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Jason S. Stumhofer, Ph.D. - Publications

Affiliations: 
2004 Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Molecular Biology, Microbiology Biology
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 O'Neal KA, Zeltner SL, Foscue CL, Stumhofer JS. Bhlhe40 limits early IL-10 production from CD4 T cells during 17X infection. Infection and Immunity. e0036723. PMID 37843306 DOI: 10.1128/iai.00367-23  0.671
2020 Latham LE, Wikenheiser DJ, Stumhofer JS. ICOS signaling promotes a secondary humoral response after re-challenge with Plasmodium chabaudi chabaudi AS. Plos Pathogens. 16: e1008527. PMID 32348365 DOI: 10.1371/Journal.Ppat.1008527  0.448
2019 Tait Wojno ED, Hunter CA, Stumhofer JS. The Immunobiology of the Interleukin-12 Family: Room for Discovery. Immunity. 50: 851-870. PMID 30995503 DOI: 10.1016/J.Immuni.2019.03.011  0.743
2018 Wikenheiser DJ, Brown SL, Lee J, Stumhofer JS. NK1.1 Expression Defines a Population of CD4 Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Infection. Frontiers in Immunology. 9: 2277. PMID 30374346 DOI: 10.3389/Fimmu.2018.02277  0.501
2017 Ghosh D, Brown SL, Stumhofer JS. IL-17 Promotes Differentiation of Splenic LSK(-) Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28733485 DOI: 10.4049/Jimmunol.1601972  0.663
2016 Wikenheiser DJ, Stumhofer JS. ICOS Co-Stimulation: Friend or Foe? Frontiers in Immunology. 7: 304. PMID 27559335 DOI: 10.3389/Fimmu.2016.00304  0.465
2016 Ghosh D, Wikenheiser DJ, Kennedy B, McGovern KE, Stuart JD, Wilson EH, Stumhofer JS. An Atypical Splenic B Cell Progenitor Population Supports Antibody Production during Plasmodium Infection in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 27448588 DOI: 10.4049/Jimmunol.1502199  0.617
2015 Wikenheiser DJ, Ghosh D, Kennedy B, Stumhofer JS. The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26667167 DOI: 10.4049/Jimmunol.1403206  0.472
2014 Liu FD, Kenngott EE, Schröter MF, Kühl A, Jennrich S, Watzlawick R, Hoffmann U, Wolff T, Norley S, Scheffold A, Stumhofer JS, Saris CJ, Schwab JM, Hunter CA, Debes GF, et al. Timed action of IL-27 protects from immunopathology while preserving defense in influenza. Plos Pathogens. 10: e1004110. PMID 24809349 DOI: 10.1371/Journal.Ppat.1004110  0.778
2013 Stumhofer JS, Loke P. Parasites: what are they good for? Current Immunology Reviews. 9: 120-128. PMID 24683385 DOI: 10.2174/1573395509666131203001449  0.302
2013 Stumhofer JS, Silver JS, Hunter CA. IL-21 is required for optimal antibody production and T cell responses during chronic Toxoplasma gondii infection. Plos One. 8: e62889. PMID 23667536 DOI: 10.1371/Journal.Pone.0062889  0.878
2012 Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, Pritchard GH, Silver JS, Bouladoux N, Stumhofer JS, Harris TH, Grainger J, Wojno ED, Wagage S, Roos DS, et al. The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 37: 511-23. PMID 22981537 DOI: 10.1016/j.immuni.2012.06.014  0.756
2012 Villegas-Mendez A, Greig R, Shaw TN, de Souza JB, Gwyer Findlay E, Stumhofer JS, Hafalla JC, Blount DG, Hunter CA, Riley EM, Couper KN. IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. Journal of Immunology (Baltimore, Md. : 1950). 189: 968-79. PMID 22723523 DOI: 10.4049/Jimmunol.1200688  0.603
2011 Wojno ED, Hosken N, Stumhofer JS, O'Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA. A role for IL-27 in limiting T regulatory cell populations. Journal of Immunology (Baltimore, Md. : 1950). 187: 266-73. PMID 21622862 DOI: 10.4049/Jimmunol.1004182  0.866
2011 Silver JS, Stumhofer JS, Passos S, Ernst M, Hunter CA. IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 187: 350-60. PMID 21606248 DOI: 10.4049/Jimmunol.1004144  0.864
2011 Aronson LR, Stumhofer JS, Drobatz KJ, Hunter CA. Effect of cyclosporine, dexamethasone, and human CTLA4-Ig on production of cytokines in lymphocytes of clinically normal cats and cats undergoing renal transplantation. American Journal of Veterinary Research. 72: 541-9. PMID 21453156 DOI: 10.2460/Ajvr.72.4.541  0.487
