L, Chang Y, Sarver C, Mastellos D, Lambris JD, Cohen GH, Eisenberg RJ, Friedman HM. Herpes simplex virus type 1 evades the effects of antibody and complement in vivo. Journal of Virology. 76: 9232-41. PMID 12186907 DOI: 10.1128/Jvi.76.18.9232-9241.2002  0.504
2002 Ryzhova E, Whitbeck JC, Canziani G, Westmoreland SV, Cohen GH, Eisenberg RJ, Lackner A, González-Scarano F. Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4. Journal of Virology. 76: 7903-9. PMID 12097605 DOI: 10.1128/Jvi.76.15.7903-7909.2002  0.357
2002 Liu J, Shriver Z, Pope RM, Thorp SC, Duncan MB, Copeland RJ, Raska CS, Yoshida K, Eisenberg RJ, Cohen G, Linhardt RJ, Sasisekharan R. Characterization of a heparan sulfate octasaccharide that binds to herpes simplex virus type 1 glycoprotein D. The Journal of Biological Chemistry. 277: 33456-67. PMID 12080045 DOI: 10.1074/Jbc.M202034200  0.497
2002 Rux AH, Lou H, Lambris JD, Friedman HM, Eisenberg RJ, Cohen GH. Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b. Virology. 294: 324-32. PMID 12009874 DOI: 10.1006/Viro.2001.1326  0.496
2002 Carfí A, Gong H, Lou H, Willis SH, Cohen GH, Eisenberg RJ, Wiley DC. Crystallization and preliminary diffraction studies of the ectodomain of the envelope glycoprotein D from herpes simplex virus 1 alone and in complex with the ectodomain of the human receptor HveA. Acta Crystallographica. Section D, Biological Crystallography. 58: 836-8. PMID 11976496 DOI: 10.1107/S0907444902001270  0.464
2002 Krummenacher C, Baribaud I, Sanzo JF, Cohen GH, Eisenberg RJ. Effects of herpes simplex virus on structure and function of nectin-1/HveC. Journal of Virology. 76: 2424-33. PMID 11836420 DOI: 10.1128/Jvi.76.5.2424-2433.2002  0.551
2001 Huber MT, Wisner TW, Hegde NR, Goldsmith KA, Rauch DA, Roller RJ, Krummenacher C, Eisenberg RJ, Cohen GH, Johnson DC. Herpes simplex virus with highly reduced gD levels can efficiently enter and spread between human keratinocytes. Journal of Virology. 75: 10309-18. PMID 11581399 DOI: 10.1128/Jvi.75.21.10309-10318.2001  0.501
2001 Carfí A, Willis SH, Whitbeck JC, Krummenacher C, Cohen GH, Eisenberg RJ, Wiley DC. Herpes simplex virus glycoprotein D bound to the human receptor HveA. Molecular Cell. 8: 169-79. PMID 11511370 DOI: 10.1016/S1097-2765(01)00298-2  0.53
2001 Geraghty RJ, Fridberg A, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG. Use of chimeric nectin-1(HveC)-related receptors to demonstrate that ability to bind alphaherpesvirus gD is not necessarily sufficient for viral entry. Virology. 285: 366-75. PMID 11437670 DOI: 10.1006/Viro.2001.0989  0.565
2001 Milne RS, Connolly SA, Krummenacher C, Eisenberg RJ, Cohen GH. Porcine HveC, a member of the highly conserved HveC/nectin 1 family, is a functional alphaherpesvirus receptor. Virology. 281: 315-28. PMID 11277703 DOI: 10.1006/Viro.2000.0798  0.728
2001 Connolly SA, Whitbeck JJ, Rux AH, Krummenacher C, van Drunen Littel-van den Hurk S, Cohen GH, Eisenberg RJ. Glycoprotein D homologs in herpes simplex virus type 1, pseudorabies virus, and bovine herpes virus type 1 bind directly to human HveC(nectin-1) with different affinities. Virology. 280: 7-18. PMID 11162814 DOI: 10.1006/Viro.2000.0747  0.751
2001 Whitbeck JC, Connolly SA, Willis SH, Hou W, Krummenacher C, Ponce de Leon M, Lou H, Baribaud I, Eisenberg RJ, Cohen GH. Localization of the gD-binding region of the human herpes simplex virus receptor, HveA. Journal of Virology. 75: 171-80. PMID 11119586 DOI: 10.1128/Jvi.75.1.171-180.2001  0.687
