| Year |
Citation |
Score |
| 2007 |
Shankar N, Xia T, Kennedy SD, Krugh TR, Mathews DH, Turner DH. NMR reveals the absence of hydrogen bonding in adjacent UU and AG mismatches in an isolated internal loop from ribosomal RNA. Biochemistry. 46: 12665-78. PMID 17929882 DOI: 10.1021/Bi700802S |
0.416 |
|
| 2007 |
Chen G, Kierzek R, Yildirim I, Krugh TR, Turner DH, Kennedy SD. Stacking effects on local structure in RNA: changes in the structure of tandem GA pairs when flanking GC pairs are replaced by isoG-isoC pairs. The Journal of Physical Chemistry. B. 111: 6718-27. PMID 17411085 DOI: 10.1021/Jp068732M |
0.392 |
|
| 2007 |
Tolbert BS, Kennedy SD, Schroeder SJ, Krugh TR, Turner DH. NMR structures of (rGCUGAGGCU)2 and (rGCGGAUGCU)2: probing the structural features that shape the thermodynamic stability of GA pairs. Biochemistry. 46: 1511-22. PMID 17279616 DOI: 10.1021/Bi061350M |
0.419 |
|
| 2006 |
Shankar N, Kennedy SD, Chen G, Krugh TR, Turner DH. The NMR structure of an internal loop from 23S ribosomal RNA differs from its structure in crystals of 50s ribosomal subunits. Biochemistry. 45: 11776-89. PMID 17002278 DOI: 10.1021/Bi0605787 |
0.368 |
|
| 2006 |
Chen G, Kennedy SD, Qiao J, Krugh TR, Turner DH. An alternating sheared AA pair and elements of stability for a single sheared purine-purine pair flanked by sheared GA pairs in RNA. Biochemistry. 45: 6889-903. PMID 16734425 DOI: 10.1021/Bi0524464 |
0.546 |
|
| 2005 |
Chen G, Znosko BM, Kennedy SD, Krugh TR, Turner DH. Solution structure of an RNA internal loop with three consecutive sheared GA pairs. Biochemistry. 44: 2845-56. PMID 15723528 DOI: 10.1021/Bi048079Y |
0.415 |
|
| 2004 |
Znosko BM, Kennedy SD, Wille PC, Krugh TR, Turner DH. Structural features and thermodynamics of the J4/5 loop from the Candida albicans and Candida dubliniensis group I introns. Biochemistry. 43: 15822-37. PMID 15595837 DOI: 10.1021/Bi049256Y |
0.406 |
|
| 2003 |
Schroeder SJ, Fountain MA, Kennedy SD, Lukavsky PJ, Puglisi JD, Krugh TR, Turner DH. Thermodynamic stability and structural features of the J4/5 loop in a Pneumocystis carinii group I intron. Biochemistry. 42: 14184-96. PMID 14640686 DOI: 10.1021/Bi0301587 |
0.414 |
|
| 2003 |
Znosko BM, Barnes TW, Krugh TR, Turner DH. NMR studies of DNA single strands and DNA:RNA hybrids with and without 1-propynylation at C5 of oligopyrimidines. Journal of the American Chemical Society. 125: 6090-7. PMID 12785839 DOI: 10.1021/Ja021285D |
0.345 |
|
| 2002 |
Znosko BM, Burkard ME, Krugh TR, Turner DH. Molecular recognition in purine-rich internal loops: thermodynamic, structural, and dynamic consequences of purine for adenine substitutions in 5'(rGGCAAGCCU)2. Biochemistry. 41: 14978-87. PMID 12475247 DOI: 10.1021/Bi0203278 |
0.375 |
|
| 2002 |
Znosko BM, Burkard ME, Schroeder SJ, Krugh TR, Turner DH. Sheared Aanti.Aanti base pairs in a destabilizing 2 x 2 internal loop: the NMR structure of 5'(rGGCAAGCCU)2. Biochemistry. 41: 14969-77. PMID 12475246 DOI: 10.1021/Bi020326F |
