Hedley C. Freake - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Animal Culture and Nutrition Agriculture, Molecular Biology, Biochemistry

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Sankavaram K, Chong L, Bruno RS, Freake HC. Zinc status alters growth and oxidative stress responses in rat hepatoma cells. Nutrition and Cancer. 66: 104-16. PMID 24325217 DOI: 10.1080/01635581.2014.851713  0.756
2012 Grattan BJ, Freake HC. Zinc and cancer: implications for LIV-1 in breast cancer. Nutrients. 4: 648-75. PMID 22852056 DOI: 10.3390/Nu4070648  0.319
2012 Sankavaram K, Freake HC. The effects of transformation and ZnT-1 silencing on zinc homeostasis in cultured cells. The Journal of Nutritional Biochemistry. 23: 629-34. PMID 21775119 DOI: 10.1016/J.Jnutbio.2011.03.006  0.774
2011 Dutta A, Sankavaram K, Chong L, Palermo A, Michel RG, Freake HC. Rapid homeostatic response of H4IIE cells to diethylenetriaminepentaacetic acid is not due to changes in the amount or localization of ZnT-1 protein. Nutrition Research (New York, N.Y.). 31: 404-11. PMID 21636019 DOI: 10.1016/J.Nutres.2011.05.001  0.767
2010 Dutta A, Schaller M, Franco AT, Sankavaram K, Grattan BJ, Freake HC. Zinc retention differs between primary and transformed cells in response to zinc deprivation. The Journal of Nutritional Biochemistry. 21: 162-70. PMID 19269154 DOI: 10.1016/J.Jnutbio.2008.12.008  0.774
2008 Lee MS, Park JY, Freake H, Kwun IS, Kim Y. Green tea catechin enhances cholesterol 7alpha-hydroxylase gene expression in HepG2 cells. The British Journal of Nutrition. 99: 1182-5. PMID 18533286 DOI: 10.1017/S0007114507864816  0.425
2007 Dutta A, Grattan B, Sankavaram K, Freake HC. Cultured cells differ in their homeostatic response to zinc deprivation The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A170-B  0.714
2006 Aggarwal D, Freake HC, Soliman GA, Dutta A, Fernandez ML. Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism. Lipids in Health and Disease. 5: 22. PMID 16911794 DOI: 10.1186/1476-511X-5-22  0.35
2005 Kim YJ, Lee MS, Lee HJ, Wu Y, Freake HC, Chun HS, Kim Y. Hormones and nutrients regulate acetyl-CoA carboxylase promoter I in rat primary hepatocytes. Journal of Nutritional Science and Vitaminology. 51: 124-8. PMID 16022200 DOI: 10.3177/Jnsv.51.124  0.405
2005 Patalay M, Lofgren IE, Freake HC, Koo SI, Fernandez ML. The lowering of plasma lipids following a weight reduction program is related to increased expression of the LDL receptor and lipoprotein lipase. The Journal of Nutrition. 135: 735-9. PMID 15795426 DOI: 10.1093/Jn/135.4.735  0.313
2005 Lim NC, Schuster JV, Porto MC, Tanudra MA, Yao L, Freake HC, Brückner C. Coumarin-based chemosensors for zinc(II): toward the determination of the design algorithm for CHEF-type and ratiometric probes. Inorganic Chemistry. 44: 2018-30. PMID 15762729 DOI: 10.1021/Ic048905R  0.365
2004 Sciaudone MP, Yao L, Schaller M, Zinn SA, Freake HC. Diethylenetriaminepentaacetic acid enhances thyroid hormone action by a transcriptional mechanism. Biological Trace Element Research. 99: 219-31. PMID 15235154 DOI: 10.1385/Bter:99:1-3:219  0.695
2003 Freake HC, Moon YK. Hormonal and nutritional regulation of lipogenic enzyme mRNA levels in rat primary white and brown adipocytes Journal of Nutritional Science and Vitaminology. 49: 40-46. PMID 12882395 DOI: 10.3177/Jnsv.49.40  0.475
2003 Lim NC, Yao L, Freake HC, Brückner C. Synthesis of a fluorescent chemosensor suitable for the imaging of zinc(II) in live cells. Bioorganic & Medicinal Chemistry Letters. 13: 2251-4. PMID 12824012 DOI: 10.1016/S0960-894X(03)00464-5  0.36
2003 Vega-López S, Freake HC, Fernandez ML. Sex and hormonal status modulate the effects of psyllium on plasma lipids and monocyte gene expression in humans. The Journal of Nutrition. 133: 67-70. PMID 12514268 DOI: 10.1093/Jn/133.1.67  0.374
2002 Roy S, Freake HC, Fernandez ML. Gender and hormonal status affect the regulation of hepatic cholesterol 7alpha-hydroxylase activity and mRNA abundance by dietary soluble fiber in the guinea pig. Atherosclerosis. 163: 29-37. PMID 12048119 DOI: 10.1016/S0021-9150(01)00749-3  0.327
