Charles J. Epstein, M.D. - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Medical Genetics
Website:
https://en.wikipedia.org/wiki/Charles_Epstein_(geneticist)

259 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Motulsky A, Epstein CJ. 2010 Victor A. McKusick Leadership Award introduction and address. American Journal of Human Genetics. 88: 269-72. PMID 21516616 DOI: 10.1016/j.ajhg.2011.01.012  1
2010 Miller DT, Adam MP, Aradhya S, Biesecker LG, Brothman AR, Carter NP, Church DM, Crolla JA, Eichler EE, Epstein CJ, Faucett WA, Feuk L, Friedman JM, Hamosh A, Jackson L, et al. Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies. American Journal of Human Genetics. 86: 749-64. PMID 20466091 DOI: 10.1016/j.ajhg.2010.04.006  1
2010 Kim A, Joseph S, Khan A, Epstein CJ, Sobel R, Huang TT. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radical Biology & Medicine. 48: 1501-12. PMID 20188820 DOI: 10.1016/j.freeradbiomed.2010.02.028  1
2009 Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1212-20. PMID 19776219 DOI: 10.1093/gerona/glp132  1
2009 Ishihara K, Amano K, Takaki E, Ebrahim AS, Shimohata A, Shibazaki N, Inoue I, Takaki M, Ueda Y, Sago H, Epstein CJ, Yamakawa K. Increased lipid peroxidation in Down's syndrome mouse models. Journal of Neurochemistry. 110: 1965-76. PMID 19645748 DOI: 10.1111/j.1471-4159.2009.06294.x  1
2009 Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Overexpression of Mn superoxide dismutase does not increase life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1114-25. PMID 19633237 DOI: 10.1093/gerona/glp100  1
2009 Pérez VI, Van Remmen H, Bokov A, Epstein CJ, Vijg J, Richardson A. The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell. 8: 73-5. PMID 19077044 DOI: 10.1111/j.1474-9726.2008.00449.x  1
2009 Larosche I, Choumar A, Fromenty B, Lettéron P, Abbey-Toby A, Van Remmen H, Epstein CJ, Richardson A, Feldmann G, Pessayre D, Mansouri A. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates. Toxicology and Applied Pharmacology. 234: 326-38. PMID 19063909 DOI: 10.1016/j.taap.2008.11.004  1
2009 Epstein CJ. Educational Strategies in Genomic Medicine Genomic and Personalized Medicine, Two-Vol Set. 401-413. DOI: 10.1016/B978-0-12-369420-1.00034-2  1
2008 Canzonetta C, Mulligan C, Deutsch S, Ruf S, O'Doherty A, Lyle R, Borel C, Lin-Marq N, Delom F, Groet J, Schnappauf F, De Vita S, Averill S, Priestley JV, Martin JE, ... ... Epstein CJ, et al. DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. American Journal of Human Genetics. 83: 388-400. PMID 18771760 DOI: 10.1016/j.ajhg.2008.08.012  1
2008 Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Epstein CJ, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/vir.0.2008/001255-0  1
2008 Watson MS, Epstein C, Howell RR, Jones MC, Korf BR, McCabe ER, Simpson JL. Developing a national collaborative study system for rare genetic diseases. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 10: 325-9. PMID 18496030 DOI: 10.1097/GIM.0b013e31817b80fd  1
2008 Han ES, Muller FL, Pérez VI, Qi W, Liang H, Xi L, Fu C, Doyle E, Hickey M, Cornell J, Epstein CJ, Roberts LJ, Van Remmen H, Richardson A. The in vivo gene expression signature of oxidative stress. Physiological Genomics. 34: 112-26. PMID 18445702 DOI: 10.1152/physiolgenomics.00239.2007  1
2007 Belichenko PV, Kleschevnikov AM, Salehi A, Epstein CJ, Mobley WC. Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships. The Journal of Comparative Neurology. 504: 329-45. PMID 17663443 DOI: 10.1002/cne.21433  1
2007 Klein OD, Cotter PD, Moore MW, Zanko A, Gilats M, Epstein CJ, Conte F, Rauen KA. Interstitial deletions of chromosome 6q: genotype-phenotype correlation utilizing array CGH. Clinical Genetics. 71: 260-6. PMID 17309649 DOI: 10.1111/j.1399-0004.2007.00757.x  1
2006 Antonarakis SE, Epstein CJ. The challenge of Down syndrome. Trends in Molecular Medicine. 12: 473-9. PMID 16935027 DOI: 10.1016/j.molmed.2006.08.005  1
2006 Epstein CJ. Medical genetics in the genomic medicine of the 21st century. American Journal of Human Genetics. 79: 434-8. PMID 16909381 DOI: 10.1086/507610  1
2006 Shukkur EA, Shimohata A, Akagi T, Yu W, Yamaguchi M, Murayama M, Chui D, Takeuchi T, Amano K, Subramhanya KH, Hashikawa T, Sago H, Epstein CJ, Takashima A, Yamakawa K. Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome. Human Molecular Genetics. 15: 2752-62. PMID 16891409 DOI: 10.1093/hmg/ddl211  1
2006 Erker L, Schubert R, Elchuri S, Huang TT, Tarin D, Mueller K, Zielen S, Epstein CJ, Wynshaw-Boris A. Effect of the reduction of superoxide dismutase 1 and 2 or treatment with alpha-tocopherol on tumorigenesis in Atm-deficient mice. Free Radical Biology & Medicine. 41: 590-600. PMID 16863992 DOI: 10.1016/j.freeradbiomed.2006.04.032  1
2006 Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, ... ... Epstein CJ, et al. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron. 51: 29-42. PMID 16815330 DOI: 10.1016/j.neuron.2006.05.022  1
2006 Epstein CJ. Down's syndrome: critical genes in a critical region. Nature. 441: 582-3. PMID 16738647 DOI: 10.1038/441582a  1
2006 Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, Huang TT, Epstein CJ, Roberts LJ, Csete M, Faulkner JA, Van Remmen H. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radical Biology & Medicine. 40: 1993-2004. PMID 16716900 DOI: 10.1016/j.freeradbiomed.2006.01.036  1
2006 Huang TT, Naeemuddin M, Elchuri S, Yamaguchi M, Kozy HM, Carlson EJ, Epstein CJ. Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Human Molecular Genetics. 15: 1187-94. PMID 16497723 DOI: 10.1093/hmg/ddl034  1
2006 Clarke SL, Vasanthakumar A, Anderson SA, Pondarré C, Koh CM, Deck KM, Pitula JS, Epstein CJ, Fleming MD, Eisenstein RS. Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster. The Embo Journal. 25: 544-53. PMID 16424901 DOI: 10.1038/sj.emboj.7600954  1
2006 Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H. Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mechanisms of Ageing and Development. 127: 298-306. PMID 16405961 DOI: 10.1016/j.mad.2005.11.004  1
2005 Epstein CJ. Medical geneticists in the 21st century. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 7: 375-9. PMID 16024968 DOI: 10.1097/01.GIM.0000170771.50414.79  1
2005 Siarey RJ, Villar AJ, Epstein CJ, Galdzicki Z. Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome. Neuropharmacology. 49: 122-8. PMID 15992587 DOI: 10.1016/j.neuropharm.2005.02.012  1
2005 Villar AJ, Belichenko PV, Gillespie AM, Kozy HM, Mobley WC, Epstein CJ. Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 79-90. PMID 15859352 DOI: 10.1007/s00335-004-2428-7  1
2005 Zhao Y, Chaiswing L, Oberley TD, Batinic-Haberle I, St Clair W, Epstein CJ, St Clair D. A mechanism-based antioxidant approach for the reduction of skin carcinogenesis. Cancer Research. 65: 1401-5. PMID 15735027 DOI: 10.1158/0008-5472.CAN-04-3334  1
2005 Lynn S, Huang EJ, Elchuri S, Naeemuddin M, Nishinaka Y, Yodoi J, Ferriero DM, Epstein CJ, Huang TT. Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice. Free Radical Biology & Medicine. 38: 817-28. PMID 15721992 DOI: 10.1016/j.freeradbiomed.2004.12.020  1
2005 Dauphinot L, Lyle R, Rivals I, Dang MT, Moldrich RX, Golfier G, Ettwiller L, Toyama K, Rossier J, Personnaz L, Antonarakis SE, Epstein CJ, Sinet PM, Potier MC. The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome. Human Molecular Genetics. 14: 373-84. PMID 15590701 DOI: 10.1093/hmg/ddi033  1
