Gilbert Arthur - Publications

Affiliations: 
University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Biochemistry
Website:
http://umanitoba.ca/faculties/health_sciences/medicine/units/biochem/faculty/g_arthur.html

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ogunsina M, Samadder P, Idowu T, Nachtigal M, Schweizer F, Arthur G. Syntheses of L-Rhamnose-Linked Amino Glycerolipids and Their Cytotoxic Activities against Human Cancer Cells. Molecules (Basel, Switzerland). 25. PMID 32012953 DOI: 10.3390/Molecules25030566  0.305
2020 Nachtigal MW, Schweizer F, Arthur G. Abstract A56: Novel L-sugar linked glycosylated antitumor ether lipids for killing platinum-resistant human epithelial ovarian cancer cells Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-A56  0.329
2018 Domalaon R, Sanchak Y, Koskei LC, Lyu Y, Zhanel GG, Arthur G, Schweizer F. Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant. Antimicrobial Agents and Chemotherapy. PMID 29437631 DOI: 10.1128/Aac.02374-17  0.32
2017 Idowu T, Samadder P, Arthur G, Schweizer FM. Amphiphilic-Modulation of Glycosylated Antitumor Ether Lipids Results in a potent Triamino Scaffold against Epithelial Cancer Cell Lines and BT474 Cancer Stem Cells. Journal of Medicinal Chemistry. PMID 29043812 DOI: 10.1021/Acs.Jmedchem.7B01198  0.316
2016 Domalaon R, Findlay B, Ogunsina M, Arthur G, Schweizer F. Ultrashort cationic lipopeptides and lipopeptoids: Evaluation and mechanistic insights against epithelial cancer cells. Peptides. PMID 27486068 DOI: 10.1016/J.Peptides.2016.07.007  0.362
2016 Idowu T, Samadder P, Arthur G, Schweizer F. Design, synthesis and antitumor properties of glycosylated antitumor ether lipid (GAEL)- chlorambucil-hybrids. Chemistry and Physics of Lipids. 194: 139-48. PMID 26188768 DOI: 10.1016/J.Chemphyslip.2015.07.003  0.357
2016 Ogunsina M, Samadder P, Idowu T, Arthur G, Schweizer F. Design, synthesis and evaluation of cytotoxic properties of bisamino glucosylated antitumor ether lipids against cancer cells and cancer stem cells Medchemcomm. 7: 2100-2110. DOI: 10.1039/C6Md00328A  0.304
2015 Mahendran A, Ghogare AA, Bittman R, Arthur G, Greer A. Synthesis and antiproliferative properties of a new ceramide analog of varacin. Chemistry and Physics of Lipids. PMID 26254858 DOI: 10.1016/J.Chemphyslip.2015.07.023  0.316
2014 Samadder P, Xu Y, Schweizer F, Arthur G. Cytotoxic properties of D-gluco-, D-galacto- and D-manno-configured 2-amino-2-deoxy-glycerolipids against epithelial cancer cell lines and BT-474 breast cancer stem cells. European Journal of Medicinal Chemistry. 78: 225-35. PMID 24681987 DOI: 10.1016/J.Ejmech.2014.03.057  0.321
2014 Samadder P, Byun HS, Bittman R, Arthur G. A fluorescent alkyllysophospholipid analog exhibits selective cytotoxicity against the hormone-insensitive prostate cancer cell line PC3. Anti-Cancer Agents in Medicinal Chemistry. 14: 528-38. PMID 24628239 DOI: 10.2174/1871520614666140309223603  0.31
2014 Arthur G, Bittman R. Glycosylated antitumor ether lipids: activity and mechanism of action. Anti-Cancer Agents in Medicinal Chemistry. 14: 592-606. PMID 24628233 DOI: 10.2174/1871520614666140309231144  0.381
2013 Ogunsina M, Pan H, Samadder P, Arthur G, Schweizer F. Structure activity relationships of N-linked and diglycosylated glucosamine-based antitumor glycerolipids. Molecules (Basel, Switzerland). 18: 15288-304. PMID 24335578 DOI: 10.3390/Molecules181215288  0.33
2013 Xu Y, Ogunsina M, Samadder P, Arthur G, Schweizer F. Structure-activity relationships of glucosamine-derived glycerolipids: the role of the anomeric linkage, the cationic charge and the glycero moiety on the antitumor activity. Chemmedchem. 8: 511-20. PMID 23322648 DOI: 10.1002/Cmdc.201200489  0.326