2000 Sarrias MR, Whitbeck JC, Rooney I, Ware CF, Eisenberg RJ, Cohen GH, Lambris JD. The three HveA receptor ligands, gD, LT-alpha and LIGHT bind to distinct sites on HveA. Molecular Immunology. 37: 665-73. PMID 11164894 DOI: 10.1016/S0161-5890(00)00089-4  0.423
2000 Krummenacher C, Baribaud I, Ponce De Leon M, Whitbeck JC, Lou H, Cohen GH, Eisenberg RJ. Localization of a binding site for herpes simplex virus glycoprotein D on herpesvirus entry mediator C by using antireceptor monoclonal antibodies Journal of Virology. 74: 10863-10872. PMID 11069980 DOI: 10.1128/Jvi.74.23.10863-10872.2000  0.541
2000 Spear PG, Eisenberg RJ, Cohen GH. Three classes of cell surface receptors for alphaherpesvirus entry. Virology. 275: 1-8. PMID 11017782 DOI: 10.1006/Viro.2000.0529  0.596
2000 McDermott BM, Rux AH, Eisenberg RJ, Cohen GH, Racaniello VR. Two distinct binding affinities of poliovirus for its cellular receptor. The Journal of Biological Chemistry. 275: 23089-96. PMID 10770940 DOI: 10.1074/Jbc.M002146200  0.306
1999 Whitbeck JC, Muggeridge MI, Rux AH, Hou W, Krummenacher C, Lou H, Van Geelen A, Eisenberg RJ, Cohen GH. The major neutralizing antigenic site on herpes simplex virus glycoprotein D overlaps a receptor-binding domain Journal of Virology. 73: 9879-9890. PMID 10559300 DOI: 10.1128/Jvi.73.12.9879-9890.1999  0.555
1999 Canziani G, Zhang W, Cines D, Rux A, Willis S, Cohen G, Eisenberg R, Chaiken I. Exploring biomolecular recognition using optical biosensors Methods: a Companion to Methods in Enzymology. 19: 253-269. PMID 10527730 DOI: 10.1006/Meth.1999.0855  0.307
1999 Shukla D, Liu J, Blaiklock P, Shworak NW, Bai X, Esko JD, Cohen GH, Eisenberg RJ, Rosenberg RD, Spear PG. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Cell. 99: 13-22. PMID 10520990 DOI: 10.1016/S0092-8674(00)80058-6  0.554
1999 Krummenacher C, Rux AH, Whitbeck JC, Ponce-de-Leon M, Lou H, Baribaud I, Hou W, Zou C, Geraghty RJ, Spear PG, Eisenberg RJ, Cohen GH. The first immunoglobulin-like domain of HveC is sufficient to bind herpes simplex virus gD with full affinity, while the third domain is involved in oligomerization of HveC. Journal of Virology. 73: 8127-37. PMID 10482562 DOI: 10.1128/Jvi.73.10.8127-8137.1999  0.445
1999 Pilling A, Rosenberg MF, Willis SH, Jäger J, Cohen GH, Eisenberg RJ, Meredith DM, Holzenburg A. Three-dimensional structure of herpes simplex virus type 1 glycoprotein D at 2.4-Nanometer resolution Journal of Virology. 73: 7830-7834. PMID 10438875 DOI: 10.1128/Jvi.73.9.7830-7834.1999  0.583
1999 Sarrias MR, Whitbeck JC, Rooney I, Spruce L, Kay BK, Montgomery RI, Spear PG, Ware CF, Eisenberg RJ, Cohen GH, Lambris JD. Inhibition of herpes simplex virus gD and lymphotoxin-alpha binding to HveA by peptide antagonists. Journal of Virology. 73: 5681-7. PMID 10364318 DOI: 10.1128/Jvi.73.7.5681-5687.1999  0.474
1998 Lubinski JM, Wang L, Soulika AM, Burger R, Wetsel RA, Colten H, Cohen GH, Eisenberg RJ, Lambris JD, Friedman HM. Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivo Journal of Virology. 72: 8257-8263. PMID 9733869 DOI: 10.1128/Jvi.72.10.8257-8263.1998  0.515
