Clark W. Distelhorst - Publications

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Cell Biology, Biochemistry

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Harr MW, Lavik A, McColl K, Zhong F, Haberer B, Aldabbagh K, Yee V, Distelhorst CW. A Novel Peptide that Disrupts the Lck-IPR Protein-Protein Interaction Induces Widespread Cell Death in Leukemia and Lymphoma. Archives of Microbiology & Immunology. 7: 165-177. PMID 37829571 DOI: 10.26502/ami.936500114  0.327
2023 Harr M, Lavik A, McColl K, Zhong F, Haberer B, Aldabbagh K, Yee V, Distelhorst CW. A novel peptide that disrupts the Lck-IP3R protein-protein interaction induces widespread cell death in leukemia and lymphoma. Research Square. PMID 36711753 DOI: 10.21203/rs.3.rs-2436910/v1  0.327
2019 Distelhorst CW, Bootman MD. Creating a New Cancer Therapeutic Agent by Targeting the Interaction between Bcl-2 and IP Receptors. Cold Spring Harbor Perspectives in Biology. PMID 31110129 DOI: 10.1101/Cshperspect.A035196  0.458
2018 Distelhorst CW. Targeting Bcl-2-IP receptor interaction to treat cancer: A novel approach inspired by nearly a century treating cancer with adrenal corticosteroid hormones. Biochimica Et Biophysica Acta. PMID 30053503 DOI: 10.1016/J.Bbamcr.2018.07.020  0.511
2016 Vatolin S, Phillips JG, Jha BK, Govindgari S, Hu JC, Grabowski D, Parker Y, Lindner DJ, Zhong F, Distelhorst CW, Smith MR, Cotta C, Xu Y, Chilakala S, Kuang RR, et al. Novel protein disulfide isomerase inhibitor with anti-cancer activity in multiple myeloma. Cancer Research. PMID 27197150 DOI: 10.1158/0008-5472.Can-15-3099  0.414
2015 Greenberg EF, McColl KS, Zhong F, Wildey G, Dowlati A, Distelhorst CW. Synergistic killing of human small cell lung cancer cells by the Bcl-2-inositol 1,4,5-trisphosphate receptor disruptor BIRD-2 and the BH3-mimetic ABT-263. Cell Death & Disease. 6: e2034. PMID 26720343 DOI: 10.1038/Cddis.2015.355  0.524
2015 Lavik AR, Zhong F, Chang MJ, Greenberg E, Choudhary Y, Smith MR, McColl KS, Pink J, Reu FJ, Matsuyama S, Distelhorst CW. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2. Oncotarget. PMID 26317541 DOI: 10.18632/Oncotarget.4489  0.475
2015 Lavik AR, Zhong F, Chang MJ, Greenberg E, Choudhary Y, Smith MR, McColl KS, Pink J, Reu FJ, Matsuyama S, Distelhorst CW. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2 Oncotarget. 6: 27388-27402. DOI: 10.18632/oncotarget.4489  0.415
2014 Rosko AE, McColl KS, Zhong F, Ryder CB, Chang MJ, Sattar A, Caimi PF, Hill BT, Al-Harbi S, Almasan A, Distelhorst CW. Acidosis Sensing Receptor GPR65 Correlates with Anti-Apoptotic Bcl-2 Family Member Expression in CLL Cells: Potential Implications for the CLL Microenvironment. Journal of Leukemia (Los Angeles, Calif.). 2. PMID 25984552 DOI: 10.4172/2329-6917.1000160  0.41
2014 Greenberg EF, Lavik AR, Distelhorst CW. Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment. Biochimica Et Biophysica Acta. 1843: 2205-10. PMID 24642270 DOI: 10.1016/J.Bbamcr.2014.03.008  0.429
2014 Chang MJ, Zhong F, Lavik AR, Parys JB, Berridge MJ, Distelhorst CW. Feedback regulation mediated by Bcl-2 and DARPP-32 regulates inositol 1,4,5-trisphosphate receptor phosphorylation and promotes cell survival. Proceedings of the National Academy of Sciences of the United States of America. 111: 1186-91. PMID 24395794 DOI: 10.1073/Pnas.1323098111  0.467
