Anant K. Menon - Publications

Affiliations: 
1989-1993 Molecular Parasitology Rockefeller University, New York, NY, United States 
 1993-2005 Biochemistry University of Wisconsin, Madison, Madison, WI 
 2005- Biochemistry Weill Cornell Medical College, New York, NY, United States 
Area:
Biochemistry

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Menon I, Sych T, Son Y, Morizumi T, Lee J, Ernst OP, Khelashvili G, Sezgin E, Levitz J, Menon AK. A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors. The Journal of Biological Chemistry. 105649. PMID 38237683 DOI: 10.1016/j.jbc.2024.105649  0.353
2023 Jahn H, Bartoš L, Dearden GI, Dittman JS, Holthuis JCM, Vácha R, Menon AK. Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase. Nature Communications. 14: 8115. PMID 38065946 DOI: 10.1038/s41467-023-43570-y  0.432
2023 Menon I, Sych T, Son Y, Morizumi T, Lee J, Ernst OP, Khelashvili G, Sezgin E, Levitz J, Menon AK. A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors. Biorxiv : the Preprint Server For Biology. PMID 38045315 DOI: 10.1101/2023.11.24.568580  0.353
2023 Bartoš L, Menon AK, Vácha R. Insertases Scramble Lipids: Molecular Simulations of MTCH2. Biorxiv : the Preprint Server For Biology. PMID 37645813 DOI: 10.1101/2023.08.14.553169  0.423
2022 Holthuis JCM, Jahn H, Menon AK, Mizushima N. An alliance between lipid transfer proteins and scramblases for membrane expansion. Faculty Reviews. 11: 22. PMID 36081427 DOI: 10.12703/r-01-0000015  0.355
2022 Veit S, Paweletz LC, Bohr SS, Menon AK, Hatzakis NS, Pomorski TG. Single Vesicle Fluorescence-Bleaching Assay for Multi-Parameter Analysis of Proteoliposomes by Total Internal Reflection Fluorescence Microscopy. Acs Applied Materials & Interfaces. 14: 29659-29667. PMID 35748880 DOI: 10.1021/acsami.2c07454  0.403
2022 Morra G, Razavi AM, Menon AK, Khelashvili G. Cholesterol occupies the lipid translocation pathway to block phospholipid scrambling by a G protein-coupled receptor. Structure (London, England : 1993). PMID 35660161 DOI: 10.1016/j.str.2022.05.010  0.382
2022 Wang Y, Menon AK, Maki Y, Liu YS, Iwasaki Y, Fujita M, Guerrero PA, Silva DV, Seeberger PH, Murakami Y, Kinoshita T. Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2115083119. PMID 35344438 DOI: 10.1073/pnas.2115083119  0.455
2021 Khelashvili G, Menon AK. Phospholipid Scrambling by G Protein-Coupled Receptors. Annual Review of Biophysics. PMID 34932914 DOI: 10.1146/annurev-biophys-090821-083030  0.364
2021 Jenni A, Knüsel S, Nagar R, Benninger M, Häner R, Ferguson MAJ, Roditi I, Menon AK, Bütikofer P. Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei. The Journal of Biological Chemistry. 100977. PMID 34284059 DOI: 10.1016/j.jbc.2021.100977  0.323
2021 Mathiassen PPM, Menon AK, Pomorski TG. Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter. Scientific Reports. 11: 14364. PMID 34257324 DOI: 10.1038/s41598-021-93664-0  0.445
2021 Khelashvili G, Pillai AN, Lee J, Pandey K, Payne AM, Siegel Z, Cuendet MA, Lewis TR, Arshavsky VY, Broichhagen J, Levitz J, Menon AK. Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin. Scientific Reports. 11: 10536. PMID 34006992 DOI: 10.1038/s41598-021-90039-3  0.363
2021 Verchère A, Cowton A, Jenni A, Rauch M, Häner R, Graumann J, Bütikofer P, Menon AK. Complexity of the eukaryotic dolichol-linked oligosaccharide scramblase suggested by activity correlation profiling mass spectrometry. Scientific Reports. 11: 1411. PMID 33446867 DOI: 10.1038/s41598-020-80956-0  0.409
2020 Picca G, Probst M, Langenegger SM, Khorev O, Bütikofer P, Menon AK, Häner R. Nonenzymatic synthesis of anomerically pure, mannosyl-based molecular probes for scramblase identification studies. Beilstein Journal of Organic Chemistry. 16: 1732-1739. PMID 32765793 DOI: 10.3762/Bjoc.16.145  0.42
2019 Khelashvili G, Chauhan N, Pandey K, Eliezer D, Menon AK. Exchange of water for sterol underlies sterol egress from a StARkin domain. Elife. 8. PMID 31799930 DOI: 10.7554/Elife.53444  0.379
2019 Chauhan N, Sere YY, Sokol AM, Graumann J, Menon AK. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol binding proteins in Saccharomyces cerevisiae. Yeast (Chichester, England). PMID 31758572 DOI: 10.1002/Yea.3448  0.527
