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Philip C. Wong, PhD - Publications

Affiliations: 
Pathology Johns Hopkins University, Baltimore, MD 
Area:
molecular mechanisms of neurodegenerative diseases
Website:
http://www.alzresearch.org/team.cfm?ID=29
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Year Citation  Score
2024 Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Kotha S, Kuo G, Katakam S, Jeong D, Wang L, Wang A, Chen R, ... ... Wong PC, et al. Lymphocyte-Activation Gene 3 Facilitates Pathological Tau Neuron-to-Neuron Transmission. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2303775. PMID 38327094 DOI: 10.1002/advs.202303775  0.307
2023 Chang K, Ling JP, Redding-Ochoa J, An Y, Li L, Dean SA, Blanchard TG, Pylyukh T, Barrett A, Irwin KE, Moghekar A, Resnick SM, Wong PC, Troncoso JC. Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline. Acta Neuropathologica. 147: 4. PMID 38133681 DOI: 10.1007/s00401-023-02653-2  0.581
2023 Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Katakam S, Jeong D, Wang L, Wang A, Chen R, Zhang S, Jin L, ... ... Wong PC, et al. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. Biorxiv : the Preprint Server For Biology. PMID 37293032 DOI: 10.1101/2023.05.16.541015  0.308
2023 Carmen-Orozco RP, Tsao W, Ye Y, Sinha IR, Chang K, Trinh V, Chung W, Bowden K, Troncoso JC, Blackshaw S, Hayes LR, Sun S, Wong PC, Ling JP. Elevated nuclear TDP-43 induces constitutive exon skipping. Biorxiv : the Preprint Server For Biology. PMID 37215013 DOI: 10.1101/2023.05.11.540291  0.694
2023 Irwin KE, Jasin P, Braunstein KE, Sinha I, Bowden KD, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Berry JD, Traynor B, Ling JP, Wong PC. A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS. Biorxiv : the Preprint Server For Biology. PMID 36789434 DOI: 10.1101/2023.01.23.525202  0.581
2022 Kim DW, Tu KJ, Wei A, Lau AJ, Gonzalez-Gil A, Cao T, Braunstein K, Ling JP, Troncoso JC, Wong PC, Blackshaw S, Schnaar RL, Li T. Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes. Molecular Neurodegeneration. 17: 83. PMID 36536457 DOI: 10.1186/s13024-022-00589-x  0.703
2022 Britson KA, Ling JP, Braunstein KE, Montagne JM, Kastenschmidt JM, Wilson A, Ikenaga C, Tsao W, Pinal-Fernandez I, Russell KA, Reed N, Mozaffar T, Wagner KR, Ostrow LW, Corse AM, ... ... Wong PC, et al. Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis. Science Translational Medicine. 14: eabi9196. PMID 35044790 DOI: 10.1126/scitranslmed.abi9196  0.566
2022 Islam S, Sun Y, Gao Y, Nakamura T, Noorani AA, Li T, Wong PC, Kimura N, Matsubara E, Kasuga K, Ikeuchi T, Tomita T, Zou K, Michikawa M. Presenilin is essential for ApoE secretion, a novel role of presenilin involved in Alzheimer's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34987110 DOI: 10.1523/JNEUROSCI.2039-21.2021  0.31
2020 Sieverding K, Ulmer J, Bruno C, Satoh T, Tsao W, Freischmidt A, Akira S, Wong PC, Ludolph AC, Danzer KM, Lobsiger CS, Brenner D, Weishaupt JH. Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43 transgenic mice. Experimental Neurology. 113496. PMID 33038415 DOI: 10.1016/j.expneurol.2020.113496  0.333
2020 Chen L, Wei Z, Chan KW, Li Y, Suchal K, Bi S, Huang J, Xu X, Wong PC, Lu H, van Zijl PC, Li T, Xu J. D-Glucose uptake and clearance in the tauopathy Alzheimer's disease mouse brain detected by on-resonance variable delay multiple pulse MRI. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20941264. PMID 32669023 DOI: 10.1177/0271678X20941264  0.34
2019 Donde A, Sun M, Ling JP, Braunstein KE, Pang B, Wen X, Cheng X, Chen L, Wong PC. Splicing repression is a major function of TDP-43 in motor neurons. Acta Neuropathologica. PMID 31332509 DOI: 10.1007/S00401-019-02042-8  0.644
2019 Donde A, Sun M, Jeong YH, Wen X, Ling J, Lin S, Braunstein K, Nie S, Wang S, Chen L, Wong PC. Upregulation of ATG7 Attenuates Motor Neuron Dysfunction Associated with Depletion of TARDBP/TDP-43. Autophagy. PMID 31242080 DOI: 10.1080/15548627.2019.1635379  0.737
2018 Chen L, Wei Z, Chan K, Cai S, Liu G, Lu H, Wong PC, van Zijl PCM, Li T, Xu J. Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI. Neuroimage. PMID 30553917 DOI: 10.1016/J.Neuroimage.2018.12.018  0.324
2017 Wiesner D, Tar L, Linkus B, Chandrasekar A, Heuvel FO, Dupuis L, Tsao W, Wong PC, Ludolph A, Roselli F. Reversible induction of TDP-43 granules in cortical neurons after traumatic injury. Experimental Neurology. PMID 28941811 DOI: 10.1016/J.Expneurol.2017.09.011  0.394
2017 Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL. Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43. Acta Neuropathologica. PMID 28332094 DOI: 10.1007/S00401-017-1701-2  0.638
2017 Jeong YH, Ling JP, Lin SZ, Donde AN, Braunstein KE, Majounie E, Traynor BJ, LaClair KD, Lloyd TE, Wong PC. Tdp-43 cryptic exons are highly variable between cell types. Molecular Neurodegeneration. 12: 13. PMID 28153034 DOI: 10.1186/S13024-016-0144-X  0.712
2016 Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S, Blackshaw S. An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks. Current Biology : Cb. PMID 28017605 DOI: 10.1016/J.Cub.2016.11.008  0.659
2016 Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, ... Wong PC, et al. Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 27834214 DOI: 10.1073/Pnas.1608432113  0.465
2016 LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathologica. PMID 27785573 DOI: 10.1007/S00401-016-1637-Y  0.665
2016 Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons. Cell Reports. 17: 104-13. PMID 27681424 DOI: 10.1016/J.Celrep.2016.08.071  0.597
2016 Li T, Braunstein KE, Zhang J, Lau A, Sibener L, Deeble C, Wong PC. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nature Communications. 7: 12082. PMID 27373369 DOI: 10.1038/Ncomms12082  0.404
2016 El Oussini H, Bayer H, Scekic-Zahirovic J, Vercruysse P, Sinniger J, Dirrig-Grosch S, Dieterlé S, Echaniz-Laguna A, Larmet Y, Müller K, Weishaupt JH, Thal DR, van Rheenen W, van Eijk K, Lawson R, ... ... Wong PC, et al. Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 26744351 DOI: 10.1007/S00401-016-1534-4  0.352
2016 Melnikova T, Shyam R, Porter S, LaClair K, Park D, Moghekar A, Farah M, Wong PC, Savonenko A. G-Secretase Modulator Enhances The Ab-Lowering Effect Of Bace1 Inhibitor In Mouse Models Of Alzheimer’S Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.719  0.308
2015 Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11346-57. PMID 26269641 DOI: 10.1523/Jneurosci.5289-14.2015  0.626
2015 Ling JP, Pletnikova O, Troncoso JC, Wong PC. NEURODEGENERATION. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science (New York, N.Y.). 349: 650-5. PMID 26250685 DOI: 10.1126/Science.Aab0983  0.616
2015 Heiman-Patterson TD, Blankenhorn EP, Sher RB, Jiang J, Welsh P, Dixon MC, Jeffrey JI, Wong P, Cox GA, Alexander GM. Genetic background effects on disease onset and lifespan of the mutant dynactin p150Glued mouse model of motor neuron disease. Plos One. 10: e0117848. PMID 25763819 DOI: 10.1371/Journal.Pone.0117848  0.328
2015 Wiesner D, Sinniger J, Henriques A, Dieterlé S, Müller HP, Rasche V, Ferger B, Dirrig-Grosch S, Soylu-Kucharz R, Petersén A, Walther P, Linkus B, Kassubek J, Wong PC, Ludolph AC, et al. Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration. Human Molecular Genetics. 24: 2228-40. PMID 25552654 DOI: 10.1093/Hmg/Ddu741  0.379
2015 Ling JP, Pletnikova O, Troncoso JC, Wong PC. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD Science. 349: 650-655. DOI: 10.1126/science.aab0983  0.576
2014 Vassar R, Kuhn PH, Haass C, Kennedy ME, Rajendran L, Wong PC, Lichtenthaler SF. Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects. Journal of Neurochemistry. 130: 4-28. PMID 24646365 DOI: 10.1111/Jnc.12715  0.421
2014 Wang H, Megill A, Wong PC, Kirkwood A, Lee HK. Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice. Plos One. 9: e92279. PMID 24637500 DOI: 10.1371/Journal.Pone.0092279  0.632
2014 Savonenko AV, Melnikova T, Li T, Price DL, Wong PC. Alzheimer Disease Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders. 321-338. DOI: 10.1016/B978-0-12-398270-4.00021-5  0.566
2013 Haidet-Phillips AM, Gross SK, Williams T, Tuteja A, Sherman A, Ko M, Jeong YH, Wong PC, Maragakis NJ. Altered astrocytic expression of TDP-43 does not influence motor neuron survival. Experimental Neurology. 250: 250-9. PMID 24120466 DOI: 10.1016/J.Expneurol.2013.10.004  0.373
2013 LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice. Molecular Neurodegeneration. 8: 18. PMID 23764200 DOI: 10.1186/1750-1326-8-18  0.395
2013 Stockmann M, Meyer-Ohlendorf M, Achberger K, Putz S, Demestre M, Yin H, Hendrich C, Linta L, Heinrich J, Brunner C, Proepper C, Kuh GF, Baumann B, Langer T, Schwalenstöcker B, ... ... Wong PC, et al. The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian syndromes. Journal of Neural Transmission (Vienna, Austria : 1996). 120: 785-98. PMID 23143281 DOI: 10.1007/S00702-012-0910-Z  0.371
2012 Tsao W, Jeong YH, Lin S, Ling J, Price DL, Chiang PM, Wong PC. Rodent models of TDP-43: recent advances. Brain Research. 1462: 26-39. PMID 22608070 DOI: 10.1016/J.Brainres.2012.04.031  0.776
2012 Savonenko AV, Melnikova T, Hiatt A, Li T, Worley PF, Troncoso JC, Wong PC, Price DL. Alzheimer's therapeutics: translation of preclinical science to clinical drug development. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 261-77. PMID 21937983 DOI: 10.1038/Npp.2011.211  0.508
2012 Chiang PM, Fortna RR, Price DL, Li T, Wong PC. Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin. Neurobiology of Aging. 33: 277-85. PMID 20382452 DOI: 10.1016/J.Neurobiolaging.2009.12.028  0.576
2012 Price DL, Savonenko AV, Li T, Wong PC. Alzheimer’s disease Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders. 149-167. DOI: 10.1017/CBO9780511980053.009  0.533
2012 Wong PC, Savonenko A, Li T, Price DL. Neurobiology of Alzheimer's Disease Basic Neurochemistry. 815-828. DOI: 10.1016/B978-0-12-374947-5.00046-8  0.559
2012 Wong PC, Chiang PM, Martin LJ, Koliatsos V, Price DL. Motor Neuron Diseases Basic Neurochemistry. 801-814. DOI: 10.1016/B978-0-12-374947-5.00045-6  0.564
2011 Li T, Li YM, Ahn K, Price DL, Sisodia SS, Wong PC. Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo. Plos One. 6: e28179. PMID 22140537 DOI: 10.1371/Journal.Pone.0028179  0.634
2011 Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, ... Wong PC, et al. Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation. Cell. 147: 615-28. PMID 22036569 DOI: 10.1016/J.Cell.2011.09.036  0.587
2011 Farah MH, Pan BH, Hoffman PN, Ferraris D, Tsukamoto T, Nguyen T, Wong PC, Price DL, Slusher BS, Griffin JW. Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5744-54. PMID 21490216 DOI: 10.1523/Jneurosci.6810-10.2011  0.562
2011 Tomita T, Wong PC. Selectivity to amyloid-β precursor protein cleavage provides hope against Alzheimer's. Alzheimer's Research & Therapy. 3: 7. PMID 21418547 DOI: 10.1186/Alzrt66  0.379
2010 Wang H, Song L, Lee A, Laird F, Wong PC, Lee HK. Mossy fiber long-term potentiation deficits in BACE1 knock-outs can be rescued by activation of alpha7 nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13808-13. PMID 20943921 DOI: 10.1523/Jneurosci.1070-10.2010  0.655
2010 Shan X, Chiang PM, Price DL, Wong PC. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 16325-30. PMID 20736350 DOI: 10.1073/pnas.1003459107  0.584
2010 Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 16320-4. PMID 20660762 DOI: 10.1073/Pnas.1002176107  0.675
2010 Chow VW, Savonenko AV, Melnikova T, Kim H, Price DL, Li T, Wong PC. Modeling an anti-amyloid combination therapy for Alzheimer's disease. Science Translational Medicine. 2: 13ra1. PMID 20371462 DOI: 10.1126/Scitranslmed.3000337  0.638
2010 Hoffman PN, Wong PC, Griffin JW, Price DL. Axonal Transport Disorders Encyclopedia of Neuroscience. 1205-1208. DOI: 10.1016/B978-008045046-9.00553-2  0.455
2010 Price DL, Savonenko AV, Albert M, Troncoso JC, Wong PC. Aging of the Brain and Alzheimer's Disease Encyclopedia of Neuroscience. 187-195. DOI: 10.1016/B978-008045046-9.00539-8  0.539
2010 Price DL, Savonenko AV, Li T, Lee MK, Wong PC. Alzheimer Disease: Protein Misfolding, Model Systems, and Experimental Therapeutics Protein Misfolding Diseases: Current and Emerging Principles and Therapies. 231-258. DOI: 10.1002/9780470572702.ch12  0.555
2009 Hayashi I, Takatori S, Urano Y, Iwanari H, Isoo N, Osawa S, Fukuda MA, Kodama T, Hamakubo T, Li T, Wong PC, Tomita T, Iwatsubo T. Single chain variable fragment against nicastrin inhibits the gamma-secretase activity. The Journal of Biological Chemistry. 284: 27838-47. PMID 19684016 DOI: 10.1074/Jbc.M109.055061  0.317
2009 Pardossi-Piquard R, Yang SP, Kanemoto S, Gu Y, Chen F, Böhm C, Sevalle J, Li T, Wong PC, Checler F, Schmitt-Ulms G, St George-Hyslop P, Fraser PE. APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes. The Journal of Biological Chemistry. 284: 16298-307. PMID 19369254 DOI: 10.1074/Jbc.M109.000067  0.304
2008 Wong PC. Translational control of BACE1 may go awry in Alzheimer's disease. Neuron. 60: 941-3. PMID 19109900 DOI: 10.1016/J.Neuron.2008.12.010  0.405
2008 Wang H, Song L, Laird F, Wong PC, Lee HK. BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8677-81. PMID 18753368 DOI: 10.1523/Jneurosci.2440-08.2008  0.653
2008 Savonenko AV, Melnikova T, Laird FM, Stewart KA, Price DL, Wong PC. Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 5585-90. PMID 18385378 DOI: 10.1073/Pnas.0710373105  0.608
2008 Laird FM, Farah MH, Ackerley S, Hoke A, Maragakis N, Rothstein JD, Griffin J, Price DL, Martin LJ, Wong PC. Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1997-2005. PMID 18305234 DOI: 10.1523/Jneurosci.4231-07.2008  0.656
2008 Chandran JS, Lin X, Zapata A, Höke A, Shimoji M, Moore SO, Galloway MP, Laird FM, Wong PC, Price DL, Bailey KR, Crawley JN, Shippenberg T, Cai H. Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function. Neurobiology of Disease. 29: 505-14. PMID 18187333 DOI: 10.1016/J.Nbd.2007.11.011  0.779
2008 Wong PC, Price DL, Bertram L, Tanzi RE. 14 Alzheimer’s Disease: Genetics, Pathogenesis, Models, and Experimental Therapeutics Cold Spring Harbor Monograph Archive. 51: 371-407. DOI: 10.1101/087969824.51.371  0.591
2007 Li T, Wen H, Brayton C, Laird FM, Ma G, Peng S, Placanica L, Wu TC, Crain BJ, Price DL, Eberhart CG, Wong PC. Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10849-59. PMID 17913918 DOI: 10.1523/Jneurosci.2152-07.2007  0.62
2007 Li T, Wen H, Brayton C, Das P, Smithson LA, Fauq A, Fan X, Crain BJ, Price DL, Golde TE, Eberhart CG, Wong PC. Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase. The Journal of Biological Chemistry. 282: 32264-73. PMID 17827153 DOI: 10.1074/Jbc.M703649200  0.523
2007 Choi SH, Leight SN, Lee VM, Li T, Wong PC, Johnson JA, Saraiva MJ, Sisodia SS. Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7006-10. PMID 17596449 DOI: 10.1523/Jneurosci.1919-07.2007  0.384
2007 Laird FM, Farah MH, Lee HK, Savonenko AV, Price DL, Wong PC. β-secretase: Physiological role and target validation Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. 59-76. DOI: 10.1007/978-0-387-35135-3_4  0.469
2006 Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, et al. Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11798-806. PMID 17093100 DOI: 10.1523/Jneurosci.2084-06.2006  0.786
2006 Nishitomi K, Sakaguchi G, Horikoshi Y, Gray AJ, Maeda M, Hirata-Fukae C, Becker AG, Hosono M, Sakaguchi I, Minami SS, Nakajima Y, Li HF, Takeyama C, Kihara T, Ota A, ... Wong PC, et al. BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice. Journal of Neurochemistry. 99: 1555-63. PMID 17083447 DOI: 10.1111/J.1471-4159.2006.04178.X  0.402
2006 Horikoshi Y, Hirata C, Gray AJ, Maeda M, Wong PC, Aisen PS, Kinoshita N, Matsuoka Y. P4-297: Development of full-length mouse amyloid beta ELISA and determination of endogenous Abeta level in BACE1 knockout mice Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.2036  0.355
2005 Wong PC. Alzheimer disease: therapeutic targets for clinical trials. Retina (Philadelphia, Pa.). 25: S80-S81. PMID 16374352 DOI: 10.1097/00006982-200512001-00038  0.309
2005 Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11693-709. PMID 16354928 DOI: 10.1523/Jneurosci.2766-05.2005  0.775
