| Year |
Citation |
Score |
| 2023 |
Shiota T, Li Z, Chen GY, McKnight KL, Shirasaki T, Yonish B, Kim H, Fritch EJ, Sheahan TP, Muramatsu M, Kapustina M, Cameron CE, Li Y, Zhang Q, Lemon SM. Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release. Science Advances. 9: eadj4198. PMID 37862421 DOI: 10.1126/sciadv.adj4198 |
0.375 |
|
| 2023 |
Kim H, Aponte-Diaz D, Sotoudegan MS, Shengjuler D, Arnold JJ, Cameron CE. The enterovirus genome can be translated in an IRES-independent manner that requires the initiation factors eIF2A/eIF2D. Plos Biology. 21: e3001693. PMID 36689548 DOI: 10.1371/journal.pbio.3001693 |
0.421 |
|
| 2022 |
Chinthapatla R, Sotoudegan M, Srivastava P, Anderson TK, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer RN, Cameron CE, Arnold JJ. Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease. Nucleic Acids Research. PMID 36546762 DOI: 10.1093/nar/gkac1177 |
0.45 |
|
| 2022 |
Yeager C, Carter G, Gohara DW, Yennawar NH, Enemark EJ, Arnold JJ, Cameron CE. Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP. Nucleic Acids Research. 50: 11775-11798. PMID 36399514 DOI: 10.1093/nar/gkac1054 |
0.367 |
|
| 2022 |
Chinthapatla R, Sotoudegan M, Anderson T, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer R, Cameron CE, Arnold JJ. Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease. Biorxiv : the Preprint Server For Biology. PMID 35982684 DOI: 10.1101/2022.08.11.503614 |
0.45 |
|
| 2022 |
Li Y, Misumi I, Shiota T, Sun L, Lenarcic EM, Kim H, Shirasaki T, Hertel-Wulff A, Tibbs T, Mitchell JE, McKnight KL, Cameron CE, Moorman NJ, McGivern DR, Cullen JM, et al. The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2204511119. PMID 35867748 DOI: 10.1073/pnas.2204511119 |
0.47 |
|
| 2022 |
Jiang Y, Hoenisch RC, Chang Y, Bao X, Cameron CE, Lian XL. Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems. Bioactive Materials. 14: 313-320. PMID 35386818 DOI: 10.1016/j.bioactmat.2022.01.046 |
0.345 |
|
| 2021 |
Wang N, Wang H, Shi J, Li C, Liu X, Fan J, Sun C, Cameron CE, Qi H, Yu L. The Stem-Loop I of Senecavirus A IRES Is Essential for Cap-Independent Translation Activity and Virus Recovery. Viruses. 13. PMID 34834966 DOI: 10.3390/v13112159 |
0.342 |
|
| 2021 |
Janissen R, Woodman A, Shengjuler D, Vallet T, Lee KM, Kuijpers L, Moustafa IM, Fitzgerald F, Huang PN, Perkins AL, Harki DA, Arnold JJ, Solano B, Shih SR, Vignuzzi M, ... Cameron CE, et al. Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses. Molecular Cell. PMID 34687604 DOI: 10.1016/j.molcel.2021.10.003 |
0.499 |
|
| 2021 |
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo S, Grove TL, Shi PY, ... ... Cameron CE, et al. Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective. Elife. 10. PMID 34617885 DOI: 10.7554/eLife.70968 |
0.374 |
|
| 2021 |
Bera SC, Seifert M, Kirchdoerfer RN, van Nies P, Wubulikasimu Y, Quack S, Papini FS, Arnold JJ, Canard B, Cameron CE, Depken M, Dulin D. The nucleotide addition cycle of the SARS-CoV-2 polymerase. Cell Reports. 109650. PMID 34433083 DOI: 10.1016/j.celrep.2021.109650 |
0.423 |
|
| 2021 |
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo SC, Grove TL, Shi PY, ... ... Cameron CE, et al. Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective. Biorxiv : the Preprint Server For Biology. PMID 33851161 DOI: 10.1101/2020.08.06.240325 |
0.426 |
|
| 2021 |
Bera SC, Seifert M, Kirchdoerfer RN, van Nies P, Wubulikasimu Y, Quack S, Papini FS, Arnold JJ, Canard B, Cameron CE, Depken M, Dulin D. The nucleotide addition cycle of the SARS-CoV-2 polymerase. Biorxiv : the Preprint Server For Biology. PMID 33791706 DOI: 10.1101/2021.03.27.437309 |
0.366 |
|
| 2020 |
Li C, Shi J, Wang H, Rivera-Serrano EE, Yang D, Zhou G, Sun C, Cameron CE, Yu L. Polymerase fidelity contributes to foot-and-mouth disease virus pathogenicity and transmissibility . Journal of Virology. PMID 33028719 DOI: 10.1128/JVI.01569-20 |
0.339 |
|
| 2020 |
Rivera-Serrano EE, Gizzi AS, Arnold JJ, Grove TL, Almo SC, Cameron CE. Viperin Reveals Its True Function. Annual Review of Virology. PMID 32603630 DOI: 10.1146/annurev-virology-011720-095930 |
0.452 |
|
| 2020 |
Seifert M, van Nies P, Papini FS, Arnold JJ, Poranen MM, Cameron CE, Depken M, Dulin D. Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases. Nucleic Acids Research. PMID 32286652 DOI: 10.1093/Nar/Gkaa233 |
0.458 |
|
| 2019 |
Guo L, Sharma SD, Debes JD, Beisang D, Rattenbacher B, Louis IV, Wiesner DL, Cameron CE, Bohjanen PR. The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts. Nucleic Acids Research. PMID 31863579 DOI: 10.1093/Nar/Gkz1211 |
0.322 |
|
| 2019 |
Kim H, Ellis VD, Woodman A, Zhao Y, Arnold JJ, Cameron CE. RNA-Dependent RNA Polymerase Speed and Fidelity are not the Only Determinants of the Mechanism or Efficiency of Recombination. Genes. 10. PMID 31775299 DOI: 10.3390/Genes10120968 |
0.565 |
|
| 2019 |
Liu W, Caglar MU, Mao Z, Woodman A, Arnold JJ, Wilke CO, Cameron CE. More than efficacy revealed by single-cell analysis of antiviral therapeutics. Science Advances. 5: eaax4761. PMID 31692968 DOI: 10.1126/Sciadv.Aax4761 |
0.331 |
|
| 2019 |
Boehr AK, Arnold JJ, Oh HS, Cameron CE, Boehr DD. 2'-C-Methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase. The Journal of Biological Chemistry. PMID 31575662 DOI: 10.1074/Jbc.Ra119.010214 |
0.557 |
|
| 2019 |
Shi J, Perryman JM, Yang X, Liu X, Musser DM, Boehr AK, Moustafa IM, Arnold JJ, Cameron CE, Boehr DD. Rational control of poliovirus RNA-dependent RNA polymerase fidelity by modulating motif D loop conformational dynamics. Biochemistry. PMID 31424194 DOI: 10.1021/Acs.Biochem.9B00497 |
0.487 |
|
| 2019 |
Li C, Wang H, Shi J, Yang D, Zhou G, Chang J, Cameron CE, Woodman A, Yu L. Senecavirus-Specific Recombination Assays Reveal the Intimate Link between Polymerase Fidelity and RNA Recombination. Journal of Virology. PMID 30996084 DOI: 10.1128/Jvi.00576-19 |