2019 Chandra G, Defour A, Mamchoui K, Pandey K, Mishra S, Mouly V, Sreetama S, Mahad Ahmad M, Mahjneh I, Morizono H, Pattabiraman N, Menon AK, Jaiswal JK. Dysregulated calcium homeostasis prevents plasma membrane repair in Anoctamin 5/TMEM16E-deficient patient muscle cells. Cell Death Discovery. 5: 118. PMID 31341644 DOI: 10.1038/S41420-019-0197-Z  0.349
2019 Chauhan N, Jentsch JA, Menon AK. Measurement of Intracellular Sterol Transport in Yeast. Methods in Molecular Biology (Clifton, N.J.). 1949: 115-136. PMID 30790253 DOI: 10.1007/978-1-4939-9136-5_10  0.453
2018 Wang L, Iwasaki Y, Andra KK, Pandey K, Menon AK, Bütikofer P. Scrambling of natural and fluorescently tagged phosphatidylinositol by reconstituted G protein-coupled receptor and TMEM16 scramblases. The Journal of Biological Chemistry. PMID 30287690 DOI: 10.1074/Jbc.Ra118.004213  0.484
2018 Lee BC, Khelashvili G, Falzone M, Menon AK, Weinstein H, Accardi A. Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase. Nature Communications. 9: 3251. PMID 30108217 DOI: 10.1038/S41467-018-05724-1  0.468
2018 Roelants FM, Chauhan N, Muir A, Davis JC, Menon AK, Levine TP, Thorner J. TOR Complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites. Molecular Biology of the Cell. mbcE18040229. PMID 29927351 DOI: 10.1091/Mbc.E18-04-0229  0.499
2018 Malvezzi M, Andra KK, Pandey K, Lee BC, Falzone ME, Brown A, Iqbal R, Menon AK, Accardi A. Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases. Proceedings of the National Academy of Sciences of the United States of America. PMID 29925604 DOI: 10.1073/Pnas.1806721115  0.517
2018 Andra KK, Dorsey S, Royer C, Menon AK. Structural mapping of fluorescently-tagged, functional nhTMEM16 scramblase in a lipid bilayer. The Journal of Biological Chemistry. PMID 29903908 DOI: 10.1074/Jbc.Ra118.003648  0.479
2018 Menon AK. Sterol gradients in cells. Current Opinion in Cell Biology. 53: 37-43. PMID 29783105 DOI: 10.1016/J.Ceb.2018.04.012  0.486
2018 Quon E, Sere YY, Chauhan N, Johansen J, Sullivan DP, Dittman JS, Rice WJ, Chan RB, di Paolo G, Beh CT, Menon AK. Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation. Plos Biology. 16: e2003864. PMID 29782498 DOI: 10.1371/Journal.Pbio.2003864  0.699
2018 Kobayashi T, Menon AK. Transbilayer lipid asymmetry. Current Biology : Cb. 28: R386-R391. PMID 29689220 DOI: 10.1016/J.Cub.2018.01.007  0.496
2018 Jentsch JA, Kiburu I, Pandey K, Timme M, Ramlall T, Levkau B, Wu J, Eliezer D, Boudker O, Menon AK. Structural basis of sterol binding and transport by a yeast StARkin domain. The Journal of Biological Chemistry. PMID 29463678 DOI: 10.1074/Jbc.Ra118.001881  0.542
2017 Morra G, Razavi AM, Pandey K, Weinstein H, Menon AK, Khelashvili G. Mechanisms of Lipid Scrambling by the G Protein-Coupled Receptor Opsin. Structure (London, England : 1993). PMID 29290486 DOI: 10.1016/J.Str.2017.11.020  0.432
2017 Solanko LM, Sullivan DP, Sere YY, Szomek M, Lunding A, Solanko KA, Pizovic A, Stanchev LD, Pomorski TG, Menon AK, Wüstner D. Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane. Traffic (Copenhagen, Denmark). PMID 29282820 DOI: 10.1111/Tra.12545  0.65
2017 Pandey K, Ploier B, Goren MA, Levitz J, Khelashvili G, Menon AK. An engineered opsin monomer scrambles phospholipids. Scientific Reports. 7: 16741. PMID 29196630 DOI: 10.1038/S41598-017-16842-Z  0.468
2017 Verchère A, Ou WL, Ploier B, Morizumi T, Goren MA, Bütikofer P, Ernst OP, Khelashvili G, Menon AK. Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum. Scientific Reports. 7: 9522. PMID 28842688 DOI: 10.1038/S41598-017-09835-5  0.527
2017 Yi L, Bozkurt G, Li Q, Lo S, Menon AK, Wu H. Disulfide Bond Formation and N-Glycosylation Modulate Protein-Protein Interactions in GPI-Transamidase (GPIT). Scientific Reports. 8: 45912. PMID 28374821 DOI: 10.1038/Srep45912  0.354
2017 Cotton RJ, Ploier B, Goren MA, Menon AK, Graumann J. flippant-An R package for the automated analysis of fluorescence-based scramblase assays. Bmc Bioinformatics. 18: 146. PMID 28253836 DOI: 10.1186/S12859-017-1542-Y  0.412
2017 Khelashvili G, Cheol Lee B, Falzone M, Menon AK, Accardi A, Weinstein H. Role of Hydrophilic Groove of the TMEM16 Protein in Lipid Scrambling Biophysical Journal. 112: 392a. DOI: 10.1016/J.Bpj.2016.11.2131  0.477