2005 Cai H, Lin X, Xie C, Laird FM, Lai C, Wen H, Chiang HC, Shim H, Farah MH, Hoke A, Price DL, Wong PC. Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7567-74. PMID 16107644 DOI: 10.1523/Jneurosci.1645-05.2005  0.687
2005 Lazarov O, Morfini GA, Lee EB, Farah MH, Szodorai A, DeBoer SR, Koliatsos VE, Kins S, Lee VM, Wong PC, Price DL, Brady ST, Sisodia SS. Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2386-95. PMID 15745965 DOI: 10.1523/Jneurosci.3089-04.2005  0.569
2005 Zhang YW, Luo WJ, Wang H, Lin P, Vetrivel KS, Liao F, Li F, Wong PC, Farquhar MG, Thinakaran G, Xu H. Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. The Journal of Biological Chemistry. 280: 17020-6. PMID 15711015 DOI: 10.1074/Jbc.M409467200  0.337
2005 Ma G, Li T, Price DL, Wong PC. APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 192-8. PMID 15634781 DOI: 10.1523/Jneurosci.3814-04.2005  0.555
2005 Price DL, Borchelt DR, Lee MK, Wong PC. Selected genetically engineered models relevant to human neurodegenerative disease Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 176-195. DOI: 10.1017/CBO9780511544873.016  0.508
2005 Savonenko AV, Laird FM, Troncoso JC, Wong PC, Price DL. Role of Alzheimer's disease models in designing and testing experimental therapeutics Drug Discovery Today: Disease Models. 2: 305-312. DOI: 10.1016/J.Ddmod.2005.11.006  0.619
2005 Price DL, Borchelt DR, Wong PC. Alzheimer's Disease. Clinical Features, Neuropathological and Biochemical Abnormalities, Genetics, Models, and Experimental Therapeutics From Neuroscience to Neurology. 445-458. DOI: 10.1016/B978-012738903-5/50028-X  0.547
2004 Yan XX, Li T, Rominger CM, Prakash SR, Wong PC, Olson RE, Zaczek R, Li YW. Binding sites of gamma-secretase inhibitors in rodent brain: distribution, postnatal development, and effect of deafferentation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2942-52. PMID 15044533 DOI: 10.1523/Jneurosci.0092-04.2004  0.305
2004 Li R, Lindholm K, Yang LB, Yue X, Citron M, Yan R, Beach T, Sue L, Sabbagh M, Cai H, Wong P, Price D, Shen Y. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America. 101: 3632-7. PMID 14978286 DOI: 10.1073/pnas.0205689101  0.671
2004 Ma G, Li T, Price DL, Wong PC. P4-275 APH-1A is required for presenilin-dependent γ-secretase activity during mouse embryogenesis Neurobiology of Aging. 25: S553-S554. DOI: 10.1016/S0197-4580(04)81833-5  0.533
2004 Cai H, Wen H, Laird FM, Chiang H, Xu G, Borchelt DR, Price DL, Wong PC. P1-222 Deletion of BACE1 prevents age-associated neuropathological abnormalities in mutant APP;PS1 mice Neurobiology of Aging. 25: S159. DOI: 10.1016/S0197-4580(04)80535-9  0.678
2004 Laird FM, Savonenko AV, Melnikova T, Cai H, Borchelt DR, Price DL, Wong PC. P1-179 Age-associated memory deficits occurring in Bace1-deficient mice or APP;PS1 mice are restored in APP;PS1 mice lacking BACE1: a role for APP and BACE1 in cognition Neurobiology of Aging. 25: S146. DOI: 10.1016/S0197-4580(04)80492-5  0.679
2004 Li T, Ma G, Peck J, Wen H, Price DL, Wong PC. O3-05-08 Characterization of γ-secretase complex: analysis of APH-1B deficient mice Neurobiology of Aging. 25: S63. DOI: 10.1016/S0197-4580(04)80213-6  0.548
2004 Wong PC, Cai H, Laird FM, Savonenko AV, Melnikova T, Price DL, Borchelt DR, Xu G. S1-01-02 A role for APP and BACE1 in cognition Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80005-8  0.638
2003 Li T, Ma G, Cai H, Price DL, Wong PC. Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3272-7. PMID 12716934  0.67
2003 Martin LJ, Price AC, McClendon KB, Al-Abdulla NA, Subramaniam JR, Wong PC, Liu Z. Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins. Journal of Neurochemistry. 85: 234-47. PMID 12641745 DOI: 10.1046/J.1471-4159.2003.01659.X  0.308
2003 Yang LB, Lindholm K, Yan R, Citron M, Xia W, Yang XL, Beach T, Sue L, Wong P, Price D, Li R, Shen Y. Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease. Nature Medicine. 9: 3-4. PMID 12514700 DOI: 10.1038/nm0103-3  0.555
2003 Li T, Ma G, Cai H, Price DL, Wong PC. Nicastrin Is Required for Assembly of Presenilin/γ-Secretase Complexes to Mediate Notch Signaling and for Processing and Trafficking of β-Amyloid Precursor Protein in Mammals The Journal of Neuroscience. 23: 3272-3277. DOI: 10.1523/Jneurosci.23-08-03272.2003  0.549
2002 Wong PC, Cai H, Borchelt DR, Price DL. Genetically engineered mouse models of neurodegenerative diseases. Nature Neuroscience. 5: 633-9. PMID 12085093 DOI: 10.1038/Nn0702-633  0.723
2002 Subramaniam JR, Lyons WE, Liu J, Bartnikas TB, Rothstein J, Price DL, Cleveland DW, Gitlin JD, Wong PC. Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading. Nature Neuroscience. 5: 301-7. PMID 11889469 DOI: 10.1038/Nn823  0.624
2002 Wong PC. Reply to 'Is ALS caused by an altered oxidative activity of mutant superoxide dismutase?' Nature Neuroscience. 5: 919-920. DOI: 10.1038/Nn1002-919B  0.385
2001 Wong PC, Cai H, Borchelt DR, Price DL. Genetically engineered models relevant to neurodegenerative disorders: their value for understanding disease mechanisms and designing/testing experimental therapeutics. Journal of Molecular Neuroscience : Mn. 17: 233-57. PMID 11816796 DOI: 10.1385/Jmn:17:2:233  0.702
2001 Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiology of Disease. 8: 933-41. PMID 11741389 DOI: 10.1006/nbdi.2001.0443  0.593
2001 Lesuisse C, Xu G, Anderson J, Wong M, Jankowsky J, Holtz G, Gonzalez V, Wong PC, Price DL, Tang F, Wagner S, Borchelt DR. Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice. Human Molecular Genetics. 10: 2525-37. PMID 11709540 DOI: 10.1093/Hmg/10.22.2525  0.603
2001 Wong PC, Price DL, Cai H. The brain's susceptibility to amyloid plaques. Science (New York, N.Y.). 293: 1434. PMID 11526940 DOI: 10.1126/Science.293.5534.1434B  0.69
2001 Cai H, Wang Y, McCarthy D, Wen H, Borchelt DR, Price DL, Wong PC. BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nature Neuroscience. 4: 233-4. PMID 11224536 DOI: 10.1038/85064  0.701
2000 Price DL, Wong PC, Markowska AL, Lee MK, Thinakaren G, Cleveland DW, Sisodia SS, Borchelt DR. The value of transgenic models for the study of neurodegenerative diseases. Annals of the New York Academy of Sciences. 920: 179-91. PMID 11193148 DOI: 10.1111/J.1749-6632.2000.Tb06920.X  0.63
2000 Wong PC, Waggoner D, Subramaniam JR, Tessarollo L, Bartnikas TB, Culotta VC, Price DL, Rothstein J, Gitlin JD. Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 97: 2886-91. PMID 10694572 DOI: 10.1073/Pnas.040461197  0.526
1999 Rothstein JD, Dykes-Hoberg M, Corson LB, Becker M, Cleveland DW, Price DL, Culotta VC, Wong PC. The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. Journal of Neurochemistry. 72: 422-9. PMID 9886096 DOI: 10.1046/j.1471-4159.1999.0720422.x  0.557
1998 Wong PC, Borchelt DR, Lee MK, Pardo CA, Thinakaran G, Martin LJ, Sisodia SS, Price DL. Familial amyotrophic lateral sclerosis and Alzheimer's disease. Transgenic models. Advances in Experimental Medicine and Biology. 446: 145-59. PMID 10079842 DOI: 10.1007/978-1-4615-4869-0_9  0.663
1998 Wong PC, Rothstein JD, Price DL. The genetic and molecular mechanisms of motor neuron disease. Current Opinion in Neurobiology. 8: 791-9. PMID 9914243 DOI: 10.1016/S0959-4388(98)80123-2  0.637
1998 Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, Iwatsubo T, Qian X, Ginty DD, Price DL, Borchelt DR, Wong PC, Sisodia SS. Effects of PS1 deficiency on membrane protein trafficking in neurons. Neuron. 21: 1213-21. PMID 9856475 DOI: 10.1016/S0896-6273(00)80637-6  0.562
1998 Borchelt DR, Wong PC, Sisodia SS, Price DL. Transgenic mouse models of Alzheimer's disease and amyotrophic lateral sclerosis. Brain Pathology (Zurich, Switzerland). 8: 735-57. PMID 9804381 DOI: 10.1111/J.1750-3639.1998.Tb00198.X  0.652
1998 Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiology of Disease. 5: 27-35. PMID 9702785 DOI: 10.1006/Nbdi.1998.0178  0.572
1998 Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9626-30. PMID 9689131 DOI: 10.1073/Pnas.95.16.9626  0.631
1998 Davis JA, Naruse S, Chen H, Eckman C, Younkin S, Price DL, Borchelt DR, Sisodia SS, Wong PC. An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos. Neuron. 20: 603-9. PMID 9539132 DOI: 10.1016/S0896-6273(00)80998-8  0.636
1998 Eyer J, Cleveland DW, Wong PC, Peterson AC. Pathogenesis of two axonopathies does not require axonal neurofilaments. Nature. 391: 584-7. PMID 9468135 DOI: 10.1038/35378  0.356
1997 Price DL, Wong PC, Borchelt DR, Pardo CA, Thinakaran G, Doan AP, Lee MK, Martin LJ, Sisodia SS. Amyotrophic lateral sclerosis and Alzheimer disease. Lessons from model systems. Revue Neurologique. 153: 484-95. PMID 9683997  0.656
1997 Bruijn LI, Beal MF, Becher MW, Schulz JB, Wong PC, Price DL, Cleveland DW. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 94: 7606-11. PMID 9207139 DOI: 10.1073/Pnas.94.14.7606  0.629
1997 Wong PC, Zheng H, Chen H, Becher MW, Sirinathsinghji DJ, Trumbauer ME, Chen HY, Price DL, Van der Ploeg LH, Sisodia SS. Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature. 387: 288-92. PMID 9153393 DOI: 10.1038/387288a0  0.581
1996 Price DL, Becher MW, Wong PC, Borchelt DR, Lee MK, Sisodia SS. Inherited neurodegenerative diseases and transgenic models. Brain Pathology (Zurich, Switzerland). 6: 467-80. PMID 8944317 DOI: 10.1111/J.1750-3639.1996.Tb00876.X  0.628
1996 Lee MK, Borchelt DR, Wong PC, Sisodia SS, Price DL. Transgenic models of neurodegenerative diseases. Current Opinion in Neurobiology. 6: 651-60. PMID 8937830 DOI: 10.1016/S0959-4388(96)80099-7  0.642
1996 Price DL, Koliatsos VE, Wong PC, Pardo CA, Borchelt DR, Lee MK, Cleveland DW, Griffin JW, Hoffman PN, Cork LC, Sisodia SS. Motor neuron disease and model systems: aetiologies, mechanisms and therapies. Ciba Foundation Symposium. 196: 3-13; discussion 13-. PMID 8866125  0.622
1996 Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology. 47: S54-61; discussion S. PMID 8858052 DOI: 10.1212/Wnl.47.4_Suppl_2.54S  0.622
1996 Price D, Borchelt D, Lee M, Wong P, Martin L, Sisodia S. 631 Neurodegenerative Diseases and Model Systems Neurobiology of Aging. 17: S157. DOI: 10.1016/S0197-4580(96)80633-6  0.572
1996 Wong PC, Borchelt DR, Lee MK, Pardo CA, Sisodia SS, Cleveland DW, Koliatsos VE, Price DL. Transgenic and gene-targeting approaches to model disorders of motor neurons Seminars in Neuroscience. 8: 163-169. DOI: 10.1006/Smns.1996.0021  0.645
1995 Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu ZS, Sisodia SS, Price DL, Cleveland DW. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of Biological Chemistry. 270: 3234-8. PMID 7852409 DOI: 10.1074/Jbc.270.7.3234  0.596
1995 Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14: 1105-16. PMID 7605627 DOI: 10.1016/0896-6273(95)90259-7  0.621
1995 Wong PC, Borchelt DR. Motor neuron disease caused by mutations in superoxide dismutase 1. Current Opinion in Neurology. 8: 294-301. PMID 7582045 DOI: 10.1097/00019052-199508000-00008  0.306
1995 Pardo CA, Wong PC, Cleveland DW, Price DL. Gain Of An Adverse Property By A Mutant Sod1 Enzyme Produce Extensive Motor Neuron Abnormalities In Transgenic Mice: 124 Journal of Neuropathology and Experimental Neurology. 54: 442. DOI: 10.1097/00005072-199505000-00140  0.617
1994 Borchelt DR, Lee MK, Slunt HS, Guarnieri M, Xu ZS, Wong PC, Brown RH, Price DL, Sisodia SS, Cleveland DW. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proceedings of the National Academy of Sciences of the United States of America. 91: 8292-6. PMID 8058797 DOI: 10.1073/Pnas.91.17.8292  0.544
Low-probability matches (unlikely to be authored by this person)
2013 Hatzimanolis A, McGrath JA, Wang R, Li T, Wong PC, Nestadt G, Wolyniec PS, Valle D, Pulver AE, Avramopoulos D. Multiple variants aggregate in the neuregulin signaling pathway in a subset of schizophrenia patients. Translational Psychiatry. 3: e264. PMID 23715299 DOI: 10.1038/Tp.2013.33  0.296
2013 LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. Correction: treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice Molecular Neurodegeneration. 8: 26. DOI: 10.1186/1750-1326-8-26  0.295
2015 Shyam R, Ren Y, Lee J, Braunstein KE, Mao HQ, Wong PC. Intraventricular Delivery of siRNA Nanoparticles to the Central Nervous System. Molecular Therapy. Nucleic Acids. 4: e242. PMID 25965552 DOI: 10.1038/Mtna.2015.15  0.292
2010 Hu X, Zhou X, He W, Yang J, Xiong W, Wong P, Wilson CG, Yan R. BACE1 deficiency causes altered neuronal activity and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8819-29. PMID 20592204 DOI: 10.1523/Jneurosci.1334-10.2010  0.288
2008 Chávez-Gutiérrez L, Tolia A, Maes E, Li T, Wong PC, de Strooper B. Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity. The Journal of Biological Chemistry. 283: 20096-105. PMID 18502756 DOI: 10.1074/Jbc.M803040200  0.286
2011 O'Brien RJ, Wong PC. Amyloid precursor protein processing and Alzheimer's disease. Annual Review of Neuroscience. 34: 185-204. PMID 21456963 DOI: 10.1146/annurev-neuro-061010-113613  0.282
1998 Wang P, Chen H, Qin H, Sankarapandi S, Becher MW, Wong PC, Zweier JL. Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury. Proceedings of the National Academy of Sciences of the United States of America. 95: 4556-60. PMID 9539776 DOI: 10.1073/Pnas.95.8.4556  0.28
2012 Hayashi I, Takatori S, Urano Y, Miyake Y, Takagi J, Sakata-Yanagimoto M, Iwanari H, Osawa S, Morohashi Y, Li T, Wong PC, Chiba S, Kodama T, Hamakubo T, Tomita T, et al. Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin. Oncogene. 31: 787-98. PMID 21725355 DOI: 10.1038/Onc.2011.265  0.278
2019 Xu J, Chen L, Wei Z, Chan K, Lu H, Wong PC, Van Zijl P, Li T. P2-367: DEVELOPMENT OF AN IMAGING BIOMARKER, SATURATION TRANSFER MRI, TO MONITOR TAU AGGREGATION IN A TAUOPATHY MOUSE MODEL Alzheimer's & Dementia. 15: P741-P741. DOI: 10.1016/J.Jalz.2019.06.2774  0.274
2019 Müller HP, Brenner D, Roselli F, Wiesner D, Abaei A, Gorges M, Danzer KM, Ludolph AC, Tsao W, Wong PC, Rasche V, Weishaupt JH, Kassubek J. Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the ALS mouse model. Translational Neurodegeneration. 8: 27. PMID 31485326 DOI: 10.1186/S40035-019-0163-Y  0.273
2017 Donde A, Wong PC, Chen LL. Challenges and Advances in Gene Therapy Approaches for Neurodegenerative Disorders. Current Gene Therapy. PMID 29034834 DOI: 10.2174/1566523217666171013124150  0.272
2009 Vassar R, Kovacs DM, Yan R, Wong PC. The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12787-94. PMID 19828790 DOI: 10.1523/Jneurosci.3657-09.2009  0.268
2022 Liang B, Thapa R, Zhang G, Moffitt C, Zhang Y, Zhang L, Johnston A, Ruby HP, Barbera G, Wong PC, Zhang Z, Chen R, Lin DT, Li Y. Aberrant neural activity in prefrontal pyramidal neurons lacking TDP-43 precedes neuron loss. Progress in Neurobiology. 102297. PMID 35667630 DOI: 10.1016/j.pneurobio.2022.102297  0.266
1990 Wong PC, Cleveland DW. Characterization of dominant and recessive assembly-defective mutations in mouse neurofilament NF-M Journal of Cell Biology. 111: 1987-2003. PMID 2121743 DOI: 10.1083/Jcb.111.5.1987  0.263
1995 Wong PC, Marszalek J, Crawford TO, Xu Z, Hsieh ST, Griffin JW, Cleveland DW. Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons. The Journal of Cell Biology. 130: 1413-22. PMID 7559762 DOI: 10.1083/Jcb.130.6.1413  0.263
2010 Oh E, Lyketsos C, Wong P. Mouse Models of Alzheimer's Disease Principles and Practice of Geriatric Psychiatry: Third Edition. 252-256. DOI: 10.1002/9780470669600.ch44  0.263
2012 Makhnevych T, Wong P, Pogoutse O, Vizeacoumar FJ, Greenblatt JF, Emili A, Houry WA. Hsp110 is required for spindle length control. The Journal of Cell Biology. 198: 623-36. PMID 22908312 DOI: 10.1083/Jcb.201111105  0.26
1991 Cleveland DW, Monteiro MJ, Wong PC, Gill SR, Gearhart JD, Hoffman PN. Involvement of neurofilaments in the radial growth of axons Journal of Cell Science. 100: 85-95. PMID 1824110 DOI: 10.1242/Jcs.1991.Supplement_15.12  0.26
2024 Sinha IR, Sandal PS, Burns GD, Mallika AP, Irwin KE, Cruz ALF, Wang V, Rodríguez JL, Wong PC, Ling JP. Large-scale RNA-seq mining reveals ciclopirox triggers TDP-43 cryptic exons. Biorxiv : the Preprint Server For Biology. PMID 38585725 DOI: 10.1101/2024.03.27.587011  0.258
2021 Chen L, van Zijl PCM, Wei Z, Lu H, Duan W, Wong PC, Li T, Xu J. Early detection of Alzheimer's disease using creatine chemical exchange saturation transfer magnetic resonance imaging. Neuroimage. 118071. PMID 33878375 DOI: 10.1016/j.neuroimage.2021.118071  0.257
