Eran Hornstein - Publications

Weizmann Institute of Science, Rehovot, Israel 
ALS, motor neuron, miRNA

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin JP, Allen S, Nezhad HG, Iacoangeli A, Yacovzada NY, Eitan C, Hornstein E, Elhaik E, Celadova P, Bose D, Farhan S, et al. Rare variant burden analysis within enhancers identifies CAV1 as an ALS risk gene. Cell Reports. 34: 108730. PMID 33535055 DOI: 10.1016/j.celrep.2021.108730  1
2020 Cooper-Knock J, Zhang S, Kenna KP, Moll T, Franklin JP, Allen S, Nezhad HG, Iacoangeli A, Yacovzada NY, Eitan C, Hornstein E, Ehilak E, Celadova P, Bose D, Farhan S, et al. Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene. Cell Reports. 33: 108456. PMID 33264630 DOI: 10.1016/j.celrep.2020.108456  1
2020 Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, ... ... Hornstein E, et al. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Molecular Cell. PMID 33217318 DOI: 10.1016/j.molcel.2020.10.032  1
2019 Reichenstein I, Eitan C, Diaz-Garcia S, Haim G, Magen I, Siany A, Hoye ML, Rivkin N, Olender T, Toth B, Ravid R, Mandelbaum AD, Yanowski E, Liang J, Rymer JK, ... ... Hornstein E, et al. Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology. Science Translational Medicine. 11. PMID 31852800 DOI: 10.1126/scitranslmed.aav5264  1
2019 Mandelbaum AD, Kredo-Russo S, Aronowitz D, Myers N, Yanowski E, Klochendler A, Swisa A, Dor Y, Hornstein E. miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice. Diabetologia. PMID 31187215 DOI: 10.1007/s00125-019-4916-z  1
2018 Coenen-Stass AML, Magen I, Brooks T, Ben-Dov IZ, Greensmith L, Hornstein E, Fratta P. Evaluation of methodologies for microRNA biomarker detection by next generation sequencing. Rna Biology. 1-13. PMID 30223713 DOI: 10.1080/15476286.2018.1514236  0.44
2018 Yardeni T, Fine R, Joshi Y, Gradus-Pery T, Kozer N, Reichenstein I, Yanowski E, Nevo S, Weiss-Tishler H, Eisenberg-Bord M, Shalit T, Plotnikov A, Barr HM, Perlson E, Hornstein E. High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria. Scientific Reports. 8: 59. PMID 29311649 DOI: 10.1038/s41598-017-17878-x  0.32
2017 Rivkin N, Chapnik E, Birger Y, Yanowski E, Curato C, Mildner A, Porat Z, Amir G, Izraeli S, Jung S, Hornstein E. Rac1 functions downstream of miR-142 in regulation of erythropoiesis. Haematologica. PMID 28912177 DOI: 10.3324/haematol.2017.171736  0.68
2017 Varol D, Mildner A, Blank T, Shemer A, Barashi N, Yona S, David E, Boura-Halfon S, Segal-Hayoun Y, Chappell-Maor L, Keren-Shaul H, Leshkowitz D, Hornstein E, Fuhrmann M, Amit I, et al. Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain. Immunity. 46: 1030-1044.e8. PMID 28636953 DOI: 10.1016/j.immuni.2017.05.003  0.52
2017 Mildner A, Chapnik E, Varol D, Aychek T, Lampl N, Rivkin N, Bringmann A, Paul F, Boura-Halfon S, Hayoun YS, Barnett-Itzhaki Z, Amit I, Hornstein E, Jung S. MicroRNA-142 controls thymocyte proliferation. European Journal of Immunology. PMID 28471480 DOI: 10.1002/eji.201746987  0.68
2017 Rotem N, Magen I, Ionescu A, Gershoni-Emek N, Altman T, Costa CJ, Gradus T, Pasmanik-Chor M, Willis DE, Ben-Dov IZ, Hornstein E, Perlson E. ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models. Scientific Reports. 7: 44500. PMID 28300211 DOI: 10.1038/srep44500  0.44
2016 Rivkin N, Chapnik E, Mildner A, Barshtein G, Porat Z, Kartvelishvily E, Dadosh T, Birger Y, Amir G, Yedgar S, Izraeli S, Jung S, Hornstein E. Erythrocyte survival is controlled by microRNA-142. Haematologica. PMID 27909218 DOI: 10.3324/haematol.2016.156109  0.68