1998 Rux AH, Willis SH, Nicola AV, Hou W, Peng C, Lou H, Cohen GH, Eisenberg RJ. Functional region IV of glycoprotein D from herpes simplex virus modulates glycoprotein binding to the herpesvirus entry mediator Journal of Virology. 72: 7091-7098. PMID 9696802 DOI: 10.1128/Jvi.72.9.7091-7098.1998  0.524
1998 Krummenacher C, Nicola AV, Whitbeck JC, Lou H, Hou W, Lambris JD, Geraghty RJ, Spear PG, Cohen GH, Eisenberg RJ. Herpes simplex virus glycoprotein D can bind to poliovirus receptor-related protein 1 or herpesvirus entry mediator, two structurally unrelated mediators of virus entry. Journal of Virology. 72: 7064-74. PMID 9696799 DOI: 10.1128/Jvi.72.9.7064-7074.1998  0.548
1998 Warner MS, Geraghty RJ, Martinez WM, Montgomery RI, Whitbeck JC, Xu R, Eisenberg RJ, Cohen GH, Spear PG. A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus. Virology. 246: 179-89. PMID 9657005 DOI: 10.1006/Viro.1998.9218  0.535
1998 Peng T, Ponce de Leon M, Novotny MJ, Jiang H, Lambris JD, Dubin G, Spear PG, Cohen GH, Eisenberg RJ. Structural and antigenic analysis of a truncated form of the herpes simplex virus glycoprotein gH-gL complex. Journal of Virology. 72: 6092-103. PMID 9621073 DOI: 10.1128/Jvi.72.7.6092-6103.1998  0.477
1998 Willis SH, Rux AH, Peng C, Whitbeck JC, Nicola AV, Lou H, Hou W, Salvador L, Eisenberg RJ, Cohen GH. Examination of the kinetics of herpes simplex virus glycoprotein D binding to the herpesvirus entry mediator, using surface plasmon resonance Journal of Virology. 72: 5937-5947. PMID 9621056 DOI: 10.1128/Jvi.72.7.5937-5947.1998  0.498
1998 Terry-Allison T, Montgomery RI, Whitbeck JC, Xu R, Cohen GH, Eisenberg RJ, Spear PG. HveA (herpesvirus entry mediator A), a coreceptor for herpes simplex virus entry, also participates in virus-induced cell fusion. Journal of Virology. 72: 5802-10. PMID 9621040 DOI: 10.1128/Jvi.72.7.5802-5810.1998  0.547
1998 Geraghty RJ, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG. Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor. Science (New York, N.Y.). 280: 1618-20. PMID 9616127 DOI: 10.1126/Science.280.5369.1618  0.537
1998 Nicola AV, Ponce De Leon M, Xu R, Hou W, Whitbeck JC, Krummenacher C, Montgomery RI, Spear PG, Eisenberg RJ, Cohen GH. Monoclonal antibodies to distinct sites on herpes simplex virus (HSV) glycoprotein D block HSV binding to HVEM Journal of Virology. 72: 3595-3601. PMID 9557640 DOI: 10.1128/Jvi.72.5.3595-3601.1998  0.566
1998 Mauri DN, Ebner R, Montgomery RI, Kochel KD, Cheung TC, Yu GL, Ruben S, Murphy M, Eisenberg RJ, Cohen GH, Spear PG, Ware CF. LIGHT, a new member of the TNF superfamily, and lymphotoxin α are ligands for herpesvirus entry mediator Immunity. 8: 21-30. PMID 9462508 DOI: 10.1016/S1074-7613(00)80455-0  0.442
1998 Peng T, Ponce-De-Leon M, Jiang H, Dubin G, Lubinski JM, Eisenberg RJ, Cohen GH. The gH-gL complex of herpes simplex virus (HSV) stimulates neutralizing antibody and protects mice against HSV type 1 challenge Journal of Virology. 72: 65-72. PMID 9420201 DOI: 10.1128/Jvi.72.1.65-72.1998  0.496
1997 Whitbeck JC, Peng C, Lou H, Xu R, Willis SH, Ponce De Leon M, Peng T, Nicola AV, Montgomery RI, Warner MS, Soulika AM, Spruce LA, Moore WT, Lambris JD, Spear PG, ... ... Eisenberg RJ, et al. Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry Journal of Virology. 71: 6083-6093. PMID 9223502 DOI: 10.1128/Jvi.71.8.6083-6093.1997  0.49