0.41 |
|
| 2001 |
Zhang H, Fountain MA, Krugh TR. Structural characterization of a six-nucleotide RNA hairpin loop found in Escherichia coli, r(UUAAGU) Biochemistry. 40: 9879-9886. PMID 11502181 DOI: 10.1021/Bi011226X |
0.423 |
|
| 2000 |
Guckian KM, Krugh TR, Kool ET. Solution Structure of a Nonpolar, Non-Hydrogen-Bonded Base Pair Surrogate in DNA. Journal of the American Chemical Society. 122: 6841-6847. PMID 20882115 DOI: 10.1021/Ja994164V |
0.409 |
|
| 2000 |
Chen X, McDowell JA, Kierzek R, Krugh TR, Turner DH. Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G.U pairs: one hydrogen bond for each G.U pair in r(GGCGUGCC)(2) and two for each G.U pair in r(GAGUGCUC)(2). Biochemistry. 39: 8970-82. PMID 10913310 DOI: 10.1021/Bi992938E |
0.384 |
|
| 1998 |
Guckian KM, Krugh TR, Kool ET. Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair. Nature Structural Biology. 5: 954-9. PMID 9808039 DOI: 10.1038/2930 |
0.39 |
|
| 1996 |
Fountain MA, Serra MJ, Krugh TR, Turner DH. Structural features of a six-nucleotide RNA hairpin loop found in ribosomal RNA. Biochemistry. 35: 6539-48. PMID 8639602 DOI: 10.1021/Bi952697K |
0.385 |
|
| 1995 |
Fountain MA, Krugh TR. Structural characterization of a (+)-trans-anti-benzo[a]pyrene - DNA adduct using NMR, restrained energy minimization, and molecular dynamics Biochemistry. 34: 3152-3161. PMID 7880810 DOI: 10.1021/Bi00010A004 |
0.456 |
|
| 1994 |
Eckel LM, Krugh TR. Structural characterization of two interchangeable conformations of a 2-aminofluorene-modified DNA oligomer by NMR and energy minimization Biochemistry. 33: 13611-13624. PMID 7947770 DOI: 10.1021/Bi00250A012 |
0.414 |
|
| 1994 |
Eckel LM, Krugh TR. 2-aminofluorene modified dna duplex exists in two interchangeable conformations Nature Structural Biology. 1: 89-94. PMID 7656023 DOI: 10.1038/Nsb0294-89 |
0.435 |
|
| 1994 |
Krugh TR. Drug-DNA interactions Current Opinion in Structural Biology. 4: 351-364. DOI: 10.1016/S0959-440X(94)90103-1 |
0.465 |
|
| 1993 |
O'Handley SF, Sanford DG, Xu R, Lester CC, Hingerty BE, Broyde S, Krugh TR. Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics. Biochemistry. 32: 2481-97. PMID 8448107 DOI: 10.1021/Bi00061A005 |
0.409 |
|
| 1989 |
Krugh TR, Graves DE, Stone MP. Two-dimensional NMR studies on the anthramycin-d(ATGCAT)2 adduct Biochemistry. 28: 9988-9994. PMID 2620069 DOI: 10.1021/Bi00452A017 |
0.423 |
|
| 1986 |
Lamos ML, Terrance Walker G, Krugh TR, Turner DH. Fluorescence-detected circular dichroism of ethidium bound to poly(dG-dC) and poly(dG-m5dC) under B- and Z-form conditions Biochemistry. 25: 687-691. PMID 3955024 DOI: 10.1021/Bi00351A027 |
0.366 |
|
| 1986 |
Rosenberg LS, Carvlin MJ, Krugh TR. The antitumor agent mitoxantrone binds cooperatively to DNA: Evidence for heterogeneity in DNA conformation Biochemistry. 25: 1002-1008. DOI: 10.1021/Bi00353A008 |
0.394 |
|
| 1985 |
