Charles J. Epstein, M.D. - Publications

University of California, San Francisco, San Francisco, CA 
Medical Genetics

170 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Epstein CJ, Kwok L, Smith S. The source of lactate dehydrogenase in preimplantation mouse embryos. Febs Letters. 13: 45-48. PMID 11945628 DOI: 10.1016/0014-5793(71)80660-9  0.317
2011 Motulsky A, Epstein CJ. 2010 Victor A. McKusick Leadership Award introduction and address. American Journal of Human Genetics. 88: 269-72. PMID 21516616 DOI: 10.1016/J.Ajhg.2011.01.012  0.457
2010 Kim A, Joseph S, Khan A, Epstein CJ, Sobel R, Huang TT. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radical Biology & Medicine. 48: 1501-12. PMID 20188820 DOI: 10.1016/J.Freeradbiomed.2010.02.028  0.326
2010 Ishihara K, Amano K, Takaki E, Shimohata A, Sago H, Epstein CJ, Yamakawa K. Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of Down syndrome. Cerebral Cortex (New York, N.Y. : 1991). 20: 1131-43. PMID 19710359 DOI: 10.1093/Cercor/Bhp176  0.374
2009 Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1212-20. PMID 19776219 DOI: 10.1093/Gerona/Glp132  0.317
2009 Ishihara K, Amano K, Takaki E, Ebrahim AS, Shimohata A, Shibazaki N, Inoue I, Takaki M, Ueda Y, Sago H, Epstein CJ, Yamakawa K. Increased lipid peroxidation in Down's syndrome mouse models. Journal of Neurochemistry. 110: 1965-76. PMID 19645748 DOI: 10.1111/J.1471-4159.2009.06294.X  0.312
2009 Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Overexpression of Mn superoxide dismutase does not increase life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1114-25. PMID 19633237 DOI: 10.1093/Gerona/Glp100  0.319
2009 Pérez VI, Van Remmen H, Bokov A, Epstein CJ, Vijg J, Richardson A. The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell. 8: 73-5. PMID 19077044 DOI: 10.1111/J.1474-9726.2008.00449.X  0.333
2009 Larosche I, Choumar A, Fromenty B, Lettéron P, Abbey-Toby A, Van Remmen H, Epstein CJ, Richardson A, Feldmann G, Pessayre D, Mansouri A. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates. Toxicology and Applied Pharmacology. 234: 326-38. PMID 19063909 DOI: 10.1016/J.Taap.2008.11.004  0.311
2008 Canzonetta C, Mulligan C, Deutsch S, Ruf S, O'Doherty A, Lyle R, Borel C, Lin-Marq N, Delom F, Groet J, Schnappauf F, De Vita S, Averill S, Priestley JV, Martin JE, ... ... Epstein CJ, et al. DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. American Journal of Human Genetics. 83: 388-400. PMID 18771760 DOI: 10.1016/J.Ajhg.2008.08.012  0.343
2008 Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Epstein CJ, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/Vir.0.2008/001255-0  0.31
2008 Han ES, Muller FL, Pérez VI, Qi W, Liang H, Xi L, Fu C, Doyle E, Hickey M, Cornell J, Epstein CJ, Roberts LJ, Van Remmen H, Richardson A. The in vivo gene expression signature of oxidative stress. Physiological Genomics. 34: 112-26. PMID 18445702 DOI: 10.1152/Physiolgenomics.00239.2007  0.321
2008 Cadet JL, Sheng P, All S, Rothman R, Carlson E, Epstein C. Rapid Communication: Attenuation of Methamphetamine‐Induced Neurotoxicity in Copper/Zinc Superoxide Dismutase Transgenic Mice Journal of Neurochemistry. 62: 380-383. PMID 7505315 DOI: 10.1046/J.1471-4159.1994.62010380.X  0.348
2007 Belichenko PV, Kleschevnikov AM, Salehi A, Epstein CJ, Mobley WC. Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships. The Journal of Comparative Neurology. 504: 329-45. PMID 17663443 DOI: 10.1002/Cne.21433  0.351
2006 Shukkur EA, Shimohata A, Akagi T, Yu W, Yamaguchi M, Murayama M, Chui D, Takeuchi T, Amano K, Subramhanya KH, Hashikawa T, Sago H, Epstein CJ, Takashima A, Yamakawa K. Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome. Human Molecular Genetics. 15: 2752-62. PMID 16891409 DOI: 10.1093/Hmg/Ddl211  0.34
2006 Erker L, Schubert R, Elchuri S, Huang TT, Tarin D, Mueller K, Zielen S, Epstein CJ, Wynshaw-Boris A. Effect of the reduction of superoxide dismutase 1 and 2 or treatment with alpha-tocopherol on tumorigenesis in Atm-deficient mice. Free Radical Biology & Medicine. 41: 590-600. PMID 16863992 DOI: 10.1016/J.Freeradbiomed.2006.04.032  0.324
2006 Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, Huang TT, Epstein CJ, Roberts LJ, Csete M, Faulkner JA, Van Remmen H. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radical Biology & Medicine. 40: 1993-2004. PMID 16716900 DOI: 10.1016/J.Freeradbiomed.2006.01.036  0.305
2006 Huang TT, Naeemuddin M, Elchuri S, Yamaguchi M, Kozy HM, Carlson EJ, Epstein CJ. Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Human Molecular Genetics. 15: 1187-94. PMID 16497723 DOI: 10.1093/Hmg/Ddl034  0.366
2006 Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mechanisms of Ageing and Development. 127: 298-306. PMID 16405961 DOI: 10.1016/J.Mad.2005.11.004  0.324
2006 Epstein CJ. Down Syndrome, Molecular Genetics of Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200300030  0.345
