Don Cleveland, PhD - Publications

University of California, San Diego, La Jolla, CA 

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shoshani O, Bakker B, de Haan L, Tijhuis AE, Wang Y, Kim DH, Maldonado M, Demarest MA, Artates J, Zhengyu O, Mark A, Wardenaar R, Sasik R, Spierings DCJ, Vitre B, ... ... Cleveland DW, et al. Transient genomic instability drives tumorigenesis through accelerated clonal evolution. Genes & Development. PMID 34266887 DOI: 10.1101/gad.348319.121  0.315
2021 Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. Publisher Correction: Chromothripsis drives the evolution of gene amplification in cancer. Nature. PMID 33649505 DOI: 10.1038/s41586-021-03379-5  0.664
2020 Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. Chromothripsis drives the evolution of gene amplification in cancer. Nature. PMID 33361815 DOI: 10.1038/s41586-020-03064-z  0.714
2019 Huang Y, Lin L, Liu X, Ye S, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y, Zhang J, Yang Z, Liu X, Yang Z, Zang J, ... ... Cleveland DW, et al. BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Research. PMID 31201382 DOI: 10.1038/s41422-019-0178-z  0.315
2019 Ly P, Brunner SF, Shoshani O, Kim DH, Lan W, Pyntikova T, Flanagan AM, Behjati S, Page DC, Campbell PJ, Cleveland DW. Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements. Nature Genetics. PMID 30833795 DOI: 10.1038/S41588-019-0360-8  0.734
2019 Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nature Communications. 10: 175. PMID 30635586 DOI: 10.1038/S41467-018-08073-1  0.621
2018 Kim DH, Han JS, Ly P, Ye Q, McMahon MA, Myung K, Corbett KD, Cleveland DW. TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC. Nature Communications. 9: 4354. PMID 30341343 DOI: 10.1038/S41467-018-06774-1  0.745
2018 Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, ... ... Cleveland DW, et al. Chromosomal instability drives metastasis through a cytosolic DNA response. Nature. PMID 29342134 DOI: 10.1038/Nature25432  0.803
2017 Ly P, Cleveland DW. Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis. Trends in Cell Biology. PMID 28899600 DOI: 10.1016/j.tcb.2017.08.005  0.739
2017 Ly P, Cleveland DW. Interrogating cell division errors using random and chromosome-specific missegregation approaches. Cell Cycle (Georgetown, Tex.). 1-7. PMID 28650219 DOI: 10.1080/15384101.2017.1325047  0.743
2017 Guo LY, Allu PK, Zandarashvili L, McKinley KL, Sekulic N, Dawicki-McKenna JM, Fachinetti D, Logsdon GA, Jamiolkowski RM, Cleveland DW, Cheeseman IM, Black BE. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nature Communications. 8: 15775. PMID 28598437 DOI: 10.1038/Ncomms15775  0.581
2017 Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J, Cleveland DW, Da Cruz S. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 28357566 DOI: 10.1007/S00401-017-1698-6  0.785
2017 Nechemia-Arbely Y, Fachinetti D, Miga KH, Sekulic N, Soni GV, Kim DH, Wong AK, Lee AY, Nguyen K, Dekker C, Ren B, Black BE, Cleveland DW. Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points. The Journal of Cell Biology. PMID 28235947 DOI: 10.1083/Jcb.201608083  0.597
2017 Levine MS, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, Spierings DC, Lansdorp PM, Cleveland DW, Lambrechts D, Foijer F, Holland AJ. Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals. Developmental Cell. PMID 28132847 DOI: 10.1016/J.Devcel.2016.12.022  0.5
2017 Fachinetti D, Logsdon GA, Abdullah A, Selzer EB, Cleveland DW, Black BE. CENP-A Modifications on Ser68 and Lys124 Are Dispensable for Establishment, Maintenance, and Long-Term Function of Human Centromeres. Developmental Cell. 40: 104-113. PMID 28073008 DOI: 10.1016/J.Devcel.2016.12.014  0.637
2016 Ly P, Teitz LS, Kim DH, Shoshani O, Skaletsky H, Fachinetti D, Page DC, Cleveland DW. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nature Cell Biology. PMID 27918550 DOI: 10.1038/ncb3450  0.751