2017 Pandey K, Ploier B, Goren M, Khelashvili G, Menon A. An Opsin Monomer Scrambles Phospholipids Biophysical Journal. 112: 391a. DOI: 10.1016/J.Bpj.2016.11.2126  0.443
2017 Khelashvili G, Pandey K, Weinstein H, Menon AK. Molecular Mechanism of Lipid Scrambling by Opsin Biophysical Journal. 112: 391a. DOI: 10.1016/J.Bpj.2016.11.2125  0.543
2017 Lee B, Falzone M, Menon A, Accardi A. Identification of Residues Important for Ion and Lipid Transport in a TMEM16 Scramblase Biophysical Journal. 112: 228a. DOI: 10.1016/J.Bpj.2016.11.1254  0.391
2016 Dittman JS, Menon AK. Speed Limits for Nonvesicular Intracellular Sterol Transport. Trends in Biochemical Sciences. PMID 27956059 DOI: 10.1016/J.Tibs.2016.11.004  0.506
2016 Gottier P, Gonzalez-Salgado A, Menon AK, Liu YC, Acosta-Serrano A, Bütikofer P. RFT1 affects GPI anchor glycosylation. The Journal of Biological Chemistry. PMID 27927990 DOI: 10.1074/Jbc.M116.758367  0.535
2016 Lee BC, Menon AK, Accardi A. The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel. Biophysical Journal. 111: 1919-1924. PMID 27806273 DOI: 10.1016/J.Bpj.2016.09.032  0.412
2016 Ploier B, Caro LN, Morizumi T, Pandey K, Pearring JN, Goren MA, Finnemann SC, Graumann J, Arshavsky VY, Dittman JS, Ernst OP, Menon AK. Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants. Nature Communications. 7: 12832. PMID 27694816 DOI: 10.1038/Ncomms12832  0.344
2016 Ploier B, Menon AK. A Fluorescence-based Assay of Phospholipid Scramblase Activity. Journal of Visualized Experiments : Jove. PMID 27684510 DOI: 10.3791/54635  0.488
2016 Pomorski TG, Menon AK. Lipid somersaults: Uncovering the mechanisms of protein-mediated lipid flipping. Progress in Lipid Research. PMID 27528189 DOI: 10.1016/J.Plipres.2016.08.003  0.498
2016 Menon AK, Levine T. The cellular lipid landscape. Biochimica Et Biophysica Acta. PMID 27179417 DOI: 10.1016/J.Bbalip.2016.05.004  0.364
2016 Chauhan N, Farine L, Pandey K, Menon AK, Bütikofer P. Lipid topogenesis - 35years on. Biochimica Et Biophysica Acta. PMID 26946259 DOI: 10.1016/J.Bbalip.2016.02.025  0.497
2016 Malvezzi M, Iqbal R, Brown A, Menon A, Accardi A. Sizing up the Lipid Pathway in a TMEM16 Phospholipid Scramblase Biophysical Journal. 110: 291a. DOI: 10.1016/J.Bpj.2015.11.1573  0.422
2015 Hankins HM, Sere YY, Diab NS, Menon AK, Graham TR. Phosphatidylserine translocation at the yeast trans-Golgi network regulates protein sorting into exocytic vesicles. Molecular Biology of the Cell. PMID 26466678 DOI: 10.1091/Mbc.E15-07-0487  0.54
2015 Menon AK, Levine TP. Cell biology: Countercurrents in lipid flow. Nature. 525: 191-2. PMID 26354476 DOI: 10.1038/525191A  0.473
2015 Verchère A, Menon AK. Structural biology: Lipid gymnastics. Nature. 524: 420-2. PMID 26266983 DOI: 10.1038/Nature15202  0.455
2015 Ernst OP, Menon AK. Phospholipid scrambling by rhodopsin. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 26179029 DOI: 10.1039/C5Pp00195A  0.402
2015 Gatta AT, Wong LH, Sere YY, Calderón-Noreña DM, Cockcroft S, Menon AK, Levine TP. A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport. Elife. 4. PMID 26001273 DOI: 10.7554/Elife.07253  0.486
2015 Gatta AT, Wong LH, Sere YY, Calderón-Noreña DM, Cockcroft S, Menon AK, Levine TP. Author response: A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport Elife. DOI: 10.7554/Elife.07253.024  0.463
2014 Goren MA, Morizumi T, Menon I, Joseph JS, Dittman JS, Cherezov V, Stevens RC, Ernst OP, Menon AK. Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Nature Communications. 5: 5115. PMID 25296113 DOI: 10.1038/Ncomms6115  0.512
2014 Holthuis JC, Menon AK. Lipid landscapes and pipelines in membrane homeostasis. Nature. 510: 48-57. PMID 24899304 DOI: 10.1038/Nature13474  0.423
2014 Malvezzi M, Janjusevic R, Menon A, Accardi A. Lipid Modulation of a Dual Function TMEM16 Channel/Scramblase Biophysical Journal. 106: 155a. DOI: 10.1016/J.Bpj.2013.11.890  0.399
2013 Levine TP, Menon AK. A protein pair with PIPs inside. Structure (London, England : 1993). 21: 1070-1. PMID 23823324 DOI: 10.1016/J.Str.2013.06.010  0.416
2013 Jelk J, Gao N, Serricchio M, Signorell A, Schmidt RS, Bangs JD, Acosta-Serrano A, Lehrman MA, Bütikofer P, Menon AK. Glycoprotein biosynthesis in a eukaryote lacking the membrane protein Rft1. The Journal of Biological Chemistry. 288: 20616-23. PMID 23720757 DOI: 10.1074/Jbc.M113.479642  0.422