1990 Gill SR, Wong PC, Monteiro MJ, Cleveland DW. Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit Journal of Cell Biology. 111: 2005-2019. PMID 2121744 DOI: 10.1083/Jcb.111.5.2005  0.256
2011 Zuccaro A, Lahrmann U, Güldener U, Langen G, Pfiffi S, Biedenkopf D, Wong P, Samans B, Grimm C, Basiewicz M, Murat C, Martin F, Kogel K. Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica Plos Pathogens. 7. PMID 22022265 DOI: 10.1371/Journal.Ppat.1002290  0.251
2008 Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. Plos One. 3: e2849. PMID 18682740 DOI: 10.1371/Journal.Pone.0002849  0.25
2008 Cheng H, Vetrivel KS, Drisdel RC, Meckler X, Gong P, Li T, Carter M, Leem J, Chen Y, Nguyen P, Wong PC, Green WN, Kounnas MZ, Thinakaran G. P3-324: Characterization of S-palmitoylation in gamma-secretase subunits Alzheimer's & Dementia. 4: T616-T617. DOI: 10.1016/J.Jalz.2008.05.1893  0.249
2012 Laurie JD, Ali S, Linning R, Mannhaupt G, Wong P, Güldener U, Münsterkötter M, Moore R, Kahmann R, Bakkeren G, Schirawski J. Genome comparison of barley and maize smut fungi reveals targeted loss of RNA silencing components and species-specific presence of transposable elements. The Plant Cell. 24: 1733-45. PMID 22623492 DOI: 10.1105/Tpc.112.097261  0.24
2015 Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport. Nature. 525: 129-33. PMID 26308899 DOI: 10.1038/Nature14974  0.234
2004 Fortna RR, Schaller N, Morais VA, Crystal AS, Li T, Lee VM, Wong PC, Doms RW. P4-319 Assembly, trafficking, and activity of the gamma-secretase complex Neurobiology of Aging. 25: S566. DOI: 10.1016/S0197-4580(04)81877-3  0.234
2009 Cheng H, Vetrivel KS, Drisdel RC, Meckler X, Gong P, Leem JY, Li T, Carter M, Chen Y, Nguyen P, Iwatsubo T, Tomita T, Wong PC, Green WN, Kounnas MZ, et al. S-palmitoylation of gamma-secretase subunits nicastrin and APH-1. The Journal of Biological Chemistry. 284: 1373-84. PMID 19028695 DOI: 10.1074/Jbc.M806380200  0.234
2009 Vetrivel KS, Meckler X, Chen Y, Nguyen PD, Seidah NG, Vassar R, Wong PC, Fukata M, Kounnas MZ, Thinakaran G. Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. The Journal of Biological Chemistry. 284: 3793-803. PMID 19074428 DOI: 10.1074/Jbc.M808920200  0.234
2006 Thibault G, Yudin J, Wong P, Tsitrin V, Sprangers R, Zhao R, Houry WA. Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX. Proceedings of the National Academy of Sciences of the United States of America. 103: 17724-9. PMID 17090685 DOI: 10.1073/Pnas.0601505103  0.231
2011 Wong P, Walter M, Lee W, Mannhaupt G, Münsterkötter M, Mewes HW, Adam G, Güldener U. FGDB: Revisiting the genome annotation of the plant pathogen Fusarium graminearum Nucleic Acids Research. 39. PMID 21051345 DOI: 10.1093/Nar/Gkq1016  0.231
2024 Irwin KE, Jasin P, Braunstein KE, Sinha IR, Garret MA, Bowden KD, Chang K, Troncoso JC, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Miller T, Berry JD, Traynor BJ, ... ... Wong PC, et al. A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD. Nature Medicine. PMID 38278991 DOI: 10.1038/s41591-023-02788-5  0.23
2004 Liu J, Lillo C, Jonsson PA, Vande Velde C, Ward CM, Miller TM, Subramaniam JR, Rothstein JD, Marklund S, Andersen PM, Brännström T, Gredal O, Wong PC, Williams DS, Cleveland DW. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron. 43: 5-17. PMID 15233913 DOI: 10.1016/J.Neuron.2004.06.016  0.229
2004 Morais VA, Fortna RR, Crystal AS, Pijak D, Li T, Wong PC, Costa J, Lee VM, Doms RW. P4-282 Association and localization of nicastrin influences the activity of the G-secretase complex Neurobiology of Aging. 25: S555. DOI: 10.1016/S0197-4580(04)81840-2  0.227
1996 Xu Z, Marszalek JR, Lee MK, Wong PC, Folmer J, Crawford TO, Hsieh ST, Griffin JW, Cleveland DW. Subunit composition of neurofilaments specifies axonal diameter. The Journal of Cell Biology. 133: 1061-9. PMID 8655579 DOI: 10.1083/Jcb.133.5.1061  0.224
2021 Wei Z, Xu J, Chen L, Hirschler L, Barbier EL, Li T, Wong PC, Lu H. Brain metabolism in tau and amyloid mouse models of Alzheimer's disease: An MRI study. Nmr in Biomedicine. e4568. PMID 34050996 DOI: 10.1002/nbm.4568  0.218
2006 Morais VA, Brito C, Pijak DS, Crystal AS, Fortna RR, Li T, Wong PC, Doms RW, Costa J. N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53. Biochimica Et Biophysica Acta. 1762: 802-10. PMID 16938437 DOI: 10.1016/J.Bbadis.2006.06.018  0.217
2010 Schirawski J, Mannhaupt G, Münch K, Brefort T, Schipper K, Doehlemann G, Di Stasio M, Rössel N, Mendoza-Mendoza A, Pester D, Müller O, Winterberg B, Meyer E, Ghareeb H, Wollenberg T, ... ... Wong P, et al. Pathogenicity determinants in smut fungi revealed by genome comparison. Science (New York, N.Y.). 330: 1546-8. PMID 21148393 DOI: 10.1126/Science.1195330  0.217
2022 Gonzalez-Gil A, Porell RN, Fernandes SM, Maenpaa E, August Li T, Li T, Wong PC, Aoki K, Tiemeyer M, Yu ZJ, Orsburn BC, Bumpus NN, Matthews RT, Schnaar RL. Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease. The Journal of Biological Chemistry. 101960. PMID 35452678 DOI: 10.1016/j.jbc.2022.101960  0.214
2008 Vetrivel KS, Meckler X, Chen Y, Nguyen PD, Li T, Wong PC, Seidah NG, Vassar R, Thinakaran G. O2-03-01: Exploring β-secretase activity in lipid raft microdomains Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.322  0.212
2013 Laurie JD, Linning R, Wong P, Bakkeren G. Do TE activity and counteracting genome defenses, RNAi and methylation, shape the sex lives of smut fungi? Plant Signaling & Behavior. 8: e23853. PMID 23425853 DOI: 10.4161/Psb.23853  0.211
2006 Hu X, Hicks CW, He W, Wong P, Macklin WB, Trapp BD, Yan R. Bace1 modulates myelination in the central and peripheral nervous system. Nature Neuroscience. 9: 1520-5. PMID 17099708 DOI: 10.1038/Nn1797  0.208
2010 Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/Pnas.0909284107  0.208
2004 Carroll MC, Girouard JB, Ulloa JL, Subramaniam JR, Wong PC, Valentine JS, Culotta VL. Erratum: Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone (Proceedings of the National Academy of Sciences of the United States of America (April 20, 2004) 101, 16 (5964-5969)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0402658101  0.205
2000 Sampei K, Mandir AS, Asano Y, Wong PC, Traystman RJ, Dawson VL, Dawson TM, Hurn PD. Stroke outcome in double-mutant antioxidant transgenic mice. Stroke; a Journal of Cerebral Circulation. 31: 2685-91. PMID 11062295 DOI: 10.1161/01.Str.31.11.2685  0.203
2023 Sattler R, Traynor BJ, Robertson J, Van Den Bosch L, Barmada SJ, Svendsen CN, Disney MD, Gendron TF, Wong PC, Turner MR, Boxer A, Babu S, Benatar M, Kurnellas M, Rohrer JD, et al. Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit. Neurology and Therapy. PMID 37847372 DOI: 10.1007/s40120-023-00548-8  0.201
2021 Campbell KM, Xu Y, Patel C, Rayl JM, Zomer HD, Osuru HP, Pratt M, Pramoonjago P, Timken M, Miller LM, Ralph A, Storey KM, Peng Y, Drnevich J, Lagier-Tourenne C, ... Wong PC, et al. Loss of TDP-43 in male germ cells causes meiotic failure and impairs fertility in mice. The Journal of Biological Chemistry. 101231. PMID 34599968 DOI: 10.1016/j.jbc.2021.101231  0.2
2004 Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. The Journal of Biological Chemistry. 279: 44945-54. PMID 15322084 DOI: 10.1074/Jbc.M407986200  0.187
2005 Wong P. [AM-10]: BACE Alzheimer's & Dementia. 1: S3-S3. DOI: 10.1016/j.jalz.2005.06.037  0.184
2010 Chow VW, Mattson MP, Wong PC, Gleichmann M. An overview of APP processing enzymes and products. Neuromolecular Medicine. 12: 1-12. PMID 20232515 DOI: 10.1007/S12017-009-8104-Z  0.184
2023 Liu G, Wang J, Wei Z, Fang CL, Shen K, Qian C, Qi C, Li T, Gao P, Wong PC, Lu H, Cao X, Wan M. Elevated PDGF-BB from Bone Impairs Hippocampal Vasculature by Inducing PDGFRβ Shedding from Pericytes. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2206938. PMID 37102631 DOI: 10.1002/advs.202206938  0.178
1999 Ratovitski T, Corson LB, Strain J, Wong P, Cleveland DW, Culotta VC, Borchelt DR. Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds. Human Molecular Genetics. 8: 1451-60. PMID 10400992 DOI: 10.1093/Hmg/8.8.1451  0.175
2005 Wong P, Fritz A, Frishman D. Designability, aggregation propensity and duplication of disease-associated proteins. Protein Engineering, Design & Selection : Peds. 18: 503-8. PMID 16155116 DOI: 10.1093/protein/gzi056  0.169
2024 Irwin KE, Sheth U, Wong PC, Gendron TF. Fluid biomarkers for amyotrophic lateral sclerosis: a review. Molecular Neurodegeneration. 19: 9. PMID 38267984 DOI: 10.1186/s13024-023-00685-6  0.16
2014 Schumacher WA, Wang X, Wong PC. New advances in treating thrombotic diseases. Drug Discovery Today. 19: 1433-4. PMID 24959954 DOI: 10.1016/j.drudis.2014.06.015  0.144
2013 Ma D, Wei H, Lu J, Ho S, Zhang G, Sun X, Oh Y, Tan SH, Ng ML, Shim W, Wong P, Liew R. Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy. European Heart Journal. 34: 1122-33. PMID 22798562 DOI: 10.1093/Eurheartj/Ehs226  0.143
2017 Mehta A, Ramachandra CJA, Singh P, Chitre A, Lua CH, Mura M, Crotti L, Wong P, Schwartz PJ, Gnecchi M, Shim W. Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model. European Heart Journal. PMID 29020304 DOI: 10.1093/Eurheartj/Ehx394  0.142
2013 Wong PC, Fung AT, Gerrie AS, Moloney G, Maberley D, Rossman D, White V, Collins D, Coupland R, Chen LY. IgG4-related disease with hypergammaglobulinemic hyperviscosity and retinopathy. European Journal of Haematology. 90: 250-6. PMID 23278107 DOI: 10.1111/ejh.12059  0.14
2004 Carroll MC, Girouard JB, Ulloa JL, Subramaniam JR, Wong PC, Valentine JS, Culotta VC. Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone. Proceedings of the National Academy of Sciences of the United States of America. 101: 5964-9. PMID 15069187 DOI: 10.1073/Pnas.0308298101  0.14
2006 Wong P, Frishman D. Fold designability, distribution, and disease. Plos Computational Biology. 2: e40. PMID 16680196 DOI: 10.1371/journal.pcbi.0020040  0.137
2009 Chow WN, Lee YL, Wong PC, Chung MK, Lee KF, Yeung WS. Complement 3 deficiency impairs early pregnancy in mice. Molecular Reproduction and Development. 76: 647-55. PMID 19205046 DOI: 10.1002/mrd.21013  0.136
2011 Wong PC, Pinto DJ, Zhang D. Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor. Journal of Thrombosis and Thrombolysis. 31: 478-92. PMID 21318583 DOI: 10.1007/s11239-011-0551-3  0.133
2009 Wong P, Frishman D. Designability and disease. Methods in Molecular Biology (Clifton, N.J.). 484: 491-504. PMID 18592197 DOI: 10.1007/978-1-59745-398-1_29  0.131
2015 Ramachandra CJ, Mehta A, Wong P, Shim W. ErbB4 Activated p38γ MAPK Isoform Mediates Early Cardiogenesis Through NKx2.5 in Human Pluripotent Stem Cells. Stem Cells (Dayton, Ohio). PMID 26418945 DOI: 10.1002/stem.2223  0.13
2012 Wong PC, Leung YY, Li EK, Tam LS. Measuring disease activity in psoriatic arthritis. International Journal of Rheumatology. 2012: 839425. PMID 23319952 DOI: 10.1155/2012/839425  0.129
1997 Wang P, Wong PC, Sankarapandi S, Qin H, Chacko VP, Zweier JL. Overexpression of wild-type human SOD1 in mice prevents myocardial reperfusion injury Faseb Journal. 11: A272.  0.129
1999 Berechid BE, Thinakaran G, Wong PC, Sisodia SS, Nye JS. Lack of requirement for presenilin1 in Notch1 signaling. Current Biology : Cb. 9: 1493-6. PMID 10607593 DOI: 10.1016/S0960-9822(00)80121-9  0.126
2012 Kwok JS, Wong PC, Luk MC, Chan MH. Use of glycosylated ferritin assay to aid the diagnosis of adult-onset Still's disease: a local laboratory experience in Hong Kong. Rheumatology International. 32: 2583-4. PMID 21785960 DOI: 10.1007/s00296-011-2006-8  0.124
2008 Mattar CN, Harharah L, Su LL, Agarwal AA, Wong PC, Choolani M. Menopause, hormone therapy and cardiovascular and cerebrovascular disease. Annals of the Academy of Medicine, Singapore. 37: 54-62. PMID 18265899  0.123
2013 Fam HK, Walton C, Mitra SA, Chowdhury M, Osborne N, Choi K, Sun G, Wong PC, O'Sullivan MJ, Turashvili G, Aparicio S, Triche TJ, Bond M, Pallen CJ, Boerkoel CF. TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells. Molecular Cancer Research : McR. 11: 1179-92. PMID 23913164 DOI: 10.1158/1541-7786.Mcr-12-0575  0.122
2015 Chen LY, Wong PC, Noda S, Collins DR, Sreenivasan GM, Coupland RC. Polyclonal hyperviscosity syndrome in IgG4-related disease and associated conditions. Clinical Case Reports. 3: 217-26. PMID 25914812 DOI: 10.1002/ccr3.201  0.122
2015 Ramachandra CJ, Mehta A, Guo KW, Wong P, Tan JL, Shim W. Molecular pathogenesis of Marfan syndrome. International Journal of Cardiology. 187: 585-591. PMID 25863307 DOI: 10.1016/j.ijcard.2015.03.423  0.122
2022 Wong P, Baidya S, Daly J, Powley T. Haemoglobin S testing using HEA BeadChip™ technology: Lifeblood comparison with clinical diagnosis. Vox Sanguinis. PMID 35522596 DOI: 10.1111/vox.13289  0.121
2024 Irwin KE, Jasin P, Braunstein KE, Sinha IR, Garret MA, Bowden KD, Chang K, Troncoso JC, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Miller T, Berry JD, Traynor BJ, ... ... Wong PC, et al. Author Correction: A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD. Nature Medicine. PMID 38580817 DOI: 10.1038/s41591-024-02966-z  0.12
2016 Li X, Stanislaus S, Asuncion F, Niu QT, Chinookoswong N, Villasenor K, Wang J, Wong P, Boyce R, Dwyer D, Han CY, Chen MM, Liu B, Stolina M, Ke HZ, et al. FGF21 Is not a Major Mediator for Bone Homeostasis or Metabolic Actions of PPARα and PPARγ Agonists. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27505721 DOI: 10.1002/Jbmr.2936  0.114
2008 Chan-Yeung M, Lai CK, Chan KS, Cheung AH, Yao TJ, Ho AS, Ko FW, Yam LY, Wong PC, Tsang KW, Lam WK, Ho JC, Chu CM, Yu WC, Chan HS, et al. The burden of lung disease in Hong Kong: a report from the Hong Kong Thoracic Society. Respirology (Carlton, Vic.). 13: S133-65. PMID 18945323 DOI: 10.1111/j.1440-1843.2008.01394.x  0.114
2012 Wong PC, Chandrasekaran B, Zheng J. The derived allele of ASPM is associated with lexical tone perception. Plos One. 7: e34243. PMID 22529908 DOI: 10.1371/Journal.Pone.0034243  0.111
2010 Perera SC, Wong P, Krell PJ, Arif BM. Expression of heterologous genes in the Amsacta moorei entomopoxvirus. Journal of Virological Methods. 165: 1-8. PMID 19477199 DOI: 10.1016/j.jviromet.2009.05.015  0.109
2007 Chan-Yeung M, Ho SP, Cheung AH, So LK, Wong PC, Chan KK, Chan JW, Ip MS, Mak JC. Polymorphisms of glutathione S-transferase genes and functional activity in smokers with or without COPD. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 11: 508-14. PMID 17439673  0.109
2004 Wong P, Houry WA. Chaperone networks in bacteria: analysis of protein homeostasis in minimal cells. Journal of Structural Biology. 146: 79-89. PMID 15037239 DOI: 10.1016/j.jsb.2003.11.006  0.108
2009 Winter SL, Wong P, Alexandrow MG. In vivo chromatin decondensation assays: molecular genetic analysis of chromatin unfolding characteristics of selected proteins. Methods in Molecular Biology (Clifton, N.J.). 523: 27-40. PMID 19381923 DOI: 10.1007/978-1-59745-190-1_3  0.107
2015 Chen M, Loh SF, Yu SL, Nair S, Tan HH, Nadarajah S, Wong PC, Ng SC, Prasath EB, Tan AS, Cheah FS, Saw EE, Chong SS. Rapid and reliable preimplantation genetic diagnosis of common Hb Bart's hydrops fetalis syndrome and Hb H disease determinants using an enhanced single-tube decaplex PCR assay. American Journal of Hematology. PMID 26043722 DOI: 10.1002/ajh.24077  0.107
2007 Bessette DC, Wong PC, Pallen CJ. PRL-3: a metastasis-associated phosphatase in search of a function. Cells, Tissues, Organs. 185: 232-6. PMID 17587829 DOI: 10.1159/000101324  0.107
2003 Wong WM, Ho JC, Ooi GC, Mok T, Chan J, Hung IF, Ng W, Lam YM, Tam WO, Wong BC, Wong PC, Ho PL, Lai CL, Lam WK, Lam SK, et al. Temporal patterns of hepatic dysfunction and disease severity in patients with SARS. Jama. 290: 2663-5. PMID 14645306 DOI: 10.1001/jama.290.20.2663  0.105
2013 Antoniou M, Gunasekera GM, Wong PC. Foreign language training as cognitive therapy for age-related cognitive decline: a hypothesis for future research. Neuroscience and Biobehavioral Reviews. 37: 2689-98. PMID 24051310 DOI: 10.1016/J.Neubiorev.2013.09.004  0.104
2015 Lee R, Foin N, Otsuka F, Wong P, Mari JM, Joner M, Girard MJ, Virmani R. Intravascular Assessment of Arterial Disease Using Compensated OCT in Comparison With Histology. Jacc. Cardiovascular Imaging. PMID 25797128 DOI: 10.1016/j.jcmg.2015.01.012  0.104