2005 Villar AJ, Kim J, De Blank P, Gillespie AM, Kozy HM, Ursell PC, Epstein CJ. Effects of genetic background on cardiovascular anomalies in the Ts16 mouse. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 131-9. PMID 15580624 DOI: 10.1002/dvdy.20216  1
2005 Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, Epstein CJ, Huang TT. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene. 24: 367-80. PMID 15531919 DOI: 10.1038/sj.onc.1208207  1
2004 Belichenko PV, Masliah E, Kleschevnikov AM, Villar AJ, Epstein CJ, Salehi A, Mobley WC. Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome. The Journal of Comparative Neurology. 480: 281-98. PMID 15515178 DOI: 10.1002/cne.20337  1
2004 Ali SS, Hardt JI, Quick KL, Kim-Han JS, Erlanger BF, Huang TT, Epstein CJ, Dugan LL. A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties. Free Radical Biology & Medicine. 37: 1191-202. PMID 15451059 DOI: 10.1016/j.freeradbiomed.2004.07.002  1
2004 Kleschevnikov AM, Belichenko PV, Villar AJ, Epstein CJ, Malenka RC, Mobley WC. Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8153-60. PMID 15371516 DOI: 10.1523/JNEUROSCI.1766-04.2004  1
2004 Epstein CJ. Genetic testing: hope or hype? Genetics in Medicine : Official Journal of the American College of Medical Genetics. 6: 165-72. PMID 15266203 DOI: 10.1097/01.GIM.0000132683.24854.44  1
2004 Olson LE, Roper RJ, Baxter LL, Carlson EJ, Epstein CJ, Reeves RH. Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 230: 581-9. PMID 15188443 DOI: 10.1002/dvdy.20079  1
2004 Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radical Biology & Medicine. 36: 1625-34. PMID 15182862 DOI: 10.1016/j.freeradbiomed.2004.03.016  1
2004 Amano K, Sago H, Uchikawa C, Suzuki T, Kotliarova SE, Nukina N, Epstein CJ, Yamakawa K. Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome. Human Molecular Genetics. 13: 1333-40. PMID 15138197 DOI: 10.1093/hmg/ddh154  1
2004 McArdle A, van der Meulen J, Close GL, Pattwell D, Van Remmen H, Huang TT, Richardson AG, Epstein CJ, Faulkner JA, Jackson MJ. Role of mitochondrial superoxide dismutase in contraction-induced generation of reactive oxygen species in skeletal muscle extracellular space. American Journal of Physiology. Cell Physiology. 286: C1152-8. PMID 15075214 DOI: 10.1152/ajpcell.00322.2003  1
2003 Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiological Genomics. 16: 29-37. PMID 14679299 DOI: 10.1152/physiolgenomics.00122.2003  1
2003 Toren A, Rozenfeld-Granot G, Heath KE, Amariglio N, Rocca B, Crosson J, Epstein CJ, Laghi F, Landolfi R, Carlsson LE, Argraves S, Bizzaro N, Moxey-Mims M, Brok-Simoni F, Martignetti JA, et al. MYH9 spectrum of autosomal-dominant giant platelet syndromes: unexpected association with fibulin-1 variant-D inactivation. American Journal of Hematology. 74: 254-62. PMID 14635206 DOI: 10.1002/ajh.10425  1
2003 Epstein CJ. Is modern genetics the new eugenics? Genetics in Medicine : Official Journal of the American College of Medical Genetics. 5: 469-75. PMID 14614400 DOI: 10.1097/01.GIM.0000093978.77435.17  1
2003 Sutton VR, McAlister WH, Bertin TK, Kaffe S, Wang JC, Yano S, Shaffer LG, Lee B, Epstein CJ, Villar AJ. Skeletal defects in paternal uniparental disomy for chromosome 14 are re-capitulated in the mouse model (paternal uniparental disomy 12). Human Genetics. 113: 447-51. PMID 12938037 DOI: 10.1007/s00439-003-0981-x  1
2003 Cataldo AM, Petanceska S, Peterhoff CM, Terio NB, Epstein CJ, Villar A, Carlson EJ, Staufenbiel M, Nixon RA. App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6788-92. PMID 12890772  1
2003 Coling DE, Yu KC, Somand D, Satar B, Bai U, Huang TT, Seidman MD, Epstein CJ, Mhatre AN, Lalwani AK. Effect of SOD1 overexpression on age- and noise-related hearing loss. Free Radical Biology & Medicine. 34: 873-80. PMID 12654476 DOI: 10.1016/S0891-5849(02)01439-9  1
2002 Hawgood S, Ochs M, Jung A, Akiyama J, Allen L, Brown C, Edmondson J, Levitt S, Carlson E, Gillespie AM, Villar A, Epstein CJ, Poulain FR. Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L1002-10. PMID 12376353 DOI: 10.1152/ajplung.00118.2002  1
2002 Zhao Y, Oberley TD, Chaiswing L, Lin SM, Epstein CJ, Huang TT, St Clair D. Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model. Oncogene. 21: 3836-46. PMID 12032821 DOI: 10.1038/sj.onc.1205477  1
2002 Huang TT, Raineri I, Eggerding F, Epstein CJ. Transgenic and mutant mice for oxygen free radical studies. Methods in Enzymology. 349: 191-213. PMID 11912909 DOI: 10.1016/S0076-6879(02)49335-4  1
2002 Morise Z, Ueda M, Kitajima M, Epstein CJ, Granger DN, Grisham MB. Reactive oxygen species and vascular cell adhesion molecule-1 in distant organ failure following bile duct obstruction in mice. Digestive Diseases and Sciences. 47: 607-13. PMID 11911350 DOI: 10.1023/A:1017980406036  1
2002 Richtsmeier JT, Zumwalt A, Carlson EJ, Epstein CJ, Reeves RH. Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome. American Journal of Medical Genetics. 107: 317-24. PMID 11840489 DOI: 10.1002/ajmg.10175  1
2002 Plump AS, Erskine L, Sabatier C, Brose K, Epstein CJ, Goodman CS, Mason CA, Tessier-Lavigne M. Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron. 33: 219-32. PMID 11804570 DOI: 10.1016/S0896-6273(01)00586-4  1
2002 Asikainen TM, Huang TT, Taskinen E, Levonen AL, Carlson E, Lapatto R, Epstein CJ, Raivio KO. Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity. Free Radical Biology & Medicine. 32: 175-86. PMID 11796207 DOI: 10.1016/S0891-5849(01)00776-6  1
2002 Yang B, Bankir L, Gillespie A, Epstein CJ, Verkman AS. Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. The Journal of Biological Chemistry. 277: 10633-7. PMID 11792714 DOI: 10.1074/jbc.M200207200  1
2002 Epstein CJ. 2001 William Allan Award Address. From Down syndrome to the "human" in "human genetics". American Journal of Human Genetics. 70: 300-13. PMID 11791206 DOI: 10.1086/338915  1
2001 Horowitz MJ, Field NP, Zanko A, Donnelly EF, Epstein C, Longo F. Psychological impact of news of genetic risk for Huntington disease. American Journal of Medical Genetics. 103: 188-92. PMID 11745989 DOI: 10.1002/ajmg.1538  1
2001 Huang TT, Carlson EJ, Kozy HM, Mantha S, Goodman SI, Ursell PC, Epstein CJ. Genetic modification of prenatal lethality and dilated cardiomyopathy in Mn superoxide dismutase mutant mice. Free Radical Biology & Medicine. 31: 1101-10. PMID 11677043 DOI: 10.1016/S0891-5849(01)00694-3  1
2001 Raineri I, Carlson EJ, Gacayan R, Carra S, Oberley TD, Huang TT, Epstein CJ. Strain-dependent high-level expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility. Free Radical Biology & Medicine. 31: 1018-30. PMID 11595386 DOI: 10.1016/S0891-5849(01)00686-4  1
2001 Heath KE, Campos-Barros A, Toren A, Rozenfeld-Granot G, Carlsson LE, Savige J, Denison JC, Gregory MC, White JG, Barker DF, Greinacher A, Epstein CJ, Glucksman MJ, Martignetti JA. Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. American Journal of Human Genetics. 69: 1033-45. PMID 11590545 DOI: 10.1086/324267  1
2001 Villar AJ, Carlson EJ, Gillespie AM, Ursell PC, Epstein CJ. Cardiomyopathy in mice with paternal uniparental disomy for chromosome 12. Genesis (New York, N.Y. : 2000). 30: 274-9. PMID 11536434 DOI: 10.1002/gene.1074  1
