Louis R. Barrows - Publications

Affiliations: 
University of Utah, Salt Lake City, UT 
Area:
Pharmacology, Toxicology, Biochemistry

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lim AL, Moos P, Pond CD, Larson EC, Martins LJ, Szaniawski MA, Planelles V, Barrows LR. HIV-1 provirus transcription and translation in macrophages differs from pre-integrated cDNA complexes and requires E2F transcriptional programs. Virulence. 13: 386-413. PMID 35166645 DOI: 10.1080/21505594.2022.2031583  0.636
2020 Larson EC, Lim AL, Pond CD, Craft M, Čavužić M, Waldrop GL, Schmidt EW, Barrows LR. Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase. Plos One. 15: e0233485. PMID 32470050 DOI: 10.1371/Journal.Pone.0233485  0.673
2020 Looper RE, Serrano CM, Kannareddy HR, Eiler D, Koch M, Tresco BIC, Barrows LR, Vanderlinden RT, Testa CA, Sebahar PR. Unifying the aminohexopyranose- and peptidyl-nucleoside antibiotcs; implications for antibiotic design. Angewandte Chemie (International Ed. in English). PMID 32342623 DOI: 10.1002/Anie.202003094  0.312
2018 Smith TE, Pond CD, Pierce E, Harmer ZP, Kwan J, Zachariah MM, Harper MK, Wyche TP, Matainaho TK, Bugni TS, Barrows LR, Ireland CM, Schmidt EW. Accessing chemical diversity from the uncultivated symbionts of small marine animals. Nature Chemical Biology. PMID 29291350 DOI: 10.1038/Nchembio.2537  0.677
2017 Larson EC, Novis CL, Martins LJ, Macedo AB, Kimball KE, Bosque A, Planelles V, Barrows LR. Mycobacterium tuberculosis reactivates latent HIV-1 in T cells in vitro. Plos One. 12: e0185162. PMID 28949981 DOI: 10.1371/Journal.Pone.0185162  0.319
2017 Issac M, Aknin M, Gauvin-Bialecki A, Pond CD, Barrows LR, Kashman Y, Carmeli S. Mollecarbamates, Molleureas, and Molledihydroisoquinolone, o-Carboxyphenethylamide Metabolites of the Ascidian Didemnum molle Collected in Madagascar. Journal of Natural Products. PMID 28574260 DOI: 10.1021/Acs.Jnatprod.7B00123  0.675
2016 Larson EC, Pond CD, Rai PP, Matainaho TK, Piskaut P, Franklin MR, Barrows LR. Traditional Preparations and Methanol Extracts of Medicinal Plants from Papua New Guinea Exhibit Similar Cytochrome P450 Inhibition. Evidence-Based Complementary and Alternative Medicine : Ecam. 2016: 7869710. PMID 27642356 DOI: 10.1155/2016/7869710  0.679
2016 Larson EC, Pond CD, Szaniawski MA, Martins LJ, Planelles V, Barrows LR. Macrophage Cell Coinfected with HIV-1 and H37Ra. Aids Research and Human Retroviruses. PMID 27309672 DOI: 10.1089/Aid.2016.0067  0.65
2015 Larson E, Pond C, Rai P, Matainaho T, Piskaut P, Barrows L, Franklin M. Traditional preparations and methanolic extracts of plants from Papua New Guinea exhibit similar cytochrome P450 inhibition Planta Medica. 81. DOI: 10.1055/S-0035-1556440  0.695
2015 Pond C, Rai P, Barrows L, Matainaho T. HIV inhibitory activity from Papua New Guinean medicinal plants Planta Medica. 81. DOI: 10.1055/S-0035-1556333  0.68
2015 Rai P, Matainaho T, Barrows L. Medicinal plants used by traditional medicine practitioners for the treatment of HIV/AIDS and related conditions in Papua New Guinea Planta Medica. 81. DOI: 10.1055/S-0035-1556100  0.32
2014 Jadulco RC, Koch M, Kakule TB, Schmidt EW, Orendt A, He H, Janso JE, Carter GT, Larson EC, Pond C, Matainaho TK, Barrows LR. Isolation of pyrrolocins A-C: cis- and trans-decalin tetramic acid antibiotics from an endophytic fungal-derived pathway. Journal of Natural Products. 77: 2537-44. PMID 25351193 DOI: 10.1021/Np500617U  0.677