Graves DE, Stone MP, Krugh TR. Structure of the anthramycin-d(ATGCAT)2 adduct from one- and two-dimensional proton NMR experiments in solution Biochemistry. 24: 7573-7581. PMID 4092025 DOI: 10.1021/Bi00347A011 |
0.416 |
|
| 1985 |
Terrance Walker G, Stone MP, Krugh TR. Ethidium binding to left-handed (Z) DNAs results in regions of right-handed DNA at the intercalation site Biochemistry. 24: 7462-7471. PMID 4084593 DOI: 10.1021/Bi00346A065 |
0.39 |
|
| 1985 |
Sanford DG, Krugh TR. N-acetoxy-2-acetylaminofluorene modification of a deoxyoligonucleotide duplex Nucleic Acids Research. 13: 5907-5917. PMID 4034398 DOI: 10.1093/Nar/13.16.5907 |
0.376 |
|
| 1984 |
Graves DE, Pattaroni C, Krishnan BS, Ostrander JM, Hurley LH, Krugh TR. The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct. The Journal of Biological Chemistry. 259: 8202-9. PMID 6736032 |
0.314 |
|
| 1983 |
Graves DE, Krugh TR. Adriamycin and daunorubicin bind in a cooperative manner to deoxyribonucleic acid Biochemistry. 22: 3941-3947. PMID 6615810 DOI: 10.1021/Bi00285A033 |
0.379 |
|
| 1983 |
Graves DE, Krugh TR. Single-cell partition analysis-A direct fluorescence technique for examining ligand-macromolecule interactions Analytical Biochemistry. 134: 73-81. PMID 6362483 DOI: 10.1016/0003-2697(83)90265-8 |
0.336 |
|
| 1982 |
Winkle SA, Rosenberg LS, Krugh TR. On the cooperative and noncooperative binding of ethidium to DNA Nucleic Acids Research. 10: 8211-8223. PMID 7162990 DOI: 10.1093/Nar/10.24.8211 |
0.379 |
|
| 1981 |
Krugh TR, Winkle SA, Graves DE. Solute enhanced partition analysis-A novel method for measuring the binding of drugs to DNA Biochemical and Biophysical Research Communications. 98: 317-323. PMID 7194043 DOI: 10.1016/0006-291X(81)91905-7 |
0.363 |
|
| 1981 |
Winkle SA, Krugh TR. Equilibrium binding of carcinogens and antitumor antibiotics to DNA: Site selectivity, cooperativity, allosterism Nucleic Acids Research. 9: 3175-3186. PMID 6456451 DOI: 10.1093/Nar/9.13.3175 |
0.402 |
|
| 1980 |
Chen Chiao YC, Gurudath Rao K, Hook JW, Krugh TR, Sengupta SK. 7-Amino-actinomycin D complexes with deoxynucleotides as models for the binding of the drug to DNA. Biopolymers. 18: 1749-62. PMID 540129 DOI: 10.1002/Bip.1979.360180712 |
0.392 |
|
| 1979 |
Kastrup RV, Young MA, Krugh TR. Ethidium bromide complexes with self-complementary deoxytetranucleotides. Demonstration and discussion of sequence preferences in the intercalative binding of ethidium bromide. Biochemistry. 17: 4855-65. PMID 718860 DOI: 10.1021/Bi00616A002 |
0.347 |
|
| 1978 |
Auer HE, Pawlowski-Konopnicki BE, Chen Chiao YC, Krugh TR. Resolution of electronic absorption bands and nucleotide binding processes in actinomycin D Biopolymers. 17: 1891-1911. DOI: 10.1002/Bip.1978.360170807 |
0.378 |
|
| 1977 |
Krugh TR, Young MA. Daunorubicin and adriamycin facilitate actinomycin D binding to poly(dA-dT)·poly(dA-dT) Nature. 269: 627-628. PMID 917115 DOI: 10.1038/269627A0 |
0.407 |
|
| 1977 |