2001 Van Remmen H, Williams MD, Guo Z, Estlack L, Yang H, Carlson EJ, Epstein CJ, Huang TT, Richardson A. Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1422-32. PMID 11514315  1
2001 Cooper JD, Salehi A, Delcroix JD, Howe CL, Belichenko PV, Chua-Couzens J, Kilbridge JF, Carlson EJ, Epstein CJ, Mobley WC. Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proceedings of the National Academy of Sciences of the United States of America. 98: 10439-44. PMID 11504920 DOI: 10.1073/pnas.181219298  1
2001 Sha SH, Zajic G, Epstein CJ, Schacht J. Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss. Audiology & Neuro-Otology. 6: 117-23. PMID 11474137 DOI: 10.1159/000046818  1
2001 Guo Z, Van Remmen H, Yang H, Chen X, Mele J, Vijg J, Epstein CJ, Ho YS, Richardson A. Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1131-8. PMID 11451741  1
2001 Gum JR, Hicks JW, Gillespie AM, Rius JL, Treseler PA, Kogan SC, Carlson EJ, Epstein CJ, Kim YS. Mouse intestinal goblet cells expressing SV40 T antigen directed by the MUC2 mucin gene promoter undergo apoptosis upon migration to the villi. Cancer Research. 61: 3472-9. PMID 11309310  1
2001 Friedman JS, Rebel VI, Derby R, Bell K, Huang TT, Kuypers FA, Epstein CJ, Burakoff SJ. Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant. The Journal of Experimental Medicine. 193: 925-34. PMID 11304553 DOI: 10.1084/jem.193.8.925  1
2001 Ranganathan AC, Nelson KK, Rodriguez AM, Kim KH, Tower GB, Rutter JL, Brinckerhoff CE, Huang TT, Epstein CJ, Jeffrey JJ, Melendez JA. Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. The Journal of Biological Chemistry. 276: 14264-70. PMID 11297530 DOI: 10.1074/jbc.M100199200  1
2001 Epperly MW, Travis EL, Whitsett JA, Raineri I, Epstein CJ, Greenberger JS. Overexpression of manganese superoxide dismutase (MnSOD) in whole lung or alveolar type II cells of MnSOD transgenic mice does not provide intrinsic lung irradiation protection. International Journal of Cancer. Journal International Du Cancer. 96: 11-21. PMID 11241326 DOI: 10.1002/1097-0215(20010220)96:1<11::AID-IJC2>3.0.CO;2-R  1
2001 Andreassen OA, Ferrante RJ, Dedeoglu A, Albers DW, Klivenyi P, Carlson EJ, Epstein CJ, Beal MF. Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. Experimental Neurology. 167: 189-95. PMID 11161607 DOI: 10.1006/exnr.2000.7525  1
2001 Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus. The Journal of Biological Chemistry. 276: 2775-9. PMID 11035038 DOI: 10.1074/jbc.M008216200  1
2000 Epstein CJ. Some ethical implications of the Human Genome Project. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 2: 193-7. PMID 11256665  1
2000 Toren A, Rozenfeld-Granot G, Rocca B, Epstein CJ, Amariglio N, Laghi F, Landolfi R, Brok-Simoni F, Carlsson LE, Rechavi G, Greinacher A. Autosomal-dominant giant platelet syndromes: a hint of the same genetic defect as in Fechtner syndrome owing to a similar genetic linkage to chromosome 22q11-13. Blood. 96: 3447-51. PMID 11071640  1
2000 Sago H, Carlson EJ, Smith DJ, Rubin EM, Crnic LS, Huang TT, Epstein CJ. Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome. Pediatric Research. 48: 606-13. PMID 11044479 DOI: 10.1203/00006450-200011000-00009  1
2000 Chen Z, Oberley TD, Ho Y, Chua CC, Siu B, Hamdy RC, Epstein CJ, Chua BH. Overexpression of CuZnSOD in coronary vascular cells attenuates myocardial ischemia/reperfusion injury. Free Radical Biology & Medicine. 29: 589-96. PMID 11033410 DOI: 10.1016/S0891-5849(00)00363-4  1
2000 Epperly MW, Epstein CJ, Travis EL, Greenberger JS. Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-Plasmid/Liposome (SOD2-PL) intratracheal gene therapy. Radiation Research. 154: 365-74. PMID 11023599  1
2000 Karliner JS, Honbo N, Epstein CJ, Xian M, Lau YF, Gray MO. Neonatal mouse cardiac myocytes exhibit cardioprotection induced by hypoxic and pharmacologic preconditioning and by transgenic overexpression of human Cu/Zn superoxide dismutase. Journal of Molecular and Cellular Cardiology. 32: 1779-86. PMID 11013122 DOI: 10.1006/jmcc.2000.1212  1
2000 Akgür FM, Brown MF, Zibari GB, McDonald JC, Epstein CJ, Ross CR, Granger DN. Role of superoxide in hemorrhagic shock-induced P-selectin expression. American Journal of Physiology. Heart and Circulatory Physiology. 279: H791-7. PMID 10924079  1
2000 Freeman BD, Reaume AG, Swanson PE, Epstein CJ, Carlson EJ, Buchman TG, Karl IE, Hotchkiss RS. Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Critical Care Medicine. 28: 1701-8. PMID 10890606  1
2000 Russell J, Epstein CJ, Grisham MB, Alexander JS, Yeh KY, Granger DN. Regulation of E-selectin expression in postischemic intestinal microvasculature. American Journal of Physiology. Gastrointestinal and Liver Physiology. 278: G878-85. PMID 10859217  1
2000 Vialard F, Toyama K, Vernoux S, Carlson EJ, Epstein CJ, Sinet PM, Rahmani Z. Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study. Brain Research. Developmental Brain Research. 121: 73-8. PMID 10837894 DOI: 10.1016/S0165-3806(00)00026-2  1
2000 Andreassen OA, Ferrante RJ, Klivenyi P, Klein AM, Shinobu LA, Epstein CJ, Beal MF. Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis. Annals of Neurology. 47: 447-55. PMID 10762155 DOI: 10.1002/1531-8249(200004)47:4<447::AID-ANA7>3.0.CO;2-R  1
2000 Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 4386-91. PMID 10737773 DOI: 10.1073/pnas.080499597  1
2000 Huang TT, Carlson EJ, Gillespie AM, Shi Y, Epstein CJ. Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 55: B5-9. PMID 10719757  1
1999 Huang TT, Carlson EJ, Raineri I, Gillespie AM, Kozy H, Epstein CJ. The use of transgenic and mutant mice to study oxygen free radical metabolism. Annals of the New York Academy of Sciences. 893: 95-112. PMID 10672232  1
1999 Siarey RJ, Carlson EJ, Epstein CJ, Balbo A, Rapoport SI, Galdzicki Z. Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. Neuropharmacology. 38: 1917-20. PMID 10608287 DOI: 10.1016/S0028-3908(99)00083-0  1
1999 Li Y, Carlson E, Murakami K, Copin JC, Luche R, Chen SF, Epstein CJ, Chan PH. Targeted expression of human CuZn superoxide dismutase gene in mouse central nervous system. Journal of Neuroscience Methods. 89: 49-55. PMID 10476683 DOI: 10.1016/S0165-0270(99)00037-0  1
1999 Rando TA, Epstein CJ. Copper/zinc superoxide dismutase: more is not necessarily better! Annals of Neurology. 46: 135-6. PMID 10401795  1
1999 Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. The Journal of Biological Chemistry. 274: 20071-4. PMID 10400615 DOI: 10.1074/jbc.274.29.20071  1
1999 Fujimura M, Morita-Fujimura Y, Kawase M, Copin JC, Calagui B, Epstein CJ, Chan PH. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3414-22. PMID 10212301  1
1999 Grasbon T, Grasbon-Frodl EM, Juliusson B, Epstein C, Brundin P, Kampik A, Ehinger B. CuZn superoxide dismutase transgenic retinal transplants. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 237: 336-41. PMID 10208267 DOI: 10.1007/s004170050241  1
1999 Kamii H, Kato I, Kinouchi H, Chan PH, Epstein CJ, Akabane A, Okamoto H, Yoshimoto T. Amelioration of vasospasm after subarachnoid hemorrhage in transgenic mice overexpressing CuZn-superoxide dismutase. Stroke; a Journal of Cerebral Circulation. 30: 867-71; discussion 8. PMID 10187893  1