2014 Larson EC, Hathaway LB, Lamb JG, Pond CD, Rai PP, Matainaho TK, Piskaut P, Barrows LR, Franklin MR. Interactions of Papua New Guinea medicinal plant extracts with antiretroviral therapy. Journal of Ethnopharmacology. 155: 1433-40. PMID 25138353 DOI: 10.1016/J.Jep.2014.07.023  0.675
2014 Jadulco RC, Pond CD, Van Wagoner RM, Koch M, Gideon OG, Matainaho TK, Piskaut P, Barrows LR. 4-Quinolone alkaloids from Melochia odorata. Journal of Natural Products. 77: 183-7. PMID 24392742 DOI: 10.1021/Np400847T  0.693
2014 Lu Z, Van Wagoner RM, Pond CD, Pole AR, Jensen JB, Blankenship D, Grimberg BT, Kiapranis R, Matainaho TK, Barrows LR, Ireland CM. Myristicyclins A and B: antimalarial procyanidins from Horsfieldia spicata from Papua New Guinea. Organic Letters. 16: 346-9. PMID 24350818 DOI: 10.1021/Ol4022639  0.692
2014 Lin Z, Koch M, Pond CD, Mabeza G, Seronay RA, Concepcion GP, Barrows LR, Olivera BM, Schmidt EW. Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp. The Journal of Antibiotics. 67: 121-6. PMID 24220110 DOI: 10.1038/Ja.2013.115  0.692
2013 Lu Z, Koch M, Harper MK, Matainaho TK, Barrows LR, Van Wagoner RM, Ireland CM. Plakinamine M, a steroidal alkaloid from the marine sponge Corticium sp. Journal of Natural Products. 76: 2150-2. PMID 24195491 DOI: 10.1021/Np400649E  0.364
2013 Pond C, Rai P, Matainaho T, Piskaut P, Larson E, Franklin M, Martins L, Planelles V, Barrows L. Interactions of Tropical Pacific Medicinal Plants with HIV and Anti-Retroviral Drugs Planta Medica. 79. DOI: 10.1055/S-0033-1348603  0.667
2012 Lu Z, Harper MK, Pond CD, Barrows LR, Ireland CM, Van Wagoner RM. Thiazoline peptides and a tris-phenethyl urea from Didemnum molle with anti-HIV activity. Journal of Natural Products. 75: 1436-40. PMID 22845329 DOI: 10.1021/Np300270P  0.701
2011 Jadulco RC, Koch M, Van Wagoner RM, Pond C, Gideon OG, Matainaho T, Piskaut P, Barrows LR. New antimycobacterial triterpenoids from Rhus taitensis. Planta Medica. 77: 1651-4. PMID 21544777 DOI: 10.1055/S-0030-1271027  0.676
2009 Barrows LR, Matainaho TK, Ireland CM, Miller S, Carter GT, Bugni T, Rai P, Gideon O, Manoka B, Piskaut P, Banka R, Kiapranis R, Noro JN, Pond CD, Andjelic CD, et al. Making the most of Papua New Guinea's biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in "The Land of the Unexpected" Pharmaceutical Biology. 47: 795-808. PMID 20016761 DOI: 10.1080/13880200902991599  0.625
2009 Marshall KM, Andjelic CD, Tasdemir D, Concepción GP, Ireland CM, Barrows LR. Deoxyamphimedine, a pyridoacridine alkaloid, damages DNA via the production of reactive oxygen species. Marine Drugs. 7: 196-209. PMID 19597581 DOI: 10.3390/Md7020196  0.661
2009 Koch M, Bugni TS, Pond CD, Sondossi M, Dindi M, Piskaut P, Ireland CM, Barrows LR. Antimycobacterial activity of Exocarpos latifolius is due to exocarpic acid. Planta Medica. 75: 1326-30. PMID 19444772 DOI: 10.1055/S-0029-1185687  0.664
2009 Bugni TS, Andjelic CD, Pole AR, Rai P, Ireland CM, Barrows LR. Biologically active components of a Papua New Guinea analgesic and anti-inflammatory lichen preparation. Fitoterapia. 80: 270-3. PMID 19289158 DOI: 10.1016/J.Fitote.2009.03.003  0.344
2008 Andjelic CD, Planelles V, Barrows LR. Characterizing the anti-HIV activity of papuamide A. Marine Drugs. 6: 528-49. PMID 19172193 DOI: 10.3390/Md20080027  0.32
2008 Noro JC, Barrows LR, Gideon OG, Ireland CM, Koch M, Matainaho T, Piskaut P, Pond CD, Bugni TS. Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis. Journal of Natural Products. 71: 1623-4. PMID 18710283 DOI: 10.1021/Np800082E  0.686
2007 Barrows LR, Powan E, Pond CD, Matainaho T. Anti-TB activity of Evodia elleryana bark extract. Fitoterapia. 78: 250-2. PMID 17350179 DOI: 10.1016/J.Fitote.2006.12.001  0.667