2016 Hoffmann S, Dumont M, Barra V, Ly P, Nechemia-Arbely Y, McMahon MA, Hervé S, Cleveland DW, Fachinetti D. CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly. Cell Reports. 17: 2394-2404. PMID 27880912 DOI: 10.1016/J.Celrep.2016.10.084  0.74
2015 Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW. Chronic centrosome amplification without tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: E6321-E6330. PMID 26578792 DOI: 10.1073/Pnas.1519388112  0.786
2015 Kulukian A, Holland AJ, Vitre B, Naik S, Cleveland DW, Fuchs E. Epidermal development, growth control, and homeostasis in the face of centrosome amplification. Proceedings of the National Academy of Sciences of the United States of America. 112: E6311-20. PMID 26578791 DOI: 10.1073/Pnas.1518376112  0.802
2015 Topham C, Tighe A, Ly P, Bennett A, Sloss O, Nelson L, Ridgway RA, Huels D, Littler S, Schandl C, Sun Y, Bechi B, Procter DJ, Sansom OJ, Cleveland DW, et al. MYC Is a Major Determinant of Mitotic Cell Fate. Cancer Cell. 28: 129-40. PMID 26175417 DOI: 10.1016/J.Ccell.2015.06.001  0.738
2015 Mitchell JC, Constable R, So E, Vance C, Scotter E, Glover L, Hortobagyi T, Arnold ES, Ling SC, McAlonis M, Da Cruz S, Polymenidou M, Tessarolo L, Cleveland DW, Shaw CE. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta Neuropathologica Communications. 3: 36. PMID 26108367 DOI: 10.1186/S40478-015-0212-4  0.783
2015 Fachinetti D, Han JS, McMahon MA, Ly P, Abdullah A, Wong AJ, Cleveland DW. DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function. Developmental Cell. 33: 314-27. PMID 25942623 DOI: 10.1016/J.Devcel.2015.03.020  0.729
2015 Holland AJ, Reis RM, Niessen S, Pereira C, Andres DA, Spielmann HP, Cleveland DW, Desai A, Gassmann R. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Molecular Biology of the Cell. 26: 1845-56. PMID 25808490 DOI: 10.1091/Mbc.E14-11-1560  0.579
2015 Holland AJ, Reis RM, Niessen S, Pereira C, Andres DA, Spielmann HP, Cleveland DW, Desai A, Gassmann R. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors Molecular Biology of the Cell. 26: 1845-1856. DOI: 10.1091/mbc.E14-11-1560)  0.488
2014 Holland AJ, Cleveland DW. Polo-like kinase 4 inhibition: a strategy for cancer therapy? Cancer Cell. 26: 151-3. PMID 25117704 DOI: 10.1016/J.Ccr.2014.07.017  0.472
2014 Bodor DL, Mata JF, Sergeev M, David AF, Salimian KJ, Panchenko T, Cleveland DW, Black BE, Shah JV, Jansen LE. The quantitative architecture of centromeric chromatin. Elife. 3: e02137. PMID 25027692 DOI: 10.7554/Elife.02137  0.714
2014 Vitre B, Gudimchuk N, Borda R, Kim Y, Heuser JE, Cleveland DW, Grishchuk EL. Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E. Molecular Biology of the Cell. 25: 2272-81. PMID 24920822 DOI: 10.1091/Mbc.E14-01-0698  0.621
2014 Mirzaa GM, Vitre B, Carpenter G, Abramowicz I, Gleeson JG, Paciorkowski AR, Cleveland DW, Dobyns WB, O'Driscoll M. Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism. Human Genetics. 133: 1023-39. PMID 24748105 DOI: 10.1007/S00439-014-1443-3  0.352
2014 Bodor DL, Mata JF, Sergeev M, David AF, Salimian KJ, Panchenko T, Cleveland DW, Black BE, Shah JV, Jansen LET. The quantitative architecture of centromeric chromatin Elife. 2014. DOI: 10.7554/eLife.02137  0.718
2013 Silk AD, Zasadil LM, Holland AJ, Vitre B, Cleveland DW, Weaver BA. Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors. Proceedings of the National Academy of Sciences of the United States of America. 110: E4134-41. PMID 24133140 DOI: 10.1073/Pnas.1317042110  0.811
2013 Gudimchuk N, Vitre B, Kim Y, Kiyatkin A, Cleveland DW, Ataullakhanov FI, Grishchuk EL. Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips. Nature Cell Biology. 15: 1079-88. PMID 23955301 DOI: 10.1038/Ncb2831  0.614