2013 Liu WM, Huang P, Kar N, Burgett M, Muller-Greven G, Nowacki AS, Distelhorst CW, Lathia JD, Rich JN, Kappes JC, Gladson CL. Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy. Plos One. 8: e70804. PMID 23936469 DOI: 10.1371/Journal.Pone.0070804  0.448
2013 Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G. IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2. Cell Death & Disease. 4: e632. PMID 23681227 DOI: 10.1038/cddis.2013.140  0.43
2013 Ryder CB, McColl K, Distelhorst CW. Acidosis blocks CCAAT/enhancer-binding protein homologous protein (CHOP)- and c-Jun-mediated induction of p53-upregulated mediator of apoptosis (PUMA) during amino acid starvation. Biochemical and Biophysical Research Communications. 430: 1283-8. PMID 23261451 DOI: 10.1016/J.Bbrc.2012.11.136  0.459
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Distelhorst CW, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.326
2012 Ryder C, McColl K, Zhong F, Distelhorst CW. Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. The Journal of Biological Chemistry. 287: 27863-75. PMID 22685289 DOI: 10.1074/Jbc.M112.384685  0.511
2012 Monaco G, Decrock E, Akl H, Ponsaerts R, Vervliet T, Luyten T, De Maeyer M, Missiaen L, Distelhorst CW, De Smedt H, Parys JB, Leybaert L, Bultynck G. Selective regulation of IP 3-receptor-mediated Ca 2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl Cell Death and Differentiation. 19: 295-309. PMID 21818117 DOI: 10.1038/Cdd.2011.97  0.465
2011 Molitoris JK, McColl KS, Swerdlow S, Matsuyama M, Lam M, Finkel TH, Matsuyama S, Distelhorst CW. Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes. The Journal of Biological Chemistry. 286: 30181-9. PMID 21733849 DOI: 10.1074/Jbc.M111.245423  0.54
2011 Distelhorst CW, Bootman MD. Bcl-2 interaction with the inositol 1,4,5-trisphosphate receptor: role in Ca(2+) signaling and disease. Cell Calcium. 50: 234-41. PMID 21628070 DOI: 10.1016/J.Ceca.2011.05.011  0.37
2011 Molitoris JK, McColl KS, Distelhorst CW. Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis. Molecular Endocrinology (Baltimore, Md.). 25: 409-20. PMID 21239610 DOI: 10.1210/Me.2010-0402  0.369
2011 Zhong F, Harr MW, Bultynck G, Monaco G, Parys JB, De Smedt H, Rong YP, Molitoris JK, Lam M, Ryder C, Matsuyama S, Distelhorst CW. Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction. Blood. 117: 2924-34. PMID 21193695 DOI: 10.1182/Blood-2010-09-307405  0.476
2011 Distelhorst CW. Autophagy and Metabolism in Lymphoid Malignancies Blood. 118: SCI-26-SCI-26. DOI: 10.1182/Blood.V118.21.Sci-26.Sci-26  0.523
2011 Molitoris JK, McColl KS, Swerdlow S, Matsuyama M, Lam M, Finkel TH, Matsuyama S, Distelhorst CW. Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes (Journal of Biological Chemistry (2011) 286, (30181-30189)) Journal of Biological Chemistry. 286: 39673. DOI: 10.1074/Jbc.A111.245423  0.416
2010 Harr MW, Distelhorst CW. Apoptosis and autophagy: decoding calcium signals that mediate life or death. Cold Spring Harbor Perspectives in Biology. 2: a005579. PMID 20826549 DOI: 10.1101/Cshperspect.A005579  0.452
2010 Harr MW, McColl KS, Zhong F, Molitoris JK, Distelhorst CW. Glucocorticoids downregulate Fyn and inhibit IP(3)-mediated calcium signaling to promote autophagy in T lymphocytes. Autophagy. 6: 912-21. PMID 20814235 DOI: 10.4161/Auto.6.7.13290  0.432
2010 Harr MW, Caimi PF, McColl KS, Zhong F, Patel SN, Barr PM, Distelhorst CW. Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia. Cell Death and Differentiation. 17: 1381-91. PMID 20300113 DOI: 10.1038/cdd.2010.25  0.441
