Robert J. Deschenes - Publications

Affiliations: 
1989-2004 Biochemistry University of Iowa, Iowa City, IA 
 2004-2008 Biochemistry Medical College of Wisconsin, Milwaukee, WI, United States 
 2008- Molecular Medicine University of South Florida, Tampa, FL, United States 
Area:
Biochemistry
Website:
https://health.usf.edu/medicine/nsi/executive-committee/63715/Deschenes

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ramadan A, Conniff AS, Kirouac L, Deschenes R. Identification of regulatory elements in the C‐terminus of the Protein Acyl Transferase, zDHHC9. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09481  0.358
2019 Mitchell DA, Pendleton LC, Deschenes RJ. In Vitro Assays to Monitor the Enzymatic Activities of zDHHC Protein Acyltransferases. Methods in Molecular Biology (Clifton, N.J.). 2009: 169-177. PMID 31152403 DOI: 10.1007/978-1-4939-9532-5_13  0.359
2016 Reddy KD, Malipeddi J, DeForte S, Pejaver V, Radivojac P, Uversky VN, Deschenes RJ. Physicochemical sequence characteristics that influence S-palmitoylation propensity. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 27498722 DOI: 10.1080/07391102.2016.1217275  0.43
2016 Hamel LD, Lenhart BJ, Mitchell DA, Santos RG, Giulianotti MA, Deschenes RJ. Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library. Combinatorial Chemistry & High Throughput Screening. PMID 27009891 DOI: 10.2174/1386207319666160324123844  0.362
2015 Reddy KD, Baker JD, Xue B, Deschenes RJ, Uversky VN. The Intrinsically Disordered Termini of zDHHC S-Palmitoyltransferases Facilitate Multiple Regulatory Functions Biophysical Journal. 108: 387a. DOI: 10.1016/J.Bpj.2014.11.2123  0.452
2014 Hamel LD, Deschenes RJ, Mitchell DA. A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening. Analytical Biochemistry. 460: 1-8. PMID 24878334 DOI: 10.1016/J.Ab.2014.05.013  0.575
2014 Mitchell DA, Hamel LD, Reddy KD, Farh L, Rettew LM, Sanchez PR, Deschenes RJ. Mutations in the X-linked intellectual disability gene, zDHHC9, alter autopalmitoylation activity by distinct mechanisms. The Journal of Biological Chemistry. 289: 18582-92. PMID 24811172 DOI: 10.1074/Jbc.M114.567420  0.609
2012 Mitchell DA, Hamel LD, Ishizuka K, Mitchell G, Schaefer LM, Deschenes RJ. The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate. The Journal of Biological Chemistry. 287: 34337-48. PMID 22904317 DOI: 10.1074/Jbc.M112.379297  0.653
2012 Pedram A, Razandi M, Deschenes RJ, Levin ER. DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors. Molecular Biology of the Cell. 23: 188-99. PMID 22031296 DOI: 10.1091/Mbc.E11-07-0638  0.362
2010 Mitchell DA, Mitchell G, Ling Y, Budde C, Deschenes RJ. Mutational analysis of Saccharomyces cerevisiae Erf2 reveals a two-step reaction mechanism for protein palmitoylation by DHHC enzymes. The Journal of Biological Chemistry. 285: 38104-14. PMID 20851885 DOI: 10.1074/Jbc.M110.169102  0.39
2010 Vinnakota KC, Mitchell DA, Deschenes RJ, Wakatsuki T, Beard DA. Analysis of the diffusion of Ras2 in Saccharomyces cerevisiae using fluorescence recovery after photobleaching. Physical Biology. 7: 026011. PMID 20526029 DOI: 10.1088/1478-3975/7/2/026011  0.333
2009 Jennings BC, Nadolski MJ, Ling Y, Baker MB, Harrison ML, Deschenes RJ, Linder ME. 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. Journal of Lipid Research. 50: 233-42. PMID 18827284 DOI: 10.1194/Jlr.M800270-Jlr200  0.355