2013 Fachinetti D, Folco HD, Nechemia-Arbely Y, Valente LP, Nguyen K, Wong AJ, Zhu Q, Holland AJ, Desai A, Jansen LE, Cleveland DW. A two-step mechanism for epigenetic specification of centromere identity and function. Nature Cell Biology. 15: 1056-66. PMID 23873148 DOI: 10.1038/Ncb2805  0.566
2013 Han JS, Holland AJ, Fachinetti D, Kulukian A, Cetin B, Cleveland DW. Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. Molecular Cell. 51: 92-104. PMID 23791783 DOI: 10.1016/J.Molcel.2013.05.019  0.79
2013 Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, ... ... Cleveland DW, et al. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 101-6. PMID 23580138 DOI: 10.1007/S10577-013-9347-Y  0.71
2013 Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D, Kordasiewicz HB, McAlonis-Downes M, Platoshyn O, Parone PA, Da Cruz S, Clutario KM, Swing D, Tessarollo L, Marsala M, ... ... Cleveland DW, et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America. 110: E736-45. PMID 23382207 DOI: 10.1073/Pnas.1222809110  0.794
2012 Holland AJ, Fachinetti D, Zhu Q, Bauer M, Verma IM, Nigg EA, Cleveland DW. The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes & Development. 26: 2684-9. PMID 23249732 DOI: 10.1101/Gad.207027.112  0.518
2012 Holland AJ, Cleveland DW. The deubiquitinase USP44 is a tumor suppressor that protects against chromosome missegregation. The Journal of Clinical Investigation. 122: 4325-8. PMID 23187131 DOI: 10.1172/Jci68319  0.555
2012 Holland AJ, Fachinetti D, Han JS, Cleveland DW. Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 109: E3350-7. PMID 23150568 DOI: 10.1073/Pnas.1216880109  0.501
2012 Holland AJ, Cleveland DW. Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements. Nature Medicine. 18: 1630-8. PMID 23135524 DOI: 10.1038/Nm.2988  0.57
2012 Holland AJ, Cleveland DW. Losing balance: the origin and impact of aneuploidy in cancer. Embo Reports. 13: 501-14. PMID 22565320 DOI: 10.1038/Embor.2012.55  0.51
2012 Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW. Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metabolism. 15: 778-86. PMID 22560226 DOI: 10.1016/J.Cmet.2012.03.019  0.404
2012 Kolano A, Brunet S, Silk AD, Cleveland DW, Verlhac MH. Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proceedings of the National Academy of Sciences of the United States of America. 109: E1858-67. PMID 22552228 DOI: 10.1073/Pnas.1204686109  0.729
2012 Holland AJ, Fachinetti D, Da Cruz S, Zhu Q, Vitre B, Lince-Faria M, Chen D, Parish N, Verma IM, Bettencourt-Dias M, Cleveland DW. Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis. Molecular Biology of the Cell. 23: 1838-45. PMID 22456511 DOI: 10.1091/Mbc.E11-12-1043  0.548
2011 Vande Velde C, McDonald KK, Boukhedimi Y, McAlonis-Downes M, Lobsiger CS, Bel Hadj S, Zandona A, Julien JP, Shah SB, Cleveland DW. Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. Plos One. 6: e22031. PMID 21779368 DOI: 10.1371/Journal.Pone.0022031  0.662
2011 Black BE, Cleveland DW. Epigenetic centromere propagation and the nature of CENP-a nucleosomes. Cell. 144: 471-9. PMID 21335232 DOI: 10.1016/J.Cell.2011.02.002  0.608
2010 Black BE, Jansen LE, Foltz DR, Cleveland DW. Centromere identity, function, and epigenetic propagation across cell divisions. Cold Spring Harbor Symposia On Quantitative Biology. 75: 403-18. PMID 21467140 DOI: 10.1101/Sqb.2010.75.038  0.623
2010 Li Q, Vande Velde C, Israelson A, Xie J, Bailey AO, Dong MQ, Chun SJ, Roy T, Winer L, Yates JR, Capaldi RA, Cleveland DW, Miller TM. ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import. Proceedings of the National Academy of Sciences of the United States of America. 107: 21146-51. PMID 21078990 DOI: 10.1073/Pnas.1014862107  0.639
2010 Hatch EM, Kulukian A, Holland AJ, Cleveland DW, Stearns T. Cep152 interacts with Plk4 and is required for centriole duplication. The Journal of Cell Biology. 191: 721-9. PMID 21059850 DOI: 10.1083/Jcb.201006049  0.797