2010 Mahendran A, Vuong A, Aebisher D, Gong Y, Bittman R, Arthur G, Kawamura A, Greer A. Synthesis, characterization, mechanism of decomposition, and antiproliferative activity of a class of PEGylated benzopolysulfanes structurally similar to the natural product varacin. The Journal of Organic Chemistry. 75: 5549-57. PMID 20704430 DOI: 10.1021/Jo100870Q  0.325
2010 Byun HS, Bittman R, Samadder P, Arthur G. Synthesis and antitumor activity of ether glycerophospholipids bearing a carbamate moiety at the sn-2 position: selective sensitivity against prostate cancer cell lines. Chemmedchem. 5: 1045-52. PMID 20533503 DOI: 10.1002/Cmdc.201000060  0.319
2007 Bittman R, Li Z, Samadder P, Arthur G. Anticancer activity of a ceramide analog containing a disulfide linkage. Cancer Letters. 251: 53-8. PMID 17141948 DOI: 10.1016/J.Canlet.2006.10.026  0.365
2007 Lin W, Arthur G. Phospholipids are synthesized in the G2/M phase of the cell cycle. The International Journal of Biochemistry & Cell Biology. 39: 597-605. PMID 17113814 DOI: 10.1016/J.Biocel.2006.10.011  0.527
2006 Lin W, Arthur G. Phosphatidylcholine catabolism in the MCF-7 cell cycle. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 737-44. PMID 17167537 DOI: 10.1139/o06-046  0.48
2005 Lu X, Arthur G, Bittman R. Synthesis of a novel ceramide analogue via Tebbe methylenation and evaluation of its antiproliferative activity. Organic Letters. 7: 1645-8. PMID 15816773 DOI: 10.1021/Ol0503440  0.326
2004 Samadder P, Bittman R, Byun HS, Arthur G. Synthesis and use of novel ether phospholipid enantiomers to probe the molecular basis of the antitumor Effects of alkyllysophospholipids: correlation of differential activation of c-Jun NH(2)-terminal protein kinase with antiproliferative effects in neuronal tumor cells. Journal of Medicinal Chemistry. 47: 2710-3. PMID 15115414 DOI: 10.1021/Jm0302748  0.351
2001 Yang G, Franck RW, Bittman R, Samadder P, Arthur G. Synthesis and growth inhibitory properties of glucosamine-derived glycerolipids. Organic Letters. 3: 197-200. PMID 11430033 DOI: 10.1021/Ol006783A  0.304
2001 Li G, Samadder P, Arthur G, Bittman R. Synthesis and antiproliferative properties of a photoactivatable analogue of ET-18-OCH3 Tetrahedron. 57: 8925-8932. DOI: 10.1016/S0040-4020(01)00901-2  0.36
2001 Bittman R, Qin D, Wong D, Tigyi G, Samadder P, Arthur G. Synthesis and antitumor properties of a plasmalogen methyl ether analogue Tetrahedron. 57: 4277-4282. DOI: 10.1016/S0040-4020(01)00371-4  0.338
2000 Liang B, McMaster JC, Kroeger EA, Hatch GM, Mymin D, Dembinski T, Arthur G, Shen G, Man RYK, Choy PC. The effect of fenofibrate treatment on endothelium-dependent relaxation induced by oxidative modified low density lipoprotein from hyperlipidemic patients Molecular and Cellular Biochemistry. 207: 123-129. PMID 10888237 DOI: 10.1023/A:1007019019911  0.527
2000 Yang G, Franck RW, Byun HS, Bittman R, Samadder P, Arthur G. Convergent C-glycolipid synthesis via the Ramberg-Bäcklund reaction: active antiproliferative glycolipids. Organic Letters. 1: 2149-51. PMID 10836068 DOI: 10.1021/Ol991211F  0.325
1999 Lin W, Leung LW, Bae YS, Bittman R, Arthur G. Effects of a water-soluble antitumor ether phosphonoinositide, D-myo-inositol 4-(hexadecyloxy)-3(S)-methoxybutanephosphonate (C4-PI), on inositol lipid metabolism in breast epithelial cancer cell lines. Biochemical Pharmacology. 57: 1153-8. PMID 11230803 DOI: 10.1016/S0006-2952(99)00019-2  0.584
