Costin Tomescu, Ph.D. - Publications

Affiliations: 
2004 University of Virginia, Charlottesville, VA 
Area:
Microbiology Biology, Immunology, Oncology, Molecular Biology

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Adeniji OS, Kuri-Cervantes L, Yu C, Xu Z, Ho M, Chew GM, Shikuma C, Tomescu C, George AF, Roan NR, Ndhlovu LC, Liu Q, Muthumani K, Weiner DB, Betts MR, et al. Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells. Plos Pathogens. 17: e1010034. PMID 34762717 DOI: 10.1371/journal.ppat.1010034  0.402
2021 Tomescu C, Kroll K, Colon K, Papasavvas E, Frank I, Tebas P, Mounzer K, Reeves RK, Montaner LJ. Identification of the predominant human NK cell effector subset mediating ADCC against HIV-infected targets coated with BNAbs or plasma from PLWH. European Journal of Immunology. PMID 34086344 DOI: 10.1002/eji.202149188  0.368
2020 Tomescu C, Colon K, Smith P, Taylor M, Azzoni L, Metzger DS, Montaner LJ. Persons who inject drugs (PWID) retain functional NK cells, dendritic cell stimulation, and adaptive immune recall responses despite prolonged opioid use. Journal of Leukocyte Biology. PMID 33289158 DOI: 10.1002/JLB.5A0920-604R  0.422
2018 Cai Y, Abdel-Mohsen M, Tomescu C, Xue F, Wu G, Howell BJ, Ai Y, Sun J, Azzoni L, Le Coz C, Romberg N, Montaner LJ. BCL6 Inhibitor-mediated Downregulation of pSAMHD1 and T Cell Activation Are Associated with Decreased HIV Infection and Reactivation. Journal of Virology. PMID 30355686 DOI: 10.1128/Jvi.01073-18  0.322
2018 Bertagnolli LN, White JA, Simonetti FR, Beg SA, Lai J, Tomescu C, Murray AJ, Antar AAR, Zhang H, Margolick JB, Hoh R, Deeks SG, Tebas P, Montaner LJ, Siliciano RF, et al. The role of CD32 during HIV-1 infection. Nature. 561: E17-E19. PMID 30232425 DOI: 10.1038/S41586-018-0494-3  0.388
2017 Tomescu C, Tebas P, Montaner LJ. IFN-α augments natural killer-mediated antibody-dependent cellular cytotoxicity of HIV-1-infected autologous CD4+ T cells regardless of major histocompatibility complex class 1 downregulation. Aids (London, England). 31: 613-622. PMID 28225449 DOI: 10.1097/QAD.0000000000001380  0.365
2017 Tomescu C, Tebas P, Montaner LJ. IFN-α augments NK-mediated antibody-dependent cellular cytotoxicity (ADCC) of HIV-1 infected autologous CD4+ T cells regardless of MHC-I downregulation. Aids (London, England). PMID 28060015 DOI: 10.1097/QAD.0000000000001380  0.352
2015 Tomescu C, Mavilio D, Montaner LJ. Lysis of HIV-1-infected autologous CD4+ primary T cells by interferon-alpha-activated NK cells requires NKp46 and NKG2D. Aids (London, England). 29: 1767-73. PMID 26372382 DOI: 10.1097/QAD.0000000000000777  0.414
2014 Tomescu C, Liu Q, Ross BN, Yin X, Lynn K, Mounzer KC, Kostman JR, Montaner LJ. A correlate of HIV-1 control consisting of both innate and adaptive immune parameters best predicts viral load by multivariable analysis in HIV-1 infected viremic controllers and chronically-infected non-controllers. Plos One. 9: e103209. PMID 25078947 DOI: 10.1371/journal.pone.0103209  0.413
2012 Tomescu C, Duh FM, Hoh R, Viviani A, Harvill K, Martin MP, Carrington M, Deeks SG, Montaner LJ. Impact of protective killer inhibitory receptor/human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers. Aids (London, England). 26: 1869-78. PMID 22874514 DOI: 10.1097/QAD.0b013e32835861b0  0.358
2011 Tomescu C, Abdulhaqq S, Montaner LJ. Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN) Clinical and Experimental Immunology. 164: 158-169. PMID 21413945 DOI: 10.1111/j.1365-2249.2011.04379.x  0.316
2010 Chehimi J, Papasavvas E, Tomescu C, Gekonge B, Abdulhaqq S, Raymond A, Hancock A, Vinekar K, Carty C, Reynolds G, Pistilli M, Mounzer K, Kostman J, Montaner LJ. Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand. Journal of Virology. 84: 2762-73. PMID 20042498 DOI: 10.1128/Jvi.01350-09  0.371
2009 Tomescu C, Chehimi J, Maino VC, Montaner LJ. Retention of viability, cytotoxicity, and response to IL-2, IL-15, or IFN-alpha by human NK cells after CD107a degranulation. Journal of Leukocyte Biology. 85: 871-6. PMID 19237639 DOI: 10.1189/jlb.1008635  0.346
2007 Chehimi J, Azzoni L, Farabaugh M, Creer SA, Tomescu C, Hancock A, Mackiewicz A, D'Alessandro L, Ghanekar S, Foulkes AS, Mounzer K, Kostman J, Montaner LJ. Baseline viral load and immune activation determine the extent of reconstitution of innate immune effectors in HIV-1-infected subjects undergoing antiretroviral treatment. Journal of Immunology (Baltimore, Md. : 1950). 179: 2642-50. PMID 17675528 DOI: 10.4049/Jimmunol.179.4.2642  0.444
2007 Tomescu C, Chehimi J, Maino VC, Montaner LJ. NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for IFN-mediated NK activation by plasmacytoid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 2097-104. PMID 17675468  0.398
2007 Adang LA, Tomescu C, Law WK, Kedes DH. Intracellular Kaposi's sarcoma-associated herpesvirus load determines early loss of immune synapse components. Journal of Virology. 81: 5079-90. PMID 17329329 DOI: 10.1128/Jvi.02738-06  0.363
2003 Tomescu C, Law WK, Kedes DH. Surface downregulation of major histocompatibility complex class I, PE-CAM, and ICAM-1 following de novo infection of endothelial cells with Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 77: 9669-84. PMID 12915579 DOI: 10.1128/Jvi.77.17.9669-9684.2003  0.568
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