Dahabada H. Lopes, Ph.D. - Publications

Affiliations: 
Neurology University of California, Los Angeles, Los Angeles, CA 
Area:
Type 2 diabetes, Drug development

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Koronyo-Hamaoui M, Sheyn J, Hayden EY, Li S, Fuchs DT, Regis GC, Lopes DHJ, Black KL, Bernstein KE, Teplow DB, Fuchs S, Koronyo Y, Rentsendorj A. Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease. Brain : a Journal of Neurology. PMID 31794021 DOI: 10.1093/brain/awz364  1
2015 Lopes DH, Attar A, Nair G, Hayden EY, Du Z, McDaniel K, Dutt S, Bravo-Rodriguez K, Mittal S, Klärner FG, Wang C, Sanchez-Garcia E, Schrader T, Bitan G. Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism. Acs Chemical Biology. 10: 1555-69. PMID 25844890 DOI: 10.1021/acschembio.5b00146  1
2014 Bernstein KE, Koronyo Y, Salumbides BC, Sheyn J, Pelissier L, Lopes DH, Shah KH, Bernstein EA, Fuchs DT, Yu JJ, Pham M, Black KL, Shen XZ, Fuchs S, Koronyo-Hamaoui M. Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline. The Journal of Clinical Investigation. 124: 1000-12. PMID 24487585 DOI: 10.1172/JCI66541  1
2013 Connors CR, Rosenman DJ, Lopes DH, Mittal S, Bitan G, Sorci M, Belfort G, Garcia A, Wang C. Tranilast binds to aβ monomers and promotes aβ fibrillation. Biochemistry. 52: 3995-4002. PMID 23679559 DOI: 10.1021/bi400426t  1
2012 Sinha S, Lopes DH, Bitan G. A key role for lysine residues in amyloid β-protein folding, assembly, and toxicity. Acs Chemical Neuroscience. 3: 473-81. PMID 22860216 DOI: 10.1021/cn3000247  1
2012 Lopes DH, Sinha S, Rosensweig C, Bitan G. Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins. Methods in Molecular Biology (Clifton, N.J.). 849: 11-21. PMID 22528080 DOI: 10.1007/978-1-61779-551-0_2  1
2012 Novick PA, Lopes DH, Branson KM, Esteras-Chopo A, Graef IA, Bitan G, Pande VS. Design of β-amyloid aggregation inhibitors from a predicted structural motif. Journal of Medicinal Chemistry. 55: 3002-10. PMID 22420626 DOI: 10.1021/jm201332p  1
2012 Li H, Zemel R, Lopes DH, Monien BH, Bitan G. A two-step strategy for structure-activity relationship studies of N-methylated aβ42 C-terminal fragments as aβ42 toxicity inhibitors. Chemmedchem. 7: 515-22. PMID 22307963 DOI: 10.1002/cmdc.201100584  1
2011 Li H, Du Z, Lopes DH, Fradinger EA, Wang C, Bitan G. C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42. Journal of Medicinal Chemistry. 54: 8451-60. PMID 22087474 DOI: 10.1021/jm200982p  1
2011 Moskovitz J, Maiti P, Lopes DH, Oien DB, Attar A, Liu T, Mittal S, Hayes J, Bitan G. Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo. Biochemistry. 50: 10687-97. PMID 22059533 DOI: 10.1021/bi201426b  1
2011 Sinha S, Lopes DH, Du Z, Pang ES, Shanmugam A, Lomakin A, Talbiersky P, Tennstaedt A, McDaniel K, Bakshi R, Kuo PY, Ehrmann M, Benedek GB, Loo JA, Klärner FG, et al. Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins. Journal of the American Chemical Society. 133: 16958-69. PMID 21916458 DOI: 10.1021/ja206279b  1
2007 Lopes DH, Meister A, Gohlke A, Hauser A, Blume A, Winter R. Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy. Biophysical Journal. 93: 3132-41. PMID 17660321 DOI: 10.1529/biophysj.107.110635  1
2007 Lopes D, Grudzielanek S, Vogtt K, Winter R. Towards an understanding of the temperature/ pressure configurational and free-energy landscape of biomolecules Journal of Non-Equilibrium Thermodynamics. 32: 41-97. DOI: 10.1515/JNETDY.2007.003  1
2004 Lopes DH, Chapeaurouge A, Manderson GA, Johansson JS, Ferreira ST. Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis. The Journal of Biological Chemistry. 279: 10991-6. PMID 14701847 DOI: 10.1074/jbc.M308174200  1
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