1997 Nicola AV, Peng C, Lou H, Cohen GH, Eisenberg RJ. Antigenic structure of soluble herpes simplex virus (HSV) glycoprotein D correlates with inhibition of HSV infection Journal of Virology. 71: 2940-2946. PMID 9060653 DOI: 10.1128/Jvi.71.4.2940-2946.1997  0.489
1997 Kostavasili I, Sahu A, Friedman HM, Eisenberg RJ, Cohen GH, Lambris JD. Mechanism of Complement Inactivation by Glycoprotein C of Herpes Simplex Virus Journal of Immunology. 158: 1763-1771. PMID 9029114  0.318
1996 Handler CG, Cohen GH, Eisenberg RJ. Cross-linking of glycoprotein oligomers during herpes simplex virus type 1 entry Journal of Virology. 70: 6076-6082. PMID 8709231  0.393
1996 Handler CG, Eisenberg RJ, Cohen GH. Oligomeric structure of glycoproteins in herpes simplex virus type 1 Journal of Virology. 70: 6067-6075. PMID 8709230  0.386
1996 Nicola AV, Willis SH, Naidoo NN, Eisenberg RJ, Cohen GH. Structure-function analysis of soluble forms of herpes simplex virus glycoprotein D Journal of Virology. 70: 3815-3822. PMID 8648717 DOI: 10.1128/Jvi.70.6.3815-3822.1996  0.521
1996 Rux JJ, Willis SH, Burnett RM, Cohen GH, Eisenberg RJ. Crystallization and preliminary X-ray analysis of herpes simplex virus neutralizing antibody Fab fragment DL11 Acta Crystallographica Section D: Biological Crystallography. 52: 583-585. DOI: 10.1107/S0907444995016453  0.425
1996 Friedman HM, Wang L, Fishman NO, Lambris J, Eisenberg RJ, Cohen GH, Pangburn MK, Lubinski J. Immune evasion properties of herpes simplex virus type 1 glycoprotein gc Journal of Investigative Medicine. 44: 218a.  0.343
1995 Tal-Singer R, Peng C, Ponce de Leon M, Abrams WR, Banfield BW, Tufaro F, Cohen GH, Eisenberg RJ. Interaction of herpes simplex virus glycoprotein gC with mammalian cell surface molecules Journal of Virology. 69: 4471-4483. PMID 7769707  0.418
1994 Sisk WP, Bradley JD, Leipold RJ, Stoltzfus AM, Ponce De Leon M, Hilf M, Peng C, Cohen GH, Eisenberg RJ. High-level expression and purification of secreted forms of herpes simplex virus type 1 glycoprotein gD synthesized by baculovirus-infected insect cells Journal of Virology. 68: 766-775. PMID 8289380  0.41
1994 Hung SL, Peng C, Kostavasili I, Friedman HM, Lambris JD, Eisenberg RJ, Cohen GH. The interaction of glycoprotein C of herpes simplex virus types 1 and 2 with the alternative complement pathway Virology. 203: 299-312. PMID 8053154 DOI: 10.1006/Viro.1994.1488  0.492
1994 Tal-Singer R, Eisenberg RJ, Valyi-Nagy T, Fraser NW, Cohen GH. N-linked oligosaccharides on herpes simplex virus glycoprotein gD are not essential for establishment of viral latency or reactivation in the mouse eye model. Virology. 202: 1050-3. PMID 8030209 DOI: 10.1006/Viro.1994.1437  0.5
1994 Koelle DM, Corey L, Burke RL, Eisenberg RJ, Cohen GH, Pichyangkura R, Triezenberg SJ. Antigenic specificities of human CD4+ T-cell clones recovered from recurrent genital herpes simplex virus type 2 lesions Journal of Virology. 68: 2803-2810. PMID 7512152 DOI: 10.1128/Jvi.68.5.2803-2810.1994  0.444
1994 Chiang HY, Cohen GH, Eisenberg RJ. Identification of functional regions of herpes simplex virus glycoprotein gD by using linker-insertion mutagenesis Journal of Virology. 68: 2529-2543. PMID 7511173  0.422
1992 Hung SL, Srinivasan S, Friedman HM, Eisenberg RJ, Cohen GH. Structural basis of C3b binding by glycoprotein C of herpes simplex virus Journal of Virology. 66: 4013-4027. PMID 1602532  0.377