1998 Leung LW, Lin W, Richard C, Bittman R, Arthur G. A Novel Water-Soluble Phosphonate Analog of Phosphatidylinositol, D-Myo-Inositol4-(Hexadecyloxy)-3(5)-Methoxybutanephosphonate (C4-PI), Inhibits Epithelial Cell Proliferation and is a Substrate but not an Inhibitor of Phosphatidylinositol 3-Kinase Journal of Liposome Research. 8: 213-224. DOI: 10.3109/08982109809035527  0.543
1997 Zhou X, Arthur G. 1-O-Octadecyl-2-O-methylglycerophosphocholine inhibits protein kinase C-dependent phosphorylation of endogenous proteins in MCF-7 cells Biochemical Journal. 324: 897-902. PMID 9210414 DOI: 10.1042/Bj3240897  0.332
1997 Bittman R, Byun HS, Reddy KC, Samadder P, Arthur G. Enantioselective synthesis and antiproliferative properties of an ilmofosine analog, 2'-(trimethylammonio)ethyl 3-(hexadecyloxy)-2-(methoxymethyl)propyl phosphate, on epithelial cancer cell growth. Journal of Medicinal Chemistry. 40: 1391-5. PMID 9135036 DOI: 10.1021/Jm960165B  0.33
1996 Zhou X, Lu X, Richard C, Xiong W, Litchfield DW, Bittman R, Arthur G. 1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells. The Journal of Clinical Investigation. 98: 937-44. PMID 8770865 DOI: 10.1172/Jci118877  0.329
1996 Erukulla RK, Zhou X, Samadder P, Arthur G, Bittman R. Synthesis and Evaluation of the Antiproliferative Effects of 1-O-Hexadecyl-2-O- methyl-3-O-(2‘-acetamido-2‘-deoxy-β-d-glucopyranosyl)-sn-glycerol and 1-O-Hexadecyl-2-O-methyl-3-O-(2‘-amino-2‘-deoxy-β-d-glucopyranosyl)-sn-glycerol on Epithelial Cancer Cell Growth Journal of Medicinal Chemistry. 39: 1545-1548. PMID 8691486 DOI: 10.1021/Jm950928F  0.306
1995 Badiani K, Arthur G. Evidence for receptor and G-protein regulation of a phosphatidylethanolamine-hydrolysing phospbolipase A1 in guinea-pig heart microsomes: Stimulation of phospholipase A1 activity by DL-isoprenaline and guanine nucleotides Biochemical Journal. 312: 805-809. PMID 8554524 DOI: 10.1042/Bj3120805  0.348
1995 Zhou X, Arthur G. Effect of 1-0-octadecyl-2-O-methyl-glycerophosphocholine on phosphatidylcholine and phosphatidylethanolamine synthesis in MCF-7 and A549 cells and its relationship to inhibition of cell proliferation European Journal of Biochemistry. 232: 881-888. PMID 7588730 DOI: 10.1111/J.1432-1033.1995.881Zz.X  0.401
1993 Lu X, Zhou X, Kardash D, Arthur G. Metabolism of alkyl lysophospholipid in epithelial cancer cell lines and inhibition of cell growth. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 71: 122-6. PMID 8398069 DOI: 10.1139/O93-020  0.324
1993 Badiani K, Lu X, Arthur G. Effect of Δ9-tetrahydrocannabinol and merthiolate on acyltransferase activities in guinea pig liver microsomesand merthiolate on acyltransferase activities in guinea pig liver microsomes Lipids. 28: 299-303. PMID 8387622 DOI: 10.1007/Bf02536314  0.369
1993 Arthur G, Lu X. The ethanolamine requirement of keratinocytes for growth is not due to defective synthesis of ethanolamine phosphoacylglycerols by the decarboxylation pathway Biochemical Journal. 293: 125-130. PMID 8328953 DOI: 10.1042/Bj2930125  0.326
1992 Badiani K, Lu X, Arthur G. Evidence for the regulation of guinea-pig heart microsomal phosphatidylcholine-hydrolysing phospholipase A1 by guanosine 5'-[γ-thio]triphosphate Biochemical Journal. 288: 965-968. PMID 1472009 DOI: 10.1042/Bj2880965  0.426
1991 Badiani K, Arthur G. 2-Acyl-sn-glycero-3-phosphoethanolamine lysophospholipase A2 activity in guinea-pig heart microsomes Biochemical Journal. 275: 393-398. PMID 2025224 DOI: 10.1042/Bj2750393  0.43
1991 Arthur G, Page L. Synthesis of phosphatidylethanolamine and ethanolamine plasmalogen by the CDP-ethanolamine and decarboxylase pathways in rat heart, kidney and liver Biochemical Journal. 273: 121-125. PMID 1989575 DOI: 10.1042/Bj2730121  0.381