2005 Siarey RJ, Villar AJ, Epstein CJ, Galdzicki Z. Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome. Neuropharmacology. 49: 122-8. PMID 15992587 DOI: 10.1016/J.Neuropharm.2005.02.012  0.304
2005 Villar AJ, Belichenko PV, Gillespie AM, Kozy HM, Mobley WC, Epstein CJ. Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 79-90. PMID 15859352 DOI: 10.1007/S00335-004-2428-7  0.366
2005 Zhao Y, Chaiswing L, Oberley TD, Batinic-Haberle I, St Clair W, Epstein CJ, St Clair D. A mechanism-based antioxidant approach for the reduction of skin carcinogenesis. Cancer Research. 65: 1401-5. PMID 15735027 DOI: 10.1158/0008-5472.Can-04-3334  0.302
2005 Lynn S, Huang EJ, Elchuri S, Naeemuddin M, Nishinaka Y, Yodoi J, Ferriero DM, Epstein CJ, Huang TT. Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice. Free Radical Biology & Medicine. 38: 817-28. PMID 15721992 DOI: 10.1016/J.Freeradbiomed.2004.12.020  0.344
2005 Dauphinot L, Lyle R, Rivals I, Dang MT, Moldrich RX, Golfier G, Ettwiller L, Toyama K, Rossier J, Personnaz L, Antonarakis SE, Epstein CJ, Sinet PM, Potier MC. The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome. Human Molecular Genetics. 14: 373-84. PMID 15590701 DOI: 10.1093/Hmg/Ddi033  0.312
2005 Villar AJ, Kim J, De Blank P, Gillespie AM, Kozy HM, Ursell PC, Epstein CJ. Effects of genetic background on cardiovascular anomalies in the Ts16 mouse. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 131-9. PMID 15580624 DOI: 10.1002/Dvdy.20216  0.311
2005 Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, Epstein CJ, Huang TT. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene. 24: 367-80. PMID 15531919 DOI: 10.1038/Sj.Onc.1208207  0.331
2004 Olson LE, Roper RJ, Baxter LL, Carlson EJ, Epstein CJ, Reeves RH. Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 230: 581-9. PMID 15188443 DOI: 10.1002/Dvdy.20079  0.384
2004 Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radical Biology & Medicine. 36: 1625-34. PMID 15182862 DOI: 10.1016/J.Freeradbiomed.2004.03.016  0.349
2004 Amano K, Sago H, Uchikawa C, Suzuki T, Kotliarova SE, Nukina N, Epstein CJ, Yamakawa K. Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome. Human Molecular Genetics. 13: 1333-40. PMID 15138197 DOI: 10.1093/Hmg/Ddh154  0.364
2003 Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiological Genomics. 16: 29-37. PMID 14679299 DOI: 10.1152/Physiolgenomics.00122.2003  0.345
2003 Sutton VR, McAlister WH, Bertin TK, Kaffe S, Wang JC, Yano S, Shaffer LG, Lee B, Epstein CJ, Villar AJ. Skeletal defects in paternal uniparental disomy for chromosome 14 are re-capitulated in the mouse model (paternal uniparental disomy 12). Human Genetics. 113: 447-51. PMID 12938037 DOI: 10.1007/S00439-003-0981-X  0.357
2002 Zhao Y, Oberley TD, Chaiswing L, Lin SM, Epstein CJ, Huang TT, St Clair D. Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model. Oncogene. 21: 3836-46. PMID 12032821 DOI: 10.1038/Sj.Onc.1205477  0.356
2002 Huang TT, Raineri I, Eggerding F, Epstein CJ. Transgenic and mutant mice for oxygen free radical studies. Methods in Enzymology. 349: 191-213. PMID 11912909 DOI: 10.1016/S0076-6879(02)49335-4  0.311
2002 Richtsmeier JT, Zumwalt A, Carlson EJ, Epstein CJ, Reeves RH. Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome. American Journal of Medical Genetics. 107: 317-24. PMID 11840489 DOI: 10.1002/Ajmg.10175  0.399
2002 Asikainen TM, Huang TT, Taskinen E, Levonen AL, Carlson E, Lapatto R, Epstein CJ, Raivio KO. Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity. Free Radical Biology & Medicine. 32: 175-86. PMID 11796207 DOI: 10.1016/S0891-5849(01)00776-6  0.321
2002 Yang B, Bankir L, Gillespie A, Epstein CJ, Verkman AS. Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. The Journal of Biological Chemistry. 277: 10633-7. PMID 11792714 DOI: 10.1074/Jbc.M200207200  0.314
2001 Huang TT, Carlson EJ, Kozy HM, Mantha S, Goodman SI, Ursell PC, Epstein CJ. Genetic modification of prenatal lethality and dilated cardiomyopathy in Mn superoxide dismutase mutant mice. Free Radical Biology & Medicine. 31: 1101-10. PMID 11677043 DOI: 10.1016/S0891-5849(01)00694-3  0.359
2001 Raineri I, Carlson EJ, Gacayan R, Carra S, Oberley TD, Huang TT, Epstein CJ. Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility. Free Radical Biology & Medicine. 31: 1018-30. PMID 11595386 DOI: 10.1016/S0891-5849(01)00686-4  0.345
2001 Villar AJ, Carlson EJ, Gillespie AM, Ursell PC, Epstein CJ. Cardiomyopathy in mice with paternal uniparental disomy for chromosome 12. Genesis (New York, N.Y. : 2000). 30: 274-9. PMID 11536434 DOI: 10.1002/Gene.1074  0.349
2001 Van Remmen H, Williams MD, Guo Z, Estlack L, Yang H, Carlson EJ, Epstein CJ, Huang TT, Richardson A. Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1422-32. PMID 11514315 DOI: 10.1152/Ajpheart.2001.281.3.H1422  0.324
2001 Sha SH, Zajic G, Epstein CJ, Schacht J. Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss. Audiology & Neuro-Otology. 6: 117-23. PMID 11474137 DOI: 10.1159/000046818  0.338