2006 Ratnayake AS, Bugni TS, Feng X, Harper MK, Skalicky JJ, Mohammed KA, Andjelic CD, Barrows LR, Ireland CM. Theopapuamide, a cyclic depsipeptide from a Papua New Guinea lithistid sponge Theonella swinhoei. Journal of Natural Products. 69: 1582-6. PMID 17125225 DOI: 10.1021/Np060229D  0.315
2006 Pond CD, Marshall KM, Barrows LR. Identification of a small topoisomerase I-binding peptide that has synergistic antitumor activity with 9-aminocamptothecin. Molecular Cancer Therapeutics. 5: 739-45. PMID 16546989 DOI: 10.1158/1535-7163.Mct-05-0377  0.755
2005 Dijoux MG, Schnabel PC, Hallock YF, Boswell JL, Johnson TR, Wilson JA, Ireland CM, van Soest R, Boyd MR, Barrows LR, Cardellina JH. Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus Zyzzya. Bioorganic & Medicinal Chemistry. 13: 6035-44. PMID 16009557 DOI: 10.1016/J.Bmc.2005.06.019  0.772
2005 Ratnayake AS, Davis RA, Harper MK, Veltri CA, Andjelic CD, Barrows LR, Ireland CM. Aurantosides G, H, and I: three new tetramic acid glycosides from a Papua New Guinea Theonella swinhoei. Journal of Natural Products. 68: 104-7. PMID 15679329 DOI: 10.1021/Np049721S  0.331
2004 Marshall KM, Barrows LR. Biological activities of pyridoacridines. Natural Product Reports. 21: 731-51. PMID 15565252 DOI: 10.1039/B401662A  0.617
2004 Marshall KM, Holden JA, Koller A, Kashman Y, Copp BR, Barrows LR. AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex. Anti-Cancer Drugs. 15: 907-13. PMID 15457132 DOI: 10.1097/00001813-200410000-00012  0.676
2004 Antunes EM, Beukes DR, Kelly M, Samaai T, Barrows LR, Marshall KM, Sincich C, Davies-Coleman MT. Cytotoxic pyrroloiminoquinones from four new species of South African latrunculid sponges. Journal of Natural Products. 67: 1268-76. PMID 15332840 DOI: 10.1021/Np034084B  0.683
2003 Marshall KM, Matsumoto SS, Holden JA, Concepción GP, Tasdemir D, Ireland CM, Barrows LR. The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine. Biochemical Pharmacology. 66: 447-58. PMID 12907244 DOI: 10.1016/S0006-2952(03)00209-0  0.678
2003 Matsumoto SS, Biggs J, Copp BR, Holden JA, Barrows LR. Mechanism of ascididemin-induced cytotoxicity. Chemical Research in Toxicology. 16: 113-22. PMID 12588181 DOI: 10.1021/Tx025618W  0.393
2002 Edler MC, Fernandez AM, Lassota P, Ireland CM, Barrows LR. Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10. Biochemical Pharmacology. 63: 707-15. PMID 11992639 DOI: 10.1016/S0006-2952(01)00898-X  0.711
2001 Tasdemir D, Marshall KM, Mangalindan GC, Concepción GP, Barrows LR, Harper MK, Ireland CM. Deoxyamphimedine, a new pyridoacridine alkaloid from two tropical Xestospongia sponges. The Journal of Organic Chemistry. 66: 3246-8. PMID 11325300 DOI: 10.1021/Jo010153K  0.659
2000 Matsumoto SS, Sidford MH, Holden JA, Barrows LR, Copp BR. Mechanism of action studies of cytotoxic marine alkaloids: Ascididemin exhibits thiol-dependent oxidative DNA cleavage Tetrahedron Letters. 41: 1667-1670. DOI: 10.1016/S0040-4039(00)00011-3  0.38
1999 Pond CD, Li XG, Rubin EH, Barrows LR. Effects of mutations in the F361 to R364 region of topoisomerase I (Topo I), in the presence and absence of 9-aminocamptothecin, on the Topo I-DNA interaction. Anti-Cancer Drugs. 10: 647-53. PMID 10507314 DOI: 10.1097/00001813-199908000-00004  0.644
1999 Matsumoto SS, Haughey HM, Schmehl DM, Venables DA, Ireland CM, Holden JA, Barrows LR. Makaluvamines vary in ability to induce dose-dependent DNA cleavage via topoisomerase II interaction Anti-Cancer Drugs. 10: 39-45. PMID 10194546 DOI: 10.1097/00001813-199901000-00006  0.377