1992 Cohen GH, Muggeridge MI, Long D, Sodora DA, Eisenberg RJ. Structural and functional studies of herpes simplex virus glycoprotein D Advances in Experimental Medicine and Biology. 327: 217-228. PMID 1338265  0.344
1992 Long D, Wilcox WC, Abrams WR, Cohen GH, Eisenberg RJ. Disulfide bond structure of glycoprotein D of herpes simplex virus types 1 and 2 Journal of Virology. 66: 6668-6685. PMID 1328685  0.311
1992 Dubin G, Fishman NO, Eisenberg RJ, Cohen GH, Friedman HM. The role of herpes simplex virus glycoproteins in immune evasion Current Topics in Microbiology and Immunology. 179: 111-120. PMID 1323450 DOI: 10.1007/978-3-642-77247-4_7  0.447
1992 Muggeridge MI, Cohen GH, Eisenberg RJ. Herpes simplex virus infection can occur without involvement of the fibroblast growth factor receptor Journal of Virology. 66: 824-830. PMID 1309916  0.398
1991 Lausch RN, Staats H, Oakes JE, Cohen GH, Eisenberg RJ. Prevention of herpes keratitis by monoclonal antibodies specific for discontinuous and continuous epitopes on glycoprotein D Investigative Ophthalmology and Visual Science. 32: 2735-2740. PMID 1716618  0.349
1991 Tal-Singer R, Seidel-Dugan C, Fries L, Huemer HP, Eisenberg RJ, Cohen GH, Friedman HM. Herpes simplex virus glycoprotein C is a receptor for complement component iC3b Journal of Infectious Diseases. 164: 750-753. PMID 1654359 DOI: 10.1093/Infdis/164.4.750  0.545
1991 Roberts SR, Ponce de Leon M, Cohen GH, Eisenberg RJ. Analysis of the intracellular maturation of the herpes simplex virus type 1 glycoprotein gH in infected and transfected cells Virology. 184: 609-624. PMID 1653491 DOI: 10.1016/0042-6822(91)90431-A  0.52
1991 Sodora DL, Eisenberg RJ, Cohen GH. Characterization of a recombinant herpes simplex virus which expresses a glycoprotein D lacking asparagine-linked oligosaccharides Journal of Virology. 65: 4432-4441. PMID 1649339 DOI: 10.1128/Jvi.65.8.4432-4441.1991  0.54
1991 Sodora DL, Cohen GH, Muggeridge MI, Eisenberg RJ. Absence of asparagine-linked oligosaccharides from glycoprotein D of herpes simplex virus type 1 results in a structurally altered but biologically active protein Journal of Virology. 65: 4424-4431. PMID 1649338 DOI: 10.1128/Jvi.65.8.4424-4431.1991  0.471
1991 Fasel NJ, Bernard M, Déglon N, Rousseaux M, Eisenberg RJ, Bron C, Cohen GH. Isolation from mouse fibroblasts of a cDNA encoding a new form of the fibroblast growth factor receptor (flg) Biochemical and Biophysical Research Communications. 178: 8-15. PMID 1648916 DOI: 10.1016/0006-291X(91)91772-5  0.363
1990 Long D, Cohen GH, Muggeridge MI, Eisenberg RJ. Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function Journal of Virology. 64: 5542-5552. PMID 2170686  0.389
1990 Harris SL, Frank I, Yee A, Cohen GH, Eisenberg RJ, Friedman HM. Glycoprotein C of herpes simplex virus type 1 prevents complement-mediated cell lysis and virus neutralization Journal of Infectious Diseases. 162: 331-337. PMID 2165106 DOI: 10.1093/infdis/162.2.331  0.476
1990 Seidel-Dugan C, Ponce de Leon M, Friedman HM, Eisenberg RJ, Cohen GH. Identification of C3b-binding regions on herpes simplex virus type 2 glycoprotein C Journal of Virology. 64: 1897-1906. PMID 2157859  0.388
1990 Muggeridge MI, Wu TT, Johnson DC, Glorioso JC, Eisenberg RJ, Cohen GH. Antigenic and functional analysis of a neutralization site of HSV-1 glycoprotein D. Virology. 174: 375-87. PMID 2154881 DOI: 10.1016/0042-6822(90)90091-5  0.496
