| Year |
Citation |
Score |
| 2023 |
Lee G, Muir TW. Distinct phases of cellular signaling revealed by time-resolved protein synthesis. Biorxiv : the Preprint Server For Biology. PMID 37503273 DOI: 10.1101/2023.07.10.548208 |
0.306 |
|
| 2023 |
Hananya N, Ye X, Koren S, Muir TW. A genetically encoded photoproximity labeling approach for mapping protein territories. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219339120. PMID 37036999 DOI: 10.1073/pnas.2219339120 |
0.34 |
|
| 2022 |
Sekar G, Stevens AJ, Mostafavi AZ, Sashi P, Muir TW, Cowburn D. A Conserved Histidine Residue Drives Extein Dependence in an Enhanced Atypically Split Intein. Journal of the American Chemical Society. 144: 19196-19203. PMID 36194550 DOI: 10.1021/jacs.2c08985 |
0.555 |
|
| 2020 |
Burton AJ, Haugbro M, Parisi E, Muir TW. Live-cell protein engineering with an ultra-short split intein. Proceedings of the National Academy of Sciences of the United States of America. 117: 12041-12049. PMID 32424098 DOI: 10.1073/Pnas.2003613117 |
0.391 |
|
| 2019 |
Gramespacher JA, Burton AJ, Guerra LF, Muir TW. Proximity Induced Splicing Utilizing Caged Split Inteins. Journal of the American Chemical Society. PMID 31418547 DOI: 10.1021/Jacs.9B05721 |
0.339 |
|
| 2019 |
Thompson RE, Stevens AJ, Muir TW. Protein engineering through tandem transamidation. Nature Chemistry. PMID 31263208 DOI: 10.1038/S41557-019-0281-2 |
0.371 |
|
| 2018 |
Stevens AJ, Sekar G, Gramespacher JA, Cowburn D, Muir TW. An Atypical Mechanism of Split Intein Molecular Recognition and Folding. Journal of the American Chemical Society. PMID 30156841 DOI: 10.1021/Jacs.8B07334 |
0.604 |
|
| 2018 |
Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, ... Muir TW, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/Nchembio.2576 |
0.322 |
|
| 2017 |
Gramespacher JA, Stevens AJ, Thompson RE, Muir TW. Improved Protein Splicing Using Embedded Split Inteins. Protein Science : a Publication of the Protein Society. PMID 29226478 DOI: 10.1002/Pro.3357 |
0.358 |
|
| 2017 |
Stevens AJ, Sekar G, Shah NH, Mostafavi AZ, Cowburn D, Muir TW. A promiscuous split intein with expanded protein engineering applications. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739907 DOI: 10.1073/Pnas.1701083114 |
0.593 |
|
| 2016 |
Stevens AJ, Brown ZZ, Shah NH, Sekar G, Cowburn D, Muir TW. Design of a Split Intein with Exceptional Protein Splicing Activity. Journal of the American Chemical Society. PMID 26854538 DOI: 10.1021/Jacs.5B13528 |
0.607 |
|
| 2015 |
Holt M, Muir T. Application of the protein semisynthesis strategy to the generation of modified chromatin. Annual Review of Biochemistry. 84: 265-90. PMID 25784050 DOI: 10.1146/Annurev-Biochem-060614-034429 |
0.353 |
|
| 2014 |
Liu Z, Frutos S, Bick MJ, Vila-Perelló M, Debelouchina GT, Darst SA, Muir TW. Structure of the branched intermediate in protein splicing. Proceedings of the National Academy of Sciences of the United States of America. 111: 8422-7. PMID 24778214 DOI: 10.1073/Pnas.1402942111 |
0.36 |
|
| 2014 |
Eryilmaz E, Shah NH, Muir TW, Cowburn D. Structural and dynamical features of inteins and implications on protein splicing. The Journal of Biological Chemistry. 289: 14506-11. PMID 24695731 DOI: 10.1074/Jbc.R113.540302 |
