| Year |
Citation |
Score |
| 2024 |
Guo Q, Ping L, Dammer EB, Duong DM, Yin L, Xu K, Shantaraman A, Fox EJ, Golde TE, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease. Molecular Neurodegeneration. 19: 67. PMID 39380021 DOI: 10.1186/s13024-024-00757-1 |
0.35 |
|
| 2024 |
Paterno G, Moore BD, Bell BM, Gorion KM, Ran Y, Prokop S, Golde TE, Giasson BI. Novel Monoclonal Antibody Specific toward Amyloid-β Binds to a Unique Epitope within the N-Terminal Region. Antibodies (Basel, Switzerland). 13. PMID 39189239 DOI: 10.3390/antib13030068 |
0.697 |
|
| 2024 |
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips J, Iturbe A, Erquizi A, Moore BD, Ryu D, Natu A, ... ... Golde TE, et al. Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease. Cell Reports. Medicine. 101669. PMID 39127040 DOI: 10.1016/j.xcrm.2024.101669 |
0.77 |
|
| 2024 |
Seifar F, Fox EJ, Shantaraman A, Liu Y, Dammer EB, Modeste E, Duong DM, Yin L, Trautwig AN, Guo Q, Xu K, Ping L, Reddy JS, Allen M, Quicksall Z, ... ... Golde TE, et al. Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity. Biorxiv : the Preprint Server For Biology. PMID 38712030 DOI: 10.1101/2024.04.22.590547 |
0.734 |
|
| 2024 |
Yang F, Beltran-Lobo P, Sung K, Goldrick C, Croft CL, Nishimura A, Hedges E, Mahiddine F, Troakes C, Golde TE, Perez-Nievas BG, Hanger DP, Noble W, Jimenez-Sanchez M. Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection. Science Advances. 10: eadk9884. PMID 38507480 DOI: 10.1126/sciadv.adk9884 |
0.807 |
|
| 2024 |
Guo Q, Ping L, Dammer EB, Yin L, Xu K, Shantaraman A, Fox EJ, Golde TE, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research Square. PMID 38464223 DOI: 10.21203/rs.3.rs-3933136/v1 |
0.314 |
|
| 2024 |
Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, ... Golde TE, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099 |
0.358 |
|
| 2023 |
Golde TE, Levey AI. Immunotherapies for Alzheimer's disease. Science (New York, N.Y.). 382: 1242-1244. PMID 38096276 DOI: 10.1126/science.adj9255 |
0.347 |
|
| 2023 |
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips JL, Iturbe A, Erqiuzi A, Moore BD, Ryu D, Natu A, ... ... Golde TE, et al. Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38076912 DOI: 10.1101/2023.11.29.568318 |
0.772 |
|
| 2023 |
Moore BD, Ran Y, Goodwin MS, Komatineni K, McFarland KN, Dillon K, Charles C, Ryu D, Liu X, Prokop S, Giasson BI, Golde TE, Levites Y. A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aβ scFvs: Applications for gene therapies. Molecular Therapy. Methods & Clinical Development. 31: 101146. PMID 38027063 DOI: 10.1016/j.omtm.2023.101146 |
0.604 |
|
| 2023 |
Min Y, Wang X, İş Ö, Patel TA, Gao J, Reddy JS, Quicksall ZS, Nguyen T, Lin S, Tutor-New FQ, Chalk JL, Mitchell AO, Crook JE, Nelson PT, Van Eldik LJ, ... Golde TE, et al. Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy. Nature Communications. 14: 6801. PMID 37919278 DOI: 10.1038/s41467-023-42626-3 |
0.508 |
|
| 2023 |
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp MD, Jimenez-Sanchez M, Perkinton MS, Kassiou M, Golde TE, Hanger DP, Verkhratsky A, Perez-Nievas BG, Noble W. P2XR influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes. Brain, Behavior, and Immunity. 114: 414-429. PMID 37716378 DOI: 10.1016/j.bbi.2023.09.011 |
0.816 |
|
| 2022 |
Croft CL, Paterno G, Vause AR, Rowe LA, Ryu DH, Goodwin MS, Moran CA, Cruz PE, Giasson BI, Golde TE. Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance. Npj Parkinson's Disease. 8: 173. PMID 36535953 DOI: 10.1038/s41531-022-00434-4 |
0.693 |
|
| 2022 |
Khalil B, Chhangani D, Wren MC, Smith CL, Lee JH, Li X, Puttinger C, Tsai CW, Fortin G, Morderer D, Gao J, Liu F, Lim CK, Chen J, Chou CC, ... ... Golde TE, et al. Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy. Molecular Neurodegeneration. 17: 80. PMID 36482422 DOI: 10.1186/s13024-022-00585-1 |
0.709 |
|
| 2022 |
Chen K, Martens YA, Meneses A, Ryu DH, Lu W, Raulin AC, Li F, Zhao J, Chen Y, Jin Y, Linares C, Goodwin M, Li Y, Liu CC, Kanekiyo T, ... ... Golde TE, et al. LRP1 is a neuronal receptor for α-synuclein uptake and spread. Molecular Neurodegeneration. 17: 57. PMID 36056345 DOI: 10.1186/s13024-022-00560-w |
0.414 |
|
| 2022 |
Ibanez KR, McFarland KN, Phillips J, Allen M, Lessard CB, Zobel L, De La Cruz EG, Shah S, Vo Q, Wang X, Quicksall Z, Ryu D, Funk C, Ertekin-Taner N, Prokop S, ... Golde TE, et al. Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways. Alzheimer's Research & Therapy. 14: 104. PMID 35897046 DOI: 10.1186/s13195-022-01044-1 |
0.758 |
|
| 2022 |
Xia Y, Prokop S, Bell BM, Gorion KM, Croft CL, Nasif L, Xu G, Riffe CJ, Manaois AN, Strang KH, Quintin SS, Paterno G, Tansey MG, Borchelt DR, Golde TE, et al. Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice. Communications Biology. 5: 446. PMID 35550593 DOI: 10.1038/s42003-022-03373-1 |
0.818 |
|
| 2022 |
Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C, Fromholt S, Janus C, Prokop S, Dickson D, Lewis J, Giasson BI, Golde TE, et al. Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts. Free Neuropathology. 3. PMID 35494163 DOI: 10.17879/freeneuropathology-2022-3766 |
0.828 |
|
| 2022 |
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW, Martin ER, Naj AC, Ertekin-Taner N, Golde TE, Hood L, et al. Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. Scientific Reports. 12: 6117. PMID 35413975 DOI: 10.1038/s41598-022-09825-2 |
0.53 |
|
| 2022 |
Marino M, Zhou L, Rincon MY, Callaerts-Vegh Z, Verhaert J, Wahis J, Creemers E, Yshii L, Wierda K, Saito T, Marneffe C, Voytyuk I, Wouters Y, Dewilde M, Duqué SI, ... ... Golde TE, et al. AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model. Embo Molecular Medicine. 14: e09824. PMID 35352880 DOI: 10.15252/emmm.201809824 |
0.329 |
|
| 2022 |
Aravindraja C, Sakthivel R, Liu X, Goodwin M, Veena P, Godovikova V, Fenno JC, Levites Y, Golde TE, Kesavalu L. Intracerebral but Not Peripheral Infection of Live Exacerbates Alzheimer's Disease Like Amyloid Pathology in APP-TgCRND8 Mice. International Journal of Molecular Sciences. 23. PMID 35328748 DOI: 10.3390/ijms23063328 |
0.38 |
|
| 2022 |
Golde TE. Alzheimer's disease - the journey of a healthy brain into organ failure. Molecular Neurodegeneration. 17: 18. PMID 35248124 DOI: 10.1186/s13024-022-00523-1 |
0.361 |
|
| 2022 |
Golde TE. Disease-Modifying Therapies for Alzheimer's Disease: More Questions than Answers. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 209-227. PMID 35229269 DOI: 10.1007/s13311-022-01201-2 |
0.353 |
|
| 2022 |
Golde TE. Disease-Modifying Therapies for Alzheimer's Disease: More Questions than Answers. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 209-227. PMID 35229269 DOI: 10.1007/s13311-022-01201-2 |
0.353 |
|
| 2022 |
Golde TE. Disease-Modifying Therapies for Alzheimer's Disease: More Questions than Answers. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 209-227. PMID 35229269 DOI: 10.1007/s13311-022-01201-2 |
0.353 |
|
| 2021 |
Wang X, Allen M, İş Ö, Reddy JS, Tutor-New FQ, Castanedes Casey M, Carrasquillo MM, Oatman SR, Min Y, Asmann YW, Funk C, Nguyen T, Ho CC, Malphrus KG, Seyfried NT, ... ... Golde TE, et al. Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions. The Journal of Clinical Investigation. PMID 34813500 DOI: 10.1172/JCI149904 |
0.676 |
|
| 2021 |
McFarland KN, Ceballos C, Rosario A, Ladd T, Moore B, Golde G, Wang X, Allen M, Ertekin-Taner N, Funk CC, Robinson M, Baloni P, Rappaport N, Chakrabarty P, Golde TE. Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo. Life Science Alliance. 4. PMID 34127518 DOI: 10.26508/lsa.202101108 |
0.587 |
|
| 2021 |
Levites Y, Funk C, Wang X, Chakrabarty P, McFarland KN, Bramblett B, O'Neal V, Liu X, Ladd T, Robinson M, Allen M, Carrasquillo MM, Dickson D, Cruz P, Ryu D, ... ... Golde TE, et al. Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy. Molecular Neurodegeneration. 16: 32. PMID 33957936 DOI: 10.1186/s13024-021-00453-4 |
0.582 |
|
| 2021 |
