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Derek A. Drechsel, Ph.D. - Publications

Affiliations: 
2010 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Toxicology, Neuroscience Biology
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15/27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Chang CH, Drechsel DA, Kitson RR, Siegel D, You Q, Backos DS, Ju C, Moody CJ, Ross D. 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity. Molecular Pharmacology. 85: 849-57. PMID 24682466 DOI: 10.1124/Mol.113.090654  0.323
2014 Chang C, Drechsel DA, Kitson RRA, Siegel D, You Q, Backos DS, Ju C, Moody CJ, Ross D. Abstract 1788: 19-Substituted benzoquinone ansamycins. Hsp90 inhibitors with decreased off-target toxicity Cancer Research. 74: 1788-1788. DOI: 10.1158/1538-7445.Am2014-1788  0.313
2012 Drechsel DA, Estévez AG, Barbeito L, Beckman JS. Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS. Neurotoxicity Research. 22: 251-64. PMID 22488161 DOI: 10.1007/S12640-012-9322-Y  0.38
2011 Durazo SA, Kadam RS, Drechsel D, Patel M, Kompella UB. Brain mitochondrial drug delivery: influence of drug physicochemical properties. Pharmaceutical Research. 28: 2833-47. PMID 21796482 DOI: 10.1007/S11095-011-0532-4  0.474
2011 Cantu D, Fulton RE, Drechsel DA, Patel M. Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂. Journal of Neurochemistry. 118: 79-92. PMID 21517855 DOI: 10.1111/J.1471-4159.2011.07290.X  0.642
2010 Drechsel DA, Patel M. Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system. The Journal of Biological Chemistry. 285: 27850-8. PMID 20558743 DOI: 10.1074/Jbc.M110.101196  0.603
2010 Cantu D, Fulton R, Drechsel D, Patel M. Mitochondrial Aconitase Knockdown Decreases Cellular Metabolism and Prevents Paraquat-dependent Dopaminergic Neuronal Death Free Radical Biology and Medicine. 49: S154. DOI: 10.1016/J.Freeradbiomed.2010.10.432  0.614
2009 Chick WS, Drechsel DA, Hammond W, Patel M, Johnson TE. Transmission of mutant phenotypes from ES cells to adult mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 734-40. PMID 19795169 DOI: 10.1007/S00335-009-9228-Z  0.457
2009 Drechsel DA, Patel M. Differential contribution of the mitochondrial respiratory chain complexes to reactive oxygen species production by redox cycling agents implicated in parkinsonism. Toxicological Sciences : An Official Journal of the Society of Toxicology. 112: 427-34. PMID 19767442 DOI: 10.1093/Toxsci/Kfp223  0.597
2009 Drechsel DA, Patel M. Chapter 21 Paraquat-induced production of reactive oxygen species in brain mitochondria. Methods in Enzymology. 456: 381-93. PMID 19348900 DOI: 10.1016/S0076-6879(08)04421-2  0.598
2008 Drechsel DA, Patel M. Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease. Free Radical Biology & Medicine. 44: 1873-86. PMID 18342017 DOI: 10.1016/J.Freeradbiomed.2008.02.008  0.505
2008 Castello PR, Drechsel DA, Day BJ, Patel M. Inhibition of mitochondrial hydrogen peroxide production by lipophilic metalloporphyrins. The Journal of Pharmacology and Experimental Therapeutics. 324: 970-6. PMID 18063723 DOI: 10.1124/Jpet.107.132134  0.587
2008 Drechsel DA, Patel M. Corrigendum to "Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease" [Free Radic. Biol. Med. 44 (2008) 1873-1886] (DOI:10.1016/j.freeradbiomed.2008.02.008) Free Radical Biology and Medicine. 45: 1045. DOI: 10.1016/J.Freeradbiomed.2008.07.005  0.473
2007 Drechsel DA, Liang LP, Patel M. 1-methyl-4-phenylpyridinium-induced alterations of glutathione status in immortalized rat dopaminergic neurons. Toxicology and Applied Pharmacology. 220: 341-8. PMID 17395226 DOI: 10.1016/J.Taap.2007.02.002  0.535