0.616 |
|
| 2014 |
Shah NH, Muir TW. Inteins: Nature's Gift to Protein Chemists. Chemical Science (Royal Society of Chemistry : 2010). 5: 446-461. PMID 24634716 DOI: 10.1039/C3Sc52951G |
0.395 |
|
| 2014 |
Eryilmaz E, Shah NH, Muir TW, Cowburn D. Structural and dynamical features of inteins and implications on protein splicing (Journal of Biological Chemistry (2014) 289 (14506-14511)) Journal of Biological Chemistry. 289: 19278. DOI: 10.1074/Jbc.A113.540302 |
0.548 |
|
| 2013 |
Shah NH, Eryilmaz E, Cowburn D, Muir TW. Naturally split inteins assemble through a "capture and collapse" mechanism. Journal of the American Chemical Society. 135: 18673-81. PMID 24236406 DOI: 10.1021/Ja4104364 |
0.6 |
|
| 2013 |
Shah NH, Eryilmaz E, Cowburn D, Muir TW. Extein residues play an intimate role in the rate-limiting step of protein trans-splicing. Journal of the American Chemical Society. 135: 5839-47. PMID 23506399 DOI: 10.1021/Ja401015P |
0.634 |
|
| 2013 |
Vila-Perelló M, Liu Z, Shah NH, Willis JA, Idoyaga J, Muir TW. Streamlined expressed protein ligation using split inteins. Journal of the American Chemical Society. 135: 286-92. PMID 23265282 DOI: 10.1021/Ja309126M |
0.397 |
|
| 2012 |
Shah NH, Dann GP, Vila-Perelló M, Liu Z, Muir TW. Ultrafast protein splicing is common among cyanobacterial split inteins: implications for protein engineering. Journal of the American Chemical Society. 134: 11338-41. PMID 22734434 DOI: 10.1021/Ja303226X |
0.363 |
|
| 2011 |
Shah NH, Muir TW. Split Inteins: Nature's Protein Ligases. Israel Journal of Chemistry. 51: 854-861. PMID 23620603 DOI: 10.1002/Ijch.201100094 |
0.351 |
|
| 2011 |
Shah NH, Vila-Perelló M, Muir TW. Kinetic control of one-pot trans-splicing reactions by using a wild-type and designed split intein. Angewandte Chemie (International Ed. in English). 50: 6511-5. PMID 21656885 DOI: 10.1002/Anie.201102909 |
0.397 |
|
| 2011 |
Cho JH, Muralidharan V, Vila-Perello M, Raleigh DP, Muir TW, Palmer AG. Tuning protein autoinhibition by domain destabilization. Nature Structural & Molecular Biology. 18: 550-5. PMID 21532593 DOI: 10.1038/Nsmb.2039 |
0.332 |
|
| 2010 |
Vila-Perelló M, Muir TW. Biological applications of protein splicing. Cell. 143: 191-200. PMID 20946979 DOI: 10.1016/J.Cell.2010.09.031 |
0.371 |
|
| 2010 |
Frutos S, Goger M, Giovani B, Cowburn D, Muir TW. Branched intermediate formation stimulates peptide bond cleavage in protein splicing. Nature Chemical Biology. 6: 527-33. PMID 20495572 DOI: 10.1038/Nchembio.371 |
0.593 |
|
| 2009 |
McGinty RK, Chatterjee C, Muir TW. Semisynthesis of ubiquitylated proteins. Methods in Enzymology. 462: 225-43. PMID 19632477 DOI: 10.1016/S0076-6879(09)62011-5 |
0.366 |
|
| 2009 |
Lockless SW, Muir TW. Traceless protein splicing utilizing evolved split inteins. Proceedings of the National Academy of Sciences of the United States of America. 106: 10999-1004. PMID 19541616 DOI: 10.1073/Pnas.0902964106 |
0.349 |
|
| 2009 |
Flavell RR, Muir TW. Expressed protein ligation (EPL) in the study of signal transduction, ion conduction, and chromatin biology. Accounts of Chemical Research. 42: 107-16. PMID 18939858 DOI: 10.1021/Ar800129C |