1990 Muggeridge MI, Wilcox WC, Cohen GH, Eisenberg RJ. Identification of a site on herpes simplex virus type 1 glycoprotein D that is essential for infectivity Journal of Virology. 64: 3617-3626. PMID 1695252  0.511
1989 Sodora DL, Cohen GH, Eisenberg RJ. Influence of asparagine-linked oligosaccharides on antigenicity, processing, and cell surface expression of herpes simplex virus type 1 glycoprotein D Journal of Virology. 63: 5184-5193. PMID 2555549 DOI: 10.1128/Jvi.63.12.5184-5193.1989  0.456
1989 Friedman HM, Yee A, Diggelmann H, Hastings JC, Tal-Singer R, Seidel-Dugan CA, Eisenberg RJ, Cohen GH. Use of a glucocorticoid-inducible promoter for expression of herpes simplex virus type 1 glycoprotein gC1, a cytotoxic protein in mammalian cells Molecular and Cellular Biology. 9: 2303-2314. PMID 2548078 DOI: 10.1128/Mcb.9.6.2303  0.414
1989 Isola VJ, Eisenberg RJ, Siebert GR, Heilman CJ, Wilcox WC, Cohen GH. Fine mapping of antigenic site II of herpes simplex virus glycoprotein D Journal of Virology. 63: 2325-2334. PMID 2467994  0.355
1988 Seidel-Dugan C, Ponce de Leon M, Friedman HM, Fries LF, Frank MM, Cohen GH, Eisenberg RJ. C3b receptor activity on transfected cells expressing glycoprotein C of herpes simplex virus types 1 and 2. Journal of Virology. 62: 4027-36. PMID 2845122  0.464
1988 Muggeridge MI, Isola VJ, Byrn RA, Tucker TJ, Minson AC, Glorioso JC, Cohen GH, Eisenberg RJ. Antigenic analysis of a major neutralization site of herpes simplex virus glycoprotein D, using deletion mutants and monoclonal antibody-resistant mutants. Journal of Virology. 62: 3274-80. PMID 2841479  0.348
1988 Wilcox WC, Long D, Sodora DL, Eisenberg RJ, Cohen GH. The contribution of cysteine residues to antigenicity and extent of processing of herpes simplex virus type 1 glycoprotein D Journal of Virology. 62: 1941-1947. PMID 2835498 DOI: 10.1128/Jvi.62.6.1941-1947.1988  0.509
1988 Wyckoff JH, Osmand AP, Eisenberg RJ, Cohen GH, Rouse BT. Functional T cell recognition of synthetic peptides corresponding to continuous antibody epitopes of herpes simplex virus type 1 glycoprotein D Immunobiology. 177: 134-148. PMID 2456985 DOI: 10.1016/S0171-2985(88)80034-2  0.373
1988 Cohen GH, Wilcox WC, Sodora DL, Long D, Levin JZ, Eisenberg RJ. Expression of herpes simplex virus type 1 glycoprotein D deletion mutants in mammalian cells Journal of Virology. 62: 1932-1940. PMID 2452897 DOI: 10.1128/Jvi.62.6.1932-1940.1988  0.499
1987 Torseth JW, Cohen GH, Eisenberg RJ, Berman PW, Lasky LA, Cerini CP, Heilman CJ, Kerwar S, Merigan TC. Native and recombinant herpes simplex virus type 1 envelope proteins induce human immune T-lymphocyte responses. Journal of Virology. 61: 1532-9. PMID 3033279 DOI: 10.1128/Jvi.61.5.1532-1539.1987  0.427
1987 Eisenberg RJ, de Leon MP, Friedman HM, Fries LF, Frank MM, Hastings JC, Cohen GH. Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2 Microbial Pathogenesis. 3: 423-435. PMID 2849025 DOI: 10.1016/0882-4010(87)90012-X  0.446
1986 Friedman HM, Glorioso JC, Cohen GH, Hastings JC, Harris SL, Eisenberg RJ. Binding of complement component C3b to glycoprotein gC of herpes simplex virus type 1: mapping of gC-binding sites and demonstration of conserved C3b binding in low-passage clinical isolates. Journal of Virology. 60: 470-5. PMID 3021981  0.356