2013 Georgiev AG, Johansen J, Ramanathan VD, Sere YY, Beh CT, Menon AK. Arv1 regulates PM and ER membrane structure and homeostasis but is dispensable for intracellular sterol transport. Traffic (Copenhagen, Denmark). 14: 912-21. PMID 23668914 DOI: 10.1111/Tra.12082  0.579
2013 Malvezzi M, Chalat M, Terashima H, Janjusevic R, Menon A, Accardi A. Ca2+-Dependent Ion and Lipid Transport Mediated by a Fungal TMEM16 Homologue Biophysical Journal. 104: 366a. DOI: 10.1016/J.Bpj.2012.11.2034  0.349
2013 Goren MA, Ernst O, Menon AK. The Photoreceptor Rhodopsin is a Constitutively Active Lipid Flippase Biophysical Journal. 104: 218a. DOI: 10.1016/J.Bpj.2012.11.1231  0.481
2012 Chalat M, Menon I, Turan Z, Menon AK. Reconstitution of glucosylceramide flip-flop across endoplasmic reticulum: implications for mechanism of glycosphingolipid biosynthesis. The Journal of Biological Chemistry. 287: 15523-32. PMID 22427661 DOI: 10.1074/Jbc.M112.343038  0.572
2012 Beh CT, McMaster CR, Kozminski KG, Menon AK. A detour for yeast oxysterol binding proteins. The Journal of Biological Chemistry. 287: 11481-8. PMID 22334669 DOI: 10.1074/Jbc.R111.338400  0.506
2011 Georgiev AG, Sullivan DP, Kersting MC, Dittman JS, Beh CT, Menon AK. Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM. Traffic (Copenhagen, Denmark). 12: 1341-55. PMID 21689253 DOI: 10.1111/J.1600-0854.2011.01234.X  0.69
2011 Menon I, Huber T, Sanyal S, Banerjee S, Barré P, Canis S, Warren JD, Hwa J, Sakmar TP, Menon AK. Opsin is a phospholipid flippase. Current Biology : Cb. 21: 149-53. PMID 21236677 DOI: 10.1016/J.Cub.2010.12.031  0.781
2011 Menon AK, Herrmann A. Phospholipid Flip-Flop in Biogenic Membranes Transmembrane Dynamics of Lipids. 97-118. DOI: 10.1002/9781118120118.ch6  0.385
2010 Sanyal S, Menon AK. Stereoselective transbilayer translocation of mannosyl phosphoryl dolichol by an endoplasmic reticulum flippase. Proceedings of the National Academy of Sciences of the United States of America. 107: 11289-94. PMID 20534553 DOI: 10.1073/Pnas.1002408107  0.786
2009 Sanyal S, Menon AK. Flipping lipids: why an' what's the reason for? Acs Chemical Biology. 4: 895-909. PMID 19689162 DOI: 10.1021/Cb900163D  0.786
2009 Sanyal S, Menon AK. Specific transbilayer translocation of dolichol-linked oligosaccharides by an endoplasmic reticulum flippase. Proceedings of the National Academy of Sciences of the United States of America. 106: 767-72. PMID 19129492 DOI: 10.1073/Pnas.0810225106  0.763
2009 Beh CT, Alfaro G, Duamel G, Sullivan DP, Kersting MC, Dighe S, Kozminski KG, Menon AK. Yeast oxysterol-binding proteins: sterol transporters or regulators of cell polarization? Molecular and Cellular Biochemistry. 326: 9-13. PMID 19125315 DOI: 10.1007/S11010-008-9999-7  0.686
2009 Sullivan DP, Georgiev A, Menon AK. Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae. Eukaryotic Cell. 8: 161-9. PMID 19060182 DOI: 10.1128/Ec.00135-08  0.644
2009 Menon AK. Chapter 8 Split Topology of GPI Biosynthesis Enzymes. 26: 151-158. DOI: 10.1016/S1874-6047(09)26008-2  0.433
2009 Signorell A, Menon AK. Chapter 7 attachment of a GPI anchor to protein Enzymes. 26: 133-149. DOI: 10.1016/S1874-6047(09)26007-0  0.411
2008 Frank CG, Sanyal S, Rush JS, Waechter CJ, Menon AK. Does Rft1 flip an N-glycan lipid precursor? Nature. 454: E3-4; discussion E4-. PMID 18668045 DOI: 10.1038/Nature07165  0.763
2008 Sanyal S, Frank CG, Menon AK. Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry. 47: 7937-46. PMID 18597486 DOI: 10.1021/Bi800723N  0.765
2008 Menon AK. Lipid modifications of proteins Biochemistry of Lipids, Lipoproteins and Membranes. 39-58. DOI: 10.1016/B978-044453219-0.50004-0  0.314
2008 Baumann NA, Menon AK, Rancour DM. Functions of glycosyl phosphatidylinositols Carbohydrates in Chemistry and Biology. 4: 757-769. DOI: 10.1002/9783527618255.ch85  0.747
2007 Menon AK. A flip-flop switch in polarity signaling. Developmental Cell. 13: 607-8. PMID 17981130 DOI: 10.1016/J.Devcel.2007.10.008  0.375
2007 Shukla S, Rai V, Saini P, Banerjee D, Menon AK, Prasad R. Candida drug resistance protein 1, a major multidrug ATP binding cassette transporter of Candida albicans, translocates fluorescent phospholipids in a reconstituted system. Biochemistry. 46: 12081-90. PMID 17924650 DOI: 10.1021/bi700453e  0.343