2001 Guo Z, Van Remmen H, Yang H, Chen X, Mele J, Vijg J, Epstein CJ, Ho YS, Richardson A. Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1131-8. PMID 11451741 DOI: 10.1161/Hq0701.092092  0.332
2001 Friedman JS, Rebel VI, Derby R, Bell K, Huang TT, Kuypers FA, Epstein CJ, Burakoff SJ. Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant. The Journal of Experimental Medicine. 193: 925-34. PMID 11304553 DOI: 10.1084/Jem.193.8.925  0.333
2001 Andreassen OA, Ferrante RJ, Dedeoglu A, Albers DW, Klivenyi P, Carlson EJ, Epstein CJ, Beal MF. Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. Experimental Neurology. 167: 189-95. PMID 11161607 DOI: 10.1006/Exnr.2000.7525  0.344
2001 Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus. The Journal of Biological Chemistry. 276: 2775-9. PMID 11035038 DOI: 10.1074/Jbc.M008216200  0.337
2000 Sago H, Carlson EJ, Smith DJ, Rubin EM, Crnic LS, Huang TT, Epstein CJ. Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome. Pediatric Research. 48: 606-13. PMID 11044479 DOI: 10.1203/00006450-200011000-00009  0.378
2000 Freeman BD, Reaume AG, Swanson PE, Epstein CJ, Carlson EJ, Buchman TG, Karl IE, Hotchkiss RS. Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Critical Care Medicine. 28: 1701-8. PMID 10890606 DOI: 10.1097/00003246-200006000-00001  0.346
2000 Vialard F, Toyama K, Vernoux S, Carlson EJ, Epstein CJ, Sinet PM, Rahmani Z. Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study. Brain Research. Developmental Brain Research. 121: 73-8. PMID 10837894 DOI: 10.1016/S0165-3806(00)00026-2  0.36
2000 Andreassen OA, Ferrante RJ, Klivenyi P, Klein AM, Shinobu LA, Epstein CJ, Beal MF. Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis. Annals of Neurology. 47: 447-55. PMID 10762155 DOI: 10.1002/1531-8249(200004)47:4<447::Aid-Ana7>3.0.Co;2-R  0.33
2000 Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 4386-91. PMID 10737773 DOI: 10.1073/Pnas.080499597  0.313
2000 Huang TT, Carlson EJ, Gillespie AM, Shi Y, Epstein CJ. Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 55: B5-9. PMID 10719757 DOI: 10.1093/Gerona/55.1.B5  0.34
2000 Gum JR, Hicks JW, Gillespie A, Carlson EJ, Rius JL, Epstein CJ, Kim YS. Apoptosis as an anti-neoplastic mechanism in mice expressing a goblet cell-specific hybrid oncogene Gastroenterology. 118: A443. DOI: 10.1016/S0016-5085(00)83883-4  0.323
1999 Huang TT, Carlson EJ, Raineri I, Gillespie AM, Kozy H, Epstein CJ. The use of transgenic and mutant mice to study oxygen free radical metabolism. Annals of the New York Academy of Sciences. 893: 95-112. PMID 10672232 DOI: 10.1111/J.1749-6632.1999.Tb07820.X  0.348
1999 Li Y, Carlson E, Murakami K, Copin JC, Luche R, Chen SF, Epstein CJ, Chan PH. Targeted expression of human CuZn superoxide dismutase gene in mouse central nervous system. Journal of Neuroscience Methods. 89: 49-55. PMID 10476683 DOI: 10.1016/S0165-0270(99)00037-0  0.339
1999 Rando TA, Epstein CJ. Copper/zinc superoxide dismutase: more is not necessarily better! Annals of Neurology. 46: 135-6. PMID 10401795 DOI: 10.1002/1531-8249(199907)46:1<135::Aid-Ana24>3.0.Co;2-Q  0.489
1999 Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. The Journal of Biological Chemistry. 274: 20071-4. PMID 10400615 DOI: 10.1074/Jbc.274.29.20071  0.333
1999 Kamii H, Kato I, Kinouchi H, Chan PH, Epstein CJ, Akabane A, Okamoto H, Yoshimoto T. Amelioration of vasospasm after subarachnoid hemorrhage in transgenic mice overexpressing CuZn-superoxide dismutase. Stroke; a Journal of Cerebral Circulation. 30: 867-71; discussion 8. PMID 10187893 DOI: 10.1161/01.Str.30.4.867  0.324
1999 Gum JR, Hicks JW, Gillespie AM, Carlson EJ, Kömüves L, Karnik S, Hong JC, Epstein CJ, Kim YS. Goblet cell-specific expression mediated by the MUC2 mucin gene promoter in the intestine of transgenic mice. The American Journal of Physiology. 276: G666-76. PMID 10070043 DOI: 10.1152/Ajpgi.1999.276.3.G666  0.302
1999 Van Remmen H, Salvador C, Yang H, Huang TT, Epstein CJ, Richardson A. Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Archives of Biochemistry and Biophysics. 363: 91-7. PMID 10049502 DOI: 10.1006/Abbi.1998.1060  0.341
1999 Melov S, Coskun P, Patel M, Tuinstra R, Cottrell B, Jun AS, Zastawny TH, Dizdaroglu M, Goodman SI, Huang TT, Miziorko H, Epstein CJ, Wallace DC. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 846-51. PMID 9927656 DOI: 10.1073/Pnas.96.3.846  0.315
1999 Welch J, Kermler-Noreuil K, Major H, Qiau Q, Epstein C, Patil S. Atypical Down Syndrome phenotype with translocation Trisomy 21 Genetics in Medicine. 1: 64-64. DOI: 10.1097/00125817-199901000-00094  0.321
1998 Huang TT, Carlson EJ, Gillespie AM, Epstein CJ. Genetic modification of the dilated cardiomyopathy and neonatal lethality phenotype of mice lacking manganese superoxide dismutase. Age. 21: 83-4. PMID 23604356 DOI: 10.1007/S11357-998-0011-Y  0.345
