Stephen W. Scheff, PhD - Publications

Affiliations: 
University of Kentucky, Lexington, KY 

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Bradley-Whitman MA, Roberts KN, Abner EL, Scheff SW, Lynn BC, Lovell MA. A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury. Brain Injury. 1-18. PMID 29283288 DOI: 10.1080/02699052.2017.1418907  0.426
2016 Scheff S, Ansari M. Natural compounds as a therapeutic intervention following traumatic brain injury: the role of phytochemicals. Journal of Neurotrauma. PMID 27846772 DOI: 10.1089/neu.2016.4718  0.314
2016 Scheff SW, Roberts KN. Cognitive assessment of Pycnogenol therapy following traumatic brain injury. Neuroscience Letters. PMID 27737807 DOI: 10.1016/J.Neulet.2016.10.016  0.482
2016 Mufson EJ, Ikonomovic MD, Counts SE, Perez SE, Malek-Ahmadi M, Scheff SW, Ginsberg SD. Molecular and Cellular Pathophysiology of Preclinical Alzheimer's Disease. Behavioural Brain Research. PMID 27185734 DOI: 10.1016/J.Bbr.2016.05.030  0.319
2016 Scheff SW, Ansari MA, Mufson EJ. Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology. Neurobiology of Aging. 42: 1-12. PMID 27143416 DOI: 10.1016/J.Neurobiolaging.2016.02.030  0.322
2016 Furman JL, Sompol P, Kraner SD, Pleiss MM, Putman EJ, Dunkerson J, Mohmmad Abdul H, Roberts KN, Scheff SW, Norris CM. Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1502-15. PMID 26843634 DOI: 10.1523/Jneurosci.1930-15.2016  0.486
2015 Norris CM, Sompol P, Roberts KN, Ansari M, Scheff SW. Pycnogenol protects CA3-CA1 synaptic function in a rat model of traumatic brain injury. Experimental Neurology. PMID 26607913 DOI: 10.1016/J.Expneurol.2015.11.006  0.434
2015 Margulies SS, Anderson GD, Atif F, Badaut J, Clark RS, Empey P, Guseva M, Hoane MR, Huh JW, Pauly JR, Raghupathi R, Scheff S, Stein D, Tang H, Hicks M. Combination Therapies for Traumatic Brain Injury: Retrospective Considerations. Journal of Neurotrauma. PMID 25970337 DOI: 10.1089/neu.2014.3855  0.304
2015 Mufson EJ, Mahady L, Waters D, Counts SE, Perez SE, DeKosky ST, Ginsberg SD, Ikonomovic MD, Scheff SW, Binder LI. Hippocampal plasticity during the progression of Alzheimer's disease. Neuroscience. PMID 25772787 DOI: 10.1016/J.Neuroscience.2015.03.006  0.335
2015 Scheff SW, Price DA, Ansari MA, Roberts KN, Schmitt FA, Ikonomovic MD, Mufson EJ. Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 43: 1073-90. PMID 25147118 DOI: 10.3233/Jad-141518  0.37
2014 Ansari MA, Roberts KN, Scheff SW. A time course of NADPH-oxidase up-regulation and endothelial nitric oxide synthase activation in the hippocampus following neurotrauma. Free Radical Biology & Medicine. 77: 21-9. PMID 25224032 DOI: 10.1016/J.Freeradbiomed.2014.08.025  0.333
2014 Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, ... ... Scheff SW, et al. Development of a database for translational spinal cord injury research. Journal of Neurotrauma. 31: 1789-99. PMID 25077610 DOI: 10.1089/Neu.2014.3399  0.305
2014 Neuman KM, Molina-Campos E, Musial TF, Price AL, Oh KJ, Wolke ML, Buss EW, Scheff SW, Mufson EJ, Nicholson DA. Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons. Brain Structure & Function. PMID 25031178 DOI: 10.1007/S00429-014-0848-Z  0.362
2014 Matveev SV, Spielmann HP, Metts BM, Chen J, Onono F, Zhu H, Scheff SW, Walker LC, LeVine H. A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain. Journal of Neurochemistry. 131: 356-68. PMID 24995708 DOI: 10.1111/Jnc.12815  0.309
2014 Abisambra JF, Scheff S. Brain injury in the context of tauopathies. Journal of Alzheimer's Disease : Jad. 40: 495-518. PMID 24496078 DOI: 10.3233/Jad-131019  0.433
2014 Scheff SW, Neltner JH, Nelson PT. Is synaptic loss a unique hallmark of Alzheimer's disease? Biochemical Pharmacology. 88: 517-28. PMID 24412275 DOI: 10.1016/J.Bcp.2013.12.028  0.366
2013 Nelson PT, Smith CD, Abner EL, Wilfred BJ, Wang WX, Neltner JH, Baker M, Fardo DW, Kryscio RJ, Scheff SW, Jicha GA, Jellinger KA, Van Eldik LJ, Schmitt FA. Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease. Acta Neuropathologica. 126: 161-77. PMID 23864344 DOI: 10.1007/S00401-013-1154-1  0.331
2013 Ansari MA, Roberts KN, Scheff SW. Dose- and time-dependent neuroprotective effects of Pycnogenol following traumatic brain injury. Journal of Neurotrauma. 30: 1542-9. PMID 23557184 DOI: 10.1089/Neu.2013.2910  0.493
2013 Scheff SW, Price DA, Schmitt FA, Roberts KN, Ikonomovic MD, Mufson EJ. Synapse stability in the precuneus early in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 35: 599-609. PMID 23478309 DOI: 10.3233/Jad-122353  0.358
2013 Scheff SW, Ansari MA, Roberts KN. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Experimental Neurology. 239: 183-91. PMID 23059456 DOI: 10.1016/J.Expneurol.2012.09.019  0.48
