Nicole M. Ashpole, Ph.D. - Publications

Affiliations: 
2012 Neuroscience Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Neuroscience Biology, Genetics, General Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordrecht, Netherlands). PMID 27613724 DOI: 10.1007/s11357-016-9931-0  1
2016 Tarantini S, Giles CB, Wren JD, Ashpole NM, Valcarcel-Ares MN, Wei JY, Sonntag WE, Ungvari Z, Csiszar A. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordrecht, Netherlands). PMID 27566308 DOI: 10.1007/s11357-016-9943-9  1
2016 Ashpole NM, Herron JC, Estep PN, Logan S, Hodges EL, Yabluchanskiy A, Humphrey MB, Sonntag WE. Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice. Age (Dordrecht, Netherlands). 38: 38. PMID 26968399 DOI: 10.1007/s11357-016-9902-5  1
2015 Ashpole NM, Herron JC, Mitschelen MC, Farley JA, Logan S, Yan H, Ungvari Z, Hodges EL, Csiszar A, Ikeno Y, Humphrey MB, Sonntag WE. IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26260312 DOI: 10.1002/jbmr.2689  1
2015 Toth P, Tarantini S, Ashpole NM, Tucsek Z, Milne GL, Valcarcel-Ares NM, Menyhart A, Farkas E, Sonntag WE, Csiszar A, Ungvari Z. IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. PMID 26172407 DOI: 10.1111/acel.12372  1
2015 Lee WH, Xu Z, Ashpole NM, Hudmon A, Kulkarni PM, Thakur GA, Lai YY, Hohmann AG. Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics. Neuropharmacology. PMID 26071110 DOI: 10.1016/j.neuropharm.2015.05.038  1
2015 Springo Z, Toth P, Tarantini S, Ashpole NM, Tucsek Z, Sonntag WE, Csiszar A, Koller A, Ungvari ZI. Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 527-30. PMID 25605292 DOI: 10.1038/jcbfm.2014.256  1
2015 Ashpole NM, Sanders JE, Hodges EL, Yan H, Sonntag WE. Growth hormone, insulin-like growth factor-1 and the aging brain. Experimental Gerontology. 68: 76-81. PMID 25300732 DOI: 10.1016/j.exger.2014.10.002  1
2014 Yan H, Mitschelen M, Toth P, Ashpole NM, Farley JA, Hodges EL, Warrington JP, Han S, Fung KM, Csiszar A, Ungvari Z, Sonntag WE. Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 1353-62. PMID 25098324 DOI: 10.1093/gerona/glu118  1
2014 Ashpole NM, Warrington JP, Mitschelen MC, Yan H, Sosnowska D, Gautam T, Farley JA, Csiszar A, Ungvari Z, Sonntag WE. Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells. American Journal of Physiology. Heart and Circulatory Physiology. 307: H858-68. PMID 25038144 DOI: 10.1152/ajpheart.00308.2014  1
2014 Toth P, Tarantini S, Tucsek Z, Ashpole NM, Sosnowska D, Gautam T, Ballabh P, Koller A, Sonntag WE, Csiszar A, Ungvari Z. Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. American Journal of Physiology. Heart and Circulatory Physiology. 306: H299-308. PMID 24322615 DOI: 10.1152/ajpheart.00744.2013  1
2013 Ashpole NM, Chawla AR, Martin MP, Brustovetsky T, Brustovetsky N, Hudmon A. Loss of calcium/calmodulin-dependent protein kinase II activity in cortical astrocytes decreases glutamate uptake and induces neurotoxic release of ATP. The Journal of Biological Chemistry. 288: 14599-611. PMID 23543737 DOI: 10.1074/jbc.M113.466235  1
2012 Song W, Xiao Y, Chen H, Ashpole NM, Piekarz AD, Ma P, Hudmon A, Cummins TR, Shou W. The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity. The Journal of Physiology. 590: 5123-39. PMID 22826127 DOI: 10.1113/jphysiol.2012.235374  1
2012 Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A. Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites. The Journal of Biological Chemistry. 287: 19856-69. PMID 22514276 DOI: 10.1074/jbc.M111.322537  1
2012 Ashpole NM, Song W, Brustovetsky T, Engleman EA, Brustovetsky N, Cummins TR, Hudmon A. Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability. The Journal of Biological Chemistry. 287: 8495-506. PMID 22253441 DOI: 10.1074/jbc.M111.323915  1
2011 Brittain JM, Chen L, Wilson SM, Brustovetsky T, Gao X, Ashpole NM, Molosh AI, You H, Hudmon A, Shekhar A, White FA, Zamponi GW, Brustovetsky N, Chen J, Khanna R. Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2). The Journal of Biological Chemistry. 286: 37778-92. PMID 21832084 DOI: 10.1074/jbc.M111.255455  1
2011 Coultrap SJ, Vest RS, Ashpole NM, Hudmon A, Bayer KU. CaMKII in cerebral ischemia. Acta Pharmacologica Sinica. 32: 861-72. PMID 21685929 DOI: 10.1038/aps.2011.68  1
2011 Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, ... ... Ashpole NM, et al. Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. Nature Medicine. 17: 822-9. PMID 21642979 DOI: 10.1038/nm.2345  1
2011 Li L, Khanna M, Jo I, Wang F, Ashpole NM, Hudmon A, Meroueh SO. Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferation. Journal of Chemical Information and Modeling. 51: 755-9. PMID 21438548 DOI: 10.1021/ci100490w  1
2011 Ashpole NM, Hudmon A. Excitotoxic neuroprotection and vulnerability with CaMKII inhibition. Molecular and Cellular Neurosciences. 46: 720-30. PMID 21316454 DOI: 10.1016/j.mcn.2011.02.003  1
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