1998 Williams MD, Van Remmen H, Conrad CC, Huang TT, Epstein CJ, Richardson A. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. The Journal of Biological Chemistry. 273: 28510-5. PMID 9774481 DOI: 10.1074/Jbc.273.43.28510  0.332
1998 Horie Y, Wolf R, Flores SC, McCord JM, Epstein CJ, Granger DN. Transgenic mice with increased copper/zinc-superoxide dismutase activity are resistant to hepatic leukostasis and capillary no-reflow after gut ischemia/reperfusion. Circulation Research. 83: 691-6. PMID 9758638 DOI: 10.1161/01.Res.83.7.691  0.327
1998 Rando TA, Crowley RS, Carlson EJ, Epstein CJ, Mohapatra PK. Overexpression of copper/zinc superoxide dismutase: a novel cause of murine muscular dystrophy. Annals of Neurology. 44: 381-6. PMID 9749606 DOI: 10.1002/Ana.410440315  0.484
1998 Cardozo-Pelaez F, Song S, Parthasarathy A, Epstein CJ, Sanchez-Ramos J. Attenuation of age-dependent oxidative damage to DNA and protein in brainstem of Tg Cu/Zn SOD mice. Neurobiology of Aging. 19: 311-6. PMID 9733163 DOI: 10.1016/S0197-4580(98)00067-0  0.323
1998 Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. The Journal of Biological Chemistry. 273: 4296-9. PMID 9468475 DOI: 10.1074/Jbc.273.8.4296  0.314
1997 Kondo T, Reaume AG, Huang TT, Murakami K, Carlson E, Chen S, Scott RW, Epstein CJ, Chan PH. Edema formation exacerbates neurological and histological outcomes after focal cerebral ischemia in CuZn-superoxide dismutase gene knockout mutant mice. Acta Neurochirurgica. Supplement. 70: 62-4. PMID 9416279 DOI: 10.1007/978-3-7091-6837-0_19  0.325
1997 Tribble DL, Gong EL, Leeuwenburgh C, Heinecke JW, Carlson EL, Verstuyft JG, Epstein CJ. Fatty streak formation in fat-fed mice expressing human copper-zinc superoxide dismutase. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1734-40. PMID 9327771 DOI: 10.1161/01.Atv.17.9.1734  0.338
1997 Murakami K, Kondo T, Epstein CJ, Chan PH. Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice. Stroke; a Journal of Cerebral Circulation. 28: 1797-804. PMID 9303028 DOI: 10.1161/01.Str.28.9.1797  0.302
1997 Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. The Journal of Clinical Investigation. 100: 957-62. PMID 9276712 DOI: 10.1172/Jci231  0.325
1997 Huang TT, Yasunami M, Carlson EJ, Gillespie AM, Reaume AG, Hoffman EK, Chan PH, Scott RW, Epstein CJ. Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Archives of Biochemistry and Biophysics. 344: 424-32. PMID 9264557 DOI: 10.1006/Abbi.1997.0237  0.333
1997 Mena MA, Khan U, Togasaki DM, Sulzer D, Epstein CJ, Przedborski S. Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture. Journal of Neurochemistry. 69: 21-33. PMID 9202290 DOI: 10.1046/J.1471-4159.1997.69010021.X  0.302
1997 Kondo T, Reaume AG, Huang TT, Carlson E, Murakami K, Chen SF, Hoffman EK, Scott RW, Epstein CJ, Chan PH. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4180-9. PMID 9151735 DOI: 10.1523/Jneurosci.17-11-04180.1997  0.33
1997 Kikuchi Y, Shimosegawa T, Moriizumi S, Kimura K, Satoh A, Koizumi M, Kato I, Epstein CJ, Toyota T. Transgenic copper/zinc-superoxide dismutase ameliorates caerulein-induced pancreatitis in mice. Biochemical and Biophysical Research Communications. 233: 177-81. PMID 9144418 DOI: 10.1006/Bbrc.1997.6421  0.32
1997 Kostic V, Gurney ME, Deng HX, Siddique T, Epstein CJ, Przedborski S. Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Annals of Neurology. 41: 497-504. PMID 9124807 DOI: 10.1002/Ana.410410413  0.318
1997 Kondo T, Sharp FR, Honkaniemi J, Mikawa S, Epstein CJ, Chan PH. DNA fragmentation and Prolonged expression of c-fos, c-jun, and hsp70 in kainic acid-induced neuronal cell death in transgenic mice overexpressing human CuZn-superoxide dismutase. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 241-56. PMID 9119897 DOI: 10.1097/00004647-199703000-00001  0.338
1997 Sheng P, Wang XB, Ladenheim B, Epstein C, Cadet JL. AP-1 DNA-binding activation by methamphetamine involves oxidative stress. Synapse (New York, N.Y.). 24: 213-7. PMID 8923660 DOI: 10.1002/(Sici)1098-2396(199611)24:3<213::Aid-Syn2>3.0.Co;2-H  0.306
1997 Chetkovich HJ, Ditelberg JS, Chen S, Chan P, Epstein CJ, Ferriero DM. Glutathione Peroxidase Activity Decreases and Hydrogen Peroxide Accumulates after Perinatal Hypoxia-Ischemia in SOD 1 Overexpressing Mice • 1714 Pediatric Research. 41: 288-288. DOI: 10.1203/00006450-199704001-01733  0.336
1996 Epstein CJ, Motulsky AG. Werner syndrome: entering the helicase era. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 1025-7. PMID 8976161 DOI: 10.1002/Bies.950181214  0.492
1996 Kondo T, Murakami K, Honkaniemi J, Sharp FR, Epstein CJ, Chan PH. Expression of hsp70 mRNA is induced in the brain of transgenic mice overexpressing human CuZn-superoxide dismutase following transient global cerebral ischemia. Brain Research. 737: 321-6. PMID 8930384 DOI: 10.1016/0006-8993(96)00949-3  0.322