2011 Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 409-19. PMID 20826539 DOI: 10.1096/Fj.10-166843  0.77
2010 Stumhofer JS, Tait ED, Quinn WJ, Hosken N, Spudy B, Goenka R, Fielding CA, O'Hara AC, Chen Y, Jones ML, Saris CJ, Rose-John S, Cua DJ, Jones SA, Elloso MM, et al. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nature Immunology. 11: 1119-26. PMID 21057510 DOI: 10.1038/Ni.1957  0.842
2010 Findlay EG, Greig R, Stumhofer JS, Hafalla JC, de Souza JB, Saris CJ, Hunter CA, Riley EM, Couper KN. Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 2482-92. PMID 20631310 DOI: 10.4049/Jimmunol.0904019  0.766
2010 Passos ST, Silver JS, O'Hara AC, Sehy D, Stumhofer JS, Hunter CA. IL-6 promotes NK cell production of IL-17 during toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). 184: 1776-83. PMID 20083665 DOI: 10.4049/Jimmunol.0901843  0.85
2010 Silver JS, Stumhofer JS, Hunter CA. PS3-49 IL-6 is required for the generation of T follicular helper cells during Toxoplasma gondii infection Cytokine. 52: 91-92. DOI: 10.1016/J.Cyto.2010.07.388  0.843
2009 Anderson CF, Stumhofer JS, Hunter CA, Sacks D. IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection. Journal of Immunology (Baltimore, Md. : 1950). 183: 4619-27. PMID 19748991 DOI: 10.4049/Jimmunol.0804024  0.814
2009 Diveu C, McGeachy MJ, Boniface K, Stumhofer JS, Sathe M, Joyce-Shaikh B, Chen Y, Tato CM, McClanahan TK, de Waal Malefyt R, Hunter CA, Cua DJ, Kastelein RA. IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 5748-56. PMID 19380822 DOI: 10.4049/Jimmunol.0801162  0.883
2009 Silver JS, Stumhofer JS, Hunter CA. IL-6 is required for the generation of T follicular helper CD4 T cells during Toxoplasma gondii infection Cytokine. 48: 71. DOI: 10.1016/J.Cyto.2009.07.235  0.803
2008 Stumhofer JS, Hunter CA. Advances in understanding the anti-inflammatory properties of IL-27 Immunology Letters. 117: 123-130. PMID 18378322 DOI: 10.1016/J.Imlet.2008.01.011  0.796
2008 LaRosa DF, Stumhofer JS, Gelman AE, Rahman AH, Taylor DK, Hunter CA, Turka LA. T cell expression of MyD88 is required for resistance to Toxoplasma gondii. Proceedings of the National Academy of Sciences of the United States of America. 105: 3855-60. PMID 18308927 DOI: 10.1073/Pnas.0706663105  0.799
2007 Stumhofer JS, Silver J, Hunter CA. Negative regulation of Th17 responses. Seminars in Immunology. 19: 394-9. PMID 18221887 DOI: 10.1016/J.Smim.2007.11.006  0.73
2007 Stumhofer JS, Silver JS, Laurence A, Porrett PM, Harris TH, Turka LA, Ernst M, Saris CJ, O'Shea JJ, Hunter CA. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nature Immunology. 8: 1363-71. PMID 17994025 DOI: 10.1038/Ni1537  0.899
2007 Dzierszinski F, Pepper M, Stumhofer JS, LaRosa DF, Wilson EH, Turka LA, Halonen SK, Hunter CA, Roos DS. Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infection and Immunity. 75: 5200-9. PMID 17846116 DOI: 10.1128/Iai.00954-07  0.775
2007 Villarino AV, Tato CM, Stumhofer JS, Yao Z, Cui YK, Hennighausen L, O'Shea JJ, Hunter CA. Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals Journal of Experimental Medicine. 204: 65-71. PMID 17227909 DOI: 10.1084/Jem.20061198  0.886
2007 Stumhofer JS, Silver J, Laurence A, Porrett PM, Turka LA, Ernst M, Saris CJ, O′Shea JJ, Hunter CA. 146 A Central Role for Interleukin 27 and IL-6 Mediated Activation of STAT3 in T Cell Production of IL-10 Cytokine. 39: 40-41. DOI: 10.1016/J.Cyto.2007.07.151  0.885
2006 Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, Johnson LM, Villarino AV, Huang Q, Yoshimura A, Sehy D, Saris CJ, O'Shea JJ, Hennighausen L, Ernst M, Hunter CA. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nature Immunology. 7: 937-45. PMID 16906166 DOI: 10.1038/Ni1376  0.871
2006 Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. The Journal of Clinical Investigation. 116: 1317-26. PMID 16670771 DOI: 10.1172/Jci25308  0.832
2006 Villarino AV, Stumhofer JS, Saris CJM, Kastelein RA, De Sauvage FJ, Hunter CA. IL-27 limits IL-2 production during Th1 differentiation Journal of Immunology. 176: 237-247. PMID 16365415 DOI: 10.4049/Jimmunol.176.1.237  0.885
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