2007 Vehring S, Pakkiri L, Schröer A, Alder-Baerens N, Herrmann A, Menon AK, Pomorski T. Flip-flop of fluorescently labeled phospholipids in proteoliposomes reconstituted with Saccharomyces cerevisiae microsomal proteins. Eukaryotic Cell. 6: 1625-34. PMID 17616631 DOI: 10.1128/Ec.00198-07  0.481
2007 Orlean P, Menon AK. Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids. Journal of Lipid Research. 48: 993-1011. PMID 17361015 DOI: 10.1194/Jlr.R700002-Jlr200  0.536
2007 Sutterwala SS, Creswell CH, Sanyal S, Menon AK, Bangs JD. De novo sphingolipid synthesis is essential for viability, but not for transport of glycosylphosphatidylinositol-anchored proteins, in African trypanosomes. Eukaryotic Cell. 6: 454-64. PMID 17220466 DOI: 10.1128/Ec.00283-06  0.748
2006 Pomorski T, Menon AK. Lipid flippases and their biological functions. Cellular and Molecular Life Sciences : Cmls. 63: 2908-21. PMID 17103115 DOI: 10.1007/S00018-006-6167-7  0.559
2006 Vainauskas S, Menon AK. Ethanolamine phosphate linked to the first mannose residue of glycosylphosphatidylinositol (GPI) lipids is a major feature of the GPI structure that is recognized by human GPI transamidase. The Journal of Biological Chemistry. 281: 38358-64. PMID 17060324 DOI: 10.1074/Jbc.M608896200  0.39
2006 Maxfield FR, Menon AK. Intracellular sterol transport and distribution. Current Opinion in Cell Biology. 18: 379-85. PMID 16806879 DOI: 10.1016/J.Ceb.2006.06.012  0.549
2006 Sullivan DP, Ohvo-Rekilä H, Baumann NA, Beh CT, Menon AK. Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast. Biochemical Society Transactions. 34: 356-8. PMID 16709160 DOI: 10.1042/Bst0340356  0.785
2006 Gruszynski AE, van Deursen FJ, Albareda MC, Best A, Chaudhary K, Cliffe LJ, del Rio L, Dunn JD, Ellis L, Evans KJ, Figueiredo JM, Malmquist NA, Omosun Y, Palenchar JB, Prickett S, ... ... Menon AK, et al. Regulation of surface coat exchange by differentiating African trypanosomes. Molecular and Biochemical Parasitology. 147: 211-23. PMID 16564583 DOI: 10.1016/J.Molbiopara.2006.02.013  0.324
2005 Baumann NA, Sullivan DP, Ohvo-Rekilä H, Simonot C, Pottekat A, Klaassen Z, Beh CT, Menon AK. Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration. Biochemistry. 44: 5816-26. PMID 15823040 DOI: 10.1021/Bi048296Z  0.794
2005 Vishwakarma RA, Vehring S, Mehta A, Sinha A, Pomorski T, Herrmann A, Menon AK. New fluorescent probes reveal that flippase-mediated flip-flop of phosphatidylinositol across the endoplasmic reticulum membrane does not depend on the stereochemistry of the lipid. Organic & Biomolecular Chemistry. 3: 1275-83. PMID 15785818 DOI: 10.1039/B500300H  0.562
2005 Vainauskas S, Menon AK. Endoplasmic reticulum localization of Gaa1 and PIG-T, subunits of the glycosylphosphatidylinositol transamidase complex. The Journal of Biological Chemistry. 280: 16402-9. PMID 15713669 DOI: 10.1074/Jbc.M414253200  0.481
2004 Chang QL, Gummadi SN, Menon AK. Chemical modification identifies two populations of glycerophospholipid flippase in rat liver ER. Biochemistry. 43: 10710-8. PMID 15311932 DOI: 10.1021/Bi049063A  0.538
2004 Pottekat A, Menon AK. Subcellular localization and targeting of N-acetylglucosaminyl phosphatidylinositol de-N-acetylase, the second enzyme in the glycosylphosphatidylinositol biosynthetic pathway. The Journal of Biological Chemistry. 279: 15743-51. PMID 14742432 DOI: 10.1074/Jbc.M313537200  0.786
2004 Vainauskas S, Menon AK. A conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol (GPI) recognition by GPI transamidase. The Journal of Biological Chemistry. 279: 6540-5. PMID 14660601 DOI: 10.1074/Jbc.M312191200  0.397
2003 Kostova Z, Yan BC, Vainauskas S, Schwartz R, Menon AK, Orlean P. Comparative importance in vivo of conserved glutamate residues in the EX7E motif retaining glycosyltransferase Gpi3p, the UDP-GlcNAc-binding subunit of the first enzyme in glycosylphosphatidylinositol assembly. European Journal of Biochemistry / Febs. 270: 4507-14. PMID 14622279 DOI: 10.1046/J.1432-1033.2003.03844.X  0.421
2003 Potocky TB, Menon AK, Gellman SH. Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells. The Journal of Biological Chemistry. 278: 50188-94. PMID 14517218 DOI: 10.1074/Jbc.M308719200  0.304