1999 Gum JR, Hicks JW, Gillespie AM, Carlson EJ, Kömüves L, Karnik S, Hong JC, Epstein CJ, Kim YS. Goblet cell-specific expression mediated by the MUC2 mucin gene promoter in the intestine of transgenic mice. The American Journal of Physiology. 276: G666-76. PMID 10070043  1
1999 Van Remmen H, Salvador C, Yang H, Huang TT, Epstein CJ, Richardson A. Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Archives of Biochemistry and Biophysics. 363: 91-7. PMID 10049502 DOI: 10.1006/abbi.1998.1060  1
1999 Melov S, Coskun P, Patel M, Tuinstra R, Cottrell B, Jun AS, Zastawny TH, Dizdaroglu M, Goodman SI, Huang TT, Miziorko H, Epstein CJ, Wallace DC. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 846-51. PMID 9927656 DOI: 10.1073/pnas.96.3.846  1
1998 Huang TT, Carlson EJ, Gillespie AM, Epstein CJ. Genetic modification of the dilated cardiomyopathy and neonatal lethality phenotype of mice lacking manganese superoxide dismutase. Age. 21: 83-4. PMID 23604356 DOI: 10.1007/s11357-998-0011-y  1
1998 Kinouchi H, Kamii H, Mikawa S, Epstein CJ, Yoshimoto T, Chan PH. Role of superoxide dismutase in ischemic brain injury: a study using SOD-1 transgenic mice. Cellular and Molecular Neurobiology. 18: 609-20. PMID 9876869 DOI: 10.1023/A:1020213717336  1
1998 Li Y, Copin JC, Reola LF, Calagui B, Gobbel GT, Chen SF, Sato S, Epstein CJ, Chan PH. Reduced mitochondrial manganese-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons. Brain Research. 814: 164-70. PMID 9838093 DOI: 10.1016/S0006-8993(98)01082-8  1
1998 Williams MD, Van Remmen H, Conrad CC, Huang TT, Epstein CJ, Richardson A. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. The Journal of Biological Chemistry. 273: 28510-5. PMID 9774481 DOI: 10.1074/jbc.273.43.28510  1
1998 Chan PH, Kawase M, Murakami K, Chen SF, Li Y, Calagui B, Reola L, Carlson E, Epstein CJ. Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8292-9. PMID 9763473  1
1998 Horie Y, Wolf R, Flores SC, McCord JM, Epstein CJ, Granger DN. Transgenic mice with increased copper/zinc-superoxide dismutase activity are resistant to hepatic leukostasis and capillary no-reflow after gut ischemia/reperfusion. Circulation Research. 83: 691-6. PMID 9758638  1
1998 Rando TA, Crowley RS, Carlson EJ, Epstein CJ, Mohapatra PK. Overexpression of copper/zinc superoxide dismutase: a novel cause of murine muscular dystrophy. Annals of Neurology. 44: 381-6. PMID 9749606 DOI: 10.1002/ana.410440315  1
1998 Fullerton HJ, Ditelberg JS, Chen SF, Sarco DP, Chan PH, Epstein CJ, Ferriero DM. Copper/zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia. Annals of Neurology. 44: 357-64. PMID 9749602 DOI: 10.1002/ana.410440311  1
1998 Cardozo-Pelaez F, Song S, Parthasarathy A, Epstein CJ, Sanchez-Ramos J. Attenuation of age-dependent oxidative damage to DNA and protein in brainstem of Tg Cu/Zn SOD mice. Neurobiology of Aging. 19: 311-6. PMID 9733163 DOI: 10.1016/S0197-4580(98)00067-0  1
1998 Tsan MF, White JE, Caska B, Epstein CJ, Lee CY. Susceptibility of heterozygous MnSOD gene-knockout mice to oxygen toxicity. American Journal of Respiratory Cell and Molecular Biology. 19: 114-20. PMID 9651187 DOI: 10.1165/ajrcmb.19.1.3066  1
1998 Sago H, Carlson EJ, Smith DJ, Kilbridge J, Rubin EM, Mobley WC, Epstein CJ, Huang TT. Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities. Proceedings of the National Academy of Sciences of the United States of America. 95: 6256-61. PMID 9600952 DOI: 10.1073/pnas.95.11.6256  1
1998 Cao YQ, Mantyh PW, Carlson EJ, Gillespie AM, Epstein CJ, Basbaum AI. Primary afferent tachykinins are required to experience moderate to intense pain. Nature. 392: 390-4. PMID 9537322 DOI: 10.1038/32897  1
1998 Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. The Journal of Biological Chemistry. 273: 4296-9. PMID 9468475 DOI: 10.1074/jbc.273.8.4296  1
1997 Eppihimer MJ, Russell J, Anderson DC, Epstein CJ, Laroux S, Granger DN. Modulation of P-selectin expression in the postischemic intestinal microvasculature. The American Journal of Physiology. 273: G1326-32. PMID 9435558  1
1997 Kondo T, Reaume AG, Huang TT, Murakami K, Carlson E, Chen S, Scott RW, Epstein CJ, Chan PH. Edema formation exacerbates neurological and histological outcomes after focal cerebral ischemia in CuZn-superoxide dismutase gene knockout mutant mice. Acta Neurochirurgica. Supplement. 70: 62-4. PMID 9416279  1
1997 Tribble DL, Gong EL, Leeuwenburgh C, Heinecke JW, Carlson EL, Verstuyft JG, Epstein CJ. Fatty streak formation in fat-fed mice expressing human copper-zinc superoxide dismutase. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1734-40. PMID 9327771  1
1997 Murakami K, Kondo T, Epstein CJ, Chan PH. Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice. Stroke; a Journal of Cerebral Circulation. 28: 1797-804. PMID 9303028  1
1997 Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. The Journal of Clinical Investigation. 100: 957-62. PMID 9276712 DOI: 10.1172/JCI231  1
1997 Huang TT, Yasunami M, Carlson EJ, Gillespie AM, Reaume AG, Hoffman EK, Chan PH, Scott RW, Epstein CJ. Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Archives of Biochemistry and Biophysics. 344: 424-32. PMID 9264557 DOI: 10.1006/abbi.1997.0237  1
1997 Mena MA, Khan U, Togasaki DM, Sulzer D, Epstein CJ, Przedborski S. Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture. Journal of Neurochemistry. 69: 21-33. PMID 9202290  1
1997 Kondo T, Reaume AG, Huang TT, Carlson E, Murakami K, Chen SF, Hoffman EK, Scott RW, Epstein CJ, Chan PH. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4180-9. PMID 9151735  1
1997 Kikuchi Y, Shimosegawa T, Moriizumi S, Kimura K, Satoh A, Koizumi M, Kato I, Epstein CJ, Toyota T. Transgenic copper/zinc-superoxide dismutase ameliorates caerulein-induced pancreatitis in mice. Biochemical and Biophysical Research Communications. 233: 177-81. PMID 9144418 DOI: 10.1006/bbrc.1997.6421  1
1997 Kostic V, Gurney ME, Deng HX, Siddique T, Epstein CJ, Przedborski S. Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Annals of Neurology. 41: 497-504. PMID 9124807 DOI: 10.1002/ana.410410413  1
1997 Kondo T, Sharp FR, Honkaniemi J, Mikawa S, Epstein CJ, Chan PH. DNA fragmentation and Prolonged expression of c-fos, c-jun, and hsp70 in kainic acid-induced neuronal cell death in transgenic mice overexpressing human CuZn-superoxide dismutase. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 241-56. PMID 9119897 DOI: 10.1097/00004647-199703000-00001  1
1997 Luche RM, Maiwald R, Carlson EJ, Epstein CJ. Novel mutations in an otherwise strictly conserved domain of CuZn superoxide dismutase. Molecular and Cellular Biochemistry. 168: 191-4. PMID 9062909 DOI: 10.1023/A:1006871524623  1
1997 Yu CE, Oshima J, Wijsman EM, Nakura J, Miki T, Piussan C, Matthews S, Fu YH, Mulligan J, Martin GM, Schellenberg GD. Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group. American Journal of Human Genetics. 60: 330-41. PMID 9012406  1
1997 Epstein CJ. 1996 ASHG Presidential Address. Toward the 21st century. American Journal of Human Genetics. 60: 1-9. PMID 8981939  1
1997 Sanchez-Ramos JR, Song S, Facca A, Basit A, Epstein CJ. Transgenic murine dopaminergic neurons expressing human Cu/Zn superoxide dismutase exhibit increased density in culture, but no resistance to methylphenylpyridinium-induced degeneration. Journal of Neurochemistry. 68: 58-67. PMID 8978710  1