Croft CL, Goodwin MS, Ryu DH, Lessard CB, Tejeda G, Marrero M, Vause AR, Paterno G, Cruz PE, Lewis J, Giasson BI, Golde TE. Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions. Acta Neuropathologica. PMID 33496840 DOI: 10.1007/s00401-021-02264-9 |
0.746 |
|
| 2021 |
Li HD, Funk CC, McFarland K, Dammer EB, Allen M, Carrasquillo MM, Levties Y, Chakrabarty P, Burgess JD, Wang X, Dickson D, Seyfried NT, Duong DM, Lah JJ, Younkin SG, ... ... Golde TE, et al. Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480174 DOI: 10.1002/alz.12254 |
0.684 |
|
| 2020 |
Barker W, Quinonez C, Greig MT, Behar R, Chirinos C, Rodriguez RA, Rosselli M, Rodriguez MJ, Cid RC, Rundek T, McFarland K, Hanson K, Smith G, DeKosky S, Vaillancourt D, ... ... Golde T, et al. Utility of Plasma Neurofilament Light in the 1Florida Alzheimer's Disease Research Center (ADRC). Journal of Alzheimer's Disease : Jad. PMID 33216030 DOI: 10.3233/JAD-200901 |
0.463 |
|
| 2020 |
Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, ... ... Golde TE, et al. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. Jama Neurology. PMID 33074286 DOI: 10.1001/jamaneurol.2020.3536 |
0.51 |
|
| 2020 |
De Mena L, Smith MA, Martin J, Dunton KL, Ceballos-Diaz C, Jansen-West KR, Cruz PE, Dillon KD, Rincon-Limas DE, Golde TE, Moore BD, Levites Y. Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila. Alzheimer's Research & Therapy. 12: 132. PMID 33069251 DOI: 10.1186/s13195-020-00698-z |
0.377 |
|
| 2020 |
Funk CC, Casella AM, Jung S, Richards MA, Rodriguez A, Shannon P, Donovan-Maiye R, Heavner B, Chard K, Xiao Y, Glusman G, Ertekin-Taner N, Golde TE, Toga A, Hood L, et al. Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types. Cell Reports. 32: 108029. PMID 32814038 DOI: 10.1016/J.Celrep.2020.108029 |
0.422 |
|
| 2020 |
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Golde TE, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908 |
0.599 |
|
| 2020 |
Liu G, Fiock KL, Levites Y, Golde TE, Hefti MM, Lee G. Fyn depletion ameliorates tau-induced neuropathology. Acta Neuropathologica Communications. 8: 108. PMID 32665013 DOI: 10.1186/S40478-020-00979-6 |
0.38 |
|
| 2020 |
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Golde TE, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6 |
0.582 |
|
| 2020 |
Xu G, Fromholt SE, Chakrabarty P, Zhu F, Liu X, Pace MC, Koh J, Golde TE, Levites Y, Lewis J, Borchelt DR. Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis. Acta Neuropathologica Communications. 8: 43. PMID 32252825 DOI: 10.1186/S40478-020-00911-Y |
0.422 |
|
| 2020 |
Itzhaki RF, Golde TE, Heneka MT, Readhead B. Do infections have a role in the pathogenesis of Alzheimer disease? Nature Reviews. Neurology. PMID 32152461 DOI: 10.1038/S41582-020-0323-9 |
0.304 |
|
| 2020 |
Goodwin MS, Croft CL, Futch HS, Ryu D, Ceballos-Diaz C, Liu X, Paterno G, Mejia C, Deng D, Menezes K, Londono L, Arjona K, Parianos M, Truong V, Rostonics E, ... ... Golde TE, et al. Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS. Molecular Neurodegeneration. 15: 15. PMID 32122372 DOI: 10.1186/S13024-020-00361-Z |
0.675 |
|
| 2020 |
Koller EJ, Gonzalez De La Cruz E, Weinrich M, Williams T, Cruz PE, Ryu D, Golde TE, Sullivan PM, Lewis J, Borchelt DR, Chakrabarty P. Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy. Molecular Neurobiology. PMID 31903524 DOI: 10.1007/S12035-019-01859-4 |
0.388 |
|
| 2019 |
Croft CL, Futch HS, Moore BD, Golde TE. Organotypic brain slice cultures to model neurodegenerative proteinopathies. Molecular Neurodegeneration. 14: 45. PMID 31791377 DOI: 10.1186/S13024-019-0346-0 |
0.733 |
|
| 2019 |
Forner S, Martini AC, Prieto GA, Dang CT, Rodriguez-Ortiz CJ, Reyes-Ruiz JM, Trujillo-Estrada L, da Cunha C, Andrews EJ, Phan J, Vu Ha J, Chang AVZD, Levites Y, Cruz PE, Ager R, ... ... Golde T, et al. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific Reports. 9: 15936. PMID 31685865 DOI: 10.1038/S41598-019-52324-0 |
0.458 |
|
| 2019 |
Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR, Nosacka RL, Goodwin MS, Ran Y, Cruz PE, Ryu DH, Croft CL, Levites Y, ... ... Golde TE, et al. An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes. The Journal of Experimental Medicine. PMID 31467037 DOI: 10.1084/Jem.20190430 |
0.682 |
|
| 2019 |
Curiel Cid RE, Loewenstein DA, Rosselli M, Matias-Guiu JA, Piña D, Adjouadi M, Cabrerizo M, Bauer RM, Chan A, DeKosky ST, Golde T, Greig-Custo MT, Lizarraga G, Peñate A, Duara R. A cognitive stress test for prodromal Alzheimer's disease: Multiethnic generalizability. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 550-559. PMID 31417955 DOI: 10.1016/J.Dadm.2019.05.003 |
0.334 |
|
| 2019 |
Koller EJ, De La Cruz EG, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P. Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy. Human Molecular Genetics. PMID 31261380 DOI: 10.1093/Hmg/Ddz151 |
0.355 |
|
| 2019 |
Deyts C, Clutter M, Pierce N, Chakrabarty P, Ladd TB, Goddi A, Rosario AM, Cruz P, Vetrivel K, Wagner SL, Thinakaran G, Golde TE, Parent AT. APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model. Cell Reports. 27: 1345-1355.e6. PMID 31042463 DOI: 10.1016/J.Celrep.2019.03.087 |
0.388 |
|
| 2019 |
Duara R, Loewenstein DA, Lizarraga G, Adjouadi M, Barker WW, Greig-Custo MT, Rosselli M, Penate A, Shea YF, Behar R, Ollarves A, Robayo C, Hanson K, Marsiske M, Burke S, ... ... Golde T, et al. Effect of age, ethnicity, sex, cognitive status and APOE genotype on amyloid load and the threshold for amyloid positivity. Neuroimage. Clinical. 22: 101800. PMID 30991618 DOI: 10.1016/J.Nicl.2019.101800 |
0.57 |
|
| 2019 |
Croft CL, Cruz PE, Ryu DH, Ceballos-Diaz C, Strang KH, Woody BM, Lin WL, Deture M, Rodríguez-Lebrón E, Dickson DW, Chakrabarty P, Levites Y, Giasson BI, Golde TE. rAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies. The Journal of Experimental Medicine. PMID 30770411 DOI: 10.1084/Jem.20182184 |
0.757 |
|
| 2019 |
Strang KH, Golde TE, Giasson BI. MAPT mutations, tauopathy, and mechanisms of neurodegeneration. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30742061 DOI: 10.1038/S41374-019-0197-X |
0.318 |
|
| 2019 |
Duara R, Loewenstein DA, Lizarraga G, Adjouadi M, Barker WW, Greig-Custo MT, Rosselli M, Curiel RE, Hanson K, Marsiske M, Ertekin-Taner N, Vaillancourt D, DeKosky S, de Santi S, Golde TE. P2-427: THE RELATIONSHIP BETWEEN HISPANIC ETHNICITY, AMYLOID LOAD AND APOE4 CARRIER STATUS Alzheimer's & Dementia. 15: P775-P776. DOI: 10.1016/J.Jalz.2019.06.2834 |
0.498 |
|
| 2018 |
Strang KH, Sorrentino ZA, Riffe CJ, Gorion KM, Vijayaraghavan N, Golde TE, Giasson BI. Phosphorylation of serine 305 in tau inhibits aggregation. Neuroscience Letters. 692: 187-192. PMID 30423399 DOI: 10.1016/J.Neulet.2018.11.011 |
0.305 |
|
| 2018 |
Lessard CB, Malnik SL, Zhou Y, Ladd TB, Cruz PE, Ran Y, Mahan TE, Chakrabaty P, Holtzman DM, Ulrich JD, Colonna M, Golde TE. High-affinity interactions and signal transduction between Aβ oligomers and TREM2. Embo Molecular Medicine. PMID 30341064 DOI: 10.15252/Emmm.201809027 |
0.502 |
|
| 2018 |
Audrain M, Haure-Mirande JV, Wang M, Kim SH, Fanutza T, Chakrabarty P, Fraser P, St George-Hyslop PH, Golde TE, Blitzer RD, Schadt EE, Zhang B, Ehrlich ME, Gandy S. Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau. Molecular Psychiatry. PMID 30283031 DOI: 10.1038/S41380-018-0258-3 |
0.305 |
|
| 2018 |
Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, ... ... Golde TE, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. The Journal of Experimental Medicine. PMID 30158114 DOI: 10.1084/Jem.20180484 |
0.694 |
|
| 2018 |
Allen M, Wang X, Serie DJ, Strickland SL, Burgess JD, Koga S, Younkin CS, Nguyen TT, Malphrus KG, Lincoln SJ, Alamprese M, Zhu K, Chang R, Carrasquillo MM, Kouri N, ... ... Golde TE, et al. Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy. Acta Neuropathologica. PMID 30136084 DOI: 10.1007/S00401-018-1900-5 |
0.644 |
|
| 2018 |
Croft CL, Moore BD, Ran Y, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Novel monoclonal antibodies targeting the microtubule-binding domain of human tau. Plos One. 13: e0195211. PMID 29608591 DOI: 10.1371/Journal.Pone.0195211 |