2001 O'Callaghan BL, Koo SH, Wu Y, Freake HC, Towle HC. Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes. The Journal of Biological Chemistry. 276: 16033-9. PMID 11340083 DOI: 10.1074/Jbc.M101557200  0.372
2001 Freake HC, Govoni KE, Guda K, Huang C, Zinn SA. Actions and interactions of thyroid hormone and zinc status in growing rats Journal of Nutrition. 131: 1135-1141. PMID 11285315 DOI: 10.1093/Jn/131.4.1135  0.481
2000 Sciaudone MP, Chattopadhyay S, Freake HC. Chelation of zinc amplifies induction of growth hormone mRNA levels in cultured rat pituitary tumor cells. The Journal of Nutrition. 130: 158-63. PMID 10720163 DOI: 10.1093/Jn/130.2.158  0.691
1999 Conde K, Roy S, Freake HC, Newton RS, Fernandez ML. Atorvastatin and simvastatin have distinct effects on hydroxy methylglutaryl-CoA reductase activity and mRNA abundance in the guinea pig Lipids. 34: 1327-1332. PMID 10652993 DOI: 10.1007/S11745-999-0485-2  0.358
1998 Huang C, Freake HC. Thyroid hormone regulates the Acetyl-CoA carboxylase PI promoter Biochemical and Biophysical Research Communications. 249: 704-708. PMID 9731201 DOI: 10.1006/Bbrc.1998.9217  0.438
1998 Chattopadhyay S, Freake HC. Zinc chelation enhances thyroid hormone induction of growth hormone mRNA in GH3 cells Molecular and Cellular Endocrinology. 136: 151-157. PMID 9548219 DOI: 10.1016/S0303-7207(97)00228-1  0.58
1997 Chattopadhyay S, Freake HC. Zinc restriction stimulates thyroid hormone induced growth hormone gene expressioN in GH3 cells Faseb Journal. 11.  0.477
1996 Kim TS, Leahy P, Freake HC. Promoter usage determines tissue specific responsiveness of the rat acetyl-CoA carboxylase gene Biochemical and Biophysical Research Communications. 225: 647-653. PMID 8753813 DOI: 10.1006/Bbrc.1996.1224  0.391
1996 Chattopadhvay S, Freake HC. Dietylenetriaminepenta-acetic acid enhances thyroid hormone-induced growth hormone gene expression in cultured rat pituitary tumor cells Faseb Journal. 10.  0.495
1995 Freake HC, Oppenheimer JH. Thermogenesis and thyroid function Annual Review of Nutrition. 15: 263-291. PMID 8527221 DOI: 10.1146/Annurev.Nu.15.070195.001403  0.352
1995 Blennemann B, Leahy P, Kim TS, Freake HC. Tissue-specific regulation of lipogenic mRNAs by thyroid hormone Molecular and Cellular Endocrinology. 110: 1-8. PMID 7672439 DOI: 10.1016/0303-7207(95)03509-6  0.457
1993 Yeh WJ, Leahy P, Freake HC. Regulation of brown adipose tissue lipogenesis by thyroid hormone and the sympathetic nervous system American Journal of Physiology - Endocrinology and Metabolism. 265. PMID 8368294 DOI: 10.1152/Ajpendo.1993.265.2.E252  0.448
1992 Blennemann B, Moon YK, Freake HC. Tissue-specific regulation of fatty acid synthesis by thyroid hormone Endocrinology. 130: 637-643. PMID 1733712 DOI: 10.1210/Endo.130.2.1733712  0.412
1989 Freake HC, Schwartz HL, Oppenheimer JH. The regulation of lipogenesis by thyroid hormone and its contribution to thermogenesis Endocrinology. 125: 2868-2874. PMID 2583043 DOI: 10.1210/Endo-125-6-2868  0.422
1987 Cronrath CM, Freake HC, Mariash CN, Oppenheimer JH. Effect of thyroid hormones and high carbohydrate feeding on gene expression in rat epididymal adipose tissue Endocrinology. 120: 43-48. PMID 3780569  0.302
1987 Freake HC, Oppenheimer JH. Stimulation and S14 mRNAand lipogenesis in brown fat by hypothyroidism, cold exposure, and cafeteria feeding: Evidence supporting a general role for S14 in lipogenesis and lipogenesis in the maintenance of thermogenesis Proceedings of the National Academy of Sciences of the United States of America. 84: 3070-3074. PMID 3472252  0.301
1986 CRONRATH CM, FREAKE H, OPPENHEIMER JH. Effect of thyroid hormones and carbohydrate diet on mRNA activity profiles in rat adipose tissue Acta Endocrinologica. 113: S115. DOI: 10.1530/acta.0.111S115  0.32
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