1999 De Guzman FS, Carte B, Troupe N, Faulkner DJ, Harper MK, Concepcion GP, Mangalindan GC, Matsumoto SS, Barrows LR, Ireland CM. Neoamphimedine: A new pyridoacridine topoisomerase II inhibitor which catenates DNA Journal of Organic Chemistry. 64: 1400-1402. DOI: 10.1021/Jo982047X  0.352
1998 Barrows LR, Holden JA, Anderson M, D'Arpa P. The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication Mutation Research - Dna Repair. 408: 103-110. PMID 9739812 DOI: 10.1016/S0921-8777(98)00022-6  0.374
1997 Pond CD, Holden JA, Schnabel PC, Barrows LR. Surface plasmon resonance analysis of topoisomerase I-DNA binding: effect of Mg2+ and DNA sequence. Anti-Cancer Drugs. 8: 336-44. PMID 9180386 DOI: 10.1097/00001813-199704000-00005  0.723
1997 Venables DA, Concepción GP, Matsumoto SS, Barrows LR, Ireland CM. Makaluvamine N: A new pyrroloiminoquinone from Zyzzya fuliginosa Journal of Natural Products. 60: 408-410. PMID 9134749 DOI: 10.1021/Np9607262  0.335
1997 Venables DA, Barrows LR, Lassota P, Ireland CM. Veiutamine. A new alkaloid from the Fijian sponge Zyzzya fuliginosa Tetrahedron Letters. 38: 721-722. DOI: 10.1016/S0040-4039(96)02424-0  0.319
1996 Kokoshka JM, Capson TL, Holden JA, Ireland CM, Barrows LR. Differences in the topoisomerase I cleavage complexes formed by camptothecin and wakayin, a DNA-intercalating marine natural product. Anti-Cancer Drugs. 7: 758-65. PMID 8949987 DOI: 10.1097/00001813-199609000-00007  0.382
1996 Donkor IO, Devraj R, Queener SF, Barrows LR, Gangjee A. Synthesis of a Series of Diaminobenzo[f]- And Diaminobenzo[h]pyrimido[4,5-b]quinolines as 5-Deaza Tetracyclic Nonclassical Antifolates Journal of Heterocyclic Chemistry. 33: 1653-1660. DOI: 10.1002/Jhet.5570330618  0.308
1995 Warters RL, Barrows LR, Chen DJ. DNA double-strand break repair in two radiation-sensitive mouse mammary carcinoma cell lines Mutation Research-Dna Repair. 336: 1-7. PMID 7528891 DOI: 10.1016/0921-8777(94)00036-6  0.338
1995 Concepción GP, Foderaro TA, Eldredge GS, Lobkovsky E, Clardy J, Barrows LR, Ireland CM. Topoisomerase II-mediated DNA cleavage by adocia- and xestoquinones from the Philippine sponge Xestospongia sp Journal of Medicinal Chemistry. 38: 4503-4507. PMID 7473578 DOI: 10.1021/Jm00022A016  0.412
1995 Lindsay BS, Barrows LR, Copp BR. Structural requirements for biological activity of the marine alkaloid ascididemin Bioorganic and Medicinal Chemistry Letters. 5: 739-742. DOI: 10.1016/0960-894X(95)00106-4  0.351
1994 Warters RL, Barrows LR. Heat sensitivity of HeLa S3 cell DNA topoisomerase II Journal of Cellular Physiology. 159: 468-474. PMID 8188763 DOI: 10.1002/Jcp.1041590311  0.346
1994 Swaffar DS, Ireland CM, Barrows LR. A rapid mechanism-based screen to detect potential anti-cancer agents Anti-Cancer Drugs. 5: 15-23. PMID 8186425 DOI: 10.1097/00001813-199402000-00003  0.426
1994 Gangjee A, Devraj R, McGuire JJ, Kisliuk RL, Queener SF, Barrows LR. Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: Synthesis and biological activities Journal of Medicinal Chemistry. 37: 1169-1176. PMID 8164259 DOI: 10.1021/Jm00034A015  0.369
1994 Meegalla SK, Stevens GJ, McQueen CA, Chen AY, Yu C, Liu LF, Barrows LR, LaVoie EJ. Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin Journal of Medicinal Chemistry. 37: 3434-3439. PMID 7932571 DOI: 10.1021/Jm00046A028  0.393
1994 Weinkauf RL, Chen AY, Yu C, Liu L, Barrows L, LaVoie EJ. Antineoplastic activity of benzimidazo[1,2-b]-isoquinolines, indolo[2,3-b]quinolines, and pyridocarbazoles Bioorganic and Medicinal Chemistry. 2: 781-786. PMID 7894971 DOI: 10.1016/S0968-0896(00)82177-X  0.335