0.754 |
|
| 2018 |
Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI. Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies. The Journal of Biological Chemistry. 293: 4579. PMID 29572329 DOI: 10.1074/jbc.AAC118.002657 |
0.729 |
|
| 2018 |
Chung J, Zhang X, Allen M, Wang X, Ma Y, Beecham G, Montine TJ, Younkin SG, Dickson DW, Golde TE, Price ND, Ertekin-Taner N, Lunetta KL, Mez J, et al. Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Alzheimer's Research & Therapy. 10: 22. PMID 29458411 DOI: 10.1186/S13195-018-0349-Z |
0.658 |
|
| 2018 |
Ridge PG, Karch CM, Hsu S, Arano I, Teerlink CC, Ebbert MTW, Murcia JDG, Farnham JM, Damato AR, Allen M, Wang X, Harari O, Fernandez VM, Guerreiro R, Bras J, ... ... Golde TE, et al. Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience. Genome Medicine. 10: 4. PMID 29329552 DOI: 10.1186/S13073-018-0516-7 |
0.647 |
|
| 2017 |
Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI. Distinct differences in prion-like seeding and aggregation between tau protein variants provide mechanistic insights into tauopathies. The Journal of Biological Chemistry. PMID 29259137 DOI: 10.1074/Jbc.M117.815357 |
0.758 |
|
| 2017 |
Moore BD, Martin J, de Mena L, Sanchez J, Cruz PE, Ceballos-Diaz C, Ladd TB, Ran Y, Levites Y, Kukar TL, Kurian JJ, McKenna R, Koo EH, Borchelt DR, Janus C, ... ... Golde TE, et al. Short Aβ peptides attenuate Aβ42 toxicity in vivo. The Journal of Experimental Medicine. PMID 29208777 DOI: 10.1084/Jem.20170600 |
0.733 |
|
| 2017 |
Ridge PG, Karch CM, Hsu S, Arano I, Teerlink CC, Ebbert MTW, Gonzalez Murcia JD, Farnham JM, Damato AR, Allen M, Wang X, Harari O, Fernandez VM, Guerreiro R, Bras J, ... ... Golde TE, et al. Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience. Genome Medicine. 9: 100. PMID 29183403 DOI: 10.1186/S13073-017-0486-1 |
0.648 |
|
| 2017 |
Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, ... ... Golde TE, et al. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29107053 DOI: 10.1016/J.Jalz.2017.09.012 |
0.679 |
|
| 2017 |
Strang KH, Goodwin MS, Riffe C, Moore BD, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau. Acta Neuropathologica Communications. 5: 58. PMID 28760159 DOI: 10.1186/S40478-017-0458-0 |
0.332 |
|
| 2017 |
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Golde TE, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
0.626 |
|
| 2017 |
Futch HS, Croft CL, Truong VQ, Krause EG, Golde TE. Targeting psychologic stress signaling pathways in Alzheimer's disease. Molecular Neurodegeneration. 12: 49. PMID 28633663 DOI: 10.1186/S13024-017-0190-Z |
0.756 |
|
| 2017 |
Prasad T, Zhu P, Verma A, Chakrabarty P, Rosario AM, Golde TE, Li Q. Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice. Scientific Reports. 7: 3222. PMID 28607377 DOI: 10.1038/S41598-017-03397-2 |
0.393 |
|
| 2017 |
Loewenstein DA, Curiel RE, DeKosky S, Rosselli M, Bauer R, Grieg-Custo M, Penate A, Li C, Lizagarra G, Golde T, Adjouadi M, Duara R. Recovery from Proactive Semantic Interference and MRI Volume: A Replication and Extension Study. Journal of Alzheimer's Disease : Jad. PMID 28598850 DOI: 10.3233/Jad-170276 |
0.424 |
|
| 2017 |
McFarland NR, McFarland KN, Golde TE. Parkinson Disease and Autoimmune Disorders-What Can We Learn From Genome-wide Pleiotropy? Jama Neurology. PMID 28586798 DOI: 10.1001/Jamaneurol.2017.0843 |
0.554 |
|
| 2017 |
Croft CL, Cruz PE, Goodwin MS, Ceballos-Diaz C, Strang K, Chakrabarty P, Levites Y, Giasson BI, Golde TE. [P4-094]: TARGETING TAU AGGREGATION IN BRAIN SLICE CULTURE MODELS OF TAUOPATHIES Alzheimer's & Dementia. 13: P1294-P1294. DOI: 10.1016/J.Jalz.2017.06.1959 |
0.725 |
|
| 2016 |
Carrasquillo MM, Allen M, Burgess JD, Wang X, Strickland SL, Aryal S, Siuda J, Kachadoorian ML, Medway C, Younkin CS, Nair A, Wang C, Chanana P, Serie D, Nguyen T, ... ... Golde TE, et al. A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27939925 DOI: 10.1016/J.Jalz.2016.10.005 |
0.639 |
|
| 2016 |
Allen M, Carrasquillo MM, Funk C, Heavner BD, Zou F, Younkin CS, Burgess JD, Chai HS, Crook J, Eddy JA, Li H, Logsdon B, Peters MA, Dang KK, Wang X, ... ... Golde TE, et al. Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases. Scientific Data. 3: 160089. PMID 27727239 DOI: 10.1038/Sdata.2016.89 |
0.663 |
|
| 2016 |
Fernandez-Funez P, Sanchez-Garcia J, de Mena L, Zhang Y, Levites Y, Khare S, Golde TE, Rincon-Limas DE. Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 27531960 DOI: 10.1073/Pnas.1608045113 |
0.367 |
|
| 2016 |
Park SA, Chevallier N, Tejwani K, Hung MM, Maruyama H, Golde TE, Koo EH. Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice. Biochemical and Biophysical Research Communications. PMID 27425247 DOI: 10.1016/J.Bbrc.2016.07.015 |
0.414 |
|
| 2016 |
Golde TE. Alzheimer disease: Host immune defence, amyloid-β peptide and Alzheimer disease. Nature Reviews. Neurology. PMID 27418376 DOI: 10.1038/nrneurol.2016.105 |
0.322 |
|
| 2016 |
Golde TE. Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies. Journal of Neurochemistry. PMID 27145445 DOI: 10.1111/jnc.13583 |
0.355 |
|
| 2016 |
Allen M, Burgess JD, Ballard T, Serie D, Wang X, Younkin CS, Sun Z, Kouri N, Baheti S, Wang C, Carrasquillo MM, Nguyen T, Lincoln S, Malphrus K, Murray M, ... Golde TE, et al. Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci. Acta Neuropathologica. PMID 27115769 DOI: 10.1007/S00401-016-1576-7 |
0.575 |
|
| 2016 |
DeKosky ST, Golde T. Cerebrospinal Biomarkers in Alzheimer Disease-Potential Roles as Markers of Prognosis and Neuroplasticity. Jama Neurology. PMID 27019279 DOI: 10.1001/Jamaneurol.2016.0090 |
0.452 |
|
| 2016 |
Golde TE, Ertekin-Taner N, Chakrabarty P, Allen M, Carrasquillo MM, Dickson DW, Younkin SG, Levites Y, Price ND, Funk C, Heavner BD, Logsdon B, Mangravite LM, Li H, Burgess JD, et al. F2-01-04: From Systems Level Transcriptomics to new Immune Targets for Alzheimer’s Disease Alzheimer's & Dementia. 12: P215-P216. DOI: 10.1016/J.Jalz.2016.06.383 |
0.57 |
|
| 2015 |
Xu G, Ran Y, Fromholt SE, Fu C, Yachnis AT, Golde TE, Borchelt DR. Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathologica Communications. 3: 72. PMID 26566997 DOI: 10.1186/S40478-015-0252-9 |
0.376 |
|
| 2015 |
Fernandez-Funez P, Zhang Y, Sanchez-Garcia J, de Mena L, Khare S, Golde TE, Levites Y, Rincon-Limas DE. Anti-Aβ single chain variable fragment antibodies exert synergistic neuroprotective activities in Drosophila models of Alzheimer's disease. Human Molecular Genetics. PMID 26253732 DOI: 10.1093/Hmg/Ddv321 |
0.343 |
|
| 2015 |
Ceballos-Diaz C, Rosario AM, Park HJ, Chakrabarty P, Sacino A, Cruz PE, Siemienski Z, Lara N, Moran C, Ravelo N, Golde TE, McFarland NR. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice. Molecular Neurodegeneration. 10: 25. PMID 26152284 DOI: 10.1186/S13024-015-0026-7 |
0.616 |
|
| 2015 |
Park HJ, Ran Y, Jung JI, Holmes O, Price AR, Smithson L, Ceballos-Diaz C, Han C, Wolfe MS, Daaka Y, Ryabinin AE, Kim SH, Hauger RL, Golde TE, Felsenstein KM. The stress response neuropeptide CRF increases amyloid-β production by regulating γ-secretase activity. The Embo Journal. 34: 1674-86. PMID 25964433 DOI: 10.15252/Embj.201488795 |
0.32 |
|
| 2015 |
Levites Y, O'Nuallain B, Puligedda RD, Ondrejcak T, Adekar SP, Chen C, Cruz PE, Rosario AM, Macy S, Mably AJ, Walsh DM, Vidal R, Solomon A, Brown D, Rowan MJ, ... Golde TE, et al. A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6265-76. PMID 25904780 DOI: 10.1523/Jneurosci.5109-14.2015 |
0.397 |
|
| 2015 |
Ceballos-Diaz C, Rosario AM, Park HJ, Chakrabarty P, Sacino A, Cruz PE, Siemienski Z, Lara N, Moran C, Ravelo N, Golde TE, McFarland NR. Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice Molecular Neurodegeneration. DOI: 10.1186/s13024-015-0026-7 |
0.57 |
|
| 2015 |
Prasad T, Zhu P, Verma A, Chakrabarty P, Rosario AM, Golde TE, Li Q. 391. Increased Levels of Amyloid β Peptides in RPE via AAV-Mediated Gene Transfer Mimics AMD-Like Pathology in Mice Molecular Therapy. 23: S155. DOI: 10.1016/S1525-0016(16)34000-X |
0.382 |
|
| 2015 |