0.584 |
|
| 2018 |
Woodman A, Lee KM, Janissen R, Gong YN, Dekker N, Shih SR, Cameron CE. Predicting Intraserotypic Recombination in Enterovirus 71. Journal of Virology. PMID 30487277 DOI: 10.1128/Jvi.02057-18 |
0.432 |
|
| 2018 |
Fitzsimmons WJ, Woods RJ, McCrone JT, Woodman A, Arnold JJ, Yennawar M, Evans R, Cameron CE, Lauring AS. A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus. Plos Biology. 16: e2006459. PMID 29953453 DOI: 10.1371/Journal.Pbio.2006459 |
0.491 |
|
| 2018 |
Lee KM, Gong YN, Hsieh TH, Woodman A, Dekker NH, Cameron CE, Shih SR. Discovery of Enterovirus A71-like nonstructural genomes in recent circulating viruses of the Enterovirus A species. Emerging Microbes & Infections. 7: 111. PMID 29930332 DOI: 10.1038/S41426-018-0107-0 |
0.312 |
|
| 2018 |
Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD, Chandran K, Bresnick AR, Cameron CE, Almo SC. A naturally occurring antiviral ribonucleotide encoded by the human genome. Nature. PMID 29925952 DOI: 10.1038/S41586-018-0238-4 |
0.559 |
|
| 2018 |
Banerjee S, Aponte-Diaz D, Yeager C, Sharma SD, Ning G, Oh HS, Han Q, Umeda M, Hara Y, Wang RYL, Cameron CE. Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. Plos Pathogens. 14: e1007086. PMID 29782554 DOI: 10.1371/Journal.Ppat.1007086 |
0.345 |
|
| 2018 |
Oh HS, Banerjee S, Aponte-Diaz D, Sharma SD, Aligo J, Lodeiro MF, Ning G, Sharma R, Arnold JJ, Cameron CE. Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides. Plos Pathogens. 14: e1007036. PMID 29702686 DOI: 10.1371/Journal.Ppat.1007036 |
0.787 |
|
| 2018 |
Li C, Wang H, Yuan T, Woodman A, Yang D, Zhou G, Cameron CE, Yu L. Foot-and-mouth disease virus type O specific mutations determine RNA-dependent RNA polymerase fidelity and virus attenuation. Virology. 518: 87-94. PMID 29455065 DOI: 10.1016/J.Virol.2018.01.030 |
0.396 |
|
| 2018 |
Guo L, Sharma SD, Debes J, Beisang D, Rattenbacher B, Louis IV, Wiesner DL, Cameron CE, Bohjanen PR. The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts. Nucleic Acids Research. PMID 29385522 DOI: 10.1093/Nar/Gky061 |
0.409 |
|
| 2017 |
Shengjuler D, Chan YM, Sun S, Moustafa IM, Li ZL, Gohara DW, Buck M, Cremer PS, Boehr DD, Cameron CE. The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain. Structure (London, England : 1993). 25: 1875-1886.e7. PMID 29211985 DOI: 10.1016/J.Str.2017.11.001 |
0.429 |
|
| 2017 |
Guo F, Li S, Caglar MU, Mao Z, Liu W, Woodman A, Arnold JJ, Wilke CO, Huang TJ, Cameron CE. Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics. Cell Reports. 21: 1692-1704. PMID 29117571 DOI: 10.1016/J.Celrep.2017.10.051 |
0.382 |
|
| 2017 |
Dulin D, Arnold JJ, van Laar T, Oh HS, Lee C, Perkins AL, Harki DA, Depken M, Cameron CE, Dekker NH. Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers. Cell Reports. 21: 1063-1076. PMID 29069588 DOI: 10.1016/J.Celrep.2017.10.005 |
0.561 |
|
| 2017 |
Uchida A, Murugesapillai D, Kastner M, Wang Y, Lodeiro MF, Prabhakar S, Oliver GV, Arnold JJ, Maher LJ, Williams MC, Cameron CE. Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter. Elife. 6. PMID 28745586 DOI: 10.7554/Elife.27283 |
0.307 |
|
| 2017 |
Huang PN, Jheng JR, Arnold JJ, Wang JR, Cameron CE, Shih SR. UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication. Plos Pathogens. 13: e1006375. PMID 28545059 DOI: 10.1371/Journal.Ppat.1006375 |
0.52 |
|
| 2017 |
Griesemer SB, Kramer LD, Van Slyke GA, Pata JD, Gohara DW, Cameron CE, Ciota AT. Mutagen resistance and mutation restriction of St. Louis encephalitis virus. The Journal of General Virology. 98: 201-211. PMID 28284278 DOI: 10.1099/Jgv.0.000682 |
0.589 |
|
| 2017 |
Yang X, Liu X, Musser DM, Moustafa IM, Arnold JJ, Cameron CE, Boehr DD. Triphosphate Re-orientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA polymerases. The Journal of Biological Chemistry. PMID 28100782 DOI: 10.1074/Jbc.M116.750638 |
0.532 |
|
| 2016 |
Griesemer SB, Kramer LD, Van Slyke GA, Pata JD, Gohara DD, Cameron CE, Ciota AT. Mutagen resistance and mutation restriction of St. Louis encephalitis virus. The Journal of General Virology. PMID 27959789 DOI: 10.1099/jgv.0.000682 |
0.5 |
|
| 2016 |
Baumgart BR, Wang F, Kwagh J, Storck C, Euler C, Fuller M, Simic D, Sharma S, Arnold JJ, Cameron CE, Van Vleet TR, Flint O, Bunch RT, Davies MH, Graziano MJ, et al. Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27466212 DOI: 10.1093/Toxsci/Kfw135 |
0.305 |
|
| 2016 |
Woodman A, Arnold JJ, Cameron CE, Evans DJ. Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination. Nucleic Acids Research. PMID 27317698 DOI: 10.1093/Nar/Gkw567 |
0.517 |
|
| 2016 |
Chan YM, Moustafa IM, Arnold JJ, Cameron CE, Boehr DD. Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein. Structure (London, England : 1993). 24: 509-17. PMID 27050688 DOI: 10.1016/J.Str.2016.02.019 |
0.497 |
|
| 2016 |
Gajewski JP, Arnold JJ, Salminen TS, Kaguni LS, Cameron CE. Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster. Methods in Molecular Biology (Clifton, N.J.). 1351: 199-210. PMID 26530684 DOI: 10.1007/978-1-4939-3040-1_15 |
0.321 |
|
| 2016 |
Lee CA, August A, Arnold JJ, Cameron CE. Polymerase Mechanism-Based Method of Viral Attenuation. Methods in Molecular Biology (Clifton, N.J.). 1349: 83-104. PMID 26458831 DOI: 10.1007/978-1-4939-3008-1_6 |
0.41 |
|
| 2016 |
Taylor A, Adams C, Zhang X, Gennaro V, Cotney J, Shadel G, Cameron C, Eischen C, McMahon S. Abstract 1256: Multi-focal control of mitochondrial gene expression by oncogenic MYC provides effective therapeutic targets in cancer Cancer Research. 76: 1256-1256. DOI: 10.1158/1538-7445.Am2016-1256 |
0.307 |
|
| 2016 |
Murugesapillai D, Lodeiro MF, Maher LJ, Cameron CE, Williams MC. TFAM Regulates Mitochondrial Transcription through Sequence-Specific DNA Looping Biophysical Journal. 110: 516a. DOI: 10.1016/J.Bpj.2015.11.2756 |
0.307 |
|
| 2016 |