2003 Gummadi SN, Hrafnsdóttir S, Walent J, Watkins WE, Menon AK. Reconstitution and assay of biogenic membrane-derived phospholipid flippase activity in proteoliposomes. Methods in Molecular Biology (Clifton, N.J.). 228: 271-9. PMID 12824560 DOI: 10.1385/1-59259-400-X:271  0.806
2002 Watkins WE, Menon AK. Reconstitution of phospholipid flippase activity from E. coli inner membrane: a test of the protein translocon as a candidate flippase. Biological Chemistry. 383: 1435-40. PMID 12437136 DOI: 10.1515/Bc.2002.162  0.533
2002 Menon AK. Introduction: lipid transport--an overview. Seminars in Cell & Developmental Biology. 13: 159-62. PMID 12137735 DOI: 10.1016/S1084-9521(02)00043-5  0.406
2002 Vainauskas S, Maeda Y, Kurniawan H, Kinoshita T, Menon AK. Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex. The Journal of Biological Chemistry. 277: 30535-42. PMID 12052837 DOI: 10.1074/Jbc.M205402200  0.494
2002 Gummadi SN, Menon AK. Transbilayer movement of dipalmitoylphosphatidylcholine in proteoliposomes reconstituted from detergent extracts of endoplasmic reticulum. Kinetics of transbilayer transport mediated by a single flippase and identification of protein fractions enriched in flippase activity. The Journal of Biological Chemistry. 277: 25337-43. PMID 12000768 DOI: 10.1074/Jbc.M203809200  0.526
2002 Kubelt J, Menon AK, Müller P, Herrmann A. Transbilayer movement of fluorescent phospholipid analogues in the cytoplasmic membrane of Escherichia coli. Biochemistry. 41: 5605-12. PMID 11969421 DOI: 10.1021/Bi0118714  0.415
2002 Baumann NA, Menon AK. Chapter 2 Lipid modifications of proteins New Comprehensive Biochemistry. 36: 37-54. DOI: 10.1016/S0167-7306(02)36004-6  0.725
2001 Li J, Rancour DM, Allende ML, Worth CA, Darling DS, Gilbert JB, Menon AK, Young WW. The DXD motif is required for GM2 synthase activity but is not critical for nucleotide binding. Glycobiology. 11: 217-29. PMID 11320060 DOI: 10.1093/Glycob/11.3.217  0.734
2001 Vidugiriene J, Vainauskas S, Johnson AE, Menon AK. Endoplasmic reticulum proteins involved in glycosylphosphatidylinositol-anchor attachment: photocrosslinking studies in a cell-free system. European Journal of Biochemistry / Febs. 268: 2290-300. PMID 11298746 DOI: 10.1046/J.1432-1327.2001.02106.X  0.477
2000 Sharma DK, Hilley JD, Bangs JD, Coombs GH, Mottram JC, Menon AK. Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins. The Biochemical Journal. 351: 717-22. PMID 11042127 DOI: 10.1042/Bj3510717  0.445
2000 Kostova Z, Rancour DM, Menon AK, Orlean P. Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis. The Biochemical Journal. 350: 815-22. PMID 10970797 DOI: 10.1042/Bj3500815  0.754
2000 Hrafnsdóttir S, Menon AK. Reconstitution and partial characterization of phospholipid flippase activity from detergent extracts of the Bacillus subtilis cell membrane. Journal of Bacteriology. 182: 4198-206. PMID 10894727 DOI: 10.1128/Jb.182.15.4198-4206.2000  0.835
2000 McConville MJ, Menon AK. Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids (review). Molecular Membrane Biology. 17: 1-16. PMID 10824734 DOI: 10.1080/096876800294443  0.414
2000 Menon AK, Watkins WE3rd, Hrafnsdóttir S. Specific proteins are required to translocate phosphatidylcholine bidirectionally across the endoplasmic reticulum. Current Biology : Cb. 10: 241-52. PMID 10712902 DOI: 10.1016/S0960-9822(00)00356-0  0.836
2000 Baumann NA, Vidugiriene J, Machamer CE, Menon AK. Cell surface display and intracellular trafficking of free glycosylphosphatidylinositols in mammalian cells. The Journal of Biological Chemistry. 275: 7378-89. PMID 10702311 DOI: 10.1074/Jbc.275.10.7378  0.733
1999 Sharma DK, Vidugiriene J, Bangs JD, Menon AK. A cell-free assay for glycosylphosphatidylinositol anchoring in African trypanosomes. Demonstration of a transamidation reaction mechanism. The Journal of Biological Chemistry. 274: 16479-86. PMID 10347210 DOI: 10.1074/Jbc.274.23.16479  0.454
1999 Vidugiriene J, Sharma DK, Smith TK, Baumann NA, Menon AK. Segregation of glycosylphosphatidylinositol biosynthetic reactions in a subcompartment of the endoplasmic reticulum. The Journal of Biological Chemistry. 274: 15203-12. PMID 10329729 DOI: 10.1074/Jbc.274.21.15203  0.665