1996 Elmer GI, Evans JL, Goldberg SR, Epstein CJ, Cadet JL. Transgenic superoxide dismutase mice: Increased mesolimbic µ-opioid receptors results in greater opioid-induced stimulation and opioid-reinforced behavior. Behavioural Pharmacology. 7: 628-639. PMID 11224459  1
1996 Epstein CJ, Motulsky AG. Werner syndrome: entering the helicase era. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 1025-7. PMID 8976161 DOI: 10.1002/bies.950181214  1
1996 Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, Murphy DL. Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals. Molecular Pharmacology. 50: 1511-9. PMID 8967972  1
1996 Raber J, Toggas SM, Lee S, Bloom FE, Epstein CJ, Mucke L. Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase. Virology. 226: 362-73. PMID 8955056 DOI: 10.1006/viro.1996.0664  1
1996 Kondo T, Murakami K, Honkaniemi J, Sharp FR, Epstein CJ, Chan PH. Expression of hsp70 mRNA is induced in the brain of transgenic mice overexpressing human CuZn-superoxide dismutase following transient global cerebral ischemia. Brain Research. 737: 321-6. PMID 8930384 DOI: 10.1016/0006-8993(96)00949-3  1
1996 Holtzman DM, Santucci D, Kilbridge J, Chua-Couzens J, Fontana DJ, Daniels SE, Johnson RM, Chen K, Sun Y, Carlson E, Alleva E, Epstein CJ, Mobley WC. Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 93: 13333-8. PMID 8917591 DOI: 10.1073/pnas.93.23.13333  1
1996 Kamii H, Mikawa S, Murakami K, Kinouchi H, Yoshimoto T, Reola L, Carlson E, Epstein CJ, Chan PH. Effects of nitric oxide synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 16: 1153-7. PMID 8898687 DOI: 10.1097/00004647-199611000-00009  1
1996 Mikawa S, Kinouchi H, Kamii H, Gobbel GT, Chen SF, Carlson E, Epstein CJ, Chan PH. Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice. Journal of Neurosurgery. 85: 885-91. PMID 8893728 DOI: 10.3171/jns.1996.85.5.0885  1
1996 Przedborski S, Khan U, Kostic V, Carlson E, Epstein CJ, Sulzer D. Increased superoxide dismutase activity improves survival of cultured postnatal midbrain neurons. Journal of Neurochemistry. 67: 1383-92. PMID 8858919  1
1996 Imaizumi S, Kondo T, Deli MA, Gobbel G, Joó F, Epstein CJ, Yoshimoto T, Chan PH. The influence of oxygen free radicals on the permeability of the monolayer of cultured brain endothelial cells. Neurochemistry International. 29: 205-11. PMID 8837050 DOI: 10.1016/0197-0186(95)00120-4  1
1996 Ditelberg JS, Sheldon RA, Epstein CJ, Ferriero DM. Brain injury after perinatal hypoxia-ischemia is exacerbated in copper/zinc superoxide dismutase transgenic mice. Pediatric Research. 39: 204-8. PMID 8825788 DOI: 10.1203/00006450-199604001-01234  1
1996 Copin JC, Reola LF, Chan TY, Li Y, Epstein CJ, Chan PH. Oxygen deprivation but not a combination of oxygen, glucose, and serum deprivation induces DNA degradation in mouse cortical neurons in vitro: attenuation by transgenic overexpression of CuZn-superoxide dismutase. Journal of Neurotrauma. 13: 233-44. PMID 8797173  1
1996 Chan PH, Epstein CJ, Kinouchi H, Kamii H, Chen SF, Carlson E, Gafni J, Yang G, Reola L. Neuroprotective role of CuZn-superoxide dismutase in ischemic brain damage. Advances in Neurology. 71: 271-280. PMID 8790805  1
1996 Epstein CJ, Strass E. ASHG report: Statement on informed consent for genetic research American Journal of Human Genetics. 59: 471-474. PMID 8755936  1
1996 Klaeger C, de Sa L, Klaeger AJ, Carlson EJ, Good WV, Epstein CJ. An elevated level of copper zinc superoxide dismutase fails to prevent oxygen induced retinopathy in mice. The British Journal of Ophthalmology. 80: 429-34. PMID 8695565  1
1996 Maiwald R, Luche RM, Epstein CJ. Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 628. PMID 8679003  1
1996 Goddard KA, Yu CE, Oshima J, Miki T, Nakura J, Piussan C, Martin GM, Schellenberg GD, Wijsman EM. Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers. American Journal of Human Genetics. 58: 1286-302. PMID 8651307  1
1996 Raineri I, Huang TT, Epstein CJ, Epstein LB. Antisense manganese superoxide dismutase mRNA inhibits the antiviral action of interferon-gamma and interferon-alpha. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 16: 61-8. PMID 8640453  1
1996 Holtzman DM, Epstein CJ, Mobley WC. The human trisomy 21 brain: Insights from mouse models of Down syndrome Mental Retardation and Developmental Disabilities Research Reviews. 2: 66-72.  1
1996 Rosenberg MD, Sheldon RA, Epstein CJ, Ferriero DM. Nitric oxide inhibition does not protect the superoxide dismutase transgenic mouse pup brain from hypoxic-ischemic injury Journal of Investigative Medicine. 44: 135A.  1
1995 Mikawa S, Sharp FR, Kamii H, Kinouchi H, Epstein CJ, Chan PK. Expression of c-fos and hsp70 mRNA after traumatic brain injury in transgenic mice overexpressing CuZn-superoxide dismutase. Brain Research. Molecular Brain Research. 33: 288-94. PMID 8750888 DOI: 10.1016/0169-328X(95)00146-J  1
1995 Chan PH, Epstein CJ, Li Y, Huang TT, Carlson E, Kinouchi H, Yang G, Kamii H, Mikawa S, Kondo T. Transgenic mice and knockout mutants in the study of oxidative stress in brain injury. Journal of Neurotrauma. 12: 815-24. PMID 8594209  1
1995 Cadet JL, Ali SF, Rothman RB, Epstein CJ. Neurotoxicity, drugs and abuse, and the CuZn-superoxide dismutase transgenic mice. Molecular Neurobiology. 11: 155-63. PMID 8561959 DOI: 10.1007/BF02740692  1
1995 Epstein CJ. Epilogue: toward the twenty-first century with Down syndrome--a personal view of how far we have come and of how far we can reasonably expect to go. Progress in Clinical and Biological Research. 393: 241-6. PMID 8545454  1
1995 Holtzman DM, Kilbridge J, Chen KS, Rabin J, Luche R, Carlson E, Epstein CJ, Mobley WC. Preliminary characterization of the central nervous system in partial trisomy 16 mice. Progress in Clinical and Biological Research. 393: 227-40. PMID 8545453  1
1995 de Vos S, Epstein CJ, Carlson E, Cho SK, Koeffler HP. Transgenic mice overexpressing human copper/zinc-superoxide dismutase (Cu/Zn SOD) are not resistant to endotoxic shock. Biochemical and Biophysical Research Communications. 208: 523-31. PMID 7695603 DOI: 10.1006/bbrc.1995.1370  1
1995 Beal MF, Ferrante RJ, Henshaw R, Matthews RT, Chan PH, Kowall NW, Epstein CJ, Schulz JB. 3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice. Journal of Neurochemistry. 65: 919-22. PMID 7616254  1
1995 Nakao N, Frodl EM, Widner H, Carlson E, Eggerding FA, Epstein CJ, Brundin P. Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nature Medicine. 1: 226-31. PMID 7585038 DOI: 10.1038/nm0395-226  1
1995 Epstein CJ. The new dysmorphology: application of insights from basic developmental biology to the understanding of human birth defects. Proceedings of the National Academy of Sciences of the United States of America. 92: 8566-73. PMID 7567976 DOI: 10.1073/pnas.92.19.8566  1
1995 Cerruti C, Sheng P, Ladenheim B, Epstein CJ, Cadet JL. Involvement of oxidative and L-arginine-NO pathways in the neurotoxicity of drugs of abuse in vitro. Clinical and Experimental Pharmacology & Physiology. 22: 381-2. PMID 7554438  1
1995 Elmer GI, Evans JL, Ladenheim B, Epstein CJ, Cadet JL. Transgenic superoxide dismutase mice differ in opioid-induced analgesia. European Journal of Pharmacology. 283: 227-32. PMID 7498314 DOI: 10.1016/0014-2999(95)00365-R  1
1995 Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH, Wallace DC, Epstein CJ. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nature Genetics. 11: 376-81. PMID 7493016 DOI: 10.1038/ng1295-376  1