1996 Holtzman DM, Santucci D, Kilbridge J, Chua-Couzens J, Fontana DJ, Daniels SE, Johnson RM, Chen K, Sun Y, Carlson E, Alleva E, Epstein CJ, Mobley WC. Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 93: 13333-8. PMID 8917591 DOI: 10.1073/Pnas.93.23.13333  0.389
1996 Kamii H, Mikawa S, Murakami K, Kinouchi H, Yoshimoto T, Reola L, Carlson E, Epstein CJ, Chan PH. Effects of nitric oxide synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 1153-7. PMID 8898687 DOI: 10.1097/00004647-199611000-00009  0.322
1996 Mikawa S, Kinouchi H, Kamii H, Gobbel GT, Chen SF, Carlson E, Epstein CJ, Chan PH. Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice. Journal of Neurosurgery. 85: 885-91. PMID 8893728 DOI: 10.3171/Jns.1996.85.5.0885  0.324
1996 Hirata H, Ladenheim B, Carlson E, Epstein C, Cadet JL. Autoradiographic evidence for methamphetamine-induced striatal dopaminergic loss in mouse brain: attenuation in CuZn-superoxide dismutase transgenic mice. Brain Research. 714: 95-103. PMID 8861613 DOI: 10.1016/0006-8993(95)01502-7  0.332
1996 Imaizumi S, Kondo T, Deli MA, Gobbel G, Joó F, Epstein CJ, Yoshimoto T, Chan PH. The influence of oxygen free radicals on the permeability of the monolayer of cultured brain endothelial cells. Neurochemistry International. 29: 205-11. PMID 8837050 DOI: 10.1016/0197-0186(95)00120-4  0.323
1996 Ditelberg JS, Sheldon RA, Epstein CJ, Ferriero DM. Brain injury after perinatal hypoxia-ischemia is exacerbated in copper/zinc superoxide dismutase transgenic mice. Pediatric Research. 39: 204-8. PMID 8825788 DOI: 10.1203/00006450-199602000-00003  0.327
1996 Holtzman DM, Epstein CJ, Mobley WC. The human trisomy 21 brain: Insights from mouse models of Down syndrome Mental Retardation and Developmental Disabilities Research Reviews. 2: 66-72. DOI: 10.1002/(Sici)1098-2779(1996)2:2<66::Aid-Mrdd2>3.0.Co;2-V  0.319
1995 Mikawa S, Sharp FR, Kamii H, Kinouchi H, Epstein CJ, Chan PK. Expression of c-fos and hsp70 mRNA after traumatic brain injury in transgenic mice overexpressing CuZn-superoxide dismutase. Brain Research. Molecular Brain Research. 33: 288-94. PMID 8750888 DOI: 10.1016/0169-328X(95)00146-J  0.312
1995 Chan PH, Epstein CJ, Li Y, Huang TT, Carlson E, Kinouchi H, Yang G, Kamii H, Mikawa S, Kondo T. Transgenic mice and knockout mutants in the study of oxidative stress in brain injury. Journal of Neurotrauma. 12: 815-24. PMID 8594209 DOI: 10.1089/Neu.1995.12.815  0.325
1995 Cadet JL, Ladenheim B, Hirata H, Rothman RB, Ali S, Carlson E, Epstein C, Moran TH. Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn-superoxide dismutase transgenic mice. Synapse (New York, N.Y.). 21: 169-76. PMID 8584978 DOI: 10.1002/Syn.890210210  0.338
1995 Cadet JL, Ali SF, Rothman RB, Epstein CJ. Neurotoxicity, drugs and abuse, and the CuZn-superoxide dismutase transgenic mice. Molecular Neurobiology. 11: 155-63. PMID 8561959 DOI: 10.1007/Bf02740692  0.341
1995 Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH, Wallace DC, Epstein CJ. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nature Genetics. 11: 376-81. PMID 7493016 DOI: 10.1038/Ng1295-376  0.346
1994 Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein P, Epstein CJ, Kamii H. Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 25: 165-70. PMID 8266365 DOI: 10.1161/01.Str.25.1.165  0.306
1994 Miller MW, Duhl DM, Winkes BM, Arredondo-Vega F, Saxon PJ, Wolff GL, Epstein CJ, Hershfield MS, Barsh GS. The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene. The Embo Journal. 13: 1806-16. PMID 8168479  0.488
1994 Kamii H, Kinouchi H, Sharp FR, Koistinaho J, Epstein CJ, Chan PH. Prolonged expression of hsp70 mRNA following transient focal cerebral ischemia in transgenic mice overexpressing CuZn-superoxide dismutase. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 478-86. PMID 8163590 DOI: 10.1038/Jcbfm.1994.59  0.313
1994 Kujirai K, Carlson E, Epstein CJ, Cadet JL. Autoradiographic distribution of mu opioid receptors in the brains of Cu/Zn-superoxide dismutase mice. Synapse (New York, N.Y.). 17: 76-83. PMID 8091304 DOI: 10.1002/Syn.890170203  0.31
1994 Duhl DM, Stevens ME, Vrieling H, Saxon PJ, Miller MW, Epstein CJ, Barsh GS. Pleiotropic effects of the mouse lethal yellow (Ay) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs. Development (Cambridge, England). 120: 1695-708. PMID 8050375  0.494
1994 Shi YP, Huang TT, Carlson EJ, Epstein CJ. The mapping of transgenes by fluorescence in situ hybridization on G-banded mouse chromosomes. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 337-41. PMID 8043947 DOI: 10.1007/Bf00356551  0.314
1994 Kamii H, Kinouchi H, Sharp FR, Epstein CJ, Sagar SM, Chan PH. Expression of c-fos mRNA after a mild focal cerebral ischemia in SOD-1 transgenic mice. Brain Research. 662: 240-4. PMID 7859076 DOI: 10.1016/0006-8993(94)90818-4  0.306
1994 Cadet JL, Ladenheim B, Baum I, Carlson E, Epstein C. CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA) Brain Research. 655: 259-262. PMID 7812784 DOI: 10.1016/0006-8993(94)91624-1  0.326