Golde T, Levites Y, Cruz PE, Rosario AM, Chakrabarty P, Moran C, Liu X, Ceballos-Diaz C, Moore B, Price ND, Funk C. O1-11-03: Modulating chemokine signaling in preclinical Alzheimer's disease models Alzheimer's & Dementia. 11: P157-P157. DOI: 10.1016/J.Jalz.2015.07.089 |
0.347 |
|
| 2015 |
Moore B, Martin J, de Mena L, Sanchez J, Rincon-Limas DE, Fernandez-Funez P, Golde T. P1-084: Exploring the toxicity of short amyloid-beta peptides in vivo Alzheimer's & Dementia. 11: P371-P371. DOI: 10.1016/J.Jalz.2015.06.281 |
0.379 |
|
| 2014 |
Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL. Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3826-40. PMID 24623762 DOI: 10.1523/Jneurosci.5171-13.2014 |
0.372 |
|
| 2014 |
Jung JI, Ran Y, Cruz PE, Rosario AM, Ladd TB, Kukar TL, Koo EH, Felsenstein KM, Golde TE. Complex relationships between substrate sequence and sensitivity to alterations in γ-secretase processivity induced by γ-secretase modulators. Biochemistry. 53: 1947-57. PMID 24620716 DOI: 10.1021/Bi401521T |
0.714 |
|
| 2014 |
Golde TE. Open questions for Alzheimer's disease immunotherapy. Alzheimer's Research & Therapy. 6: 3. PMID 24393284 DOI: 10.1186/alzrt233 |
0.348 |
|
| 2014 |
Chakrabarty P, Tianbai L, Moore B, Rosario A, Cruz P, Ladd T, Ceballos-Diaz C, Golde T. P1-095: MODULATING INNATE IMMUNITY IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P336-P337. DOI: 10.1016/J.Jalz.2014.05.331 |
0.342 |
|
| 2013 |
Golde TE, Lewis J, McFarland NR. Anti-tau antibodies: hitting the target. Neuron. 80: 254-6. PMID 24139027 DOI: 10.1016/J.Neuron.2013.10.009 |
0.624 |
|
| 2013 |
Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, ... ... Golde TE, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/Jci69003 |
0.411 |
|
| 2013 |
Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. γ-Secretase inhibitors and modulators. Biochimica Et Biophysica Acta. 1828: 2898-907. PMID 23791707 DOI: 10.1016/J.Bbamem.2013.06.005 |
0.363 |
|
| 2013 |
Rutherford NJ, Lewis J, Clippinger AK, Thomas MA, Adamson J, Cruz PE, Cannon A, Xu G, Golde TE, Shaw G, Borchelt DR, Giasson BI. Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions. Brain Research. 1524: 62-73. PMID 23774650 DOI: 10.1016/J.Brainres.2013.06.006 |
0.325 |
|
| 2013 |
Jung JI, Ladd TB, Kukar T, Price AR, Moore BD, Koo EH, Golde TE, Felsenstein KM. Steroids as γ-secretase modulators. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3775-85. PMID 23716494 DOI: 10.1096/Fj.12-225649 |
0.683 |
|
| 2013 |
Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM. Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (New York, N.Y.). 340: 924-d. PMID 23704553 DOI: 10.1126/science.1234089 |
0.381 |
|
| 2013 |
Golde TE, Streit WJ, Chakrabarty P. Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease. Alzheimer's Research & Therapy. 5: 24. PMID 23692967 DOI: 10.1186/Alzrt178 |
0.332 |
|
| 2013 |
Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, et al. Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy. Acta Neuropathologica. 126: 39-50. PMID 23666556 DOI: 10.1007/S00401-013-1123-8 |
0.358 |
|
| 2013 |
Kim J, Chakrabarty P, Hanna A, March A, Dickson DW, Borchelt DR, Golde T, Janus C. Normal cognition in transgenic BRI2-Aβ mice. Molecular Neurodegeneration. 8: 15. PMID 23663320 DOI: 10.1186/1750-1326-8-15 |
0.651 |
|
| 2013 |
Melnikova T, Fromholt S, Kim H, Lee D, Xu G, Price A, Moore BD, Golde TE, Felsenstein KM, Savonenko A, Borchelt DR. Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3765-79. PMID 23447589 DOI: 10.1523/Jneurosci.4251-12.2013 |
0.34 |
|
| 2013 |
Chu J, Li JG, Ceballos-Diaz C, Golde T, Praticò D. The influence of 5-lipoxygenase on Alzheimer's disease-related tau pathology: in vivo and in vitro evidence. Biological Psychiatry. 74: 321-8. PMID 23352590 DOI: 10.1016/J.Biopsych.2012.12.012 |
0.491 |
|
| 2013 |
Golde TE, Felsenstein K, Chakrabarty P, Li A, Moore B, In JJ, Cruz P, Price A, Borchelt D, Janus C, Cebballos-Diaz C, Rosario A. Harnessing endogenous pathways and metabolites to treat or prevent neurodegenerative disease Molecular Neurodegeneration. 8. DOI: 10.1186/1750-1326-8-S1-O36 |
0.323 |
|
| 2013 |
Blair L, Nordhues B, Hill S, Scaglione KM, O'Leary J, Breydo L, Bo Z, Li P, Wang L, Cotman C, Paulson H, Muschol M, Uversky V, Klengel T, Binder E, ... ... Golde T, et al. The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease Alzheimers & Dementia. 9: 173. DOI: 10.1016/J.Jalz.2013.05.279 |
0.438 |
|
| 2013 |
Pratico D, Golde T, Chu J. P4-024: Involvement of 5lipoxygenase in Alzheimer's disease tau neuropathology Alzheimer's & Dementia. 9: P713-P713. DOI: 10.1016/J.Jalz.2013.05.1412 |
0.435 |
|
| 2013 |
Sahara N, Levites Y, Sinyavskiy G, Rosario A, Cruz P, Golde T. O2-08-04: Extracellular versus intracellular anti-tau immunotherapy effects in rTg4510 tau transgenic mice Alzheimer's & Dementia. 9: P330-P331. DOI: 10.1016/J.Jalz.2013.04.180 |
0.358 |
|
| 2012 |
Verbeeck C, Deng Q, Dejesus-Hernandez M, Taylor G, Ceballos-Diaz C, Kocerha J, Golde T, Das P, Rademakers R, Dickson DW, Kukar T. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis. Molecular Neurodegeneration. 7: 53. PMID 23046583 DOI: 10.1186/1750-1326-7-53 |
0.687 |
|
| 2012 |
Park HJ, Shabashvili D, Nekorchuk MD, Shyqyriu E, Jung JI, Ladd TB, Moore BD, Felsenstein KM, Golde TE, Kim SH. Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP). The Journal of Biological Chemistry. 287: 40629-40. PMID 23043097 DOI: 10.1074/jbc.M112.418442 |
0.39 |
|
| 2012 |
Chu J, Giannopoulos PF, Ceballos-Diaz C, Golde TE, Praticò D. 5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease. Annals of Neurology. 72: 442-54. PMID 23034916 DOI: 10.1002/ana.23642 |
0.414 |
|
| 2012 |
Cai J, Qi X, Kociok N, Skosyrski S, Emilio A, Ruan Q, Han S, Liu L, Chen Z, Bowes Rickman C, Golde T, Grant MB, Saftig P, Serneels L, de Strooper B, et al. β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment. Embo Molecular Medicine. 4: 980-91. PMID 22903875 DOI: 10.1002/Emmm.201101084 |
0.327 |
|
| 2012 |
Chen Y, Huang X, Zhang YW, Rockenstein E, Bu G, Golde TE, Masliah E, Xu H. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11390-5. PMID 22895721 DOI: 10.1523/Jneurosci.0757-12.2012 |
0.356 |
|
| 2012 |
Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of Aβ production prior to deposition results in sustained reduction of amyloid plaque pathology. Molecular Neurodegeneration. 7: 39. PMID 22892055 DOI: 10.1186/1750-1326-7-39 |
0.68 |
|
| 2012 |
Chakrabarty P, Tianbai L, Herring A, Ceballos-Diaz C, Das P, Golde TE. Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition. Molecular Neurodegeneration. 7: 36. PMID 22838967 DOI: 10.1186/1750-1326-7-36 |
0.392 |
|
| 2012 |
Hanna A, Iremonger K, Das P, Dickson D, Golde T, Janus C. Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis. Alzheimer's Research & Therapy. 4: 21. PMID 22697412 DOI: 10.1186/Alzrt124 |
0.366 |
|
| 2012 |
Moore BD, Chakrabarty P, Levites Y, Kukar TL, Baine AM, Moroni T, Ladd TB, Das P, Dickson DW, Golde TE. Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains. Alzheimer's Research & Therapy. 4: 18. PMID 22621179 DOI: 10.1186/Alzrt121 |
0.717 |
|
| 2012 |
Galasko D, Golde T, Wilcock G. Recent Alzheimer's disease research highlights. Alzheimer's Research & Therapy. 4: 14. PMID 22594696 DOI: 10.1186/Alzrt117 |
0.452 |
|
| 2012 |
Golde TE, Ran Y, Felsenstein KM. Shifting a complex debate on γ-secretase cleavage and Alzheimer's disease. The Embo Journal. 31: 2237-9. PMID 22505028 DOI: 10.1038/Emboj.2012.111 |
0.386 |
|
| 2012 |
Chu J, Giannopoulos PF, Ceballos-Diaz C, Golde TE, Pratico D. Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice. Molecular Neurodegeneration. 7: 1. PMID 22222029 DOI: 10.1186/1750-1326-7-1 |
0.422 |
|
| 2012 |
Felsenstein K, Jung J, Ladd T, Price A, Moore B, Tang Y, Shapiro G, Hochhaus G, Golde T. O1-11-03: Endogenous cholesterol metabolites as potential Alzheimer's therapeutics Alzheimer's & Dementia. 8: P104-P105. DOI: 10.1016/J.Jalz.2012.05.265 |
0.322 |
|
| 2012 |