Cameron CE, Moustafa IM, Arnold JJ. Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus Enzymes. 39: 293-323. DOI: 10.1016/Bs.Enz.2016.02.002 |
0.512 |
|
| 2015 |
Moustafa IM, Gohara DW, Uchida A, Yennawar N, Cameron CE. Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome? Viruses. 7: 5962-86. PMID 26610545 DOI: 10.3390/V7112919 |
0.424 |
|
| 2015 |
Liu X, Musser DM, Lee CA, Yang X, Arnold JJ, Cameron CE, Boehr DD. Nucleobase but not Sugar Fidelity is Maintained in the Sabin I RNA-Dependent RNA Polymerase. Viruses. 7: 5571-5586. PMID 26516899 DOI: 10.3390/V7102894 |
0.528 |
|
| 2015 |
Van Slyke GA, Arnold JJ, Lugo AJ, Griesemer SB, Moustafa IM, Kramer LD, Cameron CE, Ciota AT. Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes. Plos Pathogens. 11: e1005009. PMID 26114757 DOI: 10.1371/Journal.Ppat.1005009 |
0.505 |
|
| 2015 |
Reynolds KA, Cameron CE, Raney KD. Melting of Duplex DNA in the Absence of ATP by the NS3 Helicase Domain through Specific Interaction with a Single-Strand/Double-Strand Junction. Biochemistry. 54: 4248-58. PMID 26091150 DOI: 10.1021/Acs.Biochem.5B00214 |
0.403 |
|
| 2015 |
Moustafa IM, Uchida A, Wang Y, Yennawar N, Cameron CE. Structural models of mammalian mitochondrial transcription factor B2. Biochimica Et Biophysica Acta. 1849: 987-1002. PMID 26066983 DOI: 10.1016/J.Bbagrm.2015.05.010 |
0.408 |
|
| 2015 |
van der Linden L, Vives-Adrián L, Selisko B, Ferrer-Orta C, Liu X, Lanke K, Ulferts R, De Palma AM, Tanchis F, Goris N, Lefebvre D, De Clercq K, Leyssen P, Lacroix C, Pürstinger G, ... ... Cameron CE, et al. The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family. Plos Pathogens. 11: e1004733. PMID 25799064 DOI: 10.1371/Journal.Ppat.1004733 |
0.532 |
|
| 2015 |
Kolli S, Meng X, Wu X, Shengjuler D, Cameron CE, Xiang Y, Deng J. Structure-function analysis of vaccinia virus H7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication. Journal of Virology. 89: 2209-19. PMID 25473060 DOI: 10.1128/Jvi.03073-14 |
0.369 |
|
| 2015 |
Taylor A, Zhang X, Cotney J, Shadel G, Cameron C, McMahon S. Abstract A05: The mitochondrial RNA polymerase is an essential downstream effector of the MYC oncoprotein Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A05 |
0.361 |
|
| 2014 |
Holien JK, Gazina EV, Elliott RW, Jarrott B, Cameron CE, Williams SJ, Parker MW, Petrou S. Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase. Journal of Proteomics & Bioinformatics. 004. PMID 26491236 DOI: 10.4172/Jpb.S9-004 |
0.418 |
|
| 2014 |
Moustafa IM, Korboukh VK, Arnold JJ, Smidansky ED, Marcotte LL, Gohara DW, Yang X, Sánchez-Farrán MA, Filman D, Maranas JK, Boehr DD, Hogle JM, Colina CM, Cameron CE. Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 289: 36229-48. PMID 25378410 DOI: 10.1074/Jbc.M114.616193 |
0.493 |
|
| 2014 |
Zafar MK, Ketkar A, Lodeiro MF, Cameron CE, Eoff RL. Kinetic analysis of human PrimPol DNA polymerase activity reveals a generally error-prone enzyme capable of accurately bypassing 7,8-dihydro-8-oxo-2'-deoxyguanosine. Biochemistry. 53: 6584-94. PMID 25255211 DOI: 10.1021/Bi501024U |
0.355 |
|
| 2014 |
Korboukh VK, Lee CA, Acevedo A, Vignuzzi M, Xiao Y, Arnold JJ, Hemperly S, Graci JD, August A, Andino R, Cameron CE. RNA virus population diversity, an optimum for maximal fitness and virulence. The Journal of Biological Chemistry. 289: 29531-44. PMID 25213864 DOI: 10.1074/Jbc.M114.592303 |
0.809 |
|
| 2014 |
Cordek DG, Croom-Perez TJ, Hwang J, Hargittai MR, Subba-Reddy CV, Han Q, Lodeiro MF, Ning G, McCrory TS, Arnold JJ, Koc H, Lindenbach BD, Showalter SA, Cameron CE. Expanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein. The Journal of Biological Chemistry. 289: 24397-416. PMID 25031324 DOI: 10.1074/Jbc.M114.589911 |
0.64 |
|
| 2014 |
Liu YC, Kuo RL, Lin JY, Huang PN, Huang Y, Liu H, Arnold JJ, Chen SJ, Wang RY, Cameron CE, Shih SR. Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8. Plos Pathogens. 10: e1004199. PMID 24968230 DOI: 10.1371/Journal.Ppat.1004199 |
0.513 |
|
| 2014 |
Alphonse S, Arnold JJ, Bhattacharya S, Wang H, Kloss B, Cameron CE, Ghose R. Cystoviral polymerase complex protein P7 uses its acidic C-terminal tail to regulate the RNA-directed RNA polymerase P2. Journal of Molecular Biology. 426: 2580-93. PMID 24813120 DOI: 10.1016/J.Jmb.2014.04.028 |
0.45 |
|
| 2013 |
Liu X, Yang X, Lee CA, Moustafa IM, Smidansky ED, Lum D, Arnold JJ, Cameron CE, Boehr DD. Vaccine-derived mutation in motif D of poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporation fidelity. The Journal of Biological Chemistry. 288: 32753-65. PMID 24085299 DOI: 10.1074/Jbc.M113.484428 |
0.493 |
|
| 2013 |
Nallagatla SR, Jones CN, Ghosh SK, Sharma SD, Cameron CE, Spremulli LL, Bevilacqua PC. Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR. Plos One. 8: e57905. PMID 23483938 DOI: 10.1371/Journal.Pone.0057905 |
0.47 |
|
| 2013 |
Arnold JJ, Oh H, Banerjee S, Lodeiro MF, Han Q, Shengjuler D, Uchida A, Moustafa IM, Moran J, Hsu N, Mei Chan Y, Altan-Bonnet N, Boehr DD, Cameron CE. On the Role of Protein 3CD in Formation of the Poliovirus Replication Organelle Biophysical Journal. 104: 96a. DOI: 10.1016/J.Bpj.2012.11.571 |
0.428 |
|
| 2013 |
Moustafa IM, Korneeva VS, Arnold JJ, Smidansky ED, Marcotte LL, Yang X, Sanchez Farran MA, Maranas JK, Boehr DD, Hogle JM, Colina CM, Cameron CE. Nanosecond-Timescale Dynamics of the Viral RNA-Dependent RNA Polymerase as a Determinant of Incorporation Fidelity Biophysical Journal. 104: 213a. DOI: 10.1016/J.Bpj.2012.11.1204 |
0.834 |
|
| 2012 |
Arnold JJ, Sharma SD, Feng JY, Ray AS, Smidansky ED, Kireeva ML, Cho A, Perry J, Vela JE, Park Y, Xu Y, Tian Y, Babusis D, Barauskus O, Peterson BR, ... ... Cameron CE, et al. Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides. Plos Pathogens. 8: e1003030. PMID 23166498 DOI: 10.1371/Journal.Ppat.1003030 |
0.458 |
|
| 2012 |