2009 Harr MW, Rong Y, Bootman MD, Roderick HL, Distelhorst CW. Glucocorticoid-mediated inhibition of Lck modulates the pattern of T cell receptor-induced calcium signals by down-regulating inositol 1,4,5-trisphosphate receptors. The Journal of Biological Chemistry. 284: 31860-71. PMID 19776014 DOI: 10.1074/Jbc.M109.005579  0.399
2009 Rong YP, Bultynck G, Aromolaran AS, Zhong F, Parys JB, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proceedings of the National Academy of Sciences of the United States of America. 106: 14397-402. PMID 19706527 DOI: 10.1073/Pnas.0907555106  0.482
2009 Rong YP, Barr P, Yee VC, Distelhorst CW. Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor. Biochimica Et Biophysica Acta. 1793: 971-8. PMID 19056433 DOI: 10.1016/j.bbamcr.2008.10.015  0.41
2009 Harr MW, Caimi PF, McColl K, Zhong F, Patel SN, Barr P, Distelhorst CW. The Tyrosine Kinase Inhibitor Dasatinib Enhances Glucocorticoid-Induced Apoptosis and Sensitizes Chronic Lymphocytic Leukemia Cells to Dexamethasone. Blood. 114: 4811-4811. DOI: 10.1182/Blood.V114.22.4811.4811  0.442
2009 Harr MW, Distelhorst CW. The endoplasmic reticulum pathway Essentials of Apoptosis: a Guide For Basic and Clinical Research. 177-197. DOI: 10.1007/978-1-60327-381-7_7  0.407
2008 Rong YP, Aromolaran AS, Bultynck G, Zhong F, Li X, McColl K, Matsuyama S, Herlitze S, Roderick HL, Bootman MD, Mignery GA, Parys JB, De Smedt H, Distelhorst CW. Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Molecular Cell. 31: 255-65. PMID 18657507 DOI: 10.1016/J.Molcel.2008.06.014  0.518
2008 Hanson CJ, Bootman MD, Distelhorst CW, Wojcikiewicz RJ, Roderick HL. Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content. Cell Calcium. 44: 324-38. PMID 18407350 DOI: 10.1016/j.ceca.2008.01.003  0.375
2008 Swerdlow S, McColl K, Rong Y, Lam M, Gupta A, Distelhorst CW. Apoptosis inhibition by Bcl-2 gives way to autophagy in glucocorticoid-treated lymphocytes. Autophagy. 4: 612-20. PMID 18362516 DOI: 10.4161/Auto.5920  0.546
2008 Davis MC, McColl KS, Zhong F, Wang Z, Malone MH, Distelhorst CW. Dexamethasone-induced inositol 1,4,5-trisphosphate receptor elevation in murine lymphoma cells is not required for dexamethasone-mediated calcium elevation and apoptosis. The Journal of Biological Chemistry. 283: 10357-65. PMID 18272518 DOI: 10.1074/Jbc.M800269200  0.467
2008 Hanson CJ, Bootman MD, Distelhorst CW, Maraldi T, Roderick HL. The cellular concentration of Bcl-2 determines its pro- or anti-apoptotic effect. Cell Calcium. 44: 243-58. PMID 18215418 DOI: 10.1016/j.ceca.2007.11.014  0.471
2008 Rong Y, Distelhorst CW. Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis. Annual Review of Physiology. 70: 73-91. PMID 17680735 DOI: 10.1146/Annurev.Physiol.70.021507.105852  0.509
2008 Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, Distelhorst CW. Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis (Oncogene (2006) 25, (1903-1913) DOI: 10.1038/sj.onc.1209218)) Oncogene. 27: 1342. DOI: 10.1038/Sj.Onc.1211001  0.458
2007 Swerdlow S, Distelhorst CW. Bcl-2-regulated calcium signals as common mediators of both apoptosis and autophagy. Developmental Cell. 12: 178-9. PMID 17276336 DOI: 10.1016/j.devcel.2007.01.008  0.367