1986 Fries LF, Friedman HM, Cohen GH, Eisenberg RJ, Hammer CH, Frank MM. Glycoprotein C of herpes simplex virus 1 is an inhibitor of the complement cascade Journal of Immunology. 137: 1636-1641. PMID 3018078  0.367
1986 Cohen GH, Isola VJ, Kuhns J, Berman PW, Eisenberg RJ. Localization of discontinuous epitopes of herpes simplex virus glycoprotein D: use of a nondenaturing ("native" gel) system of polyacrylamide gel electrophoresis coupled with Western blotting. Journal of Virology. 60: 157-66. PMID 2427745 DOI: 10.1128/Jvi.60.1.157-166.1986  0.424
1985 Eisenberg RJ, Cerini CP, Heilman CJ, Joseph AD, Dietzschold B, Golub E, Long D, Ponce de Leon M, Cohen GH. Synthetic glycoprotein D-related peptides protect mice against herpes simplex virus challenge. Journal of Virology. 56: 1014-7. PMID 2999419 DOI: 10.1128/Jvi.56.3.1014-1017.1985  0.378
1985 Eisenberg RJ, Long D, Ponce de Leon M, Matthews JT, Spear PG, Gibson MG, Lasky LA, Berman P, Golub E, Cohen GH. Localization of epitopes of herpes simplex virus type 1 glycoprotein D Journal of Virology. 53: 634-644. PMID 2578577 DOI: 10.1128/Jvi.53.2.634-644.1985  0.425
1984 Friedman HM, Cohen GH, Eisenberg RJ, Seidel CA, Cines DB. Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells Nature. 309: 633-635. PMID 6328323 DOI: 10.1038/309633A0  0.489
1984 Long D, Madara TJ, Ponce de Leon M, Cohen GH, Montgomery PC, Eisenberg RJ. Glycoprotein D protects mice against lethal challenge with herpes simplex virus types 1 and 2 Infection and Immunity. 43: 761-764. PMID 6319291 DOI: 10.1128/Iai.43.2.761-764.1984  0.447
1984 Costa RH, Cohen G, Eisenberg R, Long D, Wagner E. Direct demonstration that the abundant 6-kilobase herpes simplex virus type 1 mRNA mapping between 0.23 and 0.27 map units encodes the major capsid protein VP5. Journal of Virology. 49: 287-292. PMID 6317894 DOI: 10.1128/Jvi.49.1.287-292.1984  0.377
1984 Eisenberg RJ, Long D, Hogue Angeletti R, Cohen GH. Amino-terminal sequence of glycoprotein D of herpes simplex virus types 1 and 2 Journal of Virology. 49: 265-268. PMID 6317892 DOI: 10.1128/Jvi.49.1.265-268.1984  0.437
1984 Dietzschold B, Eisenberg RJ, Ponce de Leon M, Golub E, Hudecz F, Varrichio A, Cohen GH. Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D Journal of Virology. 52: 431-435. PMID 6208376 DOI: 10.1128/Jvi.52.2.431-435.1984  0.495
1984 Cohen GH, Dietzschold B, Ponce de Leon M, Long D, Golub E, Varrichio A, Pereira L, Eisenberg RJ. Localization and synthesis of an antigenic determinant of herpes simplex virus glycoprotein D that stimulates the production of neutralizing antibody Journal of Virology. 49: 102-108. PMID 6197535 DOI: 10.1128/Jvi.49.1.102-108.1984  0.447
1983 Costa RH, Draper KG, Banks L, Powell KL, Cohen G, Eisenberg R, Wagner EK. High-resolution characterization of herpes simplex virus type 1 transcripts encoding alkaline exonuclease and a 50,000-dalton protein tentatively identified as a capsid protein. Journal of Virology. 48: 591-603. PMID 6313961 DOI: 10.1128/Jvi.48.3.591-603.1983  0.38
1983 Matthews JT, Cohen GH, Eisenberg RJ. Synthesis and processing of glycoprotein D of herpes simplex virus types 1 and 2 in an in vitro system Journal of Virology. 48: 521-533. PMID 6312106 DOI: 10.1128/Jvi.48.2.521-533.1983  0.44