Shen H, Moustafa IM, Cameron CE, Colina CM. Exploring the dynamics of four RNA-dependent RNA polymerases by a coarse-grained model. The Journal of Physical Chemistry. B. 116: 14515-24. PMID 23157550 DOI: 10.1021/Jp302709V |
0.474 |
|
| 2012 |
Raney VM, Reynolds KA, Harrison MK, Harrison DK, Cameron CE, Raney KD. Binding by the hepatitis C virus NS3 helicase partially melts duplex DNA. Biochemistry. 51: 7596-607. PMID 22916835 DOI: 10.1021/Bi300654V |
0.312 |
|
| 2012 |
Weeks SA, Lee CA, Zhao Y, Smidansky ED, August A, Arnold JJ, Cameron CE. A Polymerase mechanism-based strategy for viral attenuation and vaccine development. The Journal of Biological Chemistry. 287: 31618-22. PMID 22854962 DOI: 10.1074/Jbc.C112.401471 |
0.372 |
|
| 2012 |
Yang X, Smidansky ED, Maksimchuk KR, Lum D, Welch JL, Arnold JJ, Cameron CE, Boehr DD. Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide addition. Structure (London, England : 1993). 20: 1519-27. PMID 22819218 DOI: 10.1016/J.Str.2012.06.012 |
0.504 |
|
| 2012 |
Lim PJ, Chatterji U, Cordek D, Sharma SD, Garcia-Rivera JA, Cameron CE, Lin K, Targett-Adams P, Gallay PA. Correlation between NS5A dimerization and hepatitis C virus replication. The Journal of Biological Chemistry. 287: 30861-73. PMID 22801423 DOI: 10.1074/Jbc.M112.376822 |
0.401 |
|
| 2012 |
Trahey M, Oh HS, Cameron CE, Hay JC. Poliovirus infection transiently increases COPII vesicle budding. Journal of Virology. 86: 9675-82. PMID 22740409 DOI: 10.1128/Jvi.01159-12 |
0.371 |
|
| 2012 |
Arnold JJ, Smidansky ED, Moustafa IM, Cameron CE. Human mitochondrial RNA polymerase: structure-function, mechanism and inhibition. Biochimica Et Biophysica Acta. 1819: 948-60. PMID 22551784 DOI: 10.1016/J.Bbagrm.2012.04.002 |
0.396 |
|
| 2012 |
Davis WG, Bowzard JB, Sharma SD, Wiens ME, Ranjan P, Gangappa S, Stuchlik O, Pohl J, Donis RO, Katz JM, Cameron CE, Fujita T, Sambhara S. The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I. Plos One. 7: e32661. PMID 22438882 DOI: 10.1371/Journal.Pone.0032661 |
0.405 |
|
| 2012 |
Graci JD, Gnädig NF, Galarraga JE, Castro C, Vignuzzi M, Cameron CE. Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis. Journal of Virology. 86: 2869-73. PMID 22190724 DOI: 10.1128/Jvi.05712-11 |
0.765 |
|
| 2011 |
Gazina EV, Smidansky ED, Holien JK, Harrison DN, Cromer BA, Arnold JJ, Parker MW, Cameron CE, Petrou S. Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase. Journal of Virology. 85: 10364-74. PMID 21795353 DOI: 10.1128/Jvi.05022-11 |
0.514 |
|
| 2011 |
Dutta A, Zheng S, Jain D, Cameron CE, Reese JC. Intermolecular interactions within the abundant DEAD-box protein Dhh1 regulate its activity in vivo. The Journal of Biological Chemistry. 286: 27454-70. PMID 21642421 DOI: 10.1074/Jbc.M111.220251 |
0.512 |
|
| 2011 |
Moustafa IM, Shen H, Morton B, Colina CM, Cameron CE. Molecular dynamics simulations of viral RNA polymerases link conserved and correlated motions of functional elements to fidelity. Journal of Molecular Biology. 410: 159-81. PMID 21575642 DOI: 10.1016/J.Jmb.2011.04.078 |
0.529 |
|
| 2011 |
Smidansky ED, Arnold JJ, Reynolds SL, Cameron CE. Human mitochondrial RNA polymerase: evaluation of the single-nucleotide-addition cycle on synthetic RNA/DNA scaffolds. Biochemistry. 50: 5016-32. PMID 21548588 DOI: 10.1021/Bi200350D |
0.473 |
|
| 2011 |
Cordek DG, Bechtel JT, Maynard AT, Kazmierski WM, Cameron CE. Targeting the NS5A protein of HCV: An emerging option Drugs of the Future. 36: 691-711. DOI: 10.1358/Dof.2011.036.09.1641618 |
0.335 |
|
| 2011 |
Te Velthuis AJW, Arnold JJ, Cameron CE, Van Den Worm SHE, Snijder EJ. The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent (Nucleic Acids Research (2010) 38 (203214) DOI 10.1093/nar/gkp904) Nucleic Acids Research. 39: 9458. DOI: 10.1093/Nar/Gkr963 |
0.478 |
|
| 2011 |
Smidansky ED, Arnold JJ, Reynolds SL, Cameron CE. Correction to Human Mitochondrial RNA Polymerase: Evaluation of the Single-Nucleotide-Addition Cycle on Synthetic RNA/DNA Scaffolds Biochemistry. 50: 5969-5969. DOI: 10.1021/Bi2008454 |
0.501 |
|
| 2010 |
Wu R, Smidansky ED, Oh HS, Takhampunya R, Padmanabhan R, Cameron CE, Peterson BR. Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses. Journal of Medicinal Chemistry. 53: 7958-66. PMID 20964406 DOI: 10.1021/Jm100593S |
0.486 |
|
| 2010 |
Hwang J, Huang L, Cordek DG, Vaughan R, Reynolds SL, Kihara G, Raney KD, Kao CC, Cameron CE. Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins. Journal of Virology. 84: 12480-91. PMID 20926572 DOI: 10.1128/Jvi.01319-10 |
0.693 |
|
| 2010 |
Cline SD, Lodeiro MF, Marnett LJ, Cameron CE, Arnold JJ. Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M1dG. Nucleic Acids Research. 38: 7546-57. PMID 20671026 DOI: 10.1093/Nar/Gkq656 |
0.352 |
|
| 2010 |
Shutt TE, Lodeiro MF, Cotney J, Cameron CE, Shadel GS. Core human mitochondrial transcription apparatus is a regulated two-component system in vitro. Proceedings of the National Academy of Sciences of the United States of America. 107: 12133-8. PMID 20562347 DOI: 10.1073/Pnas.0910581107 |
0.319 |
|
| 2010 |
Cameron CE, Oh HS, Moustafa IM. Expanding knowledge of P3 proteins in the poliovirus lifecycle. Future Microbiology. 5: 867-81. PMID 20521933 DOI: 10.2217/Fmb.10.40 |
0.488 |
|
| 2010 |
Hsu NY, Ilnytska O, Belov G, Santiana M, Chen YH, Takvorian PM, Pau C, van der Schaar H, Kaushik-Basu N, Balla T, Cameron CE, Ehrenfeld E, van Kuppeveld FJ, Altan-Bonnet N. Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell. 141: 799-811. PMID 20510927 DOI: 10.1016/J.Cell.2010.03.050 |
0.557 |
|
| 2010 |
Raney KD, Sharma SD, Moustafa IM, Cameron CE. Hepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral target. The Journal of Biological Chemistry. 285: 22725-31. PMID 20457607 DOI: 10.1074/Jbc.R110.125294 |
0.467 |
|
| 2010 |