2015 Li PH, Chau CH, Wong PC. Melioidosis mycotic aneurysm: An uncommon complication of an uncommon disease. Respiratory Medicine Case Reports. 14: 43-6. PMID 26029577 DOI: 10.1016/j.rmcr.2014.12.005  0.103
2000 Han Q, Dominguez C, Stouten PF, Park JM, Duffy DE, Galemmo RA, Rossi KA, Alexander RS, Smallwood AM, Wong PC, Wright MM, Luettgen JM, Knabb RM, Wexler RR. Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors. Journal of Medicinal Chemistry. 43: 4398-415. PMID 11087565 DOI: 10.1021/jm000113t  0.103
2015 Friedman DM, Domachowske JB, Wong PC, Parimi PS, Garcia DF, Marcus MG, La Via WV, Syed IA, Szabo SM, McLaurin KK, Kumar VR. Perceived Risk of Severe Respiratory Syncytial Virus Disease and Immunoprophylaxis Use Among US Pediatric Specialists. Clinical Pediatrics. PMID 26400767 DOI: 10.1177/0009922815604598  0.102
2014 Wong P, Houghton P, Kirsch DG, Finkelstein SE, Monjazeb AM, Xu-Welliver M, Dicker AP, Ahmed M, Vikram B, Teicher BA, Coleman CN, Machtay M, Curran WJ, Wang D. Combining targeted agents with modern radiotherapy in soft tissue sarcomas. Journal of the National Cancer Institute. 106. PMID 25326640 DOI: 10.1093/Jnci/Dju329  0.101
2013 Ma D, Wei H, Zhao Y, Lu J, Li G, Sahib NB, Tan TH, Wong KY, Shim W, Wong P, Cook SA, Liew R. Modeling type 3 long QT syndrome with cardiomyocytes derived from patient-specific induced pluripotent stem cells. International Journal of Cardiology. 168: 5277-86. PMID 23998552 DOI: 10.1016/J.Ijcard.2013.08.015  0.1
2010 Wang W, Yap CH, Loh SF, Tan AS, Lim MN, Prasath EB, Chan ML, Tan WC, Jiang B, Yeo GH, Mathew J, Ho A, Ho SS, Wong PC, Choolani MA, et al. Simplified PGD of common determinants of haemoglobin Bart's hydrops fetalis syndrome using multiplex-microsatellite PCR. Reproductive Biomedicine Online. 21: 642-8. PMID 20864413 DOI: 10.1016/j.rbmo.2010.06.021  0.1
2010 Wong PC, Luettgen JM, Rendina AR, Kettner CA, Xin B, Knabb RM, Wexler R, Priestley ES. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thrombosis and Haemostasis. 104: 261-9. PMID 20589312 DOI: 10.1160/TH10-01-0025  0.099
2022 Lyudovyk O, Kim JY, Qualls D, Hwee MA, Lin YH, Boutemine SR, Elhanati Y, Solovyov A, Douglas M, Chen E, Babady NE, Ramanathan L, Vedantam P, Bandlamudi C, Gouma S, ... Wong P, et al. Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses. Cancer Cell. PMID 35679859 DOI: 10.1016/j.ccell.2022.05.013  0.099
2009 Antonov AV, Dietmann S, Wong P, Igor R, Mewes HW. PLIPS, an automatically collected database of protein lists reported by proteomics studies Journal of Proteome Research. 8: 1193-1197. PMID 19216535 DOI: 10.1021/pr800804d  0.094
2008 Wong PC. Adding a visualization feature to web search engines: it's time. Ieee Computer Graphics and Applications. 28: 11-3. PMID 19004680 DOI: 10.1109/MCG.2008.110  0.092
2018 Nguyen HH, Swain MG, Wong P, Congly SE. Canadian regulations and legal ramifications for hepatic encephalopathy: a descriptive analysis. Cmaj Open. 6: E575-E579. PMID 30510040 DOI: 10.9778/cmajo.20180024  0.091
2021 Lafontaine J, Cardin GB, Malaquin N, Boisvert JS, Rodier F, Wong P. Senolytic Targeting of Bcl-2 Anti-Apoptotic Family Increases Cell Death in Irradiated Sarcoma Cells. Cancers. 13. PMID 33494434 DOI: 10.3390/cancers13030386  0.09
1999 Quan ML, Ellis CD, Liauw AY, Alexander RS, Knabb RM, Lam G, Wright MR, Wong PC, Wexler RR. Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2. Journal of Medicinal Chemistry. 42: 2760-73. PMID 10425087 DOI: 10.1021/jm980406a  0.089
2015 How C, Pintilie M, Bruce JP, Hui AB, Clarke BA, Wong P, Yin S, Yan R, Waggott D, Boutros PC, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF. Developing a prognostic micro-RNA signature for human cervical carcinoma. Plos One. 10: e0123946. PMID 25880806 DOI: 10.1371/Journal.Pone.0123946  0.087
2021 Jutras G, Wong P, Ferreira J, Leblanc JF. IgG4-associated autoimmune hepatitis and cholangitis: A relatively novel entity to consider in cases of seronegative autoimmune hepatitis. Canadian Liver Journal. 4: 99-103. PMID 35991763 DOI: 10.3138/canlivj-2020-0023  0.086
1999 Quan ML, Liauw AY, Ellis CD, Pruitt JR, Carini DJ, Bostrom LL, Huang PP, Harrison K, Knabb RM, Thoolen MJ, Wong PC, Wexler RR. Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1. Journal of Medicinal Chemistry. 42: 2752-9. PMID 10425086 DOI: 10.1021/jm980405i  0.086
2016 Chan CH, Wong P. Molecular Predictors of Radiotherapy Response in Sarcoma. Current Treatment Options in Oncology. 17: 2. PMID 26714494 DOI: 10.1007/s11864-015-0381-1  0.085
2020 Shengir M, Krishnamurthy S, Ghali P, Deschenes M, Wong P, Chen T, Sebastiani G. Prevalence and predictors of nonalcoholic fatty liver disease in South Asian women with polycystic ovary syndrome. World Journal of Gastroenterology. 26: 7046-7060. PMID 33311949 DOI: 10.3748/wjg.v26.i44.7046  0.085
2021 Hu E, Hong FT, Aral J, Long J, Piper DE, Poppe L, Andrews KL, Hager T, Davis C, Li H, Wong P, Gavva N, Shi L, Zhu DXD, Lehto SG, et al. Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model. Journal of Medicinal Chemistry. PMID 33715378 DOI: 10.1021/acs.jmedchem.0c01396  0.083
2001 Pinto DJ, Orwat MJ, Wang S, Fevig JM, Quan ML, Amparo E, Cacciola J, Rossi KA, Alexander RS, Smallwood AM, Luettgen JM, Liang L, Aungst BJ, Wright MR, Knabb RM, ... Wong PC, et al. Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. Journal of Medicinal Chemistry. 44: 566-78. PMID 11170646 DOI: 10.1021/jm000409z  0.083
2008 Wong PC, Crain EJ, Xin B, Wexler RR, Lam PY, Pinto DJ, Luettgen JM, Knabb RM. Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies. Journal of Thrombosis and Haemostasis : Jth. 6: 820-9. PMID 18315548 DOI: 10.1111/j.1538-7836.2008.02939.x  0.083
2022 Bahig H, Tonneau M, Blais N, Wong P, Filion E, Campeau MP, Vu T, Al-Saleh A, Tehfé M, Florescu M, Roberge D, Masucci L, Richard C, Menard C, Routy B. tereotactic Ablative Radiotherapy for oligo-progressive disease refractory to systemic therapy in Non-Small Cell Lung Cancer: A registry-based phase II randomized trial (SUPPRESS-NSCLC). Clinical and Translational Radiation Oncology. 33: 115-119. PMID 35243022 DOI: 10.1016/j.ctro.2021.12.008  0.082
2011 Wong PC, Crain EJ, Watson CA, Schumacher WA. A small-molecule factor XIa inhibitor produces antithrombotic efficacy with minimal bleeding time prolongation in rabbits. Journal of Thrombosis and Thrombolysis. 32: 129-37. PMID 21614454 DOI: 10.1007/s11239-011-0599-0  0.082
2010 Wong PC, Jiang X. Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin. Thrombosis and Haemostasis. 104: 302-10. PMID 20589316 DOI: 10.1160/TH10-02-0097  0.081
2010 Moe KT, Wong P. Current trends in diagnostic biomarkers of acute coronary syndrome. Annals of the Academy of Medicine, Singapore. 39: 210-5. PMID 20372757  0.08
2017 Gandier JA, Langelaan DN, Won A, O'Donnell K, Grondin JL, Spencer HL, Wong P, Tillier E, Yip C, Smith SP, Master ER. Characterization of a Basidiomycota hydrophobin reveals the structural basis for a high-similarity Class I subdivision. Scientific Reports. 7: 45863. PMID 28393921 DOI: 10.1038/Srep45863  0.079
2014 Leung YY, Ho KW, Li EK, Li M, Kwok LW, Wong PC, Li TK, Zhu TY, Kun EW, Tam LS. Predictors of functional deterioration in Chinese patients with psoriatic arthritis: a longitudinal study. Bmc Musculoskeletal Disorders. 15: 284. PMID 25160684 DOI: 10.1186/1471-2474-15-284  0.078
2021 Ramachandra CJA, Kp MMJ, Chua J, Hernandez-Resendiz S, Liehn EA, Gan LM, Michaëlsson E, Jonsson MKB, Ryden-Markinhuhta K, Bhat RV, Fritsche-Danielson R, Lin YH, Sadayappan S, Tang HC, Wong P, et al. Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes. Cardiovascular Research. PMID 33705529 DOI: 10.1093/cvr/cvab077  0.077
2014 Vilstrup H, Amodio P, Bajaj J, Cordoba J, Ferenci P, Mullen KD, Weissenborn K, Wong P. Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology (Baltimore, Md.). 60: 715-35. PMID 25042402 DOI: 10.1002/Hep.27210  0.076
2007 Wong PC, Crain EJ, Watson CA, Jiang X, Hua J, Bostwick JS, Ogletree ML, Schumacher WA, Rehfuss R. Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits. Journal of Cardiovascular Pharmacology. 49: 316-24. PMID 17513951 DOI: 10.1097/FJC.0b013e31803e8772  0.076
2009 Margulis EH, Mlsna LM, Uppunda AK, Parrish TB, Wong PC. Selective neurophysiologic responses to music in instrumentalists with different listening biographies. Human Brain Mapping. 30: 267-75. PMID 18072277 DOI: 10.1002/Hbm.20503  0.076
2010 Ng SY, Reboud J, Wang KY, Tang KC, Zhang L, Wong P, Moe KT, Shim W, Chen Y. Label-free impedance detection of low levels of circulating endothelial progenitor cells for point-of-care diagnosis. Biosensors & Bioelectronics. 25: 1095-101. PMID 19926471 DOI: 10.1016/j.bios.2009.09.031  0.075
2012 Soh BS, Zheng D, Li Yeo JS, Yang HH, Ng SY, Wong LH, Zhang W, Li P, Nichane M, Asmat A, Wong PS, Wong PC, Su LL, Mantalaris SA, Lu J, et al. CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2335-46. PMID 22968480 DOI: 10.1038/Mt.2012.182  0.074
2022 Kablawi D, Alhinai A, Wong P, Deschenes M, Sebastiani G, Benmassaoud A. Splenomegaly is a marker of advanced chronic liver disease and portal hypertension in HIV infection. Hiv Medicine. PMID 36042533 DOI: 10.1111/hiv.13390  0.074
1993 Lee MK, Xu Z, Wong PC, Cleveland DW. Neurofilaments are obligate heteropolymers in vivo. The Journal of Cell Biology. 122: 1337-50. PMID 8376466 DOI: 10.1083/Jcb.122.6.1337  0.074
2015 Wong PC, Quan ML, Watson CA, Crain EJ, Harpel MR, Rendina AR, Luettgen JM, Wexler RR, Schumacher WA, Seiffert DA. In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa. Journal of Thrombosis and Thrombolysis. PMID 26249722 DOI: 10.1007/s11239-015-1258-7  0.074
2023 Yan M, Abdel-Rahman F, Dawson L, Wong P, Wong RKS, Tsai CJ. Advances and Challenges in Trials of Local Therapy for Patients With Oligometastatic or Oligoprogressive Disease. Seminars in Radiation Oncology. 33: 416-428. PMID 37684071 DOI: 10.1016/j.semradonc.2023.07.001  0.073
2017 Wong PC, Guo J, Zhang A. The renal and cardiovascular effects of natriuretic peptides. Advances in Physiology Education. 41: 179-185. PMID 28377431 DOI: 10.1152/advan.00177.2016  0.073
2013 Walsh C, Barkun J, Tchervenkov J, Deschenes M, Ghali P, Wong P, Chaudhury P, Paraskevas S, Metrakos P, Cantarovich M. Anti-CD25 monoclonal antibody replacement therapy for chronic kidney disease in liver transplant recipients. Transplantation. 95: 495-500. PMID 23296149 DOI: 10.1097/Tp.0B013E318277230E  0.073
2014 Sheng J, Shim W, Lu J, Lim SY, Ong BH, Lim TS, Liew R, Chua YL, Wong P. Electrophysiology of human cardiac atrial and ventricular telocytes. Journal of Cellular and Molecular Medicine. 18: 355-62. PMID 24467431 DOI: 10.1111/Jcmm.12240  0.073
2014 Al-Busafi SA, Ghali P, Deschênes M, Wong P. Chylous Ascites: Evaluation and Management. Isrn Hepatology. 2014: 240473. PMID 27335837 DOI: 10.1155/2014/240473  0.073
2021 Refet-Mollof E, Najyb O, Chermat R, Glory A, Lafontaine J, Wong P, Gervais T. Hypoxic Jumbo Spheroids On-A-Chip (HOnAChip): Insights into Treatment Efficacy. Cancers. 13. PMID 34439199 DOI: 10.3390/cancers13164046  0.072
2019 Roy SF, Louie AV, Liberman M, Wong P, Bahig H. Pathologic response after modern radiotherapy for non-small cell lung cancer. Translational Lung Cancer Research. 8: S124-S134. PMID 31673516 DOI: 10.21037/Tlcr.2019.09.05  0.072
2020 Krahn T, Martel M, Sapir-Pichhadze R, Kronfli N, J F, G G, B L, Klein MB, Wong P, Deschenes M, Ghali P, Sebastiani G. Non-alcoholic fatty liver disease predicts development of metabolic comorbidities in HIV-infected patients. The Journal of Infectious Diseases. PMID 32249283 DOI: 10.1093/Infdis/Jiaa170  0.071
2015 Lin JS, Zhou L, Sagayaraj A, Jumat NH, Choolani M, Chan JK, Biswas A, Wong PC, Lim SG, Dan YY. Hepatic differentiation of Human Amniotic Epithelial cells and in vivo therapeutic effect on animal model of cirrhosis. Journal of Gastroenterology and Hepatology. PMID 25973537 DOI: 10.1111/jgh.12991  0.071
2011 Chiang PM, Wong PC. Differentiation of an embryonic stem cell to hemogenic endothelium by defined factors: essential role of bone morphogenetic protein 4. Development (Cambridge, England). 138: 2833-43. PMID 21613326 DOI: 10.1242/dev.061440  0.071
2015 Bhat M, Ghali P, Rollet-Kurhajec KC, Bhat A, Wong P, Deschenes M, Sebastiani G. Serum fibrosis biomarkers predict death and graft loss in liver transplant recipients. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 26194602 DOI: 10.1002/lt.24217  0.07
2012 Wong PC, Li Z, Guo J, Zhang A. Pathophysiology of contrast-induced nephropathy. International Journal of Cardiology. 158: 186-92. PMID 21784541 DOI: 10.1016/j.ijcard.2011.06.115  0.07
2022 Murali A, Wong P, Gilbar PJ, Mangos HM. Acquired Hemophilia A following Pfizer-BioNTech SARS CoV-2 mRNA vaccine, successfully treated with prednisolone and rituximab. Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners. 10781552221075545. PMID 35088622 DOI: 10.1177/10781552221075545  0.07
2011 Sheppard JP, Wang JP, Wong PC. Large-scale cortical functional organization and speech perception across the lifespan. Plos One. 6: e16510. PMID 21304991 DOI: 10.1371/Journal.Pone.0016510  0.069
2004 Koulouri S, Acherman RJ, Wong PC, Chan LS, Lewis AB. Utility of B-type natriuretic peptide in differentiating congestive heart failure from lung disease in pediatric patients with respiratory distress. Pediatric Cardiology. 25: 341-6. PMID 15054559 DOI: 10.1007/s00246-003-0578-0  0.069
2004 Shim WS, Jiang S, Wong P, Tan J, Chua YL, Tan YS, Sin YK, Lim CH, Chua T, Teh M, Liu TC, Sim E. Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells. Biochemical and Biophysical Research Communications. 324: 481-8. PMID 15474453 DOI: 10.1016/j.bbrc.2004.09.087  0.069
2009 Antonov AV, Dietmann S, Wong P, Mewes HW. TICL - A web tool for network-based interpretation of compound lists inferred by high-throughput metabolomics Febs Journal. 276: 2084-2094. PMID 19292876 DOI: 10.1111/j.1742-4658.2009.06943.x  0.068
2004 Kwok JS, Lawton JW, Yew WW, Chau CH, Lee J, Wong PC. Protease inhibitor phenotypes and serum alpha-1-antitrypsin levels in patients with COPD: a study from Hong Kong. Respirology (Carlton, Vic.). 9: 265-70. PMID 15182280 DOI: 10.1111/j.1440-1843.2004.00560.x  0.068
2010 Shim W, Mehta A, Lim SY, Zhang G, Lim CH, Chua T, Wong P. G-CSF for stem cell therapy in acute myocardial infarction: friend or foe? Cardiovascular Research. 89: 20-30. PMID 20851808 DOI: 10.1093/cvr/cvq301  0.067
2004 Jones BM, Ma ES, Peiris JS, Wong PC, Ho JC, Lam B, Lai KN, Tsang KW. Prolonged disturbances of in vitro cytokine production in patients with severe acute respiratory syndrome (SARS) treated with ribavirin and steroids. Clinical and Experimental Immunology. 135: 467-73. PMID 15008980 DOI: 10.1111/j.1365-2249.2003.02391.x  0.067
2022 Lazarides AL, Burke ZDC, Gundavda MK, Novak R, Ghert M, Wilson DA, Rose PS, Wong P, Griffin AM, Ferguson PC, Wunder JS, Houdek MT, Tsoi KM. How Do the Outcomes of Radiation-Associated Pelvic and Sacral Bone Sarcomas Compare to Primary Osteosarcomas following Surgical Resection? Cancers. 14. PMID 35565308 DOI: 10.3390/cancers14092179  0.067
2005 Wong P, Lee C, Tannock IF. Reduction of intracellular pH as a strategy to enhance the pH-dependent cytotoxic effects of melphalan for human breast cancer cells Clinical Cancer Research. 11: 3553-3557. PMID 15867259 DOI: 10.1158/1078-0432.Ccr-04-2472  0.067
2003 Wang X, Xu L, Wang H, Grzanna R, Zhan Y, Knabb RM, Luettgen JM, Bozarth TA, Galemmo RA, Wong PC, Bernard R, Vargas H, Chopp M, Friedman SM, Feuerstein GZ. Inhibition of factor Xa reduces ischemic brain damage after thromboembolic stroke in rats. Stroke; a Journal of Cerebral Circulation. 34: 468-74. PMID 12574562 DOI: 10.1161/01.STR.0000049765.81774.A3  0.067
2007 Schumacher WA, Bostwick JS, Ogletree ML, Stewart AB, Steinbacher TE, Hua J, Price LA, Wong PC, Rehfuss RP. Biomarker optimization to track the antithrombotic and hemostatic effects of clopidogrel in rats. The Journal of Pharmacology and Experimental Therapeutics. 322: 369-77. PMID 17420297 DOI: 10.1124/jpet.106.119156  0.066
2021 Shengir M, Chen T, Guadagno E, Ramanakumar AV, Ghali P, Deschenes M, Wong P, Krishnamurthy S, Sebastiani G. Non-alcoholic fatty liver disease in premenopausal women with polycystic ovary syndrome: A systematic review and meta-analysis. Jgh Open : An Open Access Journal of Gastroenterology and Hepatology. 5: 434-445. PMID 33860093 DOI: 10.1002/jgh3.12512  0.066