2012 Mufson EJ, He B, Nadeem M, Perez SE, Counts SE, Leurgans S, Fritz J, Lah J, Ginsberg SD, Wuu J, Scheff SW. Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 1018-29. PMID 23095849 DOI: 10.1097/Nen.0B013E318272Caab  0.314
2012 Sama DM, Mohmmad Abdul H, Furman JL, Artiushin IA, Szymkowski DE, Scheff SW, Norris CM. Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats. Plos One. 7: e38170. PMID 22666474 DOI: 10.1371/Journal.Pone.0038170  0.352
2012 Hussain ZM, Fitting S, Watanabe H, Usynin I, Yakovleva T, Knapp PE, Scheff SW, Hauser KF, Bakalkin G. Lateralized response of dynorphin a peptide levels after traumatic brain injury. Journal of Neurotrauma. 29: 1785-93. PMID 22468884 DOI: 10.1089/Neu.2011.2286  0.455
2012 Counts SE, He B, Nadeem M, Wuu J, Scheff SW, Mufson EJ. Hippocampal drebrin loss in mild cognitive impairment. Neuro-Degenerative Diseases. 10: 216-9. PMID 22310934 DOI: 10.1159/000333122  0.351
2012 Mufson EJ, Binder L, Counts SE, DeKosky ST, de Toledo-Morrell L, Ginsberg SD, Ikonomovic MD, Perez SE, Scheff SW. Mild cognitive impairment: pathology and mechanisms. Acta Neuropathologica. 123: 13-30. PMID 22101321 DOI: 10.1007/S00401-011-0884-1  0.304
2012 Hunt RF, Haselhorst LA, Schoch KM, Bach EC, Rios-Pilier J, Scheff SW, Saatman KE, Smith BN. Posttraumatic mossy fiber sprouting is related to the degree of cortical damage in three mouse strains. Epilepsy Research. 99: 167-70. PMID 22047981 DOI: 10.1016/J.Eplepsyres.2011.10.011  0.597
2011 Ikonomovic MD, Klunk WE, Abrahamson EE, Wuu J, Mathis CA, Scheff SW, Mufson EJ, DeKosky ST. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease. Neurology. 77: 39-47. PMID 21700583 DOI: 10.1212/Wnl.0B013E3182231419  0.313
2011 Saijo E, Scheff SW, Telling GC. Unaltered prion protein expression in Alzheimer disease patients. Prion. 5: 109-16. PMID 21654203 DOI: 10.4161/Pri.5.2.16355  0.308
2011 Hunt RF, Scheff SW, Smith BN. Synaptic reorganization of inhibitory hilar interneuron circuitry after traumatic brain injury in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6880-90. PMID 21543618 DOI: 10.1523/Jneurosci.0032-11.2011  0.628
2011 Nelson PT, Head E, Schmitt FA, Davis PR, Neltner JH, Jicha GA, Abner EL, Smith CD, Van Eldik LJ, Kryscio RJ, Scheff SW. Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies. Acta Neuropathologica. 121: 571-87. PMID 21516511 DOI: 10.1007/S00401-011-0826-Y  0.326
2011 Ansari MA, Scheff SW. NADPH-oxidase activation and cognition in Alzheimer disease progression. Free Radical Biology & Medicine. 51: 171-8. PMID 21457777 DOI: 10.1016/J.Freeradbiomed.2011.03.025  0.319
2011 Pleasant JM, Carlson SW, Mao H, Scheff SW, Yang KH, Saatman KE. Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studies. Journal of Neurotrauma. 28: 2245-62. PMID 21341976 DOI: 10.1089/Neu.2010.1499  0.464
2011 Scheff SW, Price DA, Schmitt FA, Scheff MA, Mufson EJ. Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 547-57. PMID 21297265 DOI: 10.3233/Jad-2011-101782  0.336
2011 Kelso ML, Scheff NN, Scheff SW, Pauly JR. Melatonin and minocycline for combinatorial therapy to improve functional and histopathological deficits following traumatic brain injury. Neuroscience Letters. 488: 60-4. PMID 21056621 DOI: 10.1016/J.Neulet.2010.11.003  0.466
2010 Fee DB, Swartz KR, Scheff N, Roberts K, Gabbita P, Scheff S. Melatonin-analog, β-methyl-6-chloromelatonin, supplementation in spinal cord injury Brain Research. 1340: 81-85. PMID 20420812 DOI: 10.1016/J.Brainres.2010.04.047  0.328
2010 Gilmer LK, Ansari MA, Roberts KN, Scheff SW. Age-related mitochondrial changes after traumatic brain injury. Journal of Neurotrauma. 27: 939-50. PMID 20175672 DOI: 10.1089/Neu.2009.1181  0.458
2010 Hunt RF, Scheff SW, Smith BN. Regionally localized recurrent excitation in the dentate gyrus of a cortical contusion model of posttraumatic epilepsy. Journal of Neurophysiology. 103: 1490-500. PMID 20089815 DOI: 10.1152/Jn.00957.2009  0.634
2010 Ansari MA, Scheff SW. Oxidative stress in the progression of Alzheimer disease in the frontal cortex. Journal of Neuropathology and Experimental Neurology. 69: 155-67. PMID 20084018 DOI: 10.1097/Nen.0B013E3181Cb5Af4  0.312
2010 Gilmer LK, Ansari MA, Roberts KN, Scheff SW. Age-related changes in mitochondrial respiration and oxidative damage in the cerebral cortex of the Fischer 344 rat. Mechanisms of Ageing and Development. 131: 133-43. PMID 20080122 DOI: 10.1016/J.Mad.2009.12.011  0.336