1999 Puglielli L, Mandon EC, Rancour DM, Menon AK, Hirschberg CB. Identification and purification of the rat liver Golgi membrane UDP-N-acetylgalactosamine transporter. The Journal of Biological Chemistry. 274: 4474-9. PMID 9933652 DOI: 10.1074/Jbc.274.7.4474  0.793
1998 Menon AK. Lipids: more than just membrane fabric. Trends in Cell Biology. 8: 374-6. PMID 9728399 DOI: 10.1016/S0962-8924(98)01340-3  0.461
1998 Rancour DM, Menon AK. Identification of endoplasmic reticulum proteins involved in glycan assembly: synthesis and characterization of P3-(4-azidoanilido)uridine 5'-triphosphate, a membrane-topological photoaffinity probe for uridine diphosphate-sugar binding proteins. The Biochemical Journal. 333: 661-9. PMID 9677326 DOI: 10.1042/Bj3330661  0.802
1997 Menon AK, Baumann NA, van't Hof W, Vidugiriene J. Glycosylphosphatidylinositols: biosynthesis and intracellular transport. Biochemical Society Transactions. 25: 861-5. PMID 9388562 DOI: 10.1042/Bst0250861  0.642
1997 Hrafnsdóttir S, Nichols JW, Menon AK. Transbilayer movement of fluorescent phospholipids in Bacillus megaterium membrane vesicles. Biochemistry. 36: 4969-78. PMID 9125519 DOI: 10.1021/bi962513h  0.812
1997 Menon AK. GPI anchors: biosynthesis, intracellular transport, and linkage to protein Biochemical Society Transactions. 25: 419S. DOI: 10.1042/Bst025419Se  0.546
1996 Bütikofer P, Boschung M, Brodbeck U, Menon AK. Phosphatidylinositol hydrolysis by Trypanosoma brucei glycosylphosphatidylinositol phospholipase C. The Journal of Biological Chemistry. 271: 15533-41. PMID 8663180 DOI: 10.1074/Jbc.271.26.15533  0.325
1995 Menon AK. Flippases. Trends in Cell Biology. 5: 355-60. PMID 14732078 DOI: 10.1016/S0962-8924(00)89069-8  0.397
1995 Bütikofer P, Boschung M, Menon AK. Production of a nested set of glycosylphosphatidylinositol structures from a glycosylphosphatidylinositol-anchored protein. Analytical Biochemistry. 229: 125-32. PMID 8533881 DOI: 10.1006/Abio.1995.1388  0.416
1995 van't Hof W, Rodriguez-Boulan E, Menon AK. Nonpolarized distribution of glycosylphosphatidylinositols in the plasma membrane of polarized Madin-Darby canine kidney cells. The Journal of Biological Chemistry. 270: 24150-5. PMID 7592618 DOI: 10.1074/Jbc.270.41.24150  0.535
1995 Vidugiriene J, Menon AK. Soluble constituents of the ER lumen are required for GPI anchoring of a model protein. The Embo Journal. 14: 4686-94. PMID 7588598 DOI: 10.1016/0169-4758(95)80055-7  0.459
1995 Vidugiriene J, Menon AK. Biosynthesis of glycosylphosphatidylinositol anchors. Methods in Enzymology. 250: 513-35. PMID 7544424 DOI: 10.1016/0076-6879(95)50094-4  0.525
1994 Menon AK, Vidugiriene J. Topology of GPI biosynthesis in the endoplasmic reticulum. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 27: 167-75. PMID 8081226  0.395
1994 Vidugiriene J, Menon AK. The GPI anchor of cell-surface proteins is synthesized on the cytoplasmic face of the endoplasmic reticulum. The Journal of Cell Biology. 127: 333-41. PMID 7929579 DOI: 10.1083/Jcb.127.2.333  0.529
1993 Vidugiriene J, Menon AK. Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer. The Journal of Cell Biology. 121: 987-96. PMID 8501124 DOI: 10.1083/Jcb.121.5.987  0.497
1993 Menon AK, Eppinger M, Mayor S, Schwarz RT. Phosphatidylethanolamine is the donor of the terminal phosphoethanolamine group in trypanosome glycosylphosphatidylinositols. The Embo Journal. 12: 1907-14. PMID 8491183 DOI: 10.1002/J.1460-2075.1993.Tb05839.X  0.566
1993 Patnaik PK, Field MC, Menon AK, Cross GA, Yee MC, Bütikofer P. Molecular species analysis of phospholipids from Trypanosoma brucei bloodstream and procyclic forms. Molecular and Biochemical Parasitology. 58: 97-105. PMID 8459838 DOI: 10.1016/0166-6851(93)90094-E  0.526
1992 Menon AK, Stevens VL. Phosphatidylethanolamine is the donor of the ethanolamine residue linking a glycosylphosphatidylinositol anchor to protein. The Journal of Biological Chemistry. 267: 15277-80. PMID 1322394  0.317
1992 Mayor S, Menon AK, Cross GA. Galactose-containing glycosylphosphatidylinositols in Trypanosoma brucei. The Journal of Biological Chemistry. 267: 754-61. PMID 1309774  0.628
1991 Löw P, Dallner G, Mayor S, Cohen S, Chait BT, Menon AK. The mevalonate pathway in the bloodstream form of Trypanosoma brucei. Identification of dolichols containing 11 and 12 isoprene residues. The Journal of Biological Chemistry. 266: 19250-7. PMID 1918042  0.508
