Luke I. Szweda - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Biochemistry

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Makarewich CA, Munir AZ, Bezprozvannaya S, Gibson AM, Young Kim S, Martin-Sandoval MS, Mathews TP, Szweda LI, Bassel-Duby R, Olson EN. The cardiac-enriched microprotein mitolamban regulates mitochondrial respiratory complex assembly and function in mice. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35101990 DOI: 10.1073/pnas.2120476119  0.347
2021 Menendez-Montes I, Abdisalaam S, Xiao F, Lam NT, Mukherjee S, Szweda LI, Asaithamby A, Sadek HA. Mitochondrial fatty acid utilization increases chromatin oxidative stress in cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34417314 DOI: 10.1073/pnas.2101674118  0.403
2021 Tong D, Schiattarella GG, Jiang N, Altamirano F, Szweda PA, Elnwasany A, Lee DI, Yoo H, Kass DA, Szweda LI, Lavandero S, Verdin E, Gillette TG, Hill JA. NAD Repletion Reverses Heart Failure with Preserved Ejection Fraction. Circulation Research. PMID 33882692 DOI: 10.1161/CIRCRESAHA.120.317046  0.383
2020 Kim SY, Zhang X, Schiattarella GG, Altamirano F, Ramos TAR, French KM, Jiang N, Szweda PA, Evers BM, May HI, Luo X, Li H, Szweda LI, Maracaja-Coutinho V, Lavandero S, et al. Epigenetic Reader BRD4 Governs Nucleus-encoded Mitochondrial Transcriptome to Regulate Cardiac Function. Circulation. PMID 33113340 DOI: 10.1161/CIRCULATIONAHA.120.047239  0.374
2020 Filipe A, Chernorudskiy A, Arbogast S, Varone E, Villar-Quiles RN, Pozzer D, Moulin M, Fumagalli S, Cabet E, Dudhal S, De Simoni MG, Denis R, Vadrot N, Dill C, Giovarelli M, ... Szweda L, et al. Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy. Cell Death and Differentiation. PMID 32661288 DOI: 10.1038/S41418-020-0587-Z  0.366
2020 Cardoso AC, Lam NT, Savla JJ, Nakada Y, Pereira AHM, Elnwasany A, Menendez-Montes I, Ensley EL, Petric UB, Sharma G, Sherry AD, Malloy CR, Khemtong C, Kinter MT, Tan WLW, ... ... Szweda LI, et al. Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression. Nature Metabolism. 2: 167-178. PMID 32617517  0.359
2019 Newhardt MF, Batushansky A, Matsuzaki S, Young ZT, West M, Chin NC, Szweda LI, Kinter M, Humphries KM. Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short term high fat diet. The Journal of Biological Chemistry. PMID 31562244 DOI: 10.1074/Jbc.Ra119.010371  0.72
2019 Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, ... ... Szweda LI, et al. Evidence for hormonal control of heart regenerative capacity during endothermy acquisition. Science (New York, N.Y.). PMID 30846611 DOI: 10.1126/Science.Aar2038  0.319
2018 Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN. MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation. Cell Reports. 23: 3701-3709. PMID 29949755 DOI: 10.1016/J.Celrep.2018.05.058  0.45
2018 Schafer C, Young ZT, Makarewich CA, Elnwasany A, Kinter CS, Kinter M, Szweda LI. Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice. The Journal of Biological Chemistry. PMID 29540486 DOI: 10.1074/Jbc.Ra117.000268  0.415
2018 Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, et al. Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Molecular Metabolism. PMID 29398615 DOI: 10.1016/J.Molmet.2018.01.013  0.676
2017 Pearsall EA, Cheng R, Zhou K, Takahashi Y, Matlock HG, Vadvalkar SS, Shin Y, Fredrick TW, Gantner ML, Meng S, Fu Z, Gong Y, Kinter M, Humphries KM, Szweda LI, et al. PPARα is essential for retinal lipid metabolism and neuronal survival. Bmc Biology. 15: 113. PMID 29183319 DOI: 10.1186/S12915-017-0451-X  0.642