2010 Scheff SW, Price DA, Ansari MA, Murphy P, Mufson EJ. P1-468: How Do Synaptic Numers and Synaptic Proteins Correlate With Ab42 in Association Neocortex in the Progression of Alzheimer's Disease? Alzheimer's & Dementia. 6: e4-e4. DOI: 10.1016/J.Jalz.2010.08.013  0.308
2009 Kelso ML, Scheff SW, Pauly JR, Loftin CD. Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. Bmc Neuroscience. 10: 108. PMID 19719848 DOI: 10.1186/1471-2202-10-108  0.407
2009 Gilmer LK, Roberts KN, Joy K, Sullivan PG, Scheff SW. Early mitochondrial dysfunction after cortical contusion injury. Journal of Neurotrauma. 26: 1271-80. PMID 19637966 DOI: 10.1089/Neu.2008-0857  0.617
2009 Norris CM, Scheff SW. Recovery of afferent function and synaptic strength in hippocampal CA1 following traumatic brain injury. Journal of Neurotrauma. 26: 2269-78. PMID 19604098 DOI: 10.1089/Neu.2009.1029  0.436
2009 Hunt RF, Scheff SW, Smith BN. Posttraumatic epilepsy after controlled cortical impact injury in mice. Experimental Neurology. 215: 243-52. PMID 19013458 DOI: 10.1016/J.Expneurol.2008.10.005  0.621
2009 Nelson PT, Abner EL, Scheff SW, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Patel E, Markesbery WR. Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment. Neuroscience Letters. 450: 336-9. PMID 19010392 DOI: 10.1016/J.Neulet.2008.11.006  0.355
2008 Pettigrew LC, Kindy MS, Scheff S, Springer JE, Kryscio RJ, Li Y, Grass DS. Focal cerebral ischemia in the TNFalpha-transgenic rat. Journal of Neuroinflammation. 5: 47. PMID 18947406 DOI: 10.1186/1742-2094-5-47  0.389
2008 Anderson KJ, Scheff SW, Miller KM, Roberts KN, Gilmer LK, Yang C, Shaw G. The phosphorylated axonal form of the neurofilament subunit NF-H (pNF-H) as a blood biomarker of traumatic brain injury. Journal of Neurotrauma. 25: 1079-85. PMID 18729720 DOI: 10.1089/Neu.2007.0488  0.425
2008 Guseva MV, Hopkins DM, Scheff SW, Pauly JR. Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury. Journal of Neurotrauma. 25: 975-83. PMID 18665805 DOI: 10.1089/Neu.2008.0516  0.465
2008 Ansari MA, Roberts KN, Scheff SW. A time course of contusion-induced oxidative stress and synaptic proteins in cortex in a rat model of TBI. Journal of Neurotrauma. 25: 513-26. PMID 18533843 DOI: 10.1089/Neu.2007.0451  0.379
2008 Ansari MA, Roberts KN, Scheff SW. Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury. Free Radical Biology & Medicine. 45: 443-52. PMID 18501200 DOI: 10.1016/J.Freeradbiomed.2008.04.038  0.382
2008 Gilmer LK, Roberts KN, Scheff SW. Efficacy of progesterone following a moderate unilateral cortical contusion injury. Journal of Neurotrauma. 25: 593-602. PMID 18476780 DOI: 10.1089/Neu.2007.0477  0.451
2008 Scheff SW, Price DA, Schmitt FA, Mufson EJ. P4-158: Preservation of synaptic numbers in the precuneus associated with mild cognitive impairment and mild-to-moderate Alzheimer's disease Alzheimer's & Dementia. 4: T716-T717. DOI: 10.1016/J.Jalz.2008.05.2225  0.311
2007 Onifer SM, Rabchevsky AG, Scheff SW. Rat models of traumatic spinal cord injury to assess motor recovery. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 48: 385-95. PMID 17712224 DOI: 10.1093/Ilar.48.4.385  0.412
2007 Adjan VV, Hauser KF, Bakalkin G, Yakovleva T, Gharibyan A, Scheff SW, Knapp PE. Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons. Neuroscience. 148: 724-36. PMID 17698296 DOI: 10.1016/J.Neuroscience.2007.05.053  0.413
2007 Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology. 68: 1501-8. PMID 17470753 DOI: 10.1212/01.Wnl.0000260698.46517.8F  0.327
2007 Swartz KR, Fee DB, Joy KM, Roberts KN, Sun S, Scheff NN, Wilson ME, Scheff SW. Gender differences in spinal cord injury are not estrogen-dependent. Journal of Neurotrauma. 24: 473-80. PMID 17402853 DOI: 10.1089/Neu.2006.0167  0.34
2007 Rabchevsky AG, Sullivan PG, Scheff SW. Temporal-spatial dynamics in oligodendrocyte and glial progenitor cell numbers throughout ventrolateral white matter following contusion spinal cord injury. Glia. 55: 831-43. PMID 17390308 DOI: 10.1002/Glia.20508  0.557
2007 Bruce-Keller AJ, Dimayuga FO, Reed JL, Wang C, Angers R, Wilson ME, Dimayuga VM, Scheff SW. Gender and estrogen manipulation do not affect traumatic brain injury in mice. Journal of Neurotrauma. 24: 203-15. PMID 17263684 DOI: 10.1089/Neu.2006.0163  0.417
2007 Fee DB, Swartz KR, Joy KM, Roberts KN, Scheff NN, Scheff SW. Effects of progesterone on experimental spinal cord injury. Brain Research. 1137: 146-52. PMID 17204255 DOI: 10.1016/J.Brainres.2006.12.024  0.391
2006 Scheff SW, Price DA. Alzheimer's disease-related alterations in synaptic density: neocortex and hippocampus. Journal of Alzheimer's Disease : Jad. 9: 101-15. PMID 16914849 DOI: 10.3233/Jad-2006-9S312  0.385