Park H, Shults C, Shyqyriu E, Vaziri S, Felsenstein K, Ceballos-Diaz C, Ladd T, Jung J, Kim S, Golde T. P4-003: Corticotropin-releasing hormone alters Aβ42 production via gamma-secretase Alzheimer's & Dementia. 8: P639-P639. DOI: 10.1016/J.Jalz.2012.05.1704 |
0.325 |
|
| 2011 |
Sagi SA, Lessard CB, Winden KD, Maruyama H, Koo JC, Weggen S, Kukar TL, Golde TE, Koo EH. Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein. The Journal of Biological Chemistry. 286: 39794-803. PMID 21868380 DOI: 10.1074/Jbc.M111.277228 |
0.677 |
|
| 2011 |
Kukar TL, Ladd TB, Robertson P, Pintchovski SA, Moore B, Bann MA, Ren Z, Jansen-West K, Malphrus K, Eggert S, Maruyama H, Cottrell BA, Das P, Basi GS, Koo EH, ... Golde TE, et al. Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region. The Journal of Biological Chemistry. 286: 39804-12. PMID 21868378 DOI: 10.1074/Jbc.M111.274696 |
0.734 |
|
| 2011 |
Chakrabarty P, Ceballos-Diaz C, Lin WL, Beccard A, Jansen-West K, McFarland NR, Janus C, Dickson D, Das P, Golde TE. Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification. Nature Neuroscience. 14: 694-6. PMID 21572432 DOI: 10.1038/Nn.2829 |
0.563 |
|
| 2011 |
Wang A, Das P, Switzer RC, Golde TE, Jankowsky JL. Robust amyloid clearance in a mouse model of Alzheimer's disease provides novel insights into the mechanism of amyloid-beta immunotherapy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4124-36. PMID 21411653 DOI: 10.1523/JNEUROSCI.5077-10.2011 |
0.422 |
|
| 2011 |
Chakrabarty P, Herring A, Ceballos-Diaz C, Das P, Golde TE. Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo. Molecular Neurodegeneration. 6: 16. PMID 21324189 DOI: 10.1186/1750-1326-6-16 |
0.385 |
|
| 2011 |
Golde TE, Schneider LS, Koo EH. Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift. Neuron. 69: 203-13. PMID 21262461 DOI: 10.1016/J.Neuron.2011.01.002 |
0.349 |
|
| 2011 |
Chakrabarty P, Ceballos-Diaz C, Beccard A, Cruz P, Dickson D, Das P, Golde T. P2-326: Towards a comprehensive analysis of the role of inflammatory mediators on Alzheimer's like pathology in pre-clinical mouse models Alzheimer's & Dementia. 7: S413-S414. DOI: 10.1016/J.Jalz.2011.05.1202 |
0.37 |
|
| 2010 |
Meckler X, Roseman J, Das P, Cheng H, Pei S, Keat M, Kassarjian B, Golde TE, Parent AT, Thinakaran G. Reduced Alzheimer's disease ß-amyloid deposition in transgenic mice expressing S-palmitoylation-deficient APH1aL and nicastrin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16160-9. PMID 21123562 DOI: 10.1523/Jneurosci.4436-10.2010 |
0.379 |
|
| 2010 |
Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P. IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 5333-43. PMID 20368278 DOI: 10.4049/Jimmunol.0903382 |
0.402 |
|
| 2010 |
De Strooper B, Vassar R, Golde T. The secretases: enzymes with therapeutic potential in Alzheimer disease. Nature Reviews. Neurology. 6: 99-107. PMID 20139999 DOI: 10.1038/nrneurol.2009.218 |
0.398 |
|
| 2010 |
Chakrabarty P, Jansen-West K, Beccard A, Ceballos-Diaz C, Levites Y, Verbeeck C, Zubair AC, Dickson D, Golde TE, Das P. Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 548-59. PMID 19825975 DOI: 10.1096/Fj.09-141754 |
0.416 |
|
| 2010 |
Golde TE, Petrucelli L, Lewis J. Targeting Abeta and tau in Alzheimer's disease, an early interim report. Experimental Neurology. 223: 252-66. PMID 19716367 DOI: 10.1016/J.Expneurol.2009.07.035 |
0.455 |
|
| 2010 |
Wang A, Das P, Switzer RC, Golde TE, Jankowsky JL. O4-08-05: Robust Amyloid Clearance in a Mouse Model of AD Provides Novel Insights into the Mechanism of Abeta Immunotherapy Alzheimer's & Dementia. 6: e19-e19. DOI: 10.1016/j.jalz.2010.08.058 |
0.364 |
|
| 2010 |
Chakrabarty P, Beccard A, Cellallos-Diaz C, Golde T, Das P. P1-320: AAV-mediated expression of anti-inflammatory cytokines IL-10 and IL-4 significantly exacerbate amyloid pathology in the brains of APP TgCRND8 mice Alzheimer's & Dementia. 6: S266-S266. DOI: 10.1016/J.Jalz.2010.05.873 |
0.325 |
|
| 2010 |
Kukar T, Ladd T, Robertson P, Moore B, Jansen-West K, Eggert S, Koo E, Golde T. O2-03-01: Insight into the mechanism of gamma-secretase cleavage: Juxtamembrane amino acids are key to the length of secreted amyloid beta peptide Alzheimer's & Dementia. 6: S100-S100. DOI: 10.1016/J.Jalz.2010.05.314 |
0.691 |
|
| 2010 |
Abisambra JF, Blair LJ, Jones JR, Kraft C, Hill S, Rogers J, Koren J, Jinwal UK, Lawson L, Johnson AG, Jansen-West K, Muschol M, Banko J, Golde T, Weeber EJ, et al. P3-425: Chaperone-mediated modulation of tau aggregation correlates with modifications in tau pathology and synaptic plasticity Alzheimer's & Dementia. 6: S577-S577. DOI: 10.1016/J.Jalz.2010.05.1968 |
0.368 |
|
| 2009 |
Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2031-2040. PMID 28178451 DOI: 10.1038/mt.2009.174 |
0.429 |
|
| 2009 |
Sala Frigerio C, Kukar TL, Fauq A, Engel PC, Golde TE, Walsh DM. An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1. Biochemistry. 48: 10894-904. PMID 19821615 DOI: 10.1021/Bi901237K |
0.711 |
|
| 2009 |
Donnelly A, Galasko D, Golde T, Mulvany F, Wilcock G. Welcome to Alzheimer's research & therapy. Alzheimer's Research & Therapy. 1: 1. PMID 19671199 DOI: 10.1186/Alzrt1 |
0.354 |
|
| 2009 |
Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2031-40. PMID 19638957 DOI: 10.1038/Mt.2009.174 |
0.352 |
|
| 2009 |
Garcia-Alloza M, Subramanian M, Thyssen D, Borrelli LA, Fauq A, Das P, Golde TE, Hyman BT, Bacskai BJ. Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575. Molecular Neurodegeneration. 4: 19. PMID 19419556 DOI: 10.1186/1750-1326-4-19 |
0.392 |
|
| 2009 |
Golde TE, Kukar TL. Medicine. Avoiding unintended toxicity. Science (New York, N.Y.). 324: 603-4. PMID 19407192 DOI: 10.1126/science.1174267 |
0.6 |
|
| 2009 |
McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG. Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Disease. 34: 163-77. PMID 19320056 DOI: 10.1016/J.Nbd.2009.01.006 |
0.352 |
|
| 2009 |
Golde TE, Das P, Levites Y. Quantitative and mechanistic studies of Abeta immunotherapy. Cns & Neurological Disorders Drug Targets. 8: 31-49. PMID 19275635 DOI: 10.2174/187152709787601830 |
0.413 |
|
| 2008 |
Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proceedings of the National Academy of Sciences of the United States of America. 105: 10595-600. PMID 18647832 DOI: 10.1073/Pnas.0803671105 |
0.362 |
|
| 2008 |
Kukar TL, Ladd TB, Bann MA, Fraering PC, Narlawar R, Maharvi GM, Healy B, Chapman R, Welzel AT, Price RW, Moore B, Rangachari V, Cusack B, Eriksen J, Jansen-West K, ... ... Golde TE, et al. Substrate-targeting gamma-secretase modulators. Nature. 453: 925-9. PMID 18548070 DOI: 10.1038/Nature07055 |
0.807 |
|
| 2008 |
Kim J, Miller VM, Levites Y, West KJ, Zwizinski CW, Moore BD, Troendle FJ, Bann M, Verbeeck C, Price RW, Smithson L, Sonoda L, Wagg K, Rangachari V, Zou F, ... ... Golde TE, et al. BRI2 (ITM2b) inhibits Abeta deposition in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6030-6. PMID 18524908 DOI: 10.1523/Jneurosci.0891-08.2008 |
0.744 |
|
| 2008 |
Czirr E, Cottrell BA, Leuchtenberger S, Kukar T, Ladd TB, Esselmann H, Paul S, Schubenel R, Torpey JW, Pietrzik CU, Golde TE, Wiltfang J, Baumann K, Koo EH, Weggen S. Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase. The Journal of Biological Chemistry. 283: 17049-54. PMID 18426795 DOI: 10.1074/Jbc.M802912200 |
0.723 |
|
| 2008 |
Buxbaum JN, Ye Z, Reixach N, Friske L, Levy C, Das P, Golde T, Masliah E, Roberts AR, Bartfai T. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 2681-6. PMID 18272491 DOI: 10.1073/Pnas.0712197105 |
0.514 |
|
| 2008 |
Kukar T, Golde TE. Possible mechanisms of action of NSAIDs and related compounds that modulate gamma-secretase cleavage. Current Topics in Medicinal Chemistry. 8: 47-53. PMID 18220932 DOI: 10.2174/156802608783334042 |
0.717 |
|
| 2008 |
Golde TE. S2-02-05: Anti-abeta antibodies in Alzheimer's disease mouse models Alzheimer's & Dementia. 4: T125-T125. DOI: 10.1016/j.jalz.2008.05.280 |
0.307 |
|
| 2008 |