2014 Kitano S, Postow MA, Ziegler CG, Kuk D, Panageas KS, Cortez C, Rasalan T, Adamow M, Yuan J, Wong P, Altan-Bonnet G, Wolchok JD, Lesokhin AM. Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes. Cancer Immunology Research. 2: 812-21. PMID 24844912 DOI: 10.1158/2326-6066.Cir-14-0013  0.066
2015 Chen M, Chan JK, Nadarajah S, Tan AS, Chan ML, Mathew J, Saw EE, Lim C, Wong W, Cheah FS, Law HY, Wong PC, Chong SS. Single-tube nonaplex microsatellite PCR panel for preimplantation genetic diagnosis of Hb Bart's hydrops fetalis syndrome. Prenatal Diagnosis. 35: 534-43. PMID 25641621 DOI: 10.1002/pd.4568  0.065
2012 Wei H, Zhang G, Qiu S, Lu J, Sheng J, Manasi, Tan G, Wong P, Gan SU, Shim W. Hydrogen sulfide suppresses outward rectifier potassium currents in human pluripotent stem cell-derived cardiomyocytes. Plos One. 7: e50641. PMID 23226343 DOI: 10.1371/Journal.Pone.0050641  0.065
2011 Wong P, Pham R, Whitely C, Soto M, Salyers K, James C, Bruenner BA. Application of automated serial blood sampling and dried blood spot technique with liquid chromatography-tandem mass spectrometry for pharmacokinetic studies in mice. Journal of Pharmaceutical and Biomedical Analysis. 56: 604-8. PMID 21784595 DOI: 10.1016/j.jpba.2011.06.022  0.065
2010 Zhang D, He K, Raghavan N, Wang L, Crain EJ, He B, Xin B, Luettgen JM, Wong PC. Metabolism, pharmacokinetics and pharmacodynamics of the factor Xa inhibitor apixaban in rabbits. Journal of Thrombosis and Thrombolysis. 29: 70-80. PMID 19851712 DOI: 10.1007/s11239-009-0401-8  0.064
2009 Wong PC, Crain EJ, Watson CA, Hua J, Schumacher WA, Rehfuss R. Clopidogrel versus prasugrel in rabbits. Effects on thrombosis, haemostasis, platelet function and response variability. Thrombosis and Haemostasis. 101: 108-15. PMID 19132196 DOI: 10.1160/TH08-07-0456  0.064
2008 Wong P, Althammer S, Hildebrand A, Kirschner A, Pagel P, Geissler B, Smialowski P, Blöchl F, Oesterheld M, Schmidt T, Strack N, Theis FJ, Ruepp A, Frishman D. An evolutionary and structural characterization of mammalian protein complex organization. Bmc Genomics. 9: 629. PMID 19108706 DOI: 10.1186/1471-2164-9-629  0.064
2019 Ong SB, Kwek XY, Katwadi K, Hernandez-Resendiz S, Crespo-Avilan GE, Ismail NI, Lin YH, Yap EP, Lim SY, Ja KPMM, Ramachandra CJA, Tee N, Toh JJ, Shim W, Wong P, et al. Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study. International Journal of Molecular Sciences. 20. PMID 31443187 DOI: 10.3390/ijms20163972  0.064
2014 Zhang X, Jiang W, Jacutin-Porte S, Glunz PW, Zou Y, Cheng X, Nirschl AH, Wurtz NR, Luettgen JM, Rendina AR, Luo G, Harper TM, Wei A, Anumula R, Cheney DL, ... ... Wong PC, et al. Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors. Acs Medicinal Chemistry Letters. 5: 188-92. PMID 24900796 DOI: 10.1021/ml400453z  0.064
2019 Elkrief A, El Raichani L, Richard C, Messaoudene M, Belkaid W, Malo J, Belanger K, Miller W, Jamal R, Letarte N, Wong P, Routy B. Antibiotics are associated with decreased progression-free survival of advanced melanoma patients treated with immune checkpoint inhibitors. Oncoimmunology. 8: e1568812. PMID 30906663 DOI: 10.1080/2162402X.2019.1568812  0.063
2010 Wei H, Ooi TH, Tan G, Lim SY, Qian L, Wong P, Shim W. Cell delivery and tracking in post-myocardial infarction cardiac stem cell therapy: an introduction for clinical researchers. Heart Failure Reviews. 15: 1-14. PMID 19238541 DOI: 10.1007/s10741-009-9134-1  0.063
2015 Zhang F, Wang JP, Kim J, Parrish T, Wong PC. Decoding multiple sound categories in the human temporal cortex using high resolution fMRI. Plos One. 10: e0117303. PMID 25692885 DOI: 10.1371/Journal.Pone.0117303  0.063
2013 Wong PC, Ettlinger M, Zheng J. Linguistic grammar learning and DRD2-TAQ-IA polymorphism. Plos One. 8: e64983. PMID 23741438 DOI: 10.1371/Journal.Pone.0064983  0.063
2010 Dietmann S, Lee W, Wong P, Rodchenkov I, Antonov AV. CCancer: a bird's eye view on gene lists reported in cancer-related studies. Nucleic Acids Research. 38: W118-23. PMID 20529879 DOI: 10.1093/nar/gkq515  0.063
2011 Wong PC, Chan AH, Roy A, Margulis EH. The bimusical brain is not two monomusical brains in one: evidence from musical affective processing. Journal of Cognitive Neuroscience. 23: 4082-93. PMID 21812560 DOI: 10.1162/Jocn_A_00105  0.063
2016 Foin N, Ng J, Wong P, Di Mario C. Current bioresorbable scaffold technologies for treatment of coronary artery diseases: Do polymer and Magnesium platforms differ? International Journal of Cardiology. 223: 526-528. PMID 27552572 DOI: 10.1016/j.ijcard.2016.08.117  0.063
2010 Shim WS, Tan G, Gu Y, Qian L, Li S, Chung YY, Lim SY, Sim E, Chuah SC, Wong P. Dose-dependent systolic contribution of differentiated stem cells in post-infarct ventricular function. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 29: 1415-26. PMID 20688539 DOI: 10.1016/j.healun.2010.06.009  0.062
2019 Patra B, Lafontaine J, Bavoux M, Zerouali K, Glory A, Ahanj M, Carrier JF, Gervais T, Wong P. On-chip combined radiotherapy and chemotherapy testing on soft-tissue sarcoma spheroids to study cell death using flow cytometry and clonogenic assay. Scientific Reports. 9: 2214. PMID 30778138 DOI: 10.1038/s41598-019-38666-9  0.062
2009 Wong PC, Jin JX, Gunasekera GM, Abel R, Lee ER, Dhar S. Aging and cortical mechanisms of speech perception in noise. Neuropsychologia. 47: 693-703. PMID 19124032 DOI: 10.1016/J.Neuropsychologia.2008.11.032  0.061
2009 Wong PC, Perrachione TK, Margulis EH. Effects of asymmetric cultural experiences on the auditory pathway: evidence from music. Annals of the New York Academy of Sciences. 1169: 157-63. PMID 19673772 DOI: 10.1111/J.1749-6632.2009.04548.X  0.061
2011 Cantarovich M, Tchervenkov J, Paraskevas S, Ghali P, Wong P, Deschênes M, Chaudhury P, Hassanain M, Vrochides D, Metrakos P, Barkun J. Early changes in kidney function predict long-term chronic kidney disease and mortality in patients after liver transplantation. Transplantation. 92: 1358-63. PMID 22067311 DOI: 10.1097/Tp.0B013E3182384Aff  0.06
1999 Khongphatthanayothin A, Wong PC, Samara Y, Newth CJ, Wells WJ, Starnes VA, Chang AC. Impact of respiratory syncytial virus infection on surgery for congenital heart disease: postoperative course and outcome. Critical Care Medicine. 27: 1974-81. PMID 10507627  0.06
2018 Ramachandra CJA, Mehta A, Wong P, Ja KPMM, Fritsche-Danielson R, Bhat RV, Hausenloy DJ, Kovalik JP, Shim W. Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes. International Journal of Cardiology. PMID 30177232 DOI: 10.1016/j.ijcard.2018.08.069  0.06
2022 Barber Foss KD, Slutsky-Ganesh AB, Diekfuss JA, Grooms DR, Simon JE, Schneider DK, Jayanthi N, Lamplot JD, Hill D, Pombo M, Wong P, Reiter DA, Myer GD. Brain Activity During Experimental Knee Pain and Its Relationship With Kinesiophobia in Patients With Patellofemoral Pain: A Preliminary Functional Magnetic Resonance Imaging Investigation. Journal of Sport Rehabilitation. 1-10. PMID 35279019 DOI: 10.1123/jsr.2021-0236  0.06
2010 Tan G, Shim W, Gu Y, Qian L, Chung YY, Lim SY, Yong P, Sim E, Wong P. Differential effect of myocardial matrix and integrins on cardiac differentiation of human mesenchymal stem cells. Differentiation; Research in Biological Diversity. 79: 260-71. PMID 20307924 DOI: 10.1016/j.diff.2010.02.005  0.06
2003 Quan ML, Ellis CD, He MY, Liauw AY, Woerner FJ, Alexander RS, Knabb RM, Lam PY, Luettgen JM, Wong PC, Wright MR, Wexler RR. Nonbenzamidine tetrazole derivatives as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 13: 369-73. PMID 12565931 DOI: 10.1016/S0960-894X(02)00951-4  0.06
2004 Schwartz EJ, Wong P, Graydon RJ. Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy. The Journal of Urology. 171: 771-4. PMID 14713808 DOI: 10.1097/01.ju.0000106970.97082.61  0.059
2002 Wong PC. Hemispheric specialization of linguistic pitch patterns. Brain Research Bulletin. 59: 83-95. PMID 12379438 DOI: 10.1016/S0361-9230(02)00860-2  0.059
2013 Wong P, Johnson KJ, Warner RL, Merz SI, Kruger GH, Weitzel WF. Performance of Biopsy Needle With Therapeutic Injection System to Prevent Bleeding Complications. Journal of Medical Devices. 7: 110021-110027. PMID 23917874 DOI: 10.1115/1.4023274  0.059
2022 Sebastiani G, Milic J, Cervo A, Saeed S, Krahn T, Kablawi D, Al Hinai AS, Lebouché B, Wong P, Deschenes M, Gioè C, Cascio A, Mazzola G, Guaraldi G. Two-Tier Care Pathways for Liver Fibrosis Associated to Non-Alcoholic Fatty Liver Disease in HIV Mono-Infected Patients. Journal of Personalized Medicine. 12. PMID 35207770 DOI: 10.3390/jpm12020282  0.059
2014 Hangeland JJ, Friends TJ, Rossi KA, Smallheer JM, Wang C, Sun Z, Corte JR, Fang T, Wong PC, Rendina AR, Barbera FA, Bozarth JM, Luettgen JM, Watson CA, Zhang G, et al. Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity. Journal of Medicinal Chemistry. 57: 9915-32. PMID 25405503 DOI: 10.1021/jm5010607  0.058
2016 Smialowski P, Wong P. Protein Crystallizability. Methods in Molecular Biology (Clifton, N.J.). 1415: 341-70. PMID 27115641 DOI: 10.1007/978-1-4939-3572-7_17  0.058
2012 Al-Busafi SA, Bhat M, Wong P, Ghali P, Deschenes M. Antioxidant therapy in nonalcoholic steatohepatitis. Hepatitis Research and Treatment. 2012: 947575. PMID 23227320 DOI: 10.1155/2012/947575  0.058
2005 Pagel P, Wong P, Frishman D. A domain interaction map based on phylogenetic profiling. Journal of Molecular Biology. 344: 1331-46. PMID 15561146 DOI: 10.1016/j.jmb.2004.10.019  0.057
2010 Wong PC, Ettlinger M, Sheppard JP, Gunasekera GM, Dhar S. Neuroanatomical characteristics and speech perception in noise in older adults. Ear and Hearing. 31: 471-9. PMID 20588117 DOI: 10.1097/Aud.0B013E3181D709C2  0.057
2020 Lafontaine J, Boisvert JS, Glory A, Coulombe S, Wong P. Synergy between Non-Thermal Plasma with Radiation Therapy and Olaparib in a Panel of Breast Cancer Cell Lines. Cancers. 12. PMID 32033118 DOI: 10.3390/cancers12020348  0.057
2022 Yuan Y, Wong P, Butler JP, Henden A, Curley C, Durrant S, Mediwake H, Morton AJ, Stewart C, Subramoniapillai E, Weber N, Tey SK, Kennedy GA, Scott AP. High incidence of resistant breakthrough invasive fungal infections (IFD) in patients treated for acute gastrointestinal graft-versus-host disease (GI GVHD) following allogeneic haematopoietic cell transplantation. Bone Marrow Transplantation. PMID 35970876 DOI: 10.1038/s41409-022-01773-9  0.057
2007 Wong PC, Skoe E, Russo NM, Dees T, Kraus N. Musical experience shapes human brainstem encoding of linguistic pitch patterns. Nature Neuroscience. 10: 420-2. PMID 17351633 DOI: 10.1038/Nn1872  0.057
2023 Kibel S, Kuehne N, Ribeiro MF, Muniz TP, Ye XY, Spreafico A, Saibil SD, Sun A, Mak DY, Gray D, Jones B, Wong P, Butler MO. The Role of Adjuvant Radiotherapy for the Treatment of Resected High-Risk Stage III Cutaneous Melanoma in the Era of Modern Systemic Therapies. Cancers. 15. PMID 38136412 DOI: 10.3390/cancers15245867  0.057
2003 Wong P, Kolesov G, Frishman D, Houry WA. Phylogenetic web profiler. Bioinformatics (Oxford, England). 19: 782-3. PMID 12691995 DOI: 10.1093/Bioinformatics/Btg064  0.057
2002 Batra AS, Acherman RJ, Wong WY, Wood JC, Chan LS, Ramicone E, Ebrahimi M, Wong PC. Cardiac abnormalities in children with sickle cell anemia. American Journal of Hematology. 70: 306-12. PMID 12210812 DOI: 10.1002/ajh.10154  0.056
2012 Evans JE, Jungjohann KL, Wong PC, Chiu PL, Dutrow GH, Arslan I, Browning ND. Visualizing macromolecular complexes with in situ liquid scanning transmission electron microscopy. Micron (Oxford, England : 1993). 43: 1085-90. PMID 22386621 DOI: 10.1016/J.Micron.2012.01.018  0.056
2016 Wong P, Leppert IR, Roberge D, Boudam K, Brown PD, Muanza T, Pike GB, Chankowsky J, Mihalcioiu C. A pilot study using dynamic contrast enhanced-MRI as a response biomarker of the radioprotective effect of memantine in patients receiving whole brain radiotherapy. Oncotarget. PMID 27248467 DOI: 10.18632/Oncotarget.9653  0.056
2009 Wong PC, Crain EJ, Watson CA, Xin B. Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits. Journal of Thrombosis and Haemostasis : Jth. 7: 1313-20. PMID 19500242 DOI: 10.1111/j.1538-7836.2009.03503.x  0.056
2013 Glunz PW, Zhang X, Zou Y, Delucca I, Nirschl AH, Cheng X, Weigelt CA, Cheney DL, Wei A, Anumula R, Luettgen JM, Rendina AR, Harpel M, Luo G, Knabb R, ... Wong PC, et al. Nonbenzamidine acylsulfonamide tissue factor-factor VIIa inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 5244-8. PMID 23845220 DOI: 10.1016/j.bmcl.2013.06.027  0.056
2000 Wong PC, Crain EJ, Knabb RM, Meade RP, Quan ML, Watson CA, Wexler RR, Wright MR, Slee AM. Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis. The Journal of Pharmacology and Experimental Therapeutics. 295: 212-8. PMID 10991981  0.056
2007 Perrachione TK, Wong PC. Learning to recognize speakers of a non-native language: implications for the functional organization of human auditory cortex. Neuropsychologia. 45: 1899-910. PMID 17258240 DOI: 10.1016/J.Neuropsychologia.2006.11.015  0.056
2013 Zhang X, Glunz PW, Jiang W, Schmitt A, Newman M, Barbera FA, Bozarth JM, Rendina AR, Wei A, Wen X, Rossi KA, Luettgen JM, Wong PC, Knabb RM, Wexler RR, et al. Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 1604-7. PMID 23416003 DOI: 10.1016/j.bmcl.2013.01.094  0.056
2015 El-Bared N, Wong P, Wang D. Soft tissue sarcoma and radiation therapy advances, impact on toxicity. Current Treatment Options in Oncology. 16: 19. PMID 25859829 DOI: 10.1007/s11864-015-0335-7  0.055
2017 Chennouf A, Arslanian E, Roberge D, Berthelet F, Bojanowski M, Bahary JP, Masucci L, Belanger K, Florescu M, Wong P. Efficiency of Crizotinib on an ALK-Positive Inflammatory Myofibroblastic Tumor of the Central Nervous System: A Case Report. Cureus. 9: e1068. PMID 28409069 DOI: 10.7759/cureus.1068  0.055
2004 Lam MF, Ooi GC, Lam B, Ho JC, Seto WH, Ho PL, Wong PC, Liang R, Lam WK, Tsang KW. An indolent case of severe acute respiratory syndrome. American Journal of Respiratory and Critical Care Medicine. 169: 125-8. PMID 14695107 DOI: 10.1164/rccm.200306-754CR  0.055
2012 Wei H, Tan G, Qiu S, Kong G, Yong P, Koh C, Ooi TH, Lim SY, Wong P, Gan SU, Shim W. One-step derivation of cardiomyocytes and mesenchymal stem cells from human pluripotent stem cells. Stem Cell Research. 9: 87-100. PMID 22683798 DOI: 10.1016/j.scr.2012.04.003  0.055
2014 Mehta A, Sequiera GL, Ramachandra CJ, Sudibyo Y, Chung Y, Sheng J, Wong KY, Tan TH, Wong P, Liew R, Shim W. Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes. Cardiovascular Research. 102: 497-506. PMID 24623279 DOI: 10.1093/cvr/cvu060  0.055
2016 Ang HY, Bulluck H, Wong P, Venkatraman SS, Huang Y, Foin N. Bioresorbable stents: Current and upcoming bioresorbable technologies. International Journal of Cardiology. 228: 931-939. PMID 27912202 DOI: 10.1016/j.ijcard.2016.11.258  0.055
2015 Antoniou M, Wong PC. Poor phonetic perceivers are affected by cognitive load when resolving talker variability. The Journal of the Acoustical Society of America. 138: 571. PMID 26328675 DOI: 10.1121/1.4923362  0.054
2007 Wong PC, Crain EJ, Watson CA, Wexler RR, Lam PY, Quan ML, Knabb RM. Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits. Journal of Thrombosis and Thrombolysis. 24: 43-51. PMID 17323133 DOI: 10.1007/s11239-007-0017-9  0.054
2004 Wong PC, Nusbaum HC, Small SL. Neural bases of talker normalization. Journal of Cognitive Neuroscience. 16: 1173-84. PMID 15453972 DOI: 10.1162/0898929041920522  0.054
2000 Galemmo RA, Wells BL, Rossi KA, Alexander RS, Dominguez C, Maduskuie TP, Stouten PF, Wright MR, Aungst BJ, Wong PC, Knabb RM, Wexler RR. The de novo design and synthesis of cyclic urea inhibitors of factor Xa: optimization of the S4 ligand. Bioorganic & Medicinal Chemistry Letters. 10: 301-4. PMID 10698459 DOI: 10.1016/S0960-894X(99)00688-5  0.054
2012 Mehta A, Chung Y, Sequiera GL, Wong P, Liew R, Shim W. Pharmacoelectrophysiology of viral-free induced pluripotent stem cell-derived human cardiomyocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 458-69. PMID 23091167 DOI: 10.1093/toxsci/kfs309  0.053
2012 Qian L, Shim W, Gu Y, Shirhan M, Lim KP, Tan LP, Lim CH, Sin YK, Wong P. Hemodynamic contribution of stem cell scaffolding in acute injured myocardium. Tissue Engineering. Part A. 18: 1652-63. PMID 22607369 DOI: 10.1089/ten.TEA.2011.0591  0.053