2006 Davis MC, Distelhorst CW. Live free or die: an immature T cell decision encoded in distinct Bcl-2 sensitive and insensitive Ca2+ signals. Cell Cycle (Georgetown, Tex.). 5: 1171-4. PMID 16721059 DOI: 10.4161/Cc.5.11.2778  0.399
2006 Lam M, Stallcup M, Distelhorst CW. Expression of a defective mouse mammary tumor virus envelope glycoprotein precursor which binds stably to GRP78 within the lumen of the endoplasmic reticulum is associated with decreased glucocorticoid-induced apoptosis in mouse lymphoma cells. Cell Death and Differentiation. 4: 283-8. PMID 16465242 DOI: 10.1038/Sj.Cdd.4400249  0.498
2006 Zhong F, Davis MC, McColl KS, Distelhorst CW. Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation. The Journal of Cell Biology. 172: 127-37. PMID 16391001 DOI: 10.1083/Jcb.200506189  0.403
2006 Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, Distelhorst CW. Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis. Oncogene. 25: 1903-13. PMID 16301999 DOI: 10.1038/Sj.Onc.1209218  0.556
2006 Gomez JA, Gama V, Distelhorst C, Matsuyama S. Cell Penetrating Activity of Bax Inhibiting Peptides (BIPs) and Its Utilization for Protein Transduction. Blood. 108: 4239-4239. DOI: 10.1182/Blood.V108.11.4239.4239  0.4
2005 Gama V, Yoshida T, Cohen H, Sinclair D, Yokota T, Distelhorst C, Matsuyama S. Poly-Glutamine Induces Bax-Mediated Cell Death by Dissociating Ku70 from Bax through Ku70-Acetylation. Blood. 106: 4299-4299. DOI: 10.1182/Blood.V106.11.4299.4299  0.518
2005 Gomez JA, Yoshida T, Lam M, Distelhorst CW, Matsuyama S. Cell Penetrating Mechanism of Bax Inhibiting Peptides. Blood. 106: 4298-4298. DOI: 10.1182/Blood.V106.11.4298.4298  0.366
2004 Malone MH, Wang Z, Distelhorst CW. The glucocorticoid-induced gene tdag8 encodes a pro-apoptotic G protein-coupled receptor whose activation promotes glucocorticoid-induced apoptosis. The Journal of Biological Chemistry. 279: 52850-9. PMID 15485889 DOI: 10.1074/Jbc.M408040200  0.558
2004 Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, Velez P, Distelhorst CW. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. The Journal of Cell Biology. 166: 193-203. PMID 15263017 DOI: 10.1083/Jcb.200309146  0.361
2004 Distelhorst CW, Shore GC. Bcl-2 and calcium: controversy beneath the surface. Oncogene. 23: 2875-80. PMID 15077150 DOI: 10.1038/Sj.Onc.1207519  0.387
2003 Thomenius MJ, Distelhorst CW. Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance. Journal of Cell Science. 116: 4493-9. PMID 14576343 DOI: 10.1242/Jcs.00829  0.745
2003 Distelhorst CW, Roderick HL. Ins(1,4,5)P3-mediated calcium signals and apoptosis: Is there a role for Bcl-2? Biochemical Society Transactions. 31: 958-959. PMID 14505458 DOI: 10.1042/Bst0310958  0.456
2003 Wang Z, Malone MH, Thomenius MJ, Zhong F, Xu F, Distelhorst CW. Dexamethasone-induced gene 2 (dig2) is a novel pro-survival stress gene induced rapidly by diverse apoptotic signals. The Journal of Biological Chemistry. 278: 27053-8. PMID 12736248 DOI: 10.1074/Jbc.M303723200  0.732
2003 Demaurex N, Distelhorst C. Cell biology. Apoptosis--the calcium connection. Science (New York, N.Y.). 300: 65-7. PMID 12677047 DOI: 10.1126/Science.1083628  0.451
2003 Wang Z, Malone MH, He H, McColl KS, Distelhorst CW. Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. The Journal of Biological Chemistry. 278: 23861-7. PMID 12676946 DOI: 10.1074/Jbc.M301843200  0.541
2003 Thomenius MJ, Wang NS, Reineks EZ, Wang Z, Distelhorst CW. Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins. The Journal of Biological Chemistry. 278: 6243-50. PMID 12477729 DOI: 10.1074/Jbc.M208878200  0.745