Zou F, Kim J, Miller VM, Levites Y, Ma L, Cangemi D, Bisceglio G, Younkin S, Pankratz VS, Petersen RC, Graff-Radford N, Dickson D, Rosenberry T, Golde T, Younkin SG. P3-276: BRI2 (ITM2B) shows genetic association with late-onset Alzheimer's disease Alzheimer's & Dementia. 4: T603-T603. DOI: 10.1016/J.Jalz.2008.05.1844 |
0.677 |
|
| 2008 |
Miller VM, Kim J, Zou F, Levites Y, Jansen-West K, Zwizinski CW, Moore BD, Troendle FJ, Bann M, Verbeeck C, Price R, Smithson L, Rangachari V, Sonoda L, Wagg K, ... ... Golde TE, et al. P2-347: BRI2 (ITM2B) inhibits Aβ deposition Alzheimer's & Dementia. 4: T474-T475. DOI: 10.1016/J.Jalz.2008.05.1424 |
0.661 |
|
| 2008 |
Kukar TL, Ladd TB, Bann MA, Fraering PC, Maharvi GM, Moore B, Rangachari V, Welzel A, Ye W, Sagi S, Cottrell BA, Torpey J, Rosenberry TL, Fauq A, Wolfe MS, ... ... Golde TE, et al. P2-338: Substrate-targeting gamma-secretase modulators Alzheimer's & Dementia. 4: T472-T472. DOI: 10.1016/J.Jalz.2008.05.1415 |
0.625 |
|
| 2008 |
Levites Y, Jansen K, Ceballos C, Golde TE. P2-303: Anti-amyloid single chain fragments as a tool to target Abeta deposition in APP mouse models Alzheimer's & Dementia. 4: T461-T461. DOI: 10.1016/J.Jalz.2008.05.1380 |
0.333 |
|
| 2007 |
Galasko DR, Graff-Radford N, May S, Hendrix S, Cottrell BA, Sagi SA, Mather G, Laughlin M, Zavitz KH, Swabb E, Golde TE, Murphy MP, Koo EH. Safety, tolerability, pharmacokinetics, and Abeta levels after short-term administration of R-flurbiprofen in healthy elderly individuals. Alzheimer Disease and Associated Disorders. 21: 292-9. PMID 18090435 DOI: 10.1097/Wad.0B013E31815D1048 |
0.379 |
|
| 2007 |
Kukar T, Prescott S, Eriksen JL, Holloway V, Murphy MP, Koo EH, Golde TE, Nicolle MM. Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice. Bmc Neuroscience. 8: 54. PMID 17650315 DOI: 10.1186/1471-2202-8-54 |
0.81 |
|
| 2007 |
Ostrowski SM, Wilkinson BL, Golde TE, Landreth G. Statins reduce amyloid-beta production through inhibition of protein isoprenylation. The Journal of Biological Chemistry. 282: 26832-44. PMID 17646164 DOI: 10.1074/Jbc.M702640200 |
0.346 |
|
| 2007 |
Lawlor PA, Bland RJ, Das P, Price RW, Holloway V, Smithson L, Dicker BL, During MJ, Young D, Golde TE. Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels. Molecular Neurodegeneration. 2: 11. PMID 17559680 DOI: 10.1186/1750-1326-2-11 |
0.407 |
|
| 2007 |
Kim J, Onstead L, Randle S, Price R, Smithson L, Zwizinski C, Dickson DW, Golde T, McGowan E. Abeta40 inhibits amyloid deposition in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 627-33. PMID 17234594 DOI: 10.1523/Jneurosci.4849-06.2007 |
0.743 |
|
| 2007 |
Golde TE. The pathogenesis of Alzheimer's disease and the role of Abeta42. Cns Spectrums. 12: 4-6. PMID 17192766 |
0.383 |
|
| 2007 |
Ahmed RR, Murphy MP, Rochette MJ, Golde TE. Beta‐secretase regulation in aging and disease The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a278-b |
0.316 |
|
| 2007 |
Golde TE. Chapter 1 Amyloid and Amyloid-Like Protein Aggregates in Neurodegenerative Disease Blue Books of Neurology. 30: 1-32. DOI: 10.1016/S1877-184X(09)70052-8 |
0.381 |
|
| 2007 |
Kennedy GJ, Golde TE, Tariot PN, Cummings JL. Amyloid-based interventions in Alzheimer's disease Cns Spectrums. 12: 1-14. |
0.319 |
|
| 2006 |
Golde TE, Dickson D, Hutton M. Filling the gaps in the abeta cascade hypothesis of Alzheimer's disease. Current Alzheimer Research. 3: 421-30. PMID 17168641 DOI: 10.2174/156720506779025189 |
0.449 |
|
| 2006 |
Levites Y, Jansen K, Smithson LA, Dakin R, Holloway VM, Das P, Golde TE. Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11923-8. PMID 17108166 DOI: 10.1523/Jneurosci.2795-06.2006 |
0.441 |
|
| 2006 |
Das P, Golde T. Dysfunction of TGF-beta signaling in Alzheimer's disease. The Journal of Clinical Investigation. 116: 2855-7. PMID 17080189 DOI: 10.1172/Jci30284 |
0.487 |
|
| 2006 |
Golde TE. Disease modifying therapy for AD? Journal of Neurochemistry. 99: 689-707. PMID 17076654 DOI: 10.1111/j.1471-4159.2006.04211.x |
0.387 |
|
| 2006 |
Levites Y, Smithson LA, Price RW, Dakin RS, Yuan B, Sierks MR, Kim J, McGowan E, Reed DK, Rosenberry TL, Das P, Golde TE. Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2576-8. PMID 17068112 DOI: 10.1096/Fj.06-6463Fje |
0.717 |
|
| 2006 |
Boeve BF, Baker M, Dickson DW, Parisi JE, Giannini C, Josephs KA, Hutton M, Pickering-Brown SM, Rademakers R, Tang-Wai D, Jack CR, Kantarci K, Shiung MM, Golde T, Smith GE, et al. Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic study. Brain : a Journal of Neurology. 129: 3103-14. PMID 17030535 DOI: 10.1093/Brain/Awl268 |
0.339 |
|
| 2006 |
Nyborg AC, Ladd TB, Jansen K, Kukar T, Golde TE. Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1671-9. PMID 16873890 DOI: 10.1096/Fj.06-5762Com |
0.636 |
|
| 2006 |
Murphy MP, Golde TE. Inclusion-body myositis and Alzheimer disease: two sides of the same coin, or different currencies altogether? Neurology. 66: S65-8. PMID 16432148 DOI: 10.1212/01.wnl.0000192108.02654.ac |
0.424 |
|
| 2006 |
Levites Y, Das P, Price RW, Rochette MJ, Kostura LA, McGowan EM, Murphy MP, Golde TE. Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. The Journal of Clinical Investigation. 116: 193-201. PMID 16341263 DOI: 10.1172/Jci25410 |
0.678 |
|
| 2006 |
Leuchtenberger S, Kummer MP, Kukar T, Czirr E, Teusch N, Sagi SA, Berdeaux R, Pietrzik CU, Ladd TB, Golde TE, Koo EH, Weggen S. Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42. Journal of Neurochemistry. 96: 355-65. PMID 16300630 DOI: 10.1111/J.1471-4159.2005.03553.X |
0.716 |
|
| 2006 |
Fowlkes KL, Mastrangelo MA, Narrow WC, Levites Y, Golde TE, Federoff HJ, Bowers WJ. 247. Devising Aβ-Specific Passive Immunization Strategies for Alzheimer's Disease Using rAAV Vector-Mediated scFv Antibody Delivery Molecular Therapy. 13: S94-S95. DOI: 10.1016/J.Ymthe.2006.08.274 |
0.377 |
|
| 2006 |
Duara R, Loewenstein DA, Lizarraga G, Adjouadi M, Barker WW, Greig-Custo MT, Penate A, Hanson K, Marsiske M, Burke SL, Ertekin-Taner N, Vaillancourt D, DeKosky S, de Santi S, Golde TE. P3-378: EFFECT OF AGE, GENDER, ETHNICITY, COGNITION AND APOE GENOTYPE ON AMYLOID LOAD AMONG NORMAL, MCI AND MILD DEMENTIA SUBJECTS USING [F-18] FLORBETABEN Alzheimer's & Dementia. 14: P1237-P1238. DOI: 10.1016/J.Jalz.2018.06.1740 |
0.481 |
|
| 2006 |
Kim J, Onstead L, Smithson L, Price R, Randle S, Yu C, Dickson D, Golde T, McGowan E. P1-113: The Abeta42/Abeta40 ratio, not total Abeta level, controls amyloid deposition in transgenic mice Alzheimer's & Dementia. 2: S128-S129. DOI: 10.1016/J.Jalz.2006.05.489 |
0.737 |
|
| 2006 |
Golde TE, Jansen KR, Nyborg AC, Das P, Chakrabarty P, Smithson LA, Kim J, Levties Y. P1-005: RAAV vectors to rapidly modify and model AD pathology in mice, rats, and guinea pigs Alzheimer's & Dementia. 2: S95-S95. DOI: 10.1016/J.Jalz.2006.05.380 |
0.553 |
|
| 2006 |
Janus C, Kim J, Hanna A, Wilson J, Price R, Dickson D, Golde T, McGowan E. O4-05-05: Dissociation between amyloid pathology and memory impairment Alzheimer's & Dementia. 2: S85-S86. DOI: 10.1016/J.Jalz.2006.05.331 |
0.665 |
|
| 2006 |
Kukar T, Ladd T, Bann M, Fraering P, Kache R, Fauq A, Wolfe M, Koo EH, Golde TE. P4-289: Mechanistic insights into the in vitro
and in vivo
modulation of Aβ42 levels and amyloid pathology by NSAIDS and related compounds Alzheimer's & Dementia. 2: S601-S602. DOI: 10.1016/J.Jalz.2006.05.2028 |
0.707 |
|
| 2006 |
Das P, Hrncic R, Golde T. P4-258: Heterologous amyloid vaccines induce a generic anti-amyloid response Alzheimer's & Dementia. 2: S592-S592. DOI: 10.1016/J.Jalz.2006.05.1997 |
0.357 |
|
| 2005 |
McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, Delucia M, Lin WL, Dolios G, Wang R, ... ... Golde T, et al. Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. Neuron. 47: 191-9. PMID 16039562 DOI: 10.1016/J.Neuron.2005.06.030 |
0.829 |
|
| 2005 |
Kukar T, Murphy MP, Eriksen JL, Sagi SA, Weggen S, Smith TE, Ladd T, Khan MA, Kache R, Beard J, Dodson M, Merit S, Ozols VV, Anastasiadis PZ, Das P, ... ... Golde TE, et al. Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production. Nature Medicine. 11: 545-50. PMID 15834426 DOI: 10.1038/Nm1235 |
0.822 |
|
| 2005 |