2016 Eitan C, Hornstein E. Vulnerability of microRNA biogenesis in FTD-ALS. Brain Research. PMID 26778173 DOI: 10.1016/j.brainres.2015.12.063  1
2016 Eitan C, Hornstein E. Vulnerability of microRNA biogenesis in FTD-ALS Brain Research. DOI: 10.1016/j.brainres.2015.12.063  1
2015 Emde A, Eitan C, Liou LL, Libby RT, Rivkin N, Magen I, Reichenstein I, Oppenheim H, Eilam R, Silvestroni A, Alajajian B, Ben-Dov IZ, Aebischer J, Savidor A, Levin Y, ... ... Hornstein E, et al. Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS. The Embo Journal. 34: 2633-51. PMID 26330466 DOI: 10.15252/embj.201490493  1
2015 Nathan G, Kredo-Russo S, Geiger T, Lenz A, Kaspi H, Hornstein E, Efrat S. MiR-375 promotes redifferentiation of adult human β cells expanded in vitro. Plos One. 10: e0122108. PMID 25875172 DOI: 10.1371/journal.pone.0122108  1
2015 Eitan C, Hornstein E. Astro-logics with microRNAs. The Embo Journal. 34: 1143-4. PMID 25736376 DOI: 10.15252/embj.201591241  1
2014 Emde A, Hornstein E. miRNAs at the interface of cellular stress and disease. The Embo Journal. 33: 1428-37. PMID 24867813 DOI: 10.15252/embj.201488142  1
2014 Chapnik E, Rivkin N, Mildner A, Beck G, Pasvolsky R, Metzl-Raz E, Birger Y, Amir G, Tirosh I, Porat Z, Israel LL, Lellouche E, Michaeli S, Lellouche JP, Izraeli S, ... ... Hornstein E, et al. miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis. Elife. 3: e01964. PMID 24859754 DOI: 10.7554/eLife.01964  1
2014 Magen I, Hornstein E. Oligonucleotide-based therapy for neurodegenerative diseases. Brain Research. 1584: 116-28. PMID 24727531 DOI: 10.1016/j.brainres.2014.04.005  1
2014 Kaspi H, Pasvolsky R, Hornstein E. Could microRNAs contribute to the maintenance of β cell identity? Trends in Endocrinology and Metabolism: Tem. 25: 285-92. PMID 24656914 DOI: 10.1016/j.tem.2014.01.003  1
2013 Kaspi H, Chapnik E, Levy M, Beck G, Hornstein E, Soen Y. Brief report: miR-290-295 regulate embryonic stem cell differentiation propensities by repressing Pax6. Stem Cells (Dayton, Ohio). 31: 2266-72. PMID 23843298 DOI: 10.1002/stem.1465  1
2013 Mildner A, Chapnik E, Manor O, Yona S, Kim KW, Aychek T, Varol D, Beck G, Itzhaki ZB, Feldmesser E, Amit I, Hornstein E, Jung S. Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis. Blood. 121: 1016-27. PMID 23212522 DOI: 10.1182/blood-2012-07-445999  1
2012 Mandelbaum AD, Melkman-Zehavi T, Oren R, Kredo-Russo S, Nir T, Dor Y, Hornstein E. Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism. Experimental Diabetes Research. 2012: 470302. PMID 22991506 DOI: 10.1155/2012/470302  1
2012 Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E. Pancreas-enriched miRNA refines endocrine cell differentiation. Development (Cambridge, England). 139: 3021-31. PMID 22764048 DOI: 10.1242/dev.080127  1
2012 Kredo-Russo S, Ness A, Mandelbaum AD, Walker MD, Hornstein E. Regulation of pancreatic microRNA-7 expression. Experimental Diabetes Research. 2012: 695214. PMID 22675342 DOI: 10.1155/2012/695214  1
2012 Itkin T, Ludin A, Gradus B, Gur-Cohen S, Kalinkovich A, Schajnovitz A, Ovadya Y, Kollet O, Canaani J, Shezen E, Coffin DJ, Enikolopov GN, Berg T, Piacibello W, Hornstein E, et al. FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation. Blood. 120: 1843-55. PMID 22645180 DOI: 10.1182/blood-2011-11-394692  1