2002 Distelhorst CW. Recent insights into the mechanism of glucocorticosteroid-induced apoptosis Cell Death and Differentiation. 9: 6-19. PMID 11803370 DOI: 10.1038/Sj.Cdd.4400969  0.536
2001 Wang NS, Unkila MT, Reineks EZ, Distelhorst CW. Transient Expression of Wild-type or Mitochondrially Targeted Bcl-2 Induces Apoptosis, whereas Transient Expression of Endoplasmic Reticulum-targeted Bcl-2 Is Protective against Bax-induced Cell Death Journal of Biological Chemistry. 276: 44117-44128. PMID 11546793 DOI: 10.1074/jbc.M101958200  0.49
2001 Unkila M, McColl KS, Thomenius MJ, Heiskanen K, Distelhorst CW. Unreliability of the cytochrome c-enhanced green fluorescent fusion protein as a marker of cytochrome c release in cells that overexpress Bcl-2. The Journal of Biological Chemistry. 276: 39132-7. PMID 11489892 DOI: 10.1074/jbc.M104986200  0.704
2001 He H, Malone M, Ostrowski S, Distelhorst C. Gene expression analysis of glucocorticoid-induced apoptosis by a gene microarray technique Nature Genetics. 27: 58-58. DOI: 10.1038/87108  0.368
2000 He H, Mccoll K, Distelhorst CW. Involvement of c-Fos in signaling grp78 induction following ER calcium release Oncogene. 19: 5936-5943. PMID 11127825 DOI: 10.1038/Sj.Onc.1203994  0.451
1998 He H, Qi XM, Grossmann J, Distelhorst CW. c-Fos degradation by the proteasome: An early, Bcl-2-regulated step in apoptosis Journal of Biological Chemistry. 273: 25015-25019. PMID 9737957 DOI: 10.1074/Jbc.273.39.25015  0.52
1998 McColl KS, He H, Zhong H, Whitacre CM, Berger NA, Distelhorst CW. Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activation. Molecular and Cellular Endocrinology. 139: 229-38. PMID 9705090 DOI: 10.1016/S0303-7207(98)00051-3  0.552
1998 Deak JC, Cross JV, Lewis M, Qian Y, Parrott LA, Distelhorst CW, Templeton DJ. Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1. Proceedings of the National Academy of Sciences of the United States of America. 95: 5595-600. PMID 9576928 DOI: 10.1073/Pnas.95.10.5595  0.396
1998 Distelhorst CW, Dubyak G. Role of calcium in glucocorticosteroid-induced apoptosis of thymocytes and lymphoma cells: Resurrection of old theories by new findings Blood. 91: 731-734. PMID 9446630 DOI: 10.1182/Blood.V91.3.731.731_731_734  0.463
1997 Qi XM, Simonson M, Distelhorst CW. Bcl-2 inhibits c-fos induction by calcium Oncogene. 15: 2849-2853. PMID 9419976 DOI: 10.1038/Sj.Onc.1201463  0.438
1997 He H, Lam M, McCormick TS, Distelhorst CW. Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl- 2 Journal of Cell Biology. 138: 1219-1228. PMID 9298978 DOI: 10.1083/Jcb.138.6.1219  0.465
1997 Qi XM, He H, Zhong H, Distelhorst CW. Baculovirus p35 and Z-VAD-fmk inhibit thapsigargin-induced apoptosis of breast cancer cells Oncogene. 15: 1207-1212. PMID 9294614 DOI: 10.1038/Sj.Onc.1201290  0.558
1997 Distelhorst CW. Glucocorticoid-Induced Apoptosis Advances in Pharmacology. 41: 247-270. PMID 9204148 DOI: 10.1016/S1054-3589(08)61061-3  0.42
1997 McCormick TS, McColl KS, Distelhorst CW. Mouse lymphoma cells destined to undergo apoptosis in response to thapsigargin treatment fail to generate a calcium-mediated grp78/grp94 stress response Journal of Biological Chemistry. 272: 6087-6092. PMID 9038234 DOI: 10.1074/Jbc.272.9.6087  0.528