Toroney R, Nallagatla SR, Boyer JA, Cameron CE, Bevilacqua PC. Regulation of PKR by HCV IRES RNA: importance of domain II and NS5A. Journal of Molecular Biology. 400: 393-412. PMID 20447405 DOI: 10.1016/J.Jmb.2010.04.059 |
0.448 |
|
| 2010 |
Lodeiro MF, Uchida AU, Arnold JJ, Reynolds SL, Moustafa IM, Cameron CE. Identification of multiple rate-limiting steps during the human mitochondrial transcription cycle in vitro. The Journal of Biological Chemistry. 285: 16387-402. PMID 20351113 DOI: 10.1074/Jbc.M109.092676 |
0.344 |
|
| 2010 |
Matlock DL, Yeruva L, Byrd AK, Mackintosh SG, Langston C, Brown C, Cameron CE, Fischer CJ, Raney KD. Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase. Biochemistry. 49: 2097-109. PMID 20108974 DOI: 10.1021/Bi901977K |
0.396 |
|
| 2010 |
Wang Q, Arnold JJ, Uchida A, Raney KD, Cameron CE. Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase. Nucleic Acids Research. 38: 1312-24. PMID 19969541 DOI: 10.1093/Nar/Gkp1118 |
0.544 |
|
| 2010 |
te Velthuis AJ, Arnold JJ, Cameron CE, van den Worm SH, Snijder EJ. The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent. Nucleic Acids Research. 38: 203-14. PMID 19875418 DOI: 10.1093/Nar/Gkp904 |
0.579 |
|
| 2010 |
Cline SD, Fernanda Lodeiro M, Marnett LJ, Cameron CE, Arnold JJ. 70 Arrest of mitochondrial RNA polymerase by the malondialdehyde adduct, M1dG Mitochondrion. 10: 219. DOI: 10.1016/J.Mito.2009.12.065 |
0.453 |
|
| 2010 |
Lodeiro MF, Uchida A, Reynolds S, Arnold JJ, Cameron CE. 53 Characterization of mitochondrial transcription using bacterially expressed proteins and oligonucleotide templates reveals promoter melting and dinucleotide synthesis as rate-limiting steps in transcription initiation Mitochondrion. 10: 214. DOI: 10.1016/J.Mito.2009.12.049 |
0.301 |
|
| 2010 |
Smidansky ED, Arnold JJ, Reynolds S, Cameron CE. 52 Biochemical characterization of human mitochondrial RNA polymerase reveals differences in formation and fidelity of elongation complexes relative to T7 RNA polymerase Mitochondrion. 10: 214. DOI: 10.1016/J.Mito.2009.12.048 |
0.49 |
|
| 2010 |
Arnold JJ, Smidansky ED, Reynolds S, Cameron CE. 23 The human mitochondrial RNA polymerase as an off target for antiviral ribonucleosides Mitochondrion. 10: 206. DOI: 10.1016/J.Mito.2009.12.022 |
0.445 |
|
| 2009 |
Cameron CE, Moustafa IM, Arnold JJ. Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase? Current Opinion in Structural Biology. 19: 768-74. PMID 19910183 DOI: 10.1016/J.Sbi.2009.10.012 |
0.571 |
|
| 2009 |
Oh HS, Pathak HB, Goodfellow IG, Arnold JJ, Cameron CE. Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants. Journal of Virology. 83: 9370-87. PMID 19587035 DOI: 10.1128/Jvi.02076-08 |
0.768 |
|
| 2009 |
Castro C, Smidansky ED, Arnold JJ, Maksimchuk KR, Moustafa I, Uchida A, Götte M, Konigsberg W, Cameron CE. Nucleic acid polymerases use a general acid for nucleotidyl transfer. Nature Structural & Molecular Biology. 16: 212-8. PMID 19151724 DOI: 10.1038/Nsmb.1540 |
0.414 |
|
| 2009 |
Jennings TA, Mackintosh SG, Harrison MK, Sikora D, Sikora B, Dave B, Tackett AJ, Cameron CE, Raney KD. NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations. The Journal of Biological Chemistry. 284: 4806-14. PMID 19088075 DOI: 10.1074/Jbc.M805540200 |
0.381 |
|
| 2009 |
Cameron CE, Raney KD, Götte M. Viral genome replication Viral Genome Replication. 1-636. DOI: 10.1007/b135974 |
0.338 |
|
| 2008 |
Graci JD, Cameron CE. Therapeutically targeting RNA viruses via lethal mutagenesis. Future Virology. 3: 553-566. PMID 19727424 DOI: 10.2217/17460794.3.6.553 |
0.81 |
|
| 2008 |
Arias A, Arnold JJ, Sierra M, Smidansky ED, Domingo E, Cameron CE. Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin. Journal of Virology. 82: 12346-55. PMID 18829745 DOI: 10.1128/Jvi.01297-08 |
0.479 |
|
| 2008 |
Pathak HB, Oh HS, Goodfellow IG, Arnold JJ, Cameron CE. Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylation. The Journal of Biological Chemistry. 283: 30677-88. PMID 18779320 DOI: 10.1074/Jbc.M806101200 |
0.774 |
|
| 2008 |
Sun Q, Edathil JP, Wu R, Smidansky ED, Cameron CE, Peterson BR. One-pot synthesis of nucleoside 5'-triphosphates from nucleoside 5'-H-phosphonates. Organic Letters. 10: 1703-6. PMID 18393512 DOI: 10.1021/Ol8003029 |
0.526 |
|
| 2008 |
Amero CD, Arnold JJ, Moustafa IM, Cameron CE, Foster MP. Identification of the oriI-binding site of poliovirus 3C protein by nuclear magnetic resonance spectroscopy Journal of Virology. 82: 4363-4370. PMID 18305026 DOI: 10.1128/Jvi.02087-07 |
0.532 |
|
| 2008 |
Sikora B, Chen Y, Lichti CF, Harrison MK, Jennings TA, Tang Y, Tackett AJ, Jordan JB, Sakon J, Cameron CE, Raney KD. Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. The Journal of Biological Chemistry. 283: 11516-25. PMID 18283103 DOI: 10.1074/Jbc.M708125200 |
0.384 |
|
| 2008 |
Ng KK, Arnold JJ, Cameron CE. Structure-function relationships among RNA-dependent RNA polymerases. Current Topics in Microbiology and Immunology. 320: 137-56. PMID 18268843 DOI: 10.1007/978-3-540-75157-1_7 |
0.579 |
|
| 2008 |
Graci JD, Too K, Smidansky ED, Edathil JP, Barr EW, Harki DA, Galarraga JE, Bollinger JM, Peterson BR, Loakes D, Brown DM, Cameron CE. Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues. Antimicrobial Agents and Chemotherapy. 52: 971-9. PMID 18180344 DOI: 10.1128/Aac.01056-07 |
0.803 |
|
| 2008 |
Jennings TA, Chen Y, Sikora D, Harrison MK, Sikora B, Huang L, Jankowsky E, Fairman ME, Cameron CE, Raney KD. RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase. Biochemistry. 47: 1126-35. PMID 18179252 DOI: 10.1021/Bi701048A |
0.481 |
|
| 2008 |
Moriyama K, Suzuki T, Negishi K, Graci JD, Thompson CN, Cameron CE, Watanabe M. Effects of introduction of hydrophobic group on ribavirin base on mutation induction and anti-RNA viral activity. Journal of Medicinal Chemistry. 51: 159-66. PMID 18067241 DOI: 10.1021/Jm7009952 |
0.778 |
|
| 2008 |