2010 Kim Y, Holland AJ, Lan W, Cleveland DW. Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell. 142: 444-55. PMID 20691903 DOI: 10.1016/J.Cell.2010.06.039  0.711
2010 Holland AJ, Lan W, Cleveland DW. Centriole duplication: A lesson in self-control. Cell Cycle (Georgetown, Tex.). 9: 2731-6. PMID 20647763 DOI: 10.4161/Cc.9.14.12184  0.549
2010 Gassmann R, Holland AJ, Varma D, Wan X, Civril F, Cleveland DW, Oegema K, Salmon ED, Desai A. Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes & Development. 24: 957-71. PMID 20439434 DOI: 10.1101/Gad.1886810  0.59
2010 Holland AJ, Lan W, Niessen S, Hoover H, Cleveland DW. Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. The Journal of Cell Biology. 188: 191-8. PMID 20100909 DOI: 10.1083/Jcb.200911102  0.529
2010 Gurden MD, Holland AJ, van Zon W, Tighe A, Vergnolle MA, Andres DA, Spielmann HP, Malumbres M, Wolthuis RM, Cleveland DW, Taylor SS. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. Journal of Cell Science. 123: 321-30. PMID 20053638 DOI: 10.1242/Jcs.062075  0.583
2009 Samoshkin A, Arnaoutov A, Jansen LE, Ouspenski I, Dye L, Karpova T, McNally J, Dasso M, Cleveland DW, Strunnikov A. Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. Plos One. 4: e6831. PMID 19714251 DOI: 10.1371/Journal.Pone.0006831  0.348
2009 Holland AJ, Cleveland DW. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nature Reviews. Molecular Cell Biology. 10: 478-87. PMID 19546858 DOI: 10.1038/Nrm2718  0.553
2009 Weaver BA, Cleveland DW. The role of aneuploidy in promoting and suppressing tumors. The Journal of Cell Biology. 185: 935-7. PMID 19528293 DOI: 10.1083/jcb.200905098  0.554
2009 Foltz DR, Jansen LE, Bailey AO, Yates JR, Bassett EA, Wood S, Black BE, Cleveland DW. Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP. Cell. 137: 472-84. PMID 19410544 DOI: 10.1016/J.Cell.2009.02.039  0.726
2009 Silk AD, Holland AJ, Cleveland DW. Requirements for NuMA in maintenance and establishment of mammalian spindle poles. The Journal of Cell Biology. 184: 677-90. PMID 19255246 DOI: 10.1083/Jcb.200810091  0.774
2009 Kulukian A, Han JS, Cleveland DW. Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding. Developmental Cell. 16: 105-17. PMID 19154722 DOI: 10.1016/J.Devcel.2008.11.005  0.8
2008 Weaver BA, Cleveland DW. The aneuploidy paradox in cell growth and tumorigenesis. Cancer Cell. 14: 431-3. PMID 19061834 DOI: 10.1016/J.Ccr.2008.11.011  0.589
2008 Weaver BA, Silk AD, Cleveland DW. Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 30: 453. PMID 18791276 DOI: 10.3233/Clo-2008-0445  0.73
2008 Holland AJ, Cleveland DW. Beyond genetics: surprising determinants of cell fate in antitumor drugs. Cancer Cell. 14: 103-5. PMID 18691543 DOI: 10.1016/J.Ccr.2008.07.010  0.444
2008 Jelluma N, Brenkman AB, McLeod I, Yates JR, Cleveland DW, Medema RH, Kops GJ. Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. Plos One. 3: e2415. PMID 18545697 DOI: 10.1371/journal.pone.0002415  0.326
2008 Kim Y, Heuser JE, Waterman CM, Cleveland DW. CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether. The Journal of Cell Biology. 181: 411-9. PMID 18443223 DOI: 10.1083/Jcb.200802189  0.619
2008 Vande Velde C, Miller TM, Cashman NR, Cleveland DW. Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 105: 4022-7. PMID 18296640 DOI: 10.1073/Pnas.0712209105  0.638
2008 Detmer SA, Vande Velde C, Cleveland DW, Chan DC. Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A. Human Molecular Genetics. 17: 367-75. PMID 17959936 DOI: 10.1093/hmg/ddm314  0.659
2007 Weaver BA, Cleveland DW. Aneuploidy: instigator and inhibitor of tumorigenesis. Cancer Research. 67: 10103-5. PMID 17974949 DOI: 10.1158/0008-5472.CAN-07-2266  0.603