2007 Castello PR, Drechsel DA, Patel M. Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. The Journal of Biological Chemistry. 282: 14186-93. PMID 17389593 DOI: 10.1074/Jbc.M700827200  0.607
Low-probability matches (unlikely to be authored by this person)
2013 Trias E, Díaz-Amarilla P, Olivera-Bravo S, Isasi E, Drechsel DA, Lopez N, Bradford CS, Ireton KE, Beckman JS, Barbeito L. Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS. Frontiers in Cellular Neuroscience. 7: 274. PMID 24399933 DOI: 10.3389/Fncel.2013.00274  0.289
2016 Gaffney SH, Grespin M, Garnick L, Drechsel DA, Hazan R, Paustenbach DJ, Simmons BD. Anthophyllite asbestos: state of the science review. Journal of Applied Toxicology : Jat. PMID 27397058 DOI: 10.1002/Jat.3356  0.288
2018 Drechsel DA, Towle KM, Fung ES, Novick RM, Paustenbach DJ, Monnot AD. Skin Sensitization Induction Potential From Daily Exposure to Fragrances in Personal Care Products. Dermatitis : Contact, Atopic, Occupational, Drug. 29: 324-331. PMID 30422886 DOI: 10.1097/Der.0000000000000412  0.286
2012 Drechsel DA, Zielonka J, Kalyanaraman B, Beckman J. Peroxynitrite Formation from Re-Oxidation of Zinc-Deficient Superoxide Dismutase: Implications in Amyotrophic Lateral Sclerosis Free Radical Biology and Medicine. 53: S20. DOI: 10.1016/J.Freeradbiomed.2012.10.044  0.284
2018 Fung E, Drechsel D, Towle K, Hoang M, Novick R, Poteete C, Paustenbach D, Monnot A. Screening-Level Safety Assessment of Personal Care Product Constituents Using Publicly Available Data Cosmetics. 5: 38. DOI: 10.3390/Cosmetics5020038  0.275
2019 Monnot AD, Towle KM, Warshaw EM, Fung ES, Novick RM, Paustenbach DJ, Drechsel DA. Skin Sensitization Induction Risk Assessment of Common Ingredients in Commercially Available Cleansing Conditioners. Dermatitis : Contact, Atopic, Occupational, Drug. PMID 30829810 DOI: 10.1097/Der.0000000000000445  0.274
2018 Fung ES, Novick RM, Drechsel DA, Towle KM, Paustenbach DJ, Monnot AD. Tier-based skin irritation testing of hair cleansing conditioners and their constituents. Cutaneous and Ocular Toxicology. 1-15. PMID 30124079 DOI: 10.1080/15569527.2018.1512610  0.268
2014 Drechsel DA, Chang C, Kitson R, Siegel D, Moody CJ, Ross D. Abstract 1791: 19-Substituted benzoquinone ansamycin Hsp90 inhibitors: Effects on Hsp90 co-chaperones and Hsp90-Hsf1 complexes in cellular systems Cancer Research. 74: 1791-1791. DOI: 10.1158/1538-7445.Am2014-1791  0.267
2018 Towle KM, Drechsel DA, Warshaw EM, Fung ES, Novick RM, Paustenbach DJ, Monnot AD. A Quantitative Risk Assessment of the Skin Sensitization Induction Potential of the Kathon CG Preservative in Rinse-off and Leave-on Personal Care and Cosmetic Products. Dermatitis : Contact, Atopic, Occupational, Drug. PMID 29570489 DOI: 10.1097/Der.0000000000000359  0.261
2017 Drechsel DA, Barlow CA, Bare JL, Jacobs NF, Henshaw JL. Historical evolution of regulatory standards for occupational and consumer exposures to industrial talc. Regulatory Toxicology and Pharmacology : Rtp. 92: 251-267. PMID 29233769 DOI: 10.1016/J.Yrtph.2017.12.005  0.247
2018 Drechsel D, Towle K, Fung E, Novick R, Paustenbach D, Monnot A. Chemical Stability Analysis of Hair Cleansing Conditioners under High-Heat Conditions Experienced during Hair Styling Processes Cosmetics. 5: 23. DOI: 10.3390/Cosmetics5010023  0.243
2007 Sampey BP, Carbone DL, Doorn JA, Drechsel DA, Petersen DR. 4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction. Molecular Pharmacology. 71: 871-83. PMID 17164404 DOI: 10.1124/Mol.106.029686  0.15
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