2006 Shao C, Roberts KN, Markesbery WR, Scheff SW, Lovell MA. Oxidative stress in head trauma in aging. Free Radical Biology & Medicine. 41: 77-85. PMID 16781455 DOI: 10.1016/J.Freeradbiomed.2006.03.007  0.421
2006 Kelso ML, Wehner JM, Collins AC, Scheff SW, Pauly JR. The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice. Brain Research. 1083: 204-10. PMID 16545784 DOI: 10.1016/J.Brainres.2006.01.127  0.404
2006 Scheff SW, Price DA, Schmitt FA, Mufson EJ. Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment. Neurobiology of Aging. 27: 1372-84. PMID 16289476 DOI: 10.1016/J.Neurobiolaging.2005.09.012  0.352
2006 Scheff SW, Price DA, Schmitt FA, Schneider JA, Bennett DA, DeKosky ST, Mufson EJ. O1-01-01: Synaptic alterations in inferior temporal lobe in Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) Alzheimer's & Dementia. 2: S7-S8. DOI: 10.1016/J.Jalz.2006.05.034  0.313
2005 Shaw G, Yang C, Ellis R, Anderson K, Parker Mickle J, Scheff S, Pike B, Anderson DK, Howland DR. Hyperphosphorylated neurofilament NF-H is a serum biomarker of axonal injury. Biochemical and Biophysical Research Communications. 336: 1268-77. PMID 16176808 DOI: 10.1016/J.Bbrc.2005.08.252  0.378
2005 Scheff SW, Price DA, Hicks RR, Baldwin SA, Robinson S, Brackney C. Synaptogenesis in the hippocampal CA1 field following traumatic brain injury. Journal of Neurotrauma. 22: 719-32. PMID 16004576 DOI: 10.1089/Neu.2005.22.719  0.488
2005 Keller JN, Schmitt FA, Scheff SW, Ding Q, Chen Q, Butterfield DA, Markesbery WR. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology. 64: 1152-6. PMID 15824339 DOI: 10.1212/01.Wnl.0000156156.13641.Ba  0.335
2005 Anderson KJ, Miller KM, Fugaccia I, Scheff SW. Regional distribution of fluoro-jade B staining in the hippocampus following traumatic brain injury. Experimental Neurology. 193: 125-30. PMID 15817271 DOI: 10.1016/J.Expneurol.2004.11.025  0.442
2005 Hall ED, Sullivan PG, Gibson TR, Pavel KM, Thompson BM, Scheff SW. Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: more than a focal brain injury. Journal of Neurotrauma. 22: 252-65. PMID 15716631 DOI: 10.1089/Neu.2005.22.252  0.609
2005 Ravikumar R, Fugaccia I, Scheff SW, Geddes JW, Srinivasan C, Toborek M. Nicotine attenuates morphological deficits in a contusion model of spinal cord injury. Journal of Neurotrauma. 22: 240-51. PMID 15716630 DOI: 10.1089/Neu.2005.22.240  0.388
2005 Gabbita SP, Scheff SW, Menard RM, Roberts K, Fugaccia I, Zemlan FP. Cleaved-tau: a biomarker of neuronal damage after traumatic brain injury. Journal of Neurotrauma. 22: 83-94. PMID 15665604 DOI: 10.1089/Neu.2005.22.83  0.43
2005 Hauser KF, Aldrich JV, Anderson KJ, Bakalkin G, Christie MJ, Hall ED, Knapp PE, Scheff SW, Singh IN, Vissel B, Woods AS, Yakovleva T, Shippenberg TS. Pathobiology of dynorphins in trauma and disease. Frontiers in Bioscience : a Journal and Virtual Library. 10: 216-35. PMID 15574363 DOI: 10.2741/1522  0.3
2004 Sullivan PG, Springer JE, Hall ED, Scheff SW. Mitochondrial uncoupling as a therapeutic target following neuronal injury. Journal of Bioenergetics and Biomembranes. 36: 353-6. PMID 15377871 DOI: 10.1023/B:Jobb.0000041767.30992.19  0.552
2004 Sullivan PG, Rabchevsky AG, Keller JN, Lovell M, Sodhi A, Hart RP, Scheff SW. Intrinsic differences in brain and spinal cord mitochondria: Implication for therapeutic interventions. The Journal of Comparative Neurology. 474: 524-34. PMID 15174070 DOI: 10.1002/Cne.20130  0.528
2004 Scheff SW, Dhillon HS. Creatine-enhanced diet alters levels of lactate and free fatty acids after experimental brain injury. Neurochemical Research. 29: 469-79. PMID 15002746 DOI: 10.1023/B:Nere.0000013753.22615.59  0.42
2004 Scheff SW, Price DA, Schmitt FA, Cochran EJ, Bennett DA, Mufson EJ. P3-170 Stereological assessment of hippocampal synapses in people with Alzheimer's disease and mild cognitive impairment Neurobiology of Aging. 25: S404. DOI: 10.1016/S0197-4580(04)81322-8  0.31
2003 Anderson KJ, Fugaccia I, Scheff SW. Fluoro-jade B stains quiescent and reactive astrocytes in the rodent spinal cord. Journal of Neurotrauma. 20: 1223-31. PMID 14651809 DOI: 10.1089/089771503770802899  0.371
2003 Scheff SW, Price DA. Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. Neurobiology of Aging. 24: 1029-46. PMID 14643375 DOI: 10.1016/J.Neurobiolaging.2003.08.002  0.352
2003 Scheff S. Reactive Synaptogenesis in Aging and Alzheimer's Disease: Lessons Learned in the Cotman Laboratory Neurochemical Research. 28: 1625-1630. PMID 14584816 DOI: 10.1023/A:1026048619220  0.358
2003 Rabchevsky AG, Sullivan PG, Fugaccia I, Scheff SW. Creatine diet supplement for spinal cord injury: influences on functional recovery and tissue sparing in rats. Journal of Neurotrauma. 20: 659-69. PMID 12908927 DOI: 10.1089/089771503322144572  0.547