2007 Bailey AO, Miller TM, Dong MQ, Vande Velde C, Cleveland DW, Yates JR. RCADiA: simple automation platform for comparative multidimensional protein identification technology. Analytical Chemistry. 79: 6410-8. PMID 17616168 DOI: 10.1021/Ac070585G  0.616
2007 Conde e Silva N, Black BE, Sivolob A, Filipski J, Cleveland DW, Prunell A. CENP-A-containing nucleosomes: easier disassembly versus exclusive centromeric localization. Journal of Molecular Biology. 370: 555-73. PMID 17524417 DOI: 10.1016/J.Jmb.2007.04.064  0.576
2007 Weaver BA, Cleveland DW. Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science (New York, N.Y.). 316: 982; author reply 98. PMID 17510348 DOI: 10.1126/science.1139523  0.588
2007 Rakhit R, Robertson J, Vande Velde C, Horne P, Ruth DM, Griffin J, Cleveland DW, Cashman NR, Chakrabartty A. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. Nature Medicine. 13: 754-9. PMID 17486090 DOI: 10.1038/Nm1559  0.661
2007 Black BE, Brock MA, Bédard S, Woods VL, Cleveland DW. An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 104: 5008-13. PMID 17360341 DOI: 10.1073/Pnas.0700390104  0.578
2007 Jansen LE, Black BE, Foltz DR, Cleveland DW. Propagation of centromeric chromatin requires exit from mitosis. The Journal of Cell Biology. 176: 795-805. PMID 17339380 DOI: 10.1083/Jcb.200701066  0.643
2007 Black BE, Jansen LE, Maddox PS, Foltz DR, Desai AB, Shah JV, Cleveland DW. Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Molecular Cell. 25: 309-22. PMID 17244537 DOI: 10.1016/J.Molcel.2006.12.018  0.609
2007 Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 11: 25-36. PMID 17189716 DOI: 10.1016/J.Ccr.2006.12.003  0.782
2007 Weaver BA, Cleveland DW. Does aneuploidy cause cancer? [Current Opinion in Cell Biology 2006, 18:658-667] (DOI:10.1016/ Current Opinion in Cell Biology. 19: 246. DOI: 10.1016/J.Ceb.2007.02.017  0.494
2006 Weaver BA, Cleveland DW. Does aneuploidy cause cancer? Current Opinion in Cell Biology. 18: 658-67. PMID 17046232 DOI: 10.1016/  0.593
2006 Boillée S, Vande Velde C, Cleveland DW. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron. 52: 39-59. PMID 17015226 DOI: 10.1016/j.neuron.2006.09.018  0.673
2006 Weaver BA, Silk AD, Cleveland DW. Cell biology: nondisjunction, aneuploidy and tetraploidy. Nature. 442: E9-10; discussion E1. PMID 16915240 DOI: 10.1038/Nature05139  0.782
2006 Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR, Cleveland DW. The human CENP-A centromeric nucleosome-associated complex. Nature Cell Biology. 8: 458-69. PMID 16622419 DOI: 10.1038/Ncb1397  0.62
2005 Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: aneuploidy and the mitotic checkpoint. Nature Reviews. Cancer. 5: 773-85. PMID 16195750 DOI: 10.1038/nrc1714  0.609
2005 Mao Y, Desai A, Cleveland DW. Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. The Journal of Cell Biology. 170: 873-80. PMID 16144904 DOI: 10.1083/Jcb.200505040  0.491
2005 Weaver BA, Cleveland DW. Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell. 8: 7-12. PMID 16023594 DOI: 10.1016/j.ccr.2005.06.011  0.584
2005 Kops GJ, Kim Y, Weaver BA, Mao Y, McLeod I, Yates JR, Tagaya M, Cleveland DW. ZW10 links mitotic checkpoint signaling to the structural kinetochore. The Journal of Cell Biology. 169: 49-60. PMID 15824131 DOI: 10.1083/Jcb.200411118  0.757
2005 Vande Velde C, Cleveland DW. VEGF: multitasking in ALS. Nature Neuroscience. 8: 5-7. PMID 15622408 DOI: 10.1038/nn0105-5  0.605
2004 Vande Velde C, Garcia ML, Yin X, Trapp BD, Cleveland DW. The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease. Neuromolecular Medicine. 5: 193-203. PMID 15626820 DOI: 10.1385/NMM:5:3:193  0.658
2004 Wang H, Hu X, Ding X, Dou Z, Yang Z, Shaw AW, Teng M, Cleveland DW, Goldberg ML, Niu L, Yao X. Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. The Journal of Biological Chemistry. 279: 54590-8. PMID 15485811 DOI: 10.1074/Jbc.M407588200  0.343