1993 Cadet JL, Kujirai K, Carlson E, Epstein CJ. Autoradiographic distribution of [3H]neurotensin receptors in the brains of superoxide dismutase transgenic mice. Synapse (New York, N.Y.). 14: 24-33. PMID 8390106 DOI: 10.1002/Syn.890140105  0.338
1993 Chan PH, Kinouchi H, Epstein CJ, Carlson E, Chen SF, Imaizumi S, Yang GY. Role of superoxide dismutase in ischemic brain injury: reduction of edema and infarction in transgenic mice following focal cerebral ischemia. Progress in Brain Research. 96: 97-104. PMID 8332750 DOI: 10.1016/S0079-6123(08)63260-4  0.323
1992 Huang TT, Carlson EJ, Leadon SA, Epstein CJ. Relationship of resistance to oxygen free radicals to CuZn-superoxide dismutase activity in transgenic, transfected, and trisomic cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 903-10. PMID 1740238 DOI: 10.1096/Fasebj.6.3.1740238  0.329
1992 Przedborski S, Jackson-Lewis V, Kostic V, Carlson E, Epstein CJ, Cadet JL. Superoxide dismutase, catalase, and glutathione peroxidase activities in copper/zinc-superoxide dismutase transgenic mice. Journal of Neurochemistry. 58: 1760-7. PMID 1560230 DOI: 10.1111/J.1471-4159.1992.Tb10051.X  0.356
1992 Holtzman DM, Epstein CJ. The molecular genetics of Down syndrome. Molecular Genetic Medicine. 2: 105-20. PMID 1458222 DOI: 10.1016/B978-0-12-462002-5.50009-1  0.323
1992 Berger CN, Epstein CJ. Deficient transformation of murine trisomy 16 fetal liver cells by the Abelson and J2 viruses. Immunology Letters. 33: 47-51. PMID 1427990 DOI: 10.1016/0165-2478(92)90092-3  0.31
1992 Holtzman DM, Bayney RM, Li YW, Khosrovi H, Berger CN, Epstein CJ, Mobley WC. Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome. The Embo Journal. 11: 619-27. PMID 1371464 DOI: 10.1002/J.1460-2075.1992.Tb05094.X  0.318
1991 Korenberg JR, Kalousek DK, Anneren G, Pulst SM, Hall JG, Epstein CJ, Cox DR. Deletion of chromosome 21 and normal intelligence: molecular definition of the lesion. Human Genetics. 87: 112-8. PMID 2066097 DOI: 10.1007/Bf00204163  0.309
1991 Przedborski S, Kostic V, Jackson-Lewis V, Carlson E, Epstein CJ, Cadet JL. Quantitative autoradiographic distribution of [3H]-MPTP binding in the brains of superoxide dismutase transgenic mice. Brain Research Bulletin. 26: 987-91. PMID 1933417 DOI: 10.1016/0361-9230(91)90267-N  0.32
1991 Chan PH, Yang GY, Chen SF, Carlson E, Epstein CJ. Cold-induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn-superoxide dismutase. Annals of Neurology. 29: 482-6. PMID 1859179 DOI: 10.1002/Ana.410290506  0.307
1991 Kinouchi H, Epstein CJ, Mizui T, Carlson E, Chen SF, Chan PH. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 88: 11158-62. PMID 1763030 DOI: 10.1073/Pnas.88.24.11158  0.329
1990 Barsh GS, Lovett M, Epstein CJ. Effects of the lethal yellow (Ay) mutation in mouse aggregation chimeras. Development (Cambridge, England). 109: 683-90. PMID 2401219  0.478
1990 Cadet JL, Przedborski S, Kostic V, Jackson-Lewis V, Carlson E, Epstein CJ. Quantitative autoradiographic distribution of [3H]mazindol-labeled dopamine uptake sites in the brains of superoxide dismutase transgenic mice. Brain Research Bulletin. 25: 187-92. PMID 2119856 DOI: 10.1016/0361-9230(90)90274-4  0.319
1989 Berger CN, Epstein CJ. Genomic imprinting: normal complementation of murine chromosome 16. Genetical Research. 54: 227-30. PMID 2620822 DOI: 10.1017/S001667230002869X  0.336
1989 Barsh GS, Epstein CJ. The long-range restriction map surrounding the mouse agouti locus reveals a disparity between physical and genetic distances. Genomics. 5: 9-18. PMID 2570033 DOI: 10.1016/0888-7543(89)90080-3  0.518
1989 Barsh GS, Epstein CJ. Physical and genetic characterization of a 75-kilobase deletion associated with al, a recessive lethal allele at the mouse agouti locus. Genetics. 121: 811-8. PMID 2566558  0.486
1989 Ault B, Caviedes P, Hidalgo J, Epstein CJ, Rapoport SI. Electrophysiological analysis of cultured fetal mouse dorsal root ganglion neurons transgenic for human superoxide dismutase-1, a gene in the Down syndrome region of chromosome 21. Brain Research. 497: 191-4. PMID 2529019 DOI: 10.1016/0006-8993(89)90988-8  0.321
1988 Annerén G, Epstein CJ. Phosphofructokinase activity in normal diploid mice during development and in trisomy 16 fetal mice. Upsala Journal of Medical Sciences. 93: 33-8. PMID 2967575 DOI: 10.1517/03009734000000034  0.373
1987 Lovett M, Goldgaber D, Ashley P, Cox DR, Gajdusek DC, Epstein CJ. The mouse homolog of the human amyloid beta protein (AD-AP) gene is located on the distal end of mouse chromosome 16: further extension of the homology between human chromosome 21 and mouse chromosome 16. Biochemical and Biophysical Research Communications. 144: 1069-75. PMID 3555492 DOI: 10.1016/S0006-291X(87)80073-6  0.326
1987 Moreno PA, Epstein CJ. Enhanced susceptibility of mouse embryos heterozygous for oligosyndactyly (Os/+) to mitomycin C-induced skeletal abnormalities. Teratology. 35: 261-5. PMID 3037716 DOI: 10.1002/Tera.1420350213  0.341