2016 Crewe C, Schafer C, Lee I, Kinter M, Szweda LI. Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart Through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability. The Journal of Biological Chemistry. PMID 27856638 DOI: 10.1074/Jbc.M116.754127  0.377
2016 Rindler PM, Cacciola A, Kinter M, Szweda LI. Catalase-Dependent H2O2 Consumption by Cardiac Mitochondria and Redox-Mediated Loss in Insulin Signaling. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00066.2016. PMID 27614223 DOI: 10.1152/Ajpheart.00066.2016  0.35
2016 James KL, Ríos-Hernández LA, Wofford NQ, Mouttaki H, Sieber JR, Sheik CS, Nguyen HH, Yang Y, Xie Y, Erde J, Rohlin L, Karr EA, Loo JA, Ogorzalek Loo RR, Hurst GB, ... ... Szweda LI, et al. Pyrophosphate-Dependent ATP Formation from Acetyl Coenzyme A in Syntrophus aciditrophicus, a New Twist on ATP Formation. Mbio. 7. PMID 27531911 DOI: 10.1128/Mbio.01208-16  0.35
2015 Griffin TM, Humphries KM, Kinter M, Lim HY, Szweda LI. Nutrient sensing and utilization: Getting to the heart of metabolic flexibility. Biochimie. PMID 26476002 DOI: 10.1016/J.Biochi.2015.10.013  0.64
2015 Griffith AV, Venables T, Shi J, Farr A, van Remmen H, Szweda L, Fallahi M, Rabinovitch P, Petrie HT. Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency. Cell Reports. 12: 1071-9. PMID 26257169 DOI: 10.1016/J.Celrep.2015.07.008  0.32
2015 Fernandes J, Weddle A, Kinter CS, Humphries KM, Mather T, Szweda LI, Kinter M. Lysine Acetylation Activates Mitochondrial Aconitase in the Heart. Biochemistry. 54: 4008-18. PMID 26061789 DOI: 10.1021/Acs.Biochem.5B00375  0.705
2015 Fernandes J, Weddle A, Kinter CS, Humphries KM, Mather T, Szweda LI, Kinter M. Lysine Acetylation Activates Mitochondrial Aconitase in the Heart Biochemistry. 54: 4008-4018. DOI: 10.1021/acs.biochem.5b00375  0.696
2014 DeBalsi KL, Wong KE, Koves TR, Slentz DH, Seiler SE, Wittmann AH, Ilkayeva OR, Stevens RD, Perry CG, Lark DS, Hui ST, Szweda L, Neufer PD, Muoio DM. Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle. The Journal of Biological Chemistry. 289: 8106-20. PMID 24482226 DOI: 10.1074/Jbc.M113.511535  0.451
2013 Rindler PM, Crewe CL, Fernandes J, Kinter M, Szweda LI. Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria. American Journal of Physiology. Heart and Circulatory Physiology. 305: H634-43. PMID 23792672 DOI: 10.1152/Ajpheart.00799.2012  0.343
2013 Allen BG, Bhatia SK, Buatti JM, Brandt KE, Lindholm KE, Button AM, Szweda LI, Smith BJ, Spitz DR, Fath MA. Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3905-13. PMID 23743570 DOI: 10.1158/1078-0432.Ccr-12-0287  0.359
2013 McLain AL, Cormier PJ, Kinter M, Szweda LI. Glutathionylation of α-ketoglutarate dehydrogenase: the chemical nature and relative susceptibility of the cofactor lipoic acid to modification. Free Radical Biology & Medicine. 61: 161-9. PMID 23567190 DOI: 10.1016/J.Freeradbiomed.2013.03.020  0.33
2013 Rindler PM, Plafker SM, Szweda LI, Kinter M. High dietary fat selectively increases catalase expression within cardiac mitochondria. The Journal of Biological Chemistry. 288: 1979-90. PMID 23204527 DOI: 10.1074/Jbc.M112.412890  0.466
2012 Plafker SM, O'Mealey GB, Szweda LI. Mechanisms for countering oxidative stress and damage in retinal pigment epithelium. International Review of Cell and Molecular Biology. 298: 135-77. PMID 22878106 DOI: 10.1016/B978-0-12-394309-5.00004-3  0.32
2012 Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/J.Freeradbiomed.2011.11.004  0.336