0.336 |
|
| 2008 |
Schwartz EC, Shekhtman A, Dutta K, Pratt MR, Cowburn D, Darst S, Muir TW. A full-length group 1 bacterial sigma factor adopts a compact structure incompatible with DNA binding. Chemistry & Biology. 15: 1091-103. PMID 18940669 DOI: 10.1016/J.Chembiol.2008.09.008 |
0.488 |
|
| 2008 |
Muir TW. Studying protein structure and function using semisynthesis. Biopolymers. 90: 743-50. PMID 18924136 DOI: 10.1002/Bip.21102 |
0.382 |
|
| 2008 |
Singla N, Himanen JP, Muir TW, Nikolov DB. Toward the semisynthesis of multidomain transmembrane receptors: modification of Eph tyrosine kinases. Protein Science : a Publication of the Protein Society. 17: 1740-7. PMID 18628240 DOI: 10.1110/Ps.035659.108 |
0.375 |
|
| 2008 |
Tyszkiewicz AB, Muir TW. Activation of protein splicing with light in yeast. Nature Methods. 5: 303-5. PMID 18272963 DOI: 10.1038/Nmeth.1189 |
0.325 |
|
| 2008 |
Ottesen JJ, Bar-Dagan M, Giovani B, Muir TW. An amalgamation of solid phase peptide synthesis and ribosomal peptide synthesis. Biopolymers. 90: 406-14. PMID 17636509 DOI: 10.1002/Bip.20810 |
0.386 |
|
| 2007 |
Hahn ME, Pellois JP, Vila-Perelló M, Muir TW. Tunable photoactivation of a post-translationally modified signaling protein and its unmodified counterpart in live cells. Chembiochem : a European Journal of Chemical Biology. 8: 2100-5. PMID 17907120 DOI: 10.1002/Cbic.200700404 |
0.331 |
|
| 2007 |
Vila-Perelló M, Pratt MR, Tulin F, Muir TW. Covalent capture of phospho-dependent protein oligomerization by site-specific incorporation of a diazirine photo-cross-linker. Journal of the American Chemical Society. 129: 8068-9. PMID 17567014 DOI: 10.1021/Ja072013J |
0.349 |
|
| 2007 |
Pratt MR, Schwartz EC, Muir TW. Small-molecule-mediated rescue of protein function by an inducible proteolytic shunt. Proceedings of the National Academy of Sciences of the United States of America. 104: 11209-14. PMID 17563385 DOI: 10.1073/Pnas.0700816104 |
0.364 |
|
| 2006 |
Pellois JP, Muir TW. Semisynthetic proteins in mechanistic studies: using chemistry to go where nature can't. Current Opinion in Chemical Biology. 10: 487-91. PMID 16935551 DOI: 10.1016/J.Cbpa.2006.08.016 |
0.37 |
|
| 2006 |
Muralidharan V, Dutta K, Cho J, Vila-Perello M, Raleigh DP, Cowburn D, Muir TW. Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II. Biochemistry. 45: 8874-84. PMID 16846230 DOI: 10.1021/Bi060590Z |
0.509 |
|
| 2006 |
Muralidharan V, Muir TW. Protein ligation: an enabling technology for the biophysical analysis of proteins. Nature Methods. 3: 429-38. PMID 16721376 DOI: 10.1038/Nmeth886 |
0.377 |
|
| 2006 |
Muir T. Posttranslational Modification of Proteins: Expanding Nature's Inventory. By Christopher T. Walsh. Chembiochem. 7: 1623-1624. DOI: 10.1002/Cbic.200600342 |
0.356 |
|
| 2005 |
Shi J, Muir TW. Development of a tandem protein trans-splicing system based on native and engineered split inteins. Journal of the American Chemical Society. 127: 6198-206. PMID 15853324 DOI: 10.1021/Ja042287W |
0.357 |
|
| 2004 |
Muralidharan V, Cho J, Trester-Zedlitz M, Kowalik L, Chait BT, Raleigh DP, Muir TW. Domain-specific incorporation of noninvasive optical probes into recombinant proteins. Journal of the American Chemical Society. 126: 14004-12. PMID 15506763 DOI: 10.1021/Ja0466199 |