Reinhardt CG, Krugh TR. Phosphorus-31 nuclear magnetic resonance studies of actinomycin D, ethidium bromide, and 9-aminoacridine complexes with dinucleotides Biochemistry. 16: 2890-2895. PMID 880285 DOI: 10.1021/Bi00632A014 |
0.376 |
|
| 1977 |
Krugh TR, Mooberry ES, Chiao YCC. Proton magnetic resonance studies of actinomycin D complexes with mixtures of nucleotides as models for the binding of the drug to DNA Biochemistry. 16: 740-747. PMID 836812 DOI: 10.1021/Bi00623A028 |
0.452 |
|
| 1977 |
Chiao YCC, Krugh TR. Actinomycin D complexes with oligonucleotides as models for the binding of the drug to DNA. Paramagnetic induced relaxation experiments on drug-nucleic acid complexes Biochemistry. 16: 747-755. PMID 189809 DOI: 10.1021/Bi00623A029 |
0.403 |
|
| 1976 |
Krugh TR, Laing JW, Young MA. Hydrogen bonded complexes of the ribodinucleoside monophosphates in aqueous solution. Proton magnetic resonance studies Biochemistry. 15: 1224-1228. PMID 1252443 DOI: 10.1021/Bi00651A008 |
0.416 |
|
| 1975 |
Krugh TR, Chen YC. Actinomycin D-deoxynucleotide complexes as models for the actinomycin D-DNA complex. the use of nuclear magnetic resonance to determine the stoichiometry and the geometry of the complexes Biochemistry. 14: 4912-4922. PMID 1182128 DOI: 10.1021/Bi00693A021 |
0.416 |
|
| 1975 |
Young MA, Krugh TR. Proton magnetic resonance studies of double helical oligonucleotides. the effect of base sequence on the stability of deoxydinucleotide dimers Biochemistry. 14: 4841-4847. PMID 1182123 DOI: 10.1021/Bi00693A011 |
0.383 |
|
| 1975 |
Krugh TR, Reinhardt CG. Evidence for sequence preferences in the intercalative binding of ethidium bromide to dinucleoside monophosphates Journal of Molecular Biology. 97: 133-162. PMID 1177318 DOI: 10.1016/S0022-2836(75)80031-3 |
0.459 |
|
| 1975 |
Krugh TR, Wittlin FN, Cramer SP. Ethidium bromide dinucleotide complexes. Evidence for intercalation and sequence preferences in binding to double stranded nucleic acids Biopolymers. 14: 197-210. PMID 1174653 DOI: 10.1002/Bip.1975.360140114 |
0.472 |
|
| 1975 |
Krugh TR, Young MA. Nuclear magnetic resonance studies of hydrogen bonded complexes of oligonucleotides in aqueous solution. I. pdG-dC and pdG-dT Biochemical and Biophysical Research Communications. 62: 1025-1031. PMID 1120083 DOI: 10.1016/0006-291X(75)90425-8 |
0.384 |
|
| 1973 |
Krugh TR, Neely JW. Actinomycin D-deoxydinucleotide interactions as a model for binding of the drug to deoxyribonucleic acid. Proton magnetic resonance results Biochemistry. 12: 4418-4425. PMID 4750253 DOI: 10.1021/Bi00746A019 |
0.428 |
|
| 1973 |
Krugh TR, Neely JW. Actinomycin D-mononucleotide interactions as studied by proton magnetic resonance Biochemistry. 12: 1775-1782. PMID 4699237 DOI: 10.1021/Bi00733A018 |
0.437 |
|
| 1971 |
Krugh TR. Proximity of the nucleoside monophosphate and triphosphate binding sites on deoxyribonucleic acid polymerase Biochemistry. 10: 2594-2599. PMID 4934116 DOI: 10.1021/Bi00789A028 |
0.374 |
|
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