2011 Dasuri K, Zhang L, Ebenezer P, Fernandez-Kim SO, Bruce-Keller AJ, Szweda LI, Keller JN. Proteasome alterations during adipose differentiation and aging: links to impaired adipocyte differentiation and development of oxidative stress. Free Radical Biology & Medicine. 51: 1727-35. PMID 21871954 DOI: 10.1016/J.Freeradbiomed.2011.08.001  0.318
2011 McLain AL, Szweda PA, Szweda LI. α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor. Free Radical Research. 45: 29-36. PMID 21110783 DOI: 10.3109/10715762.2010.534163  0.383
2011 McLain AL, Humphries KM, Stofan D, Kinter MT, Szweda LI. Inactivation of α-Ketoglutarate Dehydrogenase by 4Hydroxy-2-nonenal; Modification and Metabolic Fate of the Cofactor Lipoic Acid Free Radical Biology and Medicine. 51. DOI: 10.1016/J.Freeradbiomed.2011.10.073  0.642
2010 Cussiol JR, Alegria TG, Szweda LI, Netto LE. Ohr (organic hydroperoxide resistance protein) possesses a previously undescribed activity, lipoyl-dependent peroxidase. The Journal of Biological Chemistry. 285: 21943-50. PMID 20463026 DOI: 10.1074/Jbc.M110.117283  0.319
2010 Churchill EN, Ferreira JC, Brum PC, Szweda LI, Mochly-Rosen D. Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. Cardiovascular Research. 85: 385-94. PMID 19820255 DOI: 10.1093/Cvr/Cvp334  0.743
2010 Castellani R, Moreira P, Aliev G, Shenk J, Siedlak S, Harris P, Sayre L, Szweda L, Zhu X, Smith M, Perry G, Szweda P. Hydroxynonenal-Generated Crosslinking Fluorophore and Mitochondria-derived Lipoic Acid Accumulation in Alzheimer Disease Reveal a Dichotomy of Protein Turnover Microscopy and Microanalysis. 16: 1014-1015. DOI: 10.1017/S1431927610059350  0.319
2010 Rindler PM, Szweda LI, Kinter M. High-fat Diet Induced Cardiac Oxidative Stress Differentially Modulates Protein Expression and Specific Activity of the Antioxidant Enzyme Catalase Free Radical Biology and Medicine. 49. DOI: 10.1016/J.Freeradbiomed.2010.10.563  0.371
2009 Matsuzaki S, Szweda PA, Szweda LI, Humphries KM. Regulated production of free radicals by the mitochondrial electron transport chain: Cardiac ischemic preconditioning. Advanced Drug Delivery Reviews. 61: 1324-31. PMID 19716389 DOI: 10.1016/J.Addr.2009.05.008  0.716
2009 Matsuzaki S, Szweda LI, Humphries KM. Mitochondrial superoxide production and respiratory activity: biphasic response to ischemic duration. Archives of Biochemistry and Biophysics. 484: 87-93. PMID 19467633 DOI: 10.1016/J.Abb.2009.01.006  0.715
2009 Wu M, Chen Y, Wilson K, Boulton ME, Applegate M, Ma JX, Szweda L, Lyons TJ. Mechanisms of oxidized and glycated LDL induced human retinal capillary pericyte loss: oxidative stress, proteasome inhibition and mitochondrial-mediated apoptosis Canadian Journal of Diabetes. 33: 223. DOI: 10.1016/S1499-2671(09)33103-2  0.399
2008 Zhang SX, Wang JJ, Dashti A, Wilson K, Zou MH, Szweda L, Ma JX, Lyons TJ. Pigment epithelium-derived factor mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized low-density lipoprotein. Journal of Molecular Endocrinology. 41: 135-43. PMID 18586837 DOI: 10.1677/Jme-08-0011  0.347
2008 Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, Garry DJ. Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells. Circulation Research. 102: 1075-81. PMID 18356544 DOI: 10.1161/Circresaha.107.161729  0.332
2008 Applegate MA, Humphries KM, Szweda LI. Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid. Biochemistry. 47: 473-8. PMID 18081316 DOI: 10.1021/Bi7017464  0.718