1983 Frink RJ, Eisenberg R, Cohen G, Wagner EK. Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C. Journal of Virology. 45: 634-47. PMID 6300426 DOI: 10.1128/Jvi.45.2.634-647.1983  0.311
1983 Cohen GH, Long D, Matthews JT, May M, Eisenberg R. Glycopeptides of the Type-Common Glycoprotein gD of Herpes Simplex Virus Types 1 and 2 Journal of Virology. 46: 679-689. DOI: 10.1128/Jvi.46.3.679-689.1983  0.332
1982 Eisenberg RJ, Ponce De Leon M, Pereira L, Long D, Cohen GH. Purification of glycoprotein gD of herpes simplex virus types 1 and 2 by use of monoclonal antibody Journal of Virology. 41: 1099-1104. PMID 6284965 DOI: 10.1128/Jvi.41.3.1099-1104.1982  0.466
1982 Eisenberg R, Long D, Pereira L, Hampar B, Zweig M, Cohen GH. Effect of monoclonal antibodies on limited proteolysis of native glycoprotein gD of herpes simplex virus type 1 Journal of Virology. 41: 478-488. PMID 6176725 DOI: 10.1128/Jvi.41.2.478-488.1982  0.384
1982 Eisenberg RJ, Long D, Pereira L, Hampar B, Zweig M, Cohen GH. Effect of monoclonal antibodies on limited proteolysis of native glycoprotein gD of herpes simplex virus type 1. Journal of Virology. 41: 478-488. DOI: 10.1128/jvi.41.2.478-488.1982  0.394
1981 Vernon SK, Ponce de Leon M, Cohen GH, Eisenberg RJ, Rubin BA. Morphological components of herpesvirus. III. Localization of herpes simplex virus type 1 nucleocapsid polypeptides by immune electron microscopy Journal of General Virology. 54: 39-46. PMID 6270247 DOI: 10.1099/0022-1317-54-1-39  0.401
1980 Eisenberg RJ, Ponce de Leon M, Cohen GH. Comparative structural analysis of glycoprotein gD of herpes simplex virus types 1 and 2 Journal of Virology. 35: 428-435. PMID 6255183  0.339
1980 Cohen GH, Long D, Eisenberg RJ. Synthesis and processing of glycoproteins gD and gC of herpes simplex virus type 1 Journal of Virology. 36: 429-439. PMID 6253668 DOI: 10.1128/Jvi.36.2.429-439.1980  0.363
1980 Pizer LI, Cohen GH, Eisenberg RJ. Effect of tunicamycin on herpes simplex virus glycoproteins and infectious virus production Journal of Virology. 34: 142-153. PMID 6246250 DOI: 10.1128/Jvi.34.1.142-153.1980  0.52
1980 Cohen GH, Ponce De Leon M, Diggelmann H, Lawrence WC, Vernon SK, Eisenberg RJ. Structural analysis of capsid polypeptides of herpes simplex virus types 1 and 2 Journal of Virology. 34: 521-531. PMID 6154808  0.302
1979 Eisenberg RJ, Hydrean-Stern C, Cohen GH. Structural analysis of precursor and product forms of type-common envelope glycoprotein D (CP-1 antigen) of herpes simplex virus type 1 Journal of Virology. 31: 608-620. PMID 229243 DOI: 10.1128/Jvi.31.3.608-620.1979  0.361
1979 Pizer LI, Cohen GH, Eisenberg RJ. Tunicamycin alters herpes virus glycoprotein maturation Journal of Supramolecular and Cellular Biochemistry. 237.  0.421
1978 Cohen GH, Katze M, Hydrean-Stern C, Eisenberg RJ. Type-common CP-1 antigen of herpes simplex virus is associated with a 59,000-molecular-weight envelope glycoprotein Journal of Virology. 27: 172-181. PMID 80458 DOI: 10.1128/Jvi.27.1.172-181.1978  0.479
1977 Ponce de Leon M, Eisenberg RJ, Cohen GH. Ribonucleotide reductase from herpes simplex virus (types 1 and 2) infected and uninfected KB cells: properties of the partially purified enzymes Journal of General Virology. 36: 163-173. PMID 18550 DOI: 10.1099/0022-1317-36-1-163  0.422
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