0.343 |
|
| 2004 |
Mootz HD, Blum ES, Muir TW. Activation of an autoregulated protein kinase by conditional protein splicing. Angewandte Chemie (International Ed. in English). 43: 5189-92. PMID 15455415 DOI: 10.1002/Anie.200460941 |
0.309 |
|
| 2004 |
Cowburn D, Shekhtman A, Xu R, Ottesen JJ, Muir TW. Segmental isotopic labeling for structural biological applications of NMR. Methods in Molecular Biology (Clifton, N.J.). 278: 47-56. PMID 15317990 DOI: 10.1385/1-59259-809-9:047 |
0.578 |
|
| 2004 |
Romanelli A, Shekhtman A, Cowburn D, Muir TW. Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction. Proceedings of the National Academy of Sciences of the United States of America. 101: 6397-402. PMID 15087498 DOI: 10.1073/Pnas.0306616101 |
0.598 |
|
| 2003 |
Wilson KA, Kalkum M, Ottesen J, Yuzenkova J, Chait BT, Landick R, Muir T, Severinov K, Darst SA. Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. Journal of the American Chemical Society. 125: 12475-83. PMID 14531691 DOI: 10.1021/Ja036756Q |
0.331 |
|
| 2003 |
Schwartz EC, Muir TW, Tyszkiewicz AB. "The splice is right": how protein splicing is opening new doors in protein science. Chemical Communications (Cambridge, England). 2087-90. PMID 13678154 DOI: 10.1039/B304989M |
0.326 |
|
| 2003 |
Mootz HD, Blum ES, Tyszkiewicz AB, Muir TW. Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo. Journal of the American Chemical Society. 125: 10561-9. PMID 12940738 DOI: 10.1021/Ja0362813 |
0.392 |
|
| 2003 |
Giriat I, Muir TW. Protein semi-synthesis in living cells. Journal of the American Chemical Society. 125: 7180-1. PMID 12797783 DOI: 10.1021/Ja034736I |
0.362 |
|
| 2003 |
Muir TW. Semisynthesis of proteins by expressed protein ligation. Annual Review of Biochemistry. 72: 249-89. PMID 12626339 DOI: 10.1146/Annurev.Biochem.72.121801.161900 |
0.39 |
|
| 2002 |
Hofmann RM, Muir TW. Recent advances in the application of expressed protein ligation to protein engineering. Current Opinion in Biotechnology. 13: 297-303. PMID 12323349 DOI: 10.1016/S0958-1669(02)00326-9 |
0.351 |
|
| 2002 |
Valiyaveetil FI, MacKinnon R, Muir TW. Semisynthesis and folding of the potassium channel KcsA. Journal of the American Chemical Society. 124: 9113-20. PMID 12149015 DOI: 10.1021/Ja0266722 |
0.334 |
|
| 2002 |
Mootz HD, Muir TW. Protein splicing triggered by a small molecule. Journal of the American Chemical Society. 124: 9044-5. PMID 12148996 DOI: 10.1021/Ja026769O |
0.315 |
|
| 2002 |
Camarero JA, Shekhtman A, Campbell EA, Chlenov M, Gruber TM, Bryant DA, Darst SA, Cowburn D, Muir TW. Autoregulation of a bacterial sigma factor explored by using segmental isotopic labeling and NMR. Proceedings of the National Academy of Sciences of the United States of America. 99: 8536-41. PMID 12084914 DOI: 10.1073/Pnas.132033899 |
0.533 |
|
| 2001 |
Camarero JA, Muir TW. Native chemical ligation of polypeptides. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit18.4. PMID 18429140 DOI: 10.1002/0471140864.Ps1804S15 |
0.329 |
|
| 2001 |