Golde TE. The Abeta hypothesis: leading us to rationally-designed therapeutic strategies for the treatment or prevention of Alzheimer disease. Brain Pathology (Zurich, Switzerland). 15: 84-7. PMID 15779241 |
0.441 |
|
| 2004 |
Akbari Y, Hitt BD, Murphy MP, Dagher NN, Tseng BP, Green KN, Golde TE, LaFerla FM. Presenilin regulates capacitative calcium entry dependently and independently of gamma-secretase activity. Biochemical and Biophysical Research Communications. 322: 1145-52. PMID 15336962 DOI: 10.1016/J.Bbrc.2004.07.136 |
0.308 |
|
| 2004 |
Pickford F, Onstead-Cardinale L, Eriksen J, Murphy P, Pritam D, Kim J, Dolios G, Wang R, Dickson DW, Golde T, McGowan E. P2-090 ABETA42 is required for amyloid deposition in transgenic mice Neurobiology of Aging. 25: S249. DOI: 10.1016/S0197-4580(04)80837-6 |
0.767 |
|
| 2004 |
Golde TE, Eriksen J, Nicolle M, Murphy MP, Kukar T, Monnier T, Prescott S, Wright S, Chevallier N, Sagi S, Das P, Koo EH. O3-06-02 Selective Abeta42 modifying agents: effects on Abeta deposition and behavior in TG2576 mice Neurobiology of Aging. 25: S64. DOI: 10.1016/S0197-4580(04)80215-X |
0.782 |
|
| 2003 |
Ramsden M, Nyborg AC, Murphy MP, Chang L, Stanczyk FZ, Golde TE, Pike CJ. Androgens modulate beta-amyloid levels in male rat brain. Journal of Neurochemistry. 87: 1052-5. PMID 14622134 DOI: 10.1046/J.1471-4159.2003.02114.X |
0.484 |
|
| 2003 |
Das P, Howard V, Loosbrock N, Dickson D, Murphy MP, Golde TE. Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8532-8. PMID 13679422 |
0.51 |
|
| 2003 |
Martoglio B, Golde TE. Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs. Human Molecular Genetics. 12: R201-6. PMID 12966028 DOI: 10.1093/hmg/ddg303 |
0.334 |
|
| 2003 |
Eriksen JL, Sagi SA, Smith TE, Weggen S, Das P, McLendon DC, Ozols VV, Jessing KW, Zavitz KH, Koo EH, Golde TE. NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo. The Journal of Clinical Investigation. 112: 440-9. PMID 12897211 DOI: 10.1172/Jci18162 |
0.711 |
|
| 2003 |
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 39: 409-21. PMID 12895417 DOI: 10.1016/S0896-6273(03)00434-3 |
0.535 |
|
| 2003 |
Weggen S, Eriksen JL, Sagi SA, Pietrzik CU, Ozols V, Fauq A, Golde TE, Koo EH. Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity. The Journal of Biological Chemistry. 278: 31831-7. PMID 12805356 DOI: 10.1074/Jbc.M303592200 |
0.648 |
|
| 2003 |
Sagi SA, Weggen S, Eriksen J, Golde TE, Koo EH. The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of kappa B kinase, and NF kappa B, do not reduce amyloid beta 42 production. The Journal of Biological Chemistry. 278: 31825-30. PMID 12805355 DOI: 10.1074/Jbc.M303588200 |
0.657 |
|
| 2003 |
Weggen S, Eriksen JL, Sagi SA, Pietrzik CU, Golde TE, Koo EH. Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain. The Journal of Biological Chemistry. 278: 30748-54. PMID 12777371 DOI: 10.1074/Jbc.M304824200 |
0.689 |
|
| 2003 |
Piper SC, Amtul Z, Galiñanes-Garcia L, Howard VG, Ziani-Cherif C, McLendon C, Rochette MJ, Fauq A, Golde TE, Murphy MP. Peptide-based, irreversible inhibitors of gamma-secretase activity. Biochemical and Biophysical Research Communications. 305: 529-33. PMID 12763025 DOI: 10.1016/S0006-291X(03)00828-3 |
0.406 |
|
| 2003 |
Murphy MP, Das P, Nyborg AC, Rochette MJ, Dodson MW, Loosbrock NM, Souder TM, McLendon C, Merit SL, Piper SC, Jansen KR, Golde TE. Overexpression of nicastrin increases Abeta production. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1138-40. PMID 12692078 DOI: 10.1096/fj.02-1050fje |
0.476 |
|
| 2003 |
Golde TE. Alzheimer disease therapy: can the amyloid cascade be halted? The Journal of Clinical Investigation. 111: 11-8. PMID 12511580 DOI: 10.1172/JCI17527 |
0.339 |
|
| 2003 |
Das P, Howard V, Loosbrock N, Dickson D, Murphy MP, Golde TE. Amyloid-β Immunization Effectively Reduces Amyloid Deposition in FcRγ-/-Knock-Out Mice The Journal of Neuroscience. 23: 8532-8538. DOI: 10.1523/Jneurosci.23-24-08532.2003 |
0.493 |
|
| 2002 |
Tang-Wai D, Lewis P, Boeve B, Hutton M, Golde T, Baker M, Hardy J, Michels V, Ivnik R, Jack C, Petersen R. Familial frontotemporal dementia associated with a novel presenilin-1 mutation. Dementia and Geriatric Cognitive Disorders. 14: 13-21. PMID 12053127 DOI: 10.1159/000058328 |
0.335 |
|
| 2002 |
Sugarman MC, Yamasaki TR, Oddo S, Echegoyen JC, Murphy MP, Golde TE, Jannatipour M, Leissring MA, LaFerla FM. Inclusion body myositis-like phenotype induced by transgenic overexpression of beta APP in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 99: 6334-9. PMID 11972038 DOI: 10.1073/Pnas.082545599 |
0.44 |
|
| 2002 |
Murphy MP, Uljon SN, Golde TE, Wang R. FAD-linked mutations in presenilin 1 alter the length of Abeta peptides derived from betaAPP transmembrane domain mutants. Biochimica Et Biophysica Acta. 1586: 199-209. PMID 11959461 DOI: 10.1016/S0925-4439(01)00098-9 |
0.473 |
|
| 2002 |
Leissring MA, Murphy MP, Mead TR, Akbari Y, Sugarman MC, Jannatipour M, Anliker B, Müller U, Saftig P, De Strooper B, Wolfe MS, Golde TE, LaFerla FM. A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. Proceedings of the National Academy of Sciences of the United States of America. 99: 4697-702. PMID 11917117 DOI: 10.1073/Pnas.072033799 |
0.378 |
|
| 2002 |
Amtul Z, Lewis PA, Piper S, Crook R, Baker M, Findlay K, Singleton A, Hogg M, Younkin L, Younkin SG, Hardy J, Hutton M, Boeve BF, Tang-Wai D, Golde TE. A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch. Neurobiology of Disease. 9: 269-73. PMID 11895378 DOI: 10.1006/Nbdi.2001.0473 |
0.538 |
|
| 2002 |
Wahrle S, Das P, Nyborg AC, McLendon C, Shoji M, Kawarabayashi T, Younkin LH, Younkin SG, Golde TE. Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains. Neurobiology of Disease. 9: 11-23. PMID 11848681 DOI: 10.1006/Nbdi.2001.0470 |
0.511 |
|
| 2002 |
Golde TE, Eriksen JL, Weggen S, Sagi SA, Koo EH. Nonsteroidal antiinflammatory drugs as therapeutic agents for Alzheimer's disease Drug Development Research. 56: 415-420. DOI: 10.1002/Ddr.10093 |
0.706 |
|
| 2001 |
McPhie DL, Golde T, Eckman CB, Yager D, Brant JB, Neve RL. beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations. Brain Research. Molecular Brain Research. 97: 103-13. PMID 11744168 DOI: 10.1016/S0169-328X(01)00294-7 |
0.407 |
|
| 2001 |
Das P, Murphy MP, Younkin LH, Younkin SG, Golde TE. Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition. Neurobiology of Aging. 22: 721-7. PMID 11705631 DOI: 10.1016/S0197-4580(01)00245-7 |
0.642 |
|
| 2001 |
Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature. 414: 212-6. PMID 11700559 DOI: 10.1038/35102591 |
0.749 |
|
| 2001 |
Ni CY, Murphy MP, Golde TE, Carpenter G. gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science (New York, N.Y.). 294: 2179-81. PMID 11679632 DOI: 10.1126/Science.1065412 |
0.315 |
|
| 2001 |
Golde TE, Eckman CB. Cholesterol modulation as an emerging strategy for the treatment of Alzheimer's disease. Drug Discovery Today. 6: 1049-1055. PMID 11590033 DOI: 10.1016/S1359-6446(01)01965-1 |
0.405 |
|
| 2001 |
Palacino JJ, Murphy MP, Murayama O, Iwasaki K, Fujiwara M, Takashima A, Golde TE, Wolozin B. Presenilin 1 regulates beta-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion. The Journal of Biological Chemistry. 276: 38563-9. PMID 11504726 DOI: 10.1074/Jbc.M105376200 |
0.354 |
|
| 2001 |
Haugabook SJ, Yager DM, Eckman EA, Golde TE, Younkin SG, Eckman CB. High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid beta peptide (Abeta). Journal of Neuroscience Methods. 108: 171-9. PMID 11478976 DOI: 10.1016/S0165-0270(01)00388-0 |
0.588 |
|
| 2001 |
Lewis PA, Piper S, Baker M, Onstead L, Murphy MP, Hardy J, Wang R, McGowan E, Golde TE. Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides. Biochimica Et Biophysica Acta. 1537: 58-62. PMID 11476963 DOI: 10.1016/S0925-4439(01)00054-0 |
0.653 |
|
| 2001 |
Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, Sheppard P, Makoff A, Gower E, Soden PE, Lewis P, ... ... Golde TE, et al. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4987-95. PMID 11438574 DOI: 10.1523/Jneurosci.21-14-04987.2001 |