1994 Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein P, Epstein CJ, Kamii H. Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 25: 165-70. PMID 8266365  1
1994 Miller MW, Duhl DM, Winkes BM, Arredondo-Vega F, Saxon PJ, Wolff GL, Epstein CJ, Hershfield MS, Barsh GS. The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene. The Embo Journal. 13: 1806-16. PMID 8168479  1
1994 Kamii H, Kinouchi H, Sharp FR, Koistinaho J, Epstein CJ, Chan PH. Prolonged expression of hsp70 mRNA following transient focal cerebral ischemia in transgenic mice overexpressing CuZn-superoxide dismutase. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 478-86. PMID 8163590 DOI: 10.1038/jcbfm.1994.59  1
1994 Kujirai K, Carlson E, Epstein CJ, Cadet JL. Autoradiographic distribution of mu opioid receptors in the brains of Cu/Zn-superoxide dismutase mice. Synapse (New York, N.Y.). 17: 76-83. PMID 8091304 DOI: 10.1002/syn.890170203  1
1994 Duhl DM, Stevens ME, Vrieling H, Saxon PJ, Miller MW, Epstein CJ, Barsh GS. Pleiotropic effects of the mouse lethal yellow (Ay) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs. Development (Cambridge, England). 120: 1695-708. PMID 8050375  1
1994 Shi YP, Huang TT, Carlson EJ, Epstein CJ. The mapping of transgenes by fluorescence in situ hybridization on G-banded mouse chromosomes. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 337-41. PMID 8043947 DOI: 10.1007/BF00356551  1
1994 Sakashita A, Epstein CJ, Carlson E, Koeffler HP. Hematopoietic progenitor cells of transgenic mice with increased copper/zinc-superoxide dismutase activity are resistant to tumor necrosis factor. Journal of Cellular Physiology. 160: 233-8. PMID 8040183 DOI: 10.1002/jcp.1041600204  1
1994 Kubisch HM, Wang J, Luche R, Carlson E, Bray TM, Epstein CJ, Phillips JP. Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes. Proceedings of the National Academy of Sciences of the United States of America. 91: 9956-9. PMID 7937925 DOI: 10.1073/pnas.91.21.9956  1
1994 Eggerding FA, Schonberg SA, Chehab FF, Norton ME, Cox VA, Epstein CJ. Uniparental isodisomy for paternal 7p and maternal 7q in a child with growth retardation. American Journal of Human Genetics. 55: 253-65. PMID 7913578  1
1994 Kondo T, Imaizumi S, Kato I, Deli MA, Jóo F, Chan PH, Epstein CJ, Yoshimoto T. [Effect of free radicals on the permeability of the blood brain barrier--using in vitro blood brain barrier model of human-SOD transgenic mouse]. Nō to Shinkei = Brain and Nerve. 46: 1155-61. PMID 7893533  1
1994 Kamii H, Kinouchi H, Sharp FR, Epstein CJ, Sagar SM, Chan PH. Expression of c-fos mRNA after a mild focal cerebral ischemia in SOD-1 transgenic mice. Brain Research. 662: 240-4. PMID 7859076 DOI: 10.1016/0006-8993(94)90818-4  1
1994 Nakura J, Wijsman EM, Miki T, Kamino K, Yu CE, Oshima J, Fukuchi Ki, Weber JL, Piussan C, Melaragno MI, Epstein CJ, Scappaticci S, Fraccaro M, Matsumura T, Murano S, et al. Homozygosity Mapping of the Werner Syndrome Locus (WRN) Genomics. 23: 600-608. PMID 7851888 DOI: 10.1006/geno.1994.1548  1
1994 Fiedler JL, Epstein CJ, Rapoport SI, Caviedes R, Caviedes P. Regional alteration of cholinergic function in central neurons of trisomy 16 mouse fetuses, an animal model of human trisomy 21 (Down syndrome). Brain Research. 658: 27-32. PMID 7834352  1
1994 Chan PH, Epstein CJ, Kinouchi H, Kamii H, Imaizumi S, Yang G, Chen SF, Gafni J, Carlson E. SOD-1 transgenic mice as a model for studies of neuroprotection in stroke and brain trauma. Annals of the New York Academy of Sciences. 738: 93-103. PMID 7832461  1
1994 Walters L, Areen J, Brewer MF, Capron A, Childress JF, Epstein CJ, Erickson RP, Gellert MF, Kelley WN, Leventhal BG, McIvor RS, Meyers AS, Miller DA, Murray RF, Neiman PE, et al. Minutes of the Human Gene Therapy Subcommittee meeting, November 21-22, 1991 Human Gene Therapy. 5: 229-262.  1
1993 Cadet JL, Kujirai K, Carlson E, Epstein CJ. Autoradiographic distribution of [3H]neurotensin receptors in the brains of superoxide dismutase transgenic mice. Synapse (New York, N.Y.). 14: 24-33. PMID 8390106 DOI: 10.1002/syn.890140105  1
1993 Chan PH, Kinouchi H, Epstein CJ, Carlson E, Chen SF, Imaizumi S, Yang GY. Role of superoxide dismutase in ischemic brain injury: reduction of edema and infarction in transgenic mice following focal cerebral ischemia. Progress in Brain Research. 96: 97-104. PMID 8332750  1
1993 Chan PH, Kamii H, Yang G, Gafni J, Epstein CJ, Carlson E, Reola L. Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia. Neuroreport. 5: 293-6. PMID 8298091  1
1993 Holtzman DM, Li Y, Chen K, Gage FH, Epstein CJ, Mobley WC. Nerve growth factor reverses neuronal atrophy in a Down syndrome model of age-related neurodegeneration. Neurology. 43: 2668-73. PMID 8255474  1
1993 Epstein CJ. Seven momentous years. American Journal of Human Genetics. 53: 1163-6. PMID 8250037  1
1993 Epstein CJ. The conceptual bases for the phenotypic mapping of conditions resulting from aneuploidy. Progress in Clinical and Biological Research. 384: 1-18. PMID 8115397  1
1992 Holtzman DM, Li YW, DeArmond SJ, McKinley MP, Gage FH, Epstein CJ, Mobley WC. Mouse model of neurodegeneration: atrophy of basal forebrain cholinergic neurons in trisomy 16 transplants. Proceedings of the National Academy of Sciences of the United States of America. 89: 1383-7. PMID 1741393  1
1992 Huang TT, Carlson EJ, Leadon SA, Epstein CJ. Relationship of resistance to oxygen free radicals to CuZn-superoxide dismutase activity in transgenic, transfected, and trisomic cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 903-10. PMID 1740238  1
1992 Epstein CJ. Organized medical genetics at a crossroad. American Journal of Human Genetics. 51: 231-4. PMID 1642225  1
1992 Przedborski S, Kostic V, Jackson-Lewis V, Naini AB, Simonetti S, Fahn S, Carlson E, Epstein CJ, Cadet JL. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 1658-67. PMID 1578260  1
1992 Przedborski S, Jackson-Lewis V, Kostic V, Carlson E, Epstein CJ, Cadet JL. Superoxide dismutase, catalase, and glutathione peroxidase activities in copper/zinc-superoxide dismutase transgenic mice. Journal of Neurochemistry. 58: 1760-7. PMID 1560230  1
1992 Holtzman DM, Epstein CJ. The molecular genetics of Down syndrome. Molecular Genetic Medicine. 2: 105-20. PMID 1458222  1
1992 Berger CN, Epstein CJ. Deficient transformation of murine trisomy 16 fetal liver cells by the Abelson and J2 viruses. Immunology Letters. 33: 47-51. PMID 1427990 DOI: 10.1016/0165-2478(92)90092-3  1
1992 Bredesen DE, Kane DJ, Holtzman DM, Epstein CJ. Preliminary characterization of long-term reaggregating cultures of trisomy 16 central nervous system. Progress in Clinical and Biological Research. 379: 259-70. PMID 1409749  1
1992 Holtzman DM, Li Y, Gage FH, Epstein CJ, Mobley WC. Neurodegeneration and gene dysregulation: studies utilizing the mouse trisomy 16 model of Down syndrome. Progress in Clinical and Biological Research. 379: 227-44. PMID 1409747  1
1992 Holtzman DM, Bayney RM, Li YW, Khosrovi H, Berger CN, Epstein CJ, Mobley WC. Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome. The Embo Journal. 11: 619-27. PMID 1371464  1
1992 Huang TT, Carlson EJ, Epstein LB, Epstein CJ. The role of superoxide anions in the establishment of an interferon-alpha-mediated antiviral state. Free Radical Research Communications. 17: 59-72. PMID 1332917 DOI: 10.3109/10715769209061089  1