2012 Sheppard JP, Wang JP, Wong PC. Large-scale cortical network properties predict future sound-to-word learning success. Journal of Cognitive Neuroscience. 24: 1087-103. PMID 22360625 DOI: 10.1162/Jocn_A_00210  0.053
2015 Hannani D, Vétizou M, Enot D, Rusakiewicz S, Chaput N, Klatzmann D, Desbois M, Jacquelot N, Vimond N, Chouaib S, Mateus C, Allison JP, Ribas A, Wolchok JD, Yuan J, ... Wong P, et al. Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25. Cell Research. 25: 208-24. PMID 25582080 DOI: 10.1038/Cr.2015.3  0.053
2012 Wong PC, Ciocca V, Chan AH, Ha LY, Tan LH, Peretz I. Effects of culture on musical pitch perception. Plos One. 7: e33424. PMID 22509257 DOI: 10.1371/Journal.Pone.0033424  0.053
2008 Tam WO, Wong CF, Wong PC. Endobronchial nocardiosis associated with broncholithiasis. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Universitã  Di Napoli, Secondo Ateneo. 69: 183-5. PMID 19350841 DOI: 10.4081/MONALDI.2008.381  0.052
2022 Wong P, Akrami A, Houk B, Vuu I, James CA. Validation of an LC-MS/MS method for the determination of sotorasib, a KRAS inhibitor, in human plasma. Bioanalysis. 14: 1281-1292. PMID 36473022 DOI: 10.4155/bio-2022-0173  0.052
2023 Zoughlami A, Serero J, Congly S, Zhao I, Zhu J, Ramji A, Cooper C, Wong P, Bailey R, Coffin CS, Sebastiani G. Diagnosis of esophageal varices by liver stiffness and serum biomarkers in virus-related compensated advanced chronic liver disease. Canadian Liver Journal. 6: 332-346. PMID 38020192 DOI: 10.3138/canlivj-2022-0047  0.052
2012 Chandrasekaran B, Kraus N, Wong PC. Human inferior colliculus activity relates to individual differences in spoken language learning. Journal of Neurophysiology. 107: 1325-36. PMID 22131377 DOI: 10.1152/Jn.00923.2011  0.052
2008 Corte JR, Fang T, Pinto DJ, Han W, Hu Z, Jiang XJ, Li YL, Gauuan JF, Hadden M, Orton D, Rendina AR, Luettgen JM, Wong PC, He K, Morin PE, et al. Structure-activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties. Bioorganic & Medicinal Chemistry Letters. 18: 2845-9. PMID 18424044 DOI: 10.1016/j.bmcl.2008.03.092  0.052
2009 Mitsuyasu RT, Merigan TC, Carr A, Zack JA, Winters MA, Workman C, Bloch M, Lalezari J, Becker S, Thornton L, Akil B, Khanlou H, Finlayson R, McFarlane R, Smith DE, ... ... Wong P, et al. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells. Nature Medicine. 15: 285-92. PMID 19219022 DOI: 10.1038/Nm.1932  0.052
2023 Congly SE, Marquez V, Bhanji RA, Bhat M, Wong P, Huard G, Zhu JH, Brahmania M. Exception points for liver transplantation: A Canadian review. Canadian Liver Journal. 6: 201-214. PMID 37503519 DOI: 10.3138/canlivj-2022-0026  0.052
2015 Priestley ES, Cheney DL, DeLucca I, Wei A, Luettgen JM, Rendina AR, Wong PC, Wexler RR. Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors. Journal of Medicinal Chemistry. 58: 6225-36. PMID 26151189 DOI: 10.1021/acs.jmedchem.5b00788  0.052
2015 Priestley ES, Cheney DL, DeLucca I, Wei A, Luettgen JM, Rendina AR, Wong PC, Wexler RR. Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors Journal of Medicinal Chemistry. 58: 6225-6236. DOI: 10.1021/acs.jmedchem.5b00788  0.052
2018 Viswanathan SK, Puckelwartz MJ, Mehta A, Ramachandra CJA, Jagadeesan A, Fritsche-Danielson R, Bhat RV, Wong P, Kandoi S, Schwanekamp JA, Kuffel G, Pesce LL, Zilliox MJ, Durai UNB, Verma RS, et al. Association of Cardiomyopathy With MYBPC3 D389V and MYBPC3Δ25bpIntronic Deletion in South Asian Descendants. Jama Cardiology. PMID 29641836 DOI: 10.1001/Jamacardio.2018.0618  0.052
2002 Wong PC, Pinto DJ, Knabb RM. Nonpeptide factor Xa inhibitors: DPC423, a highly potent and orally bioavailable pyrazole antithrombotic agent. Cardiovascular Drug Reviews. 20: 137-52. PMID 12177691  0.051
2024 Chermat R, Refet-Mollof E, Kamio Y, Carrier JF, Wong P, Gervais T. Brachytherapy on-a-chip: a clinically-relevant approach for radiotherapy testing in 3d biology. Lab On a Chip. PMID 38568477 DOI: 10.1039/d4lc00032c  0.051
2013 Priestley ES, De Lucca I, Zhou J, Zhou J, Saiah E, Stanton R, Robinson L, Luettgen JM, Wei A, Wen X, Knabb RM, Wong PC, Wexler RR. Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor. Bioorganic & Medicinal Chemistry Letters. 23: 2432-5. PMID 23478148 DOI: 10.1016/j.bmcl.2013.02.013  0.051
2010 Schumacher WA, Bostwick JS, Stewart AB, Steinbacher TE, Xin B, Wong PC. Effect of the direct factor Xa inhibitor apixaban in rat models of thrombosis and hemostasis. Journal of Cardiovascular Pharmacology. 55: 609-16. PMID 20224421 DOI: 10.1097/FJC.0b013e3181daded3  0.051
2014 Liu F, Maggu AR, Lau JC, Wong PC. Brainstem encoding of speech and musical stimuli in congenital amusia: evidence from Cantonese speakers. Frontiers in Human Neuroscience. 8: 1029. PMID 25646077 DOI: 10.3389/Fnhum.2014.01029  0.051
2012 O'Sullivan B, Dickie C, Catton C, Chung P, Wong P, Griffin A, Wunder J, Ferguson P, Bell R. In regard to RTOG sarcoma radiation oncologists reach consensus on gross tumor volume and clinical target volume on computed tomographic images for preoperative radiotherapy of primary soft tissue sarcoma of extremity in Radiation Therapy Oncology Group studies: in regard to Wang et al (Int J Radiat Oncol Biol Phys 2011;81:e525-e528). International Journal of Radiation Oncology, Biology, Physics. 83: 483. PMID 22579375 DOI: 10.1016/j.ijrobp.2012.01.059  0.051
2011 Wong FC, Chandrasekaran B, Garibaldi K, Wong PC. White matter anisotropy in the ventral language pathway predicts sound-to-word learning success. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8780-5. PMID 21677162 DOI: 10.1523/Jneurosci.0999-11.2011  0.05
2000 Pruitt JR, Pinto DJ, Estrella MJ, Bostrom LL, Knabb RM, Wong PC, Wright MR, Wexler RR. Isoxazolines and isoxazoles as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 10: 685-9. PMID 10782664 DOI: 10.1016/S0960-894X(00)00097-4  0.05
2018 Lowery MA, Bradley M, Chou JF, Capanu M, Gerst S, Harding JJ, Dika IE, Berger M, Zehir A, Ptashkin R, Wong P, Rasalan-Ho T, Yu KH, Cercek A, Morgono E, et al. Binimetinib plus Gemcitabine and Cisplatin Phase I/II Trial in Patients with Advanced Biliary Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30563938 DOI: 10.1158/1078-0432.Ccr-18-1927  0.05
2007 Pinto DJ, Orwat MJ, Koch S, Rossi KA, Alexander RS, Smallwood A, Wong PC, Rendina AR, Luettgen JM, Knabb RM, He K, Xin B, Wexler RR, Lam PY. Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. Journal of Medicinal Chemistry. 50: 5339-56. PMID 17914785 DOI: 10.1021/jm070245n  0.05
2008 Song JH, Skoe E, Wong PC, Kraus N. Plasticity in the adult human auditory brainstem following short-term linguistic training. Journal of Cognitive Neuroscience. 20: 1892-902. PMID 18370594 DOI: 10.1162/Jocn.2008.20131  0.05
2000 Wong PC, Quan ML, Crain EJ, Watson CA, Wexler RR, Knabb RM. Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics. The Journal of Pharmacology and Experimental Therapeutics. 292: 351-7. PMID 10604970  0.05
2015 Smith LM, Orwat MJ, Hu Z, Han W, Wang C, Rossi KA, Gilligan PJ, Pabbisetty KB, Osuna H, Corte JR, Rendina AR, Luettgen JM, Wong PC, Narayanan R, Harper TW, et al. Novel phenylalanine derived diamides as Factor XIa inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 26704266 DOI: 10.1016/j.bmcl.2015.11.089  0.049
1999 Yew WW, Wong PC, Lee J, Fung SL, Wong CF, Chan CY. Report of eight cases of pulmonary actinomycosis and their treatment with imipenem-cilastatin. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Universitã  Di Napoli, Secondo Ateneo. 54: 126-9. PMID 10394825  0.049
2022 Lafontaine J, Refet-Mollof E, Najyb O, Gervais T, Wong P. Cell Death Analysis in Cancer Spheroids from a Microfluidic Device. Methods in Molecular Biology (Clifton, N.J.). 2543: 13-25. PMID 36087255 DOI: 10.1007/978-1-0716-2553-8_2  0.049
2020 Kosik I, Brackstone M, Kornecki A, Chamson-Reig A, Wong P, Carson JJL. Lipid-weighted intraoperative photoacoustic tomography of breast tumors: Volumetric comparison to preoperative MRI. Photoacoustics. 18: 100165. PMID 32426228 DOI: 10.1016/j.pacs.2020.100165  0.049
2004 Fong CY, Sathananthan AH, Wong PC, Bongso A. Nine-day-old human embryo cultured in vitro: a clue to the origins of embryonic stem cells. Reproductive Biomedicine Online. 9: 321-5. PMID 15353084  0.049
2006 del Castillo SL, Moromisato DY, Dorey F, Ludwick J, Starnes VA, Wells WJ, Jeffries HE, Wong PC. Mesenteric blood flow velocities in the newborn with single-ventricle physiology: modified Blalock-Taussig shunt versus right ventricle-pulmonary artery conduit. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 7: 132-7. PMID 16474253 DOI: 10.1097/01.PCC.0000200999.89777.92  0.049
2014 Quan ML, Wong PC, Wang C, Woerner F, Smallheer JM, Barbera FA, Bozarth JM, Brown RL, Harpel MR, Luettgen JM, Morin PE, Peterson T, Ramamurthy V, Rendina AR, Rossi KA, et al. Tetrahydroquinoline derivatives as potent and selective factor XIa inhibitors. Journal of Medicinal Chemistry. 57: 955-69. PMID 24405333 DOI: 10.1021/jm401670x  0.049
2014 Walsh-Messinger J, Ramirez PM, Wong P, Antonius D, Aujero N, McMahon K, Opler LA, Malaspina D. Impairment in emotional modulation of attention and memory in schizophrenia. Schizophrenia Research. 157: 63-9. PMID 24910446 DOI: 10.1016/J.Schres.2014.05.014  0.048
2006 Pinto DJ, Orwat MJ, Quan ML, Han Q, Galemmo RA, Amparo E, Wells B, Ellis C, He MY, Alexander RS, Rossi KA, Smallwood A, Wong PC, Luettgen JM, Rendina AR, et al. 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 16: 4141-7. PMID 16730984 DOI: 10.1016/j.bmcl.2006.02.069  0.048
2014 Moe KT, Khairunnisa K, Yin NO, Chin-Dusting J, Wong P, Wong MC. Tumor necrosis factor-α-induced nuclear factor-kappaB activation in human cardiomyocytes is mediated by NADPH oxidase. Journal of Physiology and Biochemistry. 70: 769-79. PMID 25059721 DOI: 10.1007/s13105-014-0345-0  0.048
2017 Brunet AR, Labelle F, Wong P, Gervais T. Reconfigurable Microfluidic Magnetic Valve Arrays: Towards a Radiotherapy-Compatible Spheroid Culture Platform for the Combinatorial Screening of Cancer Therapies. Sensors (Basel, Switzerland). 17. PMID 28976942 DOI: 10.3390/s17102271  0.048
2012 Wong P, Lambert C, Agnihotram RV, David M, Duclos M, Freeman CR. Ductal carcinoma in situ--the influence of the radiotherapy boost on local control. International Journal of Radiation Oncology, Biology, Physics. 82: e153-8. PMID 21664063 DOI: 10.1016/j.ijrobp.2011.03.045  0.048
2021 Wong P, Chatrapati R, Williams S, McGrath K, Millard G, Liew YW, Baidya S. A Houdini act: Transient loss of Jka resulting in anti-Jk3 antibody formation. Transfusion Medicine (Oxford, England). PMID 33709488 DOI: 10.1111/tme.12770  0.048
2003 Lam PY, Clark CG, Li R, Pinto DJ, Orwat MJ, Galemmo RA, Fevig JM, Teleha CA, Alexander RS, Smallwood AM, Rossi KA, Wright MR, Bai SA, He K, Luettgen JM, ... Wong PC, et al. Structure-based design of novel guanidine/benzamidine mimics: potent and orally bioavailable factor Xa inhibitors as novel anticoagulants. Journal of Medicinal Chemistry. 46: 4405-18. PMID 14521405 DOI: 10.1021/jm020578e  0.048
2015 Bhat M, Wyse JM, Moodie E, Ghali P, Hilzenrat N, Wong P, Deschenes M. Prevalence and predictors of sleep disturbance among liver diseases in long-term transplant survivors. Canadian Journal of Gastroenterology & Hepatology. PMID 26176212  0.048
2017 Dorion V, Lambert L, Frazzi A, Cayer JF, Wong P. A Pilot Study in the Use of Activity Trackers for Assessing Response to Palliative Radiotherapy. Cureus. 9: e1871. PMID 29383293 DOI: 10.7759/cureus.1871  0.047
2015 Wong PC, Watson C, Crain EJ. The P2Y1 receptor antagonist MRS2500 prevents carotid artery thrombosis in cynomolgus monkeys. Journal of Thrombosis and Thrombolysis. PMID 26660522 DOI: 10.1007/s11239-015-1302-7  0.047
2007 Sherman M, Shafran S, Burak K, Doucette K, Wong W, Girgrah N, Yoshida E, Renner E, Wong P, Deschênes M. Management of chronic hepatitis B: consensus guidelines. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 21: 5C-24C. PMID 17568823  0.047
2012 Al-Busafi SA, Ghali P, Wong P, Novales-Diaz JA, Deschênes M. The utility of Xenon-133 liver scan in the diagnosis and management of nonalcoholic fatty liver disease. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 26: 155-9. PMID 22408767  0.047
2003 Pruitt JR, Pinto DJ, Galemmo RA, Alexander RS, Rossi KA, Wells BL, Drummond S, Bostrom LL, Burdick D, Bruckner R, Chen H, Smallwood A, Wong PC, Wright MR, Bai S, et al. Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1). Journal of Medicinal Chemistry. 46: 5298-315. PMID 14640539 DOI: 10.1021/jm030212h  0.047
1999 Dominguez C, Duffy DE, Han Q, Alexander RS, Galemmo RA, Park JM, Wong PC, Amparo EC, Knabb RM, Luettgen J, Wexler RR. Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 9: 925-30. PMID 10230612  0.047
2018 Ang HY, Toong D, Chow WS, Seisilya W, Wu W, Wong P, Venkatraman SS, Foin N, Huang Y. Radiopaque Fully Degradable Nanocomposites for Coronary Stents. Scientific Reports. 8: 17409. PMID 30479353 DOI: 10.1038/s41598-018-35663-2  0.047
2017 Mengdi Xu, Jun Cheng, Annan Li, Lee JA, Wong DWK, Taruya A, Tanaka A, Foin N, Wong P. Fibroatheroma identification in Intravascular Optical Coherence Tomography images using deep features. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2017: 1501-1504. PMID 29060164 DOI: 10.1109/EMBC.2017.8037120  0.046
2017 Tiberi D, Masucci L, Shedid D, Roy I, Vu T, Patocskai E, Robidoux A, Wong P. Limitations of Personalized Medicine and Gene Assays for Breast Cancer. Cureus. 9: e1100. PMID 28428927 DOI: 10.7759/cureus.1100  0.046
2015 Wong PC, Quan ML, Watson CA, Crain EJ, Harpel MR, Rendina AR, Luettgen JM, Wexler RR, Schumacher WA, Seiffert DA. In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa Journal of Thrombosis and Thrombolysis. DOI: 10.1007/s11239-015-1258-7  0.046
2015 Hu Z, Wong PC, Gilligan PJ, Han W, Pabbisetty KB, Bozarth JM, Crain EJ, Harper T, Luettgen JM, Myers JE, Ramamurthy V, Rossi KA, Sheriff S, Watson CA, Wei A, et al. Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety. Acs Medicinal Chemistry Letters. 6: 590-5. PMID 26005539 DOI: 10.1021/acsmedchemlett.5b00066  0.046
1996 WONG PC. DETECTION OF CLOSTRIDIUM BOTULINUM TYPE E TOXIN BY MONOCLONAL ANTIBODY ENZYME IMMUNOASSAY Journal of Rapid Methods and Automation in Microbiology. 4: 191-206. DOI: 10.1111/J.1745-4581.1996.TB00123.X  0.046
2005 Quan ML, Lam PY, Han Q, Pinto DJ, He MY, Li R, Ellis CD, Clark CG, Teleha CA, Sun JH, Alexander RS, Bai S, Luettgen JM, Knabb RM, Wong PC, et al. Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor. Journal of Medicinal Chemistry. 48: 1729-44. PMID 15771420 DOI: 10.1021/jm0497949  0.046
2003 Quan ML, Ellis CD, He MY, Liauw AY, Lam PY, Rossi KA, Knabb RM, Luettgen JM, Wright MR, Wong PC, Wexler RR. Nonbenzamidine isoxazoline derivatives as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 13: 1023-8. PMID 12643903 DOI: 10.1016/S0960-894X(03)00080-5  0.045
2015 Luk CC, Tam LS, Kwan BC, Wong PC, Ma TK, Chow KM, Lai FM, Li PK, Szeto CC. Intrarenal and Urinary Th9 and Th22 Cytokine Gene Expression in Lupus Nephritis. The Journal of Rheumatology. PMID 25979722 DOI: 10.3899/Jrheum.140954  0.045
2022 Chermat R, Ziaee M, Mak DY, Refet-Mollof E, Rodier F, Wong P, Carrier JF, Kamio Y, Gervais T. Radiotherapy on-chip: microfluidics for translational radiation oncology. Lab On a Chip. PMID 35477748 DOI: 10.1039/d2lc00177b  0.045
2015 Encarnação LM, Chuang YY, Stork A, Kasik D, Rhyne TM, Avila L, Kohlhammer J, LaViola JJ, Tory M, Dill J, Domik G, Owen GS, Wong PC. Future directions in computer graphics and visualization: From CG&A's editorial board Ieee Computer Graphics and Applications. 35: 20-32. DOI: 10.1109/Mcg.2015.14  0.045
2011 Mehta A, Chung YY, Ng A, Iskandar F, Atan S, Wei H, Dusting G, Sun W, Wong P, Shim W. Pharmacological response of human cardiomyocytes derived from virus-free induced pluripotent stem cells. Cardiovascular Research. 91: 577-86. PMID 21565833 DOI: 10.1093/cvr/cvr132  0.045
2007 Wong PC, Perrachione TK, Parrish TB. Neural characteristics of successful and less successful speech and word learning in adults. Human Brain Mapping. 28: 995-1006. PMID 17133399 DOI: 10.1002/Hbm.20330  0.045
2022 Cheung R, Ito E, Lopez M, Rubinstein E, Keller H, Cheung F, Liu ZA, Liu FF, Wong P. Evaluating the Short-Term Environmental and Clinical Effects of a Radiation Oncology Department's Response to the COVID-19 Pandemic (STEER COVID-19). International Journal of Radiation Oncology, Biology, Physics. PMID 36309074 DOI: 10.1016/j.ijrobp.2022.04.054  0.045