Shen M, Reitman ZJ, Zhao Y, Moustafa I, Wang Q, Arnold JJ, Pathak HB, Cameron CE. Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex. The Journal of Biological Chemistry. 283: 875-88. PMID 17993457 DOI: 10.1074/Jbc.M707907200 |
0.75 |
|
| 2008 |
Smidansky ED, Arnold JJ, Cameron CE. Nucleic Acid Polymerase Fidelity and Viral Population Fitness Origin and Evolution of Viruses. 135-160. DOI: 10.1016/B978-0-12-374153-0.00006-0 |
0.384 |
|
| 2007 |
Nallagatla SR, Hwang J, Toroney R, Zheng X, Cameron CE, Bevilacqua PC. 5'-triphosphate-dependent activation of PKR by RNAs with short stem-loops. Science (New York, N.Y.). 318: 1455-8. PMID 18048689 DOI: 10.1126/Science.1147347 |
0.698 |
|
| 2007 |
Shen M, Wang Q, Yang Y, Pathak HB, Arnold JJ, Castro C, Lemon SM, Cameron CE. Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complex. Journal of Virology. 81: 12485-95. PMID 17855535 DOI: 10.1128/Jvi.00972-07 |
0.705 |
|
| 2007 |
Graci JD, Harki DA, Korneeva VS, Edathil JP, Too K, Franco D, Smidansky ED, Paul AV, Peterson BR, Brown DM, Loakes D, Cameron CE. Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue. Journal of Virology. 81: 11256-66. PMID 17686844 DOI: 10.1128/Jvi.01028-07 |
0.831 |
|
| 2007 |
Harki DA, Graci JD, Edathil JP, Castro C, Cameron CE, Peterson BR. Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase. Chembiochem : a European Journal of Chemical Biology. 8: 1359-62. PMID 17600792 DOI: 10.1002/Cbic.200700160 |
0.832 |
|
| 2007 |
Korneeva VS, Cameron CE. Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket. The Journal of Biological Chemistry. 282: 16135-45. PMID 17400557 DOI: 10.1074/Jbc.M610090200 |
0.846 |
|
| 2007 |
Pathak HB, Arnold JJ, Wiegand PN, Hargittai MR, Cameron CE. Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. The Journal of Biological Chemistry. 282: 16202-13. PMID 17392285 DOI: 10.1074/Jbc.M610608200 |
0.728 |
|
| 2007 |
Castro C, Smidansky E, Maksimchuk KR, Arnold JJ, Korneeva VS, Götte M, Konigsberg W, Cameron CE. Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 104: 4267-72. PMID 17360513 DOI: 10.1073/Pnas.0608952104 |
0.8 |
|
| 2007 |
Marcotte LL, Wass AB, Gohara DW, Pathak HB, Arnold JJ, Filman DJ, Cameron CE, Hogle JM. Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. Journal of Virology. 81: 3583-96. PMID 17251299 DOI: 10.1128/Jvi.02306-06 |
0.705 |
|
| 2006 |
Huang L, Gledhill J, Cameron CE. Protocol for siRNA-Primed RNA Synthesis. Csh Protocols. 2006. PMID 22485702 DOI: 10.1101/pdb.prot4326 |
0.387 |
|
| 2006 |
Huang L, Gledhill J, Cameron CE. Assay for Primed RNA-Dependent RNA Polymerase Transcription. Csh Protocols. 2006. PMID 22485699 DOI: 10.1101/pdb.prot4323 |
0.414 |
|
| 2006 |
Huang L, Gledhill J, Cameron CE. An Assay for RNA-Dependent RNA Polymerase Activity. Csh Protocols. 2006. PMID 22485698 DOI: 10.1101/pdb.prot4322 |
0.434 |
|
| 2006 |
Harki DA, Graci JD, Galarraga JE, Chain WJ, Cameron CE, Peterson BR. Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases. Journal of Medicinal Chemistry. 49: 6166-9. PMID 17034123 DOI: 10.1021/Jm060872X |
0.815 |
|
| 2006 |
D'Abramo CM, Deval J, Cameron CE, Cellai L, Götte M. Control of template positioning during de novo initiation of RNA synthesis by the bovine viral diarrhea virus NS5B polymerase. The Journal of Biological Chemistry. 281: 24991-8. PMID 16831816 DOI: 10.1074/Jbc.M600474200 |
0.516 |
|
| 2006 |
Takhampunya R, Ubol S, Houng HS, Cameron CE, Padmanabhan R. Inhibition of dengue virus replication by mycophenolic acid and ribavirin. The Journal of General Virology. 87: 1947-52. PMID 16760396 DOI: 10.1099/Vir.0.81655-0 |
0.527 |
|
| 2006 |
Lanzi G, de Miranda JR, Boniotti MB, Cameron CE, Lavazza A, Capucci L, Camazine SM, Rossi C. Molecular and biological characterization of deformed wing virus of honeybees (Apis mellifera L.). Journal of Virology. 80: 4998-5009. PMID 16641291 DOI: 10.1128/Jvi.80.10.4998-5009.2006 |
0.497 |
|
| 2006 |
van Ooij MJ, Vogt DA, Paul A, Castro C, Kuijpers J, van Kuppeveld FJ, Cameron CE, Wimmer E, Andino R, Melchers WJ. Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. The Journal of General Virology. 87: 103-13. PMID 16361422 DOI: 10.1099/Vir.0.81297-0 |
0.545 |
|
| 2006 |
Arnold JJ, Bernal A, Uche U, Sterner DE, Butt TR, Cameron CE, Mattern MR. Small ubiquitin-like modifying protein isopeptidase assay based on poliovirus RNA polymerase activity. Analytical Biochemistry. 350: 214-21. PMID 16356462 DOI: 10.1016/J.Ab.2005.11.001 |
0.442 |
|
| 2006 |
Vignuzzi M, Stone JK, Arnold JJ, Cameron CE, Andino R. Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature. 439: 344-8. PMID 16327776 DOI: 10.1038/Nature04388 |
0.47 |
|
| 2006 |
Mackintosh SG, Lu JZ, Jordan JB, Harrison MK, Sikora B, Sharma SD, Cameron CE, Raney KD, Sakon J. Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus. The Journal of Biological Chemistry. 281: 3528-35. PMID 16306038 DOI: 10.1074/Jbc.M512100200 |
0.459 |
|
| 2006 |
Graci JD, Cameron CE. Mechanisms of action of ribavirin against distinct viruses. Reviews in Medical Virology. 16: 37-48. PMID 16287208 DOI: 10.1002/Rmv.483 |
0.767 |
|
| 2005 |
Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virology Journal. 2: 86. PMID 16300678 DOI: 10.1186/1743-422X-2-86 |
0.786 |
|
| 2005 |
Huang L, Hwang J, Sharma SD, Hargittai MR, Chen Y, Arnold JJ, Raney KD, Cameron CE. Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. The Journal of Biological Chemistry. 280: 36417-28. PMID 16126720 DOI: 10.1074/Jbc.M508175200 |
0.691 |
|
| 2005 |
Arnold JJ, Vignuzzi M, Stone JK, Andino R, Cameron CE. Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. The Journal of Biological Chemistry. 280: 25706-16. PMID 15878882 DOI: 10.1074/Jbc.M503444200 |
0.545 |
|
| 2005 |
Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Journal of Virology. 79: 6358-67. PMID 15858019 DOI: 10.1128/Jvi.79.10.6358-6367.2005 |
0.765 |
|
| 2005 |