1990 Badiani K, Page L, Arthur G. Hydrolysis of 2-acyl-sn-glycero-3-phosphocholines in guinea pig heart mitochondria Biochemistry and Cell Biology. 68: 1090-1095. PMID 2257116 DOI: 10.1139/O90-163  0.417
1989 Arthur G. Lysophospholipase A2 activity in guinea-pig heart microsomal fractions displaying high activities with 2-acylglycerophosphocholines with linoleic and arachidonic acids Biochemical Journal. 261: 581-586. PMID 2775235 DOI: 10.1042/Bj2610581  0.439
1989 Arthur G. Acylation of 2-acyl-glycerophosphocholine in guinea-pig heart microsomal fractions Biochemical Journal. 261: 575-580. PMID 2775234 DOI: 10.1042/Bj2610575  0.445
1988 Giffin M, Arthur G, Choy PC, Man RYK. Lysophosphatidylcholine metabolism and cardiac arrhythmias Canadian Journal of Physiology and Pharmacology. 66: 185-189. PMID 3383014 DOI: 10.1139/Y88-032  0.602
1987 Arthur G, Page L, Choy PC. Acylation of 1-alkenylglycerophosphoethanolamine and 1-acylglycerophosphoethanolamine in guinea-pig heart microsomes Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 921: 259-265. PMID 3651487 DOI: 10.1016/0005-2760(87)90026-9  0.653
1987 Arthur G, Zaborniak CL, Choy PC. The presence of 1-radyl-glycerophosphoethanolamine acyltransferase activity in guinea pig heart mitochondria Biochemistry and Cell Biology. 65: 1016-1021. PMID 3454183 DOI: 10.1139/O87-133  0.633
1987 Cao YZ, Tam SW, Arthur G, Chen H, Choy PC. The purification and characterization of a phospholipase A in hamster heart cytosol for the hydrolysis of phosphatidylcholine. The Journal of Biological Chemistry. 262: 16927-35. PMID 3119595  0.572
1987 Arthur G, Page LL, Zaborniak CL, Choy PC. The acylation of lysophosphoradylglycerocholines in guinea-pig heart mitochondria Biochemical Journal. 242: 171-175. PMID 3036082 DOI: 10.1042/Bj2420171  0.643
1986 Arthur G, Choy PC. Acylation of 1-alkenyl-glycerophosphocholine and 1-acyl-glycerophosphocholine in guinea pig heart Biochemical Journal. 236: 481-487. PMID 3753462  0.58
1986 Arthur G, Page L, Mock T, Choy PC. The catabolism of plasmenylcholine in the guinea pig heart. The Biochemical Journal. 236: 475-80. PMID 3753461 DOI: 10.1042/Bj2360475  0.644
1986 Mock T, Slater TL, Arthur G, Chan AC, Choy PC. Effects of fatty acids on phosphatidylcholine biosynthesis in isolated hamster heart. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 64: 413-7. PMID 3013250 DOI: 10.1139/O86-058  0.634
1985 Wientzek M, Arthur G, Man RYK, Choy PC. A sensitive method for the quantitation of lysophosphatidylcholine in canine heart Journal of Lipid Research. 26: 1166-1169. PMID 4067437  0.546
1985 Arthur G, Mock T, Zaborniak C, Choy PC. The distribution and acyl composition of plasmalogens in guinea pig heart. Lipids. 20: 693-8. PMID 4058266 DOI: 10.1007/Bf02534389  0.639
1985 Arthur G, Covic L, Wientzek M, Choy PC. Plasmalogenase in hamster heart Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 833: 189-195. PMID 3970950 DOI: 10.1016/0005-2760(85)90189-4  0.641
1985 Arthur G, Choy PC. 1-Alkenyl glycerophosphocholine: Acyl CoA acyl transferase activities in mammalian hearts Federation Proceedings. 44.  0.607
1984 Arthur G, Tam SW, Choy PC. The effects of detergents on CDP-choline:1,2-diacylglycerol phosphocholine transferase from hamster heart Canadian Journal of Biochemistry and Cell Biology. 62: 1059-1063. PMID 6098357  0.573
1984 Arthur G, Choy PC. Acyl specificity of hamster heart CDP-choline 1,2-diacylglycerol phosphocholine transferase in phosphatidylcholine biosynthesis Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 795: 221-229. PMID 6089897 DOI: 10.1016/0005-2760(84)90069-9  0.654
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