2008 Shankarnarayan S, Narang SS, Malone CL, Deschenes RJ, Fassler JS. Modulation of yeast Sln1 kinase activity by the CCW12 cell wall protein. The Journal of Biological Chemistry. 283: 1962-73. PMID 18048366 DOI: 10.1074/Jbc.M706877200  0.459
2008 Maikeng H, Jackson A, Bradley T, Hassan H, Lee A, Lee T, Brookens Q, Donahoe J, Jimenez J, Caldwell K, Hurtado D, Montes E, Moua I, Xiong A, Anderson J, ... Deschenes RJ, et al. Construction of a physical model of a farnesyltransferase‐inhibitor complex: Insight into a novel therapy for Hutchinson‐Guilford Progeria The Faseb Journal. 22: 342-342. DOI: 10.1096/Fasebj.22.2_Supplement.342  0.307
2008 Shankarnarayan S, Malone CL, Deschenes RJ, Fassler JS. Modulation of yeast Sln1 kinase activity by the Ccw12 cell wall protein (Journal of Biological Chemistry (2008) 283 (1962-1973)) Journal of Biological Chemistry. 283: 23496.  0.315
2007 Linder ME, Deschenes RJ. Palmitoylation: policing protein stability and traffic. Nature Reviews. Molecular Cell Biology. 8: 74-84. PMID 17183362 DOI: 10.1038/Nrm2084  0.438
2006 Budde C, Schoenfish MJ, Linder ME, Deschenes RJ. Purification and characterization of recombinant protein acyltransferases. Methods (San Diego, Calif.). 40: 143-50. PMID 17012026 DOI: 10.1016/J.Ymeth.2006.07.017  0.46
2006 Mitchell DA, Vasudevan A, Linder ME, Deschenes RJ. Protein palmitoylation by a family of DHHC protein S-acyltransferases. Journal of Lipid Research. 47: 1118-27. PMID 16582420 DOI: 10.1194/Jlr.R600007-Jlr200  0.497
2006 Wang G, Deschenes RJ. Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae. Molecular and Cellular Biology. 26: 3243-55. PMID 16581797 DOI: 10.1128/Mcb.26.8.3243-3255.2006  0.577
2005 Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, Linder ME. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. The Journal of Biological Chemistry. 280: 31141-8. PMID 16000296 DOI: 10.1074/Jbc.M504113200  0.467
2004 Lu JM, Deschenes RJ, Fassler JS. Role for the Ran binding protein, Mog1p, in Saccharomyces cerevisiae SLN1-SKN7 signal transduction. Eukaryotic Cell. 3: 1544-56. PMID 15590828 DOI: 10.1128/Ec.3.6.1544-1556.2004  0.443
2004 Babu P, Deschenes RJ, Robinson LC. Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting. The Journal of Biological Chemistry. 279: 27138-47. PMID 15105419 DOI: 10.1074/Jbc.M403071200  0.384
2004 Linder ME, Deschenes RJ. Model organisms lead the way to protein palmitoyltransferases. Journal of Cell Science. 117: 521-6. PMID 14730009 DOI: 10.1242/Jcs.00989  0.496
2003 Lu JM, Deschenes RJ, Fassler JS. Saccharomyces cerevisiae histidine phosphotransferase Ypd1p shuttles between the nucleus and cytoplasm for SLN1-dependent phosphorylation of Ssk1p and Skn7p. Eukaryotic Cell. 2: 1304-14. PMID 14665464 DOI: 10.1128/Ec.2.6.1304-1314.2003  0.456
2003 Dong X, Mitchell DA, Lobo S, Zhao L, Bartels DJ, Deschenes RJ. Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae. Molecular and Cellular Biology. 23: 6574-84. PMID 12944483 DOI: 10.1128/Mcb.23.18.6574-6584.2003  0.708
2003 Linder ME, Deschenes RJ. New insights into the mechanisms of protein palmitoylation. Biochemistry. 42: 4311-20. PMID 12693927 DOI: 10.1021/Bi034159A  0.45
2002 Ault AD, Fassler JS, Deschenes RJ. Altered phosphotransfer in an activated mutant of the Saccharomyces cerevisiae two-component osmosensor Sln1p. Eukaryotic Cell. 1: 174-80. PMID 12455952 DOI: 10.1128/Ec.1.2.174-180.2002  0.705
2002 Zhao L, Lobo S, Dong X, Ault AD, Deschenes RJ. Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins. The Journal of Biological Chemistry. 277: 49352-9. PMID 12379641 DOI: 10.1074/Jbc.M209760200  0.757