2004 Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, et al. A standardized kinesin nomenclature. The Journal of Cell Biology. 167: 19-22. PMID 15479732 DOI: 10.1083/Jcb.200408113  0.393
2004 Black BE, Foltz DR, Chakravarthy S, Luger K, Woods VL, Cleveland DW. Structural determinants for generating centromeric chromatin. Nature. 430: 578-82. PMID 15282608 DOI: 10.1038/Nature02766  0.581
2004 Liu J, Lillo C, Jonsson PA, Vande Velde C, Ward CM, Miller TM, Subramaniam JR, Rothstein JD, Marklund S, Andersen PM, Brännström T, Gredal O, Wong PC, Williams DS, Cleveland DW. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron. 43: 5-17. PMID 15233913 DOI: 10.1016/J.Neuron.2004.06.016  0.658
2003 Yamanaka K, Vande Velde C, Eymard-Pierre E, Bertini E, Boespflug-Tanguy O, Cleveland DW. Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 16041-6. PMID 14668431 DOI: 10.1073/Pnas.2635267100  0.678
2003 Weaver BA, Bonday ZQ, Putkey FR, Kops GJ, Silk AD, Cleveland DW. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. The Journal of Cell Biology. 162: 551-63. PMID 12925705 DOI: 10.1083/Jcb.200303167  0.777
2003 Mao Y, Abrieu A, Cleveland DW. Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell. 114: 87-98. PMID 12859900 DOI: 10.1016/S0092-8674(03)00475-6  0.458
2003 Cleveland DW, Mao Y, Sullivan KF. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell. 112: 407-21. PMID 12600307 DOI: 10.1016/S0092-8674(03)00115-6  0.528
2002 Putkey FR, Cramer T, Morphew MK, Silk AD, Johnson RS, McIntosh JR, Cleveland DW. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Developmental Cell. 3: 351-65. PMID 12361599 DOI: 10.1016/S1534-5807(02)00255-1  0.792
2000 Price DL, Wong PC, Markowska AL, Lee MK, Thinakaren G, Cleveland DW, Sisodia SS, Borchelt DR. The value of transgenic models for the study of neurodegenerative diseases. Annals of the New York Academy of Sciences. 920: 179-91. PMID 11193148 DOI: 10.1111/J.1749-6632.2000.Tb06920.X  0.473
2000 Pasinelli P, Houseweart MK, Brown RH, Cleveland DW. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 13901-6. PMID 11095709 DOI: 10.1073/Pnas.240305897  0.768
2000 Yao X, Abrieu A, Zheng Y, Sullivan KF, Cleveland DW. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nature Cell Biology. 2: 484-91. PMID 10934468 DOI: 10.1038/35019518  0.313
2000 Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, Philp AV. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. The Journal of Cell Biology. 150: 1-11. PMID 10893249 DOI: 10.1083/Jcb.150.1.1  0.332
2000 Merdes A, Heald R, Samejima K, Earnshaw WC, Cleveland DW. Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. The Journal of Cell Biology. 149: 851-62. PMID 10811826 DOI: 10.1083/Jcb.149.4.851  0.654
1999 Houseweart MK, Cleveland DW. Cytoskeletal linkers: new MAPs for old destinations. Current Biology : Cb. 9: R864-6. PMID 10574751 DOI: 10.1016/S0960-9822(00)80048-2  0.775
1999 Houseweart MK, Cleveland DW. Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6446-56. PMID 10414973 DOI: 10.1523/Jneurosci.19-15-06446.1999  0.781
1998 Pasinelli P, Borchelt DR, Houseweart MK, Cleveland DW, Brown RH. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 15763-8. PMID 9861044 DOI: 10.1073/Pnas.95.26.15763  0.776
1998 Rao MV, Houseweart MK, Williamson TL, Crawford TO, Folmer J, Cleveland DW. Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation. The Journal of Cell Biology. 143: 171-81. PMID 9763429 DOI: 10.1083/Jcb.143.1.171  0.762
1998 Bruijn LI, Houseweart MK, Kato S, Anderson KL, Anderson SD, Ohama E, Reaume AG, Scott RW, Cleveland DW. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science (New York, N.Y.). 281: 1851-4. PMID 9743498 DOI: 10.1126/Science.281.5384.1851  0.78
1998 Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiology of Disease. 5: 27-35. PMID 9702785 DOI: 10.1006/Nbdi.1998.0178  0.472