2003 Verbois SL, Hopkins DM, Scheff SW, Pauly JR. Chronic intermittent nicotine administration attenuates traumatic brain injury-induced cognitive dysfunction. Neuroscience. 119: 1199-208. PMID 12831873 DOI: 10.1016/S0306-4522(03)00206-9  0.426
2003 Scheff SW, Rabchevsky AG, Fugaccia I, Main JA, Lumpp JE. Experimental modeling of spinal cord injury: characterization of a force-defined injury device. Journal of Neurotrauma. 20: 179-93. PMID 12675971 DOI: 10.1089/08977150360547099  0.42
2003 Verbois SL, Scheff SW, Pauly JR. Chronic nicotine treatment attenuates alpha 7 nicotinic receptor deficits following traumatic brain injury. Neuropharmacology. 44: 224-33. PMID 12623221 DOI: 10.1016/S0028-3908(02)00366-0  0.421
2002 Verbois SL, Scheff SW, Pauly JR. Time-dependent changes in rat brain cholinergic receptor expression after experimental brain injury. Journal of Neurotrauma. 19: 1569-85. PMID 12542858 DOI: 10.1089/089771502762300238  0.42
2002 Scheff SW, Saucier DA, Cain ME. A statistical method for analyzing rating scale data: the BBB locomotor score. Journal of Neurotrauma. 19: 1251-60. PMID 12427332 DOI: 10.1089/08977150260338038  0.321
2002 Sullivan PG, Keller JN, Bussen WL, Scheff SW. Cytochrome c release and caspase activation after traumatic brain injury. Brain Research. 949: 88-96. PMID 12213303 DOI: 10.1016/S0006-8993(02)02968-2  0.594
2002 McCullers DL, Sullivan PG, Scheff SW, Herman JP. Traumatic brain injury regulates adrenocorticosteroid receptor mRNA levels in rat hippocampus. Brain Research. 947: 41-9. PMID 12144851 DOI: 10.1016/S0006-8993(02)02904-9  0.6
2002 Rabchevsky AG, Fugaccia I, Sullivan PG, Blades DA, Scheff SW. Efficacy of methylprednisolone therapy for the injured rat spinal cord. Journal of Neuroscience Research. 68: 7-18. PMID 11933044 DOI: 10.1002/Jnr.10187  0.563
2002 Thompson JS, Brown SA, Khurdayan V, Zeynalzadedan A, Sullivan PG, Scheff SW. Early effects of tribromoethanol, ketamine/xylazine, pentobarbitol, and isoflurane anesthesia on hepatic and lymphoid tissue in ICR mice. Comparative Medicine. 52: 63-7. PMID 11900415  0.43
2002 McCullers DL, Sullivan PG, Scheff SW, Herman JP. Mifepristone protects CA1 hippocampal neurons following traumatic brain injury in rat. Neuroscience. 109: 219-30. PMID 11801359 DOI: 10.1016/S0306-4522(01)00477-8  0.581
2001 Scheff SW, Price DA. Alzheimer's disease-related synapse loss in the cingulate cortex. Journal of Alzheimer's Disease : Jad. 3: 495-505. PMID 12214036 DOI: 10.3233/Jad-2001-3509  0.339
2001 Prasad RM, Doubinskaia I, Singh DK, Campbell G, Mace D, Fletcher A, Dendle P, Yurek DM, Scheff SW, Kraemer PJ. Effects of binge ethanol administration on the behavioral outcome of rats after lateral fluid percussion brain injury. Journal of Neurotrauma. 18: 1019-29. PMID 11686489 DOI: 10.1089/08977150152693719  0.332
2001 Rabchevsky AG, Fugaccia I, Sullivan PG, Scheff SW. Cyclosporin A treatment following spinal cord injury to the rat: behavioral effects and stereological assessment of tissue sparing. Journal of Neurotrauma. 18: 513-22. PMID 11393254 DOI: 10.1089/089771501300227314  0.577
2001 Scheff SW, Price DA, Sparks DL. Quantitative assessment of possible age-related change in synaptic numbers in the human frontal cortex. Neurobiology of Aging. 22: 355-65. PMID 11378240 DOI: 10.1016/S0197-4580(01)00222-6  0.364
2001 Poloyac SM, Perez A, Scheff S, Blouin RA. Tissue-specific alterations in the 6-hydroxylation of chlorzoxazone following traumatic brain injury in the rat Drug Metabolism and Disposition. 29: 296-298. PMID 11181498  0.33
2000 Verbois SL, Sullivan PG, Scheff SW, Pauly JR. Traumatic brain injury reduces hippocampal alpha7 nicotinic cholinergic receptor binding. Journal of Neurotrauma. 17: 1001-11. PMID 11101204 DOI: 10.1089/Neu.2000.17.1001  0.545
2000 Zhang P, Abraham VS, Kraft KR, Rabchevsky AG, Scheff SW, Swain JA. Hyperthermic preconditioning protects against spinal cord ischemic injury. The Annals of Thoracic Surgery. 70: 1490-5. PMID 11093475 DOI: 10.1016/S0003-4975(00)01851-8  0.344
2000 Sullivan PG, Geiger JD, Mattson MP, Scheff SW. Dietary supplement creatine protects against traumatic brain injury. Annals of Neurology. 48: 723-9. PMID 11079535 DOI: 10.1002/1531-8249(200011)48:5<723::Aid-Ana5>3.0.Co;2-W  0.587
2000 Sullivan PG, Rabchevsky AG, Hicks RR, Gibson TR, Fletcher-Turner A, Scheff SW. Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats. Neuroscience. 101: 289-95. PMID 11074152 DOI: 10.1016/S0306-4522(00)00380-8  0.612