1991 Korenberg JR, Kalousek DK, Anneren G, Pulst SM, Hall JG, Epstein CJ, Cox DR. Deletion of chromosome 21 and normal intelligence: molecular definition of the lesion. Human Genetics. 87: 112-8. PMID 2066097 DOI: 10.1007/BF00204163  1
1991 Epstein CJ, Foster DB, DeArmond SJ, Prusiner SB. Acceleration of scrapie in trisomy 16----diploid aggregation chimeras. Annals of Neurology. 29: 95-7. PMID 1996884 DOI: 10.1002/ana.410290117  1
1991 Przedborski S, Kostic V, Jackson-Lewis V, Carlson E, Epstein CJ, Cadet JL. Quantitative autoradiographic distribution of [3H]-MPTP binding in the brains of superoxide dismutase transgenic mice. Brain Research Bulletin. 26: 987-91. PMID 1933417 DOI: 10.1016/0361-9230(91)90267-N  1
1991 Epstein CJ. The forensic applications of molecular genetics--the journal's responsibility. American Journal of Human Genetics. 49: 697-8. PMID 1897519  1
1991 Chan PH, Yang GY, Chen SF, Carlson E, Epstein CJ. Cold-induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn-superoxide dismutase. Annals of Neurology. 29: 482-6. PMID 1859179 DOI: 10.1002/ana.410290506  1
1991 Holtzman DM, Li YW, Gage FH, DeArmond SJ, Epstein CJ, McKinley MP, Mobley WC. Modeling cholinergic abnormalities in Down syndrome and Alzheimer's disease. Progress in Clinical and Biological Research. 373: 189-202. PMID 1838184  1
1991 Epstein CJ. Aneuploidy and morphogenesis. Progress in Clinical and Biological Research. 373: 1-18. PMID 1838180  1
1991 Epstein CJ, Korenberg JR, Annerén G, Antonarakis SE, Aymé S, Courchesne E, Epstein LB, Fowler A, Groner Y, Huret JL. Protocols to establish genotype-phenotype correlations in Down syndrome. American Journal of Human Genetics. 49: 207-35. PMID 1829580  1
1991 Kinouchi H, Epstein CJ, Mizui T, Carlson E, Chen SF, Chan PH. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 88: 11158-62. PMID 1763030  1
1991 Epstein CJ. Editorial: The forensic applications of molecular genetics - The Journal's responsibilities American Journal of Human Genetics. 49: 697-698.  1
1990 Barsh GS, Lovett M, Epstein CJ. Effects of the lethal yellow (Ay) mutation in mouse aggregation chimeras. Development (Cambridge, England). 109: 683-90. PMID 2401219  1
1990 Epstein CJ. The consequences of chromosome imbalance. American Journal of Medical Genetics. Supplement. 7: 31-7. PMID 2149968  1
1990 Epstein CJ, Berger CN, Carlson EJ, Chan PH, Huang TT. Models for Down syndrome: chromosome 21-specific genes in mice. Progress in Clinical and Biological Research. 360: 215-32. PMID 2147287  1
1990 Chan PH, Chu L, Chen SF, Carlson EJ, Epstein CJ. Attenuation of glutamate-induced neuronal swelling and toxicity in transgenic mice overexpressing human CuZn-superoxide dismutase. Acta Neurochirurgica. Supplementum. 51: 245-7. PMID 1982480  1
1989 Barsh GS, Epstein CJ. The long-range restriction map surrounding the mouse agouti locus reveals a disparity between physical and genetic distances. Genomics. 5: 9-18. PMID 2570033 DOI: 10.1016/0888-7543(89)90080-3  1
1989 Barsh GS, Epstein CJ. Physical and genetic characterization of a 75-kilobase deletion associated with al, a recessive lethal allele at the mouse agouti locus. Genetics. 121: 811-8. PMID 2566558  1
1988 Epstein CJ, Seto S, Golabi M. Chance vs. causality in the association of Down syndrome and holoprosencephaly. American Journal of Medical Genetics. 30: 939-42. PMID 2973235 DOI: 10.1002/ajmg.1320300410  1
1987 Lovett M, Goldgaber D, Ashley P, Cox DR, Gajdusek DC, Epstein CJ. The mouse homolog of the human amyloid beta protein (AD-AP) gene is located on the distal end of mouse chromosome 16: further extension of the homology between human chromosome 21 and mouse chromosome 16. Biochemical and Biophysical Research Communications. 144: 1069-75. PMID 3555492 DOI: 10.1016/S0006-291X(87)80073-6  1
1987 Epstein CJ, Avraham KB, Lovett M, Smith S, Elroy-Stein O, Rotman G, Bry C, Groner Y. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 84: 8044-8. PMID 2960971  1
1987 Orozco CB, Smith SA, Epstein CJ, Rapoport SI. Electrophysiological properties of cultured dorsal root ganglion and spinal cord neurons of normal and trisomy 16 fetal mice. Brain Research. 429: 111-22. PMID 2952222  0.32
1987 Lovett M, Cheng ZY, Lamela EM, Yokoi T, Epstein CJ. Molecular markers for the agouti coat color locus of the mouse. Genetics. 115: 747-54. PMID 2884164  0.52
1987 Lovett M, Epstein CJ. The lethal yellow allele-associated provirus results in the production of chimeric viral-host RNAs. Proceedings of the National Academy of Sciences of the United States of America. 84: 2853-7. PMID 2437585  0.52
1986 Cheng ZY, Lovett M, Epstein LB, Epstein CJ. The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization. Cytogenetics and Cell Genetics. 41: 101-6. PMID 3456887  0.52
1986 Yokoi T, Lovett M, Cheng ZY, Epstein CJ. Isolation of transcribed DNA sequences from chromosome 21 using mouse fetal cDNA. Human Genetics. 74: 137-42. PMID 3021606  0.52
1985 Magnuson T, Debrot S, Dimpfl J, Zweig A, Zamora T, Epstein CJ. The early lethality of autosomal monosomy in the mouse. The Journal of Experimental Zoology. 236: 353-60. PMID 4086989 DOI: 10.1002/jez.1402360313  0.4
1985 Epstein CJ, Hofmeister BG, Yee D, Smith SA, Philip R, Cox DR, Epstein LB. Stem cell deficiencies and thymic abnormalities in fetal mouse trisomy 16. The Journal of Experimental Medicine. 162: 695-712. PMID 3160808  0.32
1985 Cox DR, Epstein CJ. Comparative gene mapping of human chromosome 21 and mouse chromosome 16. Annals of the New York Academy of Sciences. 450: 169-77. PMID 3160288  0.32
1985 Epstein CJ, Cox DR, Epstein LB. Mouse trisomy 16: an animal model of human trisomy 21 (Down syndrome). Annals of the New York Academy of Sciences. 450: 157-68. PMID 3160287  0.32
1984 Lovett M, Cox DR, Yee D, Boll W, Weissmann C, Epstein CJ, Epstein LB. The chromosomal location of mouse interferon alpha genes. The Embo Journal. 3: 1643-6. PMID 6745245  1
1984 Cox DR, Smith SA, Epstein LB, Epstein CJ. Mouse trisomy 16 as an animal model of human trisomy 21 (Down syndrome): production of viable trisomy 16 diploid mouse chimeras. Developmental Biology. 101: 416-24. PMID 6229437  0.32
1984 Magnuson T, Epstein CJ. Oligosyndactyly: a lethal mutation in the mouse that results in mitotic arrest very early in development. Cell. 38: 823-33. PMID 6091901  0.4
1983 Epstein CJ, Cox DR, Schonberg SA, Hogge WA. Recent developments in the prenatal diagnosis of genetic diseases and birth defects. Annual Review of Genetics. 17: 49-83. PMID 6364964 DOI: 10.1146/annurev.ge.17.120183.000405  0.32
1983 Weil J, Epstein CJ, Epstein LB, van Blerkom J, Xuong NH. Computer-assisted analysis demonstrates that polypeptides induced by natural and recombinant human interferon-alpha are the same and that some have related primary structures. Antiviral Research. 3: 303-14. PMID 6230991 DOI: 10.1016/0166-3542(83)90038-4  1
1982 Magnuson T, Smith S, Epstein CJ. The development of monosomy 19 mouse embryos. Journal of Embryology and Experimental Morphology. 69: 223-36. PMID 7119668  0.52
1982 Magnuson T, Epstein CJ, Silver LM, Martin GR. Pluripotent embryonic stem cell lines can be derived from tw5/tw5 blastocysts. Nature. 298: 750-3. PMID 7110310 DOI: 10.1038/298750a0  0.52