1998 Houseweart MK, Cleveland DW. Intermediate filaments and their associated proteins: multiple dynamic personalities. Current Opinion in Cell Biology. 10: 93-101. PMID 9484600 DOI: 10.1016/S0955-0674(98)80091-4  0.781
1998 Merdes A, Cleveland DW. The role of NuMA in the interphase nucleus. Journal of Cell Science. 111: 71-9. PMID 9394013  0.637
1997 Yao X, Anderson KL, Cleveland DW. The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. The Journal of Cell Biology. 139: 435-47. PMID 9334346 DOI: 10.1083/jcb.139.2.435  0.311
1997 Merdes A, Cleveland DW. Pathways of spindle pole formation: different mechanisms; conserved components. The Journal of Cell Biology. 138: 953-6. PMID 9281574 DOI: 10.1083/Jcb.138.5.953  0.636
1997 Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron. 18: 327-38. PMID 9052802 DOI: 10.1016/S0896-6273(00)80272-X  0.491
1996 Price DL, Borchelt DR, Wong PC, Pardo CA, Thinakaran G, Lee MK, Cleveland DW, Sisodia SS. Neurodegenerative diseases and model systems. Cold Spring Harbor Symposia On Quantitative Biology. 61: 725-38. PMID 9246498 DOI: 10.1101/Sqb.1996.061.01.072  0.376
1996 Merdes A, Ramyar K, Vechio JD, Cleveland DW. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 87: 447-58. PMID 8898198 DOI: 10.1016/S0092-8674(00)81365-3  0.663
1996 Price DL, Koliatsos VE, Wong PC, Pardo CA, Borchelt DR, Lee MK, Cleveland DW, Griffin JW, Hoffman PN, Cork LC, Sisodia SS. Motor neuron disease and model systems: aetiologies, mechanisms and therapies. Ciba Foundation Symposium. 196: 3-13; discussion 13-. PMID 8866125  0.476
1996 Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology. 47: S54-61; discussion S. PMID 8858052 DOI: 10.1212/Wnl.47.4_Suppl_2.54S  0.488
1996 Brown KD, Wood KW, Cleveland DW. The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. Journal of Cell Science. 109: 961-9. PMID 8743943  0.324
1995 Pardo CA, Xu Z, Borchelt DR, Price DL, Sisodia SS, Cleveland DW. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proceedings of the National Academy of Sciences of the United States of America. 92: 954-8. PMID 7862672 DOI: 10.1073/Pnas.92.4.954  0.469
1995 Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu ZS, Sisodia SS, Price DL, Cleveland DW. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of Biological Chemistry. 270: 3234-8. PMID 7852409 DOI: 10.1074/Jbc.270.7.3234  0.477
1995 Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14: 1105-16. PMID 7605627 DOI: 10.1016/0896-6273(95)90259-7  0.493
1994 Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu ZS, Wong PC, Brown RH, Price DL, Sisodia SS, Cleveland DW. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proceedings of the National Academy of Sciences of the United States of America. 91: 8292-6. PMID 8058797 DOI: 10.1073/Pnas.91.17.8292  0.463
1994 Compton DA, Cleveland DW. NuMA, a nuclear protein involved in mitosis and nuclear reformation. Current Opinion in Cell Biology. 6: 343-6. PMID 7917323 DOI: 10.1016/0955-0674(94)90024-8  0.606
1991 Zhou R, Oskarsson M, Paules RS, Schulz N, Cleveland D, Woude GFV. Ability of the c-mos product to associate with and phosphorylate tubulin. Science. 251: 671-675. PMID 1825142 DOI: 10.1126/Science.1825142  0.343
1990 Sisodia SS, Gay DA, Cleveland DW. In vivo discrimination among beta-tubulin isotypes: selective degradation of a type IV beta-tubulin isotype following overexpression in cultured animal cells. The New Biologist. 2: 66-76. PMID 2078553  0.433
1989 Gay DA, Sisodia SS, Cleveland DW. Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation. Proceedings of the National Academy of Sciences of the United States of America. 86: 5763-7. PMID 2762294 DOI: 10.1073/Pnas.86.15.5763  0.447
1987 Sisodia SS, Sollner-Webb B, Cleveland DW. Specificity of RNA maturation pathways: RNAs transcribed by RNA polymerase III are not substrates for splicing or polyadenylation. Molecular and Cellular Biology. 7: 3602-12. PMID 3683396 DOI: 10.1128/mcb.7.10.3602-3612.1987  0.388