2000 Rabchevsky AG, Fugaccia I, Turner AF, Blades DA, Mattson MP, Scheff SW. Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat. Experimental Neurology. 164: 280-91. PMID 10915567 DOI: 10.1006/Exnr.2000.7399  0.398
2000 Albensi BC, Sullivan PG, Thompson MB, Scheff SW, Mattson MP. Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity. Experimental Neurology. 162: 385-9. PMID 10739643 DOI: 10.1006/Exnr.1999.7338  0.592
2000 Sullivan PG, Thompson M, Scheff SW. Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury. Experimental Neurology. 161: 631-7. PMID 10686082 DOI: 10.1006/Exnr.1999.7282  0.618
1999 Sullivan PG, Thompson MB, Scheff SW. Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury. Experimental Neurology. 160: 226-34. PMID 10630207 DOI: 10.1006/Exnr.1999.7197  0.574
1999 Rabchevsky AG, Fugaccia I, Fletcher-Turner A, Blades DA, Mattson MP, Scheff SW. Basic fibroblast growth factor (bFGF) enhances tissue sparing and functional recovery following moderate spinal cord injury. Journal of Neurotrauma. 16: 817-30. PMID 10521141 DOI: 10.1089/Neu.1999.16.817  0.376
1999 Scheff SW, Sullivan PG. Cyclosporin A significantly ameliorates cortical damage following experimental traumatic brain injury in rodents. Journal of Neurotrauma. 16: 783-92. PMID 10521138 DOI: 10.1089/Neu.1999.16.783  0.618
1999 Gewirtz RJ, Dhillon HS, Goes SE, DeAtley SM, Scheff SW. Lactate and free fatty acids after subarachnoid hemorrhage. Brain Research. 840: 84-91. PMID 10517955 DOI: 10.1016/S0006-8993(99)01752-7  0.331
1999 Sullivan PG, Bruce-Keller AJ, Rabchevsky AG, Christakos S, Clair DK, Mattson MP, Scheff SW. Exacerbation of damage and altered NF-kappaB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6248-56. PMID 10414954  0.51
1999 Dhillon HS, Carman HM, Zhang D, Scheff SW, Prasad MR. Severity of experimental brain injury on lactate and free fatty acid accumulation and Evans blue extravasation in the rat cortex and hippocampus. Journal of Neurotrauma. 16: 455-69. PMID 10391363 DOI: 10.1089/Neu.1999.16.455  0.465
1999 Sullivan PG, Bruce-Keller AJ, Rabchevsky AG, Christakos S, Clair DKS, Mattson MP, Scheff SW. Exacerbation of Damage and Altered NF-κB Activation in Mice Lacking Tumor Necrosis Factor Receptors after Traumatic Brain Injury The Journal of Neuroscience. 19: 6248-6256. DOI: 10.1523/Jneurosci.19-15-06248.1999  0.561
1998 Baldwin SA, Broderick R, Blades DA, Scheff SW. Alterations in temporal/spatial distribution of GFAP- and vimentin-positive astrocytes after spinal cord contusion with the New York University spinal cord injury device. Journal of Neurotrauma. 15: 1015-26. PMID 9872458 DOI: 10.1089/Neu.1998.15.1015  0.406
1998 Scheff SW, Price DA. Synaptic density in the inner molecular layer of the hippocampal dentate gyrus in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 57: 1146-53. PMID 9862637 DOI: 10.1097/00005072-199812000-00006  0.352
1998 Sullivan PG, Keller JN, Mattson MP, Scheff SW. Traumatic brain injury alters synaptic homeostasis: implications for impaired mitochondrial and transport function. Journal of Neurotrauma. 15: 789-98. PMID 9814635 DOI: 10.1089/Neu.1998.15.789  0.594
1998 Baldwin SA, Broderick R, Osbourne D, Waeg G, Blades DA, Scheff SW. The presence of 4-hydroxynonenal/protein complex as an indicator of oxidative stress after experimental spinal cord contusion in a rat model. Journal of Neurosurgery. 88: 874-83. PMID 9576257 DOI: 10.3171/Jns.1998.88.5.0874  0.369
1997 Hicks RR, Baldwin SA, Scheff SW. Serum extravasation and cytoskeletal alterations following traumatic brain injury in rats. Comparison of lateral fluid percussion and cortical impact models. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 32: 1-16. PMID 9437655 DOI: 10.1007/Bf02815164  0.476
1997 Hinkle DA, Baldwin SA, Scheff SW, Wise PM. GFAP and S100beta expression in the cortex and hippocampus in response to mild cortical contusion. Journal of Neurotrauma. 14: 729-38. PMID 9383091 DOI: 10.1089/Neu.1997.14.729  0.391
1997 Scheff SW, Baldwin SA, Brown RW, Kraemer PJ. Morris water maze deficits in rats following traumatic brain injury: lateral controlled cortical impact. Journal of Neurotrauma. 14: 615-27. PMID 9337124 DOI: 10.1089/Neu.1997.14.615  0.471
1997 Dhillon HS, Dose JM, Scheff SW, Prasad MR. Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage. Experimental Neurology. 146: 240-9. PMID 9225757 DOI: 10.1006/Exnr.1997.6524  0.47
1997 Baldwin SA, Gibson T, Callihan CT, Sullivan PG, Palmer E, Scheff SW. Neuronal cell loss in the CA3 subfield of the hippocampus following cortical contusion utilizing the optical disector method for cell counting. Journal of Neurotrauma. 14: 385-98. PMID 9219853 DOI: 10.1089/Neu.1997.14.385  0.534