Belliot G, Sosnovtsev SV, Chang KO, Babu V, Uche U, Arnold JJ, Cameron CE, Green KY. Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase. Journal of Virology. 79: 2393-403. PMID 15681440 DOI: 10.1128/Jvi.79.4.2393-2403.2005 |
0.559 |
|
| 2005 |
Castro C, Arnold JJ, Cameron CE. Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective. Virus Research. 107: 141-9. PMID 15649560 DOI: 10.1016/J.Virusres.2004.11.004 |
0.605 |
|
| 2005 |
Tackett AJ, Chen Y, Cameron CE, Raney KD. Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro. The Journal of Biological Chemistry. 280: 10797-806. PMID 15634684 DOI: 10.1074/Jbc.M407971200 |
0.368 |
|
| 2005 |
Graci JD, Cameron CE. Lethal Mutagenesis: Exploiting Error-Prone Replication of Riboviruses for Antiviral Therapy Antiviral Drug Discovery For Emerging Diseases and Bioterrorism Threats. 203-220. DOI: 10.1002/0471716715.ch9 |
0.755 |
|
| 2004 |
Huang L, Sineva EV, Hargittai MR, Sharma SD, Suthar M, Raney KD, Cameron CE. Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli. Protein Expression and Purification. 37: 144-53. PMID 15294292 DOI: 10.1016/J.Pep.2004.05.005 |
0.428 |
|
| 2004 |
de Miranda JR, Drebot M, Tyler S, Shen M, Cameron CE, Stoltz DB, Camazine SM. Complete nucleotide sequence of Kashmir bee virus and comparison with acute bee paralysis virus Journal of General Virology. 85: 2263-2270. PMID 15269367 DOI: 10.1099/Vir.0.79990-0 |
0.399 |
|
| 2004 |
Gohara DW, Arnold JJ, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection. Biochemistry. 43: 5149-58. PMID 15122880 DOI: 10.1021/Bi035429S |
0.556 |
|
| 2004 |
Arnold JJ, Gohara DW, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+. Biochemistry. 43: 5138-48. PMID 15122879 DOI: 10.1021/bi035213q |
0.352 |
|
| 2004 |
Arnold JJ, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+. Biochemistry. 43: 5126-37. PMID 15122878 DOI: 10.1021/Bi035212Y |
0.54 |
|
| 2004 |
Graci JD, Cameron CE. Challenges for the development of ribonucleoside analogues as inducers of error catastrophe. Antiviral Chemistry & Chemotherapy. 15: 1-13. PMID 15074710 DOI: 10.1177/095632020401500101 |
0.801 |
|
| 2004 |
Freistadt MS, Meades GD, Cameron CE. Lethal mutagens: broad-spectrum antivirals with limited potential for development of resistance? Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 7: 19-24. PMID 15072768 DOI: 10.1016/j.drup.2003.12.003 |
0.382 |
|
| 2003 |
Crotty S, Gohara D, Gilligan DK, Karelsky S, Cameron CE, Andino R. Manganese-dependent polioviruses caused by mutations within the viral polymerase. Journal of Virology. 77: 5378-88. PMID 12692240 DOI: 10.1128/Jvi.77.9.5378-5388.2003 |
0.607 |
|
| 2002 |
Hong Z, Cameron CE. Pleiotropic mechanisms of ribavirin antiviral activities. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 59: 41-69. PMID 12458963 DOI: 10.1007/978-3-0348-8171-5_2 |
0.545 |
|
| 2002 |
Gorbalenya AE, Pringle FM, Zeddam JL, Luke BT, Cameron CE, Kalmakoff J, Hanzlik TN, Gordon KH, Ward VK. The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage. Journal of Molecular Biology. 324: 47-62. PMID 12421558 DOI: 10.1016/S0022-2836(02)01033-1 |
0.574 |
|
| 2002 |
Green KY, Mory A, Fogg MH, Weisberg A, Belliot G, Wagner M, Mitra T, Ehrenfeld E, Cameron CE, Sosnovtsev SV. Isolation of enzymatically active replication complexes from feline calicivirus-infected cells. Journal of Virology. 76: 8582-95. PMID 12163578 DOI: 10.1128/Jvi.76.17.8582-8595.2002 |
0.527 |
|
| 2002 |
Graci JD, Cameron CE. Quasispecies, error catastrophe, and the antiviral activity of ribavirin. Virology. 298: 175-80. PMID 12127780 DOI: 10.1006/Viro.2002.1487 |
0.787 |
|
| 2002 |
Harki DA, Graci JD, Korneeva VS, Ghosh SK, Hong Z, Cameron CE, Peterson BR. Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole. Biochemistry. 41: 9026-33. PMID 12119016 DOI: 10.1021/Bi026120W |
0.823 |
|
| 2002 |
Pathak HB, Ghosh SK, Roberts AW, Sharma SD, Yoder JD, Arnold JJ, Gohara DW, Barton DJ, Paul AV, Cameron CE. Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. The Journal of Biological Chemistry. 277: 31551-62. PMID 12077141 DOI: 10.1074/Jbc.M204408200 |
0.749 |
|
| 2002 |
Crotty S, Cameron C, Andino R. Ribavirin's antiviral mechanism of action: lethal mutagenesis? Journal of Molecular Medicine (Berlin, Germany). 80: 86-95. PMID 11907645 DOI: 10.1007/S00109-001-0308-0 |
0.522 |
|
| 2002 |
Morris PD, Byrd AK, Tackett AJ, Cameron CE, Tanega P, Ott R, Fanning E, Raney KD. Hepatitis C virus NS3 and simian virus 40 T antigen helicases displace streptavidin from 5'-biotinylated oligonucleotides but not from 3'-biotinylated oligonucleotides: evidence for directional bias in translocation on single-stranded DNA. Biochemistry. 41: 2372-8. PMID 11841230 DOI: 10.1021/Bi012058B |
0.413 |
|
| 2001 |
Cameron CE, Castro C. The mechanism of action of ribavirin: Lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase Current Opinion in Infectious Diseases. 14: 757-764. PMID 11964896 DOI: 10.1097/00001432-200112000-00015 |
0.569 |
|
| 2001 |
Maag D, Castro C, Hong Z, Cameron CE. Hepatitis C Virus RNA-dependent RNA Polymerase (NS5B) as a Mediator of the Antiviral Activity of Ribavirin Journal of Biological Chemistry. 276: 46094-46098. PMID 11602568 DOI: 10.1074/Jbc.C100349200 |
0.476 |
|
| 2001 |
Hong Z, Cameron CE, Walker MP, Castro C, Yao N, Lau JY, Zhong W. A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase. Virology. 285: 6-11. PMID 11414800 DOI: 10.1006/Viro.2001.0948 |
0.57 |
|
| 2001 |
Crotty S, Cameron CE, Andino R. RNA virus error catastrophe: direct molecular test by using ribavirin. Proceedings of the National Academy of Sciences of the United States of America. 98: 6895-900. PMID 11371613 DOI: 10.1073/Pnas.111085598 |
0.571 |
|
| 2001 |
Wei L, Huhn JS, Mory A, Pathak HB, Sosnovtsev SV, Green KY, Cameron CE. Proteinase-polymerase precursor as the active form of feline calicivirus RNA-dependent RNA polymerase. Journal of Virology. 75: 1211-9. PMID 11152494 DOI: 10.1128/Jvi.75.3.1211-1219.2001 |