2002 Lobo S, Greentree WK, Linder ME, Deschenes RJ. Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 277: 41268-73. PMID 12193598 DOI: 10.1074/Jbc.M206573200  0.461
2002 Tao W, Malone CL, Ault AD, Deschenes RJ, Fassler JS. A cytoplasmic coiled-coil domain is required for histidine kinase activity of the yeast osmosensor, SLN1. Molecular Microbiology. 43: 459-73. PMID 11985722 DOI: 10.1046/J.1365-2958.2002.02757.X  0.699
2002 Li S, Dean S, Li Z, Horecka J, Deschenes RJ, Fassler JS. The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p. Molecular Biology of the Cell. 13: 412-24. PMID 11854400 DOI: 10.1091/Mbc.01-09-0434  0.381
2000 Zhan XL, Hong Y, Zhu T, Mitchell AP, Deschenes RJ, Guan KL. Essential functions of protein tyrosine phosphatases PTP2 and PTP3 and RIM11 tyrosine phosphorylation in Saccharomyces cerevisiae meiosis and sporulation. Molecular Biology of the Cell. 11: 663-76. PMID 10679022 DOI: 10.1091/Mbc.11.2.663  0.59
1999 Bartels DJ, Mitchell DA, Dong X, Deschenes RJ. Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae. Molecular and Cellular Biology. 19: 6775-87. PMID 10490616 DOI: 10.1128/Mcb.19.10.6775  0.699
1999 Deschenes RJ, Lin H, Ault AD, Fassler JS. Antifungal properties and target evaluation of three putative bacterial histidine kinase inhibitors. Antimicrobial Agents and Chemotherapy. 43: 1700-3. PMID 10390225 DOI: 10.1128/Aac.43.7.1700  0.684
1999 Tao W, Deschenes RJ, Fassler JS. Intracellular glycerol levels modulate the activity of Sln1p, a Saccharomyces cerevisiae two-component regulator Journal of Biological Chemistry. 274: 360-367. PMID 9867851 DOI: 10.1074/Jbc.274.1.360  0.428
1998 Li S, Ault A, Malone CL, Raitt D, Dean S, Johnston LH, Deschenes RJ, Fassler JS. The yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p. The Embo Journal. 17: 6952-62. PMID 9843501 DOI: 10.1093/Emboj/17.23.6952  0.711
1997 Kurth DD, Farh L, Deschenes RJ. Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase β-subunit Ram1(dpr1) Biochemistry. 36: 15932-15939. PMID 9398327 DOI: 10.1021/Bi971614S  0.445
1997 Zhan XL, Deschenes RJ, Guan KL. Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae. Genes & Development. 11: 1690-702. PMID 9224718 DOI: 10.1101/Gad.11.13.1690  0.56
1997 Fassler JS, Gray WM, Malone CL, Tao W, Lin H, Deschenes RJ. Activated alleles of yeast SLN1 increase Mcm1-dependent reporter gene expression and diminish signaling through the Hog1 osmosensing pathway. The Journal of Biological Chemistry. 272: 13365-71. PMID 9148959 DOI: 10.1074/Jbc.272.20.13365  0.456
1997 Quinby GE, Deschenes RJ. An amino terminal prosequence is required for efficient synthesis of S. cerevisiae a-factor Biochimica Et Biophysica Acta - Molecular Cell Research. 1356: 23-34. PMID 9099988 DOI: 10.1016/S0167-4889(96)00153-X  0.311
1995 Farh L, Mitchell DA, Deschenes RJ. Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway. Archives of Biochemistry and Biophysics. 318: 113-21. PMID 7726551 DOI: 10.1006/Abbi.1995.1211  0.579
1995 Yu G, Deschenes RJ, Fassler JS. The essential transcription factor, Mcm1, is a downstream target of Sln1, a yeast 'two-component' regulator Journal of Biological Chemistry. 270: 8739-8743. PMID 7721779 DOI: 10.1074/Jbc.270.15.8739  0.405
1995 Mitchell DA, Deschenes RJ. Characterization of protein prenylation in Saccharomyces cerevisiae Methods in Enzymology. 250: 68-78. PMID 7651186 DOI: 10.1016/0076-6879(95)50063-4  0.432