1997 Runge VM, Wells JW, Baldwin SA, Scheff SW, Blades DA. Evaluation of the temporal evolution of acute spinal cord injury. Investigative Radiology. 32: 105-10. PMID 9039583 DOI: 10.1097/00004424-199702000-00006  0.394
1997 Baldwin SA, Scheff SW. Alterations in glial fibrillary acidic protein and vimentin in hippocampal astrocytes following entorhinal cortex lesion Neuroscience Research Communications. 20: 157-165. DOI: 10.1002/(Sici)1520-6769(199705)20:3<157::Aid-Nrc197>3.0.Co;2-7  0.308
1996 DeKosky ST, Scheff SW, Styren SD. Structural correlates of cognition in dementia: quantification and assessment of synapse change. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 417-21. PMID 9117556 DOI: 10.1006/Neur.1996.0056  0.317
1996 Kraemer PJ, Brown RW, Baldwin SA, Scheff SW. Validation of a single-day Morris Water Maze procedure used to assess cognitive deficits associated with brain damage. Brain Research Bulletin. 39: 17-22. PMID 8846103 DOI: 10.1016/0361-9230(95)02028-4  0.32
1996 Baldwin SA, Scheff SW. Intermediate filament change in astrocytes following mild cortical contusion. Glia. 16: 266-75. PMID 8833197 DOI: 10.1002/(Sici)1098-1136(199603)16:3<266::Aid-Glia9>3.0.Co;2-#  0.44
1996 Baldwin SA, Fugaccia I, Brown DR, Brown LV, Scheff SW. Blood-brain barrier breach following cortical contusion in the rat. Journal of Neurosurgery. 85: 476-81. PMID 8751635 DOI: 10.3171/Jns.1996.85.3.0476  0.434
1996 Carbary T, Dhillon HS, Scheff SW, Prasad RM. Immunohistochemistry of tyrosine and dopamine-β-hydroxylases after experimental brain injury in the rat Neuroscience Research Communications. 18: 79-85. DOI: 10.1002/(Sici)1520-6769(199603)18:2<79::Aid-Nrc143>3.0.Co;2-A  0.362
1995 Mattson MP, Cheng B, Baldwin SA, Smith-Swintosky VL, Keller J, Geddes JW, Scheff SW, Christakos S. Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response. Journal of Neuroscience Research. 42: 357-70. PMID 8583504 DOI: 10.1002/Jnr.490420310  0.382
1994 Mattson MP, Scheff SW. Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and implications for therapy. Journal of Neurotrauma. 11: 3-33. PMID 8201625 DOI: 10.1089/Neu.1994.11.3  0.441
1994 Prasad MR, Dhillon HS, Carbary T, Dempsey RJ, Scheff SW. Enhanced phosphodiestric breakdown of phosphatidylinositol bisphosphate after experimental brain injury. Journal of Neurochemistry. 63: 773-6. PMID 8035202 DOI: 10.1046/J.1471-4159.1994.63020773.X  0.465
1993 Sparks DL, Liu H, Scheff SW, Coyne CM, Hunsaker JC. Temporal sequence of plaque formation in the cerebral cortex of non-demented individuals. Journal of Neuropathology and Experimental Neurology. 52: 135-42. PMID 8440995 DOI: 10.1097/00005072-199303000-00006  0.301
1993 Scheff SW, Sparks L, Price DA. Quantitative assessment of synaptic density in the entorhinal cortex in Alzheimer's disease. Annals of Neurology. 34: 356-61. PMID 8363352 DOI: 10.1002/Ana.410340309  0.348
1992 Scott SA, DeKosky ST, Sparks DL, Knox CA, Scheff SW. Amygdala cell loss and atrophy in Alzheimer's disease. Annals of Neurology. 32: 555-63. PMID 1456740 DOI: 10.1002/Ana.410320412  0.326
1991 Scott SA, DeKosky ST, Scheff SW. Volumetric atrophy of the amygdala in Alzheimer's disease: quantitative serial reconstruction. Neurology. 41: 351-6. PMID 2006000 DOI: 10.1212/Wnl.41.3.351  0.304
1991 Scheff SW, Scott SA, DeKosky ST. Quantitation of synaptic density in the septal nuclei of young and aged Fischer 344 rats. Neurobiology of Aging. 12: 3-12. PMID 2002880 DOI: 10.1016/0197-4580(91)90032-F  0.327
1990 DeKosky ST, Scheff SW. Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Annals of Neurology. 27: 457-64. PMID 2360787 DOI: 10.1002/Ana.410270502  0.361
1990 Scheff SW, DeKosky ST, Price DA. Quantitative assessment of cortical synaptic density in Alzheimer's disease. Neurobiology of Aging. 11: 29-37. PMID 2325814 DOI: 10.1016/0197-4580(90)90059-9  0.362
1990 Sparks DL, Hunsaker JC, Scheff SW, Kryscio RJ, Henson JL, Markesbery WR. Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease. Neurobiology of Aging. 11: 601-7. PMID 1704106 DOI: 10.1016/0197-4580(90)90024-T  0.32
1988 Scheff SW, Morse JK, DeKosky ST. Neurotrophic effects of steroids on lesion-induced growth in the hippocampus. I. The asteroidal condition. Brain Research. 457: 246-50. PMID 3219553 DOI: 10.1016/0006-8993(88)90692-0  0.303
1988 Doebler JA, Markesbery WR, Anthony A, Davies P, Scheff SW, Rhoads RE. Neuronal RNA in relation to Alz-50 immunoreactivity in Alzheimer's disease. Annals of Neurology. 23: 20-4. PMID 2449843 DOI: 10.1002/Ana.410230105  0.315
