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Karen A. O'Connell, Ph.D. - Publications

Affiliations: 
2011 Johns Hopkins University, Baltimore, MD 
Area:
Virology Biology, Immunology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Buckheit RW, Allen TG, Alme A, Salgado M, O'Connell KA, Huculak S, Falade-Nwulia O, Williams TM, Gallant JE, Siliciano RF, Blankson JN. Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs. Nature Communications. 3: 716. PMID 22395607 DOI: 10.1038/Ncomms1697  0.73
2012 O'Connell KA, Skevington SM. An international quality of life instrument to assess wellbeing in adults who are HIV-positive: A short form of the WHOQOL-HIV (31 items) Aids and Behavior. 16: 452-460. PMID 21181253 DOI: 10.1007/s10461-010-9863-0  0.454
2011 Salgado M, Rabi SA, O'Connell KA, Buckheit RW, Bailey JR, Chaudhry AA, Breaud AR, Marzinke MA, Clarke W, Margolick JB, Siliciano RF, Blankson JN. Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy. Retrovirology. 8: 97. PMID 22141397 DOI: 10.1186/1742-4690-8-97  0.837
2011 O'Connell KA, Rabi SA, Siliciano RF, Blankson JN. CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors. Proceedings of the National Academy of Sciences of the United States of America. 108: E689-98. PMID 21873218 DOI: 10.1073/Pnas.1108866108  0.743
2011 O'Connell KA, Hegarty RW, Siliciano RF, Blankson JN. Viral suppression of multiple escape mutants by de novo CD8(+) T cell responses in a human immunodeficiency virus-1 infected elite suppressor. Retrovirology. 8: 63. PMID 21812985 DOI: 10.1186/1742-4690-8-63  0.732
2011 Spivak AM, Salgado M, Rabi SA, O'Connell KA, Blankson JN. Circulating monocytes are not a major reservoir of HIV-1 in elite suppressors. Journal of Virology. 85: 10399-403. PMID 21795348 DOI: 10.1128/Jvi.05409-11  0.716
2011 Gaillard S, Dinoso JB, Marsh JA, DeZern AE, O'Connell KA, Spivak AM, Alwood K, Durand CM, Ambinder RF, Blankson JN. Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 51: 195-8. PMID 21550842 DOI: 10.1016/J.Jcv.2011.04.002  0.816
2011 Rabi SA, O'Connell KA, Nikolaeva D, Bailey JR, Jilek BL, Shen L, Page KR, Siliciano RF, Blankson JN. Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. Journal of Virology. 85: 979-86. PMID 21068257 DOI: 10.1128/Jvi.01721-10  0.788
2010 Salgado M, Brennan TP, O'Connell KA, Bailey JR, Ray SC, Siliciano RF, Blankson JN. Evolution of the HIV-1 nef gene in HLA-B*57 positive elite suppressors. Retrovirology. 7: 94. PMID 21059238 DOI: 10.1186/1742-4690-7-94  0.769
2010 O'Connell KA, Pelz RK, Dinoso JB, Dunlop E, Paik-Tesch J, Williams TM, Blankson JN. Prolonged control of an HIV type 1 escape variant following treatment interruption in an HLA-B*27-positive patient. Aids Research and Human Retroviruses. 26: 1307-11. PMID 20854198 DOI: 10.1089/Aid.2010.0135  0.815
2010 Durand CM, O'Connell KA, Apuzzo LG, Langan SJ, Imteyaz H, Ahonkhai AA, Ceccato CM, Williams TM, Margolick JB, Blankson JN. HIV-1 Gag evolution in recently infected human leukocyte antigen-B*57 patients with low-level viremia. Aids (London, England). 24: 2405-8. PMID 20671542 DOI: 10.1097/Qad.0B013E32833D8A38  0.44
2010 O'Connell KA, Brennan TP, Bailey JR, Ray SC, Siliciano RF, Blankson JN. Control of HIV-1 in elite suppressors despite ongoing replication and evolution in plasma virus. Journal of Virology. 84: 7018-28. PMID 20444904 DOI: 10.1128/Jvi.00548-10  0.774
2010 Spivak AM, Brennan TP, O'Connell KA, Sydnor E, Williams TM, Siliciano RF, Gallant JE, Blankson JN. A case of seronegative HIV-1 infection. The Journal of Infectious Diseases. 201: 341-5. PMID 20039801 DOI: 10.1086/649822  0.764
2010 Sedaghat AR, Rastegar DA, O'Connell KA, Dinoso JB, Wilke CO, Blankson JN. Reply to torre Clinical Infectious Diseases. 50: 1425-1426. DOI: 10.1086/652285  0.696
2009 O'Connell KA, Xu J, Durbin AP, Apuzzo LG, Imteyaz H, Williams TM, Ray SC, Margolick JB, Siliciano RF, Blankson JN. HIV-1 evolution following transmission to an HLA-B*5801-positive patient. The Journal of Infectious Diseases. 200: 1820-4. PMID 19909081 DOI: 10.1086/648377  0.696
2009 Sedaghat AR, Rastegar DA, O'Connell KA, Dinoso JB, Wilke CO, Blankson JN. T cell dynamics and the response to HAART in a cohort of HIV-1-infected elite suppressors. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 49: 1763-6. PMID 19857162 DOI: 10.1086/648081  0.841
2009 O'Connell KA, Bailey JR, Blankson JN. Elucidating the elite: mechanisms of control in HIV-1 infection. Trends in Pharmacological Sciences. 30: 631-7. PMID 19837464 DOI: 10.1016/J.Tips.2009.09.005  0.78
2009 Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. The Journal of Clinical Investigation. 119: 3473-86. PMID 19805909 DOI: 10.1172/Jci39199  0.768
2009 O'Connell KA, Han Y, Williams TM, Siliciano RF, Blankson JN. Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro. Journal of Virology. 83: 5028-34. PMID 19211742 DOI: 10.1128/Jvi.02551-08  0.808
2009 Bailey JR, Brennan TP, O'Connell KA, Siliciano RF, Blankson JN. Evidence of CD8+ T-cell-mediated selective pressure on human immunodeficiency virus type 1 nef in HLA-B*57+ elite suppressors. Journal of Virology. 83: 88-97. PMID 18945771 DOI: 10.1128/Jvi.01958-08  0.787
2008 O'Connell K, Siliciano RF. Immune alteration fends off AIDS. Nature Medicine. 14: 1016-8. PMID 18841135 DOI: 10.1038/Nm1008-1016  0.637
2008 Han Y, Lin YB, An W, Xu J, Yang HC, O'Connell K, Dordai D, Boeke JD, Siliciano JD, Siliciano RF. Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. Cell Host & Microbe. 4: 134-46. PMID 18692773 DOI: 10.1016/J.Chom.2008.06.008  0.791
2008 Bailey JR, O'Connell K, Yang HC, Han Y, Xu J, Jilek B, Williams TM, Ray SC, Siliciano RF, Blankson JN. Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor. Journal of Virology. 82: 7395-410. PMID 18495769 DOI: 10.1128/Jvi.00800-08  0.776
2003 Skevington SM, O'Connell KA. Measuring quality of life in HIV and AIDS: A review of the recent literature Psychology and Health. 18: 331-350. DOI: 10.1080/0887044031000084030  0.398
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