1994 Mitchell DA, Farh L, Marshall TK, Deschenes RJ. A polybasic domain allows nonprenylated Ras proteins to function in Saccharomyces cerevisiae Journal of Biological Chemistry. 269: 21540-21546. PMID 8063791  0.399
1993 Mitchell DA, Marshall TK, Deschenes RJ. Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast Yeast. 9: 715-722. PMID 8368005 DOI: 10.1002/Yea.320090705  0.593
1993 Guan K, Farh L, Marshall TK, Deschenes RJ. Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene Current Genetics. 24: 141-148. PMID 7916673 DOI: 10.1007/Bf00324678  0.512
1992 Guan K, Deschenes RJ, Dixon JE. Isolation and characterization of a second protein tyrosine phosphatase gene, PTP2, from Saccharomyces cerevisiae Journal of Biological Chemistry. 267: 10024-10030. PMID 1577774  0.338
1991 Guan KL, Deschenes RJ, Qiu H, Dixon JE. Cloning and expression of a yeast protein tyrosine phosphatase. The Journal of Biological Chemistry. 266: 12964-70. PMID 1649172  0.642
1990 Stimmel JB, Deschenes RJ, Volker C, Stock J, Clarke S. Evidence for an S-farnesylcysteine methyl ester at the carboxyl terminus of the Saccharomyces cerevisiae RAS2 protein Biochemistry. 29: 9651-9659. PMID 2271607 DOI: 10.1021/Bi00493A021  0.455
1990 Fedor-Chaiken M, Deschenes RJ, Broach JR. SRV2, a gene required for RAS activation of adenylate cyclase in yeast Cell. 61: 329-340. PMID 2158860 DOI: 10.1016/0092-8674(90)90813-T  0.63
1990 Broach JR, Deschenes RJ. The function of ras genes in Saccharomyces cerevisiae Advances in Cancer Research. 54: 79-139. PMID 2153328 DOI: 10.1016/S0065-230X(08)60809-X  0.661
1990 Deschenes RJ, Resh MD, Broach JR. Acylation and prenylation of proteins Current Opinion in Cell Biology. 2: 1108-1113. PMID 2099805 DOI: 10.1016/0955-0674(90)90164-A  0.608
1989 Deschenes RJ, Stimmel JB, Clarke S, Stock J, Broach JR. RAS2 protein of Saccharomyces cerevisiae is methyl-esterified at its carboxyl terminus Journal of Biological Chemistry. 264: 11865-11873. PMID 2663844  0.633
1988 Clarke S, Vogel JP, Deschenes RJ, Stock J. Posttranslational modification of the Ha-ras oncogene protein: Evidence for a third class of protein carboxyl methyltransferases Proceedings of the National Academy of Sciences of the United States of America. 85: 4643-4647. PMID 3290900 DOI: 10.1073/Pnas.85.13.4643  0.432
1987 Deschenes RJ, Broach JR. Fatty acylation is important but not essential for Saccharomyces cerevisiae RAS function Molecular and Cellular Biology. 7: 2344-2351. PMID 3302674 DOI: 10.1128/Mcb.7.7.2344  0.674
1985 Deschenes RJ, Narayana SVL, Argos P, Dixon JE. Primary structural comparison of the preprohormones cholecystokinin and gastrin Febs Letters. 182: 135-138. PMID 3972119 DOI: 10.1016/0014-5793(85)81170-4  0.485
1984 Deschenes RJ, Lorenz LJ, Haun RS, Roos BA, Collier KJ, Dixon JE. Cloning and sequence analysis of a cDNA encoding rat preprocholecystokinin Proceedings of the National Academy of Sciences of the United States of America. 81: 726-730. PMID 6199787 DOI: 10.1073/Pnas.81.3.726  0.471
1982 Magazin M, Minth CD, Funckes CL, Deschenes R, Tavianini MA, Dixon JE. Sequence of a cDNA encoding pancreatic preprosomatostatin-22. Proceedings of the National Academy of Sciences of the United States of America. 79: 5152-6. PMID 6127673 DOI: 10.1073/Pnas.79.17.5152  0.475
1981 Taylor WL, Collier KJ, Deschenes RJ, Weith HL, Dixon JE. Sequence analysis of a cDNA coding for a pancreatic precursor to somatostatin Proceedings of the National Academy of Sciences of the United States of America. 78: 6694-4498. PMID 6171821 DOI: 10.1073/Pnas.78.11.6694  0.471
Show low-probability matches.