1986 Anderson KJ, Scheff SW, DeKosky ST. Reactive synaptogenesis in hippocampal area CA1 of aged and young adult rats. The Journal of Comparative Neurology. 252: 374-84. PMID 3793982 DOI: 10.1002/Cne.902520306  0.371
1986 Morse JK, Scheff SW, DeKosky ST. Gonadal steroids influence axon sprouting in the hippocampal dentate gyrus: a sexually dimorphic response. Experimental Neurology. 94: 649-58. PMID 3780911 DOI: 10.1016/0014-4886(86)90244-X  0.307
1986 Scheff SW, Hoff SF, Anderson KJ. Altered regulation of lesion-induced synaptogenesis by adrenalectomy and corticosterone in young adult rats. Experimental Neurology. 93: 456-70. PMID 3743694 DOI: 10.1016/0014-4886(86)90167-6  0.358
1985 DeKosky ST, Scheff SW, Hackney CG, Bass NH. Strain differences and laminar localization of structural neurochemical changes in aging rat. Neurobiology of Aging. 6: 277-86. PMID 4088423 DOI: 10.1016/0197-4580(85)90004-1  0.333
1985 DeKosky ST, Scheff SW, Markesbery WR. Laminar organization of cholinergic circuits in human frontal cortex in Alzheimer's disease and aging. Neurology. 35: 1425-31. PMID 4033925 DOI: 10.1212/Wnl.35.10.1425  0.339
1985 Scheff SW, Anderson KJ, DeKosky ST. Strain comparison of synaptic density in hippocampal CA1 of aged rats. Neurobiology of Aging. 6: 29-34. PMID 4000383 DOI: 10.1016/0197-4580(85)90068-5  0.323
1985 Vicedomini JP, Nonneman AJ, DeKosky ST, Scheff SW. Perinatal glucocorticoids alter dentate gyrus electrophysiology. Brain Research Bulletin. 15: 111-6. PMID 2994854 DOI: 10.1016/0361-9230(85)90126-1  0.332
1984 DeKosky ST, Scheff SW, Cotman CW. Elevated corticosterone levels. A possible cause of reduced axon sprouting in aged animals. Neuroendocrinology. 38: 33-8. PMID 6537997 DOI: 10.1159/000123862  0.346
1983 Scheff SW, DeKosky ST. Steroid suppression of axon sprouting in the hippocampal dentate gyrus of the adult rat: dose-response relationship. Experimental Neurology. 82: 183-91. PMID 6628607 DOI: 10.1016/0014-4886(83)90253-4  0.331
1982 DeKosky ST, Nonneman AJ, Scheff SW. Morphologic and behavioral effects of perinatal glucocorticoid administration. Physiology & Behavior. 29: 895-900. PMID 7156227 DOI: 10.1016/0031-9384(82)90340-7  0.335
1982 Scheff SW, Cotman CW. Chronic glucocorticoid therapy alters axon sprouting in the hippocampal dentate gyrus. Experimental Neurology. 76: 644-54. PMID 7084379 DOI: 10.1016/0014-4886(82)90131-5  0.378
1982 Hoff SF, Scheff SW, Cotman CW. Lesion-induced synaptogenesis in the dentate gyrus of aged rats: II. Demonstration of an impaired degeneration clearing response. The Journal of Comparative Neurology. 205: 253-9. PMID 7076896 DOI: 10.1002/Cne.902050305  0.33
1982 Hoff SF, Scheff SW, Benardo LS, Cotman CW. Lesion-induced synaptogenesis in the dentate gyrus of aged rats: I. Loss and reacquisition of normal synaptic density. The Journal of Comparative Neurology. 205: 246-52. PMID 7076895 DOI: 10.1002/Cne.902050304  0.343
1981 Hoff SF, Scheff SW, Kwan AY, Cotman CW. A new type of lesion-induced synaptogenesis: II. The effect of aging on synaptic turnover in non-denervated zones. Brain Research. 222: 15-27. PMID 7296261 DOI: 10.1016/0006-8993(81)90937-9  0.358
1981 Hoff SF, Scheff SW, Kwan AY, Cotman CW. A new type of lesion-induced synaptogenesis: I. Synaptic turnover in non-denervated zones of the dentate gyrus in young adult rats. Brain Research. 222: 1-13. PMID 7296257 DOI: 10.1016/0006-8993(81)90936-7  0.318
1980 Scheff SW, Benardo LS, Cotman CW. Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removal. Brain Research. 199: 21-38. PMID 7407623 DOI: 10.1016/0006-8993(80)90227-9  0.33
1979 Goldowitz D, Scheff SW, Cotman CW. The specificity of reactive synaptogenesis: a comparative study in the adult rat hippocampal formation. Brain Research. 170: 427-41. PMID 466422 DOI: 10.1016/0006-8993(79)90962-4  0.367
1979 Cotman CW, Scheff SW. Compensatory synapse growth in aged animals after neuronal death. Mechanisms of Ageing and Development. 9: 103-17. PMID 439948 DOI: 10.1016/0047-6374(79)90124-6  0.388
1978 Scheff SW, Benardo LS, Cotman CW. Lesion-induced vascular changes in the dentate gyrus following removal of the entorhinal cortex in adult rats. Experimental Neurology. 62: 815-20. PMID 750225 DOI: 10.1016/0014-4886(78)90288-1  0.314
1978 Scheff SW, Bernardo LS, Cotman CW. Decrease in adrenergic axon sprouting in the senescent rat. Science (New York, N.Y.). 202: 775-8. PMID 715443 DOI: 10.1126/Science.715443  0.334
1977 Scheff SW, Cotman CW. Recovery of spontaneous alternation following lesions of the entorhinal cortex in adult rats: possible correlation to axon sprouting. Behavioral Biology. 21: 286-93. PMID 911288 DOI: 10.1016/S0091-6773(77)90374-1  0.31
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