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 3: 614-5. PMID 17786024 DOI: 10.4161/Auto.4872  0.412
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 66: 525-32. PMID 17549012 DOI: 10.1016/J.Jns.2009.02.162  0.421
2007 Oktay Y, Dioum E, Matsuzaki S, Ding K, Yan LJ, Haller RG, Szweda LI, Garcia JA. Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin. The Journal of Biological Chemistry. 282: 11750-6. PMID 17322295 DOI: 10.1074/Jbc.M611133200  0.469
2007 Perry G, Moreira PI, Siedlak SL, Santos MS, Oliveira CR, Fujioka H, Tabaton M, Nunomura A, Aliev G, Szweda LI, Smith MA. Mitochondrial autophagocytosis in Alzheimer disease Journal of Neuropathology and Experimental Neurology. 66: 434. DOI: 10.1097/01.Jnen.0000268871.37441.1B  0.373
2006 Humphries KM, Szweda PA, Szweda LI. Aging: a shift from redox regulation to oxidative damage. Free Radical Research. 40: 1239-43. PMID 17090412 DOI: 10.1080/10715760600913184  0.681
2006 Haynes RL, Folkerth RD, Szweda LI, Volpe JJ, Kinney HC. Lipid peroxidation during human cerebral myelination. Journal of Neuropathology and Experimental Neurology. 65: 894-904. PMID 16957583 DOI: 10.1097/01.Jnen.0000235858.56631.97  0.321
2006 Bulteau AL, Szweda LI, Friguet B. Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Experimental Gerontology. 41: 653-7. PMID 16677792 DOI: 10.1016/J.Exger.2006.03.013  0.461
2006 Picot CR, Perichon M, Lundberg KC, Friguet B, Szweda LI, Petropoulos I. Alterations in mitochondrial and cytosolic methionine sulfoxide reductase activity during cardiac ischemia and reperfusion. Experimental Gerontology. 41: 663-7. PMID 16677789 DOI: 10.1016/J.Exger.2006.03.011  0.522
2006 Lundberg KC, Szweda LI. Preconditioning prevents loss in mitochondrial function and release of cytochrome c during prolonged cardiac ischemia/reperfusion. Archives of Biochemistry and Biophysics. 453: 130-4. PMID 16546113 DOI: 10.1016/J.Abb.2006.02.007  0.516
2006 Farout L, Mary J, Vinh J, Szweda LI, Friguet B. Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes. Archives of Biochemistry and Biophysics. 453: 135-42. PMID 16530722 DOI: 10.1016/J.Abb.2006.02.003  0.435
2006 Lashin OM, Szweda PA, Szweda LI, Romani AM. Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart. Free Radical Biology & Medicine. 40: 886-96. PMID 16520240 DOI: 10.1016/j.freeradbiomed.2005.10.040  0.323
2006 Moreira PI, Siedlak SL, Santos MS, Oliveira CR, Fujioka H, Tabaton M, Nunomura A, Aliev G, Szweda LI, Zhu X, Smith MA, Perry G. O4-02-08: Mitochondrial autophagocytosis in Alzheimer disease Alzheimer's & Dementia. 2: S79-S79. DOI: 10.1016/J.Jalz.2006.05.307  0.383
2005 Chaiswing L, Cole MP, Ittarat W, Szweda LI, St Clair DK, Oberley TD. Manganese superoxide dismutase and inducible nitric oxide synthase modify early oxidative events in acute adriamycin-induced mitochondrial toxicity. Molecular Cancer Therapeutics. 4: 1056-64. PMID 16020663 DOI: 10.1158/1535-7163.MCT-04-0322  0.329
2005 Churchill EN, Szweda LI. Translocation of deltaPKC to mitochondria during cardiac reperfusion enhances superoxide anion production and induces loss in mitochondrial function. Archives of Biochemistry and Biophysics. 439: 194-9. PMID 15963450 DOI: 10.1016/J.Abb.2005.05.007  0.78
2005 Churchill EN, Murriel CL, Chen CH, Mochly-Rosen D, Szweda LI. Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation. Circulation Research. 97: 78-85. PMID 15961716 DOI: 10.1161/01.Res.0000173896.32522.6E  0.769