1982 Epstein CJ, Smith SA, Zamora T, Sawicki JA, Magnuson TR, Cox DR. Production of viable adult trisomy 17 reversible diploid mouse chimeras. Proceedings of the National Academy of Sciences of the United States of America. 79: 4376-80. PMID 6956868 DOI: 10.1073/pnas.79.14.4376  1
1982 Epstein CJ, Magnuson T. Genetic control of early mammalian development. Progress in Clinical and Biological Research. 103: 327-38. PMID 6761691  0.4
1982 Epstein CJ, Epstein LB, Weil J, Cox DR. Trisomy 21: mechanisms and models. Annals of the New York Academy of Sciences. 396: 107-18. PMID 6185031  0.32
1982 Epstein CJ, McManus NH, Epstein LB, Branca AA, D'Alessandro SB, Baglioni C. Direct evidence that the gene product of the human chromosome 21 locus, IFRC, is the interferon-alpha receptor. Biochemical and Biophysical Research Communications. 107: 1060-6. PMID 6182879 DOI: 10.1016/0006-291X(82)90629-5  1
1982 Cox DR, Sawicki JA, Yee D, Appella E, Epstein CJ. Assignment of the gene for beta 2-microglobulin (B2m) to mouse chromosome 2. Proceedings of the National Academy of Sciences of the United States of America. 79: 1930-4. PMID 6177004  0.32
1981 Cox DR, Francke U, Epstein CJ. Assignment of genes to the human X chromosome by the two-dimensional electrophoretic analysis of total cell proteins from rodent-human somatic cell hybrids. American Journal of Human Genetics. 33: 495-512. PMID 7196152  0.32
1981 Magnuson T, Epstein CJ. Genetic control of very early mammalian development. Biological Reviews of the Cambridge Philosophical Society. 56: 369-408. PMID 7030419  0.4
1981 Magnuson T, Epstein CJ. Characterization of concanavalin A precipitated proteins from early mouse embryos: a 2-dimensional gel electrophoresis study. Developmental Biology. 81: 193-9. PMID 6893973  0.4
1981 Epstein CJ, Epstein LB, Cox DR, Weil J. Functional implications of gene dosage effects in trisomy 21. Human Genetics. Supplement. 2: 155-72. PMID 6185454  0.32
1981 Sawicki JA, Magnuson T, Epstein CJ. Evidence for expression of the paternal genome in the two-cell mouse embryo. Nature. 294: 450-1. PMID 6171732  0.4
1981 Sawicki JA, Epstein CJ. H-2 antigens as genetic markers: a two-dimensional gel electrophoretic study. Immunogenetics. 12: 141-51. PMID 6162790 DOI: 10.1007/BF01561657  1
1980 Epstein CJ, Smith S, Travis B. Expression of H-Y antigen on preimplantation mouse embryos. Tissue Antigens. 15: 63-7. PMID 12735334  1
1980 Stephens JD, Golbus MS, Miller TR, Wilber RR, Epstein CJ. Multiple congenital anomalies in a fetus exposed to 5-fluorouracil during the first trimester. American Journal of Obstetrics and Gynecology. 137: 747-9. PMID 7395946  1
1980 Bartley JA, Epstein CJ. Gene dosage effect for glycinamide ribonucleotide synthetase in human fibroblasts trisomic for chromosome 21. Biochemical and Biophysical Research Communications. 93: 1286-9. PMID 6446912 DOI: 10.1016/0006-291X(80)90629-4  1
1980 Epstein LB, Cox DR, Epstein CJ. Assignment of the genes for sensitivity to interferon [IfRec] and soluble superoxide dismutase [SOD-1] to mouse chromosome. Annals of the New York Academy of Sciences. 350: 171-3. PMID 6165271  0.32
1980 Cox DR, Epstein LB, Epstein CJ. Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16. Proceedings of the National Academy of Sciences of the United States of America. 77: 2168-72. PMID 6154946  0.32
1979 Epstein CJ, Travis B. Preimplantation lethality of monosomy for mouse chromosome 19. Nature. 280: 144-5. PMID 552603 DOI: 10.1038/280144a0  1
1979 Blau HM, Epstein CJ. Manipulation of myogenesis in vitro: reversible inhibition by DMSO. Cell. 17: 95-108. PMID 455462 DOI: 10.1016/0092-8674(79)90298-8  1
1979 Golbus MS, Loughman WD, Epstein CJ, Halbasch G, Stephens JD, Hall BD. Prenatal genetic diagnosis in 3000 amniocenteses. The New England Journal of Medicine. 300: 157-63. PMID 153471 DOI: 10.1056/NEJM197901253000402  1
1978 Martin GR, Epstein CJ, Martin DW. Use of teratocarcinoma stem cells as a model system for the study of X-chromosome inactivation in vitro. Basic Life Sciences. 12: 269-95. PMID 752322  0.52
1978 Martin GR, Smith S, Epstein CJ. Protein synthetic patterns in teratocarcinoma stem cells and mouse embryos at early stages of development. Developmental Biology. 66: 8-16. PMID 751845  0.52
1978 Epstein CJ, Smith S, Travis B, Tucker G. Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos. Nature. 274: 500-3. PMID 672979 DOI: 10.1038/274500a0  1
1978 Martin GR, Epstein CJ, Travis B, Tucker G, Yatziv S, Martin DW, Clift S, Cohen S. X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro. Nature. 271: 329-33. PMID 563984  0.52
1978 Epstein CJ, Smith SA. Handling of actinomycin D by preimplantation mouse embryos. Experimental Cell Research. 111: 117-26. PMID 563792  0.32
1978 Epstein CJ, Travis B, Tucker G, Smith S. The direct demonstration of an X-chromosome dosage effect prior to inactivation. Basic Life Sciences. 12: 261-7. PMID 378216  1
1977 Epstein CJ, Tucker G, Travis B, Gropp A. Gene dosage for isocitrate dehydrogenase in mouse embryos trisomic for chromosome 1. Nature. 267: 615-6. PMID 876380 DOI: 10.1038/267615a0  1
1977 Neufeld EF, Liebaers I, Epstein CJ, Yatziv S, Milunsky A, Migeon BR. The Hunter syndrome in females: is there an autosomal recessive form of iduronate sulfatase deficiency? American Journal of Human Genetics. 29: 455-61. PMID 409284  1
1976 Hynes RO, Martin GS, Shearer M, Critchley DR, Epstein CJ. Viral transformation of rat myoblasts: effects on fusion and surface properties. Developmental Biology. 48: 35-46. PMID 173598 DOI: 10.1016/0012-1606(76)90043-9  1
1970 Martin GM, Sprague CA, Epstein CJ. Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Laboratory Investigation; a Journal of Technical Methods and Pathology. 23: 86-92. PMID 5431223  0.92
1968 Epstein CJ, Graham CB, Hodgkin WE, Hecht F, Motulsky AG. Hereditary dysplasia of bone with kyphoscoliosis, contractures, and abnormally shaped ears. The Journal of Pediatrics. 73: 379-86. PMID 5667420  1
1966 Epstein CJ, Martin GM, Schultz AL, Motulsky AG. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine. 45: 177-221. PMID 5327241  1
1965 Epstein CJ, Martin GM, Motulsky AG. Werner's syndrome; caricature of aging. A genetic model for the study of degenerative diseases. Transactions of the Association of American Physicians. 78: 73-81. PMID 5864984  1
1965 Epstein CJ, Motulsky AG. Evolutionary origins of human proteins. Progress in Medical Genetics. 4: 85-127. PMID 5319298  1
1964 GOLDBERGER RF, EPSTEIN CJ, ANFINSEN CB. PURIFICATION AND PROPERTIES OF A MICROSOMAL ENZYME SYSTEM CATALYZING THE REACTIVATION OF REDUCED RIBONUCLEASE AND LYSOZYME. The Journal of Biological Chemistry. 239: 1406-10. PMID 14189872  1
1963 EPSTEIN CJ, ANFINSEN CB. THE USE OF GEL FILTRATION IN THE ISOLATION AND PURIFICATION OF BEEF INSULIN. Biochemistry. 2: 461-4. PMID 14069529  1
1963 GOLDBERGER RF, EPSTEIN CJ, ANFINSEN CB. Acceleration of reactivation of reduced bovine pancreatic ribonuclease by a microsomal system from rat liver. The Journal of Biological Chemistry. 238: 628-35. PMID 13948694  1
1962 EPSTEIN CJ, ANFINSEN CB. The reversible reduction of disulfide bonds in trypsin and ribonuclease coupled to carboxymethyl cellulose. The Journal of Biological Chemistry. 237: 2175-9. PMID 13890416  1
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