1987 Epstein CJ, Avraham KB, Lovett M, Smith S, Elroy-Stein O, Rotman G, Bry C, Groner Y. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 84: 8044-8. PMID 2960971 DOI: 10.1073/Pnas.84.22.8044  0.35
1987 Annerén KG, Korenberg JR, Epstein CJ. Phosphofructokinase activity in fibroblasts aneuploid for chromosome 21. Human Genetics. 76: 63-5. PMID 2952576 DOI: 10.1007/Bf00283052  0.323
1987 Annerén KG, Epstein CJ. Lipid peroxidation and superoxide dismutase-1 and glutathione peroxidase activities in trisomy 16 fetal mice and human trisomy 21 fibroblasts. Pediatric Research. 21: 88-92. PMID 2948148 DOI: 10.1203/00006450-198701000-00019  0.321
1987 Lovett M, Epstein CJ. The lethal yellow allele-associated provirus results in the production of chimeric viral-host RNAs. Proceedings of the National Academy of Sciences of the United States of America. 84: 2853-7. PMID 2437585 DOI: 10.1073/Pnas.84.9.2853  0.319
1985 Magnuson T, Debrot S, Dimpfl J, Zweig A, Zamora T, Epstein CJ. The early lethality of autosomal monosomy in the mouse. The Journal of Experimental Zoology. 236: 353-60. PMID 4086989 DOI: 10.1002/Jez.1402360313  0.584
1985 Epstein CJ, Hofmeister BG, Yee D, Smith SA, Philip R, Cox DR, Epstein LB. Stem cell deficiencies and thymic abnormalities in fetal mouse trisomy 16. The Journal of Experimental Medicine. 162: 695-712. PMID 3160808 DOI: 10.1084/Jem.162.2.695  0.355
1985 Cox DR, Epstein CJ. Comparative gene mapping of human chromosome 21 and mouse chromosome 16. Annals of the New York Academy of Sciences. 450: 169-77. PMID 3160288 DOI: 10.1111/J.1749-6632.1985.Tb21491.X  0.304
1985 Epstein CJ. Mouse monosomies and trisomies as experimental systems for studying mammalian aneuploidy Trends in Genetics. 1: 129-134. DOI: 10.1016/0168-9525(85)90054-X  0.351
1984 Lovett M, Cox DR, Yee D, Boll W, Weissmann C, Epstein CJ, Epstein LB. The chromosomal location of mouse interferon alpha genes. The Embo Journal. 3: 1643-6. PMID 6745245 DOI: 10.1002/J.1460-2075.1984.Tb02023.X  0.32
1984 Cox DR, Smith SA, Epstein LB, Epstein CJ. Mouse trisomy 16 as an animal model of human trisomy 21 (Down syndrome): production of viable trisomy 16 diploid mouse chimeras. Developmental Biology. 101: 416-24. PMID 6229437 DOI: 10.1016/0012-1606(84)90156-8  0.345
1984 Magnuson T, Epstein CJ. Oligosyndactyly: a lethal mutation in the mouse that results in mitotic arrest very early in development. Cell. 38: 823-33. PMID 6091901 DOI: 10.1016/0092-8674(84)90277-0  0.305
1983 Epstein CJ. Sex chromosome expression in embryonic development. Differentiation; Research in Biological Diversity. 23: S31-4. PMID 6444171 DOI: 10.1007/978-3-642-69150-8_5  0.323
1983 Epstein CJ, Smith S, Cox DR. Production and properties of mouse trisomy 15  diploid chimeras Developmental Genetics. 4: 159-165. DOI: 10.1002/Dvg.1020040303  0.325
1982 Magnuson T, Epstein CJ, Silver LM, Martin GR. Pluripotent embryonic stem cell lines can be derived from tw5/tw5 blastocysts. Nature. 298: 750-3. PMID 7110310 DOI: 10.1038/298750A0  0.595
1982 Epstein CJ, Smith SA, Zamora T, Sawicki JA, Magnuson TR, Cox DR. Production of viable adult trisomy 17 reversible diploid mouse chimeras. Proceedings of the National Academy of Sciences of the United States of America. 79: 4376-80. PMID 6956868 DOI: 10.1073/Pnas.79.14.4376  0.58
1982 Cox DR, Sawicki JA, Yee D, Appella E, Epstein CJ. Assignment of the gene for beta 2-microglobulin (B2m) to mouse chromosome 2. Proceedings of the National Academy of Sciences of the United States of America. 79: 1930-4. PMID 6177004 DOI: 10.1073/Pnas.79.6.1930  0.355
1981 Magnuson T, Epstein CJ. Genetic control of very early mammalian development. Biological Reviews of the Cambridge Philosophical Society. 56: 369-408. PMID 7030419 DOI: 10.1111/J.1469-185X.1981.Tb00354.X  0.325
1981 Sawicki JA, Magnuson T, Epstein CJ. Evidence for expression of the paternal genome in the two-cell mouse embryo. Nature. 294: 450-1. PMID 6171732 DOI: 10.1038/294450A0  0.323
1980 Bartley JA, Epstein CJ. Gene dosage effect for glycinamide ribonucleotide synthetase in human fibroblasts trisomic for chromosome 21. Biochemical and Biophysical Research Communications. 93: 1286-9. PMID 6446912 DOI: 10.1016/0006-291X(80)90629-4  0.326
1980 Weil J, Epstein LB, Epstein CJ. Synthesis of interferon-induced polypeptides in normal and chromosome 21-aneuploid human fibroblasts: relationship to relative sensitivities in antiviral assays. Journal of Interferon Research. 1: 111-24. PMID 6180034 DOI: 10.1089/Jir.1980.1.111  0.308
1980 Epstein LB, Cox DR, Epstein CJ. Assignment of the genes for sensitivity to interferon [IfRec] and soluble superoxide dismutase [SOD-1] to mouse chromosome. Annals of the New York Academy of Sciences. 350: 171-3. PMID 6165271 DOI: 10.1111/J.1749-6632.1980.Tb20618.X  0.334
1980 Cox DR, Epstein LB, Epstein CJ. Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16. Proceedings of the National Academy of Sciences of the United States of America. 77: 2168-72. PMID 6154946 DOI: 10.1073/Pnas.77.4.2168  0.357