2013 Zhang GQ, Wei H, Lu J, Wong P, Shim W. Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells. Plos One. 8: e55266. PMID 23408964 DOI: 10.1016/S0735-1097(12)60963-2  0.045
2009 Jiang X, Crain EJ, Luettgen JM, Schumacher WA, Wong PC. Apixaban, an oral direct factor Xa inhibitor, inhibits human clot-bound factor Xa activity in vitro. Thrombosis and Haemostasis. 101: 780-2. PMID 19350128  0.045
2009 Smialowski P, Pagel P, Wong P, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Rattei T, Frishman D, Ruepp A. The Negatome database: A reference set of non-interacting protein pairs Nucleic Acids Research. 38: D540-D544. PMID 19920129 DOI: 10.1093/nar/gkp1026  0.045
2003 Ho JC, Ooi GC, Mok TY, Chan JW, Hung I, Lam B, Wong PC, Li PC, Ho PL, Lam WK, Ng CK, Ip MS, Lai KN, Chan-Yeung M, Tsang KW. High-dose pulse versus nonpulse corticosteroid regimens in severe acute respiratory syndrome. American Journal of Respiratory and Critical Care Medicine. 168: 1449-56. PMID 12947028 DOI: 10.1164/rccm.200306-766OC  0.044
2022 Kallas ON, Nezami N, Singer AD, Wong P, Kokabi N, Bercu ZL, Umpierrez M, Tran A, Reimer NB, Oskouei SV, Gonzalez FM. Cooled Radiofrequency Ablation for Chronic Joint Pain Secondary to Hip and Shoulder Osteoarthritis. Radiographics : a Review Publication of the Radiological Society of North America, Inc. 210074. PMID 35148246 DOI: 10.1148/rg.210074  0.044
2001 Yoshiyama Y, Yazaki T, Wong PC, Beauchamp D, Kanke M. The effect of fosfomycin on glycopeptide antibiotic-induced nephrotoxicity in rats. Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. 7: 243-6. PMID 11810591 DOI: 10.1007/S101560170020  0.044
2002 Richards M, Fong CY, Chan WK, Wong PC, Bongso A. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nature Biotechnology. 20: 933-6. PMID 12161760 DOI: 10.1038/nbt726  0.044
2006 Leung AW, Chan CC, Ng JJ, Wong PC. Factors contributing to officers' fatigue in high-speed maritime craft operations. Applied Ergonomics. 37: 565-76. PMID 16368069 DOI: 10.1016/j.apergo.2005.11.003  0.044
2007 Qiao JX, Cheng X, Smallheer JM, Galemmo RA, Drummond S, Pinto DJ, Cheney DL, He K, Wong PC, Luettgen JM, Knabb RM, Wexler RR, Lam PY. Pyrazole-based factor Xa inhibitors containing N-arylpiperidinyl P4 residues. Bioorganic & Medicinal Chemistry Letters. 17: 1432-7. PMID 17174550 DOI: 10.1016/j.bmcl.2006.11.071  0.044
2009 Perrachione TK, Pierrehumbert JB, Wong PC. Differential neural contributions to native- and foreign-language talker identification. Journal of Experimental Psychology. Human Perception and Performance. 35: 1950-60. PMID 19968445 DOI: 10.1037/A0015869  0.044
2003 Tsang KW, Mok TY, Wong PC, Ooi GC. Severe acute respiratory syndrome (SARS) in Hong Kong. Respirology (Carlton, Vic.). 8: 259-65. PMID 14528875 DOI: 10.1046/j.1440-1843.2003.00486.x  0.043
1998 Wong CF, Yew WW, Wong PC, Lee J. A case of concomitant tuberculosis and sarcoidosis with mycobacterial DNA present in the sarcoid lesion. Chest. 114: 626-9. PMID 9726757  0.043
2023 Nguyen DD, Bouhadana D, Wong P, Andonian S. What is the prevalence of hepatic steatosis on ultrasonography in patients followed for nephrolithiasis? Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada. 16: 442-446. PMID 36656689 DOI: 10.5489/cuaj.7767  0.043
2017 Ang HY, Huang YY, Lim ST, Wong P, Joner M, Foin N. Mechanical behavior of polymer-based vs. metallic-based bioresorbable stents. Journal of Thoracic Disease. 9: S923-S934. PMID 28894598 DOI: 10.21037/jtd.2017.06.30  0.042
2014 Perrachione TK, Stepp CE, Hillman RE, Wong PC. Talker identification across source mechanisms: experiments with laryngeal and electrolarynx speech. Journal of Speech, Language, and Hearing Research : Jslhr. 57: 1651-65. PMID 24801962 DOI: 10.1044/2014_Jslhr-S-13-0161  0.042
2008 Wong PC, Warrier CM, Penhune VB, Roy AK, Sadehh A, Parrish TB, Zatorre RJ. Volume of left Heschl's Gyrus and linguistic pitch learning. Cerebral Cortex (New York, N.Y. : 1991). 18: 828-36. PMID 17652466 DOI: 10.1093/Cercor/Bhm115  0.042
2006 Shim WS, Li W, Zhang L, Li S, Ong HC, Song IC, Bapna A, Ge R, Lim YT, Chuah SC, Sim EK, Wong P. Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model. Journal of Biomedical Science. 13: 579-91. PMID 16547766 DOI: 10.1007/s11373-006-9082-x  0.042
1999 Fevig JM, Buriak J, Stouten PF, Knabb RM, Lam GN, Wong PC, Wexler RR. Preparation of pyrrolidine and isoxazolidine benzamidines as potent inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 9: 1195-200. PMID 10328312  0.042
2001 Wong PC, Fung SL, Lee J, Wong CF, Chau CH, Yew WW. Chronic necrotizing pulmonary aspergillosis. A report of 9 cases with analysis of clinical picture, risk factors and treatment for outcome correlation. Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro, Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio, Universitã  Di Napoli, Secondo Ateneo. 56: 202-7. PMID 11665498  0.042
2015 Chen T, Wong R, Wong P, Rollet-Kurhajec KC, Alshaalan R, Deschenes M, Ghali P, Sebastiani G. Occult cirrhosis diagnosed by transient elastography is a frequent and under-monitored clinical entity. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 25676459 DOI: 10.1111/liv.12802  0.042
2016 Jiang J, James CA, Wong P. Bioanalytical method development and validation for the determination of glycine in human cerebrospinal fluid by ion-pair reversed-phase liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 128: 132-140. PMID 27262106 DOI: 10.1016/j.jpba.2016.05.019  0.042
2022 Alhinai A, Qayyum-Khan A, Zhang X, Samaha P, Metrakos P, Deschenes M, Wong P, Ghali P, Chen TY, Sebastiani G. Non-alcoholic steatohepatitis in liver transplant recipients diagnosed by serum cytokeratin 18 and transient elastography: A prospective study. World Journal of Hepatology. 13: 2179-2191. PMID 35070018 DOI: 10.4254/wjh.v13.i12.2179  0.042
2003 Wong PC, Diehl RL. Perceptual normalization for inter- and intratalker variation in Cantonese level tones. Journal of Speech, Language, and Hearing Research : Jslhr. 46: 413-21. PMID 14700382 DOI: 10.1044/1092-4388(2003/034)  0.041
2012 Frommelt PC, Guey LT, Minich LL, Bhat M, Bradley TJ, Colan SD, Ensing G, Gorentz J, Heydarian H, John JB, Lai WW, Levine JC, Mahle WT, Miller SG, Ohye RG, ... ... Wong PC, et al. Does initial shunt type for the Norwood procedure affect echocardiographic measures of cardiac size and function during infancy?: the Single Vventricle Reconstruction trial. Circulation. 125: 2630-8. PMID 22523314 DOI: 10.1161/CIRCULATIONAHA.111.072694  0.041
2013 Wong PC, White A, Luettgen J. Inhibitory effect of apixaban compared with rivaroxaban and dabigatran on thrombin generation assay. Hospital Practice (1995). 41: 19-25. PMID 23466964 DOI: 10.3810/hp.2013.02.1009  0.041
2021 Benmassaoud A, Bessissow T, Wong P, Fallone CA, Barkun A, Afif W, Forbes N, Martel M, Geraci O, Chen YI. Novel Negative Pressure Protective Box in Upper Digestive Endoscopy: A Prospective Case Series. The American Journal of Gastroenterology. PMID 33734112 DOI: 10.14309/ajg.0000000000001221  0.041
2001 Lee J, Yew WW, Wong PC, Fu KH. Non-Hodgkin's pleural lymphoma in long-standing tuberculous pyothorax mimicking suppuration. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 5: 167-9. PMID 11724676 DOI: 10.1016/S1201-9712(01)90094-3  0.041
2010 Perrachione TK, Chiao JY, Wong PC. Asymmetric cultural effects on perceptual expertise underlie an own-race bias for voices. Cognition. 114: 42-55. PMID 19782970 DOI: 10.1016/J.Cognition.2009.08.012  0.041
2022 Ramji A, Doucette K, Cooper C, Minuk GY, Ma M, Wong A, Wong D, Tam E, Conway B, Truong D, Wong P, Barrett L, Ko HH, Haylock-Jacobs S, Patel N, et al. Nationwide retrospective study of hepatitis B virological response and liver stiffness improvement in 465 patients on nucleos(t)ide analogue. World Journal of Gastroenterology. 28: 4390-4398. PMID 36159017 DOI: 10.3748/wjg.v28.i31.4390  0.041
2023 Wong P, Masucci L, Florescu M, Plourde ME, Panet-Raymond V, Pavic M, Owen S, Masson-Coté L, Ménard C, Routy B, Tehfe M, Nelson K, Guilbert F, Boucher O, Keshavarzi S, et al. Phase II multicenter trial combining nivolumab and radiosurgery for NSCLC and RCC brain metastases. Neuro-Oncology Advances. 5: vdad018. PMID 37025758 DOI: 10.1093/noajnl/vdad018  0.041
2011 Ettlinger M, Margulis EH, Wong PC. Implicit memory in music and language. Frontiers in Psychology. 2: 211. PMID 21927608 DOI: 10.3389/Fpsyg.2011.00211  0.041
2014 Sabati AA, Wong PC, Randolph L, Pruetz JD. Absent aortic valve associated with double outlet right ventricle and aortopulmonary window: physiologic implications of a rare malformation in both the fetus and neonate. Congenital Heart Disease. 9: E98-E104. PMID 23701730 DOI: 10.1111/chd.12089  0.04
2009 Qiao JX, King SR, He K, Wong PC, Rendina AR, Luettgen JM, Xin B, Knabb RM, Wexler RR, Lam PY. Highly efficacious factor Xa inhibitors containing alpha-substituted phenylcycloalkyl P4 moieties. Bioorganic & Medicinal Chemistry Letters. 19: 462-8. PMID 19046881 DOI: 10.1016/j.bmcl.2008.11.049  0.04
2021 Chmura S, Winter KA, Robinson C, Pisansky TM, Borges V, Al-Hallaq H, Matuszak M, Park SS, Yi S, Hasan Y, Bazan J, Wong P, Yoon HA, Horton J, Gan G, et al. Evaluation of Safety of Stereotactic Body Radiotherapy for the Treatment of Patients With Multiple Metastases: Findings From the NRG-BR001 Phase 1 Trial. Jama Oncology. PMID 33885704 DOI: 10.1001/jamaoncol.2021.0687  0.04
2007 Guo C, Haider HKh, Shim WS, Tan RS, Ye L, Jiang S, Law PK, Wong P, Sim EK. Myoblast-based cardiac repair: xenomyoblast versus allomyoblast transplantation. The Journal of Thoracic and Cardiovascular Surgery. 134: 1332-9. PMID 17976470 DOI: 10.1016/j.jtcvs.2007.07.025  0.04
2014 Sieber CM, Lee W, Wong P, Münsterkötter M, Mewes HW, Schmeitzl C, Varga E, Berthiller F, Adam G, Güldener U. The Fusarium graminearum genome reveals more secondary metabolite gene clusters and hints of horizontal gene transfer. Plos One. 9: e110311. PMID 25333987 DOI: 10.1371/journal.pone.0110311  0.04
2012 Wong P, Hsieh F, Pham R, James CA. Critical review of p38 MAP kinase inhibitors: a bioanalytical perspective. Bioanalysis. 4: 89-93. PMID 22191596 DOI: 10.4155/bio.11.290  0.04
2021 Bavoux M, Kamio Y, Vigneux-Foley E, Lafontaine J, Najyb O, Refet-Mollof E, Carrier JF, Gervais T, Wong P. X-Ray on chip: quantifying therapeutic synergies between radiotherapy and anticancer drugs using soft tissue sarcoma tumor spheroids. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 33516789 DOI: 10.1016/j.radonc.2021.01.018  0.04
2011 Theis FJ, Latif N, Wong P, Frishman D. Complex principal component and correlation structure of 16 yeast genomic variables. Molecular Biology and Evolution. 28: 2501-12. PMID 21444651 DOI: 10.1093/molbev/msr077  0.04
2006 Pinto DJ, Galemmo RA, Quan ML, Orwat MJ, Clark C, Li R, Wells B, Woerner F, Alexander RS, Rossi KA, Smallwood A, Wong PC, Luettgen JM, Rendina AR, Knabb RM, et al. Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties. Bioorganic & Medicinal Chemistry Letters. 16: 5584-9. PMID 16963264 DOI: 10.1016/j.bmcl.2006.08.027  0.04
2019 Merchante N, Saroli Palumbo C, Mazzola G, Pineda JA, Téllez F, Rivero-Juárez A, Ríos-Villegas MJ, Maurice JB, Westbrook RH, Judge R, Guaraldi G, Schepis F, Perazzo H, Rockstroh J, Boesecke C, ... ... Wong P, et al. Prediction of Esophageal Varices by Liver Stiffness and Platelets in Persons with HIV infection and Compensated Advanced Chronic Liver Disease. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31813962 DOI: 10.1093/Cid/Ciz1181  0.04
2012 Wong PC, Morgan-Short K, Ettlinger M, Zheng J. Linking neurogenetics and individual differences in language learning: the dopamine hypothesis. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 48: 1091-102. PMID 22565204 DOI: 10.1016/J.Cortex.2012.03.017  0.04
2015 Hill GD, Frommelt PC, Stelter J, Campbell MJ, Cohen MS, Kharouf R, Lai WW, Levine JC, Lu JC, Menon SC, Slesnick TC, Wong PC, Saudek DE. Impact of initial norwood shunt type on right ventricular deformation: the single ventricle reconstruction trial. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 28: 517-21. PMID 25690998 DOI: 10.1016/j.echo.2015.01.018  0.04
2023 Hass A, Qatomah A, Deschenes M, Wong P. Importance of gender differences in body composition for liver transplantation and the 'Sarco-Model' study. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 37563939 DOI: 10.1111/liv.15693  0.04
2011 He K, Luettgen JM, Zhang D, He B, Grace JE, Xin B, Pinto DJ, Wong PC, Knabb RM, Lam PY, Wexler RR, Grossman SJ. Preclinical pharmacokinetics and pharmacodynamics of apixaban, a potent and selective factor Xa inhibitor. European Journal of Drug Metabolism and Pharmacokinetics. 36: 129-39. PMID 21461793 DOI: 10.1007/s13318-011-0037-x  0.039
2009 Wong PC, Perrachione TK, Gunasekera G, Chandrasekaran B. Communication disorders in speakers of tone languages: etiological bases and clinical considerations. Seminars in Speech and Language. 30: 162-73. PMID 19711234 DOI: 10.1055/S-0029-1225953  0.039
2017 Bhat M, Rollet-Kurhajec KC, Bhat A, Farag A, Deschenes M, Wong P, Ghali P, Sebastiani G. Incidence and Predictors of Advanced Liver Fibrosis by a Validated Serum Biomarker in Liver Transplant Recipients. Canadian Journal of Gastroenterology & Hepatology. 2017: 4381864. PMID 28409147 DOI: 10.1155/2017/4381864  0.039
2014 Yuan J, Zhou J, Dong Z, Tandon S, Kuk D, Panageas KS, Wong P, Wu X, Naidoo J, Page DB, Wolchok JD, Hodi FS. Pretreatment serum VEGF is associated with clinical response and overall survival in advanced melanoma patients treated with ipilimumab. Cancer Immunology Research. 2: 127-32. PMID 24778276 DOI: 10.1158/2326-6066.CIR-13-0163  0.039
2004 Wong PC, Parsons LM, Martinez M, Diehl RL. The role of the insular cortex in pitch pattern perception: the effect of linguistic contexts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9153-60. PMID 15483134 DOI: 10.1523/Jneurosci.2225-04.2004  0.039
2014 Rosenstein BS, West CM, Bentzen SM, Alsner J, Andreassen CN, Azria D, Barnett GC, Baumann M, Burnet N, Chang-Claude J, Chuang EY, Coles CE, Dekker A, De Ruyck K, De Ruysscher D, ... ... Wong P, et al. Radiogenomics: radiobiology enters the era of big data and team science. International Journal of Radiation Oncology, Biology, Physics. 89: 709-13. PMID 24969789 DOI: 10.1016/J.Ijrobp.2014.03.009  0.039
2002 Loganath A, Peh KL, Wong PC. Evidence for the biosynthesis of DHEA from cholesterol by first-trimester human placental tissue: source of androgens. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 34: 116-20. PMID 11972299 DOI: 10.1055/s-2002-23193  0.039
2015 Glunz PW, Cheng X, Cheney DL, Weigelt CA, Wei A, Luettgen JM, Wong PC, Wexler RR, Priestley ES. Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors. Bioorganic & Medicinal Chemistry Letters. 25: 2169-73. PMID 25881820 DOI: 10.1016/j.bmcl.2015.03.062  0.039
2010 Chandrasekaran B, Sampath PD, Wong PC. Individual variability in cue-weighting and lexical tone learning. The Journal of the Acoustical Society of America. 128: 456-65. PMID 20649239 DOI: 10.1121/1.3445785  0.039
2015 Wong PC, Heng PW, Chan LW. Determination of solid state characteristics of spray-congealed Ibuprofen solid lipid microparticles and their impact on sustaining drug release. Molecular Pharmaceutics. 12: 1592-604. PMID 25849584 DOI: 10.1021/acs.molpharmaceut.5b00015  0.039
2011 Perrachione TK, Lee J, Ha LY, Wong PC. Learning a novel phonological contrast depends on interactions between individual differences and training paradigm design. The Journal of the Acoustical Society of America. 130: 461-72. PMID 21786912 DOI: 10.1121/1.3593366  0.038
2013 Wang TC, Qiao JX, Clark CG, Jua J, Price LA, Wu Q, Chang M, Zheng J, Huang CS, Everlof G, Schumacher WA, Wong PC, Seiffert DA, Stewart AB, Bostwick JS, et al. Discovery of diarylurea P2Y(1) antagonists with improved aqueous solubility. Bioorganic & Medicinal Chemistry Letters. 23: 3239-43. PMID 23602442 DOI: 10.1016/j.bmcl.2013.03.125  0.038
2021 Farag MS, Fung S, Tam E, Doucette K, Wong A, Ramji A, Conway B, Cooper C, Tsoi K, Wong P, Sebastiani G, Brahmania M, Haylock-Jacobs S, Coffin CS, Hansen BE, et al. Effectiveness and Renal Safety of Tenofovir Alafenamide Fumarate among Chronic Hepatitis B Patients: Real-World Study. Journal of Viral Hepatitis. PMID 33749086 DOI: 10.1111/jvh.13500  0.038