0.744 |
|
| 2001 |
Tackett AJ, Wei L, Cameron CE, Raney KD. Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex. Nucleic Acids Research. 29: 565-72. PMID 11139627 DOI: 10.1093/Nar/29.2.565 |
0.384 |
|
| 2000 |
Crotty S, Maag D, Arnold JJ, Zhong W, Lau JY, Hong Z, Andino R, Cameron CE. The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature Medicine. 6: 1375-9. PMID 11100123 DOI: 10.1038/82191 |
0.572 |
|
| 2000 |
Zhong W, Ferrari E, Lesburg CA, Maag D, Ghosh SKB, Cameron CE, Lau JYN, Hong Z. Template/primer requirements and single nucleotide incorporation by Hepatitis C virus nonstructural protein 5B polymerase Journal of Virology. 74: 9134-9143. PMID 10982360 DOI: 10.1128/Jvi.74.19.9134-9143.2000 |
0.571 |
|
| 2000 |
Gohara DW, Crotty S, Arnold JJ, Yoder JD, Andino R, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B. The Journal of Biological Chemistry. 275: 25523-32. PMID 10827187 DOI: 10.1074/Jbc.M002671200 |
0.55 |
|
| 2000 |
Arnold JJ, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub) Journal of Biological Chemistry. 275: 5329-5336. PMID 10681506 DOI: 10.1074/Jbc.275.8.5329 |
0.438 |
|
| 1999 |
Arnold JJ, Ghosh SKB, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selection Journal of Biological Chemistry. 274: 37060-37069. PMID 10601264 DOI: 10.1074/Jbc.274.52.37060 |
0.48 |
|
| 1999 |
Gohara DW, Ha CS, Kumar S, Ghosh B, Arnold JJ, Wisniewski TJ, Cameron CE. Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli. Protein Expression and Purification. 17: 128-38. PMID 10497078 DOI: 10.1006/Prep.1999.1100 |
0.459 |
|
| 1999 |
Arnold JJ, Ghosh SK, Bevilacqua PC, Cameron CE. Single-nucleotide resolution of RNA strands in the presence of their RNA complements. Biotechniques. 27: 450-2, 454, 456. PMID 10489603 DOI: 10.2144/99273Bm11 |
0.526 |
|
| 1999 |
Arnold JJ, Cameron CE. Poliovirus RNA-dependent RNA polymerase (3D(pol)) is sufficient for template switching in vitro Journal of Biological Chemistry. 274: 2706-2716. PMID 9915801 DOI: 10.1074/Jbc.274.5.2706 |
0.523 |
|
| 1997 |
Cameron CE, Benkovic SJ. Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant Biochemistry. 36: 15792-15800. PMID 9398309 DOI: 10.1021/Bi9716231 |
0.502 |
|
| 1997 |
Cameron CE, Ghosh M, Le Grice SFJ, Benkovic SJ. Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein Proceedings of the National Academy of Sciences of the United States of America. 94: 6700-6705. PMID 9192628 DOI: 10.1073/Pnas.94.13.6700 |
0.579 |
|
| 1997 |
Shao H, Robek MD, Threadgill DS, Mankowski LS, Cameron CE, Fuller FJ, Payne SL. Characterization and mutational studies of equine infectious anemia virus dUTPase. Biochimica Et Biophysica Acta. 1339: 181-91. PMID 9187238 DOI: 10.1016/S0167-4838(96)00229-4 |
0.414 |
|
| 1996 |
Xiang Y, Cameron CE, Wills JW, Leis J. Fine mapping and characterization of the Rous sarcoma virus Pr76(gag) late assembly domain Journal of Virology. 70: 5695-5700. PMID 8764091 DOI: 10.1128/Jvi.70.8.5695-5700.1996 |
0.632 |
|
| 1996 |
Ridky TW, Bizub-Bender D, Cameron CE, Weber IT, Wlodawer A, Copeland T, Skalka AM, Leis J. Programming the Rous sarcoma virus protease to cleave new substrate sequences. The Journal of Biological Chemistry. 271: 10538-44. PMID 8631853 DOI: 10.1074/Jbc.271.18.10538 |
0.617 |
|
| 1996 |
Ridky TW, Cameron CE, Cameron J, Leis J, Copeland T, Wlodawer A, Weber IT, Harrison RW. Human immunodeficiency virus, type 1 protease substrate specificity is limited by interactions between substrate amino acids bound in adjacent enzyme subsites Journal of Biological Chemistry. 271: 4709-4717. PMID 8617736 DOI: 10.1074/Jbc.271.9.4709 |
0.597 |
|
| 1996 |
Xiang Y, Cameron CE, Wills JW, Leis J. Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain. Journal of Virology. 70: 5695-5700. DOI: 10.1128/jvi.70.8.5695-5700.1996 |
0.554 |
|
| 1995 |
Benkovic SJ, Cameron CE. Kinetic analysis of nucleotide incorporation and misincorporation by Klenow fragment of Escherichia coli DNA polymerase I Methods in Enzymology. 262: 257-269. PMID 8594352 DOI: 10.1016/0076-6879(95)62022-2 |
0.502 |
|
| 1995 |
Le Grice SFJ, Cameron CE, Benkovic SJ. Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase Methods in Enzymology. 262: 130-144. PMID 8594344 DOI: 10.1016/0076-6879(95)62015-X |
0.493 |
|
| 1995 |
Cameron CE, Burstein H, Bizub-Bender D, Ridky T, Weber IT, Wlodawer A, Skalka AM, Leis J. Identification of amino acid residues of the retroviral aspartic proteinases important for substrate specificity and catalytic efficiency. Advances in Experimental Medicine and Biology. 362: 399-406. PMID 8540349 DOI: 10.1007/978-1-4615-1871-6_52 |
0.601 |
|
| 1995 |
Cirino NM, Cameron CE, Smith JS, Rausch JW, Roth MJ, Benkovic SJ, Le Grice SFJ. Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase Biochemistry. 34: 9936-9943. PMID 7543283 DOI: 10.1021/Bi00031A016 |
0.621 |
|
| 1995 |
Ghosh M, Howard KJ, Cameron CE, Benkovic SJ, Hughes SH, Le Grice SFJ. Truncating α-Helix E′ of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer Journal of Biological Chemistry. 270: 7068-7076. PMID 7535765 DOI: 10.1074/Jbc.270.13.7068 |
0.541 |
|
| 1994 |
Wills JW, Cameron CE, Wilson CB, Xiang Y, Bennett RP, Leis J. An assembly domain of the Rous sarcoma virus Gag protein required late in budding Journal of Virology. 68: 6605-6618. PMID 8083996 DOI: 10.1128/Jvi.68.10.6605-6618.1994 |
0.621 |
|
| 1994 |
Leis JP, Cameron CE. Engineering proteases with altered specificity Current Opinion in Biotechnology. 5: 403-408. PMID 7765173 DOI: 10.1016/0958-1669(94)90049-3 |
0.625 |
|
| 1994 |
Wills JW, Cameron CE, Wilson CB, Xiang Y, Bennett RP, Leis J. An assembly domain of the Rous sarcoma virus Gag protein required late in budding. Journal of Virology. 68: 6605-6618. DOI: 10.1128/jvi.68.10.6605-6618.1994 |
0.579 |
|
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