1991 Menon AK. Biosynthesis of glycosyl-phosphatidylinositol. Cell Biology International Reports. 15: 1007-21. PMID 1838300 DOI: 10.1016/0309-1651(91)90053-L  0.359
1991 Lisanti MP, Field MC, Caras IW, Menon AK, Rodriguez-Boulan E. Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins. The Embo Journal. 10: 1969-77. PMID 1829673 DOI: 10.1002/J.1460-2075.1991.Tb07726.X  0.5
1991 Mayor S, Menon AK, Cross GA. Transfer of glycosyl-phosphatidylinositol membrane anchors to polypeptide acceptors in a cell-free system. The Journal of Cell Biology. 114: 61-71. PMID 1828808 DOI: 10.1083/Jcb.114.1.61  0.754
1991 Field MC, Menon AK, Cross GA. A glycosylphosphatidylinositol protein anchor from procyclic stage Trypanosoma brucei: lipid structure and biosynthesis. The Embo Journal. 10: 2731-9. PMID 1655402  0.321
1991 FIELD MC, MENON AK. Biosynthesis of Glycolipid Anchors in Trypanosoma brucei. Trends in Glycoscience and Glycotechnology. 3: 107-115. DOI: 10.4052/Tigg.3.107  0.365
1991 Field M, Menon A, Cross G. A glycosylphosphatidylinositol protein anchor from procyclic stage Trypanosoma brucei: lipid structure and biosynthesis. The Embo Journal. 10: 2731-2739. DOI: 10.1002/J.1460-2075.1991.Tb07821.X  0.63
1990 Menon AK, Mayor S, Schwarz RT. Biosynthesis of glycosyl-phosphatidylinositol lipids in Trypanosoma brucei: Involvement of mannosylphosphoryldolichol as the mannose donor Embo Journal. 9: 4249-4258. PMID 2148289 DOI: 10.1002/J.1460-2075.1990.Tb07873.X  0.623
1990 Mayor S, Menon AK, Cross GA. Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins. II. Lipid structures of phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids. The Journal of Biological Chemistry. 265: 6174-81. PMID 2138615  0.658
1990 Mayor S, Menon AK, Cross GA, Ferguson MA, Dwek RA, Rademacher TW. Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins. I. Can structure of the phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids. The Journal of Biological Chemistry. 265: 6164-73. PMID 2138614  0.678
1990 Menon AK, Schwarz RT, Mayor S, Cross GA. Cell-free synthesis of glycosyl-phosphatidylinositol precursors for the glycolipid membrane anchor of Trypanosoma brucei variant surface glycoproteins. Structural characterization of putative biosynthetic intermediates. The Journal of Biological Chemistry. 265: 9033-42. PMID 1693147  0.704
1990 Mayor S, Menon AK. Structural analysis of the glycosylinositol phospholipid anchors of membrane proteins Methods. 1: 297-305. DOI: 10.1016/S1046-2023(05)80331-7  0.647
1989 SCHWARZ RT, MAYOR S, MENON AK, CROSS GAM. Biosynthesis of the glycolipid membrane anchor of Trypanosoma brucei variant surface glycoproteins: involvement of Dol-P-Man Biochemical Society Transactions. 17: 746-748. DOI: 10.1042/Bst0170746  0.609
1989 Schwarz RT, Mayor S, Menon AK, Cross GAM. Biosynthesis of the glycolipid membrane anchor of Trypanosoma brucei variant surface glycoproteins: involvement of Dol-P-Man Biochemical Society Transactions. 17: 746-748.  0.338
1988 Menon AK, Mayor S, Ferguson MA, Duszenko M, Cross GA. Candidate glycophospholipid precursor for the glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoproteins. The Journal of Biological Chemistry. 263: 1970-7. PMID 3339000  0.646
1988 MENON AK, SCHWARZ RT, MAYOR S, CROSS GAM. Glycolipid precursor of Trypanosoma brucei variant surface glycoproteins: incorporation of radiolabelled mannose and myristic acid in a cell-free system Biochemical Society Transactions. 16: 996-997. DOI: 10.1042/Bst0160996  0.504
1986 Menon AK, Holowka D, Webb WW, Baird B. Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization. The Journal of Cell Biology. 102: 541-50. PMID 2935543 DOI: 10.1083/Jcb.102.2.541  0.531
1986 Menon AK, Holowka D, Webb WW, Baird B. Clustering, mobility, and triggering activity of small oligomers of immunoglobulin E on rat basophilic leukemia cells. The Journal of Cell Biology. 102: 534-40. PMID 2418032 DOI: 10.1083/Jcb.102.2.534  0.539
1984 Menon AK, Holowka D, Baird B. Small oligomers of immunoglobulin E (IgE) cause large-scale clustering of IgE receptors on the surface of rat basophilic leukemia cells Journal of Cell Biology. 98: 577-583. PMID 6229545 DOI: 10.1083/Jcb.98.2.577  0.515
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