1987 Gabriel A, Sisodia SS, Cleveland DW. Evidence of discontinuous transcription in the trypanosomatid Crithidia fasciculata. The Journal of Biological Chemistry. 262: 16192-9. PMID 3680249  0.442
1987 Sisodia SS, Cleveland DW, Sollner-Webb B. A combination of RNase H and S1 nuclease circumvents an artefact inherent to conventional S1 analysis of RNA splicing. Nucleic Acids Research. 15: 1995-2011. PMID 3031584 DOI: 10.1093/nar/15.5.1995  0.4
1982 Cleveland D, Kirschner M. Autoregulatory control of the expression of α- and β-tubulins: Implications for microtubule assembly Cold Spring Harbor Symposia On Quantitative Biology. 46: 171-183. PMID 6286212 DOI: 10.1101/Sqb.1982.046.01.020  0.501
1981 Valenzuela P, Quiroga M, Zaldivar J, Rutter WJ, Kirschner MW, Cleveland DW. Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs. Nature. 289: 650-5. PMID 7464932 DOI: 10.1038/289650A0  0.375
1981 Cleveland DW, Hughes SH, Stubblefield E, Kirschner MW, Varmus HE. Multiple alpha and beta tubulin genes represent unlinked and dispersed gene families. The Journal of Biological Chemistry. 256: 3130-4. PMID 6259149  0.454
1981 Cleveland DW, Lopata MA, Sherline P, Kirschner MW. Unpolymerized tubulin modulates the level of tubulin mRNAs. Cell. 25: 537-46. PMID 6116546 DOI: 10.1016/0092-8674(81)90072-6  0.45
1980 Cleveland DW, Lopata MA, MacDonald RJ, Cowan NJ, Rutter WJ, Kirschner MW. Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell. 20: 95-105. PMID 6893015 DOI: 10.1016/0092-8674(80)90238-X  0.421
1980 Sánchez F, Natzle JE, Cleveland DW, Kirschner MW, McCarthy BJ. A dispersed multigene family encoding tubulin in Drosophila melanogaster. Cell. 22: 845-54. PMID 6780200 DOI: 10.1016/0092-8674(80)90561-9  0.414
1979 Cleveland DW, Spiegelman BM, Kirschner MW. Conservation of microtubule associated proteins. Isolation and characterization of tau and the high molecular weight microtubule associated protein from chicken brain and from mouse fibroblasts and comparison to the corresponding mammalian brain proteins. The Journal of Biological Chemistry. 254: 12670-8. PMID 227904  0.574
1978 Cleveland DW, Kirschner MW, Cowan NJ. Isolation of separate mRNAs for alpha- and beta-tubulin and characterization of the corresponding in vitro translation products. Cell. 15: 1021-31. PMID 728983 DOI: 10.1016/0092-8674(78)90286-6  0.408
1978 Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW. Intracellular localization of the high molecular weight microtubule accessory protein by indirect immunofluorescence. The Journal of Cell Biology. 76: 781-6. PMID 344329 DOI: 10.1083/Jcb.76.3.781  0.462
1977 Cleveland DW, Hwo SY, Kirschner MW. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. Journal of Molecular Biology. 116: 207-25. PMID 599557 DOI: 10.1016/0022-2836(77)90213-3  0.477
1977 Connolly JA, Kalnins VI, Cleveland DW, Kirschner MW. Immunoflourescent staining of cytoplasmic and spindle microtubules in mouse fibroblasts with antibody to tau protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 2437-40. PMID 329285 DOI: 10.1073/Pnas.74.6.2437  0.466
1977 Cleveland DW, Fischer SG, Kirschner MW, Laemmli UK. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. The Journal of Biological Chemistry. 252: 1102-6. PMID 320200  0.376
1977 Cleveland DW, Hwo SY, Kirschner MW. Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. Journal of Molecular Biology. 116: 227-47. PMID 146092 DOI: 10.1016/0022-2836(77)90214-5  0.461
1976 Witman GB, Cleveland DW, Weingarten MD, Kirschner MW. Tubulin requires tau for growth onto microtubule initiating sites. Proceedings of the National Academy of Sciences of the United States of America. 73: 4070-4. PMID 1069293 DOI: 10.1073/Pnas.73.11.4070  0.47
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