2005 Mason KE, Stofan DA, Szweda LI. Inhibition of very long chain acyl-CoA dehydrogenase during cardiac ischemia. Archives of Biochemistry and Biophysics. 437: 138-43. PMID 15850553 DOI: 10.1016/j.abb.2005.03.004  0.439
2005 Bulteau AL, Lundberg KC, Ikeda-Saito M, Isaya G, Szweda LI. Reversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusion. Proceedings of the National Academy of Sciences of the United States of America. 102: 5987-91. PMID 15840721 DOI: 10.1073/Pnas.0501519102  0.454
2005 Rosca MG, Mustata TG, Kinter MT, Ozdemir AM, Kern TS, Szweda LI, Brownlee M, Monnier VM, Weiss MF. Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. American Journal of Physiology. Renal Physiology. 289: F420-30. PMID 15814529 DOI: 10.1152/Ajprenal.00415.2004  0.314
2004 Chaiswing L, Cole MP, St Clair DK, Ittarat W, Szweda LI, Oberley TD. Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury. Toxicologic Pathology. 32: 536-47. PMID 15605432 DOI: 10.1080/01926230490502601  0.337
2004 Lundberg KC, Szweda LI. Initiation of mitochondrial-mediated apoptosis during cardiac reperfusion. Archives of Biochemistry and Biophysics. 432: 50-7. PMID 15519296 DOI: 10.1016/j.abb.2004.08.025  0.362
2004 Nulton-Persson AC, Szweda LI, Sadek HA. Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate. Journal of Cardiovascular Pharmacology. 44: 591-5. PMID 15505497 DOI: 10.1097/00005344-200411000-00012  0.777
2004 Murriel CL, Churchill E, Inagaki K, Szweda LI, Mochly-Rosen D. Protein kinase Cdelta activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria. The Journal of Biological Chemistry. 279: 47985-91. PMID 15339931 DOI: 10.1074/Jbc.M405071200  0.748
2004 Marques C, Pereira P, Taylor A, Liang JN, Reddy VN, Szweda LI, Shang F. Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1424-6. PMID 15247152 DOI: 10.1096/Fj.04-1743Fje  0.328
2004 Sadek HA, Szweda PA, Szweda LI. Modulation of mitochondrial complex I activity by reversible Ca2+ and NADH mediated superoxide anion dependent inhibition. Biochemistry. 43: 8494-502. PMID 15222760 DOI: 10.1021/Bi049803F  0.339
2004 Oberley TD, Xue Y, Zhao Y, Kiningham K, Szweda LI, St Clair DK. In situ reduction of oxidative damage, increased cell turnover, and delay of mitochondrial injury by overexpression of manganese superoxide dismutase in a multistage skin carcinogenesis model. Antioxidants & Redox Signaling. 6: 537-48. PMID 15130280 DOI: 10.1089/152308604773934297  0.3
2003 Bulteau AL, Ikeda-Saito M, Szweda LI. Redox-dependent modulation of aconitase activity in intact mitochondria. Biochemistry. 42: 14846-55. PMID 14674759 DOI: 10.1021/Bi0353979  0.422
2003 Sadek HA, Nulton-Persson AC, Szweda PA, Szweda LI. Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function. Archives of Biochemistry and Biophysics. 420: 201-8. PMID 14654058 DOI: 10.1016/J.Abb.2003.09.029  0.775
2003 Czerski LW, Szweda PA, Szweda LI. Dissociation of cytochrome c from the inner mitochondrial membrane during cardiac ischemia. The Journal of Biological Chemistry. 278: 34499-504. PMID 12813053 DOI: 10.1074/jbc.M302021200  0.303
2003 Nulton-Persson AC, Starke DW, Mieyal JJ, Szweda LI. Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry. 42: 4235-42. PMID 12680778 DOI: 10.1021/Bi027370F  0.783
2003 Lucas DT, Aryal P, Szweda LI, Koch WJ, Leinwand LA. Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 284: H575-83. PMID 12414446 DOI: 10.1152/Ajpheart.00619.2002  0.352
2002 Sadek HA, Humphries KM, Szweda PA, Szweda LI. Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion. Archives of Biochemistry and Biophysics. 406: 222-8. PMID 12361710 DOI: 10.1016/S0003-9861(02)00446-0  0.735