0.417 |
|
| 2001 |
Golde TE, Younkin SG. Presenilins as therapeutic targets for the treatment of Alzheimer's disease. Trends in Molecular Medicine. 7: 264-9. PMID 11378516 DOI: 10.1016/S1471-4914(01)02064-0 |
0.619 |
|
| 2001 |
Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, et al. Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 16-18. PMID 11099491 DOI: 10.1096/Fj.00-0528Fje |
0.623 |
|
| 2001 |
Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K. A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor. The Journal of Biological Chemistry. 276: 481-7. PMID 11035007 DOI: 10.1074/Jbc.M005968200 |
0.366 |
|
| 2000 |
Murphy MP, Wang R, Fraser PE, Fauq A, Golde TE. An empirical model of gamma-secretase activity. Annals of the New York Academy of Sciences. 920: 233-40. PMID 11193156 DOI: 10.1111/J.1749-6632.2000.Tb06928.X |
0.451 |
|
| 2000 |
Houlden H, Baker M, McGowan E, Lewis P, Hutton M, Crook R, Wood NW, Kumar-Singh S, Geddes J, Swash M, Scaravilli F, Holton JL, Lashley T, Tomita T, Hashimoto T, ... ... Golde T, et al. Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. Annals of Neurology. 48: 806-8. PMID 11079548 DOI: 10.1002/1531-8249(200011)48:5<806::Aid-Ana18>3.0.Co;2-F |
0.636 |
|
| 2000 |
McLendon C, Xin T, Ziani-Cherif C, Murphy MP, Findlay KA, Lewis PA, Pinnix I, Sambamurti K, Wang R, Fauq A, Golde TE. Cell-free assays for gamma-secretase activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 2383-6. PMID 11024004 DOI: 10.1096/Fj.00-0286Fje |
0.502 |
|
| 2000 |
Golde TE, Eckman CB, Younkin SG. Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease. Biochimica Et Biophysica Acta. 1502: 172-87. PMID 10899442 DOI: 10.1016/S0925-4439(00)00043-0 |
0.624 |
|
| 2000 |
Murphy MP, Uljon SN, Fraser PE, Fauq A, Lookingbill HA, Findlay KA, Smith TE, Lewis PA, McLendon DC, Wang R, Golde TE. Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage. The Journal of Biological Chemistry. 275: 26277-84. PMID 10816583 DOI: 10.1074/Jbc.M002812200 |
0.472 |
|
| 2000 |
Golde TE, Findlay KA, Smith TE, Thompson S, McLendon DC, Wang R, Murphy MP. Presenilns regulators of γ-secretase cleavage Neurobiology of Aging. 21: 67. DOI: 10.1016/S0197-4580(00)82523-3 |
0.323 |
|
| 2000 |
Lewis PA, McGowan E, Hardy JA, Golde TE. Specific production of Aß peptides from BRI-Aß fusion proteins Neurobiology of Aging. 21: 199. DOI: 10.1016/S0197-4580(00)82238-1 |
0.465 |
|
| 2000 |
Das P, Murphy MP, Younkin LH, Younkin SG, Golde TE. Aβ42 deposition is selectively altered in brains of Aβ1–42 immunized TG2576 mice Neurobiology of Aging. 21: 152-153. DOI: 10.1016/S0197-4580(00)82023-0 |
0.587 |
|
| 1999 |
Murphy MP, Hickman LJ, Eckman CB, Uljon SN, Wang R, Golde TE. gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length. The Journal of Biological Chemistry. 274: 11914-23. PMID 10207012 DOI: 10.1074/Jbc.274.17.11914 |
0.493 |
|
| 1994 |
Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos L, Eckman C, Golde TE, Younkin SG. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science (New York, N.Y.). 264: 1336-40. PMID 8191290 DOI: 10.1126/Science.8191290 |
0.486 |
|
| 1994 |
Nakamura T, Shoji M, Harigaya Y, Watanabe M, Hosoda K, Cheung TT, Shaffer LM, Golde TE, Younkin LH, Younkin SG. Amyloid beta protein levels in cerebrospinal fluid are elevated in early-onset Alzheimer's disease. Annals of Neurology. 36: 903-11. PMID 7998778 DOI: 10.1002/Ana.410360616 |
0.541 |
|
| 1994 |
Cheung TT, Ghiso J, Shojif M, Cai X, Golde T, Gandy S, Frangione B, Younkin S. Characterization by radiosequencing of the carboxyl-terminal derivatives produced from normal and mutant amyloid β protein precursors Amyloid. 1: 30-38. DOI: 10.3109/13506129409148622 |
0.577 |
|
| 1993 |
Cai XD, Golde TE, Younkin SG. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science (New York, N.Y.). 259: 514-6. PMID 8424174 DOI: 10.1126/Science.8424174 |
0.505 |
|
| 1993 |
Wertkin AM, Turner RS, Pleasure SJ, Golde TE, Younkin SG, Trojanowski JQ, Lee VM. Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides. Proceedings of the National Academy of Sciences of the United States of America. 90: 9513-7. PMID 8415732 DOI: 10.1073/Pnas.90.20.9513 |
0.55 |
|
| 1993 |
Kalaria RN, Golde T, Kroon SN, Perry G. Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease. The American Journal of Pathology. 143: 886-93. PMID 8362984 |
0.368 |
|
| 1993 |
Golde TE, Cai XD, Shoji M, Younkin SG. Production of amyloid beta protein from normal amyloid beta-protein precursor (beta APP) and the mutated beta APPS linked to familial Alzheimer's disease. Annals of the New York Academy of Sciences. 695: 103-8. PMID 8239266 DOI: 10.1111/J.1749-6632.1993.Tb23036.X |
0.499 |
|
| 1992 |
Golde TE, Estus S, Younkin LH, Selkoe DJ, Younkin SG. Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science (New York, N.Y.). 255: 728-30. PMID 1738847 DOI: 10.1126/Science.1738847 |
0.485 |
|
| 1992 |
Estus S, Golde TE, Kunishita T, Blades D, Lowery D, Eisen M, Usiak M, Qu XM, Tabira T, Greenberg BD. Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor. Science (New York, N.Y.). 255: 726-8. PMID 1738846 DOI: 10.1126/Science.1738846 |
0.308 |
|
| 1992 |
Gillespie SL, Golde TE, Younkin SG. Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylation. Biochemical and Biophysical Research Communications. 187: 1285-90. PMID 1417805 DOI: 10.1016/0006-291X(92)90442-N |
0.511 |
|
| 1992 |
Estus S, Golde TE, Younkin SG. Normal processing of the Alzheimer's disease amyloid beta protein precursor generates potentially amyloidogenic carboxyl-terminal derivatives. Annals of the New York Academy of Sciences. 674: 138-48. PMID 1288359 DOI: 10.1111/J.1749-6632.1992.Tb27483.X |
0.566 |
|
| 1991 |
Kalaria RN, Golde TE, Cohen ML, Younkin SG. Serum amyloid P in Alzheimer's disease. Implications for dysfunction of the blood-brain barrier. Annals of the New York Academy of Sciences. 640: 145-8. PMID 1776732 DOI: 10.1111/J.1749-6632.1991.Tb00206.X |
0.634 |
|
| 1990 |
Golde TE, Estus S, Usiak M, Younkin LH, Younkin SG. Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. Neuron. 4: 253-67. PMID 2106330 DOI: 10.1016/0896-6273(90)90100-T |
0.508 |
|
| 1990 |
Palmert MR, Podlisny MB, Golde TE, Cohen ML, Kovacs DM, Tanzi RE, Gusella JF, Whitehouse PJ, Witker DS, Oltersdorf T. Analysis of the beta-amyloid protein precursor of Alzheimer's disease: mRNAs and protein products. Advances in Neurology. 51: 181-4. PMID 2104687 |
0.625 |
|
| 1989 |
Palmert MR, Podlisny MB, Golde TE, Cohen ML, Kovacs DM, Tanzi RE, Gusella JF, Whitehouse PJ, Witker DS, Oltersdorf T. The beta amyloid protein precursor: mRNAs, membrane-associated forms, and soluble derivatives. Progress in Clinical and Biological Research. 317: 971-84. PMID 2513588 |
0.62 |
|
| 1989 |
Golde TE, Younkin SG. CONSTRUCTION OF RETROVIRAL VECTORS DESIGNED TO INCREASE EXPRESSION OF THE β AMYLOID PROTEIN AND ITS PRECURSOR Journal of Neuropathology and Experimental Neurology. 48: 341. DOI: 10.1097/00005072-198905000-00128 |
0.477 |
|
| 1988 |
Cohen ML, Golde TE, Usiak MF, Younkin LH, Younkin SG. In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 85: 1227-31. PMID 3277188 DOI: 10.1073/Pnas.85.4.1227 |
0.659 |
|
| 1988 |
Palmert MR, Golde TE, Cohen ML, Kovacs DM, Tanzi RE, Gusella JF, Usiak MF, Younkin LH, Younkin SG. Amyloid protein precursor messenger RNAs: differential expression in Alzheimer's disease. Science (New York, N.Y.). 241: 1080-4. PMID 2457949 |
0.743 |
|
| 1988 |
PALMERT MR, GOLDE TE, COHEN ML, KOVACS DM, TANZI RE, GUSELLA JF, USIAK MF, YOUNKIN LH, YOUNKIN SG. AMYLOID PROTEIN PRECURSOR mRNA LACKING THE KUNITZ PROTEASE INHIBITOR SEQUENCE INCREASES IN AD NUCLEUS BASALIS AND LOCUS CERULEUS NEURONS Alzheimer Disease & Associated Disorders. 2: 401. DOI: 10.1097/00002093-198802040-00031 |
0.726 |
|
| 1987 |
Cohen M, Golde T, Usiak M, Younkin S. IN SITU HYBRIDIZATION IN HUMAN NUCLEUS BASALIS OF MEYNERT Journal of Neuropathology and Experimental Neurology. 46: 365. DOI: 10.1097/00005072-198705000-00106 |
0.493 |
|
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