2022 Smith MK, Chow J, Huang R, Omar M, Ebadi M, Wong P, Huard G, Yoshida EM, Peretz D, Brahmania M, Montano-Loza AJ, Bhanji RA. COVID-19 infection in liver transplant recipients: Clinical features and outcomes from a Canadian multicentre cohort. Canadian Liver Journal. 5: 507-512. PMID 38144413 DOI: 10.3138/canlivj-2022-0015  0.038
2018 Benmassaoud A, Ghali P, Cox J, Wong P, Szabo J, Deschenes M, Osikowicz M, Lebouche B, Klein MB, Sebastiani G. Screening for nonalcoholic steatohepatitis by using cytokeratin 18 and transient elastography in HIV mono-infection. Plos One. 13: e0191985. PMID 29381754 DOI: 10.1371/Journal.Pone.0191985  0.038
2016 Zhao X, Wong P. Managing Sleep Disturbances in Cirrhosis. Scientifica. 2016: 6576812. PMID 27242950 DOI: 10.1155/2016/6576812  0.038
2016 Bahig H, Simard D, Létourneau L, Wong P, Roberge D, Filion E, Donath D, Sahgal A, Masucci L. A Study of Pseudoprogression After Spine Stereotactic Body Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics. 96: 848-856. PMID 27788956 DOI: 10.1016/J.Ijrobp.2016.07.034  0.038
2002 Wong PC, Crain EJ, Watson CA, Zaspel AM, Wright MR, Lam PY, Pinto DJ, Wexler RR, Knabb RM. Nonpeptide factor Xa inhibitors III: effects of DPC423, an orally-active pyrazole antithrombotic agent, on arterial thrombosis in rabbits. The Journal of Pharmacology and Experimental Therapeutics. 303: 993-1000. PMID 12438519 DOI: 10.1124/Jpet.102.040089  0.038
2012 Loh SF, Wong PC, Jiang B, Yeo GH, Tan AS, Prasath EB, Mathew J, Chan ML, Tan WC, Choolani M, Yap CH, Chong SS. Preimplantation genetic diagnosis of chromosome translocations by analysis of polymorphic short tandem repeats. Singapore Medical Journal. 53: 648-54. PMID 23112015  0.038
2014 Du G, Wong PC, Chang Q, Li Z. High-throughput microwell plate for cell research. Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University. 34: 5-7. PMID 24463107  0.038
2014 Chan RW, Jiang P, Peng X, Tam LS, Liao GJ, Li EK, Wong PC, Sun H, Chan KC, Chiu RW, Lo YM. Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing. Proceedings of the National Academy of Sciences of the United States of America. 111: E5302-11. PMID 25427797 DOI: 10.1073/pnas.1421126111  0.038
2015 Wong PC, Heng PW, Chan LW. Spray congealing as a microencapsulation technique to develop modified-release ibuprofen solid lipid microparticles: the effect of matrix type, polymeric additives and drug-matrix miscibility. Journal of Microencapsulation. 1-12. PMID 26242841 DOI: 10.3109/02652048.2015.1073387  0.037
2011 Wong PC, Qiao J, Ho C, Ramaraju GA, Wiweko B, Takehara Y, Nadkarni PV, Cheng LC, Chen HF, Suwajanakorn S, Vuong TN. Current opinion on use of luteinizing hormone supplementation in assisted reproduction therapy: an Asian perspective. Reproductive Biomedicine Online. 23: 81-90. PMID 21550853 DOI: 10.1016/j.rbmo.2011.03.023  0.037
2006 Quan ML, Han Q, Fevig JM, Lam PY, Bai S, Knabb RM, Luettgen JM, Wong PC, Wexler RR. Aminobenzisoxazoles with biaryl P4 moieties as potent, selective, and orally bioavailable factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 1795-8. PMID 16434195 DOI: 10.1016/j.bmcl.2006.01.010  0.037
2019 Coffin CS, Ramji A, Cooper CL, Miles D, Doucette KE, Wong P, Tam E, Wong DK, Wong A, Ukabam S, Bailey RJ, Tsoi K, Conway B, Barrett L, Michalak TI, et al. Epidemiologic and clinical features of chronic hepatitis B virus infection in 8 Canadian provinces: a descriptive study by the Canadian HBV Network. Cmaj Open. 7: E610-E617. PMID 31641059 DOI: 10.9778/cmajo.20190103  0.037
2008 Wong PC, Chia MY, Tsou IY, Wansaicheong GK, Tan B, Wang JC, Tan J, Kim CG, Boh G, Lim D. Effects of a 12-week exercise training programme on aerobic fitness, body composition, blood lipids and C-reactive protein in adolescents with obesity. Annals of the Academy of Medicine, Singapore. 37: 286-93. PMID 18461212  0.037
2014 Miao Q, Shim W, Tee N, Lim SY, Chung YY, Ja KP, Ooi TH, Tan G, Kong G, Wei H, Lim CH, Sin YK, Wong P. iPSC-derived human mesenchymal stem cells improve myocardial strain of infarcted myocardium. Journal of Cellular and Molecular Medicine. 18: 1644-54. PMID 24974908 DOI: 10.1111/jcmm.12351  0.037
2015 Li G, Xie ZZ, Chua JM, Wong PC, Bian J. Hydrogen sulfide protects testicular germ cells against heat-induced injury. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 46: 165-71. PMID 25446250 DOI: 10.1016/j.niox.2014.10.005  0.037
2015 Sebastiani G, Alshaalan R, Wong P, Rubino M, Salman A, Metrakos P, Deschenes M, Ghali P. Prognostic Value of Non-Invasive Fibrosis and Steatosis Tools, Hepatic Venous Pressure Gradient (HVPG) and Histology in Nonalcoholic Steatohepatitis. Plos One. 10: e0128774. PMID 26083565 DOI: 10.1371/journal.pone.0128774  0.037
2011 Chandrasekaran B, Chan AH, Wong PC. Neural processing of what and who information in speech. Journal of Cognitive Neuroscience. 23: 2690-700. PMID 21268667 DOI: 10.1162/Jocn.2011.21631  0.037
2008 Wong PC, Watson CA, Crain EJ. Arterial antithrombotic and bleeding time effects of apixaban, a direct factor Xa inhibitor, in combination with antiplatelet therapy in rabbits. Journal of Thrombosis and Haemostasis : Jth. 6: 1736-41. PMID 18647224 DOI: 10.1111/j.1538-7836.2008.03092.x  0.036
2009 Antonov AV, Dietmann S, Wong P, Lutter D, Mewes HW. GeneSet2miRNA: Finding the signature of cooperative miRNA activities in the gene lists Nucleic Acids Research. 37. PMID 19420064 DOI: 10.1093/nar/gkp313  0.036
2014 Frommelt PC, Gerstenberger E, Cnota JF, Cohen MS, Gorentz J, Hill KD, John JB, Levine JC, Lu J, Mahle WT, McCandless RT, Mertens L, Pearson GD, Spencer C, Thacker D, ... ... Wong PC, et al. Impact of initial shunt type on cardiac size and function in children with single right ventricle anomalies before the Fontan procedure: the single ventricle reconstruction extension trial. Journal of the American College of Cardiology. 64: 2026-35. PMID 25440099 DOI: 10.1016/j.jacc.2014.08.033  0.036
2009 Wong PC, Roy AK, Margulis EH. Bimusicalism: The Implicit Dual Enculturation of Cognitive and Affective Systems. Music Perception. 27: 81-88. PMID 20657798 DOI: 10.1525/Mp.2009.27.2.81  0.036
2018 Bulluck H, Chan M, Bryant J, Chai P, Chawla A, Chua T, Chung YC, Gao F, Ho HH, Ho AFW, Hoe AJ, Syed Saqib I, Lee R, Han LS, Liew BW, ... ... Wong P, et al. Platelet Inhibition to Target Reperfusion Injury (The PITRI trial): Rationale and Study Design. Clinical Cardiology. PMID 30421441 DOI: 10.1002/Clc.23110  0.036
2004 Aradhana R, Rajashekhar G, Roy AC, Annapoorna V, Dramusic V, Choolani M, Wong PC. Estrogen receptor alpha gene PvuII polymorphism and polycystic ovary syndrome. Annals of the Academy of Medicine, Singapore. 33: S89-90. PMID 15651230  0.036
2015 Foin N, Lee R, Mattesini A, Caiazzo G, Fabris E, Kilic D, Chan JN, Huang Y, Venkatraman SS, Di Mario C, Wong P, Nef H. Bioabsorbable vascular scaffold overexpansion: insights from in vitro post-expansion experiments. Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. 11. PMID 26151954 DOI: 10.4244/EIJY15M07_02  0.036
2007 Wong PC. Changes in speech production in an early deafened adult with a cochlear implant. International Journal of Language & Communication Disorders / Royal College of Speech & Language Therapists. 42: 387-405. PMID 17613096 DOI: 10.1080/13682820600988868  0.035
2008 Wong PC, Uppunda AK, Parrish TB, Dhar S. Cortical mechanisms of speech perception in noise. Journal of Speech, Language, and Hearing Research : Jslhr. 51: 1026-41. PMID 18658069 DOI: 10.1044/1092-4388(2008/075)  0.035
2017 Wong P, Kassam Z, Springer AN, Gladdy R, Chung P, Ringash J, Catton C. Long-Term Quality of Life of Retroperitoneal Sarcoma Patients Treated with Pre-Operative Radiotherapy and Surgery. Cureus. 9: e1764. PMID 29234568 DOI: 10.7759/Cureus.1764  0.035
2015 Wong P, Hui A, Su J, Yue S, Haibe-Kains B, Gokgoz N, Xu W, Bruce J, Williams J, Catton C, Wunder JS, Andrulis IL, Gladdy R, Dickson B, O'Sullivan B, et al. Prognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas. Oncotarget. PMID 25970788 DOI: 10.18632/Oncotarget.3926  0.035
2014 Foin N, Gutiérrez-Chico JL, Nakatani S, Torii R, Bourantas CV, Sen S, Nijjer S, Petraco R, Kousera C, Ghione M, Onuma Y, Garcia-Garcia HM, Francis DP, Wong P, Di Mario C, et al. Incomplete stent apposition causes high shear flow disturbances and delay in neointimal coverage as a function of strut to wall detachment distance: implications for the management of incomplete stent apposition. Circulation. Cardiovascular Interventions. 7: 180-9. PMID 24642998 DOI: 10.1161/CIRCINTERVENTIONS.113.000931  0.035
2014 Skoe E, Chandrasekaran B, Spitzer ER, Wong PC, Kraus N. Human brainstem plasticity: the interaction of stimulus probability and auditory learning. Neurobiology of Learning and Memory. 109: 82-93. PMID 24291573 DOI: 10.1016/J.Nlm.2013.11.011  0.035
2013 Shim W, Mehta A, Wong P, Chua T, Koh TH. Critical path in cardiac stem cell therapy: an update on cell delivery. Cytotherapy. 15: 399-415. PMID 23294824 DOI: 10.1016/j.jcyt.2012.11.003  0.035
2012 Wong PC, Chan AH, Margulis EH. Effects of mono- and bicultural experiences on auditory perception. Annals of the New York Academy of Sciences. 1252: 158-62. PMID 22524354 DOI: 10.1111/J.1749-6632.2012.06407.X  0.035
2008 Mattar CN, Chong YS, Su LL, Agarwal AA, Wong PC, Choolani M. Care of women in menopause: sexual function, dysfunction and therapeutic modalities. Annals of the Academy of Medicine, Singapore. 37: 215-23. PMID 18392301  0.035
2001 Fevig JM, Pinto DJ, Han Q, Quan ML, Pruitt JR, Jacobson IC, Galemmo RA, Wang S, Orwat MJ, Bostrom LL, Knabb RM, Wong PC, Lam PYS, Wexler RR. Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core. Bioorganic & Medicinal Chemistry Letters. 11: 641-5. PMID 11266160 DOI: 10.1016/S0960-894X(01)00029-4  0.035
2012 Al-Busafi SA, Ghali P, Wong P, Deschenes M. Endoscopic management of portal hypertension. International Journal of Hepatology. 2012: 747095. PMID 22830037 DOI: 10.1155/2012/747095  0.034
2011 Wong PC, Ettlinger M. Predictors of spoken language learning. Journal of Communication Disorders. 44: 564-7. PMID 21601868 DOI: 10.1016/J.Jcomdis.2011.04.003  0.034
2022 Osiowy C, Swidinsky K, Haylock-Jacobs S, Sadler MD, Fung S, Wong D, Minuk GY, Doucette KE, Wong P, Tam E, Cooper C, Ramji A, Ma M, Nudo C, Tsoi K, et al. Molecular epidemiology and clinical characteristics of hepatitis D virus infection in Canada. Jhep Reports : Innovation in Hepatology. 4: 100461. PMID 35360523 DOI: 10.1016/j.jhepr.2022.100461  0.034
2013 Lee TY, Tong X, Shen HW, Wong PC, Hagos S, Leung LR. Feature tracking and visualization of the Madden-Julian oscillation in climate simulation. Ieee Computer Graphics and Applications. 33: 29-37. PMID 24808057 DOI: 10.1109/Mcg.2013.36  0.034
2006 Lam B, Wong MP, Fung SL, Lam DC, Wong PC, Mok TY, Lam FM, Ip MS, Ooi CG, Lam WK. The clinical value of autofluorescence bronchoscopy for the diagnosis of lung cancer. The European Respiratory Journal. 28: 915-9. PMID 16870657 DOI: 10.1183/09031936.06.00131405  0.034
2008 Skaggs DL, Bushman G, Grunander T, Wong PC, Sankar WN, Tolo VT. Shortening of growing-rod spinal instrumentation reverses cardiac failure in child with Marfan syndrome and scoliosis. A case report. The Journal of Bone and Joint Surgery. American Volume. 90: 2745-50. PMID 19047721 DOI: 10.2106/JBJS.H.00263  0.033
2019 Bahig H, Aubin F, Stagg J, Gologan O, Ballivy O, Bissada E, Nguyen-Tan FP, Soulières D, Guertin L, Filion E, Christopoulos A, Lambert L, Tehfe M, Ayad T, Charpentier D, ... ... Wong P, et al. Phase I/II trial of Durvalumab plus Tremelimumab and stereotactic body radiotherapy for metastatic head and neck carcinoma. Bmc Cancer. 19: 68. PMID 30642290 DOI: 10.1186/S12885-019-5266-4  0.033
2022 Barry A, Mina DS, Langelier DM, Wong P, Anne Koch C. Supporting an Athlete With Breast Cancer: A Case Report. Journal of Patient Experience. 9: 23743735221077539. PMID 35155753 DOI: 10.1177/23743735221077539  0.033
2019 Kosik I, Brackstone M, Kornecki A, Chamson-Reig A, Wong P, Araghi MH, Carson JJ. Intraoperative photoacoustic screening of breast cancer: a new perspective on malignancy visualization and surgical guidance. Journal of Biomedical Optics. 24: 1-12. PMID 31111698 DOI: 10.1117/1.JBO.24.5.056002  0.033
2016 Foin N, Lee R, Bourantas C, Mattesini A, Soh N, Lim JE, Torii R, Ng J, Liang LH, Caiazzo G, Fabris E, Kilic D, Onuma Y, Low AF, Nijjer S, ... ... Wong P, et al. Bioresorbable vascular scaffold radial expansion and conformation compared to a metallic platform: insights from in vitro expansion in a coronary artery lesion model. Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. 12: 834-844. PMID 27639735 DOI: 10.4244/EIJV12I7A138  0.033
2016 Ng J, Foin N, Ang HY, Fam JM, Sen S, Nijjer S, Petraco R, Di Mario C, Davies J, Wong P. Over-expansion capacity and stent design model: An update with contemporary DES platforms. International Journal of Cardiology. 221: 171-179. PMID 27400317 DOI: 10.1016/j.ijcard.2016.06.097  0.033
1998 Fevig JM, Cacciola J, Alexander RS, Knabb RM, Lam GN, Wong PC, Wexler RR. Preparation of meta-amidino-N,N-disubstituted anilines as potent inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 8: 3143-8. PMID 9873692  0.032
2015 Arslan H, Peterman BR, Wong PC, Bhattacharjee S. Remaining capacity of the suction pile due to seabed trenching Proceedings of the International Offshore and Polar Engineering Conference. 2015: 924-931.  0.032
2009 Wong PC, Leung LR, Lu N, Scott MJ, Mackey P, Foote H, Correia J, Taylor ZT, Xu J, Unwin SD, Sanfilippo A. Designing a collaborative visual analytics tool for social and technological change prediction. Ieee Computer Graphics and Applications. 29: 58-68. PMID 19927437 DOI: 10.1109/Mcg.2009.92  0.032
2017 Myu Mai Ja KP, Lim KP, Chen A, Ting S, Li SQ, Tee N, Ramachandra C, Mehta A, Wong P, Oh S, Shim W. Construction of a Vascularized Hydrogel for Cardiac Tissue Formation in a Porcine Model. Journal of Tissue Engineering and Regenerative Medicine. PMID 29266858 DOI: 10.1002/term.2634  0.032
1998 Woo MS, MacLaughlin EF, Horn MV, Wong PC, Rowland JM, Barr ML, Starnes VA. Living donor lobar lung transplantation: the pediatric experience. Pediatric Transplantation. 2: 185-90. PMID 10084740  0.032
2014 Bhat M, Ghali P, Deschenes M, Wong P. Prevention and Management of Chronic Hepatitis B. International Journal of Preventive Medicine. 5: S200-S207. PMID 26622990  0.032
2006 Fevig JM, Cacciola J, Buriak J, Rossi KA, Knabb RM, Luettgen JM, Wong PC, Bai SA, Wexler RR, Lam PY. Preparation of 1-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective and bioavailable inhibitors of coagulation factor Xa. Bioorganic & Medicinal Chemistry Letters. 16: 3755-60. PMID 16682200 DOI: 10.1002/CHIN.200643175  0.032
2010 Chung CH, Siu AY, Po LL, Lam CY, Wong PC. Comparing the effectiveness of video self-instruction versus traditional classroom instruction targeted at cardiopulmonary resuscitation skills for laypersons: a prospective randomised controlled trial. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 16: 165-70. PMID 20519751  0.031
2007 Lee AM, Wong JG, McAlonan GM, Cheung V, Cheung C, Sham PC, Chu CM, Wong PC, Tsang KW, Chua SE. Stress and psychological distress among SARS survivors 1 year after the outbreak. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 52: 233-40. PMID 17500304 DOI: 10.1177/070674370705200405  0.031
2021 Zhao X, Huang R, Wong P, Fiset PO, Deschênes M. Renal tubular injury in hyperbilirubinemia: Bile cast nephropathy. Canadian Liver Journal. 4: 332-337. PMID 35992254 DOI: 10.3138/canlivj-2020-0031  0.031
2005 Ho PL, Chau PH, Yip PS, Ooi GC, Khong PL, Ho JC, Wong PC, Ko C, Yan C, Tsang KW. A prediction rule for clinical diagnosis of severe acute respiratory syndrome. The European Respiratory Journal. 26: 474-9. PMID 16135731 DOI: 10.1183/09031936.05.1076704  0.031
2013 Jiang J, James CA, Wong P. Determination of rosiglitazone and 5-hydroxy rosiglitazone in rat plasma using LC-HRMS by direct and indirect quantitative analysis: a new approach for metabolite quantification. Bioanalysis. 5: 1873-81. PMID 23905861 DOI: 10.4155/bio.13.140  0.031
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