1997 Lam M, Stallcup M, Distelhorst CW. Expression of a defective mouse mammary tumor virus envelope glycoprotein precursor which binds stably to GRP78 within the lumen of the endoplasmic reticulum is associated with decreased glucocorticoid-induced apoptosis in mouse lymphoma cells Cell Death and Differentiation. 4: 283-288.  0.409
1996 Distelhorst CW, McCormick TS. Bcl-2 acts subsequent to and independent of Ca2+ fluxes to inhibit apoptosis in thapsigargin and glucocorticoid treated mouse lymphoma cells Cell Calcium. 19: 473-483. PMID 8842514 DOI: 10.1016/S0143-4160(96)90056-1  0.433
1996 Distelhorst CW, Lam M, McCormick TS. Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion Oncogene. 12: 2051-2055. PMID 8668330  0.331
1996 Sobecks R, McCormick TS, Distelhorst CW. Imidazole antifungals Miconazole and Econazole induce apoptosis in mouse lymphoma and human T cell leukemia cells: Regulation by Bcl-2 and potential role of calcium Cell Death and Differentiation. 3: 331-337.  0.471
1994 Lam M, Dubyak G, Chen L, Nuñez G, Miesfeld RL, Distelhorst CW. Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes Proceedings of the National Academy of Sciences of the United States of America. 91: 6569-6573. PMID 8022822 DOI: 10.1073/Pnas.91.14.6569  0.49
1993 Lam M, Dubyak G, Distelhorst CW. Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells Molecular Endocrinology. 7: 686-693. PMID 8316252 DOI: 10.1210/Mend.7.5.8316252  0.377
1992 Schlatter LK, Howard KJ, Parker MG, Distelhorst CW. Comparison of the 90-kilodalton heat shock protein interaction with in vitro translated glucocorticoid and estrogen receptors Molecular Endocrinology. 6: 132-140. PMID 1738366 DOI: 10.1210/Mend.6.1.1738366  0.316
1992 Lam M, Vimmerstedt LJ, Schlatter LK, Hensold JO, Distelhorst CW. Preferential synthesis of the 78-Kd glucose-regulated protein in glucocorticoid-treated S49 mouse lymphoma cells Blood. 79: 3285-3292. PMID 1596569 DOI: 10.1182/Blood.V79.12.3285.Bloodjournal79123285  0.38
1990 Distelhorst CW, Howard KJ. Evidence from pulse-chase labeling studies that the antiglucocorticoid hormone RU486 stabilizes the nonactivated form of the glucocorticoid receptor in mouse lymphoma cells Journal of Steroid Biochemistry. 36: 25-31. PMID 2362447 DOI: 10.1016/0022-4731(90)90110-E  0.358
1989 Schneider SM, Distelhorst CW. Chemotherapy-induced emergencies Seminars in Oncology. 16: 572-578. PMID 2688116 DOI: 10.5555/Uri:Pii:0093775489900341  0.341
1988 Howard KJ, Distelhorst CW. Effect of the 90 kDa heat shock protein, HSP90, on glucocorticoid receptor binding to DNA-cellulose Biochemical and Biophysical Research Communications. 151: 1226-1232. PMID 3355552 DOI: 10.1016/S0006-291X(88)80497-2  0.316
1988 Distelhorst CW. Glucocorticosteroids induce DNA fragmentation in human lymphoid leukemia cells Blood. 72: 1305-1309. PMID 3262387 DOI: 10.1182/Blood.V72.4.1305.Bloodjournal7241305  0.319
1987 Distelhorst CW, Kullman L, Wasson J. Characterization of glucocorticoid receptors in S49 mouse lymphoma cells by affinity labeling with [3H]dexamethasone 21-mesylate Journal of Steroid Biochemistry. 26: 59-65. PMID 3821108 DOI: 10.1016/0022-4731(87)90031-8  0.327
1987 Distelhorst CW, Janiga KE, Howard KJ, Strandjord SE, Campbell EJ. Neutrophil elastase produces 52-kD and 30-kD glucocorticoid receptor fragments in the cytosol of human leukemia cells Blood. 70: 860-868. PMID 3304464 DOI: 10.1182/Blood.V70.3.860.Bloodjournal703860  0.384
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