Stanger HE, Syud FA, Espinosa JF, Giriat I, Muir T, Gellman SH. Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure. Proceedings of the National Academy of Sciences of the United States of America. 98: 12015-20. PMID 11593011 DOI: 10.1073/Pnas.211536998 |
0.315 |
|
| 2001 |
Camarero JA, Fushman D, Cowburn D, Muir TW. Peptide chemical ligation inside living cells: in vivo generation of a circular protein domain. Bioorganic & Medicinal Chemistry. 9: 2479-84. PMID 11553489 DOI: 10.1016/S0968-0896(01)00217-6 |
0.573 |
|
| 2001 |
Cowburn D, Muir TW. Segmental isotopic labeling using expressed protein ligation. Methods in Enzymology. 339: 41-54. PMID 11462824 DOI: 10.1016/S0076-6879(01)39308-4 |
0.536 |
|
| 2001 |
Camarero JA, Fushman D, Sato S, Giriat I, Cowburn D, Raleigh DP, Muir TW. Rescuing a destabilized protein fold through backbone cyclization. Journal of Molecular Biology. 308: 1045-62. PMID 11352590 DOI: 10.1006/Jmbi.2001.4631 |
0.604 |
|
| 2001 |
Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB. Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II Oncogene. 20: 951-961. PMID 11314030 DOI: 10.1038/Sj.Onc.1204173 |
0.362 |
|
| 2001 |
Minakhin L, Camarero JA, Holford M, Parker C, Muir TW, Severinov K. Mapping the molecular interface between the sigma(70) subunit of E. coli RNA polymerase and T4 AsiA. Journal of Molecular Biology. 306: 631-42. PMID 11243776 DOI: 10.1006/Jmbi.2001.4445 |
0.621 |
|
| 2000 |
Blaschke UK, Silberstein J, Muir TW. Protein engineering by expressed protein ligation. Methods in Enzymology. 328: 478-96. PMID 11075362 DOI: 10.1016/S0076-6879(00)28414-0 |
0.344 |
|
| 2000 |
Cotton GJ, Muir TW. Generation of a dual-labeled fluorescence biosensor for Crk-II phosphorylation using solid-phase expressed protein ligation. Chemistry & Biology. 7: 253-61. PMID 10780925 DOI: 10.1016/S1074-5521(00)00100-9 |
0.388 |
|
| 2000 |
Huse M, Holford MN, Kuriyan J, Muir TW. Semisynthesis of hyperphosphorylated type I TGFβ receptor: Addressing the mechanism of kinase activation [20] Journal of the American Chemical Society. 122: 8337-8338. DOI: 10.1021/Ja001763P |
0.523 |
|
| 2000 |
Blaschke UK, Cotton GJ, Muir TW. Synthesis of multi-domain proteins using Expressed Protein Ligation: Strategies for segmental isotopic labeling of internal regions Tetrahedron. 56: 9461-9470. DOI: 10.1016/S0040-4020(00)00830-9 |
0.377 |
|
| 1999 |
Ayers B, Blaschke UK, Camarero JA, Cotton GJ, Holford M, Muir TW. Introduction of unnatural amino acids into proteins using expressed protein ligation. Biopolymers. 51: 343-54. PMID 10685045 DOI: 10.1002/(Sici)1097-0282(1999)51:5<343::Aid-Bip4>3.0.Co;2-W |
0.669 |
|
| 1999 |
Layfield R, Franklin K, Landon M, Walker G, Wang P, Ramage R, Brown A, Love S, Urquhart K, Muir T, Baker R, Mayer RJ. Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes. Analytical Biochemistry. 274: 40-9. PMID 10527495 DOI: 10.1006/Abio.1999.4234 |
0.409 |
|
| 1999 |
Cotton GJ, Muir TW. Peptide ligation and its application to protein engineering. Chemistry & Biology. 6: R247-56. PMID 10467135 DOI: 10.1016/S1074-5521(99)80109-4 |
0.328 |
|
| 1999 |
Xu R, Ayers B, Cowburn D, Muir TW. Chemical ligation of folded recombinant proteins: segmental isotopic labeling of domains for NMR studies. Proceedings of the National Academy of Sciences of the United States of America. 96: 388-93. PMID 9892643 DOI: 10.1073/Pnas.96.2.388 |