2012 Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E. Efficiency and specificity in microRNA biogenesis. Nature Structural & Molecular Biology. 19: 650-2. PMID 22580560 DOI: 10.1038/nsmb.2293  1
2012 Hornstein E. Understanding how miRNA genes function in metazoan development. Preface. Current Topics in Developmental Biology. 99: xi-xii. PMID 22365742 DOI: 10.1016/B978-0-12-387038-4.00016-1  1
2012 Chapnik E, Sasson V, Blelloch R, Hornstein E. Dgcr8 controls neural crest cells survival in cardiovascular development. Developmental Biology. 362: 50-6. PMID 22138056 DOI: 10.1016/j.ydbio.2011.11.008  1
2011 Haramati S, Navon I, Issler O, Ezra-Nevo G, Gil S, Zwang R, Hornstein E, Chen A. MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14191-203. PMID 21976504 DOI: 10.1523/JNEUROSCI.1673-11.2011  1
2011 Barad O, Hornstein E, Barkai N. Robust selection of sensory organ precursors by the Notch-Delta pathway. Current Opinion in Cell Biology. 23: 663-7. PMID 21963301 DOI: 10.1016/  1
2011 Gradus B, Alon I, Hornstein E. miRNAs control tracheal chondrocyte differentiation. Developmental Biology. 360: 58-65. PMID 21945074 DOI: 10.1016/j.ydbio.2011.09.002  1
2011 Goljanek-Whysall K, Sweetman D, Abu-Elmagd M, Chapnik E, Dalmay T, Hornstein E, Münsterberg A. MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 11936-41. PMID 21730146 DOI: 10.1073/pnas.1105362108  1
2011 Lerman G, Avivi C, Mardoukh C, Barzilai A, Tessone A, Gradus B, Pavlotsky F, Barshack I, Polak-Charcon S, Orenstein A, Hornstein E, Sidi Y, Avni D. MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R. Plos One. 6: e20916. PMID 21687694 DOI: 10.1371/journal.pone.0020916  1
2011 Kredo-Russo S, Hornstein E. MicroRNA knock down by cholesterol-conjugated antisense oligos in mouse organ culture. Methods in Molecular Biology (Clifton, N.J.). 732: 89-97. PMID 21431707 DOI: 10.1007/978-1-61779-083-6_7  1
2011 Melkman-Zehavi T, Oren R, Kredo-Russo S, Shapira T, Mandelbaum AD, Rivkin N, Nir T, Lennox KA, Behlke MA, Dor Y, Hornstein E. miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors. The Embo Journal. 30: 835-45. PMID 21285947 DOI: 10.1038/emboj.2010.361  1
2011 Biton M, Levin A, Slyper M, Alkalay I, Horwitz E, Mor H, Kredo-Russo S, Avnit-Sagi T, Cojocaru G, Zreik F, Bentwich Z, Poy MN, Artis D, Walker MD, Hornstein E, et al. Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nature Immunology. 12: 239-46. PMID 21278735 DOI: 10.1038/ni.1994  1
2011 Afek Y, Alon N, Barad O, Hornstein E, Barkai N, Bar-Joseph Z. A biological solution to a fundamental distributed computing problem. Science (New York, N.Y.). 331: 183-5. PMID 21233379 DOI: 10.1126/science.1193210  1
2010 Hornstein E. miRNA activity directs stem cell commitment to a particular fate. Cell Cycle (Georgetown, Tex.). 9: 4041-2. PMID 20935480 DOI: 10.4161/cc.9.20.13686  1
2010 Mann M, Barad O, Agami R, Geiger B, Hornstein E. miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate. Proceedings of the National Academy of Sciences of the United States of America. 107: 15804-9. PMID 20720163 DOI: 10.1073/pnas.0915022107  1
2010 Haramati S, Chapnik E, Sztainberg Y, Eilam R, Zwang R, Gershoni N, McGlinn E, Heiser PW, Wills AM, Wirguin I, Rubin LL, Misawa H, Tabin CJ, Brown R, Chen A, ... Hornstein E, et al. miRNA malfunction causes spinal motor neuron disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 13111-6. PMID 20616011 DOI: 10.1073/pnas.1006151107  1