1979 Epstein CJ, Travis B. Preimplantation lethality of monosomy for mouse chromosome 19. Nature. 280: 144-5. PMID 552603 DOI: 10.1038/280144A0  0.348
1979 Blau HM, Epstein CJ. Manipulation of myogenesis in vitro: reversible inhibition by DMSO. Cell. 17: 95-108. PMID 455462 DOI: 10.1016/0092-8674(79)90298-8  0.511
1979 Drasner K, Epstein CJ, Epstein LB. The antiproliferative effects of interferon on murine embryonic cells. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 160: 46-9. PMID 419124 DOI: 10.3181/00379727-160-40385  0.302
1978 Martin GR, Epstein CJ, Martin DW. Use of teratocarcinoma stem cells as a model system for the study of X-chromosome inactivation in vitro. Basic Life Sciences. 12: 269-95. PMID 752322 DOI: 10.1007/978-1-4684-3390-6_21  0.581
1978 Martin GR, Smith S, Epstein CJ. Protein synthetic patterns in teratocarcinoma stem cells and mouse embryos at early stages of development. Developmental Biology. 66: 8-16. PMID 751845 DOI: 10.1016/0012-1606(78)90269-5  0.563
1978 Epstein CJ, Smith S, Travis B, Tucker G. Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos. Nature. 274: 500-3. PMID 672979 DOI: 10.1038/274500A0  0.317
1978 Martin GR, Epstein CJ, Travis B, Tucker G, Yatziv S, Martin DW, Clift S, Cohen S. X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro. Nature. 271: 329-33. PMID 563984 DOI: 10.1038/271329A0  0.58
1978 Epstein CJ, Travis B, Tucker G, Smith S. The direct demonstration of an X-chromosome dosage effect prior to inactivation. Basic Life Sciences. 12: 261-7. PMID 378216 DOI: 10.1007/978-1-4684-3390-6_20  0.335
1977 Epstein CJ, Tucker G, Travis B, Gropp A. Gene dosage for isocitrate dehydrogenase in mouse embryos trisomic for chromosome 1. Nature. 267: 615-6. PMID 876380 DOI: 10.1038/267615A0  0.361
1975 Mangia F, Abbo-Halbasch G, Epstein CJ. X chromosome expression during oogenesis in the mouse. Developmental Biology. 45: 366-8. PMID 1193304 DOI: 10.1016/0012-1606(75)90074-3  0.345
1975 Erickson RP, Hoppe PC, Tennenbaum D, Spielmann H, Epstein CJ. Lactate dehydrogenase X: effects of antibody on mouse gametes but not on early development. Science (New York, N.Y.). 188: 261-3. PMID 1167979 DOI: 10.1126/Science.1167979  0.328
1975 Epstein CJ. Gene expression and macromolecular synthesis during preimplantation embryonic development. Biology of Reproduction. 12: 82-105. PMID 1095089 DOI: 10.1095/Biolreprod12.1.82  0.317
1974 Tan YH, Schneider EL, Tischfield J, Epstein CJ, Ruddle FH. Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (New York, N.Y.). 186: 61-3. PMID 4371269 DOI: 10.1126/Science.186.4158.61  0.311
1972 Epstein CJ, Weston JA, Whitten WK, Russell ES. The expression of the isocitrate dehydrogenase locus (Id-1) during mouse embryogenesis Developmental Biology. 27: 430-433. PMID 5019139 DOI: 10.1016/0012-1606(72)90182-0  0.32
1972 Epstein CJ. Expression of the mammalian X chromosome before and after fertilization. Science (New York, N.Y.). 175: 1467-8. PMID 5013677 DOI: 10.1126/Science.175.4029.1467  0.329
1970 Epstein CJ, Smith CW, Kwok LW. The characterization of glucose-6-phosphate dehydrogenase in mouse ova. Journal of Reproduction and Fertility. 21: 179-81. PMID 5413349 DOI: 10.1530/Jrf.0.0210179  0.309
1969 Epstein CJ. Mammalian oocytes: X chromosome activity. Science (New York, N.Y.). 163: 1078-9. PMID 5764873 DOI: 10.1126/Science.163.3871.1078  0.352
1968 Epstein CJ, Graham CB, Hodgkin WE, Hecht F, Motulsky AG. Hereditary dysplasia of bone with kyphoscoliosis, contractures, and abnormally shaped ears. The Journal of Pediatrics. 73: 379-86. PMID 5667420 DOI: 10.1016/S0022-3476(68)80115-5  0.486
1966 Epstein CJ, Martin GM, Schultz AL, Motulsky AG. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine. 45: 177-221. PMID 5327241 DOI: 10.1097/00005792-196605000-00001  0.478
1965 Epstein CJ, Martin GM, Motulsky AG. Werner's syndrome; caricature of aging. A genetic model for the study of degenerative diseases. Transactions of the Association of American Physicians. 78: 73-81. PMID 5864984  0.418
1965 Epstein CJ, Motulsky AG. Evolutionary origins of human proteins. Progress in Medical Genetics. 4: 85-127. PMID 5319298  0.398
1963 GOLDBERGER RF, EPSTEIN CJ, ANFINSEN CB. Acceleration of reactivation of reduced bovine pancreatic ribonuclease by a microsomal system from rat liver. The Journal of Biological Chemistry. 238: 628-35. PMID 13948694  0.423
1963 Epstein CJ, Goldberger RF, Anfinsen CB. The Genetic Control of Tertiary Protein Structure: Studies With Model Systems Cold Spring Harbor Symposia On Quantitative Biology. 28: 439-449. DOI: 10.1101/Sqb.1963.028.01.060  0.501
1962 EPSTEIN CJ, ANFINSEN CB. The reversible reduction of disulfide bonds in trypsin and ribonuclease coupled to carboxymethyl cellulose. The Journal of Biological Chemistry. 237: 2175-9. PMID 13890416  0.409
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