1994 McDonald LA, Eldredge GS, Barrows LR, Ireland CM. Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: A mechanism for the apparent intercalator-induced inhibition of topoisomerase II Journal of Medicinal Chemistry. 37: 3819-3827. PMID 7525959 DOI: 10.1021/Jm00048A017  0.43
1993 Barrows LR, Radisky DC, Copp BR, Swaffar DS, Kramer RA, Warters RL, Ireland CM. Makaluvamines, marine natural products, are active anti-cancer agents and DNA topo II inhibitors Anti-Cancer Drug Design. 8: 333-347. PMID 8251041  0.316
1993 Gangjee A, Shi J, Queener SF, Barrows LR, Kisliuk RL. Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents Journal of Medicinal Chemistry®. 36: 3437-3443. PMID 8230134 DOI: 10.1021/Jm00074A026  0.306
1993 Radisky DC, Radisky ES, Barrows LR, Copp BR, Kramer RA, Ireland CM. Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya Journal of the American Chemical Society. 115: 1632-1638. DOI: 10.1021/Ja00058A003  0.419
1992 Copp BR, Ireland CM, Barrows LR. Psammaplysin C: A new cytotoxic dibromotyrosine-derived metabolite from the marine sponge Druinella (=Psammaplysilla) purpurea Journal of Natural Products. 55: 822-823. PMID 1522422 DOI: 10.1021/Np50084A021  0.372
1991 Barrows LR, Paxton MB, Kennedy KA, Thompson LH. Characterization of revertants of the CHO EM9 mutant arising during DNA transfection Carcinogenesis. 12: 805-811. PMID 2029744 DOI: 10.1093/Carcin/12.5.805  0.316
1991 Morrey JD, Bourn SM, Bunch TD, Jackson MK, Sidwell RW, Barrows LR, Daynes RA, Rosen CA. In vivo activation of human immunodeficiency virus type 1 long terminal repeat by UV type A (UA-A) light plus psoralen and UV-B light in the skin of transgenic mice Journal of Virology. 65: 5045-5051. PMID 1908029 DOI: 10.1128/Jvi.65.9.5045-5051.1991  0.309
1991 Swersey JC, Barrows LR, Ireland CM. Mamanuthaquinone: an antimicrobial and cytotoxic metabolite of Fasciospongia sp Tetrahedron Letters. 32: 6687-6690. DOI: 10.1016/S0040-4039(00)93575-5  0.354
1987 Barrows LR, Borchers AH, Paxton MB. Transfectant CHO cells expressing O6-alkylguanine-DNA-alkyltransferase display increased resistance to DNA damage other than O6-guanine alkylation Carcinogenesis. 8: 1853-1859. PMID 2824084 DOI: 10.1093/Carcin/8.12.1853  0.337
1986 Spiro IJ, Barrows LR, Kennedy KA, Ling CC. Transfection of a human gene for the repair of X-ray- and EMS-induced DNA damage Radiation Research. 108: 146-157. PMID 3786675 DOI: 10.2307/3576820  0.348
1986 Barrows LR. Methylation of DNA guanine via the 1-carbon pool in dimethylnitrosamine-treated rats Mutation Research Letters. 173: 73-79. PMID 3510380 DOI: 10.1016/0165-7992(86)90014-X  0.327
1983 Barrows LR, Shank RC, Magee PN. S-adenosylmethionine metabolism and DNA methylation in hydrazine-treated rats Carcinogenesis. 4: 953-957. PMID 6872153 DOI: 10.1093/Carcin/4.8.953  0.329
1982 Barrows LR, Gombar CT, Magee PN. Mutation, DNA labeling, and transformation of BHK-21/CL 13 cells by MNNG, and nitrosocimetidine Mutation Research/Genetic Toxicology. 102: 145-158. PMID 7144776 DOI: 10.1016/0165-1218(82)90115-X  0.321
1982 Barrows LR, Magee PN. Nonenzymatic methylation of dna by s-adenosylmethionine in vitro Carcinogenesis. 3: 349-351. PMID 7083475 DOI: 10.1093/Carcin/3.3.349  0.331
1981 Barrows LR, Shank RC. Aberrant methylation of liver DNA in rats during hepatotoxicity Toxicology and Applied Pharmacology. 60: 334-345. PMID 7281192 DOI: 10.1016/0041-008X(91)90236-8  0.301
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