2001 Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI. Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. The Journal of Biological Chemistry. 276: 30057-63. PMID 11375979 DOI: 10.1074/Jbc.M100142200  0.689
2001 Lauderback CM, Hackett JM, Keller JN, Varadarajan S, Szweda L, Kindy M, Markesbery WR, Butterfield DA. Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease. Biochemistry. 40: 2548-54. PMID 11327877 DOI: 10.1021/Bi002312K  0.301
2001 Nulton-Persson AC, Szweda LI. Modulation of mitochondrial function by hydrogen peroxide. The Journal of Biological Chemistry. 276: 23357-61. PMID 11283020 DOI: 10.1074/Jbc.M100320200  0.759
2001 Callahan LA, Stofan DA, Szweda LI, Nethery DE, Supinski GS. Free radicals alter maximal diaphragmatic mitochondrial oxygen consumption in endotoxin-induced sepsis. Free Radical Biology & Medicine. 30: 129-38. PMID 11134903 DOI: 10.1016/S0891-5849(00)00454-8  0.345
2000 Haynes RL, Szweda L, Pickin K, Welker ME, Townsend AJ. Structure-activity relationships for growth inhibition and induction of apoptosis by 4-hydroxy-2-nonenal in raw 264.7 cells. Molecular Pharmacology. 58: 788-94. PMID 10999949 DOI: 10.1124/Mol.58.4.788  0.319
2000 Zainal TA, Oberley TD, Allison DB, Szweda LI, Weindruch R. Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle Faseb Journal. 14: 1825-1836. PMID 10973932 DOI: 10.1096/Fj.99-0881Com  0.315
2000 Sasaki M, Ansari A, Pumford N, van de Water J, Leung PS, Humphries KM, Szweda LI, Nakanuma Y, Roche TE, Coppel RL, Bach JF, Gershwin ME. Comparative immunoreactivity of anti-trifluoroacetyl (TFA) antibody and anti-lipoic acid antibody in primary biliary cirrhosis: searching for a mimic. Journal of Autoimmunity. 15: 51-60. PMID 10936028 DOI: 10.1006/Jaut.2000.0390  0.599
1999 Lucas DT, Szweda LI. Declines in mitochondrial respiration during cardiac reperfusion: Age-dependent inactivation of α-ketoglutarate dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 96: 6689-6693. PMID 10359773  0.433
1999 Yen HC, Oberley TD, Gairola CG, Szweda LI, St. Clair DK. Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice Archives of Biochemistry and Biophysics. 362: 59-66. PMID 9917329 DOI: 10.1006/abbi.1998.1011  0.323
1998 Humphries KM, Szweda LI. Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal. Biochemistry. 37: 15835-41. PMID 9843389 DOI: 10.1021/Bi981512H  0.746
1998 Tsai L, Szweda PA, Vinogradova O, Szweda LI. Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine Proceedings of the National Academy of Sciences of the United States of America. 95: 7975-7980. PMID 9653125 DOI: 10.1073/Pnas.95.14.7975  0.318
1998 Majima HJ, Oberley TD, Furukawa K, Mattson MP, Yen HC, Szweda LI, St. Clair DK. Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death Journal of Biological Chemistry. 273: 8217-8224. PMID 9525927 DOI: 10.1074/jbc.273.14.8217  0.334
1998 Lucas DT, Szweda LI. Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction Proceedings of the National Academy of Sciences of the United States of America. 95: 510-514. PMID 9435222 DOI: 10.1073/pnas.95.2.510  0.426
1998 Humphries KM, Yoo Y, Szweda LI. Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal. Biochemistry. 37: 552-7. PMID 9425076 DOI: 10.1021/Bi971958I  0.758
1997 Humphries KM, Szweda LI. 4-hydroxy-2-nonenal mediated declines in mitochondrial respiration Faseb Journal. 11.  0.732
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