2010 Barad O, Rosin D, Hornstein E, Barkai N. Error minimization in lateral inhibition circuits. Science Signaling. 3: ra51. PMID 20606215 DOI: 10.1126/scisignal.2000857  1
2009 Shomron N, Golan D, Hornstein E. An evolutionary perspective of animal microRNAs and their targets. Journal of Biomedicine & Biotechnology. 2009: 594738. PMID 19759918 DOI: 10.1155/2009/594738  1
2009 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB. MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proceedings of the National Academy of Sciences of the United States of America. 106: 7915-20. PMID 19416898 DOI: 10.1073/pnas.0812446106  1
2009 Avnit-Sagi T, Kantorovich L, Kredo-Russo S, Hornstein E, Walker MD. The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas. Plos One. 4: e5033. PMID 19343226 DOI: 10.1371/journal.pone.0005033  1
2007 Nielsen CB, Shomron N, Sandberg R, Hornstein E, Kitzman J, Burge CB. Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. Rna (New York, N.Y.). 13: 1894-910. PMID 17872505 DOI: 10.1261/rna.768207  1
2006 Hornstein E, Shomron N. Canalization of development by microRNAs. Nature Genetics. 38: S20-4. PMID 16736020 DOI: 10.1038/ng1803  1
2006 Drukker M, Katchman H, Katz G, Even-Tov Friedman S, Shezen E, Hornstein E, Mandelboim O, Reisner Y, Benvenisty N. Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Stem Cells (Dayton, Ohio). 24: 221-9. PMID 16109762 DOI: 10.1634/stemcells.2005-0188  1
2005 Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature. 438: 671-4. PMID 16319892 DOI: 10.1038/nature04138  1
2005 Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proceedings of the National Academy of Sciences of the United States of America. 102: 10898-903. PMID 16040801 DOI: 10.1073/pnas.0504834102  1
2005 Hornstein E, Tabin CJ. Developmental biology: asymmetrical threat averted. Nature. 435: 155-6. PMID 15889074 DOI: 10.1038/435155a  1
2004 Hornstein E, Benvenisty N. The "brainy side" of human embryonic stem cells. Journal of Neuroscience Research. 76: 169-73. PMID 15048914 DOI: 10.1002/jnr.20034  1
2002 Stolovich M, Tang H, Hornstein E, Levy G, Cohen R, Bae SS, Birnbaum MJ, Meyuhas O. Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation. Molecular and Cellular Biology. 22: 8101-13. PMID 12417714 DOI: 10.1128/MCB.22.23.8101-8113.2002  1
2001 Hornstein E, Tang H, Meyuhas O. Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs. Cold Spring Harbor Symposia On Quantitative Biology. 66: 477-84. PMID 12762050  1
2001 Tang H, Hornstein E, Stolovich M, Levy G, Livingstone M, Templeton D, Avruch J, Meyuhas O. Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation. Molecular and Cellular Biology. 21: 8671-83. PMID 11713299 DOI: 10.1128/MCB.21.24.8671-8683.2001  1
1999 Hornstein E, Harel H, Levy G, Meyuhas O. Overexpression of poly(A)-binding protein down-regulates the translation or the abundance of its own mRNA. Febs Letters. 457: 209-13. PMID 10471780 DOI: 10.1016/S0014-5793(99)01039-X  1
1999 Hornstein E, Git A, Braunstein I, Avni D, Meyuhas O. The expression of poly(A)-binding protein gene is translationally regulated in a growth-dependent fashion through a 5'-terminal oligopyrimidine tract motif. The Journal of Biological Chemistry. 274: 1708-14. PMID 9880551 DOI: 10.1074/jbc.274.3.1708  1
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