0.628 |
|
| 1999 |
Camarero JA, Muir TW. Biosynthesis of a head-to-tail cyclized protein with improved biological activity Journal of the American Chemical Society. 121: 5597-5598. DOI: 10.1021/Ja990929N |
0.408 |
|
| 1999 |
Cotton GJ, Ayers B, Xu R, Muir TW. Insertion of a synthetic peptide into a recombinant protein framework: A protein biosensor [7] Journal of the American Chemical Society. 121: 1100-1101. DOI: 10.1021/Ja983804B |
0.338 |
|
| 1998 |
Holford M, Muir TW. Adding 'splice' to protein engineering. Structure (London, England : 1993). 6: 951-6. PMID 9739093 DOI: 10.1016/S0969-2126(98)00097-5 |
0.657 |
|
| 1998 |
Severinov K, Muir TW. Expressed protein ligation, a novel method for studying protein-protein interactions in transcription. The Journal of Biological Chemistry. 273: 16205-9. PMID 9632677 DOI: 10.1074/Jbc.273.26.16205 |
0.397 |
|
| 1998 |
Muir TW, Sondhi D, Cole PA. Expressed protein ligation: a general method for protein engineering. Proceedings of the National Academy of Sciences of the United States of America. 95: 6705-10. PMID 9618476 DOI: 10.1073/Pnas.95.12.6705 |
0.383 |
|
| 1997 |
Muir TW, Dawson PE, Fitzgerald MC, Kent SB. Protein signature analysis: a practical new approach for studying structure-activity relationships in peptides and proteins. Methods in Enzymology. 289: 545-64. PMID 9353737 DOI: 10.1016/S0076-6879(97)89063-5 |
0.368 |
|
| 1997 |
Franklin K, Layfield R, Landon M, Ramage R, Brown A, Love S, Muir T, Urquhart K, Bownes M, Mayer RJ. Capillary electrophoresis assay for ubiquitin carboxyl-terminal hydrolases with chemically synthesized ubiquitin-valine as substrate. Analytical Biochemistry. 247: 305-9. PMID 9177692 DOI: 10.1006/Abio.1997.2099 |
0.391 |
|
| 1997 |
Love SG, Muir TW, Ramage R, Shaw KT, Alexeev D, Sawyer L, Kelly SM, Price NC, Arnold JE, Mee MP, Mayer RJ. Synthetic, structural and biological studies of the ubiquitin system: synthesis and crystal structure of an analogue containing unnatural amino acids. The Biochemical Journal. 323: 727-34. PMID 9169606 DOI: 10.1042/Bj3230727 |
0.305 |
|
| 1997 |
Stewart PL, Chiu CY, Huang S, Muir T, Zhao Y, Chait B, Mathias P, Nemerow GR. Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization Embo Journal. 16: 1189-1198. PMID 9135136 DOI: 10.1093/Emboj/16.6.1189 |
0.306 |
|
| 1996 |
Muir TW, Dawson PE, Fitzgerald MC, Kent SB. Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis. Chemistry & Biology. 3: 817-25. PMID 8939700 DOI: 10.1016/S1074-5521(96)90067-8 |
0.409 |
|
| 1995 |
Muir TW. A chemical approach to the construction of multimeric protein assemblies. Structure (London, England : 1993). 3: 649-52. PMID 8591042 DOI: 10.1016/S0969-2126(01)00200-3 |
0.378 |
|
| 1994 |
Dawson PE, Muir TW, Clark-Lewis I, Kent SB. Synthesis of proteins by native chemical ligation. Science (New York, N.Y.). 266: 776-9. PMID 7973629 |
0.341 |
|
| 1993 |
Muir TW, Kent SB. The chemical synthesis of proteins. Current Opinion in Biotechnology. 4: 420-7. PMID 7763972 DOI: 10.1016/0958-1669(93)90007-J |
0.362 |
|
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